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Guangji Wang

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Zhiyuan Tang; Guangji Wang; Mengqiu Wu; Lin Xu; Xiao Zheng; Xuefang Cheng; Yingchun Li; Huiying Liu; Haiping Hao
Absolute quantification of NAD(P)H:quinone oxidoreductase 1 in human tumor cell lines and tissues by liquid chromatography-mass spectrometry/mass spectrometry using both isotopic and non-isotopic internal standards.
Jie Cao; Wei R Chen; Sisi Cui; Changli Du; Yueqing Gu; Siwen Li; Zhiyu Qian; Junmei Tian; Shunan Wan; Guangji Wang
Targeted cancer therapy with a 2-deoxyglucose-based adriamycin complex.
Jianguo Sun; Jinghan Liu; Ying Peng; Fengyi Zhang; Yunxi Zhong; Guangji Wang
Quantitative determination of diterpenoid alkaloid Fuziline by hydrophilic interaction liquid chromatography (HILIC)-electrospray ionization mass spectrometry and its application to pharmacokinetic study in rats.

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2013: Zhiyuan Tang; Guangji Wang; Mengqiu Wu; Lin Xu; Xiao Zheng; Xuefang Cheng; Yingchun Li; Huiying Liu; Haiping Hao
Absolute quantification of NAD(P)H:quinone oxidoreductase 1 in human tumor cell lines and tissues by liquid chromatography-mass spectrometry/mass spectrometry using both isotopic and non-isotopic internal standards.
Analytica chimica acta 2013;772():59-67.
2013: Jie Cao; Wei R Chen; Sisi Cui; Changli Du; Yueqing Gu; Siwen Li; Zhiyu Qian; Junmei Tian; Shunan Wan; Guangji Wang
Targeted cancer therapy with a 2-deoxyglucose-based adriamycin complex.
Cancer research 2013;73(4):1362-73.
2013: Jianguo Sun; Jinghan Liu; Ying Peng; Fengyi Zhang; Yunxi Zhong; Guangji Wang
Quantitative determination of diterpenoid alkaloid Fuziline by hydrophilic interaction liquid chromatography (HILIC)-electrospray ionization mass spectrometry and its application to pharmacokinetic study in rats.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2013;913-914():55-60.
2013: Beth S Zha; Weibin Zha; Xiaoxuan Zhang; Phillip B Hylemon; Vijay Lyall; Martin Wabitsch; Xiaoshan Wan; Guangji Wang; Jun Zhou; Huiping Zhou
HIV protease inhibitors disrupt lipid metabolism by activating endoplasmic reticulum stress and inhibiting autophagy activity in adipocytes.
PloS one 2013;8(3):e59514.
2013: Weibin Zha; Qijin Zhao; Phillip M Gerk; Phillip B Hylemon; Xuyuan Liu; William M Pandak; Jian Shi; Elaine Studer; Guangji Wang; Yun Wang; Weiren Xu; Beth S Zha; Huiping Zhou
Inhibition of P-glycoprotein by HIV protease inhibitors increases intracellular accumulation of berberine in murine and human macrophages.
PloS one 2013;8(1):e54349.
2013: Kun Hao; Yan Liang; Qu Qi; Guangji Wang; Yuancheng Chen; Haiping Hao; Lin Xie
The pharmacokinetic-pharmacodynamic model of azithromycin for lipopolysaccharide-induced depressive-like behavior in mice.
PloS one 2013;8(1):e54981.
2013: Tian Zheng; Jun Zhou; Yahong Zhou; Yuexian Zuo; Jiye Aa; Bei Cao; Rongrong Gu; Mengjie Li; Linsheng Liu; Jian Shi; Runbing Sun; Guangji Wang; Xinwen Wang; Wenjing Xiao; Xiaoyi Yu; Chunyan Zhao; Xuanxuan Zhu
Metabolic phenotype of rats exposed to heroin and potential markers of heroin abuse.
Drug and alcohol dependence 2013;127(1-3):177-86.
2012: Xiao Zheng; Chen Dai; An Kang; Yan Liang; Yin Peng; Guangji Wang; Lin Xie; Tong Xie; Haiping Hao
Quantitative analysis of neurochemical panel in rat brain and plasma by liquid chromatography-tandem mass spectrometry.
Analytical chemistry 2012;84(22):10044-51.
2012: Liang Wu; Haiping Hao; Guangji Wang
LC/MS based tools and strategies on qualitative and quantitative analysis of herbal components in complex matrixes.
Current drug metabolism 2012;13(9):1251-65.
2012: Weibin Zha; Fang Zhou; Huiping Zhou; Beth S Zha; Guangji Wang
The cellular pharmacokinetics of HIV protease inhibitors: current knowledge and future perspectives.
Current drug metabolism 2012;13(8):1174-83.
2012: Jingwei Zhang; Fang Zhou; Xiaolan Wu; Gang Hao; Meng Lu; Haopeng Sun; Guangji Wang
Key role of nuclear factor-κB in the cellular pharmacokinetics of adriamycin in MCF-7/Adr cells: the potential mechanism for synergy with 20(S)-ginsenoside Rh2.
Drug metabolism and disposition: the biological fate of chemicals 2012;40(10):1900-8.
2012: Tong Xie; Xiao Zheng; Yuanyuan Zhou; Lin Xie; Jiye A; Chen Dai; Tianye Guan; Haiping Hao; Yan Liang; Linsheng Liu; Yanna Liu; Guangji Wang
Post acquisition data processing techniques for lipid analysis by quadrupole time-of-flight mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2012;905():43-53.
2012: Yanlei Zhao; Juan Li; Guangji Wang; Hua Yu; Wen Liu
Synthesis and characterization of a novel polydepsipeptide contained tri-block copolymer (mPEG-PLLA-PMMD) as self-assembly micelle delivery system for paclitaxel.
International journal of pharmaceutics 2012;430(1-2):282-91.
2012: Ping Wang; Lin Xie; Guanming Chen; Shi Jin; Jia Li; Li Liu; Xiaodong Liu; Xian Pan; Guangji Wang
Increased exposure of vitamin A by Chrysanthemum morifolium Ramat extract in rat was not via induction of CYP1A1, CYP1A2, and CYP2B1.
Journal of food science 2012;77(6):H121-7.
2012: Jingwei Zhang; Fang Zhou; Xiaolan Wu; Weibin Zha; Haiping Hao; Wei Ji; Meng Lu; Fang Niu; Guangji Wang
Pharmacokinetics-pharmacology disconnection of herbal medicines and its potential solutions with cellular pharmacokinetic-pharmacodynamic strategy.
Current drug metabolism 2012;13(5):558-76.
2012: Jiayu Tu; Aiyun Wang; Guangji Wang; Hongmei Wen; Jiye A; Bei Cao; Liuqing Di; Linsheng Liu
[Plasma metabonomics study of ischemic cerebral apoplexy rats treated with Tongsaimai pellets].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 2012;37(7):1028-33.
2012: Yuan Xie; Xilin Yao; Fang Zhou; Shan Jiang; An Kang; Guangji Wang; Hong Wang; Tong Xie; Haiping Hao
Cytochrome P450 dysregulations in thioacetamide-induced liver cirrhosis in rats and the counteracting effects of hepatoprotective agents.
Drug metabolism and disposition: the biological fate of chemicals 2012;40(4):796-802.
2012: Liping Ma; Ying Peng; Feng Shao; Jianguo Sun; Ping Wan; Xiaojin Wang; Hui Wu; Rong Zhang; Jianping Zhu; Yinci Zhu; Xuefang Cheng; Dong Feng; Xiaoling Hu; Guangji Wang
Glucuronidation of edaravone by human liver and kidney microsomes: biphasic kinetics and identification of UGT1A9 as the major UDP-glucuronosyltransferase isoform.
Drug metabolism and disposition: the biological fate of chemicals 2012;40(4):734-41.
2012: Ping Gong; Nan Cui; Kun Hao; Yan Liang; Weiguo Tang; Guangji Wang; Liang Wu; Xiangyang Xu; Haiping Hao
Chemicalome and metabolome matching approach to elucidating biological metabolic networks of complex mixtures.
Analytical chemistry 2012;84(6):2995-3002.
2012: Tong Xie; Xiao Zheng; Lin Xie; Jiye A; Chen Dai; Ping Gong; Haiping Hao; An Kang; Yan Liang; Linsheng Liu; Guangji Wang
Rapid identification of ophiopogonins and ophiopogonones in Ophiopogon japonicus extract with a practical technique of mass defect filtering based on high resolution mass spectrometry.
Journal of chromatography. A 2012;1227():234-44.
2012: Linsheng Liu; Jian Shi; Runbin Sun; Jiye Aa; Bei Cao; Rongrong Gu; Gang Hao; Mengjie Li; Xinwen Wang; Liang Wu; Wenjing Xiao; Xiaoyi Yu; Chunyan Zhao; Tian Zheng; Jun Zhou; Xuanxuan Zhu; Guangji Wang
Prediction of the pharmacokinetic parameters of triptolide in rats based on endogenous molecules in pre-dose baseline serum.
PloS one 2012;7(8):e43389.
2012: Fang Liu; Huiying Liu; Miao Liu; Guangji Wang; Qiong Wang; Mengqiu Wu; Xiaolan Wu; Guo Yu; Xuefang Cheng; Ke Liao; Haiping Hao
An NQO1-initiated and p53-independent apoptotic pathway determines the anti-tumor effect of tanshinone IIA against non-small cell lung cancer.
PloS one 2012;7(7):e42138.
2012: Jingwei Zhang; Fang Zhou; Xiaolan Wu; Meng Lu; Fang Niu; Jianguo Sun; Guangji Wang
Stereoselective regulations of P-glycoprotein by ginsenoside Rh2 epimers and the potential mechanisms from the view of pharmacokinetics.
PloS one 2012;7(4):e35768.
2012: Jingwei Zhang; Xiaoxuan Zhang; Fang Zhou; Xiaolan Wu; Beth S Zha; Yuancheng Chen; Gang Hao; Meng Lu; Fang Niu; Ying Peng; Jianguo Sun; Yuan Sun; Guangji Wang
Cellular pharmacokinetic mechanisms of adriamycin resistance and its modulation by 20(S)-ginsenoside Rh2 in MCF-7/Adr cells.
British journal of pharmacology 2012;165(1):120-34.
2011: Chen Dai; Gang Ding; Tianye Guan; An Kang; Chunzhu Li; Yan Liang; Wenjun Liu; Zhaoqing Meng; Guangji Wang; Wei Xiao; Lin Xie; Tong Xie; Juan Zhang; Li Zhao; Qijin Zhao; Xiao Zheng; Jia Xu
Validated liquid chromatography mass spectrometry method for quantitative determination of strictosamide in dog plasma and its application to pharmacokinetic study.
Biomedical chromatography : BMC 2011;25(12):1338-42.
2011: Shiqing Sun; Zhiyuan Tang; Xiaohu Chen; Ping Gong; Haiping Hao; Feiyan Li; Haibo Shi; Guangji Wang
Protocatechualdehyde synergizes with aspirin at the platelet cyclooxygenase-1 level.
Planta medica 2011;77(17):1898-904.
2011: Haiping Hao; Ping Li; Xiao Zheng; Guangji Wang
Translational research insights into pharmacokinetic herb-drug interactions.
Current drug metabolism 2011;12(9):850-70.
2011: Haiping Hao; Shan Jiang; Shiqing Sun; Yuan Xie; Lifang Zhang; Xueyan Zhou; Ping Gong; Guangji Wang
Thioacetamide intoxication triggers transcriptional up-regulation but enzyme inactivation of UDP-glucuronosyltransferases.
Drug metabolism and disposition: the biological fate of chemicals 2011;39(10):1815-22.
2011: Fang Zhou; Peng Li; Fang Niu; Guangji Wang; Xiaolan Wu; Jingwei Zhang; Michael S Roberts
Toward a new age of cellular pharmacokinetics in drug discovery.
Drug metabolism reviews 2011;43(3):335-45.
2011: Xiao Zheng; Lianming Xu; Yan Liang; Wei Xiao; Lin Xie; Yan Zhang; Li Zhao; Liang Cao; Jun Chen; Guangji Wang
Quantitative determination and pharmacokinetic study of solamargine in rat plasma by liquid chromatography-mass spectrometry.
Journal of pharmaceutical and biomedical analysis 2011;55(5):1157-62.
2011: Bei Cao; Jiye Aa; Guangji Wang; Xiaolan Wu; Linsheng Liu; Mengjie Li; Jian Shi; Xinwen Wang; Chunyan Zhao; Tian Zheng; Sheng Guo; Jinao Duan
GC-TOFMS analysis of metabolites in adherent MDCK cells and a novel strategy for identifying intracellular metabolic markers for use as cell amount indicators in data normalization.
Analytical and bioanalytical chemistry 2011;400(9):2983-93.
2011: Yan Liang; Wei Xiao; Chen Dai; Lin Xie; Gang Ding; Guangji Wang; Zhaoqing Meng; Juan Zhang; An Kang; Tong Xie; Yanna Liu; Yuanyuan Zhou; Wenjun Liu; Li Zhao; Jia Xu
Structural identification of the metabolites for strictosamide in rats bile by an ion trap-TOF mass spectrometer and mass defect filter technique.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2011;879(20):1819-22.
2011: Yan Liang; Guangji Wang; Lin Xie; Longsheng Sheng
Recent development in liquid chromatography/mass spectrometry and emerging technologies for metabolite identification.
Current drug metabolism 2011;12(4):329-44.
2011: Rong Zhang; Jianguo Sun; Liping Ma; Xiaolan Wu; Guoyu Pan; Haiping Hao; Fang Zhou; Jiye A; Changhui Liu; Hua Ai; Lili Shang; Haiyan Gao; Ying Peng; Ping Wan; Hui Wu; Guangji Wang
Induction of cytochromes P450 1A1 and 1A2 by tanshinones in human HepG2 hepatoma cell line.
Toxicology and applied pharmacology 2011;252(1):18-27.
2011: Nan Hu; Shanshan Xie; Li Liu; Xinting Wang; Xian Pan; Guanming Chen; Lulu Zhang; Haiyan Liu; Xiaodong Liu; Xiaodong Liu; Lin Xie; Guangji Wang
Opposite effect of diabetes mellitus induced by streptozotocin on oral and intravenous pharmacokinetics of verapamil in rats.
Drug metabolism and disposition: the biological fate of chemicals 2011;39(3):419-25.
2011: An Kang; Yan Liang; Chen Dai; Haiping Hao; Xiaolan Wu; Lin Xie; Tong Xie; Yuan Xie; Qijin Zhao; Xiao Zheng; Guangji Wang
Peripheral anti-inflammatory effects explain the ginsenosides paradox between poor brain distribution and anti-depression efficacy.
Journal of neuroinflammation 2011;8():100.
2011: Xian Pan; Nan Hu; Li Liu; Xiaodong Liu; Ping Wang; Lin Xie; Guangji Wang
A physiologically based pharmacokinetic model characterizing mechanism-based inhibition of CYP1A2 for predicting theophylline/antofloxacin interaction in both rats and humans.
Drug metabolism and pharmacokinetics 2011;26(4):387-98.
2010: Furong Qiu; Rong Zhang; Guangji Wang; Chenglu Gao; Jianguo Sun; Jian Jiang; Yueming Ma
Activation of CYP3A-mediated testosterone 6β-hydroxylation by tanshinone IIA and midazolam 1-hydroxylation by cryptotanshinone in human liver microsomes.
Xenobiotica; the fate of foreign compounds in biological systems 2010;40(12):800-6.
2010: Jingwei Zhang; Fang Zhou; Xiaolan Wu; Yi Gu; Hua Ai; Yuanting Zheng; Yannan Li; Xiaoxuan Zhang; Gang Hao; Jianguo Sun; Ying Peng; Guangji Wang
20(S)-ginsenoside Rh2 noncompetitively inhibits P-glycoprotein in vitro and in vivo: a case for herb-drug interactions.
Drug metabolism and disposition: the biological fate of chemicals 2010;38(12):2179-87.
2010: Linsheng Liu; Jiye Aa; Guangji Wang; Bei Yan; Ying Zhang; Xinwen Wang; Chunyan Zhao; Bei Cao; Jian Shi; Mengjie Li; Tian Zheng; Yuanting Zheng; Gang Hao; Fang Zhou; Jianguo Sun; Zimei Wu
Differences in metabolite profile between blood plasma and serum.
Analytical biochemistry 2010;406(2):105-12.
2010: Ye Xiong; Ling Shen; Kristina J Liu; Patrick Tso; Yuqing Xiong; Guangji Wang; Stephen C Woods; Min Liu
Antiobesity and antihyperglycemic effects of ginsenoside Rb1 in rats.
Diabetes 2010;59(10):2505-12.
2010: Haiping Hao; Li Lai; Chaonan Zheng; Qiong Wang; Guo Yu; Xueyan Zhou; Liang Wu; Ping Gong; Guangji Wang
Microsomal cytochrome p450-mediated metabolism of protopanaxatriol ginsenosides: metabolite profile, reaction phenotyping, and structure-metabolism relationship.
Drug metabolism and disposition: the biological fate of chemicals 2010;38(10):1731-9.
2010: Yan Liang; Haiping Hao; Lin Xie; An Kang; Tong Xie; Xiao Zheng; Chen Dai; Kun Hao; Longsheng Sheng; Guangji Wang
Development of a systematic approach to identify metabolites for herbal homologs based on liquid chromatography hybrid ion trap time-of-flight mass spectrometry: gender-related difference in metabolism of Schisandra lignans in rats.
Drug metabolism and disposition: the biological fate of chemicals 2010;38(10):1747-59.
2010: Yuan Xie; Haiping Hao; An Kang; Yan Liang; Tong Xie; Shiqing Sun; Chen Dai; Xiao Zheng; Lin Xie; Juan Li; Guangji Wang
Integral pharmacokinetics of multiple lignan components in normal, CCl4-induced hepatic injury and hepatoprotective agents pretreated rats and correlations with hepatic injury biomarkers.
Journal of ethnopharmacology 2010;131(2):290-9.
2010: Xiao Wu; Hui Chen; Jianguo Sun; Ying Peng; Yan Liang; Guangji Wang; Jizhou Wu; Peng Zhang
Development and validation of a liquid chromatography-mass spectrometry method for the determination of verticinone in rat plasma and its application to pharmacokinetic study.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2010;878(23):2067-71.
2010: Yan Liang; Haiping Hao; An Kang; Lin Xie; Tong Xie; Xiao Zheng; Chen Dai; Leren Wan; Longsheng Sheng; Guangji Wang
Qualitative and quantitative determination of complicated herbal components by liquid chromatography hybrid ion trap time-of-flight mass spectrometry and a relative exposure approach to herbal pharmacokinetics independent of standards.
Journal of chromatography. A 2010;1217(30):4971-9.
2010: Qiong Wang; Haiping Hao; Xuanxuan Zhu; Guo Yu; Li Lai; Yitong Liu; Yuxin Wang; Shan Jiang; Guangji Wang
Regioselective glucuronidation of tanshinone iia after quinone reduction: identification of human UDP-glucuronosyltransferases, species differences, and interaction potential.
Drug metabolism and disposition: the biological fate of chemicals 2010;38(7):1132-40.
2010: Bokai Lei; Weibin Zha; Yun Wang; Cong Wen; Elaine Studer; Xuan Wang; Fang Jin; Guangji Wang; Luyong Zhang; Huiping Zhou
Development of a novel self-microemulsifying drug delivery system for reducing HIV protease inhibitor-induced intestinal epithelial barrier dysfunction.
Molecular pharmaceutics 2010;7(3):844-53.
2010: Furong Qiu; Guangji Wang; Rong Zhang; Jianguo Sun; Jian Jiang; Yueming Ma
Effect of danshen extract on the activity of CYP3A4 in healthy volunteers.
British journal of clinical pharmacology 2010;69(6):656-62.
2010: Sen Yu; Yunli Yu; Li Liu; Xinting Wang; Shousi Lu; Yan Liang; Xiaodong Liu; Lin Xie; Guangji Wang
Increased plasma exposures of five protoberberine alkaloids from Coptidis Rhizoma in streptozotocin-induced diabetic rats: is P-GP involved?
Planta medica 2010;76(9):876-81.
2010: Yuanting Zheng; Fang Zhou; Xiaolan Wu; Xiaozhou Wen; Yannan Li; Bei Yan; Jingwei Zhang; Gang Hao; Wencai Ye; Guangji Wang
23-Hydroxybetulinic acid from Pulsatilla chinensis (Bunge) Regel synergizes the antitumor activities of doxorubicin in vitro and in vivo.
Journal of ethnopharmacology 2010;128(3):615-22.
2010: Xinyue Jing; Xiang Liu; Tao Wen; Shanshan Xie; Dan Yao; Xiaodong Liu; Guangji Wang; Lin Xie
Combined effects of epileptic seizure and phenobarbital induced overexpression of P-glycoprotein in brain of chemically kindled rats.
British journal of pharmacology 2010;159(7):1511-22.
2010: Yunli Yu; Li Liu; Xinting Wang; Xiaodong Liu; Xiaodong Liu; Lin Xie; Guangji Wang
Modulation of glucagon-like peptide-1 release by berberine: in vivo and in vitro studies.
Biochemical pharmacology 2010;79(7):1000-6.
2010: Yiwen Zheng; Shweta Vagal; Xuan-xuan Zhu; Catherine de Waele; paul smith; Guangji Wang; Ming Zhang; Cynthia L Darlington
The effects of the Chinese herbal medicine EMF01 on salicylate-induced tinnitus in rats.
Journal of ethnopharmacology 2010;128(2):545-8.
2010: Yuanwei Jia; Haitang Xie; Guangji Wang; Jianguo Sun; Wei Wang; Huang Qing; Xuan Wang; Hao Yang; Meijuan Xu; Yi Gu; Chen Yao; Jie Shen
Quantitative determination of helicid in rat biosamples by liquid chromatography electrospray ionization mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2010;878(9-10):791-7.
2010: Shenghua Gu; Jiye A; Guangji Wang; Weibin Zha; Bei Yan; Ying Zhang; Hongcan Ren; Bei Cao; Linsheng Liu
Metabonomic profiling of liver metabolites by gas chromatography-mass spectrometry and its application to characterizing hyperlipidemia.
Biomedical chromatography : BMC 2010;24(3):245-52.
2010: Jiye A; Sixuan Qian; Guangji Wang; Bei Yan; Sujiang Zhang; Qing Huang; Lingna Ni; Weibin Zha; Linsheng Liu; Bei Cao; Ming Hong; Hanxin Wu; Hua Lu; Jian Shi; Mengjie Li; Jianyong Li
Chronic myeloid leukemia patients sensitive and resistant to imatinib treatment show different metabolic responses.
PloS one 2010;5(10):e13186.
2010: Weibin Zha; Guang Liang; Jian Xiao; Elaine J Studer; Phillip B Hylemon; William M Pandak; Guangji Wang; Xiaokun Li; Huiping Zhou
Berberine inhibits HIV protease inhibitor-induced inflammatory response by modulating ER stress signaling pathways in murine macrophages.
PloS one 2010;5(2):e9069.
2010: Xudong Wu; Lixin Sun; Weibin Zha; Elaine Studer; Emily Gurley; Li Chen; Xuan Wang; Phillip B Hylemon; William M Pandak; Arun J Sanyal; Luyong Zhang; Guangji Wang; Jie Chen; Jian-Ying Wang; Huiping Zhou
HIV protease inhibitors induce endoplasmic reticulum stress and disrupt barrier integrity in intestinal epithelial cells.
Gastroenterology 2010;138(1):197-209.
2009: Yuxin Wang; Haiping Hao; Guangji Wang; Pengfei Tu; Yong Jiang; Yan Liang; Liang Dai; Hao Yang; Li Lai; Chaonan Zheng; Qiong Wang; Nan Cui; Yitong Liu
An approach to identifying sequential metabolites of a typical phenylethanoid glycoside, echinacoside, based on liquid chromatography-ion trap-time of flight mass spectrometry analysis.
Talanta 2009;80(2):572-80.
2009: P He; H H Wang; S G Liu; J X Shi; Guangji Wang; Meng-Lian Gong
Visible-light excitable europium(III) complexes with 2,7-positional substituted carbazole group-containing ligands.
Inorganic chemistry 2009;48(23):11382-7.
2009: Li Lai; Haiping Hao; Qiong Wang; Chaonao Zheng; Fang Zhou; Yitong Liu; Yuxin Wang; Guo Yu; An Kang; Ying Peng; Guangji Wang; Xijing Chen
Effects of short-term and long-term pretreatment of Schisandra lignans on regulating hepatic and intestinal CYP3A in rats.
Drug metabolism and disposition: the biological fate of chemicals 2009;37(12):2399-407.
2009: Bei Yan; Jiye A; Haiping Hao; Guangji Wang; XuanXuan Zhu; WeiBin Zha; LinSheng Liu; EnZe Guan; Ying Zhang; ShengHua Gu; Qing Huang; Yuanting Zheng
Metabonomic phenotype and identification of "heart blood stasis obstruction pattern" and "qi and yin deficiency pattern" of myocardial ischemia rat models.
Science in China. Series C, Life sciences / Chinese Academy of Sciences 2009;52(11):1081-90.
2009: Yitong Liu; Haiping Hao; Hongguang Xie; Hua Lv; Changxiao Liu; Guangji Wang
Oxidative demethylenation and subsequent glucuronidation are the major metabolic pathways of berberine in rats.
Journal of pharmaceutical sciences 2009;98(11):4391-401.
2009: Weibin Zha; Jiye A; Guangji Wang; Bei Yan; Shenghua Gu; Xuanxuan Zhu; Haiping Hao; Qing Huang; Jianguo Sun; Ying Zhang; Bei Cao; Hongcan Ren
Metabonomic characterization of early atherosclerosis in hamsters with induced cholesterol.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2009;14(6):372-80.
2009: Chunhua Xia; Jianguo Sun; Guangji Wang; Lili Shang; Xiaoxuan Zhang; Rong Zhang; Xiaojin Wang; Haiping Hao; Lin Xie
Differential effect of Shenmai injection, a herbal preparation, on the cytochrome P450 3A-mediated 1'-hydroxylation and 4-hydroxylation of midazolam.
Chemico-biological interactions 2009;180(3):440-8.
2009: Jian Peng; Qi Qi; Qidong You; Rong Hu; Wenyuan Liu; Feng Feng; Guangji Wang; Qinglong Guo
Subchronic toxicity and plasma pharmacokinetic studies on wogonin, a natural flavonoid, in Beagle dogs.
Journal of ethnopharmacology 2009;124(2):257-62.
2009: Lian-Wen Qi; Xiao-Jie Gu; Ping Li; Yan Liang; Haiping Hao; Guangji Wang
Structural characterization of pregnane glycosides from Cynanchum auriculatum by liquid chromatography on a hybrid ion trap time-of-flight mass spectrometer.
Rapid communications in mass spectrometry : RCM 2009;23(14):2151-60.
2009: Li Chen; Sirikalaya Jarujaron; Xudong Wu; Lixin Sun; Weibin Zha; Guang Liang; Xuan Wang; Emily C Gurley; Elaine Studer; Phillip B Hylemon; William M Pandak; Luyong Zhang; Guangji Wang; Xiaokun Li; Paul Dent; Huiping Zhou
HIV protease inhibitor lopinavir-induced TNF-alpha and IL-6 expression is coupled to the unfolded protein response and ERK signaling pathways in macrophages.
Biochemical pharmacology 2009;78(1):70-7.
2009: Ying Zhang; Jiye A; Guangji Wang; Qing Huang; Bei Yan; Weibin Zha; Shenghua Gu; Linsheng Liu; Hongcan Ren; Meiting Ren; Longsheng Sheng
Organic solvent extraction and metabonomic profiling of the metabolites in erythrocytes.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2009;877(18-19):1751-7.
2009: Hao Yang; Guangji Wang; Haiping Hao; Pengfei Tu; Yong Jiang; Qiong Wang; Yan Zhang; Chaonan Zheng; Yuxin Wang; Liang Dai
A sensitive and specific liquid chromatography/tandem mass spectrometry method for determination of echinacoside and its pharmacokinetic application in rats.
Biomedical chromatography : BMC 2009;23(6):630-7.
2009: Li Lai; Haiping Hao; Yitong Liu; Chaonan Zheng; Qiong Wang; Guangji Wang; Xijin Chen
Characterization of pharmacokinetic profiles and metabolic pathways of 20(S)-ginsenoside Rh1 in vivo and in vitro.
Planta medica 2009;75(8):797-802.
2009: Qian Zhang; Jeffrey E Grice; Guangji Wang; Michael S Roberts
Cutaneous metabolism in transdermal drug delivery.
Current drug metabolism 2009;10(3):227-35.
2009: Qi Qi; Jian Peng; Wei Liu; Qidong You; Yong Yang; Na Lu; Guangji Wang; Qinglong Guo
Toxicological studies of wogonin in experimental animals.
Phytotherapy research : PTR 2009;23(3):417-22.
2009: Bei Yan; Jiye A; Guangji Wang; Huali Lu; Xiaoping Huang; Yi Liu; Weibin Zha; Haiping Hao; Ying Zhang; Linsheng Liu; Shenghua Gu; Qing Huang; Yuanting Zheng; Jianguo Sun
Metabolomic investigation into variation of endogenous metabolites in professional athletes subject to strength-endurance training.
Journal of applied physiology (Bethesda, Md. : 1985) 2009;106(2):531-8.
2009: Chaonan Zheng; Haiping Hao; Xuan Wang; Xiaolan Wu; Guangji Wang; Guowei Sang; Yan Liang; Lin Xie; Chunhua Xia; Xilin Yao
Diagnostic fragment-ion-based extension strategy for rapid screening and identification of serial components of homologous families contained in traditional Chinese medicine prescription using high-resolution LC-ESI- IT-TOF/MS: Shengmai injection as an example.
Journal of mass spectrometry : JMS 2009;44(2):230-44.
2009: Haiyan Liu; Huiwen Yang; Dianlei Wang; Yuchun Liu; Xiaodong Liu; Yang Li; Lin Xie; Guangji Wang
Insulin regulates P-glycoprotein in rat brain microvessel endothelial cells via an insulin receptor-mediated PKC/NF-kappaB pathway but not a PI3K/Akt pathway.
European journal of pharmacology 2009;602(2-3):277-82.
2009: Yang Lu; Jing Zhu; Xijing Chen; Ning Li; Feifei Fu; Jiake He; Guangji Wang; Lingli Zhang; Yi Zheng; Zhixia Qiu; Xue Yu; Deen Han; Lei Wu
Identification of human UDP-glucuronosyltransferase isoforms responsible for the glucuronidation of glycyrrhetinic acid.
Drug metabolism and pharmacokinetics 2009;24(6):523-8.
2009: Li Lai; Yitong Liu; Haiping Hao; Guangji Wang; Xijing Chen; Hongcan Ren
Determination of 20(S)-ginsenoside Rh1 and its aglycone 20(S)-protopanaxatriol in rat plasma by sensitive LC-APCI-MS method and its application to pharmacokinetic study.
European journal of mass spectrometry (Chichester, England) 2009;15(1):57-65.
2008: Haiping Hao; Nan Cui; Guangji Wang; Binren Xiang; Yan Liang; Xiangyang Xu; Hui Zhang; Jun Yang; Chaonan Zheng; Liang Wu; Ping Gong; Wei Wang
Global detection and identification of nontarget components from herbal preparations by liquid chromatography hybrid ion trap time-of-flight mass spectrometry and a strategy.
Analytical chemistry 2008;80(21):8187-94.
2008: Yihong Lu; Jiye A; Guangji Wang; Haiping Hao; Qing Huang; Bei Yan; Weibin Zha; Shenghua Gu; Hongcan Ren; Ying Zhang; Xialei Fan; Mei Zhang; Kun Hao
Gas chromatography/time-of-flight mass spectrometry based metabonomic approach to differentiating hypertension- and age-related metabolic variation in spontaneously hypertensive rats.
Rapid communications in mass spectrometry : RCM 2008;22(18):2882-8.
2008: Jin Yang; Liang Zhou; Jiping Wang; Guangji Wang; Andrew K Davey
The disposition of diammonium glycyrrhizinate and glycyrrhetinic acid in the isolated perfused rat intestine and liver.
Planta medica 2008;74(11):1351-6.
2008: A Jiye; Qing Huang; Guangji Wang; Weibin Zha; Bei Yan; Hongcan Ren; Shenghua Gu; Ying Zhang; Qi Zhang; Feng Shao; Longsheng Sheng; Jianguo Sun
Global analysis of metabolites in rat and human urine based on gas chromatography/time-of-flight mass spectrometry.
Analytical biochemistry 2008;379(1):20-6.
2008: Furong Qiu; Rong Zhang; Jianguo Sun; A Jiye; Haiping Hao; Ying Peng; Hua Ai; Guangji Wang
Inhibitory effects of seven components of danshen extract on catalytic activity of cytochrome P450 enzyme in human liver microsomes.
Drug metabolism and disposition: the biological fate of chemicals 2008;36(7):1308-14.
2008: Yang Lu; Juan Li; Guangji Wang
In vitro and in vivo evaluation of mPEG-PLA modified liposomes loaded glycyrrhetinic acid.
International journal of pharmaceutics 2008;356(1-2):274-81.
2008: Y Liu; H Liu; J Yang; Xiaodong Liu; S Lu; T Wen; Lin Xie; Guangji Wang
Increased amyloid beta-peptide (1-40) level in brain of streptozotocin-induced diabetic rats.
Neuroscience 2008;153(3):796-802.
2008: Haiyan Liu; Xiaodong Liu; Lee Jia; Yuchun Liu; Huiwen Yang; Guangji Wang; Lin Xie
Insulin therapy restores impaired function and expression of P-glycoprotein in blood-brain barrier of experimental diabetes.
Biochemical pharmacology 2008;75(8):1649-58.
2008: Rui Wang; Haiping Hao; Guangji Wang; Haitang Xie; Meijuan Xu; Wei Wang; Hui He; Xiaoyu Li
Pharmacokinetics, tissue distribution and excretion of a new photodynamic drug deuxemether.
Journal of photochemistry and photobiology. B, Biology 2008;90(3):179-86.
2008: Hua Lv; Guangji Wang; Xiaolan Wu; Lin Xie; Chenrong Huang; Hao Li; Yan Liang; Haiping Hao; Jie Sun
Transport characteristics of ginkgolide B by Caco-2 cells and examination of ginkgolide B oral absorption potential using rat in situ intestinal loop method.
International journal of pharmaceutics 2008;351(1-2):31-5.
2008: Meijuan Xu; Guangji Wang; Haitang Xie; Qing Huang; Wei Wang; Yuanwei Jia
Pharmacokinetic comparisons of schizandrin after oral administration of schizandrin monomer, Fructus Schisandrae aqueous extract and Sheng-Mai-San to rats.
Journal of ethnopharmacology 2008;115(3):483-8.
2008: Chunhua Xia; Guangji Wang; Jianguo Sun; Haiping Hao; Yuqing Xiong; Shenghua Gu; Lili Shang; Chaonan Zheng
Simultaneous determination of ginsenoside Rg1, Re, Rd, Rb1 and ophiopogonin D in rat plasma by liquid chromatography/electrospray ionization mass spectrometric method and its application to pharmacokinetic study of 'SHENMAI' injection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2008;862(1-2):72-8.
2008: Furong Qiu; Guangji Wang; Yanan Zhao; Hua Sun; Guoguang Mao; Jiyi A; Jian Sun
Effect of danshen extract on pharmacokinetics of theophylline in healthy volunteers.
British journal of clinical pharmacology 2008;65(2):270-4.
2008: Jing Jing; Weichao Ren; Xijing Chen; Yue Wang; Qiaoling Yu; Guangji Wang; Andrew K Davey; Jiping Wang; Ning Jing
Glucuronide-sulfate diconjugate as a novel metabolite of glycyrrhetic acid in rat bile.
Drug metabolism and pharmacokinetics 2008;23(3):175-80.
2008: Chaonan Zheng; Haiping Hao; Guangji Wang; Guowei Sang; Jianguo Sun; Peng Li; Jing Li
Chiral separation of ibuprofen and chiral pharmacokinetics in healthy Chinese volunteers.
European journal of drug metabolism and pharmacokinetics 2008;33(1):45-51.
2008: Sen Yu; Li Liu; Tao Wen; Yuchun Liu; Dianlei Wang; Yuxian He; Yan Liang; Xiaodong Liu; Lin Xie; Guangji Wang; Wenzhi Wei
Development and validation of a liquid chromatographic/electrospray ionization mass spectrometric method for the determination of salidroside in rat plasma: application to the pharmacokinetics study.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2008;861(1):10-5.
2007: Xue-Qing Yu; Charlie Changli Xue; Guangji Wang; Shu-Feng Zhou
Multidrug resistance associated proteins as determining factors of pharmacokinetics and pharmacodynamics of drugs.
Current drug metabolism 2007;8(8):787-802.
2007: Shu-Feng Zhou; Charlie Changli Xue; Xue-Qing Yu; Chunguang Li; Guangji Wang
Clinically important drug interactions potentially involving mechanism-based inhibition of cytochrome P450 3A4 and the role of therapeutic drug monitoring.
Therapeutic drug monitoring 2007;29(6):687-710.
2007: Haiping Hao; Guangji Wang; Nan Cui; Jing Li; Zuoqi Ding
Determination of sodium tanshinone IIA sulfonate in plasma by liquid chromatography-electrospray ionisation-tandem mass spectrometry.
Biomedical chromatography : BMC 2007;21(11):1172-9.
2007: Bei Yan; Guangji Wang; Jiye A; Lin Xie; Haiping Hao; Yan Liang; Jianguo Sun; Xiaoyu Li; Yuanting Zheng
Construction of the fingerprints of ginseng stem and leaf saponin reference substances and spiked plasma sample by LC-ESI/MS and its application to analyzing the compounds absorbed into blood after oral administration of ginseng stem and leaf saponin in rat.
Biological & pharmaceutical bulletin 2007;30(9):1657-62.
2007: Bei Yan; Guangji Wang; Jianguo Sun; Xiaoyu Li; Yuanting Zheng; Hua Ai; Hua Lv; Xiaoming Wu; Jinyi Xu
Identification of the major metabolites of 5-n-butyl-4-{4-[2-(1H-tetrazole-5-yl)-1H-pyrrol-1-yl]phenylmethyl}-2,4-dihydro-2-(2,6-dichloridephenyl)-3H-1,2,4-triazol-3-one, a new angiotensin type 1 receptor antagonist, in rat bile by HPLC-diode array detection-MS and HPLC-MS/MS.
Biomedical chromatography : BMC 2007;21(9):912-24.
2007: Hui He; Ying Zhao; Xijing Chen; Yuanting Zheng; Xiaolan Wu; Rui Wang; Tingting Li; Qiangling Yu; Jing Jing; Le Ma; Weichao Ren; Deen Han; Guangji Wang
Quantitative determination of trans-polydatin, a natural strong anti-oxidative compound, in rat plasma and cellular environment of a human colon adenocarcinoma cell line for pharmacokinetic studies.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;855(2):145-51.
2007: Xijing Chen; Jing Jing; Weichao Ren; De-En Han; Ning Jing; Guangji Wang
Determination of 5-aminoimidazole-4-carboxamide in human plasma by ion-pair extraction and LC-MS/MS.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;855(2):140-4.
2007: Shu-Feng Zhou; Charlie Changli Xue; Xue-Qing Yu; Guangji Wang
Metabolic activation of herbal and dietary constituents and its clinical and toxicological implications: an update.
Current drug metabolism 2007;8(6):526-53.
2007: Jing Jing; Weichao Ren; Xijing Chen; Hui He; Wei Zhou; Xuping Zhu; Ya Sun; Guangji Wang
Determination and pharmacokinetics of manidipine in human plasma by HPLC/ESIMS.
Biomedical chromatography : BMC 2007;21(8):836-40.
2007: Qi Zhang; Guangji Wang; Yu Du; Lingling Zhu; A Jiye
GC/MS analysis of the rat urine for metabonomic research.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;854(1-2):20-5.
2007: Xiaoyu Li; Jianguo Sun; Guangji Wang; Haiping Hao; Yan Liang; Yuanting Zheng; Bei Yan; Longsheng Sheng
Simultaneous determination of panax notoginsenoside R1, ginsenoside Rg1, Rd, Re and Rb1 in rat plasma by HPLC/ESI/MS: platform for the pharmacokinetic evaluation of total panax notoginsenoside, a typical kind of multiple constituent traditional Chinese medicine.
Biomedical chromatography : BMC 2007;21(7):735-46.
2007: Xiaoyu Li; Guangji Wang; Jianguo Sun; Haiping Hao; Yuqing Xiong; Bei Yan; Yuanting Zheng; Longsheng Sheng
Pharmacokinetic and absolute bioavailability study of total panax notoginsenoside, a typical multiple constituent traditional chinese medicine (TCM) in rats.
Biological & pharmaceutical bulletin 2007;30(5):847-51.
2007: Feng Shao; Jianguo Sun; Guangji Wang; Haitang Xie; Xiaoyan Zhu; Jingwei Zhang
Liquid chromatographic-mass spectrometry analysis and pharmacokinetic studies of a novel rabeprazole formulation, sterile powder for injection, in dogs and rats.
Biopharmaceutics & drug disposition 2007;28(4):177-86.
2007: HaiYan Liu; DongMei Zhang; Xiao Xu; XiaoDong Liu; Guangji Wang; Lin Xie; XiaoYan Pang; Li Liu
Attenuated function and expression of P-glycoprotein at blood-brain barrier and increased brain distribution of phenobarbital in streptozotocin-induced diabetic mice.
European journal of pharmacology 2007;561(1-3):226-32.
2007: Tong Lu; Jue Song; Fang Huang; Yuanxiong Deng; Lin Xie; Guangji Wang; Xiaodong Liu
Comparative pharmacokinetics of baicalin after oral administration of pure baicalin, Radix scutellariae extract and Huang-Lian-Jie-Du-Tang to rats.
Journal of ethnopharmacology 2007;110(3):412-8.
2007: Feng Shao; Guangji Wang; Haitang Xie; Xiaoyan Zhu; Jianguo Sun; Jiye A
Pharmacokinetic study of triptolide, a constituent of immunosuppressive chinese herb medicine, in rats.
Biological & pharmaceutical bulletin 2007;30(4):702-7.
2007: Xijing Chen; Hui He; Guangji Wang; Bing Yang; Weichao Ren; Le Ma; Qiaoling Yu
Stereospecific determination of cis- and trans-resveratrol in rat plasma by HPLC: application to pharmacokinetic studies.
Biomedical chromatography : BMC 2007;21(3):257-65.
2007: Xiaoyu Li; Jianguo Sun; Guangji Wang; Yuanting Zheng; Bei Yan; Haitang Xie; Yi Gu; Hongchan Ren
Determination of secnidazole in human plasma by high-performance liquid chromatography with UV detection and its application to the bioequivalence studies.
Biomedical chromatography : BMC 2007;21(3):304-9.
2007: Yuanwei Jia; Guangji Wang; Haitang Xie; Xiaochang Dai; Yanhua Wang; Wei Wang; Meijuan Xu; Rui Wang; Chen Yao
Quantitative determination of helicid in rat plasma by liquid chromatography-electrospray ionization mass spectrometry and its application to preliminary pharmacokinetic studies.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;847(2):72-7.
2007: Haiping Hao; Guangji Wang; Nan Cui; Jing Li; Lin Xie; Zuoqi Ding
Identification of a novel intestinal first pass metabolic pathway: NQO1 mediated quinone reduction and subsequent glucuronidation.
Current drug metabolism 2007;8(2):137-49.
2007: Yuanting Zheng; Guangji Wang; Xiaolan Wu; Jianguo Sun; Xiaoyu Li; Yi Gu; Hua Lv; Yan Liang; Bei Yan; Wencai Ye
Quantitative analysis of 23-hydroxybetulinic acid, a novel anticancer substance, in the cellular environment of a human colon adenocarcinoma cell line for cellular pharmacokinetic studies.
Rapid communications in mass spectrometry : RCM 2007;21(5):779-86.
2006: Yongsheng Wang; Xiaoping Zhao; Jiao Zhong; Yan Chen; Xiaoquan Liu; Guangji Wang
Simple determination of pirfenidone in rat plasma via high-performance liquid chromatography.
Biomedical chromatography : BMC 2006;20(12):1375-9.
2006: Haiping Hao; Guangji Wang; Nan Cui; Jing Li; Lin Xie; Zuoqi Ding
Pharmacokinetics, absorption and tissue distribution of tanshinone IIA solid dispersion.
Planta medica 2006;72(14):1311-7.
2006: Yan Chen; Xiao Quan Liu; Jiao Zhong; Xiaoping Zhao; Yongsheng Wang; Guangji Wang
Stereoselective pharmacokinetics of ornidazole after intravenous administration of individual enantiomers and the racemate.
Chirality 2006;18(10):799-802.
2006: Xijing Chen; Bing Yang; Liang Ni; Guangji Wang
Simultaneous analysis of thiamphenicol and its prodrug thiamphenicol glycinate in human plasma and urine by high performance liquid chromatography: application to pharmacokinetic study.
Journal of pharmaceutical and biomedical analysis 2006;41(3):943-9.
2006: Xiaoping Zhao; Xiaoquan Liu; Yongsheng Wang; Jiao Zhong; Yan Chen; Guangji Wang
Determination of vinflunine in rat plasma by liquid chromatography-electrospray ionization mass spectrometry for a pharmacokinetic study.
Journal of pharmaceutical and biomedical analysis 2006;41(3):906-11.
2006: Ruian Xu; Phillip Harrison; Miao Chen; Linyan Li; Tung Yu Tsui; Peter C W Fung; Pik-To Cheung; Guangji Wang; Hua Li; Yong Diao; Geoffrey W Krissansen; Sue Xu; Farzin Farzaneh
Cytoglobin overexpression protects against damage-induced fibrosis.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;13(6):1093-100.
2006: Feng Shao; Guangji Wang; Jianguo Sun; Haitang Xie; Hao Li; Yan Liang; Rong Zhang; Xiaoyan Zhu
Liquid chromatographic/mass spectrometry assay of triptolide in dog plasma and its application to pharmacokinetic study.
Journal of pharmaceutical and biomedical analysis 2006;41(2):341-6.
2006: Yi Gu; Guangji Wang; Jianguo Sun; Yuanwei Jia; Meijuan Xu; Wei Wang
In vitro assessment of plasma protein binding of 20(R)-ginsenoside Rh2 by equilibrium dialysis and LC-MS analysis: a case of species differences.
Biological & pharmaceutical bulletin 2006;29(5):951-6.
2006: Hui He; Xijing Chen; Guangji Wang; Jiping Wang; Andrew K Davey
High-performance liquid chromatography spectrometric analysis of trans-resveratrol in rat plasma.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2006;832(2):177-80.
2006: Yi Gu; Guangji Wang; Jianguo Sun
Simultaneous determination of erythromycin ethylsuccinate and its metabolite erythromycin in human plasma using liquid chromatography-electrospray ionization mass spectrometry for clinical study.
Journal of pharmaceutical and biomedical analysis 2006;40(3):737-43.
2006: Chenrong Huang; Guangji Wang; Hao Li; Haitang Xie; Jianguo Sun; Hua Lv; Tian Lv
Sensitive and selective liquid chromatography-electrospray ionisation-mass spectrometry analysis of astragaloside-IV in rat plasma.
Journal of pharmaceutical and biomedical analysis 2006;40(3):788-93.
2006: Haiping Hao; Guangji Wang; Peng Li; Jing Li; Zuoqi Ding
Simultaneous quantification of cryptotanshinone and its active metabolite tanshinone IIA in plasma by liquid chromatography/tandem mass spectrometry (LC-MS/MS).
Journal of pharmaceutical and biomedical analysis 2006;40(2):382-8.
2006: Rui Wang; Guangji Wang; Haiping Hao; HaiTang Xie; Jinfeng Zhang; Feng Wu
Quantitative determination of atractylenolide III in rat plasma by liquid chromatography electrospray ionization mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2006;831(1-2):36-41.
2006: Xiaoyu Li; Guangji Wang; Haitang Xie; Rui Wang; Meijuan Xu; Wei Wang; Jining Tao; Jianguo Sun
Simultaneous determination of MHD and DMD in dog plasma by high-performance liquid chromatography with fluorescence detection and its application to pharmacokinetic studies.
Analytical and bioanalytical chemistry 2006;384(4):958-63.
2006: Bin Guo; Chuan Li; Guangji Wang; Laishun Chen
Rapid and direct measurement of free concentrations of highly protein-bound fluoxetine and its metabolite norfluoxetine in plasma.
Rapid communications in mass spectrometry : RCM 2006;20(1):39-47.
2005: Meijuan Xu; Guangji Wang; Haitang Xie; Rui Wang; Wei Wang; Xiaoyu Li; Hao Li; Danni Zhu; Lei Yue
Determination of schizandrin in rat plasma by high-performance liquid chromatography-mass spectrometry and its application in rat pharmacokinetic studies.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005;828(1-2):55-61.
2005: Jing Li; Guangji Wang; Peng Li; Haiping Hao
Simultaneous determination of tanshinone IIA and cryptotanshinone in rat plasma by liquid chromatography-electrospray ionisation-mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005;826(1-2):26-30.
2005: Jianguo Sun; Guangji Wang; Wei Wang; Shuai Zhao; Yi Gu; Jinwen Zhang; Mingwen Huang; Feng Shao; Hao Li; Qi Zhang; Haitang Xie
Simultaneous determination of loratadine and pseudoephedrine sulfate in human plasma by liquid chromatography-electrospray mass spectrometry for pharmacokinetic studies.
Journal of pharmaceutical and biomedical analysis 2005;39(1-2):217-24.
2005: Xiaotian Li; Guangji Wang; Sujun Wang; Jianguo Sun; Jinghan Liu
Pharmacokinetics of guanfu base I, an active metabolite of guanfu base A, in rats.
Biological & pharmaceutical bulletin 2005;28(8):1363-5.
2005: Jianguo Sun; Guangji Wang; Xie Haitang; Li Hao; Pan Guoyu; Ian Tucker
Simultaneous rapid quantification of ginsenoside Rg1 and its secondary glycoside Rh1 and aglycone protopanaxatriol in rat plasma by liquid chromatography-mass spectrometry after solid-phase extraction.
Journal of pharmaceutical and biomedical analysis 2005;38(1):126-32.
2005: Haiping Hao; Guangji Wang; Jianguo Sun; Zuoqi Ding; Xiaolan Wu; Michael Roberts
Unidirectional inversion of ibuprofen in Caco-2 cells: developing a suitable model for presystemic chiral inversion study.
Biological & pharmaceutical bulletin 2005;28(4):682-7.
2005: Sujun Wang; Guangji Wang; Xiaotian Li; Jianguo Sun; Renling Ma; Longsheng Sheng
Simultaneous determination of oxymatrine and its active metabolite matrine in dog plasma by liquid chromatography-mass spectrometry and its application to pharmacokinetic studies.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005;817(2):319-25.
2005: Haiping Hao; Guangji Wang; Jianguo Sun
Enantioselective pharmacokinetics of ibuprofen and involved mechanisms.
Drug metabolism reviews 2005;37(1):215-34.
2004: Yongchuan Gu; Guangji Wang; Guoyu Pan; J Paul Fawcett; Jiye A; Jianguo Sun
Transport and bioavailability studies of astragaloside IV, an active ingredient in Radix Astragali.
Basic & clinical pharmacology & toxicology 2004;95(6):295-8.
2004: Yongchuan Gu; Guangji Wang; J Paul Fawcett
Determination of Astragaloside IV in rat plasma by liquid chromatography electrospray ionization mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2004;801(2):285-8.
2004: Xinghao Yang; Guangji Wang; Xiaotong Zhang
Release kinetics of catechins from chewing gum.
Journal of pharmaceutical sciences 2004;93(2):293-9.