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David Wan

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Xuelin Zhou; Pui Man Hoi; Tao Hu; Yiu Wa Kwan; Paul B S Lai; Penelope M Y Or; David C C Wan; Yan Wang; John Wong; John H K Yeung
Enzyme kinetic and molecular docking studies for the inhibitions of miltirone on major human cytochrome P450 isozymes.
Xuelin Zhou; Yiu Wa Kwan; Penelope M Y Or; David C C Wan; Yan Wang; John H K Yeung
Molecular docking and enzyme kinetic studies of dihydrotanshinone on metabolism of a model CYP2D6 probe substrate in human liver microsomes.
Jack Ho Wong; Anna Legowska; Krzysztof Rolka; Tzi Bun Ng; Mamie Hui; Chi-Hin Cho; Wendy Wai Ling Lam; Shannon Wing Ngor Au; Oscar Wangang Gu; David C C Wan
Effects of cathelicidin and its fragments on three key enzymes of HIV-1.

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All Publications

2013: Xuelin Zhou; Pui Man Hoi; Tao Hu; Yiu Wa Kwan; Paul B S Lai; Penelope M Y Or; David C C Wan; Yan Wang; John Wong; John H K Yeung
Enzyme kinetic and molecular docking studies for the inhibitions of miltirone on major human cytochrome P450 isozymes.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2013;20(3-4):367-74.
2012: Xuelin Zhou; Yiu Wa Kwan; Penelope M Y Or; David C C Wan; Yan Wang; John H K Yeung
Molecular docking and enzyme kinetic studies of dihydrotanshinone on metabolism of a model CYP2D6 probe substrate in human liver microsomes.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2012;19(7):648-57.
2011: Jack Ho Wong; Anna Legowska; Krzysztof Rolka; Tzi Bun Ng; Mamie Hui; Chi-Hin Cho; Wendy Wai Ling Lam; Shannon Wing Ngor Au; Oscar Wangang Gu; David C C Wan
Effects of cathelicidin and its fragments on three key enzymes of HIV-1.
Peptides 2011;32(6):1117-22.
2010: Shuo Li; Denis Tsz-Ming Ip; Hai-Qing Lin; Jian Mei Liu; Yun-gen Miao; Li Jian Ke; David C C Wan
High-level expression of functional recombinant human butyrylcholinesterase in silkworm larvae by Bac-to-Bac system.
Chemico-biological interactions 2010;187(1-3):101-5.
2010: Hai-Qing Lin; Roy C Y Choi; Kam-Leung Chan; Denis Tsz-Ming Ip; Karl W K Tsim; David C C Wan
Differential gene expression profiling on the muscle of acetylcholinesterase knockout mice: a preliminary analysis.
Chemico-biological interactions 2010;187(1-3):120-3.
2010: Kelvin Kin-Kwan Wong; Jacky Chi Ki Ngo; Sijie Liu; Hai-Qing Lin; Chun Hu; Pang-Chui Shaw; David C C Wan
Interaction study of two diterpenes, cryptotanshinone and dihydrotanshinone, to human acetylcholinesterase and butyrylcholinesterase by molecular docking and kinetic analysis.
Chemico-biological interactions 2010;187(1-3):335-9.
2008: Hai-Qing Lin; Michelle Tsz Wan Ho; Lesley S Lau; Kelvin K Wong; Pang-Chui Shaw; David C C Wan
Anti-acetylcholinesterase activities of traditional Chinese medicine for treating Alzheimer's disease.
Chemico-biological interactions 2008;175(1-3):352-4.
2007: Tat San Lau; Yonggang Li; Masanori Kameoka; Tzi Bun Ng; David C C Wan
Suppression of HIV replication using RNA interference against HIV-1 integrase.
FEBS letters 2007;581(17):3253-9.
2007: Denis Tsz-Ming Ip; Kam-Bo Wong; David C C Wan
Characterization of novel orange fluorescent protein cloned from cnidarian tube anemone Cerianthus sp.
Marine biotechnology (New York, N.Y.) 2007;9(4):469-78.
2006: David C C Wan; Xiang Zhang; Nina L Siow; Heidi Q Xie; Karl W K Tsim
Chick acetylcholinesterase promoter regulation.
Journal of molecular neuroscience : MN 2006;30(1-2):33-4.
2004: Susanna S T Lee; Wood Yee Chan; Cherry K C Lo; David C C Wan; David S C Tsang; Wing-Tai Cheung
Requirement of PPARalpha in maintaining phospholipid and triacylglycerol homeostasis during energy deprivation.
Journal of lipid research 2004;45(11):2025-37.
2004: Denis Tsz-Ming Ip; Siu-Hong Chan; Mark D Allen; Mark Bycroft; David C C Wan; Kam-Bo Wong
Crystallization and preliminary crystallographic analysis of a novel orange fluorescent protein from the Cnidaria tube anemone Cerianthus sp.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 2):340-1.
2003: Joy X S Jiang; Roy C Y Choi; Nina L Siow; Henry H C Lee; David C C Wan; Karl W K Tsim
Muscle induces neuronal expression of acetylcholinesterase in neuron-muscle co-culture: transcriptional regulation mediated by cAMP-dependent signaling.
The Journal of biological chemistry 2003;278(46):45435-44.
2002: Nina L Siow; Roy C Y Choi; Anthony W M Cheng; Joy X S Jiang; David C C Wan; Shang Q Zhu; Karl W K Tsim
A cyclic AMP-dependent pathway regulates the expression of acetylcholinesterase during myogenic differentiation of C2C12 cells.
The Journal of biological chemistry 2002;277(39):36129-36.
2002: Hong-Bing Yao; Pang-Chui Shaw; Chun-Cheung Wong; David C C Wan
Expression of glycogen synthase kinase-3 isoforms in mouse tissues and their transcription in the brain.
Journal of chemical neuroanatomy 2002;23(4):291-7.
2002: Tzi Bun Ng; TK Au; TL Lam; XY Ye; David C C Wan
Inhibitory effects of antifungal proteins on human immunodeficiency virus type 1 reverse transcriptase, protease and integrase.
Life sciences 2002;70(8):927-35.
2001: Roy C Y Choi; Nina L Siow; Shang Q Zhu; David C C Wan; Y H Wong; Karl W K Tsim
The cyclic AMP-mediated expression of acetylcholinesterase in myotubes shows contrasting activation and repression between avian and mammalian enzymes.
Molecular and cellular neurosciences 2001;17(4):732-45.
2001: TK Au; TL Lam; Tzi Bun Ng; Wing-Ping Fong; David C C Wan
A comparison of HIV-1 integrase inhibition by aqueous and methanol extracts of Chinese medicinal herbs.
Life sciences 2001;68(14):1687-94.
2000: TL Lam; M L Lam; TK Au; Denis Tsz-Ming Ip; Tzi Bun Ng; Wing-Ping Fong; David C C Wan
A comparison of human immunodeficiency virus type-1 protease inhibition activities by the aqueous and methanol extracts of Chinese medicinal herbs.
Life sciences 2000;67(23):2889-96.
2000: David C C Wan; Roy C Y Choi; Nina L Siow; Karl W K Tsim
The promoter of human acetylcholinesterase is activated by a cyclic adenosine 3',5'-monophosphate-dependent pathway in cultured NG108-15 neuroblastoma cells.
Neuroscience letters 2000;288(1):81-5.
2000: TK Au; Richard Collins; TL Lam; Tzi Bun Ng; Wing-Ping Fong; David C C Wan
The plant ribosome inactivating proteins luffin and saporin are potent inhibitors of HIV-1 integrase.
FEBS letters 2000;471(2-3):169-72.
1999: David C C Wan; L K Law; Denis Tsz-Ming Ip; Wing-Tai Cheung; Walter K K Ho; Karl W K Tsim; R Kay; J Woo; C P Pang
Lack of allelic association of dopamine D4 receptor gene polymorphisms with Parkinson's disease in a Chinese population.
Movement disorders : official journal of the Movement Disorder Society 1999;14(2):225-9.
1999: Wing-Tai Cheung; S Y Yeung; A K Yiu; T M Ip; David C C Wan; SK Luk; W K Ho
Characterization of a functional AT1A angiotensin receptor in pancreatoma AR4-2J cells.
Peptides 1999;20(7):829-36.
1998: Roy C Y Choi; Lisa Y Yung; Tina T X Dong; David C C Wan; Yung H Wong; Karl W K Tsim
The calcitonin gene-related peptide-induced acetylcholinesterase synthesis in cultured chick myotubes is mediated by cyclic AMP.
Journal of neurochemistry 1998;71(1):152-60.
1998: Roy C Y Choi; S C Yam; B Hui; David C C Wan; Karl W K Tsim
Over-expression of acetylcholinesterase stimulates the expression of agrin in NG108-15 cells.
Neuroscience letters 1998;248(1):17-20.
1997: Roy C Y Choi; San Pun; Tina T X Dong; David C C Wan; Karl W K Tsim
NG108-15 cells induce the expression of muscular acetylcholinesterase when co-cultured with myotubes.
Neuroscience letters 1997;236(3):167-70.
1997: David C C Wan; Yu Pong Ng; Roy C Y Choi; P W Cheung; Tina T X Dong; Karl W K Tsim
Denervation decreases the ipsilateral expression of AChE in chick lumbaric motor neurons.
Neuroscience letters 1997;232(2):83-6.
1997: Karl W K Tsim; Roy C Y Choi; Tina T X Dong; David C C Wan
A globular, not asymmetric, form of acetylcholinesterase is expressed in chick motor neurons: down-regulation toward maturity and after denervation.
Journal of neurochemistry 1997;68(2):479-87.
1997: David C C Wan; SK Luk; Karl W K Tsim; Wing-Tai Cheung
Expression and localization of endothelin converting enzyme in rat vas deferens.
Life sciences 1997;60(18):1605-12.
1996: Roy C Y Choi; P W Leung; Tina T X Dong; David C C Wan; Karl W K Tsim
Calcitonin gene-related peptide increases the expression of acetylcholinesterase in cultured chick myotubes.
Neuroscience letters 1996;217(2-3):165-8.
1996: C S Sum; David C C Wan; Wing-Tai Cheung
Potentiation of purinergic transmission by angiotensin in prostatic rat vas deferens.
British journal of pharmacology 1996;118(6):1523-9.
1996: K L So; San Pun; David C C Wan; Karl W K Tsim
Cerebellar granule cells express a specific isoform of agrin that lacks the acetylcholine receptor aggregating activity.
FEBS letters 1996;379(1):63-8.