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Andrew H-J Wang

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Hao-Ching Wang; Mao-Lun Wu; Tzu-Ping Ko; Andrew H-J Wang
Neisseria conserved hypothetical protein DMP12 is a DNA mimic that binds to histone-like HU protein.
Min-Feng Hsu; Chia-Cheng Chou; Hsu-Yuan Fu; Chii-Shen Yang; Tsung-Fu Yu; Andrew H-J Wang
Using Haloarcula marismortui bacteriorhodopsin as a fusion tag for enhancing and visible expression of integral membrane proteins in Escherichia coli.
Cyong-Yi Wang; Shan Chi Ku; Cheng-Chung Lee; Andrew H-J Wang
Modulating the function of human serine racemase and human serine dehydratase by protein engineering.

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All Publications

2013: Hao-Ching Wang; Mao-Lun Wu; Tzu-Ping Ko; Andrew H-J Wang
Neisseria conserved hypothetical protein DMP12 is a DNA mimic that binds to histone-like HU protein.
Nucleic acids research 2013;41(9):5127-38.
2013: Min-Feng Hsu; Chia-Cheng Chou; Hsu-Yuan Fu; Chii-Shen Yang; Tsung-Fu Yu; Andrew H-J Wang
Using Haloarcula marismortui bacteriorhodopsin as a fusion tag for enhancing and visible expression of integral membrane proteins in Escherichia coli.
PloS one 2013;8(2):e56363.
2012: Cyong-Yi Wang; Shan Chi Ku; Cheng-Chung Lee; Andrew H-J Wang
Modulating the function of human serine racemase and human serine dehydratase by protein engineering.
Protein engineering, design & selection : PEDS 2012;25(11):741-9.
2012: Wei-Chun Liu; Je-Hsin Chen; Wen-Yih Jeng; Yu-Shiun Lin; Andrew H-J Wang; Lie-Fen Shyur
Engineering of dual-functional hybrid glucanases.
Protein engineering, design & selection : PEDS 2012;25(11):771-80.
2012: Sheng-Chung Chen; Chih-An Hsu; Yu-Chang Su; Andrew H-J Wang; Nai-Chen Wang; Yun-Syuan Wei; Tuan-Nan Wen; Po-Hung Wu; Lie-Fen Shyur
Biochemical characterization of a novel laccase from the basidiomycete fungus Cerrena sp. WR1.
Protein engineering, design & selection : PEDS 2012;25(11):761-9.
2012: Hsiao-Lin Lee; Chih-Kang Chang; Wen-Yih Jeng; Andrew H-J Wang; Po-Huang Liang
Mutations in the substrate entrance region of β-glucosidase from Trichoderma reesei improve enzyme activity and thermostability.
Protein engineering, design & selection : PEDS 2012;25(11):733-40.
2012: Ya-Shan Cheng; Chun-Hsiang Huang; Jian-Wen Huang; Tzu-Ping Ko; Qian Li; Cheng-Yen Lin; Je-Ruei Liu; Wenhua Luo; Yanhe Ma; Andrew H-J Wang; Tzu-Hui Wu; Rey-Ting Guo
Enhanced activity of Thermotoga maritima cellulase 12A by mutating a unique surface loop.
Applied microbiology and biotechnology 2012;95(3):661-9.
2012: Wen-Yih Jeng; Cheng-Tse Lin; Chia-I Liu; Wei-Jung Chang; Nai-Chen Wang; Andrew H-J Wang
High-resolution structures of Neotermes koshunensis β-glucosidase mutants provide insights into the catalytic mechanism and the synthesis of glucoconjugates.
Acta crystallographica. Section D, Biological crystallography 2012;68(Pt 7):829-38.
2012: Chia-Chi Flora Huang; Chin-Chun Hung; Dongyan Qin; John Y-J Shyy; Andrew H-J Wang; Shun-Chang Wang; Tong-You Wade Wei; Jui-Hung Weng; Pei-Yu Gabriel Wu; Shui-Tsung Chen; Yu-Hou Chen; Pang-Hung Hsu; Ming-Daw Tsai
Intermolecular binding between TIFA-FHA and TIFA-pT mediates tumor necrosis factor alpha stimulation and NF-κB activation.
Molecular and cellular biology 2012;32(14):2664-73.
2012: Hao-Ching Wang; Hsing-Ju Wu; Mao-Lun Wu; Tzu-Ping Ko; Shan-Chi Ku; Andrew H-J Wang
Neisseria conserved protein DMP19 is a DNA mimic protein that prevents DNA binding to a hypothetical nitrogen-response transcription factor.
Nucleic acids research 2012;40(12):5718-30.
2012: Shiuan-Woei LinWu; Fu-Chuo Peng; Che-An Wu; Andrew H-J Wang
Structure-based development of bacterial nitroreductase against nitrobenzodiazepine-induced hypnosis.
Biochemical pharmacology 2012;83(12):1690-9.
2012: Chia-I Liu; Wei-Jung Chang; Wen-Yih Jeng; Tzu-Ping Ko; Andrew H-J Wang
Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase.
The Journal of biological chemistry 2012;287(22):18750-7.
2012: Feifei Ren; Andrew H-J Wang; Ke Wang; Hsiu-Chien Chan; Xinxin Feng; Yumei Hu; Chun-Hsiang Huang; Tzu-Ping Ko; Po-Huang Liang; Yanhe Ma; Eric Oldfield; Rey-Ting Guo
Insights into the mechanism of the antibiotic-synthesizing enzyme MoeO5 from crystal structures of different complexes.
Angewandte Chemie (International ed. in English) 2012;51(17):4157-60.
2012: Yi-Ling Chen; Kai-Fa Huang; Wen-Chih Kuo; Yu-May Lee; Yan-Chung Lo; Andrew H-J Wang
Inhibition of glutaminyl cyclase attenuates cell migration modulated by monocyte chemoattractant proteins.
The Biochemical journal 2012;442(2):403-12.
2012: Chih-Hui Yang; Chen-Sheng Yeh; Keng-Shiang Huang; Andrew H-J Wang; Chih-Yu Wang; Wei-Ting Wang; Ming-Yu Lin
Facile synthesis of radial-like macroporous superparamagnetic chitosan spheres with in-situ co-precipitation and gelation of ferro-gels.
PloS one 2012;7(11):e49329.
2012: Yu-Ming Chang; Cammy K-M Chen; Ming-Hon Hou; Wen-Yih Jeng; Yuan-Chih Chang; Andrew H-J Wang
Functional studies of ssDNA binding ability of MarR family protein TcaR from Staphylococcus epidermidis.
PloS one 2012;7(9):e45665.
2011: Chao-Yu Yang; Ko-Hsin Chin; Mary Lay-Cheng Chuah; Zhao-Xun Liang; Andrew H-J Wang; Shan-Ho Chou
The structure and inhibition of a GGDEF diguanylate cyclase complexed with (c-di-GMP)(2) at the active site.
Acta crystallographica. Section D, Biological crystallography 2011;67(Pt 12):997-1008.
2011: Chih Wen Tseng; Andrew H-J Wang; Hao Ching Wang; Ya Shan Cheng; Rey-Ting Guo; Chun Hsiang Huang; Jian Wen Huang; Tzu-Ping Ko; Je-Ruei Liu
Substrate binding of a GH5 endoglucanase from the ruminal fungus Piromyces rhizinflata.
Acta crystallographica. Section F, Structural biology and crystallization communications 2011;67(Pt 10):1189-94.
2011: Cammy K-M Chen; Nei-Li Chan; Andrew H-J Wang
The many blades of the β-propeller proteins: conserved but versatile.
Trends in biochemical sciences 2011;36(10):553-61.
2011: Ying-Yin Chen; Tzu-Ping Ko; Chun-Hung Lin; Wei-Hung Chen; Andrew H-J Wang
Conformational change upon product binding to Klebsiella pneumoniae UDP-glucose dehydrogenase: a possible inhibition mechanism for the key enzyme in polymyxin resistance.
Journal of structural biology 2011;175(3):300-10.
2011: Chun-Hua Hsu; Andrew H-J Wang
The DNA-recognition fold of Sso7c4 suggests a new member of SpoVT-AbrB superfamily from archaea.
Nucleic acids research 2011;39(15):6764-74.
2011: Tzu-Huei Kao; Yeh Chen; Chien-Hua Pai; Ming-Chung Chang; Andrew H-J Wang
Structure of a NADPH-dependent blue fluorescent protein revealed the unique role of Gly176 on the fluorescence enhancement.
Journal of structural biology 2011;174(3):485-93.
2011: Chien-Yu Chou; Tzu-Ping Ko; Kuan-Jung Wu; Kai-Fa Huang; Chun-Hung Lin; Chi-Huey Wong; Andrew H-J Wang
Modulation of substrate specificities of D-sialic acid aldolase through single mutations of Val-251.
The Journal of biological chemistry 2011;286(16):14057-64.
2011: Kai-Fa Huang; Su-Sen Liaw; Wei-Lin Huang; Cho-Yun Chia; Yan-Chung Lo; Yi-Ling Chen; Andrew H-J Wang
Structures of human Golgi-resident glutaminyl cyclase and its complexes with inhibitors reveal a large loop movement upon inhibitor binding.
The Journal of biological chemistry 2011;286(14):12439-49.
2011: Ya-Shan Cheng; Tzu-Ping Ko; Tzu-Hui Wu; Yanhe Ma; Chun-Hsiang Huang; Hui-Lin Lai; Andrew H-J Wang; Je-Ruei Liu; Rey-Ting Guo
Crystal structure and substrate-binding mode of cellulase 12A from Thermotoga maritima.
Proteins 2011;79(4):1193-204.
2011: Chien-Hua Pai; Hsing-Ju Wu; Chun-Hung Lin; Andrew H-J Wang
Structure and mechanism of Escherichia coli glutathionylspermidine amidase belonging to the family of cysteine; histidine-dependent amidohydrolases/peptidases.
Protein science : a publication of the Protein Society 2011;20(3):557-66.
2011: Fu-Lien Hsieh; Tao-Hsin Chang; Tzu-Ping Ko; Andrew H-J Wang
Structure and mechanism of an Arabidopsis medium/long-chain-length prenyl pyrophosphate synthase.
Plant physiology 2011;155(3):1079-90.
2011: Tso-Ning Li; Andrew H-J Wang; Ming-Te Yang; Ko-Hsin Chin; Kit-Man Fung; Shan-Ho Chou
A novel tetrameric PilZ domain structure from xanthomonads.
PloS one 2011;6(7):e22036.
2011: Cheng-Chung Lee; Ta-Wei Lin; Tzu-Ping Ko; Andrew H-J Wang
The hexameric structures of human heat shock protein 90.
PloS one 2011;6(5):e19961.
2011: Wen-Yih Jeng; Nai-Chen Wang; Man-Hua Lin; Cheng-Tse Lin; Yen-Chywan Liaw; Wei-Jung Chang; Chia-I Liu; Po-Huang Liang; Andrew H-J Wang
Structural and functional analysis of three β-glucosidases from bacterium Clostridium cellulovorans, fungus Trichoderma reesei and termite Neotermes koshunensis.
Journal of structural biology 2011;173(1):46-56.
2010: Fu-Lien Hsieh; Tao-Hsin Chang; Tzu-Ping Ko; Andrew H-J Wang
Enhanced specificity of mint geranyl pyrophosphate synthase by modifying the R-loop interactions.
Journal of molecular biology 2010;404(5):859-73.
2010: Fu-Yang Lin; Chia-I Liu; Yi-Liang Liu; Yonghui Zhang; Ke Wang; Wen-Yih Jeng; Tzu-Ping Ko; Rong Cao; Andrew H-J Wang; Eric Oldfield
Mechanism of action and inhibition of dehydrosqualene synthase.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(50):21337-42.
2010: Hsin-Liang Chen; Jack C-C Hsu; Man Hoang Viet; Mai Suan Li; Chin-Kun Hu; Chia-Hsun Liu; Frederick Y Luh; Silvia S-W Chen; Evan S-H Chang; Andrew H-J Wang; Min-Feng Hsu; Wunshain Fann; Rita P-Y Chen
Studying submicrosecond protein folding kinetics using a photolabile caging strategy and time-resolved photoacoustic calorimetry.
Proteins 2010;78(14):2973-83.
2010: Shih-Huang Chang; Jeng-Liang Han; Susan Y Tseng; Hsin-Yu Lee; Chin-Wei Lin; Yu-Chen Lin; Wen-Yih Jeng; Andrew H-J Wang; Chung-Yi Wu; Chi-Huey Wong
Glycan array on aluminum oxide-coated glass slides through phosphonate chemistry.
Journal of the American Chemical Society 2010;132(38):13371-80.
2010: Hsing-Mao Chu; Feng-Yuan Chen; Tzu-Ping Ko; Andrew H-J Wang
Binding and catalysis of Humulus lupulus adenylate isopentenyltransferase for the synthesis of isopentenylated diadenosine polyphosphates.
FEBS letters 2010;584(18):4083-8.
2010: Kuei-Min Chung; Jai-Hong Cheng; Ching-Shu Suen; Chih-Hsiang Huang; Cheng-Han Tsai; Li-Hao Huang; Yi-Rong Chen; Andrew H-J Wang; Weir-Torn Jiaang; Ming-Jing Hwang; Xin Chen
The dimeric transmembrane domain of prolyl dipeptidase DPP-IV contributes to its quaternary structure and enzymatic activities.
Protein science : a publication of the Protein Society 2010;19(9):1627-38.
2010: Wei-Lin Huang; Yu-Ruei Wang; Tzu-Ping Ko; Cho-Yun Chia; Kai-Fa Huang; Andrew H-J Wang
Crystal structure and functional analysis of the glutaminyl cyclase from Xanthomonas campestris.
Journal of molecular biology 2010;401(3):374-88.
2010: Bing-Yu Chiang; Tzu-Chieh Chen; Chien-Hua Pai; Chi-Chi Chou; Hsuan-He Chen; Tzu-Ping Ko; Wen-Hung Hsu; Chun-Yang Chang; Whei-Fen Wu; Andrew H-J Wang; Chun-Hung Lin
Protein S-thiolation by Glutathionylspermidine (Gsp): the role of Escherichia coli Gsp synthetASE/amidase in redox regulation.
The Journal of biological chemistry 2010;285(33):25345-53.
2010: Shiuan-Woei LinWu; Andrew H-J Wang; Fu-Chuo Peng
Flavin-containing reductase: new perspective on the detoxification of nitrobenzodiazepine.
Expert opinion on drug metabolism & toxicology 2010;6(8):967-81.
2010: Li-Tzu Chen; Andrew H-J Wang
A rationally designed peptide enhances homologous recombination in vitro and resistance to DNA damaging agents in vivo.
Nucleic acids research 2010;38(13):4361-71.
2010: Yi Che Su; Ko-Hsin Chin; Hui Chih Hung; Gwan-Han Shen; Andrew H-J Wang; Shan-Ho Chou
Structure of Stenotrophomonas maltophilia FeoA complexed with zinc: a unique prokaryotic SH3-domain protein that possibly acts as a bacterial ferrous iron-transport activating factor.
Acta crystallographica. Section F, Structural biology and crystallization communications 2010;66(Pt 6):636-42.
2010: Yu-Ming Chang; Wen-Yih Jeng; Tzu-Ping Ko; Yao-Jen Yeh; Cammy K-M Chen; Andrew H-J Wang
Structural study of TcaR and its complexes with multiple antibiotics from Staphylococcus epidermidis.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(19):8617-22.
2010: Hsing-Ju Wu; Kate L Seib; Yogitha N Srikhanta; Jennifer Edwards; Stephen P Kidd; Tina L Maguire; Amanda Hamilton; Kuan-Tin Pan; He-Hsuan Hsiao; Chen-Wen Yao; Sean M Grimmond; Michael A Apicella; Alastair G McEwan; Andrew H-J Wang; Michael P Jennings
Manganese regulation of virulence factors and oxidative stress resistance in Neisseria gonorrhoeae.
Journal of proteomics 2010;73(5):899-916.
2010: Hsing-Mao Chu; Tzu-Ping Ko; Andrew H-J Wang
Crystal structure and substrate specificity of plant adenylate isopentenyltransferase from Humulus lupulus: distinctive binding affinity for purine and pyrimidine nucleotides.
Nucleic acids research 2010;38(5):1738-48.
2010: Ko-Hsin Chin; Yen-Chung Lee; Zhi-Le Tu; Chih-Hua Chen; Yi-Hsiung Tseng; Jinn-Moon Yang; Robert P Ryan; Yvonne McCarthy; J Maxwell Dow; Andrew H-J Wang; Shan-Ho Chou
The cAMP receptor-like protein CLP is a novel c-di-GMP receptor linking cell-cell signaling to virulence gene expression in Xanthomonas campestris.
Journal of molecular biology 2010;396(3):646-62.
2010: Tao-Hsin Chang; Fu-Lien Hsieh; Tzu-Ping Ko; Kuo-Hsun Teng; Po-Huang Liang; Andrew H-J Wang
Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation.
The Plant cell 2010;22(2):454-67.
2010: Tzu-Ping Ko; Wen-Yih Jeng; Chia-I Liu; Ming-Derg Lai; Chun-Lan Wu; Wei-Jung Chang; Hui-Lin Shr; Te-Jung Lu; Andrew H-J Wang
Structures of human MST3 kinase in complex with adenine, ADP and Mn2+.
Acta crystallographica. Section D, Biological crystallography 2010;66(Pt 2):145-54.
2010: Yun-Shiang Chang; Wang-Jing Liu; Cheng-Chung Lee; Tsung-Lu Chou; Yuan-Ting Lee; Tz-Shian Wu; Jiun-Yan Huang; Wei-Tung Huang; Tai-Lin Lee; Guang-Hsiung Kou; Andrew H-J Wang; Chu-Fang Lo
A 3D model of the membrane protein complex formed by the white spot syndrome virus structural proteins.
PloS one 2010;5(5):e10718.
2010: Hsing-Ju Wu; Ching-Wen Ho; Tzu-Ping Ko; Shinde D Popat; Chun-Hung Lin; Andrew H-J Wang
Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range.
Angewandte Chemie (International ed. in English) 2010;49(2):337-40.
2010: Ying-Yin Chen; Tzu-Ping Ko; Wei-Hung Chen; Li-Ping Lo; Chun-Hung Lin; Andrew H-J Wang
Conformational changes associated with cofactor/substrate binding of 6-phosphogluconate dehydrogenase from Escherichia coli and Klebsiella pneumoniae: Implications for enzyme mechanism.
Journal of structural biology 2010;169(1):25-35.
2009: Tso Ning Li; Ko-Hsin Chin; Hui Ling Shih; Andrew H-J Wang; Shan-Ho Chou
Crystallization and preliminary X-ray diffraction characterization of an essential protein from Xanthomonas campestris that contains a noncanonical PilZ signature motif yet is critical for pathogenicity.
Acta crystallographica. Section F, Structural biology and crystallization communications 2009;65(Pt 10):1056-9.
2009: Xian Ya Lin; Shu Ju Liao; Ko-Hsin Chin; Hui Ling Shih; Gwan-Han Shen; Andrew H-J Wang; Shan-Ho Chou
Crystallization and preliminary X-ray diffraction characterization of RpfF, a key DSF synthase from Stenotrophomonas maltophilia.
Acta crystallographica. Section F, Structural biology and crystallization communications 2009;65(Pt 10):1021-3.
2009: Tung-Yi Tsai; Chao-Yu Yang; Hui-Ling Shih; Andrew H-J Wang; Shan-Ho Chou
Xanthomonas campestris PqqD in the pyrroloquinoline quinone biosynthesis operon adopts a novel saddle-like fold that possibly serves as a PQQ carrier.
Proteins 2009;76(4):1042-8.
2009: Shu-Ju Liao; Chao-Yu Yang; Ko-Hsin Chin; Andrew H-J Wang; Shan-Ho Chou
Insights into the alkyl peroxide reduction pathway of Xanthomonas campestris bacterioferritin comigratory protein from the trapped intermediate-ligand complex structures.
Journal of molecular biology 2009;390(5):951-66.
2009: Cammy K-M Chen; Guan-Chiun Lee; Tzu-Ping Ko; Rey-Ting Guo; Li-Min Huang; Hsiao-Jung Liu; Yi-Fang Ho; Jei-Fu Shaw; Andrew H-J Wang
Structure of the alkalohyperthermophilic Archaeoglobus fulgidus lipase contains a unique C-terminal domain essential for long-chain substrate binding.
Journal of molecular biology 2009;390(4):672-85.
2009: Yongcheng Song; Chia-I Liu; Fu-Yang Lin; Joo Hwan No; Mary Hensler; Yi-Liang Liu; Wen-Yih Jeng; Jennifer Low; George Y Liu; Victor Nizet; Andrew H-J Wang; Eric Oldfield
Inhibition of staphyloxanthin virulence factor biosynthesis in Staphylococcus aureus: in vitro, in vivo, and crystallographic results.
Journal of medicinal chemistry 2009;52(13):3869-80.
2009: Yan-Chung Lo; Tzu-Ping Ko; Wen-Chi Su; Tsann-Long Su; Andrew H-J Wang
Terpyridine-platinum(II) complexes are effective inhibitors of mammalian topoisomerases and human thioredoxin reductase 1.
Journal of inorganic biochemistry 2009;103(7):1082-92.
2009: Shiuan-Woei Linwu; Cheng-Jie Syu; Yu-Lian Chen; Andrew H-J Wang; Fu-Chuo Peng
Characterization of Escherichia coli nitroreductase NfsB in the metabolism of nitrobenzodiazepines.
Biochemical pharmacology 2009;78(1):96-103.
2009: Hao-Hsien Lee; Yih-Huei Uen; Yu-Feng Tian; Chi-Shu Sun; Ming-Jen Sheu; Hsing-Tao Kuo; Lok-Beng Koay; Ching-Yih Lin; Ching-Cherng Tzeng; Chia-Ju Cheng; Ling-Yu Tang; Sun-Lung Tsai; Andrew H-J Wang
Wnt-1 protein as a prognostic biomarker for hepatitis B-related and hepatitis C-related hepatocellular carcinoma after surgery.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(5):1562-9.
2009: Tso-Ning Li; Ko-Hsin Chin; Jyung-Hurng Liu; Andrew H-J Wang; Shan-Ho Chou
XC1028 from Xanthomonas campestris adopts a PilZ domain-like structure without a c-di-GMP switch.
Proteins 2009;75(2):282-8.
2009: Hui-Ju Chen; Tzu-Ping Ko; Chia-Yin Lee; Nai-Chen Wang; Andrew H-J Wang
Structure, assembly, and mechanism of a PLP-dependent dodecameric L-aspartate beta-decarboxylase.
Structure (London, England : 1993) 2009;17(4):517-29.
2009: Yonghui Zhang; Rong Cao; Fenglin Yin; Michael P Hudock; Rey-Ting Guo; Kilannin Krysiak; Sujoy Mukherjee; Yi-Gui Gao; Howard Robinson; Yongcheng Song; Joo Hwan No; Kyle Bergan; Annette Leon; Lauren Cass; Amanda Goddard; Ting-Kai Chang; Fu-Yang Lin; Ermond van Beek; Socrates Papapoulos; Andrew H-J Wang; Tadahiko Kubo; Mitsuo Ochi; Dushyant Mukkamala; Eric Oldfield
Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation.
Journal of the American Chemical Society 2009;131(14):5153-62.
2009: Yogitha N Srikhanta; Stefanie J Dowideit; Jennifer L Edwards; Megan L Falsetta; Hsing-Ju Wu; Odile B Harrison; Kate L Fox; Kate L Seib; Tina L Maguire; Andrew H-J Wang; Martin C Maiden; Sean M Grimmond; Michael A Apicella; Michael P Jennings
Phasevarions mediate random switching of gene expression in pathogenic Neisseria.
PLoS pathogens 2009;5(4):e1000400.
2009: Cheng-Chung Lee; Chih-Jung Kuo; Tzu-Ping Ko; Min-Feng Hsu; Yao-Chen Tsui; Shih-Cheng Chang; Syaulan Yang; Shu-Jen Chen; Hua-Chien Chen; Ming-Chu Hsu; Shin-Ru Shih; Po-Huang Liang; Andrew H-J Wang
Structural basis of inhibition specificities of 3C and 3C-like proteases by zinc-coordinating and peptidomimetic compounds.
The Journal of biological chemistry 2009;284(12):7646-55.
2009: Jhe-Le Tu; Ko-Hsin Chin; Andrew H-J Wang; Shan-Ho Chou
Unique GTP-binding pocket and allostery of uridylate kinase from a gram-negative phytopathogenic bacterium.
Journal of molecular biology 2009;385(4):1113-26.
2009: Yu-Wei Chang; Tzu-Ping Ko; Chien-Der Lee; Yuan-Chih Chang; Kuei-Ann Lin; Chia-Seng Chang; Andrew H-J Wang; Ting-Fang Wang
Three new structures of left-handed RADA helical filaments: structural flexibility of N-terminal domain is critical for recombinase activity.
PloS one 2009;4(3):e4890.
2008: Han-Ching Wang; Han-Ching Wang; Tzu-Ping Ko; Yu-May Lee; Jiann Horng Leu; Chun-Han Ho; Wei-Pang Huang; Chu-Fang Lo; Andrew H-J Wang
White spot syndrome virus protein ICP11: A histone-binding DNA mimic that disrupts nucleosome assembly.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(52):20758-63.
2008: Cheng-Nan Chen; Ko-Hsin Chin; Andrew H-J Wang; Shan-Ho Chou
The first crystal structure of gluconolactonase important in the glucose secondary metabolic pathways.
Journal of molecular biology 2008;384(3):604-14.
2008: Yi-Yun Chen; Hsing-Mao Chu; Kuan-Ting Pan; Chun-Hung Teng; Danny Ling Wang; Andrew H-J Wang; Kay-Hooi Khoo; Tzu-Ching Meng
Cysteine S-nitrosylation protects protein-tyrosine phosphatase 1B against oxidation-induced permanent inactivation.
The Journal of biological chemistry 2008;283(50):35265-72.
2008: Yu-Hauh Wu; Tzu-Ping Ko; Rey-Ting Guo; Su-Ming Hu; Lee-Ming Chuang; Andrew H-J Wang
Structural basis for catalytic and inhibitory mechanisms of human prostaglandin reductase PTGR2.
Structure (London, England : 1993) 2008;16(11):1714-23.
2008: Ting-Fang Wang; Yuan-Chih Chang; Chien-Der Lee; Litzu Chen; Chia-Seng Chang; Andrew H-J Wang
Authors' reply to correspondence from Egelman.
BioEssays : news and reviews in molecular, cellular and developmental biology 2008;30(11-12):1254-5.
2008: Rong Cao; Cammy K-M Chen; Rey-Ting Guo; Andrew H-J Wang; Eric Oldfield
Structures of a potent phenylalkyl bisphosphonate inhibitor bound to farnesyl and geranylgeranyl diphosphate synthases.
Proteins 2008;73(2):431-9.
2008: Cheng-Jen Liao; Ko-Hsin Chin; Chao-Hsiung Lin; Peter Shi-Fong Tsai; Ping-Chiang Lyu; Chiu-Chung Young; Andrew H-J Wang; Shan-Ho Chou
Crystal structure of DFA0005 complexed with alpha-ketoglutarate: a novel member of the ICL/PEPM superfamily from alkali-tolerant Deinococcus ficus.
Proteins 2008;73(2):362-71.
2008: Cammy K-M Chen; Michael P Hudock; Yonghui Zhang; Rey-Ting Guo; Rong Cao; Joo Hwan No; Po-Huang Liang; Tzu-Ping Ko; Tao-Hsin Chang; Shiou-Chi Chang; Yongcheng Song; Jordan Axelson; Anup Kumar; Andrew H-J Wang; Eric Oldfield
Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation.
Journal of medicinal chemistry 2008;51(18):5594-607.
2008: Chi-Shu Sun; Kuan-Ta Wu; Hao-Hsien Lee; Yih-Huei Uen; Yu-Feng Tian; Cheng-Chen Tzeng; Andrew H-J Wang; Chia-Ju Cheng; Sun-Lung Tsai
Anti-sense morpholino oligonucleotide assay shows critical involvement for NF-kappaB activation in the production of Wnt-1 protein by HepG2 cells: oncology implications.
Journal of biomedical science 2008;15(5):633-43.
2008: Pao-Chi Liao; Andrew H-J Wang; Shui-Tein Chen
Taiwan proteomics society: an organization affiliated with HUPO.
Molecular & cellular proteomics : MCP 2008;7(8):1584-5.
2008: Wei-Ting Kuo; Ko-Hsin Chin; Wen-Ting Lo; Andrew H-J Wang; Shan-Ho Chou
Crystal structure of the C-terminal domain of a flagellar hook-capping protein from Xanthomonas campestris.
Journal of molecular biology 2008;381(1):189-99.
2008: Shu-Yu Lin; Yi-Yun Chen; Yao-Yun Fan; Chia-Wei Lin; Shui-Tsung Chen; Andrew H-J Wang; Kay-Hooi Khoo
Precise mapping of increased sialylation pattern and the expression of acute phase proteins accompanying murine tumor progression in BALB/c mouse by integrated sera proteomics and glycomics.
Journal of proteome research 2008;7(8):3293-303.
2008: Kai-Fa Huang; Yu-Ruei Wang; En-Cheng Chang; Tsung-Lin Chou; Andrew H-J Wang
A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.
The Biochemical journal 2008;411(1):181-90.
2008: Chia-I Liu; George Y Liu; Yongcheng Song; Fenglin Yin; Mary E Hensler; Wen-Yih Jeng; Victor Nizet; Andrew H-J Wang; Eric Oldfield
A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence.
Science (New York, N.Y.) 2008;319(5868):1391-4.
2008: Wen-Yih Jeng; Tzu-Ping Ko; Chia-I Liu; Rey-Ting Guo; Chien-Liang Liu; Hui-Lin Shr; Andrew H-J Wang
Crystal structure of IcaR, a repressor of the TetR family implicated in biofilm formation in Staphylococcus epidermidis.
Nucleic acids research 2008;36(5):1567-77.
2008: Natalie G Ahn; Andrew H-J Wang
Proteomics and genomics: perspectives on drug and target discovery.
Current opinion in chemical biology 2008;12(1):1-3.
2008: Hsing-Ju Wu; Andrew H-J Wang; Michael P Jennings
Discovery of virulence factors of pathogenic bacteria.
Current opinion in chemical biology 2008;12(1):93-101.
2008: Chih-Jung Kuo; Rey-Ting Guo; I-Lin Lu; Hun-Ge Liu; Su-Ying Wu; Tzu-Ping Ko; Andrew H-J Wang; Po-Huang Liang
Structure-based inhibitors exhibit differential activities against Helicobacter pylori and Escherichia coli undecaprenyl pyrophosphate synthases.
Journal of biomedicine & biotechnology 2008;2008():841312.
2008: Ting-Fang Wang; Li-Tzu Chen; Andrew H-J Wang
Right or left turn? RecA family protein filaments promote homologous recombination through clockwise axial rotation.
BioEssays : news and reviews in molecular, cellular and developmental biology 2008;30(1):48-56.
2007: Cheng-Chung Lee; Chih-Jung Kuo; Min-Feng Hsu; Po-Huang Liang; Jim-Min Fang; Jiun-Jie Shie; Andrew H-J Wang
Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors.
FEBS letters 2007;581(28):5454-8.
2007: Ko-Hsin Chin; Ying-Der Tsai; Nei-Li Chan; Kai-Fa Huang; Andrew H-J Wang; Shan-Ho Chou
The crystal structure of XC1258 from Xanthomonas campestris: a putative procaryotic Nit protein with an arsenic adduct in the active site.
Proteins 2007;69(3):665-71.
2007: Yi-Ming Shao; Wen-Bin Yang; Hung-Pin Peng; Min-Feng Hsu; Keng-Chang Tsai; Tun-Hsun Kuo; Andrew H-J Wang; Po-Huang Liang; Chun-Hung Lin; An-Suei Yang; Chi-Huey Wong
Structure-based design and synthesis of highly potent SARS-CoV 3CL protease inhibitors.
Chembiochem : a European journal of chemical biology 2007;8(14):1654-7.
2007: Ko-Hsin Chin; Sz-Kai Ruan; Andrew H-J Wang; Shan-Ho Chou
XC5848, an ORFan protein from Xanthomonas campestris, adopts a novel variant of Sm-like motif.
Proteins 2007;68(4):1006-10.
2007: Ta-Wei Lin; Chi-Wen Lo; Su-Yuan Lai; Ruey-Jane Fan; Chao-Jung Lo; Yu-Mei Chou; Rekha Thiruvengadam; Andrew H-J Wang; Min-Ying Wang
Chicken heat shock protein 90 is a component of the putative cellular receptor complex of infectious bursal disease virus.
Journal of virology 2007;81(16):8730-41.
2007: Wen-Ling Chou; Lee-Ming Chuang; Chi-Chi Chou; Andrew H-J Wang; John A Lawson; garret fitzgerald; Zee-Fen Chang
Identification of a novel prostaglandin reductase reveals the involvement of prostaglandin E2 catabolism in regulation of peroxisome proliferator-activated receptor gamma activation.
The Journal of biological chemistry 2007;282(25):18162-72.
2007: Rey-Ting Guo; Rong Cao; Po-Huang Liang; Tzu-Ping Ko; Tao-Hsin Chang; Michael P Hudock; Wen-Yih Jeng; Cammy K-M Chen; Yonghui Zhang; Yongcheng Song; Chih-Jung Kuo; Fenglin Yin; Eric Oldfield; Andrew H-J Wang
Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(24):10022-7.
2007: Jhe-Le Tu; Ko-Hsin Chin; Andrew H-J Wang; Shan-Ho Chou
The crystallization of apo-form UMP kinase from Xanthomonas campestris is significantly improved in a strong magnetic field.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 5):438-42.
2007: He-Hsuan Hsiao; Hsin-Yu Hsieh; Chi-Chi Chou; Shu-Yu Lin; Andrew H-J Wang; Kay-Hooi Khoo
Concerted experimental approach for sequential mapping of peptides and phosphopeptides using C18-functionalized magnetic nanoparticles.
Journal of proteome research 2007;6(4):1313-24.
2007: Han-Yu Sun; Shu-Wha Lin; Tzu-Ping Ko; Jia-Fu Pan; Chia-Ling Liu; Chun-Nan Lin; Andrew H-J Wang; Chun-Hung Lin
Structure and mechanism of Helicobacter pylori fucosyltransferase. A basis for lipopolysaccharide variation and inhibitor design.
The Journal of biological chemistry 2007;282(13):9973-82.
2007: Hsing-Mao Chu; Andrew H-J Wang
Enzyme-substrate interactions revealed by the crystal structures of the archaeal Sulfolobus PTP-fold phosphatase and its phosphopeptide complexes.
Proteins 2007;66(4):996-1003.
2007: Wang-Jing Liu; Yun-Shiang Chang; Andrew H-J Wang; Guang-Hsiung Kou; Chu-Fang Lo
White spot syndrome virus annexes a shrimp STAT to enhance expression of the immediate-early gene ie1.
Journal of virology 2007;81(3):1461-71.
2007: Li-Tzu Chen; Tzu-Ping Ko; Yu-Wei Chang; Kuei-An Lin; Andrew H-J Wang; Ting-Fang Wang
Structural and functional analyses of five conserved positively charged residues in the L1 and N-terminal DNA binding motifs of archaeal RADA protein.
PloS one 2007;2(9):e858.
2007: Li-Tzu Chen; Tzu-Ping Ko; Yuan-Chih Chang; Kuei-An Lin; Chia-Seng Chang; Andrew H-J Wang; Ting-Fang Wang
Crystal structure of the left-handed archaeal RadA helical filament: identification of a functional motif for controlling quaternary structures and enzymatic functions of RecA family proteins.
Nucleic acids research 2007;35(6):1787-801.
2007: Han-Ching Wang; Han-Ching Wang; Jiann Horng Leu; Guang-Hsiung Kou; Andrew H-J Wang; Chu-Fang Lo
Protein expression profiling of the shrimp cellular response to white spot syndrome virus infection.
Developmental and comparative immunology 2007;31(7):672-86.
2007: Sz-Kai Ruan; Ko-Hsin Chin; Hui-Lin Shr; Ping-Chiang Lyu; Andrew H-J Wang; Shan-Ho Chou
Preliminary X-ray analysis of XC5848, a hypothetical ORFan protein with an Sm-like motif from Xanthomonas campestris.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 1):30-3.
2007: Thomas D Pfister; Amir Y Mirarefi; Alan J Gengenbach; Xuan Zhao; Connor Danstrom; Nicole Conatser; Yi-Gui Gao; Howard Robinson; Charles F Zukoski; Andrew H-J Wang; Yi Lu
Kinetic and crystallographic studies of a redesigned manganese-binding site in cytochrome c peroxidase.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2007;12(1):126-37.
2006: Chien-Hua Pai; Bing-Yu Chiang; Tzu-Ping Ko; Chia-Cheng Chou; Cheong-Meng Chong; Fang-Jiun Yen; Shoujun Chen; James K Coward; Andrew H-J Wang; Chun-Hung Lin
Dual binding sites for translocation catalysis by Escherichia coli glutathionylspermidine synthetase.
The EMBO journal 2006;25(24):5970-82.
2006: Wen-Ting Lo; Ko-Hsin Chin; Hui-Lin Shr; Fei Philip Gao; Ping-Chiang Lyu; Andrew H-J Wang; Shan-Ho Chou
Crystallization and preliminary X-ray analysis of XC1015, a histidine triad-like protein from Xanthomonas campestris.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 12):1263-5.
2006: Ko-Hsin Chin; Chao-Yu Yang; Chia-Cheng Chou; Andrew H-J Wang; Shan-Ho Chou
The crystal structure of XC847 from Xanthomonas campestris: a 3'-5' oligoribonuclease of DnaQ fold family with a novel opposingly shifted helix.
Proteins 2006;65(4):1036-40.
2006: Ko-Hsin Chin; Chia-Cheng Chou; Andrew H-J Wang; Shan-Ho Chou
Crystal structure of XC5357 from Xanthomonas campestris: a putative tetracenomycin polyketide synthesis protein adopting a novel cupin subfamily structure.
Proteins 2006;65(4):1046-50.
2006: Ryu Tashiro; Andrew H-J Wang; Hiroshi Sugiyama
Photoreactivation of DNA by an archaeal nucleoprotein Sso7d.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(45):16655-9.
2006: Chien-Hung Lin; Ko-Hsin Chin; Fei Philip Gao; Ping-Chiang Lyu; Hui-Lin Shr; Andrew H-J Wang; Shan-Ho Chou
Cloning, crystallization and preliminary X-ray studies of XC2981 from Xanthomonas campestris, a putative CutA1 protein involved in copper-ion homeostasis.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 11):1113-5.
2006: Kuo-Cheng Chio; Ko-Hsin Chin; Fei Philip Gao; Ping-Chiang Lyu; Hui-Lin Shr; Andrew H-J Wang; Shan-Ho Chou
The cloning, crystallization and preliminary X-ray analysis of XC2113, a YaeQ protein from Xanthomonas campestris.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 10):1046-8.
2006: Ying-Der Tsai; Ko-Hsin Chin; Hui-Lin Shr; Fei Philip Gao; Ping-Chiang Lyu; Andrew H-J Wang; Shan-Ho Chou
Cloning, crystallization and preliminary X-ray study of XC1258, a CN-hydrolase superfamily protein from Xanthomonas campestris.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 10):999-1002.
2006: Ko-Hsin Chin; Zhi-Le Tu; Juo-Ning Li; Chia-Cheng Chou; Andrew H-J Wang; Shan-Ho Chou
The crystal structure of XC1739: a putative multiple antibiotic-resistance repressor (MarR) from Xanthomonas campestris at 1.8 A resolution.
Proteins 2006;65(1):239-42.
2006: Ko-Hsin Chin; Chia-Cheng Chou; Andrew H-J Wang; Shan-Ho Chou
Crystal structure of a putative acyl-CoA thioesterase from Xanthomonas campestris (XC229) adopts a tetrameric hotdog fold of epsilongamma mode.
Proteins 2006;64(3):823-6.
2006: Syaulan Yang; Shu-Jen Chen; Min-Feng Hsu; Jen-Dar Wu; Chien-Te K Tseng; Yu-Fan Liu; Hua-Chien Chen; Chun-Wei Kuo; Chi-Shen Wu; Li-Wen Chang; Wen-Chang Chen; Shao-Ying Liao; Teng-Yuan Chang; Hsin-Hui Hung; Hui-Lin Shr; Cheng-Yuan Liu; Yu-An Huang; Ling-Yin Chang; Jen-Chi Hsu; Clarence Peters; Andrew H-J Wang; Ming-Chu Hsu
Synthesis, crystal structure, structure-activity relationships, and antiviral activity of a potent SARS coronavirus 3CL protease inhibitor.
Journal of medicinal chemistry 2006;49(16):4971-80.
2006: Cheng-Chung Lee; Tzu-Ping Ko; Chia-Cheng Chou; Masato Yoshimura; Shyue-Ru Doong; Min-Ying Wang; Andrew H-J Wang
Crystal structure of infectious bursal disease virus VP2 subviral particle at 2.6A resolution: implications in virion assembly and immunogenicity.
Journal of structural biology 2006;155(1):74-86.
2006: Yi-Hung Lin; Hsin-Tai Li; Yen-Chieh Huang; Yin-Cheng Hsieh; Hong-Hsiang Guan; Ming-Yih Liu; Tschining Chang; Andrew H-J Wang; Chun-Jung Chen
Purification, crystallization and preliminary X-ray crystallographic analysis of rice Bowman-Birk inhibitor from Oryza sativa.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 6):522-4.
2006: Chao Yu Yang; Ko-Hsin Chin; Chia Cheng Chou; Andrew H-J Wang; Shan-Ho Chou
Structure of XC6422 from Xanthomonas campestris at 1.6 A resolution: a small serine alpha/beta-hydrolase.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 6):498-503.
2006: Tao-Hsin Chang; Rey-Ting Guo; Tzu-Ping Ko; Andrew H-J Wang; Po-Huang Liang
Crystal structure of type-III geranylgeranyl pyrophosphate synthase from Saccharomyces cerevisiae and the mechanism of product chain length determination.
The Journal of biological chemistry 2006;281(21):14991-5000.
2006: Martin K Safo; Tzu-Ping Ko; Faik N Musayev; Qixun Zhao; Andrew H-J Wang; Gordon L Archer
Structure of the MecI repressor from Staphylococcus aureus in complex with the cognate DNA operator of mec.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 4):320-4.
2006: Jyh-Ming Tsai; Han-Ching Wang; Jiann Horng Leu; Andrew H-J Wang; Ying Zhuang; Peter J Walker; Guang-Hsiung Kou; Chu-Fang Lo
Identification of the nucleocapsid, tegument, and envelope proteins of the shrimp white spot syndrome virus virion.
Journal of virology 2006;80(6):3021-9.
2006: Ting-Fang Wang; Andrew H-J Wang
Induction and screening of soluble fusion proteins in bacterial cells.
CSH protocols 2006;2006(1):.
2006: Ting-Fang Wang; Andrew H-J Wang
Preparation of sticky-end PCR products and ligation into expression vectors for high-throughput screening of soluble recombinant proteins.
CSH protocols 2006;2006(1):.
2006: Ting-Fang Wang; Andrew H-J Wang
Preparation of vectors for high-throughput screening of soluble recombinant proteins.
CSH protocols 2006;2006(1):.
2006: Ryu Tashiro; Andrew H-J Wang; Hiroshi Sugiyama
Detection of photoinduced electron transfer from Sso7d to DNA.
Nucleic acids symposium series (2004) 2006;(50):149-50.
2006: Tzong-Hsien Lee; Dar-In Tai; Cha-Ju Cheng; Chi-Shu Sun; Ching-Yih Lin; Ming-Jen Sheu; Wei-Ping Lee; Cheng-Yuan Peng; Andrew H-J Wang; Sun-Lung Tsai
Enhanced nuclear factor-kappa B-associated Wnt-1 expression in hepatitis B- and C-related hepatocarcinogenesis: identification by functional proteomics.
Journal of biomedical science 2006;13(1):27-39.
2005: Han-Yu Sun; Tzu-Ping Ko; Chih-Jung Kuo; Rey-Ting Guo; Chia-Cheng Chou; Po-Huang Liang; Andrew H-J Wang
Homodimeric hexaprenyl pyrophosphate synthase from the thermoacidophilic crenarchaeon Sulfolobus solfataricus displays asymmetric subunit structures.
Journal of bacteriology 2005;187(23):8137-48.
2005: Yan-You Wu; Ko-Hsin Chin; Chia-Cheng Chou; Cheng-Chung Lee; Hui-Lin Shr; Fei Philip Gao; Ping-Chiang Lyu; Andrew H-J Wang; Shan-Ho Chou
Cloning, purification, crystallization and preliminary X-ray crystallographic analysis of XC847, a 3'-5' oligoribonuclease from Xanthomonas campestris.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 10):902-5.
2005: Kai-Fa Huang; Yi-Liang Liu; Wei-Ju Cheng; Tzu-Ping Ko; Andrew H-J Wang
Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(37):13117-22.
2005: Min-Feng Hsu; Chih-Jung Kuo; Kai-Ti Chang; Hui-Chuan Chang; Chia-Cheng Chou; Tzu-Ping Ko; Hui-Lin Shr; Gu-Gang Chang; Andrew H-J Wang; Po-Huang Liang
Mechanism of the maturation process of SARS-CoV 3CL protease.
The Journal of biological chemistry 2005;280(35):31257-66.
2005: Kai-Fa Huang; Yi-Liang Liu; Andrew H-J Wang
Cloning, expression, characterization, and crystallization of a glutaminyl cyclase from human bone marrow: a single zinc metalloenzyme.
Protein expression and purification 2005;43(1):65-72.
2005: Sz-Wei Wu; Tzu-Ping Ko; Chia-Cheng Chou; Andrew H-J Wang
Design and characterization of a multimeric DNA binding protein using Sac7d and GCN4 as templates.
Proteins 2005;60(4):617-28.
2005: Zhi-Le Tu; Juo-Ning Li; Ko-Hsin Chin; Chia-Cheng Chou; Cheng-Chung Lee; Hui-Lin Shr; Ping-Chiang Lyu; Fei Philip Gao; Andrew H-J Wang; Shan-Ho Chou
Cloning, expression, crystallization and preliminary X-ray analysis of a putative multiple antibiotic resistance repressor protein (MarR) from Xanthomonas campestris.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 7):706-8.
2005: Chao-Yu Yang; Ko-Hsin Chin; Chia-Cheng Chou; Hui-Lin Shr; Fei Philip Gao; Ping-Chiang Lyu; Andrew H-J Wang; Shan-Ho Chou
Cloning, purification crystallization and preliminary X-ray characterization of a conserved hypothetical protein XC6422 from Xanthomonas campestris.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 7):703-5.
2005: Ko-Hsin Chin; Chia-Cheng Chou; Cheng-Chung Lee; Hui-Lin Shr; Ping-Chiang Lyu; Andrew H-J Wang; Shan-Ho Chou
Preparation, crystallization and preliminary X-ray analysis of XC2382, an ApaG protein of unknown structure from Xanthomonas campestris.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 7):700-2.
2005: Chiao-Li Chu; Ko-Hsin Chin; Fu-Yang Lin; Chia-Cheng Chou; Cheng-Chung Lee; Hui-Lin Shr; Ping-Chiang Lyu; Andrew H-J Wang; Shan-Ho Chou
A putative polyketide-synthesis protein XC5357 from Xanthomonas campestris: heterologous expression, crystallization and preliminary X-ray analysis.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 7):697-9.
2005: Ko-Hsin Chin; Wei-Tien Kuo; Chia-Cheng Chou; Hui-Lin Shr; Ping-Chiang Lyu; Andrew H-J Wang; Shan-Ho Chou
Cloning, purification, crystallization and preliminary X-ray analysis of XC229, a conserved hypothetical protein from Xanthomonas campestris.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 7):694-6.
2005: Ko-Hsin Chin; Zhao-Wei Huang; Kun-Chou Wei; Chia-Cheng Chou; Cheng-Chung Lee; Hui-Lin Shr; Fei Philip Gao; Ping-Chiang Lyu; Andrew H-J Wang; Shan-Ho Chou
Preparation, crystallization and preliminary X-ray characterization of a conserved hypothetical protein XC1692 from Xanthomonas campestris.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 7):691-3.
2005: Yi-Yun Chen; Shu-Yu Lin; Yuh-Ying Yeh; He-Hsuan Hsiao; Chi-Yue Wu; Shui-Tein Chen; Andrew H-J Wang
A modified protein precipitation procedure for efficient removal of albumin from serum.
Electrophoresis 2005;26(11):2117-27.
2005: Rey-Ting Guo; Tzu-Ping Ko; Annie P-C Chen; Chih-Jung Kuo; Andrew H-J Wang; Po-Huang Liang
Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis.
The Journal of biological chemistry 2005;280(21):20762-74.
2005: Shan-Ho Chou; Ko-Hsin Chin; Andrew H-J Wang
DNA aptamers as potential anti-HIV agents.
Trends in biochemical sciences 2005;30(5):231-4.
2005: Yan-Ping Shih; Hui-Chung Wu; Su-Ming Hu; Ting-Fang Wang; Andrew H-J Wang
Self-cleavage of fusion protein in vivo using TEV protease to yield native protein.
Protein science : a publication of the Protein Society 2005;14(4):936-41.
2005: Tswen-Kei Tang; Mark P-J Wu; Shui-Tein Chen; Ming-Hon Hou; Ming-Hsiang Hong; Fu-Ming Pan; Hui-Ming Yu; Jenn-Han Chen; Chen-Wen Yao; Andrew H-J Wang
Biochemical and immunological studies of nucleocapsid proteins of severe acute respiratory syndrome and 229E human coronaviruses.
Proteomics 2005;5(4):925-37.
2005: Martin K Safo; Qixun Zhao; Tzu-Ping Ko; Faik N Musayev; Howard Robinson; Neel Scarsdale; Andrew H-J Wang; Gordon L Archer
Crystal structures of the BlaI repressor from Staphylococcus aureus and its complex with DNA: insights into transcriptional regulation of the bla and mec operons.
Journal of bacteriology 2005;187(5):1833-44.
2005: Annie P-C Chen; Sing-Yang Chang; Yu-Chung Lin; Yang-Sheng Sun; Chao-Tsen Chen; Andrew H-J Wang; Po-Huang Liang
Substrate and product specificities of cis-type undecaprenyl pyrophosphate synthase.
The Biochemical journal 2005;386(Pt 1):169-76.
2005: Ming-Hon Hou; Andrew H-J Wang
Mithramycin forms a stable dimeric complex by chelating with Fe(II): DNA-interacting characteristics, cellular permeation and cytotoxicity.
Nucleic acids research 2005;33(4):1352-61.
2005: Chin-Yu Chen; Tzu-Ping Ko; Ting-Wan Lin; Chia-Cheng Chou; Chun-Jung Chen; Andrew H-J Wang
Probing the DNA kink structure induced by the hyperthermophilic chromosomal protein Sac7d.
Nucleic acids research 2005;33(1):430-8.
2005: Jiann Horng Leu; Jyh-Ming Tsai; Han-Ching Wang; Andrew H-J Wang; Chung-Hsiung Wang; Guang-Hsiung Kou; Chu-Fang Lo
The unique stacked rings in the nucleocapsid of the white spot syndrome virus virion are formed by the major structural protein VP664, the largest viral structural protein ever found.
Journal of virology 2005;79(1):140-9.
2004: Chun-Hua Hsu; Tzu-Ping Ko; Hui-Ming Yu; Tswen-Kei Tang; Shui-Tein Chen; Andrew H-J Wang
Immunological, structural, and preliminary X-ray diffraction characterizations of the fusion core of the SARS-coronavirus spike protein.
Biochemical and biophysical research communications 2004;324(2):761-7.
2004: Hsing-Mao Chu; Rey-Ting Guo; Ting-Wan Lin; Chia-Cheng Chou; Hui-Lin Shr; Hui-Lin Lai; Tsung-Yin Tang; Kuo-Joan Cheng; Brent L Selinger; Andrew H-J Wang
Structures of Selenomonas ruminantium phytase in complex with persulfated phytate: DSP phytase fold and mechanism for sequential substrate hydrolysis.
Structure (London, England : 1993) 2004;12(11):2015-24.
2004: Ming-Hui Lee; Chih-Hsiang Leng; Yuan-Chih Chang; Chia-Cheng Chou; Yi-Kai Chen; Fu-Fei Hsu; Chia-Seng Chang; Andrew H-J Wang; Ting-Fang Wang
Self-polymerization of archaeal RadA protein into long and fine helical filaments.
Biochemical and biophysical research communications 2004;323(3):845-51.
2004: Wen-Chen Huang; Tzu-Ping Ko; Steven S-L Li; Andrew H-J Wang
Crystal structures of the human SUMO-2 protein at 1.6 A and 1.2 A resolution: implication on the functional differences of SUMO proteins.
European journal of biochemistry / FEBS 2004;271(20):4114-22.
2004: Jyh-Ming Tsai; Han-Ching Wang; Jiann Horng Leu; He-Hsuan Hsiao; Andrew H-J Wang; Guang-Hsiung Kou; Chu-Fang Lo
Genomic and proteomic analysis of thirty-nine structural proteins of shrimp white spot syndrome virus.
Journal of virology 2004;78(20):11360-70.
2004: Tung-Liang Chung; He-Hsuan Hsiao; Yuh-Ying Yeh; Hui-Ling Shia; Yi-Ling Chen; Po-Huang Liang; Andrew H-J Wang; Kay-Hooi Khoo; Steven Shoei-Lung Li
In vitro modification of human centromere protein CENP-C fragments by small ubiquitin-like modifier (SUMO) protein: definitive identification of the modification sites by tandem mass spectrometry analysis of the isopeptides.
The Journal of biological chemistry 2004;279(38):39653-62.
2004: Lubomír Dostál; Chin-Yu Chen; Andrew H-J Wang; Heinz Welfle
Partial B-to-A DNA transition upon minor groove binding of protein Sac7d monitored by Raman spectroscopy.
Biochemistry 2004;43(30):9600-9.
2004: Tzu-Ping Ko; Hsing-Mao Chu; Chin-Yu Chen; Chia-Cheng Chou; Andrew H-J Wang
Structures of the hyperthermophilic chromosomal protein Sac7d in complex with DNA decamers.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 8):1381-7.
2004: Yi-Kai Chen; Chih-Hsiang Leng; Heidi A Olivares; Ming-Hui Lee; Yuan-Chih Chang; Wen-Mei Kung; Shih-Chieh Ti; Yu-Hui Lo; Andrew H-J Wang; Chia-Seng Chang; Douglas K Bishop; Yi-Ping Hsueh; Ting-Fang Wang
Heterodimeric complexes of Hop2 and Mnd1 function with Dmc1 to promote meiotic homolog juxtaposition and strand assimilation.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(29):10572-7.
2004: Rey-Ting Guo; Chih-Jung Kuo; Tzu-Ping Ko; Chia-Cheng Chou; Po-Huang Liang; Andrew H-J Wang
A molecular ruler for chain elongation catalyzed by octaprenyl pyrophosphate synthase and its structure-based engineering to produce unprecedented long chain trans-prenyl products.
Biochemistry 2004;43(24):7678-86.
2004: Wen-Lin Lai; Lien-Yang Chou; Chun-Yuan Ting; Ralph Kirby; Ying-Chieh Tsai; Andrew H-J Wang; Shwu-Huey Liaw
The functional role of the binuclear metal center in D-aminoacylase: one-metal activation and second-metal attenuation.
The Journal of biological chemistry 2004;279(14):13962-7.
2004: Sing-Yang Chang; Tzu-Ping Ko; Annie P-C Chen; Andrew H-J Wang; Po-Huang Liang
Substrate binding mode and reaction mechanism of undecaprenyl pyrophosphate synthase deduced from crystallographic studies.
Protein science : a publication of the Protein Society 2004;13(4):971-8.
2004: Kai-Fa Huang; Tzu-Ping Ko; Chin-Chun Hung; John Chu; Andrew H-J Wang; Shyh-Horng Chiou
Crystal structure of a platelet-agglutinating factor isolated from the venom of Taiwan habu (Trimeresurus mucrosquamatus).
The Biochemical journal 2004;378(Pt 2):399-407.
2004: Rey-Ting Guo; Chih-Jung Kuo; Chia-Cheng Chou; Tzu-Ping Ko; Hui-Lin Shr; Po-Huang Liang; Andrew H-J Wang
Crystal structure of octaprenyl pyrophosphate synthase from hyperthermophilic Thermotoga maritima and mechanism of product chain length determination.
The Journal of biological chemistry 2004;279(6):4903-12.
2004: Jr-Ming Yang; Andrew H-J Wang
Engineering a thermostable protein with two DNA-binding domains using the hyperthermophile protein Sac7d.
Journal of biomolecular structure & dynamics 2004;21(4):513-26.
2004: Ming-Hon Hou; Howard Robinson; Yi-Gui Gao; Andrew H-J Wang
Crystal structure of the [Mg2+-(chromomycin A3)2]-d(TTGGCCAA)2 complex reveals GGCC binding specificity of the drug dimer chelated by a metal ion.
Nucleic acids research 2004;32(7):2214-22.
2004: Ho-Sheng Wu; Yueh-Chun Hsieh; Ih-Jen Su; Ting-Hsiang Lin; Shu-Chun Chiu; Yu-Fen Hsu; Jih-Hui Lin; Mei-Ching Wang; Jeou-Yuan Chen; Pei-Wen Hsiao; Geen-Dong Chang; Andrew H-J Wang; Hsien-Wei Ting; Chih-Ming Chou; Chang-Jen Huang
Early detection of antibodies against various structural proteins of the SARS-associated coronavirus in SARS patients.
Journal of biomedical science 2004;11(1):117-26.
2003: Sing-Yang Chang; Yi-Kai Chen; Andrew H-J Wang; Po-Huang Liang
Identification of the active conformation and the importance of length of the flexible loop 72-83 in regulating the conformational change of undecaprenyl pyrophosphate synthase.
Biochemistry 2003;42(49):14452-9.
2003: Chih-Lei Lee; He-Hsuan Hsiao; Chia-Wei Lin; Szu-Pei Wu; Shiuan-Yi Huang; Chi-Yue Wu; Andrew H-J Wang; Kay-Hooi Khoo
Strategic shotgun proteomics approach for efficient construction of an expression map of targeted protein families in hepatoma cell lines.
Proteomics 2003;3(12):2472-86.
2003: Rey-Ting Guo; Tzu-Ping Ko; Chia-Cheng Chou; Hui-Lin Shr; Hsing-Mao Chu; Yao-Hsien Tsai; Po-Huang Liang; Andrew H-J Wang
Preliminary X-ray diffraction analysis of octaprenyl pyrophosphate synthase crystals from Thermotoga maritima and Escherichia coli.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 12):2265-8.
2003: Sing-Yang Chang; Tzu-Ping Ko; Po-Huang Liang; Andrew H-J Wang
Catalytic mechanism revealed by the crystal structure of undecaprenyl pyrophosphate synthase in complex with sulfate, magnesium, and triton.
The Journal of biological chemistry 2003;278(31):29298-307.
2003: Chia-Cheng Chou; Ting-Wan Lin; Chin-Yu Chen; Andrew H-J Wang
Crystal structure of the hyperthermophilic archaeal DNA-binding protein Sso10b2 at a resolution of 1.85 Angstroms.
Journal of bacteriology 2003;185(14):4066-73.
2003: Cheng-Chung Lee; Tzu-Ping Ko; Meng-Shiou Lee; Chia-Cheng Chou; Su-Yuan Lai; Andrew H-J Wang; Min-Ying Wang
Purification, crystallization and preliminary X-ray analysis of immunogenic virus-like particles formed by infectious bursal disease virus (IBDV) structural protein VP2.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 7):1234-7.
2003: Tzu-Ping Ko; Jing-Jer Lin; Chung-Yi Hu; Yi-Hsin Hsu; Andrew H-J Wang; Shwu-Huey Liaw
Crystal structure of yeast cytosine deaminase. Insights into enzyme mechanism and evolution.
The Journal of biological chemistry 2003;278(21):19111-7.
2003: Shan-Ho Chou; Ko-Hsin Chin; Andrew H-J Wang
Unusual DNA duplex and hairpin motifs.
Nucleic acids research 2003;31(10):2461-74.
2003: Szu-Pei Wu; Tzann-Shun Hwang; Tzu-Ping Ko; Andrew H-J Wang; Hsin Tsai
The structural interpretations of residue Ser297 in catalytic efficiency of Escherichia coli phenylalanine aminotransferase.
Biochimica et biophysica acta 2003;1647(1-2):390-4.
2003: Shwu-Huey Liaw; Shen-Jia Chen; Tzu-Ping Ko; Cheng-Sheng Hsu; Chun-Jung Chen; Andrew H-J Wang; Ying-Chieh Tsai
Crystal structure of D-aminoacylase from Alcaligenes faecalis DA1. A novel subset of amidohydrolases and insights into the enzyme mechanism.
The Journal of biological chemistry 2003;278(7):4957-62.
2003: Tzu-Ping Ko; Howard Robinson; Yi-Gui Gao; Chi-Hing C Cheng; Arthur L DeVries; Andrew H-J Wang
The refined crystal structure of an eel pout type III antifreeze protein RD1 at 0.62-A resolution reveals structural microheterogeneity of protein and solvation.
Biophysical journal 2003;84(2 Pt 1):1228-37.
2002: Ming-Hon Hou; Howard Robinson; Yi-Gui Gao; Andrew H-J Wang
Crystal structure of actinomycin D bound to the CTG triplet repeat sequences linked to neurological diseases.
Nucleic acids research 2002;30(22):4910-7.
2002: Cheng-Sheng Hsu; Shen Jia Chen; Ying Chieh Tsai; Ting-Wan Lin; Shwu-Huey Liaw; Andrew H-J Wang
Crystallization and preliminary crystallographic analysis of a D-aminoacylase from Alcaligenes faecalis DA1.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 9):1482-3.
2002: Po-Huang Liang; Tzu-Ping Ko; Andrew H-J Wang
Structure, mechanism and function of prenyltransferases.
European journal of biochemistry / FEBS 2002;269(14):3339-54.
2002: Kai-Fa Huang; Shyh-Horng Chiou; Tzu-Ping Ko; Jeu-Ming Yuann; Andrew H-J Wang
The 1.35 A structure of cadmium-substituted TM-3, a snake-venom metalloproteinase from Taiwan habu: elucidation of a TNFalpha-converting enzyme-like active-site structure with a distorted octahedral geometry of cadmium.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 7):1118-28.
2002: Yan-Ping Shih; Wen-Mei Kung; Jui-Chuan Chen; Chia-Hui Yeh; Andrew H-J Wang; Ting-Fang Wang
High-throughput screening of soluble recombinant proteins.
Protein science : a publication of the Protein Society 2002;11(7):1714-9.
2002: Kai-Fa Huang; Shyh-Horng Chiou; Tzu-Ping Ko; Andrew H-J Wang
Determinants of the inhibition of a Taiwan habu venom metalloproteinase by its endogenous inhibitors revealed by X-ray crystallography and synthetic inhibitor analogues.
European journal of biochemistry / FEBS 2002;269(12):3047-56.
2002: Takanori Oyoshi; Andrew H-J Wang; Hiroshi Sugiyama
Photoreactivity of 5-iodouracil-containing DNA-Sso7d complex in solution: the protein-induced DNA kink causes intrastrand hydrogen abstraction from the 5-methyl of thymine at the 5' side.
Journal of the American Chemical Society 2002;124(10):2086-7.
2002: Yi-Hung Chen; Annie P-C Chen; Chao-Tsen Chen; Andrew H-J Wang; Po-Huang Liang
Probing the conformational change of Escherichia coli undecaprenyl pyrophosphate synthase during catalysis using an inhibitor and tryptophan mutants.
The Journal of biological chemistry 2002;277(9):7369-76.
2001: Tzu-Ping Ko; Yi-Kai Chen; Howard Robinson; P C Tsai; Yi-Gui Gao; Annie P-C Chen; Andrew H-J Wang; Po-Huang Liang
Mechanism of product chain length determination and the role of a flexible loop in Escherichia coli undecaprenyl-pyrophosphate synthase catalysis.
The Journal of biological chemistry 2001;276(50):47474-82.
2001: Howard Robinson; Yi-Gui Gao; X Yang ; R Sanishvili; A Joachimiak; Andrew H-J Wang
Crystallographic analysis of a novel complex of actinomycin D bound to the DNA decamer CGATCGATCG.
Biochemistry 2001;40(19):5587-92.
2000: Kjell Håkansson; Andrew H-J Wang; Charles G. Miller
The structure of aspartyl dipeptidase reveals a unique fold with a Ser-His-Glu catalytic triad.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(26):14097-102.
2000: S Su; Yi-Gui Gao; Howard Robinson; Y C Liaw; Stephen P Edmondson; John W Shriver; Andrew H-J Wang
Crystal structures of the chromosomal proteins Sso7d/Sac7d bound to DNA containing T-G mismatched base-pairs.
Journal of molecular biology 2000;303(3):395-403.
2000: XL Yang; Howard Robinson; Yi-Gui Gao; Andrew H-J Wang
Binding of a macrocyclic bisacridine and ametantrone to CGTACG involves similar unusual intercalation platforms.
Biochemistry 2000;39(36):10950-7.
2000: Kjell Håkansson; D Broder; Andrew H-J Wang; Charles G. Miller
Crystallization of peptidase T from Salmonella typhimurium.
Acta crystallographica. Section D, Biological crystallography 2000;56(Pt 7):924-6.
2000: Howard Robinson; Yi-Gui Gao; R Sanishvili; A Joachimiak; Andrew H-J Wang
Hexahydrated magnesium ions bind in the deep major groove and at the outer mouth of A-form nucleic acid duplexes.
Nucleic acids research 2000;28(8):1760-6.
1999: Yi-Gui Gao; Howard Robinson; R Sanishvili; A Joachimiak; Andrew H-J Wang
Structure and recognition of sheared tandem G x A base pairs associated with human centromere DNA sequence at atomic resolution.
Biochemistry 1999;38(50):16452-60.
1999: XL Yang; R B Hubbard ; M Lee; Z F Tao; H Sugiyama; Andrew H-J Wang
Imidazole-imidazole pair as a minor groove recognition motif for T:G mismatched base pairs.
Nucleic acids research 1999;27(21):4183-90.
1999: XL Yang; Andrew H-J Wang
Structural studies of atom-specific anticancer drugs acting on DNA.
Pharmacology & therapeutics 1999;83(3):181-215.
1999: Joanna K Krueger; Bradford S McCrary; Andrew H-J Wang; John W Shriver; Jill Trewhella; Stephen P Edmondson
The solution structure of the Sac7d/DNA complex: a small-angle X-ray scattering study.
Biochemistry 1999;38(32):10247-55.
1999: X L Yang; C Kaenzig; M Lee; Andrew H-J Wang
Binding of AR-1-144, a tri-imidazole DNA minor groove binder, to CCGG sequence analyzed by NMR spectroscopy.
European journal of biochemistry / FEBS 1999;263(3):646-55.
1999: Howard Robinson; M C Ang; Yi-Gui Gao; M T Hay; Y Lu; Andrew H-J Wang
Structural basis of electron transfer modulation in the purple CuA center.
Biochemistry 1999;38(18):5677-83.
1999: Yi-Gui Gao; Howard Robinson; Andrew H-J Wang
High-resolution A-DNA crystal structures of d(AGGGGCCCCT). An A-DNA model of poly(dG) x poly(dC).
European journal of biochemistry / FEBS 1999;261(2):413-20.
1999: Takanori Oyoshi; Hiroshi Sugiyama; Andrew H-J Wang
Photoreactivity of 5-iodouracil-containing DNA-Sso7d complex.
Nucleic acids symposium series 1999;(42):171-2.
1999: Andrew H-J Wang; Howard Robinson; Yi-Gui Gao
Ultra-high resolution DNA structures.
Nucleic acids symposium series 1999;(42):151-2.
1998: Yi-Gui Gao; S Y Su; Howard Robinson; S Padmanabhan; L Lim; Bradford S McCrary; Stephen P Edmondson; John W Shriver; Andrew H-J Wang
The crystal structure of the hyperthermophile chromosomal protein Sso7d bound to DNA.
Nature structural biology 1998;5(9):782-6.
1998: XL Yang; H Sugiyama; S Ikeda; I Saito; Andrew H-J Wang
Structural studies of a stable parallel-stranded DNA duplex incorporating isoguanine:cytosine and isocytosine:guanine basepairs by nuclear magnetic resonance spectroscopy.
Biophysical journal 1998;75(3):1163-71.
1998: Howard Robinson; Yi-Gui Gao; C Bauer; C Roberts; C Switzer; Andrew H-J Wang
2'-Deoxyisoguanosine adopts more than one tautomer to form base pairs with thymidine observed by high-resolution crystal structure analysis.
Biochemistry 1998;37(31):10897-905.
1998: Yi-Gui Gao; Howard Robinson; Y Guan; Y C Liaw; J H van Boom; G A van der Marel; Andrew H-J Wang
Molecular structure of two crystal forms of cyclic triadenylic acid at 1A resolution.
Journal of biomolecular structure & dynamics 1998;16(1):69-76.
1998: R Dutta; Yi-Gui Gao; W Priebe; Andrew H-J Wang
Binding of the modified daunorubicin WP401 adjacent to a T-G base pair induces the reverse Watson-Crick conformation: crystal structures of the WP401-TGGCCG and WP401-CGG[br5C]CG complexes.
Nucleic acids research 1998;26(12):3001-5.
1998: Howard Robinson; Yi-Gui Gao; Bradford S McCrary; Stephen P Edmondson; John W Shriver; Andrew H-J Wang
The hyperthermophile chromosomal protein Sac7d sharply kinks DNA.
Nature 1998;392(6672):202-5.
1997: J Caceres-Cortes; H Sugiyama; K Ikudome; I Saito; Andrew H-J Wang
Interactions of deglycosylated cobalt(III)-pepleomycin (green form) with DNA based on NMR structural studies,.
Biochemistry 1997;36(33):9995-10005.
1997: Howard Robinson; W Priebe; J B Chaires; Andrew H-J Wang
Binding of two novel bisdaunorubicins to DNA studied by NMR spectroscopy.
Biochemistry 1997;36(29):8663-70.
1997: XL Yang; Andrew H-J Wang
Structural analysis of Z-Z DNA junctions with A:A and T:T mismatched base pairs by NMR.
Biochemistry 1997;36(14):4258-67.
1997: S Su; Yi-Gui Gao; H Zhang; T C Terwilliger; Andrew H-J Wang
Analyses of the stability and function of three surface mutants (R82C, K69H, and L32R) of the gene V protein from Ff phage by X-ray crystallography.
Protein science : a publication of the Protein Society 1997;6(4):771-80.
1997: J Caceres-Cortes; Hiroshi Sugiyama; K Ikudome; I Saito; Andrew H-J Wang
Structures of cobalt(III)-pepleomycin and cobalt(III)-deglycopepleomycin (green forms) determined by NMR studies.
European journal of biochemistry / FEBS 1997;244(3):818-28.
1996: Yi-Gui Gao; Waldemar Priebe; Andrew H-J Wang
Substitutions at C2' of daunosamine in the anticancer drug daunorubicin alter its DNA-binding sequence specificity.
European journal of biochemistry / FEBS 1996;240(2):331-5.
1996: H Zhang; M M Skinner; W S Sandberg; Andrew H-J Wang; Thomas C Terwilliger
Context dependence of mutational effects in a protein: the crystal structures of the V35I, I47V and V35I/I47V gene V protein core mutants.
Journal of molecular biology 1996;259(1):148-59.
1995: Yi-Gui Gao; Howard Robinson; J H van Boom; Andrew H-J Wang
Influence of counter-ions on the crystal structures of DNA decamers: binding of [Co(NH3)6]3+ and Ba2+ to A-DNA.
Biophysical journal 1995;69(2):559-68.
1994: M Sriram; Danzhou Yang; Yi-Gui Gao; Andrew H-J Wang
Crystal and solution structures of d(CGC[e6G]AATTCGCG)-drug complexes reveal conformational polymorphism of O6-ethyl-guanine:cytosine base pair.
Annals of the New York Academy of Sciences 1994;726():18-43; discussion 43-4.
1994: M M Skinner; H Zhang; D H Leschnitzer; Y Guan; H Bellamy; R M Sweet; Carla W Gray; R N Konings; Andrew H-J Wang; Thomas C Terwilliger
Structure of the gene V protein of bacteriophage f1 determined by multiwavelength x-ray diffraction on the selenomethionyl protein.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(6):2071-5.
1993: Y Guan; Yi-Gui Gao; Y C Liaw; Howard Robinson; Andrew H-J Wang
Molecular structure of cyclic diguanylic acid at 1 A resolution of two crystal forms: self-association, interactions with metal ion/planar dyes and modeling studies.
Journal of biomolecular structure & dynamics 1993;11(2):253-76.
1993: Yi-Gui Gao; M Sriram; W A Denny; Andrew H-J Wang
Minor groove binding of SN6999 to an alkylated DNA: molecular structure of d(CGC[e6G]AATTCGCG)-SN6999 complex.
Biochemistry 1993;32(37):9639-48.
1993: Yi-Gui Gao; M Sriram; Andrew H-J Wang
Crystallographic studies of metal ion-DNA interactions: different binding modes of cobalt(II), copper(II) and barium(II) to N7 of guanines in Z-DNA and a drug-DNA complex.
Nucleic acids research 1993;21(17):4093-101.
1993: Danzhou Yang; Y Gao; Howard Robinson; G A van der Marel; J H van Boom; Andrew H-J Wang
Structural effects of the C2-methylhypoxanthine:cytosine base pair in B-DNA: A combined NMR and X-ray diffraction study of d(CGC[m2I]AATTCGCG).
Biochemistry 1993;32(33):8672-81.
1993: T N Jaishree; Andrew H-J Wang
NMR studies of pH-dependent conformational polymorphism of alternating (C-T)n sequences.
Nucleic acids research 1993;21(16):3839-44.
1993: H Robinson; Andrew H-J Wang
5'-CGA sequence is a strong motif for homo base-paired parallel-stranded DNA duplex as revealed by NMR analysis.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(11):5224-8.
1993: H Zhang; Yi-Gui Gao; G A van der Marel; J H van Boom; Andrew H-J Wang
Simultaneous incorporations of two anticancer drugs into DNA. The structures of formaldehyde-cross-linked adducts of daunorubicin-d(CG(araC)GCG) and doxorubicin-d(CA(araC)GTG) complexes at high resolution.
The Journal of biological chemistry 1993;268(14):10095-101.
1993: T N Jaishree; G A van der Marel; J H van Boom; Andrew H-J Wang
Structural influence of RNA incorporation in DNA: quantitative nuclear magnetic resonance refinement of d(CG)r(CG)d(CG) and d(CG)r(C)d(TAGCG).
Biochemistry 1993;32(18):4903-11.
1993: Y Guan; R Sakai; K L Rinehart; Andrew H-J Wang
Molecular and crystal structures of ecteinascidins: potent antitumor compounds from the Caribbean tunicate Ecteinascidia turbinata.
Journal of biomolecular structure & dynamics 1993;10(5):793-818.
1993: James M Benevides; Andrew H-J Wang; George Thomas
Demonstration of Z-d(5BrCGAT5BrCG) and B-d(CGCGATCGCG) form crystal structures in DNA-cobalt hexammine complexes by Kr 647.1 nm excitation of Raman spectra.
Nucleic acids research 1993;21(6):1433-8.
1992: M Sriram; G A van der Marel; H L Roelen; J H van Boom; Andrew H-J Wang
Structural consequences of a carcinogenic alkylation lesion on DNA: effect of O6-ethylguanine on the molecular structure of the d(CGC[e6G]AATTCGCG)-netropsin complex.
Biochemistry 1992;31(47):11823-34.
1992: H Robinson; G A van der Marel; J H van Boom; Andrew H-J Wang
Unusual DNA conformation at low pH revealed by NMR: parallel-stranded DNA duplex with homo base pairs.
Biochemistry 1992;31(43):10510-7.
1992: H Zhang; G A van der Marel; J H van Boom; Andrew H-J Wang
Conformational perturbation of the anticancer nucleotide arabinosylcytosine on Z-DNA: molecular structure of (araC-dG)3 at 1.3 A resolution.
Biopolymers 1992;32(11):1559-69.
1992: Howard Robinson; Andrew H-J Wang
A simple spectral-driven procedure for the refinement of DNA structures by NMR spectroscopy.
Biochemistry 1992;31(13):3524-33.
1992: M Sriram; G A van der Marel; H L Roelen; J H van Boom; Andrew H-J Wang
Conformation of B-DNA containing O6-ethyl-G-C base pairs stabilized by minor groove binding drugs: molecular structure of d(CGC[e6G]AATTCGCG complexed with Hoechst 33258 or Hoechst 33342.
The EMBO journal 1992;11(1):225-32.
1991: Yi-Gui Gao; G A van der Marel; J H van Boom; Andrew H-J Wang
Molecular structure of a DNA decamber containing an anticancer nucleoside arabinosylcytosine: conformational perturbation by arabinosylcytosine in B-DNA.
Biochemistry 1991;30(41):9922-31.
1991: M Sriram; Y C Liaw; Yi-Gui Gao; Andrew H-J Wang
Molecular structure of antitumor drug steffimycin and modelling of its binding to DNA.
Journal of biomolecular structure & dynamics 1991;9(2):251-69.
1991: Yi-Gui Gao; Andrew H-J Wang
Influence of aglycone modifications on the binding of anthracycline drugs to DNA: the molecular structure of idarubicin and 4-O-demethyl-11-deoxydoxorubicin complexed to d(CGATCG).
Anti-cancer drug design 1991;6(3):137-49.
1991: Yi-Gui Gao; Y C Liaw; Y K Li; G A van der Marel; J H van Boom; Andrew H-J Wang
Facile formation of a crosslinked adduct between DNA and the daunorubicin derivative MAR70 mediated by formaldehyde: molecular structure of the MAR70-d(CGTnACG) covalent adduct.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(11):4845-9.
1991: Andrew H-J Wang; Yi-Gui Gao; Y C Liaw; Y K Li
Formaldehyde cross-links daunorubicin and DNA efficiently: HPLC and X-ray diffraction studies.
Biochemistry 1991;30(16):3812-5.
1991: M Sriram; Y C Liaw; Yi-Gui Gao; Andrew H-J Wang
Comparison of two hydrated forms of sodium inosine 5'-monophosphate.
Acta crystallographica. Section C, Crystal structure communications 1991;47 ( Pt 3)():507-10.
1990: Yi-Gui Gao; Y C Liaw; Howard Robinson; Andrew H-J Wang
Binding of the antitumor drug nogalamycin and its derivatives to DNA: structural comparison.
Biochemistry 1990;29(45):10307-16.
1990: Y C Liaw; Yi-Gui Gao; Howard Robinson; G M Sheldrick; L A Sliedregt; G A van der Marel; J H van Boom; Andrew H-J Wang
Cyclic diguanylic acid behaves as a host molecule for planar intercalators.
FEBS letters 1990;264(2):223-7.
1989: Y C Liaw; Yi-Gui Gao; Howard Robinson; G A van der Marel; J H van Boom; Andrew H-J Wang
Antitumor drug nogalamycin binds DNA in both grooves simultaneously: molecular structure of nogalamycin-DNA complex.
Biochemistry 1989;28(26):9913-8.
1989: M K Teng; Y C Liaw; G A van der Marel; J H van Boom; Andrew H-J Wang
Effects of the O2' hydroxyl group on Z-DNA conformation: structure of Z-RNA and (araC)-[Z-DNA].
Biochemistry 1989;28(12):4923-8.
1989: James M Benevides; Andrew H-J Wang; G A van der Marel; J H van Boom; George Thomas
Effect of the G.T mismatch on backbone and sugar conformations of Z-DNA and B-DNA: analysis by Raman spectroscopy of crystal and solution structures of d(CGCGTG) and d(CGCGCG).
Biochemistry 1989;28(1):304-10.
1988: James M Benevides; Andrew H-J Wang; G A van der Marel; J H van Boom; George Thomas
Crystal and solution structures of the B-DNA dodecamer d(CGCAAATTTGCG) probed by Raman spectroscopy: heterogeneity in the crystal structure does not persist in the solution structure.
Biochemistry 1988;27(3):931-8.