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John Brady

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TOP 3
Sébastien A Chevalier; Andrea Cimarelli; Arindam Dasgupta; Stéphanie Durand; Renaud Mahieux; John N Brady; Michael F Radonovich; Cynthia A Pise-Masison
The transcription profile of Tax-3 is more similar to Tax-1 than Tax-2: insights into HTLV-3 potential leukemogenic properties.
Dustin C Edwards; Claudio Fenizia; Kyung-Jin Jung; Katherine M McKinnon; John N Brady; Cynthia A Pise-Masison
Inhibition of geranylgeranyl transferase-I decreases cell viability of HTLV-1-transformed cells.
Won-Kyung Cho; Moon Kyoo Jang; Keven Huang; Cynthia A Pise-Masison; John N Brady
Human T-lymphotropic virus type 1 Tax protein complexes with P-TEFb and competes for Brd4 and 7SK snRNP/HEXIM1 binding.

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All Publications

2012: Sébastien A Chevalier; Andrea Cimarelli; Arindam Dasgupta; Stéphanie Durand; Renaud Mahieux; John N Brady; Michael F Radonovich; Cynthia A Pise-Masison
The transcription profile of Tax-3 is more similar to Tax-1 than Tax-2: insights into HTLV-3 potential leukemogenic properties.
PloS one 2012;7(7):e41003.
2011: Dustin C Edwards; Claudio Fenizia; Kyung-Jin Jung; Katherine M McKinnon; John N Brady; Cynthia A Pise-Masison
Inhibition of geranylgeranyl transferase-I decreases cell viability of HTLV-1-transformed cells.
Viruses 2011;3(10):1815-35.
2010: Won-Kyung Cho; Moon Kyoo Jang; Keven Huang; Cynthia A Pise-Masison; John N Brady
Human T-lymphotropic virus type 1 Tax protein complexes with P-TEFb and competes for Brd4 and 7SK snRNP/HEXIM1 binding.
Journal of virology 2010;84(24):12801-9.
2010: Rebecca Easley; Lawrence Carpio; Irene Guendel; Zachary Klase; Soyun Choi; Kylene Kehn-Hall; John N Brady; Fatah Kashanchi
Human T-lymphotropic virus type 1 transcription and chromatin-remodeling complexes.
Journal of virology 2010;84(9):4755-68.
2009: Chloé Journo; Josina Filipe; Frédégonde About; Sébastien A Chevalier; Philippe V Afonso; John N Brady; David Flynn; Frédéric Tangy; Alain Israël; Pierre-Olivier Vidalain; Renaud Mahieux; Robert Weil
NRP/Optineurin Cooperates with TAX1BP1 to potentiate the activation of NF-kappaB by human T-lymphotropic virus type 1 tax protein.
PLoS pathogens 2009;5(7):e1000521.
2009: Cynthia A Pise-Masison; Michael F Radonovich; Kathleen Dohoney; John C Morris; Deirdre O'Mahony; Min-Jung Lee; Jane Trepel; Thomas Waldmann; John E Janik; John N Brady
Gene expression profiling of ATL patients: compilation of disease-related genes and evidence for TCF4 involvement in BIRC5 gene expression and cell viability.
Blood 2009;113(17):4016-26.
2009: Shuhei Sakakibara; Cynthia A Pise-Masison; John N Brady; Giovanna Tosato
Gene regulation and functional alterations induced by Kaposi's sarcoma-associated herpesvirus-encoded ORFK13/vFLIP in endothelial cells.
Journal of virology 2009;83(5):2140-53.
2009: Meisheng Zhou; Keven Huang; Kyung-Jin Jung; Won-Kyung Cho; Zach Klase; Fatah Kashanchi; Cynthia A Pise-Masison; John N Brady
Bromodomain protein Brd4 regulates human immunodeficiency virus transcription through phosphorylation of CDK9 at threonine 29.
Journal of virology 2009;83(2):1036-44.
2008: Kyung-Jin Jung; Arindam Dasgupta; Keven Huang; Soo-Jin Jeong; Cynthia A Pise-Masison; Katerina V Gurova; John N Brady
Small-molecule inhibitor which reactivates p53 in human T-cell leukemia virus type 1-transformed cells.
Journal of virology 2008;82(17):8537-47.
2008: Sébastien Alain Chevalier; Nga Ling Ko; Sara Calattini; Adeline Mallet; Marie-Christine Prévost; Kylene Kehn; John N Brady; Fatah Kashanchi; Antoine Gessain; Renaud Mahieux
Construction and characterization of a human T-cell lymphotropic virus type 3 infectious molecular clone.
Journal of virology 2008;82(13):6747-52.
2008: Anne Gegonne; Jocelyn D Weissman; Hanxin Lu; Meisheng Zhou; Arindam Dasgupta; Robert Ribble; John N Brady; dinah singer
TFIID component TAF7 functionally interacts with both TFIIH and P-TEFb.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(14):5367-72.
2008: Soo-Jin Jeong; Arindam Dasgupta; Kyung-Jin Jung; Jee-Hyun Um; Aileen Burke; Hyeon Ung Park; John N Brady
PI3K/AKT inhibition induces caspase-dependent apoptosis in HTLV-1-transformed cells.
Virology 2008;370(2):264-72.
2008: Arindam Dasgupta; Kyung-Jin Jung; Soo-Jin Jeong; John N Brady
Inhibition of methyltransferases results in induction of g2/m checkpoint and programmed cell death in human T-lymphotropic virus type 1-transformed cells.
Journal of virology 2008;82(1):49-59.
2007: Won-Kyung Cho; Meisheng Zhou; Moon Kyoo Jang; Keven Huang; Soo-Jin Jeong; Keiko Ozato; John N Brady
Modulation of the Brd4/P-TEFb interaction by the human T-lymphotropic virus type 1 tax protein.
Journal of virology 2007;81(20):11179-86.
2007: Francesca M Couto; Alexandra H Minn; Cynthia A Pise-Masison; Michael F Radonovich; John N Brady; Matthew Hanson; Luis A Fernandez; Ping Wang; Christina Kendziorski; Anath Shalev
Exenatide blocks JAK1-STAT1 in pancreatic beta cells.
Metabolism: clinical and experimental 2007;56(7):915-8.
2006: Soo-Jin Jeong; Hanxin Lu; Won-Kyung Cho; Hyeon Ung Park; Cynthia A Pise-Masison; John N Brady
Coactivator-associated arginine methyltransferase 1 enhances transcriptional activity of the human T-cell lymphotropic virus type 1 long terminal repeat through direct interaction with Tax.
Journal of virology 2006;80(20):10036-44.
2006: Sébastien Alain Chevalier; Laurent Meertens; Cynthia A Pise-Masison; Sara Calattini; H Park; A A Alhaj; M Zhou; Antoine Gessain; F Kashanchi; John N Brady; Renaud Mahieux
The tax protein from the primate T-cell lymphotropic virus type 3 is expressed in vivo and is functionally related to HTLV-1 Tax rather than HTLV-2 Tax.
Oncogene 2006;25(32):4470-82.
2006: Meisheng Zhou; Hanxin Lu; Hyeon Park; Jaime Wilson-Chiru; Rebecca Linton; John N Brady
Tax interacts with P-TEFb in a novel manner to stimulate human T-lymphotropic virus type 1 transcription.
Journal of virology 2006;80(10):4781-91.
2006: Kevin D Welch; Timothy P Reilly; Mohammed Bourdi; Thomas Hays; Cynthia A Pise-Masison; Michael F Radonovich; John N Brady; David J Dix; Lance R Pohl
Genomic identification of potential risk factors during acetaminophen-induced liver disease in susceptible and resistant strains of mice.
Chemical research in toxicology 2006;19(2):223-33.
2006: Hyeon Ung Park; Soo-Jin Jeong; J-H Jeong; J H Chung; John N Brady
Human T-cell leukemia virus type 1 Tax attenuates gamma-irradiation-induced apoptosis through physical interaction with Chk2.
Oncogene 2006;25(3):438-47.
2006: Anne Gegonne; Jocelyn D Weissman; Meisheng Zhou; John N Brady; dinah singer
TAF7: a possible transcription initiation check-point regulator.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(3):602-7.
2006: Manabu Ohyama; Atsushi Terunuma; Christine L Tock; Michael F Radonovich; Cynthia A Pise-Masison; Steven B Hopping; John N Brady; Mark C Udey; Jonathan C Vogel
Characterization and isolation of stem cell-enriched human hair follicle bulge cells.
The Journal of clinical investigation 2006;116(1):249-60.
2005: Alexandra H Minn; Cynthia A Pise-Masison; Michael F Radonovich; John N Brady; Ping Wang; Christina Kendziorski; Anath Shalev
Gene expression profiling in INS-1 cells overexpressing thioredoxin-interacting protein.
Biochemical and biophysical research communications 2005;336(3):770-8.
2005: Soo-Jin Jeong; Cynthia A Pise-Masison; Michael F Radonovich; Hyeon Ung Park; John N Brady
Activated AKT regulates NF-kappaB activation, p53 inhibition and cell survival in HTLV-1-transformed cells.
Oncogene 2005;24(44):6719-28.
2005: Fatah Kashanchi; John N Brady
Transcriptional and post-transcriptional gene regulation of HTLV-1.
Oncogene 2005;24(39):5938-51.
2005: Panu E Kovanen; Lynn Young; Amin Al-Shami; Valentina Rovella; Cynthia A Pise-Masison; Michael F Radonovich; John Powell; Jacqueline Fu; John N Brady; Peter J Munson; Warren J Leonard
Global analysis of IL-2 target genes: identification of chromosomal clusters of expressed genes.
International immunology 2005;17(8):1009-21.
2005: Cynthia A Pise-Masison; Soo-Jin Jeong; John N Brady
Human T cell leukemia virus type 1: the role of Tax in leukemogenesis.
Archivum immunologiae et therapiae experimentalis 2005;53(4):283-96.
2005: Soo-Jin Jeong; Cynthia A Pise-Masison; Michael F Radonovich; Hyeon Ung Park; John N Brady
A novel NF-kappaB pathway involving IKKbeta and p65/RelA Ser-536 phosphorylation results in p53 Inhibition in the absence of NF-kappaB transcriptional activity.
The Journal of biological chemistry 2005;280(11):10326-32.
2005: Rong Zeng; Rosanne Spolski; Steven E Finkelstein; SangKon Oh; Panu E Kovanen; Christian S Hinrichs; Cynthia A Pise-Masison; Michael F Radonovich; John N Brady; Nicholas P Restifo; Jay A Berzofsky; Warren J Leonard
Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function.
The Journal of experimental medicine 2005;201(1):139-48.
2005: Cynthia A Pise-Masison; John N Brady
Setting the stage for transformation: HTLV-1 Tax inhibition of p53 function.
Frontiers in bioscience : a journal and virtual library 2005;10():919-30.
2004: Meisheng Zhou; Longwen Deng; Vincent Lacoste; Hyeon Ung Park; Anne Pumfery; Fatah Kashanchi; John N Brady; Ajit Kumar
Coordination of transcription factor phosphorylation and histone methylation by the P-TEFb kinase during human immunodeficiency virus type 1 transcription.
Journal of virology 2004;78(24):13522-33.
2004: Soo-Jin Jeong; Michael F Radonovich; John N Brady; Cynthia A Pise-Masison
HTLV-I Tax induces a novel interaction between p65/RelA and p53 that results in inhibition of p53 transcriptional activity.
Blood 2004;104(5):1490-7.
2004: Hanxin Lu; Cynthia A Pise-Masison; Rebecca Linton; Hyeon Ung Park; R Louis Schiltz; Vittorio Sartorelli; John N Brady
Tax relieves transcriptional repression by promoting histone deacetylase 1 release from the human T-cell leukemia virus type 1 long terminal repeat.
Journal of virology 2004;78(13):6735-43.
2004: Hyeon Ung Park; Jae-Hoon Jeong; Jay H Chung; John N Brady
Human T-cell leukemia virus type 1 Tax interacts with Chk1 and attenuates DNA-damage induced G2 arrest mediated by Chk1.
Oncogene 2004;23(29):4966-74.
2004: Kathleen M Dohoney; Claire Guillerm; Craig C Whiteford; Cem Elbi; Paul F Lambert; Gordon L Hager; John N Brady
Phosphorylation of p53 at serine 37 is important for transcriptional activity and regulation in response to DNA damage.
Oncogene 2004;23(1):49-57.
2003: Meisheng Zhou; Longwen Deng; Fatah Kashanchi; John N Brady; Aaron J Shatkin; Ajit Kumar
The Tat/TAR-dependent phosphorylation of RNA polymerase II C-terminal domain stimulates cotranscriptional capping of HIV-1 mRNA.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(22):12666-71.
2003: Iqbal H Chowdhury; Michael F Radonovich; Renaud Mahieux; Cynthia A Pise-Masison; Sumitra Muralidhar; John N Brady
P53 facilitates degradation of human T-cell leukaemia virus type I Tax-binding protein through a proteasome-dependent pathway.
The Journal of general virology 2003;84(Pt 4):897-906.
2002: Cynthia Ju; Timothy P Reilly; Mohammed Bourdi; Michael F Radonovich; John N Brady; John W George; Lance R Pohl
Protective role of Kupffer cells in acetaminophen-induced hepatic injury in mice.
Chemical research in toxicology 2002;15(12):1504-13.
2002: Hai-Hui Xue; Panu E Kovanen; Cynthia A Pise-Masison; Maria Berg; Michael F Radovich; John N Brady; Warren J Leonard
IL-2 negatively regulates IL-7 receptor alpha chain expression in activated T lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(21):13759-64.
2002: Dug Keun Lee; Byung-Chul Kim; John N Brady; Kuan-Teh Jeang; Seong-Jin Kim
Human T-cell lymphotropic virus type 1 tax inhibits transforming growth factor-beta signaling by blocking the association of Smad proteins with Smad-binding element.
The Journal of biological chemistry 2002;277(37):33766-75.
2002: Anath Shalev; Cynthia A Pise-Masison; Michael F Radonovich; Steven C Hoffmann; Boaz Hirshberg; John N Brady; David M Harlan
Oligonucleotide microarray analysis of intact human pancreatic islets: identification of glucose-responsive genes and a highly regulated TGFbeta signaling pathway.
Endocrinology 2002;143(9):3695-8.
2002: Hanxin Lu; Cynthia A Pise-Masison; Terace M Fletcher; R Louis Schiltz; Akhilesh K Nagaich; Michael F Radonovich; Gordon Hager; Philip A Cole; John N Brady
Acetylation of nucleosomal histones by p300 facilitates transcription from tax-responsive human T-cell leukemia virus type 1 chromatin template.
Molecular and cellular biology 2002;22(13):4450-62.
2002: Cynthia A Pise-Masison; Michael F Radonovich; Renaud Mahieux; Pramita Chatterjee; Craig C Whiteford; Janet Duvall; Claire Guillerm; Antoine Gessain; John N Brady
Transcription profile of cells infected with human T-cell leukemia virus type I compared with activated lymphocytes.
Cancer research 2002;62(12):3562-71.
2002: Diana C Bharucha; Meisheng Zhou; Sergei Nekhai; John N Brady; Ram R Shukla; Ajit Kumar
A protein phosphatase from human T cells augments tat transactivation of the human immunodeficiency virus type 1 long-terminal repeat.
Virology 2002;296(1):6-16.
2001: Renaud Mahieux; Cynthia A Pise-Masison; Antoine Gessain; John N Brady; R Olivier; Emmanuelle Perret; T Misteli; Christophe Nicot
Arsenic trioxide induces apoptosis in human T-cell leukemia virus type 1- and type 2-infected cells by a caspase-3-dependent mechanism involving Bcl-2 cleavage.
Blood 2001;98(13):3762-9.
2001: Timothy P Reilly; John N Brady; MR Marchick; Mohammed Bourdi; John W George; Michael F Radonovich; Cynthia A Pise-Masison; Lance R Pohl
A protective role for cyclooxygenase-2 in drug-induced liver injury in mice.
Chemical research in toxicology 2001;14(12):1620-8.
2001: Ming Zhou; Sergei Nekhai; D C Bharucha; Ajit Kumar; H Ge; D H Price; J M Egly; John N Brady
TFIIH inhibits CDK9 phosphorylation during human immunodeficiency virus type 1 transcription.
The Journal of biological chemistry 2001;276(48):44633-40.
2001: A Shalev; Leos Valásek; Cynthia A Pise-Masison; Michael F Radonovich; Lon Phan; J Clayton; H He; John N Brady; Alan G Hinnebusch; Katsura Asano
Saccharomyces cerevisiae protein Pci8p and human protein eIF3e/Int-6 interact with the eIF3 core complex by binding to cognate eIF3b subunits.
The Journal of biological chemistry 2001;276(37):34948-57.
2001: Gilles Lambert; N Sakai; Boris Vaisman; Edward B Neufeld; Benoit Marteyn; C C Chan; Beverly Paigen; Enrico Lupia; A Thomas; Liliane J Striker; Joan Blanchette-Mackie; Gyorgy Csako; John N Brady; R Costello; Gary E Striker; Alan T Remaley; H Bryan Brewer; Silvia Santamarina-Fojo
Analysis of glomerulosclerosis and atherosclerosis in lecithin cholesterol acyltransferase-deficient mice.
The Journal of biological chemistry 2001;276(18):15090-8.
2001: Timothy P Reilly; Mohammed Bourdi; John N Brady; Cynthia A Pise-Masison; Michael F Radonovich; John W George; Lance R Pohl
Expression profiling of acetaminophen liver toxicity in mice using microarray technology.
Biochemical and biophysical research communications 2001;282(1):321-8.
2001: Renaud Mahieux; Paul F Lambert; Emmanuel Agbottah; M A Halanski; Longwen Deng; Fatah Kashanchi; John N Brady
Cell cycle regulation of human interleukin-8 gene expression by the human immunodeficiency virus type 1 Tat protein.
Journal of virology 2001;75(4):1736-43.
2001: Cynthia A Pise-Masison; Renaud Mahieux; Michael F Radonovich; H Jiang; John N Brady
Human T-lymphotropic virus type I Tax protein utilizes distinct pathways for p53 inhibition that are cell type-dependent.
The Journal of biological chemistry 2001;276(1):200-5.
2000: Renaud Mahieux; Cynthia A Pise-Masison; Christophe Nicot; P Green; W W Hall; John N Brady
Inactivation of p53 by HTLV type 1 and HTLV type 2 Tax trans-activators.
AIDS research and human retroviruses 2000;16(16):1677-81.
2000: Cynthia A Pise-Masison; Renaud Mahieux; Michael F Radonovich; H Jiang; Janet Duvall; Claire Guillerm; John N Brady
Insights into the molecular mechanism of p53 inhibition by HTLV type 1 Tax.
AIDS research and human retroviruses 2000;16(16):1669-75.
2000: Christophe Nicot; Rene Opavsky; Renaud Mahieux; J M Johnson; John N Brady; Linda Wolff; Genoveffa Franchini
Tax oncoprotein trans-represses endogenous B-myb promoter activity in human T cells.
AIDS research and human retroviruses 2000;16(16):1629-32.
2000: Renaud Mahieux; Cynthia A Pise-Masison; Paul F Lambert; Christophe Nicot; L De Marchis; Antoine Gessain; P Green; W Hall; John N Brady
Differences in the ability of human T-cell lymphotropic virus type 1 (HTLV-1) and HTLV-2 tax to inhibit p53 function.
Journal of virology 2000;74(15):6866-74.
2000: Ming Zhou; M A Halanski; Michael F Radonovich; Fatah Kashanchi; Junmin Peng; D H Price; John N Brady
Tat modifies the activity of CDK9 to phosphorylate serine 5 of the RNA polymerase II carboxyl-terminal domain during human immunodeficiency virus type 1 transcription.
Molecular and cellular biology 2000;20(14):5077-86.
2000: Cynthia A Pise-Masison; Renaud Mahieux; H Jiang; M Ashcroft; Michael F Radonovich; Janet Duvall; Claire Guillerm; John N Brady
Inactivation of p53 by human T-cell lymphotropic virus type 1 Tax requires activation of the NF-kappaB pathway and is dependent on p53 phosphorylation.
Molecular and cellular biology 2000;20(10):3377-86.
2000: Christophe Nicot; Renaud Mahieux; Rene Opavsky; A Cereseto; Linda Wolff; John N Brady; Genoveffa Franchini
HTLV-I Tax transrepresses the human c-Myb promoter independently of its interaction with CBP or p300.
Oncogene 2000;19(17):2155-64.
2000: Ming Zhou; Fatah Kashanchi; H Jiang; H Ge; John N Brady
Phosphorylation of the RAP74 subunit of TFIIF correlates with Tat-activated transcription of the HIV-1 long terminal repeat.
Virology 2000;268(2):452-60.
2000: Fatah Kashanchi; Emmanuel Agbottah; Cynthia A Pise-Masison; Renaud Mahieux; Janet Duvall; Ajit Kumar; John N Brady
Cell cycle-regulated transcription by the human immunodeficiency virus type 1 Tat transactivator.
Journal of virology 2000;74(2):652-60.
1999: H Jiang; Hanxin Lu; R Louis Schiltz; Cynthia A Pise-Masison; Vasily Ogryzko; Yoshihiro Nakatani; John N Brady
PCAF interacts with tax and stimulates tax transactivation in a histone acetyltransferase-independent manner.
Molecular and cellular biology 1999;19(12):8136-45.
1998: Fatah Kashanchi; Janet Duvall; Roland P S Kwok; James R Lundblad; Richard H Goodman; John N Brady
The coactivator CBP stimulates human T-cell lymphotrophic virus type I Tax transactivation in vitro.
The Journal of biological chemistry 1998;273(51):34646-52.
1998: Paul F Lambert; Fatah Kashanchi; Michael F Radonovich; Ramin Shiekhattar; John N Brady
Phosphorylation of p53 serine 15 increases interaction with CBP.
The Journal of biological chemistry 1998;273(49):33048-53.
1998: Cynthia A Pise-Masison; Michael F Radonovich; Kazuyasu Sakaguchi; Ettore Appella; John N Brady
Phosphorylation of p53: a novel pathway for p53 inactivation in human T-cell lymphotropic virus type 1-transformed cells.
Journal of virology 1998;72(8):6348-55.
1998: Sumitra Muralidhar; Anne Pumfery; M Hassani; M Reza Sadaie; M Kishishita; John N Brady; Jay Doniger; P Medveczky; Leonard J Rosenthal
Identification of kaposin (open reading frame K12) as a human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus) transforming gene.
Journal of virology 1998;72(6):4980-8.
1998: Cynthia A Pise-Masison; Kyeong Sook Choi; Michael F Radonovich; Jürgen Dittmer; Seong-Jin Kim; John N Brady
Inhibition of p53 transactivation function by the human T-cell lymphotropic virus type 1 Tax protein.
Journal of virology 1998;72(2):1165-70.
1997: Cynthia A Pise-Masison; Jürgen Dittmer; K E Clemens; John N Brady
Physical and functional interaction between the human T-cell lymphotropic virus type 1 Tax1 protein and the CCAAT binding protein NF-Y.
Molecular and cellular biology 1997;17(3):1236-43.
1997: Jürgen Dittmer; Cynthia A Pise-Masison; K E Clemens; Kyeong Sook Choi; John N Brady
Interaction of human T-cell lymphotropic virus type I Tax, Ets1, and Sp1 in transactivation of the PTHrP P2 promoter.
The Journal of biological chemistry 1997;272(8):4953-8.
1997: Fatah Kashanchi; J Araujo; Jay Doniger; Sumitra Muralidhar; R Hoch; Samir N Khleif; E Mendelson; J Thompson; N Azumi; John N Brady; M Luppi; G Torelli; Leonard J Rosenthal
Human herpesvirus 6 (HHV-6) ORF-1 transactivating gene exhibits malignant transforming activity and its protein binds to p53.
Oncogene 1997;14(3):359-67.
1997: Fatah Kashanchi; M Reza Sadaie; John N Brady
Inhibition of HIV-1 transcription and virus replication using soluble Tat peptide analogs.
Virology 1997;227(2):431-8.
1996: Sumitra Muralidhar; Jay Doniger; E Mendelson; J C Araujo; Fatah Kashanchi; N Azumi; John N Brady; Leonard J Rosenthal
Human cytomegalovirus mtrII oncoprotein binds to p53 and down-regulates p53-activated transcription.
Journal of virology 1996;70(12):8691-700.
1996: M Tamami; P F Lindholm; John N Brady
The retinoblastoma gene product (Rb) induces binding of a conformationally inactive nuclear factor-kappaB.
The Journal of biological chemistry 1996;271(40):24551-6.
1996: K E Clemens; G Piras; Michael F Radonovich; Kyeong Sook Choi; J F Duvall; J DeJong; R Roeder; John N Brady
Interaction of the human T-cell lymphotropic virus type 1 tax transactivator with transcription factor IIA.
Molecular and cellular biology 1996;16(9):4656-64.
1996: G Piras; Jürgen Dittmer; Michael F Radonovich; John N Brady
Human T-cell leukemia virus type I Tax protein transactivates RNA polymerase III promoter in vitro and in vivo.
The Journal of biological chemistry 1996;271(34):20501-6.
1996: Fatah Kashanchi; Samir N Khleif; J F Duvall; M Reza Sadaie; Michael F Radonovich; M Cho; Malcolm Martin; S Y Chen; roberto weinmann; John N Brady
Interaction of human immunodeficiency virus type 1 Tat with a unique site of TFIID inhibits negative cofactor Dr1 and stabilizes the TFIID-TFIIA complex.
Journal of virology 1996;70(8):5503-10.
1996: A Mireskandari; R L Reid; Fatah Kashanchi; Jürgen Dittmer; W B Li; John N Brady
Isolation of a cDNA clone, TRX encoding a human T-cell lymphotrophic virus type-I Tax1 binding protein.
Biochimica et biophysica acta 1996;1306(1):9-13.
1996: P F Lindholm; M Tamami; J Makowski; John N Brady
Human T-cell lymphotropic virus type 1 Tax1 activation of NF-kappa B: involvement of the protein kinase C pathway.
Journal of virology 1996;70(4):2525-32.
1996: L Zhang; Fatah Kashanchi; Qimin Zhan; S Zhan; John N Brady; Albert J Fornace; Pankaj Seth; Lee Helman
Regulation of insulin-like growth factor II P3 promotor by p53: a potential mechanism for tumorigenesis.
Cancer research 1996;56(6):1367-73.
1995: John N Gnabre; John N Brady; D J Clanton; Y Ito; Jürgen Dittmer; R B Bates; Ru Chih C Huang
Inhibition of human immunodeficiency virus type 1 transcription and replication by DNA sequence-selective plant lignans.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(24):11239-43.
1995: J F Duvall; Fatah Kashanchi; Ales Cvekl; Michael F Radonovich; G Piras; John N Brady
Transactivation of the human T-cell lymphotropic virus type 1 Tax1-responsive 21-base-pair repeats requires Holo-TFIID and TFIIA.
Journal of virology 1995;69(8):5077-86.
1995: T Kevin Howcroft; L A Palmer; J Brown; Barbara L Rellahan; Fatah Kashanchi; John N Brady; dinah singer
HIV Tat represses transcription through Sp1-like elements in the basal promoter.
Immunity 1995;3(1):127-38.
1995: R A McKnight; M Spencer; Jürgen Dittmer; John N Brady; Robert J Wall; Lothar Hennighausen
An Ets site in the whey acidic protein gene promoter mediates transcriptional activation in the mammary gland of pregnant mice but is dispensable during lactation.
Molecular endocrinology (Baltimore, Md.) 1995;9(6):717-24.
1995: Ales Cvekl; Fatah Kashanchi; CM Sax; John N Brady; Joram Piatigorsky
Transcriptional regulation of the mouse alpha A-crystallin gene: activation dependent on a cyclic AMP-responsive element (DE1/CRE) and a Pax-6-binding site.
Molecular and cellular biology 1995;15(2):653-60.
1994: Barbara Ensoli; R Gendelman; Phillip Markham; Valeria Fiorelli; S Colombini; Mark Raffeld; Aurelio Aurelio Cafaro; H K Chang; John N Brady; Robert C Gallo
Synergy between basic fibroblast growth factor and HIV-1 Tat protein in induction of Kaposi's sarcoma.
Nature 1994;371(6499):674-80.
1994: G Piras; Fatah Kashanchi; Michael F Radonovich; J F Duvall; John N Brady
Transcription of the human T-cell lymphotropic virus type I promoter by an alpha-amanitin-resistant polymerase.
Journal of virology 1994;68(10):6170-9.
1994: Jürgen Dittmer; A Gégonne; Scott D Gitlin; Jacques Ghysdael; John N Brady
Regulation of parathyroid hormone-related protein (PTHrP) gene expression. Sp1 binds through an inverted CACCC motif and regulates promoter activity in cooperation with Ets1.
The Journal of biological chemistry 1994;269(34):21428-34.
1994: J. Paul Taylor; Roger J Pomerantz; Ganesh V Raj; Fatah Kashanchi; John N Brady; Shohreh Amini; Kamel Khalili
Central nervous system-derived cells express a kappa B-binding activity that enhances human immunodeficiency virus type 1 transcription in vitro and facilitates TAR-independent transactivation by Tat.
Journal of virology 1994;68(6):3971-81.
1994: Fatah Kashanchi; J Thompson; M Reza Sadaie; Jay Doniger; J Duvall; John N Brady; Leonard J Rosenthal
Transcriptional activation of minimal HIV-1 promoter by ORF-1 protein expressed from the SalI-L fragment of human herpesvirus 6.
Virology 1994;201(1):95-106.
1994: Fatah Kashanchi; R Shibata; E K Ross; John N Brady; Malcolm Martin
Second-site long terminal repeat (LTR) revertants of replication-defective human immunodeficiency virus: effects of revertant TATA box motifs on virus infectivity, LTR-directed expression, in vitro RNA synthesis, and binding of basal transcription factors TFIID and TFIIA.
Journal of virology 1994;68(5):3298-307.
1994: Fatah Kashanchi; G Piras; Michael F Radonovich; J F Duvall; A Fattaey; Cheng-Ming Chiang; R G Roeder; John N Brady
Direct interaction of human TFIID with the HIV-1 transactivator tat.
Nature 1994;367(6460):295-9.
1994: Fatah Kashanchi; J F Duvall; Jürgen Dittmer; A Mireskandari; R L Reid; Scott D Gitlin; John N Brady
Involvement of transcription factor YB-1 in human T-cell lymphotropic virus type I basal gene expression.
Journal of virology 1994;68(1):561-5.
1993: Scott D Gitlin; Jürgen Dittmer; R C Shin; John N Brady
Transcriptional activation of the human T-lymphotropic virus type I long terminal repeat by functional interaction of Tax1 and Ets1.
Journal of virology 1993;67(12):7307-16.
1993: R L Reid; P F Lindholm; A Mireskandari; Jürgen Dittmer; John N Brady
Stabilization of wild-type p53 in human T-lymphocytes transformed by HTLV-I.
Oncogene 1993;8(11):3029-36.
1993: Jürgen Dittmer; Scott D Gitlin; R L Reid; John N Brady
Transactivation of the P2 promoter of parathyroid hormone-related protein by human T-cell lymphotropic virus type I Tax1: evidence for the involvement of transcription factor Ets1.
Journal of virology 1993;67(10):6087-95.
1993: L M Connor; M N Oxman; John N Brady; Susan J Marriott
Twenty-one base pair repeat elements influence the ability of a Gal4-Tax fusion protein to transactivate the HTLV-I long terminal repeat.
Virology 1993;195(2):569-77.
1993: K A Gutekunst; Fatah Kashanchi; John N Brady; D P Bednarik
Transcription of the HIV-1 LTR is regulated by the density of DNA CpG methylation.
Journal of acquired immune deficiency syndromes 1993;6(6):541-9.
1993: Fatah Kashanchi; J F Duvall; P F Lindholm; Michael F Radonovich; John N Brady
Sequences downstream of the RNA initiation site regulate human T-cell lymphotropic virus type I basal gene expression.
Journal of virology 1993;67(5):2894-902.
1992: Fatah Kashanchi; J F Duvall; John N Brady
Electroporation of viral transactivator proteins into lymphocyte suspension cells.
Nucleic acids research 1992;20(17):4673-4.
1992: Susan J Marriott; D Trinh; John N Brady
Activation of interleukin-2 receptor alpha expression by extracellular HTLV-I Tax1 protein: a potential role in HTLV-I pathogenesis.
Oncogene 1992;7(9):1749-55.
1992: John N Brady
"Extracellular Tax1 protein stimulates NF-kB and expression of NF-kB-responsive Ig kappa and TNF beta genes in lymphoid cells".
AIDS research and human retroviruses 1992;8(5):724-7.
1992: P F Lindholm; R L Reid; John N Brady
Extracellular Tax1 protein stimulates tumor necrosis factor-beta and immunoglobulin kappa light chain expression in lymphoid cells.
Journal of virology 1992;66(3):1294-302.
1992: K A Boris-Lawrie; John N Brady; A Kumar
Sequences within the R region of the long terminal repeat activate basal transcription from the HIV-1 promoter.
Gene expression 1992;2(3):215-30.
1992: A Inamdar; J Thompson; Fatah Kashanchi; Jay Doniger; John N Brady; Leonard J Rosenthal
Identification of two promoters within human cytomegalovirus morphologic transforming region II.
Intervirology 1992;34(3):146-53.
1992: C A Bohan; Fatah Kashanchi; Barbara Ensoli; Luigi Buonaguro; K A Boris-Lawrie; John N Brady
Analysis of Tat transactivation of human immunodeficiency virus transcription in vitro.
Gene expression 1992;2(4):391-407.
1991: Scott D Gitlin; Rémy Bosselut; A Gégonne; Jacques Ghysdael; John N Brady
Sequence-specific interaction of the Ets1 protein with the long terminal repeat of the human T-lymphotropic virus type I.
Journal of virology 1991;65(10):5513-23.
1991: J Remenick; Michael F Radonovich; John N Brady
Human immunodeficiency virus Tat transactivation: induction of a tissue-specific enhancer in a nonpermissive cell line.
Journal of virology 1991;65(10):5641-6.
1991: Susan J Marriott; P F Lindholm; R L Reid; John N Brady
Soluble HTLV-I Tax1 protein stimulates proliferation of human peripheral blood lymphocytes.
The New biologist 1991;3(7):678-86.
1991: Scott D Gitlin; P F Lindholm; Susan J Marriott; John N Brady
Transdominant human T-cell lymphotropic virus type I TAX1 mutant that fails to localize to the nucleus.
Journal of virology 1991;65(5):2612-21.
1991: P F Lindholm; Susan J Marriott; Scott D Gitlin; John N Brady
Differential precipitation and zinc chelate chromatography purification of biologically active HTLV-I Tax1 expressed in E. coli.
Journal of biochemical and biophysical methods 1991;22(3):233-41.
1990: P F Lindholm; Susan J Marriott; Scott D Gitlin; C A Bohan; John N Brady
Induction of nuclear NF-kappa B DNA binding activity after exposure of lymphoid cells to soluble tax1 protein.
The New biologist 1990;2(11):1034-43.
1990: Susan J Marriott; P F Lindholm; K M Brown; Scott D Gitlin; J F Duvall; Michael F Radonovich; John N Brady
A 36-kilodalton cellular transcription factor mediates an indirect interaction of human T-cell leukemia/lymphoma virus type I TAX1 with a responsive element in the viral long terminal repeat.
Molecular and cellular biology 1990;10(8):4192-201.
1989: Susan J Marriott; John N Brady
Enhancer function in viral and cellular gene regulation.
Biochimica et biophysica acta 1989;989(2):97-110.
1989: Susan J Marriott; I Boros; J F Duvall; John N Brady
Indirect binding of human T-cell leukemia virus type I tax1 to a responsive element in the viral long terminal repeat.
Molecular and cellular biology 1989;9(10):4152-60.
1984: H Mishoe; John N Brady; Michael F Radonovich; N P Salzman
Simian virus 40 guanine-cytosine-rich sequences function as independent transcriptional control elements in vitro.
Molecular and cellular biology 1984;4(12):2911-20.
1984: H Mishoe; John N Brady; G Lancz; N P Salzman
In vitro transcription initiation by purified RNA polymerase II within the adenovirus 2 major late promoter region.
The Journal of biological chemistry 1984;259(4):2236-42.
1982: John N Brady; Michael F Radonovich; N P Salzman
Accurate transcription of simian virus 40 chromatin in a HeLa cell extract.
Journal of virology 1982;44(3):772-81.
1981: John N Brady; C A Lavialle; Michael F Radonovich; N P Salzman
Stable association of viral protein VP1 with simian virus 40 DNA.
Journal of virology 1981;39(2):432-7.
1980: John N Brady; C Lavialle; N P Salzman
Efficient transcription of a compact nucleoprotein complex isolated from purified simian virus 40 virions.
Journal of virology 1980;35(2):371-81.