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Kristina Walle
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80
Walle, Thomas
7
Bai, Stephen
6
Otake, Yoko
5
Galijatovic, A
4
McMillan, JoEllyn
3
Oatis, John
3
Oexmann, MJ
3
Bhalla, Kapil
3
Wen, Xia
2
Webb, Jerry
2
Knapp, Daniel
2
Walgren, Richard
2
Halushka, Perry
2
Boulton, David
1
Kawamori, Toshihiko
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All Publications
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2007: Walle U Kristina; Walle Thomas
Bioavailable flavonoids: cytochrome P450-mediated metabolism of methoxyflavones.
Drug metabolism and disposition: the biological fate of chemicals 2007;35(11):1985-9.
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2007: Walle Thomas; Walle U Kristina
Novel methoxylated flavone inhibitors of cytochrome P450 1B1 in SCC-9 human oral cancer cells.
The Journal of pharmacy and pharmacology 2007;59(6):857-62.
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2007: Walle Thomas; Wen Xia; Walle U Kristina
Improving metabolic stability of cancer chemoprotective polyphenols.
Expert opinion on drug metabolism & toxicology 2007;3(3):379-88.
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2007: Walle Thomas; Ta Nga; Kawamori Toshihiko; Wen Xia; Tsuji Petra A; Walle U Kristina
Cancer chemopreventive properties of orally bioavailable flavonoids--methylated versus unmethylated flavones.
Biochemical pharmacology 2007;73(9):1288-96.
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2006: Walle Thomas; Walle U Kristina; Sedmera David; Klausner Mitch
Benzo[A]pyrene-induced oral carcinogenesis and chemoprevention: studies in bioengineered human tissue.
Drug metabolism and disposition: the biological fate of chemicals 2006;34(3):346-50.
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2005: Browning Alyson M; Walle U Kristina; Walle Thomas
Flavonoid glycosides inhibit oral cancer cell proliferation--role of cellular uptake and hydrolysis to the aglycones.
The Journal of pharmacy and pharmacology 2005;57(8):1037-42.
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2005: McMillan J M; Walle U K; Walle T
S-adenosyl-L-methionine: transcellular transport and uptake by Caco-2 cells and hepatocytes.
The Journal of pharmacy and pharmacology 2005;57(5):599-605.
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2005: Kaldas Mark I; Walle U Kristina; van der Woude Hester; McMillan JoEllyn M; Walle Thomas
Covalent binding of the flavonoid quercetin to human serum albumin.
Journal of agricultural and food chemistry 2005;53(10):4194-7.
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2005: Wen Xia; Walle U Kristina; Walle Thomas
5,7-Dimethoxyflavone downregulates CYP1A1 expression and benzo[a]pyrene-induced DNA binding in Hep G2 cells.
Carcinogenesis 2005;26(4):803-9.
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2005: Walle Thomas; Browning Alyson M; Steed Lisa L; Reed Susan G; Walle U Kristina
Flavonoid glucosides are hydrolyzed and thus activated in the oral cavity in humans.
The Journal of nutrition 2005;135(1):48-52.
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2004: Walle Thomas; Hsieh Faye; DeLegge Mark H; Oatis John E; Walle U Kristina
High absorption but very low bioavailability of oral resveratrol in humans.
Drug metabolism and disposition: the biological fate of chemicals 2004;32(12):1377-82.
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2003: Walle Thomas; Walle U Kristina
The beta-D-glucoside and sodium-dependent glucose transporter 1 (SGLT1)-inhibitor phloridzin is transported by both SGLT1 and multidrug resistance-associated proteins 1/2.
Drug metabolism and disposition: the biological fate of chemicals 2003;31(11):1288-91.
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2003: Walle Thomas; Vincent Timothy S; Walle U Kristina
Evidence of covalent binding of the dietary flavonoid quercetin to DNA and protein in human intestinal and hepatic cells.
Biochemical pharmacology 2003;65(10):1603-10.
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2003: Kaldas Mark I; Walle U Kristina; Walle Thomas
Resveratrol transport and metabolism by human intestinal Caco-2 cells.
The Journal of pharmacy and pharmacology 2003;55(3):307-12.
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2002: Walle U Kristina; Walle Thomas
Induction of human UDP-glucuronosyltransferase UGT1A1 by flavonoids-structural requirements.
Drug metabolism and disposition: the biological fate of chemicals 2002;30(5):564-9.
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2001: Walle T; Walle U K; Halushka P V
Carbon dioxide is the major metabolite of quercetin in humans.
The Journal of nutrition 2001;131(10):2648-52.
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2001: Galijatovic A; Otake Y; Walle U K; Walle T
Induction of UDP-glucuronosyltransferase UGT1A1 by the flavonoid chrysin in Caco-2 cells--potential role in carcinogen bioinactivation.
Pharmaceutical research 2001;18(3):374-9.
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2001: Walle T; Otake Y; Brubaker J A; Walle U K; Halushka P V
Disposition and metabolism of the flavonoid chrysin in normal volunteers.
British journal of clinical pharmacology 2001;51(2):143-6.
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2000: Walle T; Otake Y; Walle U K; Wilson F A
Quercetin glucosides are completely hydrolyzed in ileostomy patients before absorption.
The Journal of nutrition 2000;130(11):2658-61.
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2000: Walle T; Otake Y; Galijatovic A; Ritter J K; Walle U K
Induction of UDP-glucuronosyltransferase UGT1A1 by the flavonoid chrysin in the human hepatoma cell line hep G2.
Drug metabolism and disposition: the biological fate of chemicals 2000;28(9):1077-82.
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2000: Otake Y; Nolan A L; Walle U K; Walle T
Quercetin and resveratrol potently reduce estrogen sulfotransferase activity in normal human mammary epithelial cells.
The Journal of steroid biochemistry and molecular biology 2000;73(5):265-70.
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2000: Lewis A J; Otake Y; Walle U K; Walle T
Sulphonation of N-hydroxy-2-acetylaminofluorene by human dehydroepiandrosterone sulphotransferase.
Xenobiotica; the fate of foreign compounds in biological systems 2000;30(3):253-61.
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2000: Galijatovic A; Walle U K; Walle T
Induction of UDP-glucuronosyltransferase by the flavonoids chrysin and quercetin in Caco-2 cells.
Pharmaceutical research 2000;17(1):21-6.
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1999: Galijatovic A; Otake Y; Walle U K; Walle T
Extensive metabolism of the flavonoid chrysin by human Caco-2 and Hep G2 cells.
Xenobiotica; the fate of foreign compounds in biological systems 1999;29(12):1241-56.
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1999: Walle U K; Walle T
Transport of the cooked-food mutagen 2-amino-1-methyl-6-phenylimidazo-[4,5-b]pyridine (PhIP) across the human intestinal Caco-2 cell monolayer: role of efflux pumps.
Carcinogenesis 1999;20(11):2153-7.
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1999: Walle U K; Galijatovic A; Walle T
Transport of the flavonoid chrysin and its conjugated metabolites by the human intestinal cell line Caco-2.
Biochemical pharmacology 1999;58(3):431-8.
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1999: Bhalla K N; Kumar G N; Walle U K; Ibrado A M; Javed T; Stuart R K; Reed C; Arbuck S G; Walle T
Phase I and pharmacologic study of a 3-hour infusion of paclitaxel followed by cisplatinum and 5-fluorouracil in patients with advanced solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(7):1723-30.
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1999: Boulton D W; Walle U K; Walle T
Fate of the flavonoid quercetin in human cell lines: chemical instability and metabolism.
The Journal of pharmacy and pharmacology 1999;51(3):353-9.
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1999: Walle U K; French K L; Walgren R A; Walle T
Transport of genistein-7-glucoside by human intestinal CACO-2 cells: potential role for MRP2.
Research communications in molecular pathology and pharmacology 1999;103(1):45-56.
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1998: Lewis A J; Walle U K; King R S; Kadlubar F F; Falany C N; Walle T
Bioactivation of the cooked food mutagen N-hydroxy-2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by estrogen sulfotransferase in cultured human mammary epithelial cells.
Carcinogenesis 1998;19(11):2049-53.
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1998: Walgren R A; Walle U K; Walle T
Transport of quercetin and its glucosides across human intestinal epithelial Caco-2 cells.
Biochemical pharmacology 1998;55(10):1721-7.
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1998: Walle U K; Walle T
Taxol transport by human intestinal epithelial Caco-2 cells.
Drug metabolism and disposition: the biological fate of chemicals 1998;26(4):343-6.
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1998: Boulton D W; Walle U K; Walle T
Extensive binding of the bioflavonoid quercetin to human plasma proteins.
The Journal of pharmacy and pharmacology 1998;50(2):243-9.
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1996: Lewis A J; Kelly M M; Walle U K; Eaton E A; Falany C N; Walle T
Improved bacterial expression of the human P form phenolsulfotransferase. Applications to drug metabolism.
Drug metabolism and disposition: the biological fate of chemicals 1996;24(11):1180-5.
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1996: Walle T; Fagan T C; Walle U K; Topmiller M J
Stimulatory as well as inhibitory effects of ethinyloestradiol on the metabolic clearances of propranolol in young women.
British journal of clinical pharmacology 1996;41(4):305-9.
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1996: Eaton E A; Walle U K; Wilson H M; Aberg G; Walle T
Stereoselective sulphate conjugation of salbutamol by human lung and bronchial epithelial cells.
British journal of clinical pharmacology 1996;41(3):201-6.
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1996: Eaton E A; Walle U K; Lewis A J; Hudson T; Wilson A A; Walle T
Flavonoids, potent inhibitors of the human P-form phenolsulfotransferase. Potential role in drug metabolism and chemoprevention.
Drug metabolism and disposition: the biological fate of chemicals 1996;24(2):232-7.
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1996: Walle T; Eaton E A; Walle U K; Pesola G R
Stereoselective metabolism of RS-albuterol in humans.
Clinical reviews in allergy & immunology 1996;14(1):101-13.
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1995: Anderson C D; Wang J; Kumar G N; McMillan J M; Walle U K; Walle T
Dexamethasone induction of taxol metabolism in the rat.
Drug metabolism and disposition: the biological fate of chemicals 1995;23(11):1286-90.
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1995: Walle T; Eaton E A; Walle U K
Quercetin, a potent and specific inhibitor of the human P-form phenosulfotransferase.
Biochemical pharmacology 1995;50(5):731-4.
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1995: Walle T; Walle U K; Kumar G N; Bhalla K N
Taxol metabolism and disposition in cancer patients.
Drug metabolism and disposition: the biological fate of chemicals 1995;23(4):506-12.
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1994: Walle T; Walle U K; Shwed J A; Thornburg K R; Mathis C E; Pesola G R
Human phenol sulfotransferases: chiral substrates and expression in Hep G2 cells.
Chemico-biological interactions 1994;92(1-3):47-55.
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1994: Kumar G N; Walle U K; Walle T
Cytochrome P450 3A-mediated human liver microsomal taxol 6 alpha-hydroxylation.
The Journal of pharmacology and experimental therapeutics 1994;268(3):1160-5.
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1994: Walle U K; Fagan T C; Topmiller M J; Conradi E C; Walle T
The influence of gender and sex steroid hormones on the plasma binding of propranolol enantiomers.
British journal of clinical pharmacology 1994;37(1):21-5.
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1993: Walle T; Kumar G N; McMillan J M; Thornburg K R; Walle U K
Taxol metabolism in rat hepatocytes.
Biochemical pharmacology 1993;46(9):1661-4.
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1993: Kumar G N; Walle U K; Bhalla K N; Walle T
Binding of taxol to human plasma, albumin and alpha 1-acid glycoprotein.
Research communications in chemical pathology and pharmacology 1993;80(3):337-44.
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1993: Walle U K; Pesola G R; Walle T
Stereoselective sulphate conjugation of salbutamol in humans: comparison of hepatic, intestinal and platelet activity.
British journal of clinical pharmacology 1993;35(4):413-8.
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1993: Walle T; Walle U K; Thornburg K R; Schey K L
Stereoselective sulfation of albuterol in humans. Biosynthesis of the sulfate conjugate by HEP G2 cells.
Drug metabolism and disposition: the biological fate of chemicals 1993;21(1):76-80.
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1992: Shwed J A; Walle U K; Walle T
Hep G2 cell line as a human model for sulphate conjugation of drugs.
Xenobiotica; the fate of foreign compounds in biological systems 1992;22(8):973-82.
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1992: Steiner A; Walle U K; Walle T
Induction of propranolol metabolism in the Hep G2 human hepatoma cell line.
The Journal of pharmacy and pharmacology 1992;44(7):611-4.
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1992: Walle T; Walle U K
Stereoselective sulfate conjugation of 4-hydroxypropranolol and terbutaline by the human liver phenolsulfotransferases.
Drug metabolism and disposition: the biological fate of chemicals 1992;20(2):333-6.
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1991: Walle U K; Walle T
Stereoselective sulfate conjugation of 4-hydroxypropranolol in humans: comparison of platelet and hepatic activity.
Drug metabolism and disposition: the biological fate of chemicals 1991;19(4):838-40.
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1991: Walle T; Walle U K
Stereoselective sulfate conjugation of racemic 4-hydroxypropranolol by human and rat liver cytosol.
Drug metabolism and disposition: the biological fate of chemicals 1991;19(2):448-53.
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1991: Walle T; Webb J G; Walle U K; Bagwell E E
Stereoselective accumulation of the beta-receptor blocking drug atenolol by human platelets.
Chirality 1991;3(6):451-3.
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1990: Walle T; Walle U K
Stereoselective sulphate conjugation of racemic terbutaline by human liver cytosol.
British journal of clinical pharmacology 1990;30(1):127-33.
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1990: Walle T; Walle U K; Cowart T D; Conradi E C; Gaffney T E
Pharmacokinetics and metabolism of oral doses of a 4'-methylthio derivative of propranolol in man.
Xenobiotica; the fate of foreign compounds in biological systems 1990;20(3):321-31.
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1990: Christ D D; Walle U K; Oatis J E; Walle T
Pharmacokinetics and metabolism of the pharmacologically active 4'-hydroxylated metabolite of propranolol in the dog.
Drug metabolism and disposition: the biological fate of chemicals 1990;18(1):1-4.
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1989: Walle T; Walle U K; Cowart T D; Conradi E C
Pathway-selective sex differences in the metabolic clearance of propranolol in human subjects.
Clinical pharmacology and therapeutics 1989;46(3):257-63.
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1989: Bai S A; Easterling D E; Wilson M J; Walle U K; Haney C A; Peet N P; Pruett J K; Walle T
Pharmacokinetics and metabolism of a 4'-methylthio derivative of propranolol in the dog.
Drug metabolism and disposition: the biological fate of chemicals 1989;17(5):495-505.
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1989: Walle U K; Thibodeaux H; Privitera P J; Walle T
Stereochemistry of tissue distribution of racemic propranolol in the dog.
Chirality 1989;1(3):192-6.
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1989: Walle U K; Walle T
Stereoselective sulfation of terbutaline by the rat liver cytosol: evaluation of experimental approaches.
Chirality 1989;1(2):121-6.
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1988: Walle T; Webb J G; Bagwell E E; Walle U K; Daniell H B; Gaffney T E
Stereoselective delivery and actions of beta receptor antagonists.
Biochemical pharmacology 1988;37(1):115-24.
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1987: Walle T; Walle U K; Cowart T D; Conradi E C; Gaffney T E
Selective induction of propranolol metabolism by smoking: additional effects on renal clearance of metabolites.
The Journal of pharmacology and experimental therapeutics 1987;241(3):928-33.
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1987: Fagan T C; Walle T; Oexmann M J; Walle U K; Bai S A; Gaffney T E
Increased clearance of propranolol and theophylline by high-protein compared with high-carbohydrate diet.
Clinical pharmacology and therapeutics 1987;41(4):402-6.
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1986: Olanoff L S; Walle T; Cowart T D; Walle U K; Oexmann M J; Conradi E C
Food effects on propranolol systemic and oral clearance: support for a blood flow hypothesis.
Clinical pharmacology and therapeutics 1986;40(4):408-14.
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1986: Walle T; Walle U K; Olanoff L S; Conradi E C
Partial metabolic clearances as determinants of the oral bioavailability of propranolol.
British journal of clinical pharmacology 1986;22(3):317-23.
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1985: Walle T; Walle U K; Olanoff L S
Quantitative account of propranolol metabolism in urine of normal man.
Drug metabolism and disposition: the biological fate of chemicals 1985;13(2):204-9.
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1984: Walle T; Walle U K; Wilson M J; Fagan T C; Gaffney T E
Stereoselective ring oxidation of propranolol in man.
British journal of clinical pharmacology 1984;18(5):741-8.
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1984: Olanoff L S; Walle T; Walle U K; Cowart T D; Gaffney T E
Stereoselective clearance and distribution of intravenous propranolol.
Clinical pharmacology and therapeutics 1984;35(6):755-61.
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1983: Walle U K; Walle T; Bai S A; Olanoff L S
Stereoselective binding of propranolol to human plasma, alpha 1-acid glycoprotein, and albumin.
Clinical pharmacology and therapeutics 1983;34(6):718-23.
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1983: Bai S A; Wilson M J; Walle U K; Walle T
Stereoselective increase in propranolol bioavailability during chronic dosing in the dog.
The Journal of pharmacology and experimental therapeutics 1983;227(2):360-4.
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1983: Walle T; Wilson M J; Walle U K; Bai S A
Stereochemical composition of propranolol metabolites in the dog using stable isotope-labeled pseudoracemates.
Drug metabolism and disposition: the biological fate of chemicals 1983;11(6):544-9.
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1983: Bai S A; Walle U K; Wilson M J; Walle T
Stereoselective binding of the (-)-enantiomer of propranolol to plasma and extravascular binding sites in the dog.
Drug metabolism and disposition: the biological fate of chemicals 1983;11(4):394-5.
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1983: Walle T; Walle U K; Knapp D R; Conradi E C; Bargar E M
Identification of major sulfate conjugates in the metabolism of propranolol in dog and man.
Drug metabolism and disposition: the biological fate of chemicals 1983;11(4):344-9.
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1983: Bargar E M; Walle U K; Bai S A; Walle T
Quantitative metabolic fate of propranolol in the dog, rat, and hamster using radiotracer, high performance liquid chromatography, and gas chromatography-mass spectrometry techniques.
Drug metabolism and disposition: the biological fate of chemicals 1983;11(3):266-72.
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1982: Fagan T C; Walle T; Walle U K; Conradi E C; Harmon G; Gaffney T E
Early kinetics of intravenous propranolol.
British journal of clinical pharmacology 1982;13(4):571-4.
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1982: Walle T; Oatis J E; Walle U K; Knapp D R
New ring-hydroxylated metabolites of propranolol: species differences and stereospecific 7-hydroxylation.
Drug metabolism and disposition: the biological fate of chemicals 1982;10(2):122-7.
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1981: Walle T; Fagan T C; Walle U K; Oexmann M J; Conradi E C; Gaffney T E
Food-induced increase in propranolol bioavailability--relationship to protein and effects on metabolites.
Clinical pharmacology and therapeutics 1981;30(6):790-5.
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1980: Pruett J K; Walle T; Walle U K
Propranolol effects on membrane repolarization time in isolated canine Purkinje fibers: threshold tissue content and the influence of exposure time.
The Journal of pharmacology and experimental therapeutics 1980;215(2):539-43.
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1980: Walle T; Conradi E C; Walle U K; Fagan T C; Gaffney T E
4-Hydroxypropranolol and its glucuronide after single and long-term doses of propranolol.
Clinical pharmacology and therapeutics 1980;27(1):22-31.
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