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Mark Walker

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Emma L Edghill; Sian Ellard; Graham A Hitman; A Khamis; Mark I McCarthy; K R Owen; A T Hattersley; Mark Walker; Michael Weedon; T M Frayling
Sequencing PDX1 (insulin promoter factor 1) in 1788 UK individuals found 5% had a low frequency coding variant, but these variants are not associated with Type 2 diabetes.
Linda Penn; Martin White; John Oldroyd; Mark Walker; K George M M Alberti; John C Mathers
Prevention of type 2 diabetes in adults with impaired glucose tolerance: the European Diabetes Prevention RCT in Newcastle upon Tyne, UK.
Inês Barroso; Jian'an Luan; Eleanor Wheeler; Pamela Whittaker; Jon Wasson; Eleftheria Zeggini; Michael N Weedon; Sarah Hunt; Ranganath Venkatesh; Timothy M Frayling; Marcos Delgado; Rosalind J Neuman; Jinghua Zhao; Richard Sherva; Benjamin Glaser; Mark Walker; Graham A Hitman; Mark I McCarthy; Andrew T Hattersley; M Alan Permutt; Nicholas J Wareham; Panos Deloukas
Population-specific risk of type 2 diabetes conferred by HNF4A P2 promoter variants: a lesson for replication studies.

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All Publications

2011: Emma L Edghill; Sian Ellard; Graham A Hitman; A Khamis; Mark I McCarthy; K R Owen; A T Hattersley; Mark Walker; Michael Weedon; T M Frayling
Sequencing PDX1 (insulin promoter factor 1) in 1788 UK individuals found 5% had a low frequency coding variant, but these variants are not associated with Type 2 diabetes.
Diabetic medicine : a journal of the British Diabetic Association 2011;28(6):681-4.
2009: Linda Penn; Martin White; John Oldroyd; Mark Walker; K George M M Alberti; John C Mathers
Prevention of type 2 diabetes in adults with impaired glucose tolerance: the European Diabetes Prevention RCT in Newcastle upon Tyne, UK.
BMC public health 2009;9():342.
2008: Inês Barroso; Jian'an Luan; Eleanor Wheeler; Pamela Whittaker; Jon Wasson; Eleftheria Zeggini; Michael N Weedon; Sarah Hunt; Ranganath Venkatesh; Timothy M Frayling; Marcos Delgado; Rosalind J Neuman; Jinghua Zhao; Richard Sherva; Benjamin Glaser; Mark Walker; Graham A Hitman; Mark I McCarthy; Andrew T Hattersley; M Alan Permutt; Nicholas J Wareham; Panos Deloukas
Population-specific risk of type 2 diabetes conferred by HNF4A P2 promoter variants: a lesson for replication studies.
Diabetes 2008;57(11):3161-5.
2008: Lynsey M Cree; S K Patel; A Pyle; Stephen Lynn; Douglass M Turnbull; Patrick F Chinnery; Mark Walker
Age-related decline in mitochondrial DNA copy number in isolated human pancreatic islets.
Diabetologia 2008;51(8):1440-3.
2008: R Murphy; D M Turnbull; Mark Walker; Andrew T Hattersley
Clinical features, diagnosis and management of maternally inherited diabetes and deafness (MIDD) associated with the 3243A>G mitochondrial point mutation.
Diabetic medicine : a journal of the British Diabetic Association 2008;25(4):383-99.
2007: Laura Pascoe; Andrea Tura; Sheila K Patel; Ibrahim M Ibrahim; Ele Ferrannini; Eleftheria Zeggini; Michael Weedon; Andrea Mari; Andrew T Hattersley; Mark I McCarthy; Timothy M Frayling; Mark Walker
Common variants of the novel type 2 diabetes genes CDKAL1 and HHEX/IDE are associated with decreased pancreatic beta-cell function.
Diabetes 2007;56(12):3101-4.
2007: Roger G Whittaker; Andrew M Schaefer; Robert McFarland; Robert W Taylor; Mark Walker; Douglass M Turnbull
Prevalence and progression of diabetes in mitochondrial disease.
Diabetologia 2007;50(10):2085-9.
2007: M K Jayapaul; Mark Walker
Hyperglucagonaemia is not a primary metabolic defect in non-diabetic first-degree relatives from Type 2 diabetic families.
Diabetic medicine : a journal of the British Diabetic Association 2007;24(9):1050-1.
2007: Roger G Whittaker; Andrew M Schaefer; Robert McFarland; Robert W Taylor; Mark Walker; Douglass M Turnbull
Diabetes and deafness: is it sufficient to screen for the mitochondrial 3243A>G mutation alone?
Diabetes care 2007;30(9):2238-9.
2007: Manjinder S Sandhu; Michael Weedon; Katherine A Fawcett; Jon Wasson; Sally L Debenham; Allan Daly; Hana Lango; Timothy M Frayling; Rosalind J Neumann; Richard Sherva; Ilana Blech; Paul D P Pharoah; Colin N A Palmer; Charlotte Kimber; Roger Tavendale; Andrew D Morris; Mark I McCarthy; Mark Walker; Graham A Hitman; Benjamin Glaser; M Alan Permutt; Andrew T Hattersley; Nicholas J Wareham; Inês Barroso
Common variants in WFS1 confer risk of type 2 diabetes.
Nature genetics 2007;39(8):951-3.
2007: Audrey E Brown; Stephen J Yeaman; Mark Walker
Targeted suppression of calpain-10 expression impairs insulin-stimulated glucose uptake in cultured primary human skeletal muscle cells.
Molecular genetics and metabolism 2007;91(4):318-24.
2007: Eleftheria Zeggini; Michael N Weedon; Cecilia M Lindgren; Timothy M Frayling; Katherine S Elliott; Hana Lango; Nicholas J Timpson; John R B Perry; Nigel W Rayner; Michael Weedon; Jeffrey C Barrett; Beverley Shields; Andrew P Morris; Sian Ellard; Christopher J Groves; Lorna W Harries; Jonathan Marchini; Katharine R Owen; Beatrice Knight; Lon R Cardon; Mark Walker; Graham A Hitman; Andrew D Morris; Alex S F Doney; Mark I McCarthy; Andrew T Hattersley
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.
Science (New York, N.Y.) 2007;316(5829):1336-41.
2007: Gary J Litherland; Nicholas J Morris; Mark Walker; Stephen J Yeaman
Role of glycogen content in insulin resistance in human muscle cells.
Journal of cellular physiology 2007;211(2):344-52.
2007: laura pickersgill; Gary J Litherland; Andrew S Greenberg; Mark Walker; Stephen J Yeaman
Key role for ceramides in mediating insulin resistance in human muscle cells.
The Journal of biological chemistry 2007;282(17):12583-9.
2007: Katharine R Owen; Christopher J Groves; Robert L Hanson; William C Knowler; Alan R Shuldiner; Steven C Elbein; Braxton D Mitchell; philippe froguel; Maggie C Y Ng; Juliana C Chan; Weiping Jia; Panos Deloukas; Graham A Hitman; Mark Walker; Timothy M Frayling; Andrew T Hattersley; Eleftheria Zeggini; Mark I McCarthy
Common variation in the LMNA gene (encoding lamin A/C) and type 2 diabetes: association analyses in 9,518 subjects.
Diabetes 2007;56(3):879-83.
2007: Minal Desai; Eleftheria Zeggini; Virginia Horton; Katharine R Owen; Andrew T Hattersley; Jonathan C Levy; Mark Walker; K M Gillespie; Polly J Bingley; Graham A Hitman; Rury R Holman; Mark I McCarthy; Anne Clark
An association analysis of the HLA gene region in latent autoimmune diabetes in adults.
Diabetologia 2007;50(1):68-73.
2006: Michael Weedon; Mark I McCarthy; Graham A Hitman; Mark Walker; Christopher J Groves; Eleftheria Zeggini; Nigel W Rayner; Beverley Shields; Katharine R Owen; Andrew T Hattersley; Timothy M Frayling
Combining information from common type 2 diabetes risk polymorphisms improves disease prediction.
PLoS medicine 2006;3(10):e374.
2006: Christopher J Groves; Eleftheria Zeggini; Jayne A L Minton; Timothy M Frayling; Michael Weedon; Nigel W Rayner; Graham A Hitman; Mark Walker; Steven Wiltshire; Andrew T Hattersley; Mark I McCarthy
Association analysis of 6,736 U.K. subjects provides replication and confirms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk.
Diabetes 2006;55(9):2640-4.
2006: Eleftheria Zeggini; Coleen M Damcott; Robert L Hanson; Mohammad A Karim; Nigel W Rayner; Christopher J Groves; Leslie J Baier; Terri C Hale; Andrew T Hattersley; Graham A Hitman; Sarah E Hunt; William C Knowler; Braxton D Mitchell; Maggie C Y Ng; Jeffrey R O'Connell; Toni I Pollin; Martine Vaxillaire; Mark Walker; Xiaoqin Wang; Pamela Whittaker; Kun-san Xiang; Xiang Kunsun; Weiping Jia; Juliana C N Chan; philippe froguel; Panos Deloukas; Alan R Shuldiner; Steven C Elbein; Mark I McCarthy
Variation within the gene encoding the upstream stimulatory factor 1 does not influence susceptibility to type 2 diabetes in samples from populations with replicated evidence of linkage to chromosome 1q.
Diabetes 2006;55(9):2541-8.
2006: Anna L Gloyn; Deborah J G Mackay; Michael Weedon; Mark I McCarthy; Mark Walker; Graham A Hitman; Bridget A Knight; Katharine R Owen; Andrew T Hattersley; Timothy M Frayling
Assessment of the role of common genetic variation in the transient neonatal diabetes mellitus (TNDM) region in type 2 diabetes: a comparative genomic and tagging single nucleotide polymorphism approach.
Diabetes 2006;55(8):2272-6.
2006: Jayne A L Minton; Katharine Owen; Christopher Ricketts; N Crabtree; G Shaikh; Sarah Ehtisham; J R Porter; CM Carey; D Hodge; Richard B Paisey; Mark Walker; Timothy G Barrett
Syndromic obesity and diabetes: changes in body composition with age and mutation analysis of ALMS1 in 12 United Kingdom kindreds with Alstrom syndrome.
The Journal of clinical endocrinology and metabolism 2006;91(8):3110-6.
2006: R Singh; E Pearson; Peter Avery; Mark I McCarthy; J C Levy; G A Hitman; M Sampson; Mark Walker; Andrew T Hattersley
Reduced beta cell function in offspring of mothers with young-onset type 2 diabetes.
Diabetologia 2006;49(8):1876-80.
2006: Minal Desai; Eleftheria Zeggini; Virginia Horton; Katharine R Owen; Andrew T Hattersley; Jonathan C Levy; Graham A Hitman; Mark Walker; Rury R Holman; Mark I McCarthy; Anne Clark
The variable number of tandem repeats upstream of the insulin gene is a susceptibility locus for latent autoimmune diabetes in adults.
Diabetes 2006;55(6):1890-4.
2006: Christopher J Groves; Eleftheria Zeggini; Mark Walker; Graham A Hitman; Jonathan C Levy; Stephen O'Rahilly; Andrew T Hattersley; Mark I McCarthy; Steven Wiltshire
Significant linkage of BMI to chromosome 10p in the U.K. population and evaluation of GAD2 as a positional candidate.
Diabetes 2006;55(6):1884-9.
2006: S Patel; Jayne A L Minton; Michael Weedon; Timothy M Frayling; Christopher Ricketts; Graham A Hitman; Mark I McCarthy; Andrew T Hattersley; Mark Walker; Timothy G Barrett
Common variations in the ALMS1 gene do not contribute to susceptibility to type 2 diabetes in a large white UK population.
Diabetologia 2006;49(6):1209-13.
2006: Michael Weedon; Michael N Weedon; David Melzer; Beverley Shields; Graham A Hitman; Mark Walker; Mark I McCarthy; Andrew T Hattersley; Timothy M Frayling
The functional "KL-VS" variant of KLOTHO is not associated with type 2 diabetes in 5028 UK Caucasians.
BMC medical genetics 2006;7():51.
2006: Michael Weedon; Michael N Weedon; Beverley Shields; Graham A Hitman; Mark Walker; Mark I McCarthy; Andrew T Hattersley; Timothy M Frayling
Functional variation in VEGF is not associated with type 2 diabetes in a United Kingdom Caucasian population.
JOP : Journal of the pancreas 2006;7(3):295-302.
2005: Eleftheria Zeggini; J R C Parkinson; Stephanie Halford; Katharine R Owen; Mark Walker; Graham A Hitman; Jonathan C Levy; Mike J Sampson; Timothy M Frayling; Andrew T Hattersley; Mark I McCarthy
Examining the relationships between the Pro12Ala variant in PPARG and Type 2 diabetes-related traits in UK samples.
Diabetic medicine : a journal of the British Diabetic Association 2005;22(12):1696-700.
2005: Mark Walker; A Mari; M K Jayapaul; S M A Bennett; Ele Ferrannini
Impaired beta cell glucose sensitivity and whole-body insulin sensitivity as predictors of hyperglycaemia in non-diabetic subjects.
Diabetologia 2005;48(12):2470-6.
2005: Eleftheria Zeggini; Christopher J Groves; J R C Parkinson; Stephanie Halford; Katharine R Owen; Timothy M Frayling; Mark Walker; Graham A Hitman; Jonathan C Levy; Stephen O'Rahilly; Andrew T Hattersley; Mark I McCarthy
Large-scale studies of the association between variation at the TNF/LTA locus and susceptibility to type 2 diabetes.
Diabetologia 2005;48(10):2013-7.
2005: Mark Walker; R W Taylor; Douglass M Turnbull
Mitochondrial diabetes.
Diabetic medicine : a journal of the British Diabetic Association 2005;22 Suppl 4():18-20.
2005: Michael Weedon; Katharine R Owen; Beverley Shields; Graham A Hitman; Mark Walker; Mark I McCarthy; Andrew T Hattersley; Timothy M Frayling
A large-scale association analysis of common variation of the HNF1alpha gene with type 2 diabetes in the U.K. Caucasian population.
Diabetes 2005;54(8):2487-91.
2005: L J Logie; A E Brown; Stephen J Yeaman; Mark Walker
Calpain inhibition and insulin action in cultured human muscle cells.
Molecular genetics and metabolism 2005;85(1):54-60.
2004: C F Liew; Christopher J Groves; Steven Wiltshire; Eleftheria Zeggini; Timothy M Frayling; Katharine R Owen; Mark Walker; Graham A Hitman; Jonathan C Levy; Stephen O'Rahilly; Andrew T Hattersley; Desmond G Johnston; Mark I McCarthy
Analysis of the contribution to type 2 diabetes susceptibility of sequence variation in the gene encoding stearoyl-CoA desaturase, a key regulator of lipid and carbohydrate metabolism.
Diabetologia 2004;47(12):2168-75.
2004: Eleftheria Zeggini; James Parkinson; Stephanie Halford; Katharine R Owen; Timothy M Frayling; Mark Walker; Graham A Hitman; Jonathan C Levy; Mike J Sampson; Edith J M Feskens; Andrew T Hattersley; Mark I McCarthy
Association studies of insulin receptor substrate 1 gene (IRS1) variants in type 2 diabetes samples enriched for family history and early age of onset.
Diabetes 2004;53(12):3319-22.
2004: E A McIntyre; Reza Halse; Stephen J Yeaman; Mark Walker
Cultured muscle cells from insulin-resistant type 2 diabetes patients have impaired insulin, but normal 5-amino-4-imidazolecarboxamide riboside-stimulated, glucose uptake.
The Journal of clinical endocrinology and metabolism 2004;89(7):3440-8.
2004: G W Mills; Peter Avery; Mark I McCarthy; Andrew T Hattersley; J C Levy; G A Hitman; M Sampson; Mark Walker
Heritability estimates for beta cell function and features of the insulin resistance syndrome in UK families with an increased susceptibility to type 2 diabetes.
Diabetologia 2004;47(4):732-8.
2004: Robert McFarland; Andrew M Schaefer; Julie L Gardner; Stephen Lynn; Christine M Hayes; Martin J Barron; Mark Walker; Patrick F Chinnery; Robert W Taylor; Douglass M Turnbull
Familial myopathy: new insights into the T14709C mitochondrial tRNA mutation.
Annals of neurology 2004;55(4):478-84.
2003: Timothy M Frayling; Steven Wiltshire; Graham A Hitman; Mark Walker; Jonathan C Levy; Mike Sampson; Christopher J Groves; Stephan Menzel; Mark I McCarthy; Andrew T Hattersley
Young-onset type 2 diabetes families are the major contributors to genetic loci in the Diabetes UK Warren 2 genome scan and identify putative novel loci on chromosomes 8q21, 21q22, and 22q11.
Diabetes 2003;52(7):1857-63.
2003: Christopher J Groves; Steven Wiltshire; Damian Smedley; Katharine R Owen; Timothy M Frayling; Mark Walker; Graham A Hitman; Jonathan C Levy; Stephen O'Rahilly; Stephan Menzel; Andrew T Hattersley; Mark I McCarthy
Association and haplotype analysis of the insulin-degrading enzyme (IDE) gene, a strong positional and biological candidate for type 2 diabetes susceptibility.
Diabetes 2003;52(5):1300-5.
2003: Stephen Lynn; Gillian M Borthwick; Richard M Charnley; Mark Walker; Douglass M Turnbull
Heteroplasmic ratio of the A3243G mitochondrial DNA mutation in single pancreatic beta cells.
Diabetologia 2003;46(2):296-9.
2002: E A McIntyre; Mark Walker
Genetics of type 2 diabetes and insulin resistance: knowledge from human studies.
Clinical endocrinology 2002;57(3):303-11.
2002: Alan T W Choo-Kang; Stephen Lynn; Geoffrey A Taylor; Mark E Daly; Sarbpreet S Sihota; Theresa M Wardell; Patrick F Chinnery; Douglass M Turnbull; Mark Walker
Defining the importance of mitochondrial gene defects in maternally inherited diabetes by sequencing the entire mitochondrial genome.
Diabetes 2002;51(7):2317-20.
2002: Jayne A L Minton; Andrew T Hattersley; Katharine Owen; Mark I McCarthy; Mark Walker; Farida Latif; Timothy Barrett; Timothy M Frayling
Association studies of genetic variation in the WFS1 gene and type 2 diabetes in U.K. populations.
Diabetes 2002;51(4):1287-90.
2002: Steven Wiltshire; Timothy M Frayling; Andrew T Hattersley; Graham A Hitman; Mark Walker; Jonathan C Levy; Stephen O'Rahilly; Christopher J Groves; Stephan Menzel; Lon R Cardon; Mark I McCarthy
Evidence for linkage of stature to chromosome 3p26 in a large U.K. Family data set ascertained for type 2 diabetes.
American journal of human genetics 2002;70(2):543-6.
2002: Stephen Lynn; Julie C Evans; Christopher White; Timothy M Frayling; Andrew T Hattersley; Douglass M Turnbull; Yukio Horikawa; Nancy J Cox; Graeme I Bell; Mark Walker
Variation in the calpain-10 gene affects blood glucose levels in the British population.
Diabetes 2002;51(1):247-50.
2001: T J Butler; L A Barriocanal; Mark Walker
Elevated plasma non-esterified fatty acid levels and insulin secretion in non-diabetic relatives of type 2 diabetic patients.
Clinical endocrinology 2001;55(3):349-55.
2001: Steven Wiltshire; Andrew T Hattersley; Graham A Hitman; Mark Walker; Jonathan C Levy; M Sampson; Stephen O'Rahilly; Timothy M Frayling; J I Bell; G Mark Lathrop; Amanda Bennett; R Dhillon; C Fletcher; Christopher J Groves; E Jones; P Prestwich; N Simecek; PV Rao; Marie Wishart; Gian Franco Bottazzo; R Foxon; S Howell; Damian Smedley; Lon R Cardon; Stephan Menzel; Mark I McCarthy
A genomewide scan for loci predisposing to type 2 diabetes in a U.K. population (the Diabetes UK Warren 2 Repository): analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome 1q.
American journal of human genetics 2001;69(3):553-69.
2001: Julie C Evans; Timothy M Frayling; Paul G Cassell; PJ Saker; Graham A Hitman; Mark Walker; Jonathan C Levy; Stephen O'Rahilly; PV Rao; A J Bennett; E C Jones; Stephan Menzel; P Prestwich; N Simecek; Marie Wishart; R Dhillon; C Fletcher; Ann Millward; Andrew G Demaine; T Wilkin; Y Horikawa; N J Cox; Graeme I Bell; Sian Ellard; Mark I McCarthy; Andrew T Hattersley
Studies of association between the gene for calpain-10 and type 2 diabetes mellitus in the United Kingdom.
American journal of human genetics 2001;69(3):544-52.
2000: Paul G Cassell; PJ Saker; SJ Huxtable; Eleni Kousta; Alan E Jackson; Andrew T Hattersley; Timothy M Frayling; Mark Walker; PG Kopelman; Ambady Ramachandran; C Snehelatha; Graham A Hitman; Mark I McCarthy
Evidence that single nucleotide polymorphism in the uncoupling protein 3 (UCP3) gene influences fat distribution in women of European and Asian origin.
Diabetologia 2000;43(12):1558-64.
2000: S Jackson; S M Bagstaff; Stephen Lynn; Stephen J Yeaman; Douglass M Turnbull; Mark Walker
Decreased insulin responsiveness of glucose uptake in cultured human skeletal muscle cells from insulin-resistant nondiabetic relatives of type 2 diabetic families.
Diabetes 2000;49(7):1169-77.
2000: Mark E Daly; C Vale; Mark Walker; A Littlefield; K George; M Alberti; J Mathers
Acute fuel selection in response to high-sucrose and high-starch meals in healthy men.
The American journal of clinical nutrition 2000;71(6):1516-24.
2000: Mark Walker
Insulin resistance: a problem for clinicians and scientists.
Diabetic medicine : a journal of the British Diabetic Association 2000;17(5):406-8.
2000: Stephen Lynn; Andrew T Hattersley; Mark I McCarthy; Timothy M Frayling; Douglass M Turnbull; Mark Walker
Intermediate expansions of a X25/frataxin gene GAA repeat and type II diabetes: assessment using parent-offspring trios.
Diabetologia 2000;43(3):384-5.
2000: John P New; Rudy Bilous; Mark Walker
Insulin sensitivity in hypertensive Type 2 diabetic patients after 1 and 19 days' treatment with trandolapril.
Diabetic medicine : a journal of the British Diabetic Association 2000;17(2):134-40.
2000: Timothy M Frayling; Mark I McCarthy; Mark Walker; Jonathan C Levy; Stephen O'Rahilly; Graham A Hitman; PV Rao; A J Bennett; E C Jones; Stephan Menzel; Sian Ellard; Andrew T Hattersley
No evidence for linkage at candidate type 2 diabetes susceptibility loci on chromosomes 12 and 20 in United Kingdom Caucasians.
The Journal of clinical endocrinology and metabolism 2000;85(2):853-7.
2000: SJ Huxtable; PJ Saker; L Haddad; Mark Walker; Timothy M Frayling; Jonathan C Levy; Graham A Hitman; Stephen O'Rahilly; Andrew T Hattersley; Mark I McCarthy
Analysis of parent-offspring trios provides evidence for linkage and association between the insulin gene and type 2 diabetes mediated exclusively through paternally transmitted class III variable number tandem repeat alleles.
Diabetes 2000;49(1):126-30.
1999: Timothy M Frayling; Mark Walker; Mark I McCarthy; Julie C Evans; Lisa I S Allen; Stephen Lynn; S Ayres; B Millauer; C Turner; R C Turner; Mike J Sampson; Graham A Hitman; Sian Ellard; Andrew T Hattersley
Parent-offspring trios: a resource to facilitate the identification of type 2 diabetes genes.
Diabetes 1999;48(12):2475-9.
1999: Patrick F Chinnery; P J Zwijnenburg; Mark Walker; Neil Howell; R W Taylor; R N Lightowlers; Laurence A Bindoff; Douglass M Turnbull
Nonrandom tissue distribution of mutant mtDNA.
American journal of medical genetics 1999;85(5):498-501.
1998: Stephen Lynn; Theresa M Wardell; Margaret A Johnson; Patrick F Chinnery; Mark E Daly; Mark Walker; Douglass M Turnbull
Mitochondrial diabetes: investigation and identification of a novel mutation.
Diabetes 1998;47(11):1800-2.
1998: Murray W Stewart; David Humphriss; J Mitcheson; J Webster; Mark Walker; MF Laker
Lipoprotein composition and serum apolipoproteins in normoglycaemic first-degree relatives of non-insulin dependent diabetic patients.
Atherosclerosis 1998;139(1):115-21.
1998: Mark E Daly; C Vale; Mark Walker; A Littlefield; K G M M Alberti; John C Mathers
Acute effects on insulin sensitivity and diurnal metabolic profiles of a high-sucrose compared with a high-starch diet.
The American journal of clinical nutrition 1998;67(6):1186-96.
1998: Christopher P Day; J Grove; Ann K Daly; Murray W Stewart; Peter Avery; Mark Walker
Tumour necrosis factor-alpha gene promoter polymorphism and decreased insulin resistance.
Diabetologia 1998;41(4):430-4.
1998: K Kalidas; E Dow; PJ Saker; N Wareham; D Halsall; R S Jackson; S P Chan; S Gelding; Mark Walker; Eleni Kousta; Desmond G Johnston; Stephen O'Rahilly; Mark I McCarthy
Prohormone convertase 1 in obesity, gestational diabetes mellitus, and NIDDM: no evidence for a major susceptibility role.
Diabetes 1998;47(2):287-9.
1998: W Lowes; Mark Walker; K G Alberti; Loranne Agius
Hexokinase isoenzymes in normal and cirrhotic human liver: suppression of glucokinase in cirrhosis.
Biochimica et biophysica acta 1998;1379(1):134-42.
1997: Mark E Daly; C Vale; Mark Walker; K G M M Alberti; John C Mathers
Dietary carbohydrates and insulin sensitivity: a review of the evidence and clinical implications.
The American journal of clinical nutrition 1997;66(5):1072-85.
1997: David Humphriss; Murray W Stewart; T S Berrish; LA Barriocanal; L R Trajano; L A Ashworth; M D Brown; M Miller; Peter Avery; K G M M Alberti; Mark Walker
Multiple metabolic abnormalities in normal glucose tolerant relatives of NIDDM families.
Diabetologia 1997;40(10):1185-90.
1997: Mark Walker; T S Berrish; Murray W Stewart; David Humphriss; LA Barriocanal; K G M M Alberti
Metabolic heterogeneity in impaired glucose tolerance.
Metabolism: clinical and experimental 1997;46(8):914-7.
1997: J E Newkirk; R W Taylor; N Howell; Laurence A Bindoff; Patrick F Chinnery; K G M M Alberti; Douglass M Turnbull; Mark Walker
Maternally inherited diabetes and deafness: prevalence in a hospital diabetic population.
Diabetic medicine : a journal of the British Diabetic Association 1997;14(6):457-60.
1996: I Briceño; L A Barriocanal; Surinder S Papiha; L A Ashworth; A Gómez; J E Bernal; K G M M Alberti; Mark Walker
Lack of diabetes in rural Colombian Amerindians.
Diabetes care 1996;19(8):900-1.
1996: Murray W Stewart; J M Webster; David Humphriss; T Berrish; Mark Walker; MF Laker
Lipoprotein (a) concentrations and apolipoprotein (a) phenotypes in normoglycaemic relatives of type 2 diabetic patients.
Atherosclerosis 1996;124(1):119-24.
1996: M Armstrong; Faye Haldane; Peter Avery; J Mitcheson; Murray W Stewart; Douglass M Turnbull; Mark Walker
Relationship between insulin sensitivity and insulin receptor substrate-1 mutations in non-diabetic relatives of NIDDM families.
Diabetic medicine : a journal of the British Diabetic Association 1996;13(4):341-5.
1996: R W Taylor; R L Printz; M Armstrong; D K Granner; K G M M Alberti; D M Turnbull; Mark Walker
Variant sequences of the Hexokinase II gene in familial NIDDM.
Diabetologia 1996;39(3):322-8.
1996: M Armstrong; Faye Haldane; Robert W Taylor; David Humphriss; T Berrish; Murray W Stewart; Douglass M Turnbull; K G M M Alberti; Mark Walker
Human insulin receptor substrate-1: variant sequences in familial non-insulin-dependent diabetes mellitus.
Diabetic medicine : a journal of the British Diabetic Association 1996;13(2):133-8.
1995: Mark Walker; Robert W Taylor; Murray W Stewart; L A Bindoff; P A Shearing; V Anyaoku; M J Jackson; David Humphriss; D G Johnston; K G M M Alberti
Insulin and proinsulin secretion in subjects with abnormal glucose tolerance and a mitochondrial tRNA(Leu(UUR)) mutation.
Diabetes care 1995;18(11):1507-9.
1995: Mark Walker
Obesity, insulin resistance, and its link to non-insulin-dependent diabetes mellitus.
Metabolism: clinical and experimental 1995;44(9 Suppl 3):18-20.
1995: Murray W Stewart; David Humphriss; T S Berrish; L A Barriocanal; L R Trajano; K G M M Alberti; Mark Walker
Features of syndrome X in first-degree relatives of NIDDM patients.
Diabetes care 1995;18(7):1020-2.
1995: T S Berrish; C S Hetherington; K G M M Alberti; Mark Walker
Peripheral and hepatic insulin sensitivity in subjects with impaired glucose tolerance.
Diabetologia 1995;38(6):699-704.
1995: P Tong; T Thomas; T Berrish; David Humphriss; L Barriocanal; M Stewart; Mark Walker; Robert Wilkinson; K G M M Alberti
Cell membrane dynamics and insulin resistance in non-insulin-dependent diabetes mellitus.
Lancet 1995;345(8946):357-8.
1995: Mark Walker; Robert W Taylor; Murray W Stewart; L A Bindoff; M J Jackson; G K Alberti; Douglass M Turnbull
Insulin sensitivity and mitochondrial gene mutation.
Diabetes care 1995;18(2):273-5.
1994: R W Taylor; M W Stewart; Peter Avery; David Humphriss; K G M M Alberti; Douglass M Turnbull; Mark Walker
Apolipoprotein E and familial non-insulin-dependent diabetes mellitus.
Lancet 1994;344(8919):406.
1994: Mark Walker; T S Berrish; A R James; K G M M Alberti
Effect of hyperinsulinaemia on the function of the pituitary-adrenal axis in healthy man.
Clinical endocrinology 1994;40(4):493-7.
1994: Mark Walker; L R Trajano; K G M M Alberti; Pat Kendall-Taylor
Relapse of medically treated insulinoma following the development of thyrotoxicosis: an assessment of potential mechanisms.
Thyroid : official journal of the American Thyroid Association 1994;4(1):73-6.
1993: Y Bahru; P Kesteven; K G M M Alberti; Mark Walker
Decreased plasminogen activator inhibitor-1 activity in newly diagnosed type 2 diabetic patients following dietary modification.
Diabetic medicine : a journal of the British Diabetic Association 1993;10(9):802-6.
1993: Mark Walker; E Shmueli; S E Daley; B G Cooper; K G M M Alberti
Do nonesterified fatty acids regulate skeletal muscle protein turnover in humans?
The American journal of physiology 1993;265(3 Pt 1):E357-61.
1993: E Shmueli; Mark Walker; G Alberti; Christopher Oswold Record
Normal splanchnic but impaired peripheral insulin-stimulated glucose uptake in cirrhosis.
Hepatology (Baltimore, Md.) 1993;18(1):86-95.
1993: Mark Walker; Loranne Agius; H Orskov; K G M M Alberti
Peripheral and hepatic insulin sensitivity in non-insulin-dependent diabetes mellitus: effect of nonesterified fatty acids.
Metabolism: clinical and experimental 1993;42(5):601-8.
1993: G R Fulcher; Mark Walker; M Farrer; A S Johnson; K G M M Alberti
Acipimox increases glucose disposal in normal man independent of changes in plasma nonesterified fatty acid concentration and whole-body lipid oxidation rate.
Metabolism: clinical and experimental 1993;42(3):308-14.
1993: T S Berrish; C Elliott; B G Cooper; J W Reed; H Orskov; K G M M Alberti; Mark Walker
The role of plasma non-esterified fatty acids during exercise in type 2 diabetes mellitus.
Diabetic medicine : a journal of the British Diabetic Association 1993;10(2):152-8.
1993: Mark Walker; D Rodham; G R Fulcher; B Clayton; M Farrer; K G M M Alberti
Bioelectrical impedance and body composition.
Lancet 1993;341(8842):448.
1993: C Catalano; P H Winocour; Trevor H Thomas; Mark Walker; C F Sum; Robert Wilkinson; K G M M Alberti
Erythrocyte sodium-lithium countertransport activity and total body insulin-mediated glucose disposal in normoalbuminuric normotensive type 1 (insulin-dependent) diabetic patients.
Diabetologia 1993;36(1):52-6.
1992: G R Fulcher; C Catalano; Mark Walker; M Farrer; J Thow; C R Whately-Smith; K G M M Alberti
A double blind study of the effect of acipimox on serum lipids, blood glucose control and insulin action in non-obese patients with type 2 diabetes mellitus.
Diabetic medicine : a journal of the British Diabetic Association 1992;9(10):908-14.
1992: G R Fulcher; Mark Walker; C Catalano; Loranne Agius; K G M M Alberti
Metabolic effects of suppression of nonesterified fatty acid levels with acipimox in obese NIDDM subjects.
Diabetes 1992;41(11):1400-8.
1992: G R Fulcher; Mark Walker; C Catalano; M Farrer; K G M M Alberti
Acute metabolic and hormonal responses to the inhibition of lipolysis in non-obese patients with non-insulin-dependent (type 2) diabetes mellitus: effects of acipimox.
Clinical science (London, England : 1979) 1992;82(5):565-71.
1991: Mark Walker; G R Fulcher; H Marsiaj; H Orskov; K G M M Alberti
The independent effect of ketone bodies on forearm glucose metabolism in normal man.
Scandinavian journal of clinical and laboratory investigation 1991;51(7):605-13.
1991: Mark Walker; G R Fulcher; C F Sum; H Orskov; K G M M Alberti
Effect of glycemia and nonesterified fatty acids on forearm glucose uptake in normal humans.
The American journal of physiology 1991;261(3 Pt 1):E304-11.
1991: Mark Walker; B G Cooper; C Elliott; J W Reed; H Orskov; K G M M Alberti
Role of plasma non-esterified fatty acids during and after exercise.
Clinical science (London, England : 1979) 1991;81(3):319-25.
1991: G R Fulcher; M Farrer; Mark Walker; D Rodham; B Clayton; K M Alberti
A comparison of measurements of lean body mass derived by bioelectrical impedance, skinfold thickness and total body potassium. A study in obese and non-obese normal subjects.
Scandinavian journal of clinical and laboratory investigation 1991;51(3):245-53.
1990: Mark Walker; G R Fulcher; C Catalano; G Petranyi; H Orskov; K G M M Alberti
Physiological levels of plasma non-esterified fatty acids impair forearm glucose uptake in normal man.
Clinical science (London, England : 1979) 1990;79(2):167-74.