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Binghe Wang

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Sarah K Burroughs; Stefan Kaluz; Erwin G Van Meir; Danzhu Wang; Ke Wang; Binghe Wang
Hypoxia inducible factor pathway inhibitors as anticancer therapeutics.
Bowen Ke; Nanting Ni; Weixuan Chen; Yunfeng Cheng; Chaofeng Dai; Hieu Dinh; Binghe Wang
A fluorescent probe for rapid aqueous fluoride detection and cell imaging.
Yunfeng Cheng; Chaofeng Dai; Bowen Ke; Nanting Ni; Hanjing Peng; Weixuan Chen; Binghe Wang
Rapid and specific post-synthesis modification of DNA through a biocompatible condensation of 1,2-aminothiols with 2-cyanobenzothiazole.

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All Publications

2013: Sarah K Burroughs; Stefan Kaluz; Erwin G Van Meir; Danzhu Wang; Ke Wang; Binghe Wang
Hypoxia inducible factor pathway inhibitors as anticancer therapeutics.
Future medicinal chemistry 2013;5(5):553-72.
2013: Bowen Ke; Nanting Ni; Weixuan Chen; Yunfeng Cheng; Chaofeng Dai; Hieu Dinh; Binghe Wang
A fluorescent probe for rapid aqueous fluoride detection and cell imaging.
Chemical communications (Cambridge, England) 2013;49(25):2494-6.
2013: Yunfeng Cheng; Chaofeng Dai; Bowen Ke; Nanting Ni; Hanjing Peng; Weixuan Chen; Binghe Wang
Rapid and specific post-synthesis modification of DNA through a biocompatible condensation of 1,2-aminothiols with 2-cyanobenzothiazole.
Chemistry (Weinheim an der Bergstrasse, Germany) 2013;19(12):4036-42.
2012: Zhongyu Wu; Hao Fang; Minyong Li; Binghe Wang
A new boronic acid based fluorescent reporter for catechol.
Bioorganic & medicinal chemistry letters 2012;22(23):7179-82.
2012: Peng Zhu; Nanting Ni; Hanjing Peng; Binghe Wang; Minyong Li
Novel AI-2 quorum sensing inhibitors in Vibrio harveyi identified through structure-based virtual screening.
Bioorganic & medicinal chemistry letters 2012;22(20):6413-7.
2012: Longqin Hu; Binghe Wang
In honor of Professor Lester A. Mitscher on the occasion of his 80(th) birthday.
Medicinal research reviews 2012;32(4):685-6.
2012: Weixuan Chen; Yunfeng Cheng; Binghe Wang
Dual-responsive boronate crosslinked micelles for targeted drug delivery.
Angewandte Chemie (International ed. in English) 2012;51(22):5293-5.
2012: Nanting Ni; You Feng; Sarah Laughlin; Yingji Wang; Yujun Zheng; Binghe Wang
Probing the general time scale question of boronic acid binding with sugars in aqueous solution at physiological pH.
Bioorganic & medicinal chemistry 2012;20(9):2957-61.
2012: Ying-Ju Huang; Minyong Li; Binghe Wang; Hongyun Wang; Hsiuchin Yang; Fen-Biao Gao; Phang-Cheng Tai
Fluorescein analogues inhibit SecA ATPase: the first sub-micromolar inhibitor of bacterial protein translocation.
ChemMedChem 2012;7(4):571-7.
2012: Weixuan Chen; Chaofeng Dai; Donald Hamelberg; Danzhu Wang; Binghe Wang
Clicking 1,2,4,5-tetrazine and cyclooctynes with tunable reaction rates.
Chemical communications (Cambridge, England) 2012;48(12):1736-8.
2012: Hanjing Peng; Robert Strongin; Weixuan Chen; Yunfeng Cheng; Lovemore Hakuna; Binghe Wang
Thiol reactive probes and chemosensors.
Sensors (Basel, Switzerland) 2012;12(11):15907-46.
2012: Jae Hyang Lim; Takashi Matsuno; Masanori Miyata; Soo Hyun Park; Huahao Shen; Binghe Wang; Chang-Hoon Woo; Haodong Xu; Haidong Xu; Xiangbin Xu; Chen Yan; Wenhong Zhang; Patricia Bourne; Lin Feng Chen; Yoo Duk Choi; Xin-Hua Feng; Kyung-Sun Heo; Yuxian Huang; Hirofumi Jono; Yu-Il Kim; Tomoaki Koga; Kensei Komatsu; Jiyun Lee; Jian-Dong Li
CYLD negatively regulates transforming growth factor-β-signalling via deubiquitinating Akt.
Nature communications 2012;3():771.
2011: Suazette Reid Mooring; Adnan A Jabbar; Erwin Van Meir; Yuan Liu; Narra S Devi; Hui Jin; Stefan Kaluz; Binghe Wang
Design and synthesis of novel small-molecule inhibitors of the hypoxia inducible factor pathway.
Journal of medicinal chemistry 2011;54(24):8471-89.
2011: Xiaochuan Yang; Chunhao Yang; Guojing Sun; Binghe Wang
Novel rhein analogues as potential anticancer agents.
ChemMedChem 2011;6(12):2294-301.
2011: Chaofeng Dai; Richard R Drake; O John Semmes; Dean A Troyer; Lisa H Cazares; Yong Chu; Lifang Wang; Siming L Wang; Binghe Wang
Using boronolectin in MALDI-MS imaging for the histological analysis of cancer tissue expressing the sialyl Lewis X antigen.
Chemical communications (Cambridge, England) 2011;47(37):10338-40.
2011: Lifang Wang; Siming Liu Wang; Weixuan Chen; Chaofeng Dai; Binghe Wang
Facile derivatization of azide ions using click chemistry for their sensitive detection with LC-MS.
Chemical communications (Cambridge, England) 2011;47(37):10377-9.
2011: Yunfeng Cheng; Chaofeng Dai; Shan Jin; Hanjing Peng; Shilong Zheng; Binghe Wang
Design, synthesis, and polymerase-catalyzed incorporation of click-modified boronic acid-TTP analogues.
Chemistry, an Asian journal 2011;6(10):2747-52.
2011: Hanjing Peng; Benjamin L Predmore; Yunfeng Cheng; Chaofeng Dai; Adrienne L King; David J Lefer; Binghe Wang
A fluorescent probe for fast and quantitative detection of hydrogen sulfide in blood.
Angewandte Chemie (International ed. in English) 2011;50(41):9672-5.
2011: Jing Zhao; Yan Bai; Joseph T Barbieri; Xiaodong Cheng; Lupei Du; Yuhong Du; John Horton; Fadlo R Khuri; Minyong Li; Bin Lou; Anup K Upadhyay; Binghe Wang; Lixin Zhang; Xing Zhang; Haian Fu
Discovery and structural characterization of a small molecule 14-3-3 protein-protein interaction inhibitor.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(39):16212-6.
2011: Chalet Tan; Binghe Wang; Rita G de Noronha; Narra S Devi; Adnan A Jabbar; Stefan Kaluz; Yuan Liu; Suazette Reid Mooring; K C Nicolaou; Erwin Van Meir
Sulfonamides as a new scaffold for hypoxia inducible factor pathway inhibitors.
Bioorganic & medicinal chemistry letters 2011;21(18):5528-32.
2011: Hamed Laroui; Saravanan Ayyadurai; Moiz A Charania; Sarah A Ingersoll; Yoshie Narui; khalid salaita; Shanthi V Sitaraman; Binghe Wang; Yutao Yan; Feimeng Zhou; Didier Merlin
L-Ala-γ-D-Glu-meso-diaminopimelic acid (DAP) interacts directly with leucine-rich region domain of nucleotide-binding oligomerization domain 1, increasing phosphorylation activity of receptor-interacting serine/threonine-protein kinase 2 and its interaction with nucleotide-binding oligomerization domain 1.
The Journal of biological chemistry 2011;286(35):31003-13.
2011: Lisa H Cazares; Richard R Drake; Dean A Troyer; Binghe Wang; O John Semmes
MALDI tissue imaging: from biomarker discovery to clinical applications.
Analytical and bioanalytical chemistry 2011;401(1):17-27.
2011: Chaofeng Dai; Lifang Wang; Jia Sheng; Hanjing Peng; Alexander Boryanov Draganov; Zhen Huang; Binghe Wang
The first chemical synthesis of boronic acid-modified DNA through a copper-free click reaction.
Chemical communications (Cambridge, England) 2011;47(12):3598-600.
2011: Jiang Wu; Juxian Wang; Minyong Li; Yutao Yang; Binghe Wang; Yujun Zheng
Small molecule inhibitors of histone acetyltransferase Tip60.
Bioorganic chemistry 2011;39(1):53-8.
2011: Guojun Chen; Nanting Ni; Jianfeng Zhou; Chuang Yen-Jun; Binghe Wang; Zhengwei Pan; Bingqian Xu
Fibrinogen clot induced by gold-nanoparticle in vitro.
Journal of nanoscience and nanotechnology 2011;11(1):74-81.
2010: Yunfeng Cheng; Nanting Ni; Wenqian Yang; Binghe Wang
A new class of fluorescent boronic acids that have extraordinarily high affinities for diols in aqueous solution at physiological pH.
Chemistry (Weinheim an der Bergstrasse, Germany) 2010;16(45):13528-38.
2010: Sarah Burroughs; Binghe Wang
Boronic acid-based lectin mimics (boronolectins) that can recognize cancer biomarker, the Thomsen-Friedenrich antigen.
Chembiochem : a European journal of chemical biology 2010;11(16):2245-6.
2010: Sharon King-Keller; Minyong Li; Alyssa Smith; Shilong Zheng; Gurpreet Kaur; Xiaochuan Yang; Binghe Wang; Roberto Docampo
Chemical validation of phosphodiesterase C as a chemotherapeutic target in Trypanosoma cruzi, the etiological agent of Chagas' disease.
Antimicrobial agents and chemotherapy 2010;54(9):3738-45.
2010: You Feng; Mingyong Li; Binghe Wang; Yujun Zheng
Discovery and mechanistic study of a class of protein arginine methylation inhibitors.
Journal of medicinal chemistry 2010;53(16):6028-39.
2010: Qian Yang; David Fedida; Hongjian Xu; Binghe Wang; Lupei Du; Xiaojian Wang; Minyong Li; Qidong You
Structure-based virtual screening and electrophysiological evaluation of new chemotypes of K(v)1.5 channel blockers.
ChemMedChem 2010;5(8):1353-8.
2010: Chaofeng Dai; Yunfeng Cheng; Jianmei Cui; Binghe Wang
Click reactions and boronic acids: applications, issues, and potential solutions.
Molecules (Basel, Switzerland) 2010;15(8):5768-81.
2010: Jiangying Cao; Hao Fang; Binghe Wang; Chunhua Ma; Wenfang Xu
Epidermal growth factor receptor as a target for anti-cancer agent design.
Anti-cancer agents in medicinal chemistry 2010;10(6):491-503.
2010: Qiang Wang; Fuming Xu; Jiajia Mou; Jie Zhang; Luqing Shang; Yepeng Luan; Yumei Yuan; Yingzi Liu; Minyong Li; Hao Fang; Binghe Wang; Wenfang Xu
Design, synthesis and preliminary activity evaluation of novel L-lysine derivatives as aminopeptidase N/CD13 inhibitors.
Protein and peptide letters 2010;17(7):847-53.
2010: Keng-Chang Tsai; Yu-Chen Chen; Nai-Wan Hsiao; Chao-Li Wang; Chih-Lung Lin; Yu-Ching Lee; Minyong Li; Binghe Wang
A comparison of different electrostatic potentials on prediction accuracy in CoMFA and CoMSIA studies.
European journal of medicinal chemistry 2010;45(4):1544-51.
2010: Yingjie Zhang; Jinhong Feng; Chunxi Liu; Lei Zhang; Jie Jiao; Hao Fang; Li Su; Xiaopan Zhang; Jian Zhang; Minyong Li; Binghe Wang; Wenfang Xu
Design, synthesis and preliminary activity assay of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives as novel Histone deacetylases (HDACs) inhibitors.
Bioorganic & medicinal chemistry 2010;18(5):1761-72.
2010: Shan Jin; Yunfeng Cheng; Suazette Reid; Minyong Li; Binghe Wang
Carbohydrate recognition by boronolectins, small molecules, and lectins.
Medicinal research reviews 2010;30(2):171-257.
2010: Guojun Chen; Nanting Ni; Binghe Wang; Bingqian Xu
Fibrinogen nanofibril growth and self-assembly on Au (1,1,1) surface in the absence of thrombin.
Chemphyschem : a European journal of chemical physics and physical chemistry 2010;11(3):565-8.
2010: Xiaochuan Yang; Chaofeng Dai; Angie Dayan Calderon Molina; Binghe Wang
Boronic acid-modified DNA that changes fluorescent properties upon carbohydrate binding.
Chemical communications (Cambridge, England) 2010;46(7):1073-5.
2010: Shan Jin; Chunyuan Zhu; Yunfeng Cheng; Minyong Li; Binghe Wang
Synthesis and carbohydrate binding studies of fluorescent alpha-amidoboronic acids and the corresponding bisboronic acids.
Bioorganic & medicinal chemistry 2010;18(4):1449-55.
2010: Weixuan Chen; Ying-ju Huang; Sushma Reddy Gundala; Hsiuchin Yang; Minyong Li; Phang-Cheng Tai; Binghe Wang
The first low microM SecA inhibitors.
Bioorganic & medicinal chemistry 2010;18(4):1617-25.
2009: R D Harvey; J Nettles; Binghe Wang; S-Y Sun; Sagar Lonial
Commentary on Perrone et al.: 'vitamin C: not for breakfast anymore...if you have myeloma'.
Leukemia 2009;23(11):1939-40.
2009: Shan Jin; Gaurav Choudhary; Yunfeng Cheng; Chaofeng Dai; Minyong Li; Binghe Wang
Fluoride protects boronic acids in the copper(I)-mediated click reaction.
Chemical communications (Cambridge, England) 2009;(35):5251-3.
2009: Hanjing Peng; Yunfeng Cheng; Nanting Ni; Minyong Li; Gaurav Choudhary; Han Ting Chou; Chung-Dar Lu; Phang-Cheng Tai; Binghe Wang
Synthesis and evaluation of new antagonists of bacterial quorum sensing in Vibrio harveyi.
ChemMedChem 2009;4(9):1457-68.
2009: Nanting Ni; Gaurav Choudhary; Hanjing Peng; Minyong Li; Han-Ting Chou; Chung-Dar Lu; Eric S Gilbert; Binghe Wang
Inhibition of quorum sensing in Vibrio harveyi by boronic acids.
Chemical biology & drug design 2009;74(1):51-6.
2009: Kanghui Yang; Qiang Wang; Li Su; Hao Fang; Xuejian Wang; Jianzhi Gong; Binghe Wang; Wenfang Xu
Design and synthesis of novel chloramphenicol amine derivatives as potent aminopeptidase N (APN/CD13) inhibitors.
Bioorganic & medicinal chemistry 2009;17(11):3810-7.
2009: Nanting Ni; Gaurav Choudhary; Minyong Li; Binghe Wang
A new phenothiazine structural scaffold as inhibitors of bacterial quorum sensing in Vibrio harveyi.
Biochemical and biophysical research communications 2009;382(1):153-6.
2009: Luqing Shang; Hao Fang; Huawei Zhu; Xuejian Wang; Qiang Wang; Jiajia Mu; Binghe Wang; Shiroh Kishioka; Wenfang Xu
Design, synthesis and SAR studies of tripeptide analogs with the scaffold 3-phenylpropane-1,2-diamine as aminopeptidase N/CD13 inhibitors.
Bioorganic & medicinal chemistry 2009;17(7):2775-84.
2009: Shan Jin; Chunyuan Zhu; Minyong Li; Binghe Wang
Identification of the first fluorescent alpha-amidoboronic acids that change fluorescent properties upon sugar binding.
Bioorganic & medicinal chemistry letters 2009;19(6):1596-9.
2009: Michiya Kamio; Ko-Chun Ko; Shilong Zheng; Binghe Wang; Stacy L Collins; giovanni gadda; Phang-Cheng Tai; Charles D Derby
The chemistry of escapin: identification and quantification of the components in the complex mixture generated by an L-amino acid oxidase in the defensive secretion of the sea snail Aplysia californica.
Chemistry (Weinheim an der Bergstrasse, Germany) 2009;15(7):1597-603.
2009: Nanting Ni; Minyong Li; Junfeng Wang; Binghe Wang
Inhibitors and antagonists of bacterial quorum sensing.
Medicinal research reviews 2009;29(1):65-124.
2008: Shilong Zheng; Gurpreet Kaur; Huanchen Wang; Minyong Li; Megan Macnaughtan; Xiaochuan Yang; Suazette Reid; James H Prestegard; Binghe Wang; Hengming Ke
Design, synthesis, and structure-activity relationship, molecular modeling, and NMR studies of a series of phenyl alkyl ketones as highly potent and selective phosphodiesterase-4 inhibitors.
Journal of medicinal chemistry 2008;51(24):7673-88.
2008: Luqing Shang; Qiang Wang; Hao Fang; Jiajia Mu; Xuejian Wang; Yumei Yuan; Binghe Wang; Wenfang Xu
Novel 3-phenylpropane-1,2-diamine derivates as inhibitors of aminopeptidase N (APN).
Bioorganic & medicinal chemistry 2008;16(23):9984-90.
2008: Ko-Chun Ko; Binghe Wang; Phang-Cheng Tai; Charles D Derby
Identification of potent bactericidal compounds produced by escapin, an L-amino acid oxidase in the ink of the sea hare Aplysia californica.
Antimicrobial agents and chemotherapy 2008;52(12):4455-62.
2008: Minyong Li; Hao Fang; Lupei Du; Lin Xia; Binghe Wang
Computational studies of the binding site of alpha1A-adrenoceptor antagonists.
Journal of molecular modeling 2008;14(10):957-66.
2008: Minyong Li; Na Lin; Zhen Huang; Lupei Du; Craig Altier; Hao Fang; Binghe Wang
Selecting aptamers for a glycoprotein through the incorporation of the boronic acid moiety.
Journal of the American Chemical Society 2008;130(38):12636-8.
2008: Minyong Li; Nanting Ni; Han-Ting Chou; Chung-Dar Lu; Phang-Cheng Tai; Binghe Wang
Structure-based discovery and experimental verification of novel AI-2 quorum sensing inhibitors against Vibrio harveyi.
ChemMedChem 2008;3(8):1242-9.
2008: Shan Jin; Minyong Li; Chunyuan Zhu; ViLinh Tran; Binghe Wang
Computer-based de novo design, synthesis, and evaluation of boronic acid-based artificial receptors for selective recognition of dopamine.
Chembiochem : a European journal of chemical biology 2008;9(9):1431-8.
2008: Keng-Chang Tsai; Sheng-Hung Wang; Nai-Wan Hsiao; Minyong Li; Binghe Wang
The effect of different electrostatic potentials on docking accuracy: a case study using DOCK5.4.
Bioorganic & medicinal chemistry letters 2008;18(12):3509-12.
2008: Minyong Li; Nanting Ni; Binghe Wang; Yanqing Zhang
Modeling the excitation wavelengths (lambda(ex)) of boronic acids.
Journal of molecular modeling 2008;14(6):441-9.
2008: Qiang Wang; Maoying Chen; Huawei Zhu; Jie Zhang; Hao Fang; Binghe Wang; Wenfang Xu
Design, synthesis, and QSAR studies of novel lysine derives as amino-peptidase N/CD13 inhibitors.
Bioorganic & medicinal chemistry 2008;16(10):5473-81.
2008: Nanting Ni; Han-Ting Chou; Junfeng Wang; Minyong Li; Chung-Dar Lu; Phang-Cheng Tai; Binghe Wang
Identification of boronic acids as antagonists of bacterial quorum sensing in Vibrio harveyi.
Biochemical and biophysical research communications 2008;369(2):590-4.
2008: Minyong Li; Ying-Ju Huang; Phang-Cheng Tai; Binghe Wang
Discovery of the first SecA inhibitors using structure-based virtual screening.
Biochemical and biophysical research communications 2008;368(4):839-45.
2008: Nanting Ni; Gaurav Choudhary; Minyong Li; Binghe Wang
Pyrogallol and its analogs can antagonize bacterial quorum sensing in Vibrio harveyi.
Bioorganic & medicinal chemistry letters 2008;18(5):1567-72.
2008: M Li; Binghe Wang; W Lin
Cl-channel blockers inhibit cell proliferation and arrest the cell cycle of human ovarian cancer cells.
European journal of gynaecological oncology 2008;29(3):267-71.
2008: Shan Jin; Junfeng Wang; Minyong Li; Binghe Wang
Synthesis, evaluation, and computational studies of naphthalimide-based long-wavelength fluorescent boronic Acid reporters.
Chemistry (Weinheim an der Bergstrasse, Germany) 2008;14(9):2795-804.
2007: Minyong Li; Binghe Wang
Homology modeling and examination of the effect of the D92E mutation on the H5N1 nonstructural protein NS1 effector domain.
Journal of molecular modeling 2007;13(12):1237-44.
2007: Senol Akay; Wenqian Yang; Junfeng Wang; Li Lin; Binghe Wang
Synthesis and evaluation of dual wavelength fluorescent benzo[b]thiophene boronic acid derivatives for sugar sensing.
Chemical biology & drug design 2007;70(4):279-89.
2007: Yanling Zhang; C Eric Ballard; Shi-Long Zheng; Xingming Gao; Ko-Chun Ko; Hsiuchin Yang; Gary Brandt; Xinhui Lou; Phang-Cheng Tai; Chung-Dar Lu; Binghe Wang
Design, synthesis, and evaluation of efflux substrate-metal chelator conjugates as potential antimicrobial agents.
Bioorganic & medicinal chemistry letters 2007;17(3):707-11.
2007: Bo Jin; Yan-Qing Zhang; Binghe Wang
Granular kernel trees with parallel genetic algorithms for drug activity comparisons.
International journal of data mining and bioinformatics 2007;1(3):270-85.
2007: Na Lin; Jun Yan; Zhen Huang; Craig Altier; Minyong Li; Nicolas Carrasco; Mitsu Suyemoto; Lynette Johnston; Siming Wang; Qian Wang; Hao Fang; Julianne Caton-Williams; Binghe Wang
Design and synthesis of boronic-acid-labeled thymidine triphosphate for incorporation into DNA.
Nucleic acids research 2007;35(4):1222-9.
2006: Minyong Li; Binghe Wang
Computational studies of H5N1 hemagglutinin binding with SA-alpha-2, 3-Gal and SA-alpha-2, 6-Gal.
Biochemical and biophysical research communications 2006;347(3):662-8.
2006: Junfeng Wang; Shan Jin; Na Lin; Binghe Wang
Fluorescent indolylboronic acids that are useful reporters for the synthesis of boronolectins.
Chemical biology & drug design 2006;67(2):137-44.
2006: Yanling Zhang; Xingming Gao; Kenneth Hardcastle; Binghe Wang
Water-soluble fluorescent boronic acid compounds for saccharide sensing: substituent effects on their fluorescence properties.
Chemistry (Weinheim an der Bergstrasse, Germany) 2006;12(5):1377-84.
2006: Wei Zou; Ping Yue; Na Lin; Min He; Zhongmei Zhou; Sagar Lonial; Fadlo R Khuri; Binghe Wang; Shi-Yong Sun
Vitamin C inactivates the proteasome inhibitor PS-341 in human cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(1):273-80.
2005: Jun Yan; Hao Fang; Binghe Wang
Boronolectins and fluorescent boronolectins: an examination of the detailed chemistry issues important for the design.
Medicinal research reviews 2005;25(5):490-520.
2005: Hideaki Watanabe; Adam J Mamelak; Elliot Weiss; Binghe Wang; Irwin Freed; Angela K Brice; Lynn M Wachtman; Kathleen L Gabrielson; Naoko Yokota; Daniel J Hicklin; Robert S Kerbel; Mark Haas; Daniel N Sauder
Anti-vascular endothelial growth factor receptor-2 antibody accelerates renal disease in the NZB/W F1 murine systemic lupus erythematosus model.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(1):407-9.
2004: Weijuan Ni; Gurpreet Kaur; Greg Springsteen; Binghe Wang; Stefan Franzen
Regulating the fluorescence intensity of an anthracene boronic acid system: a B-N bond or a hydrolysis mechanism?
Bioorganic chemistry 2004;32(6):571-81.
2004: Hao Fang; Gurpreet Kaur; Binghe Wang
Progress in boronic acid-based fluorescent glucose sensors.
Journal of fluorescence 2004;14(5):481-9.
2004: Wenqian Yang; Haiying Fan; Xingming Gao; Shouhai Gao; Vishnu Vardhan Reddy Karnati; Weijuan Ni; W Borden Hooks; John Carson; Brent W Weston; Binghe Wang
The first fluorescent diboronic acid sensor specific for hepatocellular carcinoma cells expressing sialyl Lewis X.
Chemistry & biology 2004;11(4):439-48.
2004: Lindsay A Zych; Wenqian Yang; Yuan Liao; Kellee R Griffin; Binghe Wang
The effect of substitution patterns on the release rates of opioid peptides DADLE and [Leu(5)]-enkephalin from coumarin prodrug moieties.
Bioorganic chemistry 2004;32(2):109-23.
2004: Weijuan Ni; Hao Fang; Greg Springsteen; Binghe Wang
The design of boronic acid spectroscopic reporter compounds by taking advantage of the pK(a)-lowering effect of diol binding: nitrophenol-based color reporters for diols.
The Journal of organic chemistry 2004;69(6):1999-2007.
2004: Hao Fang; Jun Yan; Binghe Wang
Biaryl product formation from cross-coupling in palladium-catalyzed borylation of a Boc protected aminobromoquinoline compound.
Molecules (Basel, Switzerland) 2004;9(3):178-84.
2003: Xingming Gao; Yanling Zhang; Binghe Wang
New boronic acid fluorescent reporter compounds. 2. A naphthalene-based on-off sensor functional at physiological pH.
Organic letters 2003;5(24):4615-8.
2003: Hashmat A Sikder; David L Huso; Hong Zhang; Binghe Wang; Byungwoo Ryu; Sam T Hwang; Jonathan D Powell; Rhoda M Alani
Disruption of Id1 reveals major differences in angiogenesis between transplanted and autochthonous tumors.
Cancer cell 2003;4(4):291-9.
2003: Wenqian Yang; Xingming Gao; Binghe Wang
Boronic acid compounds as potential pharmaceutical agents.
Medicinal research reviews 2003;23(3):346-68.
2003: Wenqian Yang; Jun Yan; Greg Springsteen; Susan Deeter; Binghe Wang
A novel type of fluorescent boronic acid that shows large fluorescence intensity changes upon binding with a carbohydrate in aqueous solution at physiological pH.
Bioorganic & medicinal chemistry letters 2003;13(6):1019-22.
2003: Wenqian Yang; Jun Yan; Hao Fang; Binghe Wang
The first fluorescent sensor for D-glucarate based on the cooperative action of boronic acid and guanidinium groups.
Chemical communications (Cambridge, England) 2003;(6):792-3.
2002: Vishnu Vardhan Reddy Karnati; Xingming Gao; Shouhai Gao; Wenqian Yang; Weijuan Ni; Sabapathy Sankar; Binghe Wang
A glucose-selective fluorescence sensor based on boronic acid-diol recognition.
Bioorganic & medicinal chemistry letters 2002;12(23):3373-7.
2002: Wenqian Yang; Shouhai Gao; Xingming Gao; Vishnu Vardhan Reddy Karnati; Weijuan Ni; Binghe Wang; W Borden Hooks; John Carson; Brent W Weston
Diboronic acids as fluorescent probes for cells expressing sialyl Lewis X.
Bioorganic & medicinal chemistry letters 2002;12(16):2175-7.
2002: CE Ballard; H Yu; Binghe Wang
Recent developments in depsipeptide research.
Current medicinal chemistry 2002;9(4):471-98.
2001: J Jiang; W Wang; D C Sane; Binghe Wang
Synthesis of RGD analogs as potential vectors for targeted drug delivery.
Bioorganic chemistry 2001;29(6):357-79.
2001: Shouhai Gao; W Wang; Binghe Wang
Building fluorescent sensors for carbohydrates using template-directed polymerizations.
Bioorganic chemistry 2001;29(5):308-20.
2001: Greg Springsteen; CE Ballard; Shouhai Gao; W Wang; Binghe Wang
The development of photometric sensors for boronic acids.
Bioorganic chemistry 2001;29(5):259-70.
2001: Greg Springsteen; Binghe Wang
Alizarin Red S. as a general optical reporter for studying the binding of boronic acids with carbohydrates.
Chemical communications (Cambridge, England) 2001;(17):1608-9.
2000: Yuan Liao; S Hendrata; S Y Bae; Binghe Wang
The effect of phenyl substituents on the release rates of esterase-sensitive coumarin-based prodrugs.
Chemical & pharmaceutical bulletin 2000;48(8):1138-47.
2000: W Wang; R T Borchardt; Binghe Wang
Orally active peptidomimetic RGD analogs that are glycoprotein IIb/IIIa antagonists.
Current medicinal chemistry 2000;7(4):437-53.
2000: W Wang; G Camenisch; D C Sane; H Zhang; E Hugger; G L Wheeler; Ronald T Borchardt; Binghe Wang
A coumarin-based prodrug strategy to improve the oral absorption of RGD peptidomimetics.
Journal of controlled release : official journal of the Controlled Release Society 2000;65(1-2):245-51.
2000: D Shan; A Zheng; CE Ballard; W Wang; Ronald T Borchardt; Binghe Wang
A facilitated cyclic ether formation and its potential application in solid-phase peptide and organic synthesis.
Chemical & pharmaceutical bulletin 2000;48(2):238-44.
1999: W Wang; S Gao; Binghe Wang
Building fluorescent sensors by template polymerization: the preparation of a fluorescent sensor for D-fructose.
Organic letters 1999;1(8):1209-12.
1999: Yuan Liao; Binghe Wang
Substituted coumarins as esterase-sensitive prodrug moieties with improved release rates.
Bioorganic & medicinal chemistry letters 1999;9(13):1795-800.
1999: OS Gudmundsson; Seetharama D S Jois; David VanderVelde; Teruna J Siahaan; Binghe Wang; Ronald T Borchardt
The effect of conformation on the membrane permeation of coumarinic acid- and phenylpropionic acid-based cyclic prodrugs of opioid peptides.
The journal of peptide research : official journal of the American Peptide Society 1999;53(4):383-92.
1999: Binghe Wang; K Nimkar; W Wang; H Zhang; D Shan; OS Gudmundsson; S Gangwar; Teruna J Siahaan; Ronald T Borchardt
Synthesis and evaluation of the physicochemical properties of esterase-sensitive cyclic prodrugs of opioid peptides using coumarinic acid and phenylpropionic acid linkers.
The journal of peptide research : official journal of the American Peptide Society 1999;53(4):370-82.
1999: W Wang; J Jiang; CE Ballard; Binghe Wang
Prodrug approaches to the improved delivery of peptide drugs.
Current pharmaceutical design 1999;5(4):265-87.
1999: Binghe Wang; D Shan; W Wang; H Zhang; OS Gudmundsson; Ronald T Borchardt
Synthesis of coumarin-based, esterase-sensitive cyclic prodrugs of opioid peptides with enhanced membrane permeability and enzymatic stability.
Methods in molecular medicine 1999;23():71-85.
1999: Binghe Wang; S Gangwar; GM Pauletti; Teruna J Siahaan; Ronald T Borchardt
Synthesis of an esterase-sensitive cyclic prodrug of a model hexapeptide having enhanced membrane permeability and enzymatic stability using a 3-(2'-hydroxy-4',6'-dimethylphenyl)-3,3-dimethyl propionic Acid promoiety.
Methods in molecular medicine 1999;23():53-69.
1999: Binghe Wang; W Wang; G P Camenisch; J Elmo; H Zhang; Ronald T Borchardt
Synthesis and evaluation of novel coumarin-based esterase-sensitive cyclic prodrugs of peptidomimetic RGD analogs with improved membrane permeability.
Chemical & pharmaceutical bulletin 1999;47(1):90-5.
1999: OS Gudmundsson; GM Pauletti; W Wang; D Shan; H Zhang; Binghe Wang; Ronald T Borchardt
Coumarinic acid-based cyclic prodrugs of opioid peptides that exhibit metabolic stability to peptidases and excellent cellular permeability.
Pharmaceutical research 1999;16(1):7-15.
1998: G P Camenisch; W Wang; Binghe Wang; Ronald T Borchardt
A comparison of the bioconversion rates and the Caco-2 cell permeation characteristics of coumarin-based cyclic prodrugs and methylester-based linear prodrugs of RGD peptidomimetics.
Pharmaceutical research 1998;15(8):1174-81.
1998: Binghe Wang; H Zhang; A Zheng; W Wang
Coumarin-based prodrugs. Part 3: Structural effects on the release kinetics of esterase-sensitive prodrugs of amines.
Bioorganic & medicinal chemistry 1998;6(4):417-26.
1997: D Shan; M G Nicolaou; Ronald T Borchardt; Binghe Wang
Prodrug strategies based on intramolecular cyclization reactions.
Journal of pharmaceutical sciences 1997;86(7):765-7.
1997: GM Pauletti; S Gangwar; Binghe Wang; Ronald T Borchardt
Esterase-sensitive cyclic prodrugs of peptides: evaluation of a phenylpropionic acid promoiety in a model hexapeptide.
Pharmaceutical research 1997;14(1):11-7.
1993: Binghe Wang; Fusao Takusagawa; M P Mertes; K Bowman-James
Structure of the product from a novel cyclization reaction involving a C(6)-substituted uridine analog.
Acta crystallographica. Section C, Crystal structure communications 1993;49 ( Pt 9)():1568-71.