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Trevor Walker

Research Profile

Chemicals & Drugs

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TOP 3
Adriano G Rossi; Deborah A Sawatzky; Annemieke Walker; Carol Ward; Tara A Sheldrake; Nicola A Riley; Alison Caldicott; Magdalena Martinez-Losa; Trevor R Walker; Rodger Duffin; Mohini Gray; Elvira Crescenzi; Morag C Martin; Hugh J M Brady; John Savill; Ian Dransfield; Christopher Haslett
Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis.
Sarah R McMeekin; Ian Dransfield; Adriano G Rossi; Christopher Haslett; Trevor R Walker
E-selectin permits communication between PAF receptors and TRPC channels in human neutrophils.
Trevor R Walker; Karen A Cadwallader; Alison MacKinnon; Edwin R Chilvers
Thrombin induces DNA synthesis and phosphoinositide hydrolysis in airway smooth muscle by activation of distinct receptors.

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2006: Adriano G Rossi; Deborah A Sawatzky; Annemieke Walker; Carol Ward; Tara A Sheldrake; Nicola A Riley; Alison Caldicott; Magdalena Martinez-Losa; Trevor R Walker; Rodger Duffin; Mohini Gray; Elvira Crescenzi; Morag C Martin; Hugh J M Brady; John Savill; Ian Dransfield; Christopher Haslett
Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis.
Nature medicine 2006;12(9):1056-64.
2006: Sarah R McMeekin; Ian Dransfield; Adriano G Rossi; Christopher Haslett; Trevor R Walker
E-selectin permits communication between PAF receptors and TRPC channels in human neutrophils.
Blood 2006;107(12):4938-45.
2005: Trevor R Walker; Karen A Cadwallader; Alison MacKinnon; Edwin R Chilvers
Thrombin induces DNA synthesis and phosphoinositide hydrolysis in airway smooth muscle by activation of distinct receptors.
Biochemical pharmacology 2005;70(6):959-67.
2004: Trevor R Walker; Marie-Helene Ruchaud-Sparagano; Sarah R McMeekin; Ian Dransfield
A critical 'threshold' of beta 2-integrin engagement regulates augmentation of cytokine-mediated superoxide anion release.
British journal of pharmacology 2004;141(7):1131-40.
2002: Karen A Cadwallader; Alison M Condliffe; Alex McGregor; Trevor R Walker; Jessica F White; Len R Stephens; Edwin R Chilvers
Regulation of phosphatidylinositol 3-kinase activity and phosphatidylinositol 3,4,5-trisphosphate accumulation by neutrophil priming agents.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(6):3336-44.
2002: Alan Pemberton; Tatyana S Zamolodchikova; Cheryl L Scudamore; Edwin R Chilvers; Hugh Miller; Trevor R Walker
Proteolytic action of duodenase is required to induce DNA synthesis in pulmonary artery fibroblasts.
European journal of biochemistry / FEBS 2002;269(4):1171-80.
2000: Stuart J Hirst; Trevor R Walker; Edwin R Chilvers
Phenotypic diversity and molecular mechanisms of airway smooth muscle proliferation in asthma.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2000;16(1):159-77.
2000: Marie-Helene Ruchaud-Sparagano; Trevor R Walker; Adriano G Rossi; Christopher Haslett; Ian Dransfield
Soluble E-selectin acts in synergy with platelet-activating factor to activate neutrophil beta 2-integrins. Role of tyrosine kinases and Ca2+ mobilization.
The Journal of biological chemistry 2000;275(21):15758-64.
2000: Alison M Condliffe; Karen A Cadwallader; Trevor R Walker; Robert C Rintoul; Andrew S Cowburn; Edwin R Chilvers
Phosphoinositide 3-kinase: a critical signalling event in pulmonary cells.
Respiratory research 2000;1(1):24-9.
1999: Vera P Krymskaya; Raymond B Penn; MJ Orsini; P H Scott; Robin Plevin; Trevor R Walker; Andrew Eszterhas; Yassine Amrani; Edwin R Chilvers; Reynold A Panettieri
Phosphatidylinositol 3-kinase mediates mitogen-induced human airway smooth muscle cell proliferation.
The American journal of physiology 1999;277(1 Pt 1):L65-78.
1998: Trevor R Walker; SM Moore; MF Lawson; Reynold A Panettieri; Edwin R Chilvers
Platelet-derived growth factor-BB and thrombin activate phosphoinositide 3-kinase and protein kinase B: role in mediating airway smooth muscle proliferation.
Molecular pharmacology 1998;54(6):1007-15.
1998: SM Moore; Robert C Rintoul; Trevor R Walker; Edwin R Chilvers; Christopher Haslett; Tariq Sethi
The presence of a constitutively active phosphoinositide 3-kinase in small cell lung cancer cells mediates anchorage-independent proliferation via a protein kinase B and p70s6k-dependent pathway.
Cancer research 1998;58(22):5239-47.
1997: B J Lynch; M M Muqit; Trevor R Walker; Edwin R Chilvers
[3H]inositol polyphosphate metabolism in muscarinic cholinoceptor-stimulated airways smooth muscle: accumulation of [3H]inositol 4,5 bisphosphate via a lithium-sensitive inositol polyphosphate 1-phosphatase.
The Journal of pharmacology and experimental therapeutics 1997;280(2):974-82.