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Dingzhi Wang

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TOP 3
Dingzhi Wang; Ofer Margalit; Raymond N DuBois
Metronomic topotecan for colorectal cancer: a promising new option.
Dingzhi Wang; Raymond N DuBois
The role of anti-inflammatory drugs in colorectal cancer.
Ofer Margalit; Dingzhi Wang; Raymond N Dubois
PPARγ agonists target aromatase via both PGE2 and BRCA1.

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All Publications

2013: Dingzhi Wang; Ofer Margalit; Raymond N DuBois
Metronomic topotecan for colorectal cancer: a promising new option.
Gut 2013;62(2):190-1.
2013: Dingzhi Wang; Raymond N DuBois
The role of anti-inflammatory drugs in colorectal cancer.
Annual review of medicine 2013;64():131-44.
2012: Ofer Margalit; Dingzhi Wang; Raymond N Dubois
PPARγ agonists target aromatase via both PGE2 and BRCA1.
Cancer prevention research (Philadelphia, Pa.) 2012;5(10):1169-72.
2012: Moubin Lin; Dingzhi Wang; George A Calin; Raymond N Dubois; Lee M Ellis; Cathy Eng; Jian Gu; Ernest T Hawk; Michelle A Hildebrandt; Maosheng Huang; Jie Lin; Xifeng Wu
Genetic polymorphisms in MicroRNA-related genes as predictors of clinical outcomes in colorectal adenocarcinoma patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(14):3982-91.
2012: Dingzhi Wang; Raymond N DuBois
The role of the PGE2-aromatase pathway in obesity-associated breast inflammation.
Cancer discovery 2012;2(4):308-10.
2012: Dingzhi Wang; Raymond N Dubois
Associations between obesity and cancer: the role of fatty acid synthase.
Journal of the National Cancer Institute 2012;104(5):343-5.
2012: Dingzhi Wang; D Xie; L Guo; W Ning; Raymond DuBois
Peroxisome proliferator-activated receptor δ confers resistance to peroxisome proliferator-activated receptor γ-induced apoptosis in colorectal cancer cells.
Oncogene 2012;31(8):1013-23.
2012: Dianren Xia; Hiroshi Katoh; Sun-Hee Kim; Dingzhi Wang; Raymond N DuBois
Prostaglandin E2 promotes intestinal tumor growth via DNA methylation.
Nature medicine 2012;18(2):224-6.
2011: Toni A Nagy; Jennifer Noto; Seth R Ogden; Pelayo Correa; Timothy L Cover; Alberto Delgado; Dawn A Israel; M Blanca Piazuelo; Judith Romero-Gallo; Dingzhi Wang; Lydia E Wroblewski; Richard M Peek
β-Catenin and p120 mediate PPARδ-dependent proliferation induced by Helicobacter pylori in human and rodent epithelia.
Gastroenterology 2011;141(2):553-64.
2010: Dingzhi Wang; Raymond N DuBois
Therapeutic potential of peroxisome proliferator-activated receptors in chronic inflammation and colorectal cancer.
Gastroenterology clinics of North America 2010;39(3):697-707.
2010: Dingzhi Wang; Raymond DuBois
Eicosanoids and cancer.
Nature reviews. Cancer 2010;10(3):181-93.
2010: Dingzhi Wang; Raymond DuBois
The role of COX-2 in intestinal inflammation and colorectal cancer.
Oncogene 2010;29(6):781-8.
2010: Dianren Xia; Vijaykumar R Holla; Dingzhi Wang; David G Menter; Raymond DuBois
HEF1 is a crucial mediator of the proliferative effects of prostaglandin E(2) on colon cancer cells.
Cancer research 2010;70(2):824-31.
2010: Vijay G Peddareddigari; Dingzhi Wang; Raymond N Dubois
The tumor microenvironment in colorectal carcinogenesis.
Cancer microenvironment : official journal of the International Cancer Microenvironment Society 2010;3(1):149-66.
2009: Dingzhi Wang; Raymond DuBois; Ann Richmond
The role of chemokines in intestinal inflammation and cancer.
Current opinion in pharmacology 2009;9(6):688-96.
2008: Tetyana V Pedchenko; Adriana L Gonzalez; Dingzhi Wang; Raymond DuBois; Pierre P Massion
Peroxisome proliferator-activated receptor beta/delta expression and activation in lung cancer.
American journal of respiratory cell and molecular biology 2008;39(6):689-96.
2008: Dingzhi Wang; Raymond DuBois
Pro-inflammatory prostaglandins and progression of colorectal cancer.
Cancer letters 2008;267(2):197-203.
2008: Dingzhi Wang; Haibin Wang; Wei Ning; Michael G Backlund; Sudhansu K Dey; Raymond DuBois
Loss of cannabinoid receptor 1 accelerates intestinal tumor growth.
Cancer research 2008;68(15):6468-76.
2008: Dingzhi Wang; Raymond DuBois
Peroxisome proliferator-activated receptors and progression of colorectal cancer.
PPAR research 2008;2008():931074.
2007: Haibin Wang; Huirong Xie; Xiaofei Sun; Susanne Tranguch; Hao Zhang; Xiangxu Jia; Dingzhi Wang; Sanjoy K Das; Béatrice Desvergne; Walter Wahli; Raymond DuBois; Sudhansu K Dey
Stage-specific integration of maternal and embryonic peroxisome proliferator-activated receptor delta signaling is critical to pregnancy success.
The Journal of biological chemistry 2007;282(52):37770-82.
2007: Takiko Daikoku; Susanne Tranguch; Anindita Chakrabarty; Dingzhi Wang; Dineo Khabele; Sandra Orsulic; Jason D Morrow; Raymond DuBois; Sudhansu K Dey
Extracellular signal-regulated kinase is a target of cyclooxygenase-1-peroxisome proliferator-activated receptor-delta signaling in epithelial ovarian cancer.
Cancer research 2007;67(11):5285-92.
2007: Dingzhi Wang; Raymond DuBois
Inflammatory mediators and nuclear receptor signaling in colorectal cancer.
Cell cycle (Georgetown, Tex.) 2007;6(6):682-5.
2007: Dingzhi Wang; Raymond DuBois
Measurement of eicosanoids in cancer tissues.
Methods in enzymology 2007;433():27-50.
2006: Dingzhi Wang; Haibin Wang; Yong Guo; Wei Ning; Sharada Katkuri; Walter Wahli; Béatrice Desvergne; Sudhansu K Dey; Raymond DuBois
Crosstalk between peroxisome proliferator-activated receptor delta and VEGF stimulates cancer progression.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(50):19069-74.
2006: Dingzhi Wang; Haibin Wang; Joanne Brown; Takiko Daikoku; Wei Ning; Qiong Shi; Ann Richmond; Robert M Strieter; Sudhansu K Dey; Raymond DuBois
CXCL1 induced by prostaglandin E2 promotes angiogenesis in colorectal cancer.
The Journal of experimental medicine 2006;203(4):941-51.
2006: Michael G Backlund; Jason R Mann; Dingzhi Wang; Raymond DuBois
Ras up-regulation of cyclooxygenase-2.
Methods in enzymology 2006;407():401-10.
2005: Erik S Musiek; Ling Gao; Ginger L Milne; Wei Han; M Brett Everhart; Dingzhi Wang; Michael G Backlund; Raymond DuBois; Giuseppe Zanoni; Giovanni Vidari; Timothy S Blackwell; Jason D Morrow
Cyclopentenone isoprostanes inhibit the inflammatory response in macrophages.
The Journal of biological chemistry 2005;280(42):35562-70.
2005: Dingzhi Wang; Jason R Mann; Raymond DuBois
The role of prostaglandins and other eicosanoids in the gastrointestinal tract.
Gastroenterology 2005;128(5):1445-61.
2005: Takiko Daikoku; Dingzhi Wang; Susanne Tranguch; Jason D Morrow; Sandra Orsulic; Raymond DuBois; Sudhansu K Dey
Cyclooxygenase-1 is a potential target for prevention and treatment of ovarian epithelial cancer.
Cancer research 2005;65(9):3735-44.
2005: Dingzhi Wang; F Gregory Buchanan; Haibin Wang; Sudhansu K Dey; Raymond DuBois
Prostaglandin E2 enhances intestinal adenoma growth via activation of the Ras-mitogen-activated protein kinase cascade.
Cancer research 2005;65(5):1822-9.
2005: Vijaykumar R Holla; Dingzhi Wang; Joanne R Brown; Jason R Mann; Sharada Katkuri; Raymond DuBois
Prostaglandin E2 regulates the complement inhibitor CD55/decay-accelerating factor in colorectal cancer.
The Journal of biological chemistry 2005;280(1):476-83.
2004: Dingzhi Wang; Jason R Mann; Raymond DuBois
WNT and cyclooxygenase-2 cross-talk accelerates adenoma growth.
Cell cycle (Georgetown, Tex.) 2004;3(12):1512-5.
2004: Jiqing Sai; Guo-Huang Fan; Dingzhi Wang; Ann Richmond
The C-terminal domain LLKIL motif of CXCR2 is required for ligand-mediated polarization of early signals during chemotaxis.
Journal of cell science 2004;117(Pt 23):5489-96.
2004: Haibin Wang; Yong Guo; Dingzhi Wang; Philip J Kingsley; Lawrence J Marnett; Sanjoy K Das; Raymond DuBois; Sudhansu K Dey
Aberrant cannabinoid signaling impairs oviductal transport of embryos.
Nature medicine 2004;10(10):1074-80.
2004: Dingzhi Wang; Haibin Wang; Qiong Shi; Sharada Katkuri; Walter Walhi; Béatrice Desvergne; Sanjoy K Das; Sudhansu K Dey; Raymond DuBois
Prostaglandin E(2) promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor delta.
Cancer cell 2004;6(3):285-95.
2004: Rajnish A Gupta; Dingzhi Wang; Sharada Katkuri; Haibin Wang; Sudhansu K Dey; Raymond DuBois
Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth.
Nature medicine 2004;10(3):245-7.
2004: Dingzhi Wang; Raymond DuBois
Cyclooxygenase-2: a potential target in breast cancer.
Seminars in oncology 2004;31(1 Suppl 3):64-73.
2004: Dingzhi Wang; Raymond DuBois
Cyclooxygenase 2-derived prostaglandin E2 regulates the angiogenic switch.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(2):415-6.
2003: F Gregory Buchanan; Dingzhi Wang; Francesca Bargiacchi; Raymond DuBois
Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor.
The Journal of biological chemistry 2003;278(37):35451-7.
2003: Dingzhi Wang; Jiqing Sai; Ann Richmond
Cell surface heparan sulfate participates in CXCL1-induced signaling.
Biochemistry 2003;42(4):1071-7.
2002: Dingzhi Wang; Jiqing Sai; Glendora Carter; Aristidis Sachpatzidis; Elias Lolis; Ann Richmond
PAK1 kinase is required for CXCL1-induced chemotaxis.
Biochemistry 2002;41(22):7100-7.
2001: Dingzhi Wang; Ann Richmond
Nuclear factor-kappa B activation by the CXC chemokine melanoma growth-stimulatory activity/growth-regulated protein involves the MEKK1/p38 mitogen-activated protein kinase pathway.
The Journal of biological chemistry 2001;276(5):3650-9.
2000: Dingzhi Wang; W Yang; Jianguo Du; MN Devalaraja; P Liang; K Matsumoto; K Tsubakimoto; T Endo; Ann Richmond
MGSA/GRO-mediated melanocyte transformation involves induction of Ras expression.
Oncogene 2000;19(40):4647-59.
2000: H Haghnegahdar; Jianguo Du; Dingzhi Wang; Robert M Strieter; M D Burdick; Lillian B Nanney; Nancy L Cardwell; Jing Luan; RL Shattuck-Brandt; Ann Richmond
The tumorigenic and angiogenic effects of MGSA/GRO proteins in melanoma.
Journal of leukocyte biology 2000;67(1):53-62.
1999: W Yang; Dingzhi Wang; Ann Richmond
Role of clathrin-mediated endocytosis in CXCR2 sequestration, resensitization, and signal transduction.
The Journal of biological chemistry 1999;274(16):11328-33.
1997: Dingzhi Wang; Jose Zamorano; Achsah D Keegan; Mark Boothby
HMG-I(Y) phosphorylation status as a nuclear target regulated through insulin receptor substrate-1 and the I4R motif of the interleukin-4 receptor.
The Journal of biological chemistry 1997;272(40):25083-90.