John Wallace

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Living Beings

Anatomy

Chemicals & Drugs

Disorders

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Wallace John L; Vong Linda; McKnight Webb; Dicay Michael; Martin Gary R
Endogenous and exogenous hydrogen sulfide promotes resolution of colitis in rats.
McKay Derek M; Wallace John L
Acetic acid induced ulceration in rats is not affected by infection with Hymenolepis diminuta.
Wallace John L; Vong Linda
NSAID-induced gastrointestinal damage and the design of GI-sparing NSAIDs.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of John Wallace (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Wallace John L; Vong Linda; McKnight Webb; Dicay Michael; Martin Gary R
Endogenous and exogenous hydrogen sulfide promotes resolution of colitis in rats.
Gastroenterology 2009;137(2):569-78, 578.e1.
2009: McKay Derek M; Wallace John L
Acetic acid induced ulceration in rats is not affected by infection with Hymenolepis diminuta.
The Journal of parasitology 2009;95(2):481-2.
2008: Wallace John L; Vong Linda
NSAID-induced gastrointestinal damage and the design of GI-sparing NSAIDs.
Current opinion in investigational drugs (London, England : 2000) 2008;9(11):1151-6.
2008: Chávez-Piña A E; Vong L; McKnight W; Dicay M; Zanardo R C O; Ortiz M I; Castañeda-Hernández G; Wallace J L
Lack of effects of acemetacin on signalling pathways for leukocyte adherence may explain its gastrointestinal safety.
British journal of pharmacology 2008;155(6):857-64.
2008: Martin Gary R; Perretti Mauro; Flower Roderick J; Wallace John L
Annexin-1 modulates repair of gastric mucosal injury.
American journal of physiology. Gastrointestinal and liver physiology 2008;294(3):G764-9.
2007: Wallace John L; Dicay Michael; McKnight Webb; Martin Gary R
Hydrogen sulfide enhances ulcer healing in rats.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(14):4070-6.
2007: Chávez-Piña A E; McKnight W; Dicay M; Castañeda-Hernández G; Wallace J L
Mechanisms underlying the anti-inflammatory activity and gastric safety of acemetacin.
British journal of pharmacology 2007;152(6):930-8.
2007: Wallace John L
Hydrogen sulfide-releasing anti-inflammatory drugs.
Trends in pharmacological sciences 2007;28(10):501-5.
2007: Wallace J L
Building a better aspirin: gaseous solutions to a century-old problem.
British journal of pharmacology 2007;152(4):421-8.
2007: Fiorucci S; Orlandi S; Mencarelli A; Caliendo G; Santagada V; Distrutti E; Santucci L; Cirino G; Wallace J L
Enhanced activity of a hydrogen sulphide-releasing derivative of mesalamine (ATB-429) in a mouse model of colitis.
British journal of pharmacology 2007;150(8):996-1002.
2007: Moreira Vanessa; Zamuner Stella Regina; Wallace John L; Teixeira Catarina de Fátima Pereira
Bothrops jararaca and Crotalus durissus terrificus venoms elicit distinct responses regarding to production of prostaglandins E2 and D2, and expression of cyclooxygenases.
Toxicon : official journal of the International Society on Toxinology 2007;49(5):615-24.
2007: Olivo Renata do A; Teixeira Catarina F P; Wallace John L; Gutierrez Jose M; Zamuner Stella R
Role of cyclooxygenases in oedema-forming activity of bothropic venoms.
Toxicon : official journal of the International Society on Toxinology 2007;49(5):670-7.
2007: Wallace John L; Caliendo Giuseppe; Santagada Vincenzo; Cirino Giuseppe; Fiorucci Stefano
Gastrointestinal safety and anti-inflammatory effects of a hydrogen sulfide-releasing diclofenac derivative in the rat.
Gastroenterology 2007;132(1):261-71.
2006: Skinn Andrew C; Vergnolle Nathalie; Zamuner Stella R; Wallace John L; Cellars Laurie; MacNaughton Wallace K; Sherman Philip M
Citrobacter rodentium infection causes iNOS-independent intestinal epithelial dysfunction in mice.
Canadian journal of physiology and pharmacology 2006;84(12):1301-12.
2006: Zanardo Renata C O; Brancaleone Vincenzo; Distrutti Eleonora; Fiorucci Stefano; Cirino Giuseppe; Wallace John L
Hydrogen sulfide is an endogenous modulator of leukocyte-mediated inflammation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(12):2118-20.
2006: Distrutti Eleonora; Sediari Luca; Mencarelli Andrea; Renga Barbara; Orlandi Stefano; Russo Giuseppe; Caliendo Giuseppe; Santagada Vincenzo; Cirino Giuseppe; Wallace John L; Fiorucci Stefano
5-Amino-2-hydroxybenzoic acid 4-(5-thioxo-5H-[1,2]dithiol-3yl)-phenyl ester (ATB-429), a hydrogen sulfide-releasing derivative of mesalamine, exerts antinociceptive effects in a model of postinflammatory hypersensitivity.
The Journal of pharmacology and experimental therapeutics 2006;319(1):447-58.
2006: Vergnolle Nathalie; Cellars Laurie; Mencarelli Andrea; Rizzo Giovanni; Swaminathan Sunita; Beck Paul; Steinhoff Martin; Andrade-Gordon Patricia; Bunnett Nigel W; Hollenberg Morley D; Wallace John L; Cirino Giuseppe; Fiorucci Stefano
A role for proteinase-activated receptor-1 in inflammatory bowel diseases.
The Journal of clinical investigation 2006;116(7):2056.
2006: Fiorucci Stefano; Distrutti Eleonora; Cirino Giuseppe; Wallace John L
The emerging roles of hydrogen sulfide in the gastrointestinal tract and liver.
Gastroenterology 2006;131(1):259-71.
2006: Wallace John L; Dicay Michael; McKnight Webb; Dudar Genevieve K
Platelets accelerate gastric ulcer healing through presentation of vascular endothelial growth factor.
British journal of pharmacology 2006;148(3):274-8.
2006: Wallace John L
Nitric oxide, aspirin-triggered lipoxins and NO-aspirin in gastric protection.
Inflammation & allergy drug targets 2006;5(2):133-7.
2006: Muscará Marcelo N; Wallace John L
COX-inhibiting nitric oxide donors (CINODs): potential benefits on cardiovascular and renal function.
Cardiovascular & hematological agents in medicinal chemistry 2006;4(2):155-64.
2006: Wallace John L
Commonality of defensive roles of COX-2 in the lung and gut.
The American journal of pathology 2006;168(4):1060-3.
2006: Martin Gary R; Wallace John L
Gastrointestinal inflammation: a central component of mucosal defense and repair.
Experimental biology and medicine (Maywood, N.J.) 2006;231(2):130-7.
2006: Distrutti Eleonora; Sediari Luca; Mencarelli Andrea; Renga Barbara; Orlandi Stefano; Antonelli Elisabetta; Roviezzo Fiorenza; Morelli Antonio; Cirino Giuseppe; Wallace John L; Fiorucci Stefano
Evidence that hydrogen sulfide exerts antinociceptive effects in the gastrointestinal tract by activating KATP channels.
The Journal of pharmacology and experimental therapeutics 2006;316(1):325-35.
2006: Wallace John L
COX-2: a pivotal enzyme in mucosal protection and resolution of inflammation.
TheScientificWorldJournal 2006;6():577-88.
2005: Wallace John L
Recent advances in gastric ulcer therapeutics.
Current opinion in pharmacology 2005;5(6):573-7.
2005: Zamuner Stella R; Bak Adrian W; Devchand Pallavi R; Wallace John L
Predisposition to colorectal cancer in rats with resolved colitis: role of cyclooxygenase-2-derived prostaglandin d2.
The American journal of pathology 2005;167(5):1293-300.
2005: Fiorucci Stefano; Antonelli Elisabetta; Distrutti Eleonora; Rizzo Giovanni; Mencarelli Andrea; Orlandi Stefano; Zanardo Renata; Renga Barbara; Di Sante Moses; Morelli Antonio; Cirino Giuseppe; Wallace John L
Inhibition of hydrogen sulfide generation contributes to gastric injury caused by anti-inflammatory nonsteroidal drugs.
Gastroenterology 2005;129(4):1210-24.
2005: Perini Rafael; Wallace John L; Ma Li
Roles of platelets and proteinase-activated receptors in gastric ulcer healing.
Digestive diseases and sciences 2005;50 Suppl 1():S12-5.
2005: Santos Camila L; Souza Marcellus H L P; Gomes Antoniella S; Lemos Henrique P; Santos Armênio A; Cunha Fernando Q; Wallace John L
Sildenafil prevents indomethacin-induced gastropathy in rats: role of leukocyte adherence and gastric blood flow.
British journal of pharmacology 2005;146(4):481-6.
2005: Cenac Nicolas; Cellars Laurie; Steinhoff Martin; Andrade-Gordon Patricia; Hollenberg Morley Donald; Wallace John Lawrence; Fiorucci Stefano; Vergnolle Nathalie
Proteinase-activated receptor-1 is an anti-inflammatory signal for colitis mediated by a type 2 immune response.
Inflammatory bowel diseases 2005;11(9):792-8.
2005: Wallace John L; de Lima Octavio Menezes; Fiorucci Stefano
Lipoxins in gastric mucosal health and disease.
Prostaglandins, leukotrienes, and essential fatty acids 2005;73(3-4):251-5.
2005: Hansen Kristina K; Sherman Philip M; Cellars Laurie; Andrade-Gordon Patricia; Pan Zhengying; Baruch Amos; Wallace John L; Hollenberg Morley D; Vergnolle Nathalie
A major role for proteolytic activity and proteinase-activated receptor-2 in the pathogenesis of infectious colitis.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(23):8363-8.
2005: Wallace John L; Devchand Pallavi R
Emerging roles for cyclooxygenase-2 in gastrointestinal mucosal defense.
British journal of pharmacology 2005;145(3):275-82.
2005: Chou May M; Vergnolle Nathalie; McDougall Jason J; Wallace John L; Marty Stephanie; Teskey Val; Buret Andre G
Effects of chondroitin and glucosamine sulfate in a dietary bar formulation on inflammation, interleukin-1beta, matrix metalloprotease-9, and cartilage damage in arthritis.
Experimental biology and medicine (Maywood, N.J.) 2005;230(4):255-62.
2005: Wallace John L
Nitric oxide as a regulator of inflammatory processes.
Memórias do Instituto Oswaldo Cruz 2005;100 Suppl 1():5-9.
2005: Zanardo Renata C O; Perretti Mauro; Wallace John L
Annexin-1 is an endogenous gastroprotective factor against indomethacin-induced damage.
American journal of physiology. Gastrointestinal and liver physiology 2005;288(3):G481-6.
2005: Ma Li; Perini Rafael; McKnight Webb; Dicay Michael; Klein Andre; Hollenberg Morley D; Wallace John L
Proteinase-activated receptors 1 and 4 counter-regulate endostatin and VEGF release from human platelets.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(1):216-20.
2004: Vergnolle Nathalie; Cellars Laurie; Mencarelli Andrea; Rizzo Giovanni; Swaminathan Sunita; Beck Paul; Steinhoff Martin; Andrade-Gordon Patricia; Bunnett Nigel W; Hollenberg Morley D; Wallace John L; Cirino Giuseppe; Fiorucci Stefano
A role for proteinase-activated receptor-1 in inflammatory bowel diseases.
The Journal of clinical investigation 2004;114(10):1444-56.
2004: Fiorucci Stefano; Wallace John L; Mencarelli Andrea; Distrutti Eleonora; Rizzo Giovanni; Farneti Silvana; Morelli Antonio; Tseng Jih-Lie; Suramanyam Babu; Guilford William J; Parkinson John F
A beta-oxidation-resistant lipoxin A4 analog treats hapten-induced colitis by attenuating inflammation and immune dysfunction.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(44):15736-41.
2004: Hyun Eric; Bolla Manlio; Steinhoff Martin; Wallace John L; Soldato Piero Del; Vergnolle Nathalie
Anti-inflammatory effects of nitric oxide-releasing hydrocortisone NCX 1022, in a murine model of contact dermatitis.
British journal of pharmacology 2004;143(5):618-25.
2004: Antony Joseph M; van Marle Guido; Opii Wycliffe; Butterfield D Allan; Mallet François; Yong Voon Wee; Wallace John L; Deacon Robert M; Warren Kenneth; Power Christopher
Human endogenous retrovirus glycoprotein-mediated induction of redox reactants causes oligodendrocyte death and demyelination.
Nature neuroscience 2004;7(10):1088-95.
2004: Wallace John L
Acetaminophen hepatotoxicity: NO to the rescue.
British journal of pharmacology 2004;143(1):1-2.
2004: von der Weid Pierre-Yves; Hollenberg Morley D; Fiorucci Stefano; Wallace John L
Aspirin-triggered, cyclooxygenase-2-dependent lipoxin synthesis modulates vascular tone.
Circulation 2004;110(10):1320-5.
2004: Wallace John L; Rizzo Gianni; Cirino Giuseppe; Del Soldato Piero; Fiorucci Stefano
Enhanced anti-inflammatory potency of a nitric oxide-releasing derivative of flunisolide: role of nuclear factor-kappaB.
The Journal of pharmacology and experimental therapeutics 2004;310(3):1096-102.
2004: Alshurafa Hashem N; Stenton Grant R; Wallace John L; Hollenberg Morley D; Befus A Dean; Vliagoftis Harissios
A protease activated receptor-2 (PAR-2) activating peptide, tc-LIGRLO-NH2, induces protease release from mast cells: role in TNF degradation.
BMC pharmacology 2004;4():12.
2004: Fiorucci Stefano; Distrutti Eleonora; Mencarelli Andrea; Rizzo Giovanni; Lorenzo Anna Rita Di; Baldoni Monia; Del Soldato Piero; Morelli Antonio; Wallace John L
Cooperation between aspirin-triggered lipoxin and nitric oxide (NO) mediates antiadhesive properties of 2-(Acetyloxy)benzoic acid 3-(nitrooxymethyl)phenyl ester (NCX-4016) (NO-aspirin) on neutrophil-endothelial cell adherence.
The Journal of pharmacology and experimental therapeutics 2004;309(3):1174-82.
2004: Wallace John L; Muscará Marcelo N; de Nucci Gilberto; Zamuner Stella; Cirino Giuseppe; del Soldato Piero; Ongini Ennio
Gastric tolerability and prolonged prostaglandin inhibition in the brain with a nitric oxide-releasing flurbiprofen derivative, NCX-2216 [3-[4-(2-fluoro-alpha-methyl-[1,1'-biphenyl]-4-acetyloxy)-3-methoxyphenyl]-2-propenoic acid 4-nitrooxy butyl ester].
The Journal of pharmacology and experimental therapeutics 2004;309(2):626-33.
2004: Perini Rafael; Fiorucci Stefano; Wallace John L
Mechanisms of nonsteroidal anti-inflammatory drug-induced gastrointestinal injury and repair: a window of opportunity for cyclooxygenase-inhibiting nitric oxide donors.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 2004;18(4):229-36.
2004: Wallace John L; Zamuner Stella R; McKnight Webb; Dicay Michael; Mencarelli Andrea; del Soldato Piero; Fiorucci Stefano
Aspirin, but not NO-releasing aspirin (NCX-4016), interacts with selective COX-2 inhibitors to aggravate gastric damage and inflammation.
American journal of physiology. Gastrointestinal and liver physiology 2004;286(1):G76-81.
2003: Zamuner S R; Warrier N; Buret A G; MacNaughton W K; Wallace J L
Cyclooxygenase 2 mediates post-inflammatory colonic secretory and barrier dysfunction.
Gut 2003;52(12):1714-20.
2003: Nguyen Cathy; Coelho Anne-Marie; Grady Eileen; Compton Steven J; Wallace John L; Hollenberg Morley D; Cenac Nicolas; Garcia-Villar Rafael; Bueno Lionel; Steinhoff Martin; Bunnett Nigel W; Vergnolle Nathalie
Colitis induced by proteinase-activated receptor-2 agonists is mediated by a neurogenic mechanism.
Canadian journal of physiology and pharmacology 2003;81(9):920-7.
2003: Chin Alex C; Vergnolle Nathalie; MacNaughton Wallace K; Wallace John L; Hollenberg Morley D; Buret Andre G
Proteinase-activated receptor 1 activation induces epithelial apoptosis and increases intestinal permeability.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(19):11104-9.
2003: Fiorucci Stefano; Santucci Luca; Wallace John L; Sardina Marco; Romano Mario; del Soldato Piero; Morelli Antonio
Interaction of a selective cyclooxygenase-2 inhibitor with aspirin and NO-releasing aspirin in the human gastric mucosa.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(19):10937-41.
2003: Fiorucci Stefano; Distrutti Eleonora; Mencarelli Andrea; Morelli Antonio; Laufor Stefan A; Cirino Giuseppe; Wallace John L
Evidence that 5-lipoxygenase and acetylated cyclooxygenase 2-derived eicosanoids regulate leukocyte-endothelial adherence in response to aspirin.
British journal of pharmacology 2003;139(7):1351-9.
2003: Wallace John L; Fiorucci Stefano
A magic bullet for mucosal protection...and aspirin is the trigger!
Trends in pharmacological sciences 2003;24(7):323-6.
2003: Turesin Fusun; del Soldato Piero; Wallace John L
Enhanced anti-inflammatory potency of a nitric oxide-releasing prednisolone derivative in the rat.
British journal of pharmacology 2003;139(5):966-72.
2003: Souza Marcellus H L P; de Lima Octavio Menezes; Zamuner Stella R; Fiorucci Stefano; Wallace John L
Gastritis increases resistance to aspirin-induced mucosal injury via COX-2-mediated lipoxin synthesis.
American journal of physiology. Gastrointestinal and liver physiology 2003;285(1):G54-61.
2003: Fiorucci Stefano; Distrutti Eleonora; de Lima Octavio Menezes; Romano Mario; Mencarelli Andrea; Barbanti Miriam; Palazzini Ernesto; Morelli Antonio; Wallace John L
Relative contribution of acetylated cyclo-oxygenase (COX)-2 and 5-lipooxygenase (LOX) in regulating gastric mucosal integrity and adaptation to aspirin.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(9):1171-3.
2003: Wallace J L
Nitric oxide-releasing mesalamine: potential utility for treatment of inflammatory bowel disease.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2003;35 Suppl 2():S35-40.
2003: Thomson A B R; Appleman S; Keelan M; Wallace J L
Role of gastric mucosal and gastric juice cytokine concentrations in development of bisphosphonate damage to gastric mucosa.
Digestive diseases and sciences 2003;48(2):308-14.
2003: Wallace John L; Del Soldato Piero
The therapeutic potential of NO-NSAIDs.
Fundamental & clinical pharmacology 2003;17(1):11-20.
2003: Perini Rafael F; Ma Li; Wallace John L
Mucosal repair and COX-2 inhibition.
Current pharmaceutical design 2003;9(27):2207-11.
2002: Cenac Nicolas; Coelho Anne-Marie; Nguyen Cathy; Compton Steven; Andrade-Gordon Patricia; MacNaughton Wallace K; Wallace John L; Hollenberg Morley D; Bunnett Nigel W; Garcia-Villar Rafael; Bueno Lionel; Vergnolle Nathalie
Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2.
The American journal of pathology 2002;161(5):1903-15.
2002: Fiorucci Stefano; de Lima Octavio Menezes; Mencarelli Andrea; Palazzetti Barbara; Distrutti Eleonora; McKnight Webb; Dicay Michael; Ma Li; Romano Mario; Morelli Antonio; Wallace John L
Cyclooxygenase-2-derived lipoxin A4 increases gastric resistance to aspirin-induced damage.
Gastroenterology 2002;123(5):1598-606.
2002: Ma Li; del Soldato Piero; Wallace John L
Divergent effects of new cyclooxygenase inhibitors on gastric ulcer healing: Shifting the angiogenic balance.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(20):13243-7.
2002: Stenton Grant R; Nohara Osamu; Déry René E; Vliagoftis Harissios; Gilchrist Mark; Johri Ankur; Wallace John L; Hollenberg Morley D; Moqbel Redwan; Befus A Dean
Proteinase-activated receptor (PAR)-1 and -2 agonists induce mediator release from mast cells by pathways distinct from PAR-1 and PAR-2.
The Journal of pharmacology and experimental therapeutics 2002;302(2):466-74.
2002: Wallace John L; Ignarro Louis J; Fiorucci Stefano
Potential cardioprotective actions of no-releasing aspirin.
Nature reviews. Drug discovery 2002;1(5):375-82.
2002: Gilchrist Mark; Savoie Michelle; Nohara Osamu; Wills Fiona L; Wallace John L; Befus A D
Nitric oxide synthase and nitric oxide production in in vivo-derived mast cells.
Journal of leukocyte biology 2002;71(4):618-24.
2002: Rossoni Giuseppe; Muscara Marcelo N; Cirino Giuseppe; Wallace John L
Inhibition of cyclo-oxygenase-2 exacerbates ischaemia-induced acute myocardial dysfunction in the rabbit.
British journal of pharmacology 2002;135(6):1540-6.
2002: Fiorucci Stefano; Antonelli Elisabetta; Mencarelli Andrea; Palazzetti Barbara; Alvarez-Miller Lorena; Muscara Marcelo; del Soldato Piero; Sanpaolo Laura; Wallace John L; Morelli Antonio
A NO-releasing derivative of acetaminophen spares the liver by acting at several checkpoints in the Fas pathway.
British journal of pharmacology 2002;135(3):589-99.
2001: Wallace J L; Muscará M N
Selective cyclo-oxygenase-2 inhibitors: cardiovascular and gastrointestinal toxicity.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2001;33 Suppl 2():S21-8.
2001: Wallace J L; Ma L
Inflammatory mediators in gastrointestinal defense and injury.
Experimental biology and medicine (Maywood, N.J.) 2001;226(11):1003-15.
2001: Fiorucci S; Mencarelli A; Palazzetti B; Distrutti E; Vergnolle N; Hollenberg M D; Wallace J L; Morelli A; Cirino G
Proteinase-activated receptor 2 is an anti-inflammatory signal for colonic lamina propria lymphocytes in a mouse model of colitis.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(24):13936-41.
2001: Ma L; Hollenberg M D; Wallace J L
Thrombin-induced platelet endostatin release is blocked by a proteinase activated receptor-4 (PAR4) antagonist.
British journal of pharmacology 2001;134(4):701-4.
2001: Wallace J L
Pathogenesis of NSAID-induced gastroduodenal mucosal injury.
Best practice & research. Clinical gastroenterology 2001;15(5):691-703.
2001: Fiorucci S; Distrutti E; Ajuebor M N; Mencarelli A; Mannucci R; Palazzetti B; Del Soldato P; Morelli A; Wallace J L
NO-mesalamine protects colonic epithelial cells against apoptotic damage induced by proinflammatory cytokines.
American journal of physiology. Gastrointestinal and liver physiology 2001;281(3):G654-65.
2001: Asfaha S; MacNaughton W K; Appleyard C B; Chadee K; Wallace J L
Persistent epithelial dysfunction and bacterial translocation after resolution of intestinal inflammation.
American journal of physiology. Gastrointestinal and liver physiology 2001;281(3):G635-44.
2001: Muscará M N; Lovren F; McKnight W; Dicay M; del Soldato P; Triggle C R; Wallace J L
Vasorelaxant effects of a nitric oxide-releasing aspirin derivative in normotensive and hypertensive rats.
British journal of pharmacology 2001;133(8):1314-22.
2001: Buresi M C; Schleihauf E; Vergnolle N; Buret A; Wallace J L; Hollenberg M D; MacNaughton W K
Protease-activated receptor-1 stimulates Ca(2+)-dependent Cl(-) secretion in human intestinal epithelial cells.
American journal of physiology. Gastrointestinal and liver physiology 2001;281(2):G323-32.
2001: Vergnolle N; Bunnett N W; Sharkey K A; Brussee V; Compton S J; Grady E F; Cirino G; Gerard N; Basbaum A I; Andrade-Gordon P; Hollenberg M D; Wallace J L
Proteinase-activated receptor-2 and hyperalgesia: A novel pain pathway.
Nature medicine 2001;7(7):821-6.
2001: Ma L; Elliott S N; Cirino G; Buret A; Ignarro L J; Wallace J L
Platelets modulate gastric ulcer healing: role of endostatin and vascular endothelial growth factor release.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(11):6470-5.
2001: Vergnolle N; Wallace J L; Bunnett N W; Hollenberg M D
Protease-activated receptors in inflammation, neuronal signaling and pain.
Trends in pharmacological sciences 2001;22(3):146-52.
2001: Wallace J L
Nonsteroidal anti-inflammatory drugs and the gastrointestinal tract. Mechanisms of protection and healing: current knowledge and future research.
The American journal of medicine 2001;110(1A):19S-23S.
2001: Ajuebor M N; Hogaboam C M; Kunkel S L; Proudfoot A E; Wallace J L
The chemokine RANTES is a crucial mediator of the progression from acute to chronic colitis in the rat.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(1):552-8.
2000: Barnett K; Bell C J; McKnight W; Dicay M; Sharkey K A; Wallace J L
Role of cyclooxygenase-2 in modulating gastric acid secretion in the normal and inflamed rat stomach.
American journal of physiology. Gastrointestinal and liver physiology 2000;279(6):G1292-7.
2000: Vliagoftis H; Schwingshackl A; Milne C D; Duszyk M; Hollenberg M D; Wallace J L; Befus A D; Moqbel R
Proteinase-activated receptor-2-mediated matrix metalloproteinase-9 release from airway epithelial cells.
The Journal of allergy and clinical immunology 2000;106(3):537-45.
2000: Wallace J L; McKnight W; Reuter B K; Vergnolle N
NSAID-induced gastric damage in rats: requirement for inhibition of both cyclooxygenase 1 and 2.
Gastroenterology 2000;119(3):706-14.
2000: Wallace J L; Miller M J
Nitric oxide in mucosal defense: a little goes a long way.
Gastroenterology 2000;119(2):512-20.
2000: Muscará M N; McKnight W; Lovren F; Triggle C R; Cirino G; Wallace J L
Antihypertensive properties of a nitric oxide-releasing naproxen derivative in two-kidney, one-clip rats.
American journal of physiology. Heart and circulatory physiology 2000;279(2):H528-35.
2000: Ma L; Wallace J L
Endothelial nitric oxide synthase modulates gastric ulcer healing in rats.
American journal of physiology. Gastrointestinal and liver physiology 2000;279(2):G341-6.
2000: Cicala C; Ianaro A; Fiorucci S; Calignano A; Bucci M; Gerli R; Santucci L; Wallace J L; Cirino G
NO-naproxen modulates inflammation, nociception and downregulates T cell response in rat Freund's adjuvant arthritis.
British journal of pharmacology 2000;130(6):1399-405.
2000: Ajuebor M N; Singh A; Wallace J L
Cyclooxygenase-2-derived prostaglandin D(2) is an early anti-inflammatory signal in experimental colitis.
American journal of physiology. Gastrointestinal and liver physiology 2000;279(1):G238-44.
2000: McCafferty D M; Sihota E; Muscara M; Wallace J L; Sharkey K A; Kubes P
Spontaneously developing chronic colitis in IL-10/iNOS double-deficient mice.
American journal of physiology. Gastrointestinal and liver physiology 2000;279(1):G90-9.
2000: Muscará M N; Vergnolle N; Lovren F; Triggle C R; Elliott S N; Asfaha S; Wallace J L
Selective cyclo-oxygenase-2 inhibition with celecoxib elevates blood pressure and promotes leukocyte adherence.
British journal of pharmacology 2000;129(7):1423-30.
2000: Wallace J L
How do NSAIDs cause ulcer disease?
Baillière's best practice & research. Clinical gastroenterology 2000;14(1):147-59.
2000: Muscará M N; McKnight W; Asfaha S; Wallace J L
Wound collagen deposition in rats: effects of an NO-NSAID and a selective COX-2 inhibitor.
British journal of pharmacology 2000;129(4):681-6.
2000: Elliott S N; Wallace J L; McKnight W; Gall D G; Hardin J A; Olson M; Buret A
Bacterial colonization and healing of gastric ulcers: the effects of epidermal growth factor.
American journal of physiology. Gastrointestinal and liver physiology 2000;278(1):G105-12.
1999: Wallace J L
Distribution and expression of cyclooxygenase (COX) isoenzymes, their physiological roles, and the categorization of nonsteroidal anti-inflammatory drugs (NSAIDs).
The American journal of medicine 1999;107(6A):11S-16S; discussion 16S-17S.
1999: Wallace J L; Dicay M; McKnight W; Bastaki S; Blank M A
N-bisphosphonates cause gastric epithelial injury independent of effects on the microcirculation.
Alimentary pharmacology & therapeutics 1999;13(12):1675-82.
1999: Reuter B K; Wallace J L
Phosphodiesterase inhibitors prevent NSAID enteropathy independently of effects on TNF-alpha release.
The American journal of physiology 1999;277(4 Pt 1):G847-54.
1999: Wallace J L; Vergnolle N; Muscará M N; Asfaha S; Chapman K; McKnight W; Del Soldato P; Morelli A; Fiorucci S
Enhanced anti-inflammatory effects of a nitric oxide-releasing derivative of mesalamine in rats.
Gastroenterology 1999;117(3):557-66.
1999: Vergnolle N; Hollenberg M D; Sharkey K A; Wallace J L
Characterization of the inflammatory response to proteinase-activated receptor-2 (PAR2)-activating peptides in the rat paw.
British journal of pharmacology 1999;127(5):1083-90.
1999: Muscará M N; Wallace J L
Nitric Oxide. V. therapeutic potential of nitric oxide donors and inhibitors.
The American journal of physiology 1999;276(6 Pt 1):G1313-6.
1999: Vergnolle N; Hollenberg M D; Wallace J L
Pro- and anti-inflammatory actions of thrombin: a distinct role for proteinase-activated receptor-1 (PAR1).
British journal of pharmacology 1999;126(5):1262-8.
1999: Wallace J L; Chapman K; McKnight W
Limited anti-inflammatory efficacy of cyclo-oxygenase-2 inhibition in carrageenan-airpouch inflammation.
British journal of pharmacology 1999;126(5):1200-4.
1999: Bastaki S M; Wallace J L
Pathogenesis of nonsteroidal anti-inflammatory drug gastropathy: clues to preventative therapy.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 1999;13(2):123-7.
1999: Asfaha S; Bell C J; Wallace J L; MacNaughton W K
Prolonged colonic epithelial hyporesponsiveness after colitis: role of inducible nitric oxide synthase.
The American journal of physiology 1999;276(3 Pt 1):G703-10.
1999: Wallace J L
Selective COX-2 inhibitors: is the water becoming muddy?
Trends in pharmacological sciences 1999;20(1):4-6.
1999: Wallace J L; Muscara M N; McKnight W; Dicay M; Del Soldato P; Cirino G
In vivo antithrombotic effects of a nitric oxide-releasing aspirin derivative, NCX-4016.
Thrombosis research 1999;93(1):43-50.
1998: Elliott S N; Wallace J L
Nitric oxide: a regulator of mucosal defense and injury.
Journal of gastroenterology 1998;33(6):792-803.
1998: Elliott S N; Wallace J L
Neutrophil-mediated gastrointestinal injury.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 1998;12(8):559-68.
1998: Elliott S N; Buret A; McKnight W; Miller M J; Wallace J L
Bacteria rapidly colonize and modulate healing of gastric ulcers in rats.
The American journal of physiology 1998;275(3 Pt 1):G425-32.
1998: Wallace J L; Bak A; McKnight W; Asfaha S; Sharkey K A; MacNaughton W K
Cyclooxygenase 1 contributes to inflammatory responses in rats and mice: implications for gastrointestinal toxicity.
Gastroenterology 1998;115(1):101-9.
1998: Vergnolle N; Macnaughton W K; Al-Ani B; Saifeddine M; Wallace J L; Hollenberg M D
Proteinase-activated receptor 2 (PAR2)-activating peptides: identification of a receptor distinct from PAR2 that regulates intestinal transport.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(13):7766-71.
1998: Wallace J L; McKnight W; Asfaha S; Liu D Y
Reduction of acute and reactivated colitis in rats by an inhibitor of neutrophil activation.
The American journal of physiology 1998;274(5 Pt 1):G802-8.
1998: Miampamba M; Parr E J; McCafferty D M; Wallace J L; Sharkey K A
Effect of intracolonic benzalkonium chloride on trinitrobenzene sulphonic acid-induced colitis in the rat.
Alimentary pharmacology & therapeutics 1998;12(3):219-28.
1998: Wallace J L; McCafferty D M; Sharkey K A
Lack of beneficial effect of a tachykinin receptor antagonist in experimental colitis.
Regulatory peptides 1998;73(2):95-101.
1998: Wallace J L; Reuter B K; McKnight W; Bak A
Selective inhibitors of cyclooxygenase-2: are they really effective, selective, and GI-safe?
Journal of clinical gastroenterology 1998;27 Suppl 1():S28-34.
1998: Bak A W; McKnight W; Li P; Del Soldato P; Calignano A; Cirino G; Wallace J L
Cyclooxygenase-independent chemoprevention with an aspirin derivative in a rat model of colonic adenocarcinoma.
Life sciences 1998;62(23):PL 367-73.
1998: Muscará M N; McKnight W; Del Soldato P; Wallace J L
Effect of a nitric oxide-releasing naproxen derivative on hypertension and gastric damage induced by chronic nitric oxide inhibition in the rat.
Life sciences 1998;62(15):PL235-40.
1998: Elliott S N; McKnight W; Davies N M; MacNaughton W K; Wallace J L
Alendronate induces gastric injury and delays ulcer healing in rodents.
Life sciences 1998;62(1):77-91.
1997: Davies N M; Sharkey K A; Asfaha S; Macnaughton W K; Wallace J L
Aspirin causes rapid up-regulation of cyclo-oxygenase-2 expression in the stomach of rats.
Alimentary pharmacology & therapeutics 1997;11(6):1101-8.
1997: Wallace J L; McKnight W; Wilson T L; Del Soldato P; Cirino G
Reduction of shock-induced gastric damage by a nitric oxide-releasing aspirin derivative: role of neutrophils.
The American journal of physiology 1997;273(6 Pt 1):G1246-51.
1997: Ferraz J G; Sharkey K A; Reuter B K; Asfaha S; Tigley A W; Brown M L; McKnight W; Wallace J L
Induction of cyclooxygenase 1 and 2 in the rat stomach during endotoxemia: role in resistance to damage.
Gastroenterology 1997;113(1):195-204.
1997: Ferraz J G; Tigley A W; Appleyard C B; Wallace J L
TNF-alpha contributes to the pathogenesis of ethanol-induced gastric damage in cirrhotic rats.
The American journal of physiology 1997;272(4 Pt 1):G809-14.
1997: Wallace J L
Nonsteroidal anti-inflammatory drugs and gastroenteropathy: the second hundred years.
Gastroenterology 1997;112(3):1000-16.
1997: McCafferty D M; Wallace J L; Sharkey K A
Effects of chemical sympathectomy and sensory nerve ablation on experimental colitis in the rat.
The American journal of physiology 1997;272(2 Pt 1):G272-80.
1997: Swain M G; Appleyard C B; Wallace J L; Maric M
TNF-alpha facilitates inflammation-induced glucocorticoid secretion in rats with biliary obstruction.
Journal of hepatology 1997;26(2):361-8.
1997: Davies N M; Wallace J L
Nonsteroidal anti-inflammatory drug-induced gastrointestinal toxicity: new insights into an old problem.
Journal of gastroenterology 1997;32(1):127-33.
1997: Davies N M; Røseth A G; Appleyard C B; McKnight W; Del Soldato P; Calignano A; Cirino G; Wallace J L
NO-naproxen vs. naproxen: ulcerogenic, analgesic and anti-inflammatory effects.
Alimentary pharmacology & therapeutics 1997;11(1):69-79.
1997: Reuter B K; Davies N M; Wallace J L
Nonsteroidal anti-inflammatory drug enteropathy in rats: role of permeability, bacteria, and enterohepatic circulation.
Gastroenterology 1997;112(1):109-17.
1997: Beck P L; Wallace J L
Cytokines in inflammatory bowel disease.
Mediators of inflammation 1997;6(2):95-103.
1996: Davies N M; Wallace J L
Selective inhibitors of cyclooxygenase-2. Potential in elderly patients.
Drugs & aging 1996;9(6):406-17.
1996: Rioux K P; Wallace J L
Long-term antigen challenge results in progressively diminished mucosal mast cell degranulation in rats.
Gastroenterology 1996;111(6):1516-23.
1996: Wallace J L
NSAID gastroenteropathy: past, present and future.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 1996;10(7):451-9.
1996: Reuter B K; Asfaha S; Buret A; Sharkey K A; Wallace J L
Exacerbation of inflammation-associated colonic injury in rat through inhibition of cyclooxygenase-2.
The Journal of clinical investigation 1996;98(9):2076-85.
1996: Wallace J L; Granger D N
The cellular and molecular basis of gastric mucosal defense.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1996;10(7):731-40.
1996: Cirino G; Wheeler-Jones C P; Wallace J L; Del Soldato P; Baydoun A R
Inhibition of inducible nitric oxide synthase expression by novel nonsteroidal anti-inflammatory derivatives with gastrointestinal-sparing properties.
British journal of pharmacology 1996;117(7):1421-6.
1996: Rioux K P; Wallace J L
Mast cells do not contribute to nonsteroidal anti-inflammatory drug-induced gastric mucosal injury in rodents.
Alimentary pharmacology & therapeutics 1996;10(2):173-80.
1996: Rioux K P; Sharkey K A; Wallace J L; Swain M G
Hepatic mucosal mast cell hyperplasia in rats with secondary biliary cirrhosis.
Hepatology (Baltimore, Md.) 1996;23(4):888-95.
1996: Appleyard C B; McCafferty D M; Tigley A W; Swain M G; Wallace J L
Tumor necrosis factor mediation of NSAID-induced gastric damage: role of leukocyte adherence.
The American journal of physiology 1996;270(1 Pt 1):G42-8.
1996: Geraldo J; Ferraz P; Wallace J L
Prostaglandins modulate the responsiveness of the gastric microcirculation of sodium nitroprusside in cirrhotic rats.
Hepatology (Baltimore, Md.) 1996;23(1):123-9.
1995: Wallace J L; McKnight W; Del Soldato P; Baydoun A R; Cirino G
Anti-thrombotic effects of a nitric oxide-releasing, gastric-sparing aspirin derivative.
The Journal of clinical investigation 1995;96(6):2711-8.
1995: McCafferty D M; Granger D N; Wallace J L
Indomethacin-induced gastric injury and leukocyte adherence in arthritic versus healthy rats.
Gastroenterology 1995;109(4):1173-80.
1995: Wallace J L; Le T; Carter L; Appleyard C B; Beck P L
Hapten-induced chronic colitis in the rat: alternatives to trinitrobenzene sulfonic acid.
Journal of pharmacological and toxicological methods 1995;33(4):237-9.
1995: Elliott S N; McKnight W; Cirino G; Wallace J L
A nitric oxide-releasing nonsteroidal anti-inflammatory drug accelerates gastric ulcer healing in rats.
Gastroenterology 1995;109(2):524-30.
1995: Appleyard C B; Wallace J L
Reactivation of hapten-induced colitis and its prevention by anti-inflammatory drugs.
The American journal of physiology 1995;269(1 Pt 1):G119-25.
1995: Cirino G; Cicala C; Mancuso F; Baydoun A R; Wallace J L
Flurbinitroxybutylester: a novel anti-inflammatory drug has enhanced antithrombotic activity.
Thrombosis research 1995;79(1):73-81.
1995: Wallace J L; Tigley A W
Review article: new insights into prostaglandins and mucosal defence.
Alimentary pharmacology & therapeutics 1995;9(3):227-35.
1995: Wallace J L; Cirino G; McKnight G W; Elliott S N
Reduction of gastrointestinal injury in acute endotoxic shock by flurbiprofen nitroxybutylester.
European journal of pharmacology 1995;280(1):63-8.
1995: Bell C J; Gall D G; Wallace J L
Disruption of colonic electrolyte transport in experimental colitis.
The American journal of physiology 1995;268(4 Pt 1):G622-30.
1995: Ferraz J G; McKnight W; Sharkey K A; Wallace J L
Impaired vasodilatory responses in the gastric microcirculation of anesthetized rats with secondary biliary cirrhosis.
Gastroenterology 1995;108(4):1183-91.
1995: Wallace J L; McKnight G W; Bell C J
Adaptation of rat gastric mucosa to aspirin requires mucosal contact.
The American journal of physiology 1995;268(1 Pt 1):G134-8.
1995: Carter L; Wallace J L
Alterations in rat peripheral blood neutrophil function as a consequence of colitis.
Digestive diseases and sciences 1995;40(1):192-7.
1995: Curtis G H; MacNaughton W K; Gall D G; Wallace J L
Intraluminal pH modulates gastric prostaglandin synthesis.
Canadian journal of physiology and pharmacology 1995;73(1):130-4.
1995: Wallace J L; Pittman Q J; Cirino G
Nitric oxide-releasing NSAIDs: a novel class of GI-sparing anti-inflammatory drugs.
Agents and actions. Supplements 1995;46():121-9.
1994: Wallace J L
The 1994 Merck Frosst Award. Mechanisms of nonsteroidal anti-inflammatory drug (NSAID) induced gastrointestinal damage--potential for development of gastrointestinal tract safe NSAIDs.
Canadian journal of physiology and pharmacology 1994;72(12):1493-8.
1994: Wallace J L; Carter L; McKnight W; Tries S; Laufer S
ML 3000 reduces gastric prostaglandin synthesis without causing mucosal injury.
European journal of pharmacology 1994;271(2-3):525-31.
1994: Wallace J L; Cirino G
The development of gastrointestinal-sparing nonsteroidal anti-inflammatory drugs.
Trends in pharmacological sciences 1994;15(11):405-6.
1994: Wallace J L; Reuter B; Cicala C; McKnight W; Grisham M B; Cirino G
Novel nonsteroidal anti-inflammatory drug derivatives with markedly reduced ulcerogenic properties in the rat.
Gastroenterology 1994;107(1):173-9.
1994: Ferraz J G; Tigley A; Wallace J L
Paradoxical effects of L-arginine on gastric mucosal integrity.
European journal of pharmacology 1994;260(1):107-11.
1994: Rioux K P; Wallace J L
Mast cell activation augments gastric mucosal injury through a leukotriene-dependent mechanism.
The American journal of physiology 1994;266(5 Pt 1):G863-9.
1994: Wallace J L; Reuter B; Cicala C; McKnight W; Grisham M; Cirino G
A diclofenac derivative without ulcerogenic properties.
European journal of pharmacology 1994;257(3):249-55.
1994: McCafferty D M; Sharkey K A; Wallace J L
Beneficial effects of local or systemic lidocaine in experimental colitis.
The American journal of physiology 1994;266(4 Pt 1):G560-7.
1994: Dias V C; Shaffer E A; Wallace J L; Parsons H G
Bile salts determine leukotriene B4 synthesis in a human intestinal cell line (CaCo-2).
Digestive diseases and sciences 1994;39(4):802-8.
1994: Sutherland L R; Verhoef M; Wallace J L; Van Rosendaal G; Crutcher R; Meddings J B
A simple, non-invasive marker of gastric damage: sucrose permeability.
Lancet 1994;343(8904):998-1000.
1994: Kanwar S; Wallace J L; Befus D; Kubes P
Nitric oxide synthesis inhibition increases epithelial permeability via mast cells.
The American journal of physiology 1994;266(2 Pt 1):G222-9.
1994: Hierlihy L E; Wallace J L; Ferguson A V
Autonomic pathways in development of neural stimulation-induced gastric mucosal damage.
The American journal of physiology 1994;266(2 Pt 1):G179-85.
1994: Reuter B K; Cirino G; Wallace J L
Markedly reduced intestinal toxicity of a diclofenac derivative.
Life sciences 1994;55(1):PL1-8.
1994: Wallace J L; Reuter B K; Cirino G
Nitric oxide-releasing non-steroidal anti-inflammatory drugs: a novel approach for reducing gastrointestinal toxicity.
Journal of gastroenterology and hepatology 1994;9 Suppl 1():S40-4.
1993: Wallace J L; McCafferty D M; Carter L; McKnight W; Argentieri D
Tissue-selective inhibition of prostaglandin synthesis in rat by tepoxalin: anti-inflammatory without gastropathy?
Gastroenterology 1993;105(6):1630-6.
1993: Beck P L; McKnight G W; Kelly J K; Wallace J L; Lee S S
Hepatic and gastric cytoprotective effects of long-term prostaglandin E1 administration in cirrhotic rats.
Gastroenterology 1993;105(5):1483-9.
1993: Wallace J L; McKnight W; Miyasaka M; Tamatani T; Paulson J; Anderson D C; Granger D N; Kubes P
Role of endothelial adhesion molecules in NSAID-induced gastric mucosal injury.
The American journal of physiology 1993;265(5 Pt 1):G993-8.
1993: Hogaboam C M; Befus A D; Wallace J L
Modulation of rat mast cell reactivity by IL-1 beta. Divergent effects on nitric oxide and platelet-activating factor release.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(7):3767-74.
1993: Hierlihy L E; Wallace J L; Ferguson A V
Role of gastric acid secretion and blood flow in the development of vagal stimulation induced gastric mucosal damage.
Canadian journal of physiology and pharmacology 1993;71(10-11):829-34.
1993: Beck P L; McKnight W; Lee S S; Wallace J L
Prostaglandin modulation of the gastric vasculature and mucosal integrity in cirrhotic rats.
The American journal of physiology 1993;265(3 Pt 1):G453-8.
1993: Higa A; McKnight G W; Wallace J L
Attenuation of epithelial injury in acute experimental colitis by immunomodulators.
European journal of pharmacology 1993;239(1-3):171-6.
1993: Bell C J; Wallace J L
Corticosteroid drugs and inflammation: the endothelial-leukocyte interface as a target for therapeutics.
Journal of pediatric gastroenterology and nutrition 1993;17(1):113-4.
1993: Wallace J L; McKnight G W
Characterization of a simple animal model for nonsteroidal anti-inflammatory drug induced antral ulcer.
Canadian journal of physiology and pharmacology 1993;71(7):447-52.
1993: Meddings J B; Sutherland L R; Byles N I; Wallace J L
Sucrose: a novel permeability marker for gastroduodenal disease.
Gastroenterology 1993;104(6):1619-26.
1993: Wallace J L; McKnight G W; Donigi-Gale D; Shoupe T S; Granger D N
Protective effects of PF-10040 in experimental NSAID-gastritis: role of leukocytes, leukotrienes and PAF.
Journal of lipid mediators 1993;7(2):183-96.
1993: McCafferty D M; Kubes P; Wallace J L
Inhibition of platelet-activating factor-induced leukocyte adhesion in vivo by a leumedin.
European journal of pharmacology 1993;232(2-3):169-72.
1993: Freedman S M; Wallace J L; Shaffer E A
Characterization of leukotriene-induced contraction of the guinea-pig gallbladder in vitro.
Canadian journal of physiology and pharmacology 1993;71(2):145-50.
1993: Wallace J L
Gastric ulceration: critical events at the neutrophil--endothelium interface.
Canadian journal of physiology and pharmacology 1993;71(1):98-102.
1993: Hogaboam C M; Bissonnette E Y; Chin B C; Befus A D; Wallace J L
Prostaglandins inhibit inflammatory mediator release from rat mast cells.
Gastroenterology 1993;104(1):122-9.
1992: Wallace J L; Rioux K P; McKnight W; Carter L; Jourd'heuil D; Meddings J; Zimmerman B J; Granger D N; Grisham M B
Hemoprotein-dependent production of a neutrophil-activating factor from arachidonic acid.
The American journal of physiology 1992;263(5 Pt 2):H1546-53.
1992: Wallace J L
Prostaglandins, NSAIDs, and cytoprotection.
Gastroenterology clinics of North America 1992;21(3):631-41.
1992: Beck P L; Lee S S; McKnight G W; Wallace J L
Characterization of spontaneous and ethanol-induced gastric damage in cirrhotic rats.
Gastroenterology 1992;103(3):1048-55.
1992: Parente L; Perretti M; Wallace J L; Mugridge K G
Mechanism of the protective action of interleukin-1 in the experimental gastric damage in the rat.
Pharmacological research : the official journal of the Italian Pharmacological Society 1992;26 Suppl 2():28-9.
1992: Wallace J L; McKnight G W; Befus A D
Capsaicin-induced hyperemia in the stomach: possible contribution of mast cells.
The American journal of physiology 1992;263(2 Pt 1):G209-14.
1992: Hierlihy L E; Wallace J L; Ferguson A V
Neurally mediated gastric mucosal damage in hypophysectomized rats.
Canadian journal of physiology and pharmacology 1992;70(8):1109-16.
1992: Wallace J L; Higa A; McKnight G W; MacIntyre D E
Prevention and reversal of experimental colitis by a monoclonal antibody which inhibits leukocyte adherence.
Inflammation 1992;16(4):343-54.
1992: Perretti M; Mugridge K G; Wallace J L; Parente L
Reduction of aspirin-induced gastric damage in rats by interleukin-1 beta: possible involvement of endogenous corticosteroids.
The Journal of pharmacology and experimental therapeutics 1992;261(3):1238-47.
1992: Hogaboam C M; Donigi-Gale D; Shoupe T S; Wallace J L
PF-5901 inhibits gastrointestinal platelet-activating factor synthesis in vivo.
European journal of pharmacology 1992;216(2):315-8.
1992: Vaananen P M; Keenan C M; Grisham M B; Wallace J L
Pharmacological investigation of the role of leukotrienes in the pathogenesis of experimental NSAID gastropathy.
Inflammation 1992;16(3):227-40.
1992: Dias V C; Wallace J L; Parsons H G
Modulation of cellular phospholipid fatty acids and leukotriene B4 synthesis in the human intestinal cell (CaCo-2).
Gut 1992;33(5):622-7.
1992: Wallace J L; Granger D N
Pathogenesis of NSAID gastropathy: are neutrophils the culprits?
Trends in pharmacological sciences 1992;13(4):129-31.
1992: Wallace J L; Keenan C M; Cucala M; Mugridge K G; Parente L
Mechanisms underlying the protective effects of interleukin 1 in experimental nonsteroidal anti-inflammatory drug gastropathy.
Gastroenterology 1992;102(4 Pt 1):1176-85.
1992: Hogaboam C M; Donigi-Gale D; Shoupe T S; Bissonnette E Y; Befus A D; Wallace J L
Platelet-activating factor synthesis by peritoneal mast cells and its inhibition by two quinoline-based compounds.
British journal of pharmacology 1992;105(1):87-92.
1992: Wallace J L; Keenan C M; Gale D; Shoupe T S
Exacerbation of experimental colitis by nonsteroidal anti-inflammatory drugs is not related to elevated leukotriene B4 synthesis.
Gastroenterology 1992;102(1):18-27.
1992: Freedman S M; Basu D K; Wallace J L; Shaffer E A
Leukotriene-induced contraction of isolated guinea pig gallbladder (GB) strips.
Advances in experimental medicine and biology 1992;311():437-8.
1992: Wallace J L; Hogaboam C M; Kubes P
Immunopathology of NSAID-gastropathy: inhibitory effects of interleukin-I and cyclosporin A.
Annals of the New York Academy of Sciences 1992;664():400-7.
1992: Wallace J L
Non-steroidal anti-inflammatory drug gastropathy and cytoprotection: pathogenesis and mechanisms re-examined.
Scandinavian journal of gastroenterology. Supplement 1992;192():3-8.
1992: McCafferty D M; Rioux K J; Wallace J L
Granulocyte infiltration in experimental colitis in the rat is interleukin-1 dependent and leukotriene independent.
Eicosanoids 1992;5(3-4):121-5.
1991: Bissonnette E Y; Hogaboam C M; Wallace J L; Befus A D
Potentiation of tumor necrosis factor-alpha-mediated cytotoxicity of mast cells by their production of nitric oxide.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(9):3060-5.
1991: Meddings J B; Hogaboam C M; Tran K; Reynolds J D; Wallace J L
Capsaicin effects on non-neuronal plasma membranes.
Biochimica et biophysica acta 1991;1070(1):43-50.
1991: Wallace J L; Cucala M; Mugridge K; Parente L
Secretagogue-specific effects of interleukin-1 on gastric acid secretion.
The American journal of physiology 1991;261(4 Pt 1):G559-64.
1991: Vaananen P M; Meddings J B; Wallace J L
Role of oxygen-derived free radicals in indomethacin-induced gastric injury.
The American journal of physiology 1991;261(3 Pt 1):G470-5.
1991: Wallace J L; Cirino G; Cicala C; Anderson D W; Argentieri D; Capetola R J
Comparison of the ulcerogenic properties of tepoxalin with those of non-steroidal anti-inflammatory drugs (NSAIDs).
Agents and actions 1991;34(1-2):247-50.
1991: Hogaboam C M; Wallace J L
Inhibition of platelet aggregation by capsaicin. An effect unrelated to actions on sensory afferent neurons.
European journal of pharmacology 1991;202(1):129-31.
1991: Hogaboam C M; Befus A D; Wallace J L
Intestinal platelet-activating factor synthesis during Nippostrongylus brasiliensis infection in the rat.
Journal of lipid mediators 1991;4(2):211-24.
1991: Hierlihy L E; Wallace J L; Ferguson A V
Vagal stimulation-induced gastric damage in rats.
The American journal of physiology 1991;261(1 Pt 1):G104-10.
1991: Wallace J L; Arfors K E; McKnight G W
A monoclonal antibody against the CD18 leukocyte adhesion molecule prevents indomethacin-induced gastric damage in the rabbit.
Gastroenterology 1991;100(4):878-83.
1991: Wallace J L
Possible mechanisms and mediators of gastritis associated with Helicobacter pylori infection.
Scandinavian journal of gastroenterology. Supplement 1991;187():65-70.
1990: Wallace J L; Keenan C M; Mugridge K G; Parente L
Reduction of the severity of experimental gastric and duodenal ulceration by interleukin-1 beta.
European journal of pharmacology 1990;186(2-3):279-84.
1990: Mathison R; Rimmer C; Davison J S; Wallace J L; Befus A D
Alterations in regional blood flow in rats following sensitization to the nematode Nippostrongylus brasiliensis: effects of PAF antagonists.
British journal of pharmacology 1990;101(1):93-6.
1990: Wallace J L; Keenan C M; Granger D N
Gastric ulceration induced by nonsteroidal anti-inflammatory drugs is a neutrophil-dependent process.
The American journal of physiology 1990;259(3 Pt 1):G462-7.
1990: Wallace J L; McKnight G W
The mucoid cap over superficial gastric damage in the rat. A high-pH microenvironment dissipated by nonsteroidal antiinflammatory drugs and endothelin.
Gastroenterology 1990;99(2):295-304.
1990: Wallace J L; Hogaboam C M; McKnight G W
Platelet-activating factor mediates gastric damage induced by hemorrhagic shock.
The American journal of physiology 1990;259(1 Pt 1):G140-6.
1990: Wallace J L; McKnight G W
Comparison of the damage-promoting effects of leukotrienes derived from eicosapentaenoic acid and arachidonic acid on the rat stomach.
The Journal of experimental medicine 1990;171(5):1827-32.
1990: Wallace J L; Keenan C M
Leukotriene B4 potentiates colonic ulceration in the rat.
Digestive diseases and sciences 1990;35(5):622-9.
1990: Wallace J L; McKnight G W; Keenan C M; Byles N I; MacNaughton W K
Effects of leukotrienes on susceptibility of the rat stomach to damage and investigation of the mechanism of action.
Gastroenterology 1990;98(5 Pt 1):1178-86.
1990: Wallace J L; Keenan C M
An orally active inhibitor of leukotriene synthesis accelerates healing in a rat model of colitis.
The American journal of physiology 1990;258(4 Pt 1):G527-34.
1990: Wallace J L
Mucosal defense. New avenues for treatment of ulcer disease?
Gastroenterology clinics of North America 1990;19(1):87-100.
1990: Wallace J L
5-Lipoxygenase: a rational target for therapy of inflammatory bowel disease?
Trends in pharmacological sciences 1990;11(2):51-3.
1990: Wallace J L
Lipid mediators of inflammation in gastric ulcer.
The American journal of physiology 1990;258(1 Pt 1):G1-11.
1989: Guarner F; Wallace J L; MacNaughton W K; Ibbotson G C; Arroyo V; Rodés J
Endotoxin-induced ascites formation in the rat: partial mediation by platelet-activating factor.
Hepatology (Baltimore, Md.) 1989;10(5):788-94.
1989: Ibbotson G C; Wallace J L
Inhibitory effects of dexamethasone in endotoxic shock and its relation to PAF-acether synthesis in the gastrointestinal tract and lung.
Journal of lipid mediators 1989;1(5):273-82.
1989: Wallace J L; Keenan C M; MacNaughton W K; McKnight G W
Comparison of the effects of endothelin-1 and endothelin-3 on the rat stomach.
European journal of pharmacology 1989;167(1):41-7.
1989: Morris G P; Keenan C M; MacNaughton W K; Wallace J L; Williamson T E
Protection of rat gastric mucosa by sucralfate. Effects of luminal stasis and of inhibition of prostaglandins synthesis.
The American journal of medicine 1989;86(6A):10-6.
1989: Wallace J L; Cirino G; De Nucci G; McKnight W; MacNaughton W K
Endothelin has potent ulcerogenic and vasoconstrictor actions in the stomach.
The American journal of physiology 1989;256(4 Pt 1):G661-6.
1989: MacNaughton W K; Wallace J L
A role for dopamine as an endogenous protective factor in the rat stomach.
Gastroenterology 1989;96(4):972-80.
1989: Beck P L; Morris G P; Wallace J L
Reduction of ethanol-induced gastric damage by sodium cromoglycate and FPL-52694. Role of leukotrienes, prostaglandins, and mast cells in the protective mechanism.
Canadian journal of physiology and pharmacology 1989;67(4):287-93.
1989: Morris G P; Beck P L; Herridge M S; Depew W T; Szewczuk M R; Wallace J L
Hapten-induced model of chronic inflammation and ulceration in the rat colon.
Gastroenterology 1989;96(3):795-803.
1989: Ibbotson G C; Wallace J L
Beneficial effects of prostaglandin E2 in endotoxic shock are unrelated to effects on PAF-acether synthesis.
Prostaglandins 1989;37(2):237-50.
1989: Wallace J L; MacNaughton W K; Morris G P; Beck P L
Inhibition of leukotriene synthesis markedly accelerates healing in a rat model of inflammatory bowel disease.
Gastroenterology 1989;96(1):29-36.
1989: Wallace J L; Braquet P; Ibbotson G C; MacNaughton W K; Cirino G
Assessment of the role of platelet-activating factor in an animal model of inflammatory bowel disease.
Journal of lipid mediators 1989;1(1):13-23.
1989: Wallace J L
Gastric resistance to acid: is the "mucus-bicarbonate barrier" functionally redundant?
The American journal of physiology 1989;256(1 Pt 1):G31-8.
1989: Wallace J L
Extracellular mucus and repair of superficial mucosal injury by restitution.
Methods and findings in experimental and clinical pharmacology 1989;11 Suppl 1():27-33.
1989: MacNaughton W K; Cirino G; Wallace J L
Endothelium-derived relaxing factor (nitric oxide) has protective actions in the stomach.
Life sciences 1989;45(20):1869-76.
1989: MacNaughton W K; Keenan C M; McKnight G W; Wallace J L
The modulation of gastric mucosal integrity by endothelin-1 and prostacyclin.
Journal of cardiovascular pharmacology 1989;13 Suppl 5():S118-22; discussion S123.
1988: Ferguson A V; Marcus P; Spencer J; Wallace J L
Paraventricular nucleus stimulation causes gastroduodenal mucosal necrosis in the rat.
The American journal of physiology 1988;255(5 Pt 2):R861-5.
1988: Wallace J L; MacNaughton W K
Gastrointestinal damage induced by platelet-activating factor: role of leukotrienes.
European journal of pharmacology 1988;151(1):43-50.
1988: Wallace J L; Morris G P; Beck P L; Williamson T E; Gingras G R
Effects of sucralfate on gastric prostaglandin and leukotriene synthesis: relationship to protective actions.
Canadian journal of physiology and pharmacology 1988;66(5):666-70.
1988: Wallace J L
Release of platelet-activating factor (PAF) and accelerated healing induced by a PAF antagonist in an animal model of chronic colitis.
Canadian journal of physiology and pharmacology 1988;66(4):422-5.
1988: Wallace J L; Beck P L; Morris G P
Is there a role for leukotrienes as mediators of ethanol-induced gastric mucosal damage?
The American journal of physiology 1988;254(1 Pt 1):G117-23.
1988: Wallace J L
Increased resistance of the rat gastric mucosa to hemorrhagic damage after exposure to an irritant. Role of the "mucoid cap" and prostaglandin synthesis.
Gastroenterology 1988;94(1):22-32.
1987: Wallace J L
Glucocorticoid-induced gastric mucosal damage: inhibition of leukotriene, but not prostaglandin biosynthesis.
Prostaglandins 1987;34(2):311-23.
1987: Wallace J L; Steel G; Whittle B J
Gastrointestinal plasma leakage in endotoxic shock. Inhibition by prostaglandin E2 and by a platelet-activating factor antagonist.
Canadian journal of physiology and pharmacology 1987;65(7):1428-32.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

John Wallace

Research Profile (preview)

Living Beings

Anatomy

Chemicals & Drugs

Disorders

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of John Wallace (preview)

All Publications