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Baikun Wang

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Chemicals & Drugs

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Sunil S Metkar; Julian Pardo; Baikun Wang; Gregor Anderluh; Elena Catalan; Robert J C Gilbert; Christopher J Froelich
Perforin rapidly induces plasma membrane phospholipid flip-flop.
Sunil S Metkar; Cheikh Menaa; Julian Pardo; Baikun Wang; Reinhard Wallich; Marina Freudenberg; Stephen Kim; Srikumar M Raja; Lianfa Shi; Markus M Simon; Christopher J Froelich
Human and mouse granzyme A induce a proinflammatory cytokine response.
Srikumar M Raja; Sunil S Metkar; Stefan Höning; Baikun Wang; William A Russin; Nina H Pipalia; Cheikh Menaa; Mattias Belting; Xuefang Cao; Ralf Dressel; Christopher J Froelich
A novel mechanism for protein delivery: granzyme B undergoes electrostatic exchange from serglycin to target cells.

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All Publications

2011: Sunil S Metkar; Julian Pardo; Baikun Wang; Gregor Anderluh; Elena Catalan; Robert J C Gilbert; Christopher J Froelich
Perforin rapidly induces plasma membrane phospholipid flip-flop.
PloS one 2011;6(9):e24286.
2008: Sunil S Metkar; Cheikh Menaa; Julian Pardo; Baikun Wang; Reinhard Wallich; Marina Freudenberg; Stephen Kim; Srikumar M Raja; Lianfa Shi; Markus M Simon; Christopher J Froelich
Human and mouse granzyme A induce a proinflammatory cytokine response.
Immunity 2008;29(5):720-33.
2005: Srikumar M Raja; Sunil S Metkar; Stefan Höning; Baikun Wang; William A Russin; Nina H Pipalia; Cheikh Menaa; Mattias Belting; Xuefang Cao; Ralf Dressel; Christopher J Froelich
A novel mechanism for protein delivery: granzyme B undergoes electrostatic exchange from serglycin to target cells.
The Journal of biological chemistry 2005;280(21):20752-61.
2005: Sunil S Metkar; Baikun Wang; Christopher J Froelich
Detection of functional cell surface perforin by flow cytometry.
Journal of immunological methods 2005;299(1-2):117-27.
2003: Carl E Mackewicz; Baikun Wang; Sunil S Metkar; Matthew Richey; Christopher J Froelich; Jay A Levy
Lack of the CD8+ cell anti-HIV factor in CD8+ cell granules.
Blood 2003;102(1):180-3.
2003: Sunil S Metkar; Baikun Wang; Michelle L Ebbs; Jin H Kim; Yong J Lee; Srikumar M Raja; Christopher J Froelich
Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis.
The Journal of cell biology 2003;160(6):875-85.
2002: Srikumar M Raja; Baikun Wang; Mandakini Dantuluri; Umesh R Desai; Borries Demeler; Katharina Spiegel; Sunil S Metkar; Christopher J Froelich
Cytotoxic cell granule-mediated apoptosis. Characterization of the macromolecular complex of granzyme B with serglycin.
The Journal of biological chemistry 2002;277(51):49523-30.
2002: Sunil S Metkar; Baikun Wang; Miguel Aguilar-Santelises; Srikumar M Raja; Lars Uhlin-Hansen; Eckhard R Podack; Joseph A Trapani; Christopher J Froelich
Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation.
Immunity 2002;16(3):417-28.
2001: Sunil S Metkar; Miguel Aguilar-Santelises; Baikun Wang; Christopher J Froelich
Flow cytometry cannot assess surface binding of perforin to target cells.
Blood 2001;97(7):2181-3.
1999: John Galvin; L H Spaeny-Dekking; Baikun Wang; Prem Seth; C E Hack; Christopher J Froelich
Apoptosis induced by granzyme B-glycosaminoglycan complexes: implications for granule-mediated apoptosis in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(9):5345-50.
1998: X Yang; Henning Stennicke; Baikun Wang; Douglas R Green; R U Jänicke; A Srinivasan; Prem Seth; Guy S Salvesen; Christopher J Froelich
Granzyme B mimics apical caspases. Description of a unified pathway for trans-activation of executioner caspase-3 and -7.
The Journal of biological chemistry 1998;273(51):34278-83.