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Peter Walsh

Research Profile

Chemicals & Drugs

Anatomy

Blood Platelets

Concepts & Ideas

Physiology

Genes & Molecular Sequences

Amino Acid Sequences

Phenomena

Protein Binding

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Publications

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Duraiswamy Navaneetham; Dipali Sinha; Ronald F Tuma; Hongbo Li; Wenman Wu; Peter N Walsh
P1 and P2' site mutations convert protease nexin-2 from a factor XIa inhibitor to a plasmin inhibitor.
Wenman Wu; Hongbo Li; Duraiswamy Navaneetham; Zachary W Reichenbach; Ronald F Tuma; Peter N Walsh
The kunitz protease inhibitor domain of protease nexin-2 inhibits factor XIa and murine carotid artery and middle cerebral artery thrombosis.
Ya-Chi Su; Tara N Miller; Duraiswamy Navaneetham; Robert T Schoonmaker; Dipali Sinha; Peter N Walsh
The role of factor XIa (FXIa) catalytic domain exosite residues in substrate catalysis and inhibition by the Kunitz protease inhibitor domain of protease nexin 2.

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All Publications

2013: Duraiswamy Navaneetham; Dipali Sinha; Ronald F Tuma; Hongbo Li; Wenman Wu; Peter N Walsh
P1 and P2' site mutations convert protease nexin-2 from a factor XIa inhibitor to a plasmin inhibitor.
Journal of biochemistry 2013;153(2):221-31.
2012: Wenman Wu; Hongbo Li; Duraiswamy Navaneetham; Zachary W Reichenbach; Ronald F Tuma; Peter N Walsh
The kunitz protease inhibitor domain of protease nexin-2 inhibits factor XIa and murine carotid artery and middle cerebral artery thrombosis.
Blood 2012;120(3):671-7.
2011: Ya-Chi Su; Tara N Miller; Duraiswamy Navaneetham; Robert T Schoonmaker; Dipali Sinha; Peter N Walsh
The role of factor XIa (FXIa) catalytic domain exosite residues in substrate catalysis and inhibition by the Kunitz protease inhibitor domain of protease nexin 2.
The Journal of biological chemistry 2011;286(36):31904-14.
2010: Moh'd A Salameh; Alexei S Soares; Duraiswamy Navaneetham; Dipali Sinha; Peter N Walsh; Evette S Radisky
Determinants of affinity and proteolytic stability in interactions of Kunitz family protease inhibitors with mesotrypsin.
The Journal of biological chemistry 2010;285(47):36884-96.
2010: Duraiswamy Navaneetham; Dipali Sinha; Peter N Walsh
Mechanisms and specificity of factor XIa and trypsin inhibition by protease nexin 2 and basic pancreatic trypsin inhibitor.
Journal of biochemistry 2010;148(4):467-79.
2010: Moh'd A Salameh; Jessica L Robinson; Duraiswamy Navaneetham; Dipali Sinha; Benjamin J Madden; Peter N Walsh; Evette S Radisky
The amyloid precursor protein/protease nexin 2 Kunitz inhibitor domain is a highly specific substrate of mesotrypsin.
The Journal of biological chemistry 2010;285(3):1939-49.
2009: Dmitri V Kravtsov; Anton Matafonov; Erik Tucker; Mao-Fu Sun; Peter N Walsh; Andras Gruber; David Gailani
Factor XI contributes to thrombin generation in the absence of factor XII.
Blood 2009;114(2):452-8.
2008: Wenman Wu; Dipali Sinha; Sergei Shikov; Calvin K Yip; Thomas Walz; Paul C Billings; James D Lear; Peter N Walsh
Factor XI homodimer structure is essential for normal proteolytic activation by factor XIIa, thrombin, and factor XIa.
The Journal of biological chemistry 2008;283(27):18655-64.
2007: Tara N Miller; Dipali Sinha; T Regan Baird; Peter N Walsh
A catalytic domain exosite (Cys527-Cys542) in factor XIa mediates binding to a site on activated platelets.
Biochemistry 2007;46(50):14450-60.
2007: Dharmaraj Samuel; Hong Cheng; Paul W Riley; Adrian A Canutescu; Chandrasekaran Nagaswami; John W Weisel; Zimei Bu; Peter N Walsh; Heinrich Roder
Solution structure of the A4 domain of factor XI sheds light on the mechanism of zymogen activation.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(40):15693-8.
2007: Dipali Sinha; Mariola Marcinkiewicz; Duraiswamy Navaneetham; Peter N Walsh
Macromolecular substrate-binding exosites on both the heavy and light chains of factor XIa mediate the formation of the Michaelis complex required for factor IX-activation.
Biochemistry 2007;46(34):9830-9.
2007: Paul W Riley; Hong Cheng; Dharmaraj Samuel; Heinrich Roder; Peter N Walsh
Dimer dissociation and unfolding mechanism of coagulation factor XI apple 4 domain: spectroscopic and mutational analysis.
Journal of molecular biology 2007;367(2):558-73.
2006: Fredda S London; Mariola Marcinkiewicz; Peter N Walsh
PAR-1-stimulated factor IXa binding to a small platelet subpopulation requires a pronounced and sustained increase of cytoplasmic calcium.
Biochemistry 2006;45(23):7289-98.
2006: Evangelos Papagrigoriou; Paul A McEwan; Peter N Walsh; Jonas Emsley
Crystal structure of the factor XI zymogen reveals a pathway for transactivation.
Nature structural & molecular biology 2006;13(6):557-8.
2005: Duraiswamy Navaneetham; Lei Jin; Pramod Pandey; James E Strickler; Robert E Babine; Sherin S Abdel-Meguid; Peter N Walsh
Structural and mutational analyses of the molecular interactions between the catalytic domain of factor XIa and the Kunitz protease inhibitor domain of protease nexin 2.
The Journal of biological chemistry 2005;280(43):36165-75.
2005: Syed S Ahmad; Peter N Walsh
Role of the C2 domain of factor VIIIa in the assembly of factor-X activating complex on the platelet membrane.
Biochemistry 2005;44(42):13858-65.
2005: Xia Yang; Peter N Walsh
An ordered sequential mechanism for Factor IX and Factor IXa binding to platelet receptors in the assembly of the Factor X-activating complex.
The Biochemical journal 2005;390(Pt 1):157-67.
2005: Dipali Sinha; Mariola Marcinkiewicz; James D Lear; Peter N Walsh
Factor XIa dimer in the activation of factor IX.
Biochemistry 2005;44(30):10416-22.
2005: Hironao Wakabayashi; Ya-Chi Su; Syed S Ahmad; Peter N Walsh; Philip J Fay
A Glu113Ala mutation within a factor VIII Ca2+-binding site enhances cofactor interactions in factor Xase.
Biochemistry 2005;44(30):10298-304.
2004: Frank A Baglia; Corie N Shrimpton; Jonas Emsley; Kouki Kitagawa; Zaverio M Ruggeri; José A López; Peter N Walsh
Factor XI interacts with the leucine-rich repeats of glycoprotein Ibalpha on the activated platelet.
The Journal of biological chemistry 2004;279(47):49323-9.
2004: Xia Yang; Yu-Jia Chang; Shu-Wha Lin; Peter N Walsh
Identification of residues Asn89, Ile90, and Val107 of the factor IXa second epidermal growth factor domain that are essential for the assembly of the factor X-activating complex on activated platelets.
The Journal of biological chemistry 2004;279(45):46400-5.
2004: Frank A Baglia; David Gailani; José A López; Peter N Walsh
Identification of a binding site for glycoprotein Ibalpha in the Apple 3 domain of factor XI.
The Journal of biological chemistry 2004;279(44):45470-6.
2004: David Gailani; Ariella Zivelin; D Sinha; Peter N Walsh
Do platelets synthesize factor XI?
Journal of thrombosis and haemostasis : JTH 2004;2(10):1709-12.
2004: Peter N Walsh
Platelet coagulation-protein interactions.
Seminars in thrombosis and hemostasis 2004;30(4):461-71.
2004: Dipali Sinha; Karen O Badellino; Mariola Marcinkiewicz; Peter N Walsh
Allosteric modification of factor XIa functional activity upon binding to polyanions.
Biochemistry 2004;43(23):7593-600.
2004: Fredda S London; Mariola Marcinkiewicz; Peter N Walsh
A subpopulation of platelets responds to thrombin- or SFLLRN-stimulation with binding sites for factor IXa.
The Journal of biological chemistry 2004;279(19):19854-9.
2003: Thomas H Yun; Frank A Baglia; Timothy Myles; Duraiswamy Navaneetham; José A López; Peter N Walsh; Lawrence L K Leung
Thrombin activation of factor XI on activated platelets requires the interaction of factor XI and platelet glycoprotein Ib alpha with thrombin anion-binding exosites I and II, respectively.
The Journal of biological chemistry 2003;278(48):48112-9.
2003: Syed S Ahmad; Fredda S London; Peter N Walsh
Binding studies of the enzyme (factor IXa) with the cofactor (factor VIIIa) in the assembly of factor-X activating complex on the activated platelet surface.
Journal of thrombosis and haemostasis : JTH 2003;1(11):2348-55.
2003: Peter N Walsh
Roles of factor XI, platelets and tissue factor-initiated blood coagulation.
Journal of thrombosis and haemostasis : JTH 2003;1(10):2081-6.
2003: Frank A Baglia; Corie N Shrimpton; José A López; Peter N Walsh
The glycoprotein Ib-IX-V complex mediates localization of factor XI to lipid rafts on the platelet membrane.
The Journal of biological chemistry 2003;278(24):21744-50.
2003: T Regan Baird; Peter N Walsh
Factor XI, but not prekallikrein, blocks high molecular weight kininogen binding to human umbilical vein endothelial cells.
The Journal of biological chemistry 2003;278(23):20618-23.
2003: Syed S Ahmad; Fredda S London; Peter N Walsh
The assembly of the factor X-activating complex on activated human platelets.
Journal of thrombosis and haemostasis : JTH 2003;1(1):48-59.
2002: T Regan Baird; Peter N Walsh
The interaction of factor XIa with activated platelets but not endothelial cells promotes the activation of factor IX in the consolidation phase of blood coagulation.
The Journal of biological chemistry 2002;277(41):38462-7.
2002: Dipali Sinha; Mariola Marcinkiewicz; David Gailani; Peter N Walsh
Molecular cloning and biochemical characterization of rabbit factor XI.
The Biochemical journal 2002;367(Pt 1):49-56.
2002: Syed S Ahmad; Peter N Walsh
Coordinate binding studies of the substrate (factor X) with the cofactor (factor VIII) in the assembly of the factor X activating complex on the activated platelet surface.
Biochemistry 2002;41(37):11269-76.
2002: T Regan Baird; Peter N Walsh
Activated platelets but not endothelial cells participate in the initiation of the consolidation phase of blood coagulation.
The Journal of biological chemistry 2002;277(32):28498-503.
2002: Frank H Wilkinson; Fredda S London; Peter N Walsh
Residues 88-109 of factor IXa are important for assembly of the factor X activating complex.
The Journal of biological chemistry 2002;277(8):5725-33.
2002: Frank H Wilkinson; Syed S Ahmad; Peter N Walsh
The factor IXa second epidermal growth factor (EGF2) domain mediates platelet binding and assembly of the factor X activating complex.
The Journal of biological chemistry 2002;277(8):5734-41.
2002: Frank A Baglia; Karen O Badellino; Chester Q Li; Jose A Lopez; Peter N Walsh
Factor XI binding to the platelet glycoprotein Ib-IX-V complex promotes factor XI activation by thrombin.
The Journal of biological chemistry 2002;277(3):1662-8.
2002: Peter N Walsh; Syed S Ahmad
Proteases in blood clotting.
Essays in biochemistry 2002;38():95-111.
2001: Peter N Walsh
Roles of platelets and factor XI in the initiation of blood coagulation by thrombin.
Thrombosis and haemostasis 2001;86(1):75-82.
2001: Mao-Fu Sun; Frank A Baglia; D Ho; Danko Martincic; R E Ware; Peter N Walsh; David Gailani
Defective binding of factor XI-N248 to activated human platelets.
Blood 2001;98(1):125-9.
2001: Karen O Badellino; Peter N Walsh
Localization of a heparin binding site in the catalytic domain of factor XIa.
Biochemistry 2001;40(25):7569-80.
2001: David Gailani; D Ho; Mao-Fu Sun; Qiufang Cheng; Peter N Walsh
Model for a factor IX activation complex on blood platelets: dimeric conformation of factor XIa is essential.
Blood 2001;97(10):3117-22.
2001: R Dorfman; Peter N Walsh
Noncovalent interactions of the Apple 4 domain that mediate coagulation factor XI homodimerization.
The Journal of biological chemistry 2001;276(9):6429-38.
2000: Frank A Baglia; Karen O Badellino; DH Ho; VR Dasari; Peter N Walsh
A binding site for the kringle II domain of prothrombin in the apple 1 domain of factor XI.
The Journal of biological chemistry 2000;275(41):31954-62.
2000: R A Shirk; B A Konkle; Peter N Walsh
Nonsense mutation in exon V of the factor XI gene does not abolish platelet factor XI expression.
British journal of haematology 2000;111(1):91-5.
2000: DH Ho; Karen O Badellino; Frank A Baglia; Mao-Fu Sun; M M Zhao; David Gailani; Peter N Walsh
The role of high molecular weight kininogen and prothrombin as cofactors in the binding of factor XI A3 domain to the platelet surface.
The Journal of biological chemistry 2000;275(33):25139-45.
2000: Fredda S London; Peter N Walsh
Zymogen factor IX potentiates factor IXa-catalyzed factor X activation.
Biochemistry 2000;39(32):9850-8.
2000: Frank A Baglia; Peter N Walsh
Thrombin-mediated feedback activation of factor XI on the activated platelet surface is preferred over contact activation by factor XIIa or factor XIa.
The Journal of biological chemistry 2000;275(27):20514-9.
2000: Syed S Ahmad; Joseph Michael Scandura; Peter N Walsh
Structural and functional characterization of platelet receptor-mediated factor VIII binding.
The Journal of biological chemistry 2000;275(17):13071-81.
2000: Karen O Badellino; Peter N Walsh
Protease nexin II interactions with coagulation factor XIa are contained within the Kunitz protease inhibitor domain of protease nexin II and the factor XIa catalytic domain.
Biochemistry 2000;39(16):4769-77.
2000: DH Ho; Frank A Baglia; Peter N Walsh
Factor XI binding to activated platelets is mediated by residues R(250), K(255), F(260), and Q(263) within the apple 3 domain.
Biochemistry 2000;39(2):316-23.
1999: Peter N Walsh
Platelets and factor XI bypass the contact system of blood coagulation.
Thrombosis and haemostasis 1999;82(2):234-42.
1999: M Y Wong; JA Gurr; Peter N Walsh
The second epidermal growth factor-like domain of human factor IXa mediates factor IXa binding to platelets and assembly of the factor X activating complex.
Biochemistry 1999;38(28):8948-60.
1998: Y Zhang; J M Ribeiro; J A Guimarães; Peter N Walsh
Nitrophorin-2: a novel mixed-type reversible specific inhibitor of the intrinsic factor-X activating complex.
Biochemistry 1998;37(30):10681-90.
1998: DH Ho; Karen O Badellino; Frank A Baglia; Peter N Walsh
A binding site for heparin in the apple 3 domain of factor XI.
The Journal of biological chemistry 1998;273(26):16382-90.
1998: T C Hsu; Scott K Shore; T Seshsmma; O Bagasra; Peter N Walsh
Molecular cloning of platelet factor XI, an alternative splicing product of the plasma factor XI gene.
The Journal of biological chemistry 1998;273(22):13787-93.
1998: C J Hu; Frank A Baglia; D C Mills; B A Konkle; Peter N Walsh
Tissue-specific expression of functional platelet factor XI is independent of plasma factor XI expression.
Blood 1998;91(10):3800-7.
1998: Frank A Baglia; Peter N Walsh
Prothrombin is a cofactor for the binding of factor XI to the platelet surface and for platelet-mediated factor XI activation by thrombin.
Biochemistry 1998;37(8):2271-81.
1998: Syed S Ahmad; M Y Wong; R Rawala; Bradford A Jameson; Peter N Walsh
Coagulation factor IX residues G4-Q11 mediate its interaction with a shared factor IX/IXa binding site on activated platelets but not the assembly of the functional factor X activating complex.
Biochemistry 1998;37(6):1671-9.
1997: Y Zhang; Joseph Michael Scandura; William E Van Nostrand; Peter N Walsh
The mechanism by which heparin promotes the inhibition of coagulation factor XIa by protease nexin-2.
The Journal of biological chemistry 1997;272(42):26139-44.
1997: Joseph Michael Scandura; Y Zhang; William E Van Nostrand; Peter N Walsh
Progress curve analysis of the kinetics with which blood coagulation factor XIa is inhibited by protease nexin-2.
Biochemistry 1997;36(2):412-20.
1996: F London; S S Ahmad; Peter N Walsh
Annexin V inhibition of factor IXa-catalyzed factor X activation on human platelets and on negatively-charged phospholipid vesicles.
Biochemistry 1996;35(51):16886-97.
1996: F London; Peter N Walsh
The role of electrostatic interactions in the assembly of the factor X activating complex on both activated platelets and negatively-charged phospholipid vesicles.
Biochemistry 1996;35(37):12146-54.
1996: Joseph Michael Scandura; Peter N Walsh
Factor X bound to the surface of activated human platelets is preferentially activated by platelet-bound factor IXa.
Biochemistry 1996;35(27):8903-13.
1996: Joseph Michael Scandura; S S Ahmad; Peter N Walsh
A binding site expressed on the surface of activated human platelets is shared by factor X and prothrombin.
Biochemistry 1996;35(27):8890-902.
1996: Frank A Baglia; Peter N Walsh
A binding site for thrombin in the apple 1 domain of factor XI.
The Journal of biological chemistry 1996;271(7):3652-8.
1995: S S Ahmad; R Rawala; W F Cheung; Darrel W Stafford; Peter N Walsh
The role of the second growth-factor domain of human factor IXa in binding to platelets and in factor-X activation.
The Biochemical journal 1995;310 ( Pt 2)():427-31.
1995: Frank A Baglia; F S Seaman; Peter N Walsh
The Apple 1 and Apple 4 domains of factor XI act synergistically to promote the surface-mediated activation of factor XI by factor XIIa.
Blood 1995;85(8):2078-83.
1995: Frank A Baglia; B A Jameson; Peter N Walsh
Identification and characterization of a binding site for platelets in the Apple 3 domain of coagulation factor XI.
The Journal of biological chemistry 1995;270(12):6734-40.
1994: F S Seaman; Frank A Baglia; J A Gurr; B A Jameson; Peter N Walsh
Binding of high-molecular-mass kininogen to the Apple 1 domain of factor XI is mediated in part by Val64 and Ile77.
The Biochemical journal 1994;304 ( Pt 3)():715-21.
1994: Syed S Ahmad; Peter N Walsh
Platelet membrane-mediated coagulation protease complex assembly.
Trends in cardiovascular medicine 1994;4(6):271-8.
1994: S S Ahmad; R Rawala-Sheikh; W F Cheung; B A Jameson; Darrel W Stafford; Peter N Walsh
High-affinity, specific factor IXa binding to platelets is mediated in part by residues 3-11.
Biochemistry 1994;33(40):12048-55.
1994: Peter N Walsh
Factor XI deficiency and hemostasis.
American journal of hematology 1994;47(2):73-8.
1993: Peter N Walsh; Frank A Baglia; B A Jameson
Factor XI and platelets: activation and regulation.
Thrombosis and haemostasis 1993;70(1):75-9.
1993: Frank A Baglia; B A Jameson; Peter N Walsh
Identification and characterization of a binding site for factor XIIa in the Apple 4 domain of coagulation factor XI.
The Journal of biological chemistry 1993;268(6):3838-44.
1993: Peter N Walsh; Frank A Baglia; B A Jameson
Factor XI: structure-function relationships utilizing monoclonal antibodies protein modification, computational chemistry, and rational synthetic peptide design.
Methods in enzymology 1993;222():65-96.
1992: Peter N Walsh
Factor XI: a renaissance.
Seminars in hematology 1992;29(3):189-201.
1992: S S Ahmad; R Rawala-Sheikh; W F Cheung; Darrel W Stafford; Peter N Walsh
The role of the first growth factor domain of human factor IXa in binding to platelets and in factor X activation.
The Journal of biological chemistry 1992;267(12):8571-6.
1992: Frank A Baglia; B A Jameson; Peter N Walsh
Fine mapping of the high molecular weight kininogen binding site on blood coagulation factor XI through the use of rationally designed synthetic analogs.
The Journal of biological chemistry 1992;267(6):4247-52.
1992: A L Cronlund; Peter N Walsh
A low molecular weight platelet inhibitor of factor XIa: purification, characterization, and possible role in blood coagulation.
Biochemistry 1992;31(6):1685-94.
1992: R Rawala-Sheikh; S S Ahmad; Dougald M Monroe; Harold R Roberts; Peter N Walsh
Role of gamma-carboxyglutamic acid residues in the binding of factor IXa to platelets and in factor-X activation.
Blood 1992;79(2):398-405.
1992: S S Ahmad; R Rawala-Sheikh; Peter N Walsh
Components and assembly of the factor X activating complex.
Seminars in thrombosis and hemostasis 1992;18(3):311-23.
1992: D Sinha; Peter N Walsh
Binding of coagulation factor XIa to receptor on human platelets.
Methods in enzymology 1992;215():361-9.
1991: Frank A Baglia; B A Jameson; Peter N Walsh
Identification and chemical synthesis of a substrate-binding site for factor IX on coagulation factor XIa.
The Journal of biological chemistry 1991;266(35):24190-7.
1990: S S Ahmad; R Rawala-Sheikh; Dougald M Monroe; Harold R Roberts; Peter N Walsh
Comparative platelet binding and kinetic studies with normal and variant factor IXa molecules.
The Journal of biological chemistry 1990;265(34):20907-11.
1990: R Rawala-Sheikh; S S Ahmad; Barrie Ashby; Peter N Walsh
Kinetics of coagulation factor X activation by platelet-bound factor IXa.
Biochemistry 1990;29(10):2606-11.
1990: Frank A Baglia; B A Jameson; Peter N Walsh
Localization of the high molecular weight kininogen binding site in the heavy chain of human factor XI to amino acids phenylalanine 56 through serine 86.
The Journal of biological chemistry 1990;265(7):4149-54.
1989: S S Ahmad; R Rawala-Sheikh; Peter N Walsh
Platelet receptor occupancy with factor IXa promotes factor X activation.
The Journal of biological chemistry 1989;264(33):20012-6.
1989: S S Ahmad; R Rawala-Sheikh; Barrie Ashby; Peter N Walsh
Platelet receptor-mediated factor X activation by factor IXa. High-affinity factor IXa receptors induced by factor VIII are deficient on platelets in Scott syndrome.
The Journal of clinical investigation 1989;84(3):824-8.
1989: S S Ahmad; R Rawala-Sheikh; A R Thompson; Peter N Walsh
Rapid purification of factor IX, factor X and prothrombin by immunoaffinity and ion exchange chromatography.
Thrombosis research 1989;55(1):121-33.
1989: Frank A Baglia; D Sinha; Peter N Walsh
Functional domains in the heavy-chain region of factor XI: a high molecular weight kininogen-binding site and a substrate-binding site for factor IX.
Blood 1989;74(1):244-51.
1989: S S Ahmad; R Rawala-Sheikh; Peter N Walsh
Comparative interactions of factor IX and factor IXa with human platelets.
The Journal of biological chemistry 1989;264(6):3244-51.
1988: R A De La Cadena; Frank A Baglia; C A Johnson; R E Wenk; R Amernick; Peter N Walsh; Robert W Colman
Naturally occurring human antibodies against two distinct functional domains in the heavy chain of FXI/FXIa.
Blood 1988;72(5):1748-54.
1987: Peter N Walsh; D Sinha; F Kueppers; F S Seaman; K B Blankstein
Regulation of factor XIa activity by platelets and alpha 1-protease inhibitor.
The Journal of clinical investigation 1987;80(6):1578-86.
1987: H Holmsen; Peter N Walsh; K Koike; S Murphy; S Holme; M M Johnson; Carol Dangelmaier; J J Egan; J E Benzel; George P Tuszynski
Familial bleeding disorder associated with deficiencies in platelet signal processing and glycoproteins.
British journal of haematology 1987;67(3):335-44.
1987: D Sinha; F S Seaman; Peter N Walsh
Role of calcium ions and the heavy chain of factor XIa in the activation of human coagulation factor IX.
Biochemistry 1987;26(13):3768-75.
1986: H Akiyama; D Sinha; F S Seaman; E P Kirby; Peter N Walsh
Mechanism of activation of coagulation factor XI by factor XIIa studied with monoclonal antibodies.
The Journal of clinical investigation 1986;78(6):1631-7.
1986: Peter N Walsh; D Sinha; A Koshy; F S Seaman; H Bradford
Functional characterization of platelet-bound factor XIa: retention of factor XIa activity on the platelet surface.
Blood 1986;68(1):225-30.
1985: S Idell; Umberto Kucich; A Fein; F Kueppers; Harold L James; Peter N Walsh; G Weinbaum; Robert W Colman; A B Cohen
Neutrophil elastase-releasing factors in bronchoalveolar lavage from patients with adult respiratory distress syndrome.
The American review of respiratory disease 1985;132(5):1098-105.
1985: D Sinha; A Koshy; F S Seaman; Peter N Walsh
Functional characterization of human blood coagulation factor XIa using hybridoma antibodies.
The Journal of biological chemistry 1985;260(19):10714-9.
1985: M V Ragni; D Sinha; F Seaman; J H Lewis; J A Spero; Peter N Walsh
Comparison of bleeding tendency, factor XI coagulant activity, and factor XI antigen in 25 factor XI-deficient kindreds.
Blood 1985;65(3):719-24.
1984: D Sinha; F S Seaman; A Koshy; L C Knight; Peter N Walsh
Blood coagulation factor XIa binds specifically to a site on activated human platelets distinct from that for factor XI.
The Journal of clinical investigation 1984;73(6):1550-6.
1984: Peter N Walsh; H Bradford; D Sinha; J R Piperno; G P Tuszynski
Kinetics of the Factor XIa catalyzed activation of human blood coagulation Factor IX.
The Journal of clinical investigation 1984;73(5):1392-9.
1984: C F Scott; D Sinha; F S Seaman; Peter N Walsh; R W Colman
Amidolytic assay of human factor XI in plasma: comparison with a coagulant assay and a new rapid radioimmunoassay.
Blood 1984;63(1):42-50.
1982: G P Tuszynski; Peter N Walsh; J R Piperno; A Koshy
Association of coagulation factor V with the platelet cytoskeleton.
The Journal of biological chemistry 1982;257(8):4557-63.