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John Wallace
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39
McKnight, Webb
33
Cirino, Giuseppe
29
Fiorucci, Stefano
23
MacNaughton, Wallace
20
Vergnolle, Nathalie
19
Hollenberg, Morley
18
Del Soldato, Piero
15
Mencarelli, Andrea
14
Sharkey, Keith
13
Distrutti, Eleonora
12
Dicay, Michael
11
Befus, Dean
11
Morelli, Antonio
10
Muscará, Marcelo
10
McCafferty, Donna-Marie
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All Publications
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2009: Wallace John L; Vong Linda; McKnight Webb; Dicay Michael; Martin Gary R
Endogenous and exogenous hydrogen sulfide promotes resolution of colitis in rats.
Gastroenterology 2009;137(2):569-78, 578.e1.
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2009: McKay Derek M; Wallace John L
Acetic acid induced ulceration in rats is not affected by infection with Hymenolepis diminuta.
The Journal of parasitology 2009;95(2):481-2.
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2008: Wallace John L; Vong Linda
NSAID-induced gastrointestinal damage and the design of GI-sparing NSAIDs.
Current opinion in investigational drugs (London, England : 2000) 2008;9(11):1151-6.
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2008: Chávez-Piña A E; Vong L; McKnight W; Dicay M; Zanardo R C O; Ortiz M I; Castañeda-Hernández G; Wallace J L
Lack of effects of acemetacin on signalling pathways for leukocyte adherence may explain its gastrointestinal safety.
British journal of pharmacology 2008;155(6):857-64.
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2008: Martin Gary R; Perretti Mauro; Flower Roderick J; Wallace John L
Annexin-1 modulates repair of gastric mucosal injury.
American journal of physiology. Gastrointestinal and liver physiology 2008;294(3):G764-9.
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2007: Wallace John L; Dicay Michael; McKnight Webb; Martin Gary R
Hydrogen sulfide enhances ulcer healing in rats.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(14):4070-6.
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2007: Chávez-Piña A E; McKnight W; Dicay M; Castañeda-Hernández G; Wallace J L
Mechanisms underlying the anti-inflammatory activity and gastric safety of acemetacin.
British journal of pharmacology 2007;152(6):930-8.
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2007: Wallace John L
Hydrogen sulfide-releasing anti-inflammatory drugs.
Trends in pharmacological sciences 2007;28(10):501-5.
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2007: Wallace J L
Building a better aspirin: gaseous solutions to a century-old problem.
British journal of pharmacology 2007;152(4):421-8.
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2007: Fiorucci S; Orlandi S; Mencarelli A; Caliendo G; Santagada V; Distrutti E; Santucci L; Cirino G; Wallace J L
Enhanced activity of a hydrogen sulphide-releasing derivative of mesalamine (ATB-429) in a mouse model of colitis.
British journal of pharmacology 2007;150(8):996-1002.
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2007: Moreira Vanessa; Zamuner Stella Regina; Wallace John L; Teixeira Catarina de Fátima Pereira
Bothrops jararaca and Crotalus durissus terrificus venoms elicit distinct responses regarding to production of prostaglandins E2 and D2, and expression of cyclooxygenases.
Toxicon : official journal of the International Society on Toxinology 2007;49(5):615-24.
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2007: Olivo Renata do A; Teixeira Catarina F P; Wallace John L; Gutierrez Jose M; Zamuner Stella R
Role of cyclooxygenases in oedema-forming activity of bothropic venoms.
Toxicon : official journal of the International Society on Toxinology 2007;49(5):670-7.
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2007: Wallace John L; Caliendo Giuseppe; Santagada Vincenzo; Cirino Giuseppe; Fiorucci Stefano
Gastrointestinal safety and anti-inflammatory effects of a hydrogen sulfide-releasing diclofenac derivative in the rat.
Gastroenterology 2007;132(1):261-71.
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2006: Skinn Andrew C; Vergnolle Nathalie; Zamuner Stella R; Wallace John L; Cellars Laurie; MacNaughton Wallace K; Sherman Philip M
Citrobacter rodentium infection causes iNOS-independent intestinal epithelial dysfunction in mice.
Canadian journal of physiology and pharmacology 2006;84(12):1301-12.
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2006: Zanardo Renata C O; Brancaleone Vincenzo; Distrutti Eleonora; Fiorucci Stefano; Cirino Giuseppe; Wallace John L
Hydrogen sulfide is an endogenous modulator of leukocyte-mediated inflammation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(12):2118-20.
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2006: Distrutti Eleonora; Sediari Luca; Mencarelli Andrea; Renga Barbara; Orlandi Stefano; Russo Giuseppe; Caliendo Giuseppe; Santagada Vincenzo; Cirino Giuseppe; Wallace John L; Fiorucci Stefano
5-Amino-2-hydroxybenzoic acid 4-(5-thioxo-5H-[1,2]dithiol-3yl)-phenyl ester (ATB-429), a hydrogen sulfide-releasing derivative of mesalamine, exerts antinociceptive effects in a model of postinflammatory hypersensitivity.
The Journal of pharmacology and experimental therapeutics 2006;319(1):447-58.
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2006: Vergnolle Nathalie; Cellars Laurie; Mencarelli Andrea; Rizzo Giovanni; Swaminathan Sunita; Beck Paul; Steinhoff Martin; Andrade-Gordon Patricia; Bunnett Nigel W; Hollenberg Morley D; Wallace John L; Cirino Giuseppe; Fiorucci Stefano
A role for proteinase-activated receptor-1 in inflammatory bowel diseases.
The Journal of clinical investigation 2006;116(7):2056.
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2006: Fiorucci Stefano; Distrutti Eleonora; Cirino Giuseppe; Wallace John L
The emerging roles of hydrogen sulfide in the gastrointestinal tract and liver.
Gastroenterology 2006;131(1):259-71.
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2006: Wallace John L; Dicay Michael; McKnight Webb; Dudar Genevieve K
Platelets accelerate gastric ulcer healing through presentation of vascular endothelial growth factor.
British journal of pharmacology 2006;148(3):274-8.
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2006: Wallace John L
Nitric oxide, aspirin-triggered lipoxins and NO-aspirin in gastric protection.
Inflammation & allergy drug targets 2006;5(2):133-7.
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2006: Muscará Marcelo N; Wallace John L
COX-inhibiting nitric oxide donors (CINODs): potential benefits on cardiovascular and renal function.
Cardiovascular & hematological agents in medicinal chemistry 2006;4(2):155-64.
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2006: Wallace John L
Commonality of defensive roles of COX-2 in the lung and gut.
The American journal of pathology 2006;168(4):1060-3.
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2006: Martin Gary R; Wallace John L
Gastrointestinal inflammation: a central component of mucosal defense and repair.
Experimental biology and medicine (Maywood, N.J.) 2006;231(2):130-7.
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2006: Distrutti Eleonora; Sediari Luca; Mencarelli Andrea; Renga Barbara; Orlandi Stefano; Antonelli Elisabetta; Roviezzo Fiorenza; Morelli Antonio; Cirino Giuseppe; Wallace John L; Fiorucci Stefano
Evidence that hydrogen sulfide exerts antinociceptive effects in the gastrointestinal tract by activating KATP channels.
The Journal of pharmacology and experimental therapeutics 2006;316(1):325-35.
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2006: Wallace John L
COX-2: a pivotal enzyme in mucosal protection and resolution of inflammation.
TheScientificWorldJournal 2006;6():577-88.
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2005: Wallace John L
Recent advances in gastric ulcer therapeutics.
Current opinion in pharmacology 2005;5(6):573-7.
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2005: Zamuner Stella R; Bak Adrian W; Devchand Pallavi R; Wallace John L
Predisposition to colorectal cancer in rats with resolved colitis: role of cyclooxygenase-2-derived prostaglandin d2.
The American journal of pathology 2005;167(5):1293-300.
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2005: Fiorucci Stefano; Antonelli Elisabetta; Distrutti Eleonora; Rizzo Giovanni; Mencarelli Andrea; Orlandi Stefano; Zanardo Renata; Renga Barbara; Di Sante Moses; Morelli Antonio; Cirino Giuseppe; Wallace John L
Inhibition of hydrogen sulfide generation contributes to gastric injury caused by anti-inflammatory nonsteroidal drugs.
Gastroenterology 2005;129(4):1210-24.
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2005: Perini Rafael; Wallace John L; Ma Li
Roles of platelets and proteinase-activated receptors in gastric ulcer healing.
Digestive diseases and sciences 2005;50 Suppl 1():S12-5.
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2005: Santos Camila L; Souza Marcellus H L P; Gomes Antoniella S; Lemos Henrique P; Santos Armênio A; Cunha Fernando Q; Wallace John L
Sildenafil prevents indomethacin-induced gastropathy in rats: role of leukocyte adherence and gastric blood flow.
British journal of pharmacology 2005;146(4):481-6.
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2005: Cenac Nicolas; Cellars Laurie; Steinhoff Martin; Andrade-Gordon Patricia; Hollenberg Morley Donald; Wallace John Lawrence; Fiorucci Stefano; Vergnolle Nathalie
Proteinase-activated receptor-1 is an anti-inflammatory signal for colitis mediated by a type 2 immune response.
Inflammatory bowel diseases 2005;11(9):792-8.
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2005: Wallace John L; de Lima Octavio Menezes; Fiorucci Stefano
Lipoxins in gastric mucosal health and disease.
Prostaglandins, leukotrienes, and essential fatty acids 2005;73(3-4):251-5.
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2005: Hansen Kristina K; Sherman Philip M; Cellars Laurie; Andrade-Gordon Patricia; Pan Zhengying; Baruch Amos; Wallace John L; Hollenberg Morley D; Vergnolle Nathalie
A major role for proteolytic activity and proteinase-activated receptor-2 in the pathogenesis of infectious colitis.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(23):8363-8.
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2005: Wallace John L; Devchand Pallavi R
Emerging roles for cyclooxygenase-2 in gastrointestinal mucosal defense.
British journal of pharmacology 2005;145(3):275-82.
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2005: Chou May M; Vergnolle Nathalie; McDougall Jason J; Wallace John L; Marty Stephanie; Teskey Val; Buret Andre G
Effects of chondroitin and glucosamine sulfate in a dietary bar formulation on inflammation, interleukin-1beta, matrix metalloprotease-9, and cartilage damage in arthritis.
Experimental biology and medicine (Maywood, N.J.) 2005;230(4):255-62.
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2005: Wallace John L
Nitric oxide as a regulator of inflammatory processes.
Memórias do Instituto Oswaldo Cruz 2005;100 Suppl 1():5-9.
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2005: Zanardo Renata C O; Perretti Mauro; Wallace John L
Annexin-1 is an endogenous gastroprotective factor against indomethacin-induced damage.
American journal of physiology. Gastrointestinal and liver physiology 2005;288(3):G481-6.
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2005: Ma Li; Perini Rafael; McKnight Webb; Dicay Michael; Klein Andre; Hollenberg Morley D; Wallace John L
Proteinase-activated receptors 1 and 4 counter-regulate endostatin and VEGF release from human platelets.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(1):216-20.
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2004: Vergnolle Nathalie; Cellars Laurie; Mencarelli Andrea; Rizzo Giovanni; Swaminathan Sunita; Beck Paul; Steinhoff Martin; Andrade-Gordon Patricia; Bunnett Nigel W; Hollenberg Morley D; Wallace John L; Cirino Giuseppe; Fiorucci Stefano
A role for proteinase-activated receptor-1 in inflammatory bowel diseases.
The Journal of clinical investigation 2004;114(10):1444-56.
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2004: Fiorucci Stefano; Wallace John L; Mencarelli Andrea; Distrutti Eleonora; Rizzo Giovanni; Farneti Silvana; Morelli Antonio; Tseng Jih-Lie; Suramanyam Babu; Guilford William J; Parkinson John F
A beta-oxidation-resistant lipoxin A4 analog treats hapten-induced colitis by attenuating inflammation and immune dysfunction.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(44):15736-41.
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2004: Hyun Eric; Bolla Manlio; Steinhoff Martin; Wallace John L; Soldato Piero Del; Vergnolle Nathalie
Anti-inflammatory effects of nitric oxide-releasing hydrocortisone NCX 1022, in a murine model of contact dermatitis.
British journal of pharmacology 2004;143(5):618-25.
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2004: Antony Joseph M; van Marle Guido; Opii Wycliffe; Butterfield D Allan; Mallet François; Yong Voon Wee; Wallace John L; Deacon Robert M; Warren Kenneth; Power Christopher
Human endogenous retrovirus glycoprotein-mediated induction of redox reactants causes oligodendrocyte death and demyelination.
Nature neuroscience 2004;7(10):1088-95.
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2004: Wallace John L
Acetaminophen hepatotoxicity: NO to the rescue.
British journal of pharmacology 2004;143(1):1-2.
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2004: von der Weid Pierre-Yves; Hollenberg Morley D; Fiorucci Stefano; Wallace John L
Aspirin-triggered, cyclooxygenase-2-dependent lipoxin synthesis modulates vascular tone.
Circulation 2004;110(10):1320-5.
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2004: Wallace John L; Rizzo Gianni; Cirino Giuseppe; Del Soldato Piero; Fiorucci Stefano
Enhanced anti-inflammatory potency of a nitric oxide-releasing derivative of flunisolide: role of nuclear factor-kappaB.
The Journal of pharmacology and experimental therapeutics 2004;310(3):1096-102.
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2004: Alshurafa Hashem N; Stenton Grant R; Wallace John L; Hollenberg Morley D; Befus A Dean; Vliagoftis Harissios
A protease activated receptor-2 (PAR-2) activating peptide, tc-LIGRLO-NH2, induces protease release from mast cells: role in TNF degradation.
BMC pharmacology 2004;4():12.
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2004: Fiorucci Stefano; Distrutti Eleonora; Mencarelli Andrea; Rizzo Giovanni; Lorenzo Anna Rita Di; Baldoni Monia; Del Soldato Piero; Morelli Antonio; Wallace John L
Cooperation between aspirin-triggered lipoxin and nitric oxide (NO) mediates antiadhesive properties of 2-(Acetyloxy)benzoic acid 3-(nitrooxymethyl)phenyl ester (NCX-4016) (NO-aspirin) on neutrophil-endothelial cell adherence.
The Journal of pharmacology and experimental therapeutics 2004;309(3):1174-82.
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2004: Wallace John L; Muscará Marcelo N; de Nucci Gilberto; Zamuner Stella; Cirino Giuseppe; del Soldato Piero; Ongini Ennio
Gastric tolerability and prolonged prostaglandin inhibition in the brain with a nitric oxide-releasing flurbiprofen derivative, NCX-2216 [3-[4-(2-fluoro-alpha-methyl-[1,1'-biphenyl]-4-acetyloxy)-3-methoxyphenyl]-2-propenoic acid 4-nitrooxy butyl ester].
The Journal of pharmacology and experimental therapeutics 2004;309(2):626-33.
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2004: Perini Rafael; Fiorucci Stefano; Wallace John L
Mechanisms of nonsteroidal anti-inflammatory drug-induced gastrointestinal injury and repair: a window of opportunity for cyclooxygenase-inhibiting nitric oxide donors.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 2004;18(4):229-36.
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2004: Wallace John L; Zamuner Stella R; McKnight Webb; Dicay Michael; Mencarelli Andrea; del Soldato Piero; Fiorucci Stefano
Aspirin, but not NO-releasing aspirin (NCX-4016), interacts with selective COX-2 inhibitors to aggravate gastric damage and inflammation.
American journal of physiology. Gastrointestinal and liver physiology 2004;286(1):G76-81.
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2003: Zamuner S R; Warrier N; Buret A G; MacNaughton W K; Wallace J L
Cyclooxygenase 2 mediates post-inflammatory colonic secretory and barrier dysfunction.
Gut 2003;52(12):1714-20.
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2003: Nguyen Cathy; Coelho Anne-Marie; Grady Eileen; Compton Steven J; Wallace John L; Hollenberg Morley D; Cenac Nicolas; Garcia-Villar Rafael; Bueno Lionel; Steinhoff Martin; Bunnett Nigel W; Vergnolle Nathalie
Colitis induced by proteinase-activated receptor-2 agonists is mediated by a neurogenic mechanism.
Canadian journal of physiology and pharmacology 2003;81(9):920-7.
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2003: Chin Alex C; Vergnolle Nathalie; MacNaughton Wallace K; Wallace John L; Hollenberg Morley D; Buret Andre G
Proteinase-activated receptor 1 activation induces epithelial apoptosis and increases intestinal permeability.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(19):11104-9.
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2003: Fiorucci Stefano; Santucci Luca; Wallace John L; Sardina Marco; Romano Mario; del Soldato Piero; Morelli Antonio
Interaction of a selective cyclooxygenase-2 inhibitor with aspirin and NO-releasing aspirin in the human gastric mucosa.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(19):10937-41.
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2003: Fiorucci Stefano; Distrutti Eleonora; Mencarelli Andrea; Morelli Antonio; Laufor Stefan A; Cirino Giuseppe; Wallace John L
Evidence that 5-lipoxygenase and acetylated cyclooxygenase 2-derived eicosanoids regulate leukocyte-endothelial adherence in response to aspirin.
British journal of pharmacology 2003;139(7):1351-9.
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2003: Wallace John L; Fiorucci Stefano
A magic bullet for mucosal protection...and aspirin is the trigger!
Trends in pharmacological sciences 2003;24(7):323-6.
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2003: Turesin Fusun; del Soldato Piero; Wallace John L
Enhanced anti-inflammatory potency of a nitric oxide-releasing prednisolone derivative in the rat.
British journal of pharmacology 2003;139(5):966-72.
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2003: Souza Marcellus H L P; de Lima Octavio Menezes; Zamuner Stella R; Fiorucci Stefano; Wallace John L
Gastritis increases resistance to aspirin-induced mucosal injury via COX-2-mediated lipoxin synthesis.
American journal of physiology. Gastrointestinal and liver physiology 2003;285(1):G54-61.
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2003: Fiorucci Stefano; Distrutti Eleonora; de Lima Octavio Menezes; Romano Mario; Mencarelli Andrea; Barbanti Miriam; Palazzini Ernesto; Morelli Antonio; Wallace John L
Relative contribution of acetylated cyclo-oxygenase (COX)-2 and 5-lipooxygenase (LOX) in regulating gastric mucosal integrity and adaptation to aspirin.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(9):1171-3.
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2003: Wallace J L
Nitric oxide-releasing mesalamine: potential utility for treatment of inflammatory bowel disease.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2003;35 Suppl 2():S35-40.
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2003: Thomson A B R; Appleman S; Keelan M; Wallace J L
Role of gastric mucosal and gastric juice cytokine concentrations in development of bisphosphonate damage to gastric mucosa.
Digestive diseases and sciences 2003;48(2):308-14.
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2003: Wallace John L; Del Soldato Piero
The therapeutic potential of NO-NSAIDs.
Fundamental & clinical pharmacology 2003;17(1):11-20.
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2003: Perini Rafael F; Ma Li; Wallace John L
Mucosal repair and COX-2 inhibition.
Current pharmaceutical design 2003;9(27):2207-11.
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2002: Cenac Nicolas; Coelho Anne-Marie; Nguyen Cathy; Compton Steven; Andrade-Gordon Patricia; MacNaughton Wallace K; Wallace John L; Hollenberg Morley D; Bunnett Nigel W; Garcia-Villar Rafael; Bueno Lionel; Vergnolle Nathalie
Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2.
The American journal of pathology 2002;161(5):1903-15.
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2002: Fiorucci Stefano; de Lima Octavio Menezes; Mencarelli Andrea; Palazzetti Barbara; Distrutti Eleonora; McKnight Webb; Dicay Michael; Ma Li; Romano Mario; Morelli Antonio; Wallace John L
Cyclooxygenase-2-derived lipoxin A4 increases gastric resistance to aspirin-induced damage.
Gastroenterology 2002;123(5):1598-606.
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2002: Ma Li; del Soldato Piero; Wallace John L
Divergent effects of new cyclooxygenase inhibitors on gastric ulcer healing: Shifting the angiogenic balance.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(20):13243-7.
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2002: Stenton Grant R; Nohara Osamu; Déry René E; Vliagoftis Harissios; Gilchrist Mark; Johri Ankur; Wallace John L; Hollenberg Morley D; Moqbel Redwan; Befus A Dean
Proteinase-activated receptor (PAR)-1 and -2 agonists induce mediator release from mast cells by pathways distinct from PAR-1 and PAR-2.
The Journal of pharmacology and experimental therapeutics 2002;302(2):466-74.
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2002: Wallace John L; Ignarro Louis J; Fiorucci Stefano
Potential cardioprotective actions of no-releasing aspirin.
Nature reviews. Drug discovery 2002;1(5):375-82.
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2002: Gilchrist Mark; Savoie Michelle; Nohara Osamu; Wills Fiona L; Wallace John L; Befus A D
Nitric oxide synthase and nitric oxide production in in vivo-derived mast cells.
Journal of leukocyte biology 2002;71(4):618-24.
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2002: Rossoni Giuseppe; Muscara Marcelo N; Cirino Giuseppe; Wallace John L
Inhibition of cyclo-oxygenase-2 exacerbates ischaemia-induced acute myocardial dysfunction in the rabbit.
British journal of pharmacology 2002;135(6):1540-6.
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2002: Fiorucci Stefano; Antonelli Elisabetta; Mencarelli Andrea; Palazzetti Barbara; Alvarez-Miller Lorena; Muscara Marcelo; del Soldato Piero; Sanpaolo Laura; Wallace John L; Morelli Antonio
A NO-releasing derivative of acetaminophen spares the liver by acting at several checkpoints in the Fas pathway.
British journal of pharmacology 2002;135(3):589-99.
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2001: Wallace J L; Muscará M N
Selective cyclo-oxygenase-2 inhibitors: cardiovascular and gastrointestinal toxicity.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2001;33 Suppl 2():S21-8.
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2001: Wallace J L; Ma L
Inflammatory mediators in gastrointestinal defense and injury.
Experimental biology and medicine (Maywood, N.J.) 2001;226(11):1003-15.
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2001: Fiorucci S; Mencarelli A; Palazzetti B; Distrutti E; Vergnolle N; Hollenberg M D; Wallace J L; Morelli A; Cirino G
Proteinase-activated receptor 2 is an anti-inflammatory signal for colonic lamina propria lymphocytes in a mouse model of colitis.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(24):13936-41.
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2001: Ma L; Hollenberg M D; Wallace J L
Thrombin-induced platelet endostatin release is blocked by a proteinase activated receptor-4 (PAR4) antagonist.
British journal of pharmacology 2001;134(4):701-4.
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2001: Wallace J L
Pathogenesis of NSAID-induced gastroduodenal mucosal injury.
Best practice & research. Clinical gastroenterology 2001;15(5):691-703.
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2001: Fiorucci S; Distrutti E; Ajuebor M N; Mencarelli A; Mannucci R; Palazzetti B; Del Soldato P; Morelli A; Wallace J L
NO-mesalamine protects colonic epithelial cells against apoptotic damage induced by proinflammatory cytokines.
American journal of physiology. Gastrointestinal and liver physiology 2001;281(3):G654-65.
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2001: Asfaha S; MacNaughton W K; Appleyard C B; Chadee K; Wallace J L
Persistent epithelial dysfunction and bacterial translocation after resolution of intestinal inflammation.
American journal of physiology. Gastrointestinal and liver physiology 2001;281(3):G635-44.
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2001: Muscará M N; Lovren F; McKnight W; Dicay M; del Soldato P; Triggle C R; Wallace J L
Vasorelaxant effects of a nitric oxide-releasing aspirin derivative in normotensive and hypertensive rats.
British journal of pharmacology 2001;133(8):1314-22.
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2001: Buresi M C; Schleihauf E; Vergnolle N; Buret A; Wallace J L; Hollenberg M D; MacNaughton W K
Protease-activated receptor-1 stimulates Ca(2+)-dependent Cl(-) secretion in human intestinal epithelial cells.
American journal of physiology. Gastrointestinal and liver physiology 2001;281(2):G323-32.
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2001: Vergnolle N; Bunnett N W; Sharkey K A; Brussee V; Compton S J; Grady E F; Cirino G; Gerard N; Basbaum A I; Andrade-Gordon P; Hollenberg M D; Wallace J L
Proteinase-activated receptor-2 and hyperalgesia: A novel pain pathway.
Nature medicine 2001;7(7):821-6.
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2001: Ma L; Elliott S N; Cirino G; Buret A; Ignarro L J; Wallace J L
Platelets modulate gastric ulcer healing: role of endostatin and vascular endothelial growth factor release.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(11):6470-5.
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2001: Vergnolle N; Wallace J L; Bunnett N W; Hollenberg M D
Protease-activated receptors in inflammation, neuronal signaling and pain.
Trends in pharmacological sciences 2001;22(3):146-52.
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2001: Wallace J L
Nonsteroidal anti-inflammatory drugs and the gastrointestinal tract. Mechanisms of protection and healing: current knowledge and future research.
The American journal of medicine 2001;110(1A):19S-23S.
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2001: Ajuebor M N; Hogaboam C M; Kunkel S L; Proudfoot A E; Wallace J L
The chemokine RANTES is a crucial mediator of the progression from acute to chronic colitis in the rat.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(1):552-8.
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2000: Barnett K; Bell C J; McKnight W; Dicay M; Sharkey K A; Wallace J L
Role of cyclooxygenase-2 in modulating gastric acid secretion in the normal and inflamed rat stomach.
American journal of physiology. Gastrointestinal and liver physiology 2000;279(6):G1292-7.
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2000: Vliagoftis H; Schwingshackl A; Milne C D; Duszyk M; Hollenberg M D; Wallace J L; Befus A D; Moqbel R
Proteinase-activated receptor-2-mediated matrix metalloproteinase-9 release from airway epithelial cells.
The Journal of allergy and clinical immunology 2000;106(3):537-45.
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2000: Wallace J L; McKnight W; Reuter B K; Vergnolle N
NSAID-induced gastric damage in rats: requirement for inhibition of both cyclooxygenase 1 and 2.
Gastroenterology 2000;119(3):706-14.
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2000: Wallace J L; Miller M J
Nitric oxide in mucosal defense: a little goes a long way.
Gastroenterology 2000;119(2):512-20.
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2000: Muscará M N; McKnight W; Lovren F; Triggle C R; Cirino G; Wallace J L
Antihypertensive properties of a nitric oxide-releasing naproxen derivative in two-kidney, one-clip rats.
American journal of physiology. Heart and circulatory physiology 2000;279(2):H528-35.
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2000: Ma L; Wallace J L
Endothelial nitric oxide synthase modulates gastric ulcer healing in rats.
American journal of physiology. Gastrointestinal and liver physiology 2000;279(2):G341-6.
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2000: Cicala C; Ianaro A; Fiorucci S; Calignano A; Bucci M; Gerli R; Santucci L; Wallace J L; Cirino G
NO-naproxen modulates inflammation, nociception and downregulates T cell response in rat Freund's adjuvant arthritis.
British journal of pharmacology 2000;130(6):1399-405.
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2000: Ajuebor M N; Singh A; Wallace J L
Cyclooxygenase-2-derived prostaglandin D(2) is an early anti-inflammatory signal in experimental colitis.
American journal of physiology. Gastrointestinal and liver physiology 2000;279(1):G238-44.
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2000: McCafferty D M; Sihota E; Muscara M; Wallace J L; Sharkey K A; Kubes P
Spontaneously developing chronic colitis in IL-10/iNOS double-deficient mice.
American journal of physiology. Gastrointestinal and liver physiology 2000;279(1):G90-9.
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2000: Muscará M N; Vergnolle N; Lovren F; Triggle C R; Elliott S N; Asfaha S; Wallace J L
Selective cyclo-oxygenase-2 inhibition with celecoxib elevates blood pressure and promotes leukocyte adherence.
British journal of pharmacology 2000;129(7):1423-30.
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2000: Wallace J L
How do NSAIDs cause ulcer disease?
Baillière's best practice & research. Clinical gastroenterology 2000;14(1):147-59.
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2000: Muscará M N; McKnight W; Asfaha S; Wallace J L
Wound collagen deposition in rats: effects of an NO-NSAID and a selective COX-2 inhibitor.
British journal of pharmacology 2000;129(4):681-6.
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2000: Elliott S N; Wallace J L; McKnight W; Gall D G; Hardin J A; Olson M; Buret A
Bacterial colonization and healing of gastric ulcers: the effects of epidermal growth factor.
American journal of physiology. Gastrointestinal and liver physiology 2000;278(1):G105-12.
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1999: Wallace J L
Distribution and expression of cyclooxygenase (COX) isoenzymes, their physiological roles, and the categorization of nonsteroidal anti-inflammatory drugs (NSAIDs).
The American journal of medicine 1999;107(6A):11S-16S; discussion 16S-17S.
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1999: Wallace J L; Dicay M; McKnight W; Bastaki S; Blank M A
N-bisphosphonates cause gastric epithelial injury independent of effects on the microcirculation.
Alimentary pharmacology & therapeutics 1999;13(12):1675-82.
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1999: Reuter B K; Wallace J L
Phosphodiesterase inhibitors prevent NSAID enteropathy independently of effects on TNF-alpha release.
The American journal of physiology 1999;277(4 Pt 1):G847-54.
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1999: Wallace J L; Vergnolle N; Muscará M N; Asfaha S; Chapman K; McKnight W; Del Soldato P; Morelli A; Fiorucci S
Enhanced anti-inflammatory effects of a nitric oxide-releasing derivative of mesalamine in rats.
Gastroenterology 1999;117(3):557-66.
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1999: Vergnolle N; Hollenberg M D; Sharkey K A; Wallace J L
Characterization of the inflammatory response to proteinase-activated receptor-2 (PAR2)-activating peptides in the rat paw.
British journal of pharmacology 1999;127(5):1083-90.
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1999: Muscará M N; Wallace J L
Nitric Oxide. V. therapeutic potential of nitric oxide donors and inhibitors.
The American journal of physiology 1999;276(6 Pt 1):G1313-6.
-
1999: Vergnolle N; Hollenberg M D; Wallace J L
Pro- and anti-inflammatory actions of thrombin: a distinct role for proteinase-activated receptor-1 (PAR1).
British journal of pharmacology 1999;126(5):1262-8.
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1999: Wallace J L; Chapman K; McKnight W
Limited anti-inflammatory efficacy of cyclo-oxygenase-2 inhibition in carrageenan-airpouch inflammation.
British journal of pharmacology 1999;126(5):1200-4.
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1999: Bastaki S M; Wallace J L
Pathogenesis of nonsteroidal anti-inflammatory drug gastropathy: clues to preventative therapy.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 1999;13(2):123-7.
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1999: Asfaha S; Bell C J; Wallace J L; MacNaughton W K
Prolonged colonic epithelial hyporesponsiveness after colitis: role of inducible nitric oxide synthase.
The American journal of physiology 1999;276(3 Pt 1):G703-10.
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1999: Wallace J L
Selective COX-2 inhibitors: is the water becoming muddy?
Trends in pharmacological sciences 1999;20(1):4-6.
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1999: Wallace J L; Muscara M N; McKnight W; Dicay M; Del Soldato P; Cirino G
In vivo antithrombotic effects of a nitric oxide-releasing aspirin derivative, NCX-4016.
Thrombosis research 1999;93(1):43-50.
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1998: Elliott S N; Wallace J L
Nitric oxide: a regulator of mucosal defense and injury.
Journal of gastroenterology 1998;33(6):792-803.
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1998: Elliott S N; Wallace J L
Neutrophil-mediated gastrointestinal injury.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 1998;12(8):559-68.
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1998: Elliott S N; Buret A; McKnight W; Miller M J; Wallace J L
Bacteria rapidly colonize and modulate healing of gastric ulcers in rats.
The American journal of physiology 1998;275(3 Pt 1):G425-32.
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1998: Wallace J L; Bak A; McKnight W; Asfaha S; Sharkey K A; MacNaughton W K
Cyclooxygenase 1 contributes to inflammatory responses in rats and mice: implications for gastrointestinal toxicity.
Gastroenterology 1998;115(1):101-9.
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1998: Vergnolle N; Macnaughton W K; Al-Ani B; Saifeddine M; Wallace J L; Hollenberg M D
Proteinase-activated receptor 2 (PAR2)-activating peptides: identification of a receptor distinct from PAR2 that regulates intestinal transport.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(13):7766-71.
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1998: Wallace J L; McKnight W; Asfaha S; Liu D Y
Reduction of acute and reactivated colitis in rats by an inhibitor of neutrophil activation.
The American journal of physiology 1998;274(5 Pt 1):G802-8.
-
1998: Miampamba M; Parr E J; McCafferty D M; Wallace J L; Sharkey K A
Effect of intracolonic benzalkonium chloride on trinitrobenzene sulphonic acid-induced colitis in the rat.
Alimentary pharmacology & therapeutics 1998;12(3):219-28.
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1998: Wallace J L; McCafferty D M; Sharkey K A
Lack of beneficial effect of a tachykinin receptor antagonist in experimental colitis.
Regulatory peptides 1998;73(2):95-101.
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1998: Wallace J L; Reuter B K; McKnight W; Bak A
Selective inhibitors of cyclooxygenase-2: are they really effective, selective, and GI-safe?
Journal of clinical gastroenterology 1998;27 Suppl 1():S28-34.
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1998: Bak A W; McKnight W; Li P; Del Soldato P; Calignano A; Cirino G; Wallace J L
Cyclooxygenase-independent chemoprevention with an aspirin derivative in a rat model of colonic adenocarcinoma.
Life sciences 1998;62(23):PL 367-73.
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1998: Muscará M N; McKnight W; Del Soldato P; Wallace J L
Effect of a nitric oxide-releasing naproxen derivative on hypertension and gastric damage induced by chronic nitric oxide inhibition in the rat.
Life sciences 1998;62(15):PL235-40.
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1998: Elliott S N; McKnight W; Davies N M; MacNaughton W K; Wallace J L
Alendronate induces gastric injury and delays ulcer healing in rodents.
Life sciences 1998;62(1):77-91.
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1997: Davies N M; Sharkey K A; Asfaha S; Macnaughton W K; Wallace J L
Aspirin causes rapid up-regulation of cyclo-oxygenase-2 expression in the stomach of rats.
Alimentary pharmacology & therapeutics 1997;11(6):1101-8.
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1997: Wallace J L; McKnight W; Wilson T L; Del Soldato P; Cirino G
Reduction of shock-induced gastric damage by a nitric oxide-releasing aspirin derivative: role of neutrophils.
The American journal of physiology 1997;273(6 Pt 1):G1246-51.
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1997: Ferraz J G; Sharkey K A; Reuter B K; Asfaha S; Tigley A W; Brown M L; McKnight W; Wallace J L
Induction of cyclooxygenase 1 and 2 in the rat stomach during endotoxemia: role in resistance to damage.
Gastroenterology 1997;113(1):195-204.
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1997: Ferraz J G; Tigley A W; Appleyard C B; Wallace J L
TNF-alpha contributes to the pathogenesis of ethanol-induced gastric damage in cirrhotic rats.
The American journal of physiology 1997;272(4 Pt 1):G809-14.
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1997: Wallace J L
Nonsteroidal anti-inflammatory drugs and gastroenteropathy: the second hundred years.
Gastroenterology 1997;112(3):1000-16.
-
1997: McCafferty D M; Wallace J L; Sharkey K A
Effects of chemical sympathectomy and sensory nerve ablation on experimental colitis in the rat.
The American journal of physiology 1997;272(2 Pt 1):G272-80.
-
1997: Swain M G; Appleyard C B; Wallace J L; Maric M
TNF-alpha facilitates inflammation-induced glucocorticoid secretion in rats with biliary obstruction.
Journal of hepatology 1997;26(2):361-8.
-
1997: Davies N M; Wallace J L
Nonsteroidal anti-inflammatory drug-induced gastrointestinal toxicity: new insights into an old problem.
Journal of gastroenterology 1997;32(1):127-33.
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1997: Davies N M; Røseth A G; Appleyard C B; McKnight W; Del Soldato P; Calignano A; Cirino G; Wallace J L
NO-naproxen vs. naproxen: ulcerogenic, analgesic and anti-inflammatory effects.
Alimentary pharmacology & therapeutics 1997;11(1):69-79.
-
1997: Reuter B K; Davies N M; Wallace J L
Nonsteroidal anti-inflammatory drug enteropathy in rats: role of permeability, bacteria, and enterohepatic circulation.
Gastroenterology 1997;112(1):109-17.
-
1997: Beck P L; Wallace J L
Cytokines in inflammatory bowel disease.
Mediators of inflammation 1997;6(2):95-103.
-
1996: Davies N M; Wallace J L
Selective inhibitors of cyclooxygenase-2. Potential in elderly patients.
Drugs & aging 1996;9(6):406-17.
-
1996: Rioux K P; Wallace J L
Long-term antigen challenge results in progressively diminished mucosal mast cell degranulation in rats.
Gastroenterology 1996;111(6):1516-23.
-
1996: Wallace J L
NSAID gastroenteropathy: past, present and future.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 1996;10(7):451-9.
-
1996: Reuter B K; Asfaha S; Buret A; Sharkey K A; Wallace J L
Exacerbation of inflammation-associated colonic injury in rat through inhibition of cyclooxygenase-2.
The Journal of clinical investigation 1996;98(9):2076-85.
-
1996: Wallace J L; Granger D N
The cellular and molecular basis of gastric mucosal defense.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1996;10(7):731-40.
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1996: Cirino G; Wheeler-Jones C P; Wallace J L; Del Soldato P; Baydoun A R
Inhibition of inducible nitric oxide synthase expression by novel nonsteroidal anti-inflammatory derivatives with gastrointestinal-sparing properties.
British journal of pharmacology 1996;117(7):1421-6.
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1996: Rioux K P; Wallace J L
Mast cells do not contribute to nonsteroidal anti-inflammatory drug-induced gastric mucosal injury in rodents.
Alimentary pharmacology & therapeutics 1996;10(2):173-80.
-
1996: Rioux K P; Sharkey K A; Wallace J L; Swain M G
Hepatic mucosal mast cell hyperplasia in rats with secondary biliary cirrhosis.
Hepatology (Baltimore, Md.) 1996;23(4):888-95.
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1996: Appleyard C B; McCafferty D M; Tigley A W; Swain M G; Wallace J L
Tumor necrosis factor mediation of NSAID-induced gastric damage: role of leukocyte adherence.
The American journal of physiology 1996;270(1 Pt 1):G42-8.
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1996: Geraldo J; Ferraz P; Wallace J L
Prostaglandins modulate the responsiveness of the gastric microcirculation of sodium nitroprusside in cirrhotic rats.
Hepatology (Baltimore, Md.) 1996;23(1):123-9.
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1995: Wallace J L; McKnight W; Del Soldato P; Baydoun A R; Cirino G
Anti-thrombotic effects of a nitric oxide-releasing, gastric-sparing aspirin derivative.
The Journal of clinical investigation 1995;96(6):2711-8.
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1995: McCafferty D M; Granger D N; Wallace J L
Indomethacin-induced gastric injury and leukocyte adherence in arthritic versus healthy rats.
Gastroenterology 1995;109(4):1173-80.
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1995: Wallace J L; Le T; Carter L; Appleyard C B; Beck P L
Hapten-induced chronic colitis in the rat: alternatives to trinitrobenzene sulfonic acid.
Journal of pharmacological and toxicological methods 1995;33(4):237-9.
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1995: Elliott S N; McKnight W; Cirino G; Wallace J L
A nitric oxide-releasing nonsteroidal anti-inflammatory drug accelerates gastric ulcer healing in rats.
Gastroenterology 1995;109(2):524-30.
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1995: Appleyard C B; Wallace J L
Reactivation of hapten-induced colitis and its prevention by anti-inflammatory drugs.
The American journal of physiology 1995;269(1 Pt 1):G119-25.
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1995: Cirino G; Cicala C; Mancuso F; Baydoun A R; Wallace J L
Flurbinitroxybutylester: a novel anti-inflammatory drug has enhanced antithrombotic activity.
Thrombosis research 1995;79(1):73-81.
-
1995: Wallace J L; Tigley A W
Review article: new insights into prostaglandins and mucosal defence.
Alimentary pharmacology & therapeutics 1995;9(3):227-35.
-
1995: Wallace J L; Cirino G; McKnight G W; Elliott S N
Reduction of gastrointestinal injury in acute endotoxic shock by flurbiprofen nitroxybutylester.
European journal of pharmacology 1995;280(1):63-8.
-
1995: Bell C J; Gall D G; Wallace J L
Disruption of colonic electrolyte transport in experimental colitis.
The American journal of physiology 1995;268(4 Pt 1):G622-30.
-
1995: Ferraz J G; McKnight W; Sharkey K A; Wallace J L
Impaired vasodilatory responses in the gastric microcirculation of anesthetized rats with secondary biliary cirrhosis.
Gastroenterology 1995;108(4):1183-91.
-
1995: Wallace J L; McKnight G W; Bell C J
Adaptation of rat gastric mucosa to aspirin requires mucosal contact.
The American journal of physiology 1995;268(1 Pt 1):G134-8.
-
1995: Carter L; Wallace J L
Alterations in rat peripheral blood neutrophil function as a consequence of colitis.
Digestive diseases and sciences 1995;40(1):192-7.
-
1995: Curtis G H; MacNaughton W K; Gall D G; Wallace J L
Intraluminal pH modulates gastric prostaglandin synthesis.
Canadian journal of physiology and pharmacology 1995;73(1):130-4.
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1995: Wallace J L; Pittman Q J; Cirino G
Nitric oxide-releasing NSAIDs: a novel class of GI-sparing anti-inflammatory drugs.
Agents and actions. Supplements 1995;46():121-9.
-
1994: Wallace J L
The 1994 Merck Frosst Award. Mechanisms of nonsteroidal anti-inflammatory drug (NSAID) induced gastrointestinal damage--potential for development of gastrointestinal tract safe NSAIDs.
Canadian journal of physiology and pharmacology 1994;72(12):1493-8.
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1994: Wallace J L; Carter L; McKnight W; Tries S; Laufer S
ML 3000 reduces gastric prostaglandin synthesis without causing mucosal injury.
European journal of pharmacology 1994;271(2-3):525-31.
-
1994: Wallace J L; Cirino G
The development of gastrointestinal-sparing nonsteroidal anti-inflammatory drugs.
Trends in pharmacological sciences 1994;15(11):405-6.
-
1994: Wallace J L; Reuter B; Cicala C; McKnight W; Grisham M B; Cirino G
Novel nonsteroidal anti-inflammatory drug derivatives with markedly reduced ulcerogenic properties in the rat.
Gastroenterology 1994;107(1):173-9.
-
1994: Ferraz J G; Tigley A; Wallace J L
Paradoxical effects of L-arginine on gastric mucosal integrity.
European journal of pharmacology 1994;260(1):107-11.
-
1994: Rioux K P; Wallace J L
Mast cell activation augments gastric mucosal injury through a leukotriene-dependent mechanism.
The American journal of physiology 1994;266(5 Pt 1):G863-9.
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1994: Wallace J L; Reuter B; Cicala C; McKnight W; Grisham M; Cirino G
A diclofenac derivative without ulcerogenic properties.
European journal of pharmacology 1994;257(3):249-55.
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1994: McCafferty D M; Sharkey K A; Wallace J L
Beneficial effects of local or systemic lidocaine in experimental colitis.
The American journal of physiology 1994;266(4 Pt 1):G560-7.
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1994: Dias V C; Shaffer E A; Wallace J L; Parsons H G
Bile salts determine leukotriene B4 synthesis in a human intestinal cell line (CaCo-2).
Digestive diseases and sciences 1994;39(4):802-8.
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1994: Sutherland L R; Verhoef M; Wallace J L; Van Rosendaal G; Crutcher R; Meddings J B
A simple, non-invasive marker of gastric damage: sucrose permeability.
Lancet 1994;343(8904):998-1000.
-
1994: Kanwar S; Wallace J L; Befus D; Kubes P
Nitric oxide synthesis inhibition increases epithelial permeability via mast cells.
The American journal of physiology 1994;266(2 Pt 1):G222-9.
-
1994: Hierlihy L E; Wallace J L; Ferguson A V
Autonomic pathways in development of neural stimulation-induced gastric mucosal damage.
The American journal of physiology 1994;266(2 Pt 1):G179-85.
-
1994: Reuter B K; Cirino G; Wallace J L
Markedly reduced intestinal toxicity of a diclofenac derivative.
Life sciences 1994;55(1):PL1-8.
-
1994: Wallace J L; Reuter B K; Cirino G
Nitric oxide-releasing non-steroidal anti-inflammatory drugs: a novel approach for reducing gastrointestinal toxicity.
Journal of gastroenterology and hepatology 1994;9 Suppl 1():S40-4.
-
1993: Wallace J L; McCafferty D M; Carter L; McKnight W; Argentieri D
Tissue-selective inhibition of prostaglandin synthesis in rat by tepoxalin: anti-inflammatory without gastropathy?
Gastroenterology 1993;105(6):1630-6.
-
1993: Beck P L; McKnight G W; Kelly J K; Wallace J L; Lee S S
Hepatic and gastric cytoprotective effects of long-term prostaglandin E1 administration in cirrhotic rats.
Gastroenterology 1993;105(5):1483-9.
-
1993: Wallace J L; McKnight W; Miyasaka M; Tamatani T; Paulson J; Anderson D C; Granger D N; Kubes P
Role of endothelial adhesion molecules in NSAID-induced gastric mucosal injury.
The American journal of physiology 1993;265(5 Pt 1):G993-8.
-
1993: Hogaboam C M; Befus A D; Wallace J L
Modulation of rat mast cell reactivity by IL-1 beta. Divergent effects on nitric oxide and platelet-activating factor release.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(7):3767-74.
-
1993: Hierlihy L E; Wallace J L; Ferguson A V
Role of gastric acid secretion and blood flow in the development of vagal stimulation induced gastric mucosal damage.
Canadian journal of physiology and pharmacology 1993;71(10-11):829-34.
-
1993: Beck P L; McKnight W; Lee S S; Wallace J L
Prostaglandin modulation of the gastric vasculature and mucosal integrity in cirrhotic rats.
The American journal of physiology 1993;265(3 Pt 1):G453-8.
-
1993: Higa A; McKnight G W; Wallace J L
Attenuation of epithelial injury in acute experimental colitis by immunomodulators.
European journal of pharmacology 1993;239(1-3):171-6.
-
1993: Bell C J; Wallace J L
Corticosteroid drugs and inflammation: the endothelial-leukocyte interface as a target for therapeutics.
Journal of pediatric gastroenterology and nutrition 1993;17(1):113-4.
-
1993: Wallace J L; McKnight G W
Characterization of a simple animal model for nonsteroidal anti-inflammatory drug induced antral ulcer.
Canadian journal of physiology and pharmacology 1993;71(7):447-52.
-
1993: Meddings J B; Sutherland L R; Byles N I; Wallace J L
Sucrose: a novel permeability marker for gastroduodenal disease.
Gastroenterology 1993;104(6):1619-26.
-
1993: Wallace J L; McKnight G W; Donigi-Gale D; Shoupe T S; Granger D N
Protective effects of PF-10040 in experimental NSAID-gastritis: role of leukocytes, leukotrienes and PAF.
Journal of lipid mediators 1993;7(2):183-96.
-
1993: McCafferty D M; Kubes P; Wallace J L
Inhibition of platelet-activating factor-induced leukocyte adhesion in vivo by a leumedin.
European journal of pharmacology 1993;232(2-3):169-72.
-
1993: Freedman S M; Wallace J L; Shaffer E A
Characterization of leukotriene-induced contraction of the guinea-pig gallbladder in vitro.
Canadian journal of physiology and pharmacology 1993;71(2):145-50.
-
1993: Wallace J L
Gastric ulceration: critical events at the neutrophil--endothelium interface.
Canadian journal of physiology and pharmacology 1993;71(1):98-102.
-
1993: Hogaboam C M; Bissonnette E Y; Chin B C; Befus A D; Wallace J L
Prostaglandins inhibit inflammatory mediator release from rat mast cells.
Gastroenterology 1993;104(1):122-9.
-
1992: Wallace J L; Rioux K P; McKnight W; Carter L; Jourd'heuil D; Meddings J; Zimmerman B J; Granger D N; Grisham M B
Hemoprotein-dependent production of a neutrophil-activating factor from arachidonic acid.
The American journal of physiology 1992;263(5 Pt 2):H1546-53.
-
1992: Wallace J L
Prostaglandins, NSAIDs, and cytoprotection.
Gastroenterology clinics of North America 1992;21(3):631-41.
-
1992: Beck P L; Lee S S; McKnight G W; Wallace J L
Characterization of spontaneous and ethanol-induced gastric damage in cirrhotic rats.
Gastroenterology 1992;103(3):1048-55.
-
1992: Parente L; Perretti M; Wallace J L; Mugridge K G
Mechanism of the protective action of interleukin-1 in the experimental gastric damage in the rat.
Pharmacological research : the official journal of the Italian Pharmacological Society 1992;26 Suppl 2():28-9.
-
1992: Wallace J L; McKnight G W; Befus A D
Capsaicin-induced hyperemia in the stomach: possible contribution of mast cells.
The American journal of physiology 1992;263(2 Pt 1):G209-14.
-
1992: Hierlihy L E; Wallace J L; Ferguson A V
Neurally mediated gastric mucosal damage in hypophysectomized rats.
Canadian journal of physiology and pharmacology 1992;70(8):1109-16.
-
1992: Wallace J L; Higa A; McKnight G W; MacIntyre D E
Prevention and reversal of experimental colitis by a monoclonal antibody which inhibits leukocyte adherence.
Inflammation 1992;16(4):343-54.
-
1992: Perretti M; Mugridge K G; Wallace J L; Parente L
Reduction of aspirin-induced gastric damage in rats by interleukin-1 beta: possible involvement of endogenous corticosteroids.
The Journal of pharmacology and experimental therapeutics 1992;261(3):1238-47.
-
1992: Hogaboam C M; Donigi-Gale D; Shoupe T S; Wallace J L
PF-5901 inhibits gastrointestinal platelet-activating factor synthesis in vivo.
European journal of pharmacology 1992;216(2):315-8.
-
1992: Vaananen P M; Keenan C M; Grisham M B; Wallace J L
Pharmacological investigation of the role of leukotrienes in the pathogenesis of experimental NSAID gastropathy.
Inflammation 1992;16(3):227-40.
-
1992: Dias V C; Wallace J L; Parsons H G
Modulation of cellular phospholipid fatty acids and leukotriene B4 synthesis in the human intestinal cell (CaCo-2).
Gut 1992;33(5):622-7.
-
1992: Wallace J L; Granger D N
Pathogenesis of NSAID gastropathy: are neutrophils the culprits?
Trends in pharmacological sciences 1992;13(4):129-31.
-
1992: Wallace J L; Keenan C M; Cucala M; Mugridge K G; Parente L
Mechanisms underlying the protective effects of interleukin 1 in experimental nonsteroidal anti-inflammatory drug gastropathy.
Gastroenterology 1992;102(4 Pt 1):1176-85.
-
1992: Hogaboam C M; Donigi-Gale D; Shoupe T S; Bissonnette E Y; Befus A D; Wallace J L
Platelet-activating factor synthesis by peritoneal mast cells and its inhibition by two quinoline-based compounds.
British journal of pharmacology 1992;105(1):87-92.
-
1992: Wallace J L; Keenan C M; Gale D; Shoupe T S
Exacerbation of experimental colitis by nonsteroidal anti-inflammatory drugs is not related to elevated leukotriene B4 synthesis.
Gastroenterology 1992;102(1):18-27.
-
1992: Freedman S M; Basu D K; Wallace J L; Shaffer E A
Leukotriene-induced contraction of isolated guinea pig gallbladder (GB) strips.
Advances in experimental medicine and biology 1992;311():437-8.
-
1992: Wallace J L; Hogaboam C M; Kubes P
Immunopathology of NSAID-gastropathy: inhibitory effects of interleukin-I and cyclosporin A.
Annals of the New York Academy of Sciences 1992;664():400-7.
-
1992: Wallace J L
Non-steroidal anti-inflammatory drug gastropathy and cytoprotection: pathogenesis and mechanisms re-examined.
Scandinavian journal of gastroenterology. Supplement 1992;192():3-8.
-
1992: McCafferty D M; Rioux K J; Wallace J L
Granulocyte infiltration in experimental colitis in the rat is interleukin-1 dependent and leukotriene independent.
Eicosanoids 1992;5(3-4):121-5.
-
1991: Bissonnette E Y; Hogaboam C M; Wallace J L; Befus A D
Potentiation of tumor necrosis factor-alpha-mediated cytotoxicity of mast cells by their production of nitric oxide.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(9):3060-5.
-
1991: Meddings J B; Hogaboam C M; Tran K; Reynolds J D; Wallace J L
Capsaicin effects on non-neuronal plasma membranes.
Biochimica et biophysica acta 1991;1070(1):43-50.
-
1991: Wallace J L; Cucala M; Mugridge K; Parente L
Secretagogue-specific effects of interleukin-1 on gastric acid secretion.
The American journal of physiology 1991;261(4 Pt 1):G559-64.
-
1991: Vaananen P M; Meddings J B; Wallace J L
Role of oxygen-derived free radicals in indomethacin-induced gastric injury.
The American journal of physiology 1991;261(3 Pt 1):G470-5.
-
1991: Wallace J L; Cirino G; Cicala C; Anderson D W; Argentieri D; Capetola R J
Comparison of the ulcerogenic properties of tepoxalin with those of non-steroidal anti-inflammatory drugs (NSAIDs).
Agents and actions 1991;34(1-2):247-50.
-
1991: Hogaboam C M; Wallace J L
Inhibition of platelet aggregation by capsaicin. An effect unrelated to actions on sensory afferent neurons.
European journal of pharmacology 1991;202(1):129-31.
-
1991: Hogaboam C M; Befus A D; Wallace J L
Intestinal platelet-activating factor synthesis during Nippostrongylus brasiliensis infection in the rat.
Journal of lipid mediators 1991;4(2):211-24.
-
1991: Hierlihy L E; Wallace J L; Ferguson A V
Vagal stimulation-induced gastric damage in rats.
The American journal of physiology 1991;261(1 Pt 1):G104-10.
-
1991: Wallace J L; Arfors K E; McKnight G W
A monoclonal antibody against the CD18 leukocyte adhesion molecule prevents indomethacin-induced gastric damage in the rabbit.
Gastroenterology 1991;100(4):878-83.
-
1991: Wallace J L
Possible mechanisms and mediators of gastritis associated with Helicobacter pylori infection.
Scandinavian journal of gastroenterology. Supplement 1991;187():65-70.
-
1990: Wallace J L; Keenan C M; Mugridge K G; Parente L
Reduction of the severity of experimental gastric and duodenal ulceration by interleukin-1 beta.
European journal of pharmacology 1990;186(2-3):279-84.
-
1990: Mathison R; Rimmer C; Davison J S; Wallace J L; Befus A D
Alterations in regional blood flow in rats following sensitization to the nematode Nippostrongylus brasiliensis: effects of PAF antagonists.
British journal of pharmacology 1990;101(1):93-6.
-
1990: Wallace J L; Keenan C M; Granger D N
Gastric ulceration induced by nonsteroidal anti-inflammatory drugs is a neutrophil-dependent process.
The American journal of physiology 1990;259(3 Pt 1):G462-7.
-
1990: Wallace J L; McKnight G W
The mucoid cap over superficial gastric damage in the rat. A high-pH microenvironment dissipated by nonsteroidal antiinflammatory drugs and endothelin.
Gastroenterology 1990;99(2):295-304.
-
1990: Wallace J L; Hogaboam C M; McKnight G W
Platelet-activating factor mediates gastric damage induced by hemorrhagic shock.
The American journal of physiology 1990;259(1 Pt 1):G140-6.
-
1990: Wallace J L; McKnight G W
Comparison of the damage-promoting effects of leukotrienes derived from eicosapentaenoic acid and arachidonic acid on the rat stomach.
The Journal of experimental medicine 1990;171(5):1827-32.
-
1990: Wallace J L; Keenan C M
Leukotriene B4 potentiates colonic ulceration in the rat.
Digestive diseases and sciences 1990;35(5):622-9.
-
1990: Wallace J L; McKnight G W; Keenan C M; Byles N I; MacNaughton W K
Effects of leukotrienes on susceptibility of the rat stomach to damage and investigation of the mechanism of action.
Gastroenterology 1990;98(5 Pt 1):1178-86.
-
1990: Wallace J L; Keenan C M
An orally active inhibitor of leukotriene synthesis accelerates healing in a rat model of colitis.
The American journal of physiology 1990;258(4 Pt 1):G527-34.
-
1990: Wallace J L
Mucosal defense. New avenues for treatment of ulcer disease?
Gastroenterology clinics of North America 1990;19(1):87-100.
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1990: Wallace J L
5-Lipoxygenase: a rational target for therapy of inflammatory bowel disease?
Trends in pharmacological sciences 1990;11(2):51-3.
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1990: Wallace J L
Lipid mediators of inflammation in gastric ulcer.
The American journal of physiology 1990;258(1 Pt 1):G1-11.
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1989: Guarner F; Wallace J L; MacNaughton W K; Ibbotson G C; Arroyo V; Rodés J
Endotoxin-induced ascites formation in the rat: partial mediation by platelet-activating factor.
Hepatology (Baltimore, Md.) 1989;10(5):788-94.
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1989: Ibbotson G C; Wallace J L
Inhibitory effects of dexamethasone in endotoxic shock and its relation to PAF-acether synthesis in the gastrointestinal tract and lung.
Journal of lipid mediators 1989;1(5):273-82.
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1989: Wallace J L; Keenan C M; MacNaughton W K; McKnight G W
Comparison of the effects of endothelin-1 and endothelin-3 on the rat stomach.
European journal of pharmacology 1989;167(1):41-7.
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1989: Morris G P; Keenan C M; MacNaughton W K; Wallace J L; Williamson T E
Protection of rat gastric mucosa by sucralfate. Effects of luminal stasis and of inhibition of prostaglandins synthesis.
The American journal of medicine 1989;86(6A):10-6.
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1989: Wallace J L; Cirino G; De Nucci G; McKnight W; MacNaughton W K
Endothelin has potent ulcerogenic and vasoconstrictor actions in the stomach.
The American journal of physiology 1989;256(4 Pt 1):G661-6.
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1989: MacNaughton W K; Wallace J L
A role for dopamine as an endogenous protective factor in the rat stomach.
Gastroenterology 1989;96(4):972-80.
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1989: Beck P L; Morris G P; Wallace J L
Reduction of ethanol-induced gastric damage by sodium cromoglycate and FPL-52694. Role of leukotrienes, prostaglandins, and mast cells in the protective mechanism.
Canadian journal of physiology and pharmacology 1989;67(4):287-93.
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1989: Morris G P; Beck P L; Herridge M S; Depew W T; Szewczuk M R; Wallace J L
Hapten-induced model of chronic inflammation and ulceration in the rat colon.
Gastroenterology 1989;96(3):795-803.
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1989: Ibbotson G C; Wallace J L
Beneficial effects of prostaglandin E2 in endotoxic shock are unrelated to effects on PAF-acether synthesis.
Prostaglandins 1989;37(2):237-50.
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1989: Wallace J L; MacNaughton W K; Morris G P; Beck P L
Inhibition of leukotriene synthesis markedly accelerates healing in a rat model of inflammatory bowel disease.
Gastroenterology 1989;96(1):29-36.
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1989: Wallace J L; Braquet P; Ibbotson G C; MacNaughton W K; Cirino G
Assessment of the role of platelet-activating factor in an animal model of inflammatory bowel disease.
Journal of lipid mediators 1989;1(1):13-23.
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1989: Wallace J L
Gastric resistance to acid: is the "mucus-bicarbonate barrier" functionally redundant?
The American journal of physiology 1989;256(1 Pt 1):G31-8.
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1989: Wallace J L
Extracellular mucus and repair of superficial mucosal injury by restitution.
Methods and findings in experimental and clinical pharmacology 1989;11 Suppl 1():27-33.
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1989: MacNaughton W K; Cirino G; Wallace J L
Endothelium-derived relaxing factor (nitric oxide) has protective actions in the stomach.
Life sciences 1989;45(20):1869-76.
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1989: MacNaughton W K; Keenan C M; McKnight G W; Wallace J L
The modulation of gastric mucosal integrity by endothelin-1 and prostacyclin.
Journal of cardiovascular pharmacology 1989;13 Suppl 5():S118-22; discussion S123.
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1988: Ferguson A V; Marcus P; Spencer J; Wallace J L
Paraventricular nucleus stimulation causes gastroduodenal mucosal necrosis in the rat.
The American journal of physiology 1988;255(5 Pt 2):R861-5.
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1988: Wallace J L; MacNaughton W K
Gastrointestinal damage induced by platelet-activating factor: role of leukotrienes.
European journal of pharmacology 1988;151(1):43-50.
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1988: Wallace J L; Morris G P; Beck P L; Williamson T E; Gingras G R
Effects of sucralfate on gastric prostaglandin and leukotriene synthesis: relationship to protective actions.
Canadian journal of physiology and pharmacology 1988;66(5):666-70.
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1988: Wallace J L
Release of platelet-activating factor (PAF) and accelerated healing induced by a PAF antagonist in an animal model of chronic colitis.
Canadian journal of physiology and pharmacology 1988;66(4):422-5.
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1988: Wallace J L; Beck P L; Morris G P
Is there a role for leukotrienes as mediators of ethanol-induced gastric mucosal damage?
The American journal of physiology 1988;254(1 Pt 1):G117-23.
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1988: Wallace J L
Increased resistance of the rat gastric mucosa to hemorrhagic damage after exposure to an irritant. Role of the "mucoid cap" and prostaglandin synthesis.
Gastroenterology 1988;94(1):22-32.
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1987: Wallace J L
Glucocorticoid-induced gastric mucosal damage: inhibition of leukotriene, but not prostaglandin biosynthesis.
Prostaglandins 1987;34(2):311-23.
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1987: Wallace J L; Steel G; Whittle B J
Gastrointestinal plasma leakage in endotoxic shock. Inhibition by prostaglandin E2 and by a platelet-activating factor antagonist.
Canadian journal of physiology and pharmacology 1987;65(7):1428-32.
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