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Gene-Jack Wang

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Michael Michaelides; Michael L Miller; Lisa Robison; Mike Subrize; Yasmin L Hurd; Ronald Kim; Nora D Volkow; Gene-Jack Wang; Panayotis K Thanos
Limbic activation to novel versus familiar food cues predicts food preference and alcohol intake.
Nora D Volkow; Gene-Jack Wang; Dardo Tomasi; Ruben Baler
The addictive dimensionality of obesity.
Panayotis K Thanos; Michael Michaelides; John K Robinson; Lisa S Robison; Gene-Jack Wang; Nora D Volkow
Obese rats with deficient leptin signaling exhibit heightened sensitivity to olfactory food cues.

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2013: Michael Michaelides; Michael L Miller; Lisa Robison; Mike Subrize; Yasmin L Hurd; Ronald Kim; Nora D Volkow; Gene-Jack Wang; Panayotis K Thanos
Limbic activation to novel versus familiar food cues predicts food preference and alcohol intake.
Brain research 2013;1512():37-44.
2013: Nora D Volkow; Gene-Jack Wang; Dardo Tomasi; Ruben Baler
The addictive dimensionality of obesity.
Biological psychiatry 2013;73(9):811-8.
2013: Panayotis K Thanos; Michael Michaelides; John K Robinson; Lisa S Robison; Gene-Jack Wang; Nora D Volkow
Obese rats with deficient leptin signaling exhibit heightened sensitivity to olfactory food cues.
Synapse (New York, N.Y.) 2013;67(4):171-8.
2013: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Jean Logan; L Jayne Maynard; Frank Telang; Dardo Tomasi; Christopher T Wong
Predominance of D2 receptors in mediating dopamine's effects in brain metabolism: effects of alcoholism.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013;33(10):4527-35.
2013: Panayotis K Thanos; Andrew Tucci; Gene-Jack Wang; Brenda J Anderson; Gary Heyman; John K Robinson; Lisa S Robison; Joshua Stamos; Nora D Volkow
Daily treadmill exercise attenuates cocaine cue-induced reinstatement and cocaine induced locomotor response but increases cocaine-primed reinstatement.
Behavioural brain research 2013;239():8-14.
2013: Foteini Delis; David K Grandy; Christina Rombola; Lauren Rosko; Panayotis K Thanos; Gene-Jack Wang; Nora D Volkow
Chronic mild stress increases alcohol intake in mice with low dopamine D2 receptor levels.
Behavioral neuroscience 2013;127(1):95-105.
2013: Deborah L Grady; David K Grandy; Claudia H Kawas; Alexandra G Moyzis; Jeffrey C Barnett; Chuansheng Chen; Valentina Ciobanu; Maria Corrada; Qi Dong; Anthony Napoli; Marcelo Rubinstein; Diana Shustarovich; Panayotis K Thanos; Nora D Volkow; Eric Wang; Gene-Jack Wang; Robert K Moyzis
DRD4 genotype predicts longevity in mouse and human.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013;33(1):286-91.
2013: Nora D Volkow; Gene-Jack Wang; Christopher Wong; David Alexoff; Helene Benveniste; Joanna S Fowler; Sung Won Kim; Jean Logan; Lisa Muench; Colleen Shea; Frank Telang; Dardo Tomasi
Acute alcohol intoxication decreases glucose metabolism but increases acetate uptake in the human brain.
NeuroImage 2013;64():277-83.
2012: Panayotis K Thanos; Nora D Volkow; Gene-Jack Wang; Mike Subrize; Mingjie Sun; Robert N Cooney; Derek Culnan; Foteini Delis; Andras Hajnal
Gastric bypass increases ethanol and water consumption in diet-induced obese rats.
Obesity surgery 2012;22(12):1884-92.
2012: Loai Alzghoul; Marco Bortolato; Kevin Chen; Ryan D Darling; Foteini Delis; Sean C Godar; Samuel Grant; Rick C S Lin; Kimberly L Simpson; Panayotis K Thanos; Nora D Volkow; Gene-Jack Wang; Junlin Zhang; Jean C Shih
Altered cerebellar organization and function in monoamine oxidase A hypomorphic mice.
Neuropharmacology 2012;63(7):1208-17.
2012: Muhammad A Parvaz; Nancy K Squires; Frank Telang; Nora D Volkow; Gene-Jack Wang; Patricia A Woicik; Nelly Alia-Klein; Thomas Maloney; Scott J Moeller; Rita Z Goldstein
Sensitivity to monetary reward is most severely compromised in recently abstaining cocaine addicted individuals: a cross-sectional ERP study.
Psychiatry research 2012;203(1):75-82.
2012: Nicole M Avena; Ashley N Gearhardt; Mark S Gold; Gene-Jack Wang; Marc N Potenza
Tossing the baby out with the bathwater after a brief rinse? The potential downside of dismissing food addiction based on limited data.
Nature reviews. Neuroscience 2012;13(7):514; author reply 514.
2012: Michael Michaelides; Panayotis K Thanos; Nora D Volkow; Gene-Jack Wang
Dopamine-related frontostriatal abnormalities in obesity and binge-eating disorder: emerging evidence for developmental psychopathology.
International review of psychiatry (Abingdon, England) 2012;24(3):211-8.
2012: Nora D Volkow; Gene-Jack Wang; Helene Benveniste; Joanna S Fowler; Ron Kim; Jean Logan; Frank Telang; Panayotis K Thanos; Dardo Tomasi; Sergi Ferré
Evidence that sleep deprivation downregulates dopamine D2R in ventral striatum in the human brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(19):6711-7.
2012: John Xie; Lindy Yow; Gene-Jack Wang; James D Weiland; Carlos J Cela; Elona Dhrami-Gavazi; Mark S Humayun; Hossein Jadvar; Gianluca Lazzi; Stephen H Tsang
Preservation of retinotopic map in retinal degeneration.
Experimental eye research 2012;98():88-96.
2012: Foteini Delis; David Grandy; Nora D Volkow; Gene-Jack Wang; Michalis Xenos; Helene Benveniste; Panayotis K Thanos
Loss of dopamine D2 receptors induces atrophy in the temporal and parietal cortices and the caudal thalamus of ethanol-consuming mice.
Alcoholism, clinical and experimental research 2012;36(5):815-25.
2012: Nora D Volkow; Gene-Jack Wang; Tim L Wigal; Christopher T Wong; Joanna S Fowler; Scott H Kollins; Jean Logan; Jeffrey H Newcorn; Frank Telang; Dardo Tomasi; James M Swanson
Methylphenidate-elicited dopamine increases in ventral striatum are associated with long-term symptom improvement in adults with attention deficit hyperactivity disorder.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(3):841-9.
2012: Michael Michaelides; Panayotis K Thanos; Mala Ananth; Jacob Cho; Ronald Kim; Gene-Jack Wang; Nora D Volkow
PET imaging predicts future body weight and cocaine preference.
NeuroImage 2012;59(2):1508-13.
2012: Michael Michaelides; Panayotis K Thanos; Nora D Volkow; Gene-Jack Wang
Translational neuroimaging in drug addiction and obesity.
ILAR journal / National Research Council, Institute of Laboratory Animal Resources 2012;53(1):59-68.
2012: Elena Shumay; Gene-Jack Wang; Christopher Wong; Nelly Alia-Klein; Joanna S Fowler; Rita Z Goldstein; Jean Logan; Tom Maloney; Nora D Volkow
Repeat variation in the human PER2 gene as a new genetic marker associated with cocaine addiction and brain dopamine D2 receptor availability.
Translational psychiatry 2012;2():e86.
2011: Nora D Volkow; Gene-Jack Wang; T L Wigal; Christopher Wong; Joanna S Fowler; Rita Z Goldstein; N Klein; S H Kollins; Jean Logan; Jeffrey H Newcorn; Frank Telang; J M Swanson
Motivation deficit in ADHD is associated with dysfunction of the dopamine reward pathway.
Molecular psychiatry 2011;16(11):1147-54.
2011: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Dardo Tomasi; Frank Telang
Addiction: beyond dopamine reward circuitry.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(37):15037-42.
2011: Panayotis K Thanos; Carlos Bermeo; Gene-Jack Wang; Nora D Volkow
D-cycloserine facilitates extinction of cocaine self-administration in rats.
Synapse (New York, N.Y.) 2011;65(9):938-44.
2011: Gene-Jack Wang; Christopher T Wong; Wei Zhu; Kochavi Galanti; Allan Geliebter; Hao Han; Millard C Jayne; Jean Logan; Peter A Selig; Frank W Telang; Nora D Volkow; Joanna S Fowler
Enhanced striatal dopamine release during food stimulation in binge eating disorder.
Obesity (Silver Spring, Md.) 2011;19(8):1601-8.
2011: John Xie; Lindy Yow; Mark S Humayun; Carlos J Cela; Gianluca Lazzi; Gene-Jack Wang; James David Weiland; Hossein Jadvar
Modeling and percept of transcorneal electrical stimulation in humans.
IEEE transactions on bio-medical engineering 2011;58(7):1932-9.
2011: Patricia A Woicik; Catherine Urban; Nelly Alia-Klein; Ashley Henry; Tom Maloney; Frank Telang; Gene-Jack Wang; Nora D Volkow; Rita Z Goldstein
A pattern of perseveration in cocaine addiction may reveal neurocognitive processes implicit in the Wisconsin Card Sorting Test.
Neuropsychologia 2011;49(7):1660-9.
2011: Jonathan P Dunning; Muhammad A Parvaz; Greg Hajcak; Tom Maloney; Nelly Alia-Klein; Patricia A Woicik; Frank Telang; Gene-Jack Wang; Nora D Volkow; Rita Z Goldstein
Motivated attention to cocaine and emotional cues in abstinent and current cocaine users--an ERP study.
The European journal of neuroscience 2011;33(9):1716-23.
2011: Nelly Alia-Klein; Muhammad A Parvaz; Patricia A Woicik; Anna B Konova; Tom Maloney; Elena Shumay; Ruiliang Wang; Frank Telang; Anat Biegon; Gene-Jack Wang; Joanna S Fowler; Dardo Tomasi; Nora D Volkow; Rita Z Goldstein
Gene x disease interaction on orbitofrontal gray matter in cocaine addiction.
Archives of general psychiatry 2011;68(3):283-94.
2011: Nora D Volkow; Dardo Tomasi; Gene-Jack Wang; Paul Vaska; Joanna S Fowler; Frank Telang; David Alexoff; Jean Logan; Christopher Wong
Effects of cell phone radiofrequency signal exposure on brain glucose metabolism.
JAMA : the journal of the American Medical Association 2011;305(8):808-13.
2011: Dardo Tomasi; Nora D Volkow; Gene-Jack Wang; R Wang; Frank Telang; E C Caparelli; Christopher Wong; Millard Jayne; Joanna S Fowler
Methylphenidate enhances brain activation and deactivation responses to visual attention and working memory tasks in healthy controls.
NeuroImage 2011;54(4):3101-10.
2011: Panayotis K Thanos; Jacob Cho; Ronald Kim; Michael Michaelides; Stefany Primeaux; George Bray; Gene-Jack Wang; Nora D Volkow
Bromocriptine increased operant responding for high fat food but decreased chow intake in both obesity-prone and resistant rats.
Behavioural brain research 2011;217(1):165-70.
2011: Nora D Volkow; Dardo Tomasi; Gene-Jack Wang; Joanna S Fowler; Frank Telang; Rita Z Goldstein; Nelly Alia-Klein; Christopher Wong
Reduced metabolism in brain "control networks" following cocaine-cues exposure in female cocaine abusers.
PloS one 2011;6(2):e16573.
2011: Nora D Volkow; Gene-Jack Wang; Ruben Baler
Reward, dopamine and the control of food intake: implications for obesity.
Trends in cognitive sciences 2011;15(1):37-46.
2011: Panayotis K Thanos; Vanessa Gopez; Foteini Delis; Michael Michaelides; David K Grandy; Gene-Jack Wang; George Kunos; Nora D Volkow
Upregulation of cannabinoid type 1 receptors in dopamine D2 receptor knockout mice is reversed by chronic forced ethanol consumption.
Alcoholism, clinical and experimental research 2011;35(1):19-27.
2010: Panayotis K Thanos; Andrew Tucci; Joshua Stamos; Lisa Robison; Gene-Jack Wang; Brenda J Anderson; Nora D Volkow
Chronic forced exercise during adolescence decreases cocaine conditioned place preference in Lewis rats.
Behavioural brain research 2010;215(1):77-82.
2010: Panayotis K Thanos; Ronald Kim; Jacob Cho; Michael Michaelides; Brenda J Anderson; Stefany D Primeaux; George A Bray; Gene-Jack Wang; John K Robinson; Nora D Volkow
Obesity-resistant S5B rats showed greater cocaine conditioned place preference than the obesity-prone OM rats.
Physiology & behavior 2010;101(5):713-8.
2010: Anat Biegon; Sung Won Kim; David Alexoff; Millard Jayne; Pauline Carter; Barbara Hubbard; Payton King; Jean Logan; Lisa Muench; Deborah Pareto; David Schlyer; Colleen Shea; Frank Telang; Gene-Jack Wang; Youwen Xu; Joanna S Fowler
Unique distribution of aromatase in the human brain: in vivo studies with PET and [N-methyl-11C]vorozole.
Synapse (New York, N.Y.) 2010;64(11):801-7.
2010: Rita Z Goldstein; Patricia A Woicik; Tom Maloney; Dardo Tomasi; Nelly Alia-Klein; Juntian Shan; Jean Honorio; Dimitris Samaras; Ruiliang Wang; Frank Telang; Gene-Jack Wang; Nora D Volkow
Oral methylphenidate normalizes cingulate activity in cocaine addiction during a salient cognitive task.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(38):16667-72.
2010: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Dardo Tomasi; Frank Telang; Ruben Baler
Addiction: decreased reward sensitivity and increased expectation sensitivity conspire to overwhelm the brain's control circuit.
BioEssays : news and reviews in molecular, cellular and developmental biology 2010;32(9):748-55.
2010: Michael Michaelides; Javier Pascau; Gispert Juan; Foteini Delis; David K Grandy; Gene-Jack Wang; Manuel Desco; Marcelo Rubinstein; Nora D Volkow; Panayotis K Thanos
Dopamine D4 receptors modulate brain metabolic activity in the prefrontal cortex and cerebellum at rest and in response to methylphenidate.
The European journal of neuroscience 2010;32(4):668-76.
2010: Jennifer Pfaffly; Michael Michaelides; Gene-Jack Wang; Jeffrey Pessin; Nora D Volkow; Panayotis K Thanos
Leptin increases striatal dopamine D2 receptor binding in leptin-deficient obese (ob/ob) mice.
Synapse (New York, N.Y.) 2010;64(7):503-10.
2010: Nora D Volkow; Dardo Tomasi; Gene-Jack Wang; Joanna S Fowler; Frank Telang; Ruiliang Wang; Dave Alexoff; Jean Logan; Christopher Wong; Kith Pradhan; Elisabeth C Caparelli; Yeming Ma; Millard Jayne
Effects of low-field magnetic stimulation on brain glucose metabolism.
NeuroImage 2010;51(2):623-8.
2010: Scott J Moeller; Thomas Maloney; Muhammad A Parvaz; Nelly Alia-Klein; Patricia A Woicik; Frank Telang; Gene-Jack Wang; Nora D Volkow; Rita Z Goldstein
Impaired insight in cocaine addiction: laboratory evidence and effects on cocaine-seeking behaviour.
Brain : a journal of neurology 2010;133(Pt 5):1484-93.
2010: Samuel Asensio; Maria J Romero; Francisco J Romero; Christopher Wong; Nelly Alia-Klein; Dardo Tomasi; Gene-Jack Wang; Frank Telang; Nora D Volkow; Rita Z Goldstein
Striatal dopamine D2 receptor availability predicts the thalamic and medial prefrontal responses to reward in cocaine abusers three years later.
Synapse (New York, N.Y.) 2010;64(5):397-402.
2010: Ruiliang Wang; Gene-Jack Wang; Rita Z Goldstein; Elisabeth C Caparelli; Nora D Volkow; Joanna S Fowler; Dardo Tomasi
Induced magnetic force in human heads exposed to 4 T MRI.
Journal of magnetic resonance imaging : JMRI 2010;31(4):815-20.
2010: Panayotis K Thanos; Rahila Habibi; Michael Michaelides; Ujval B Patel; Katherine Suchland; Brenda J Anderson; John K Robinson; Gene-Jack Wang; David K Grandy; Nora D Volkow
Dopamine D4 receptor (D4R) deletion in mice does not affect operant responding for food or cocaine.
Behavioural brain research 2010;207(2):508-11.
2010: Nora D Volkow; Joanna S Fowler; Gene-Jack Wang; Frank Telang; Jean Logan; Millard Jayne; Yeming Ma; Kith Pradhan; Christopher Wong; James M Swanson
Cognitive control of drug craving inhibits brain reward regions in cocaine abusers.
NeuroImage 2010;49(3):2536-43.
2010: Joanna S Fowler; Jean Logan; Albert J Azzaro; Robert M Fielding; Wei Zhu; Amy K Poshusta; Daniel Burch; Barry Brand; James Free; Mahnaz Asgharnejad; Gene-Jack Wang; Frank Telang; Barbara Hubbard; Millard Jayne; Payton King; Pauline Carter; Scott Carter; Youwen Xu; Colleen Shea; Lisa Muench; David Alexoff; Elena Shumay; Michael Schueller; Donald Warner; Karen Apelskog-Torres
Reversible inhibitors of monoamine oxidase-A (RIMAs): robust, reversible inhibition of human brain MAO-A by CX157.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2010;35(3):623-31.
2010: Rita Z Goldstein; P A Woicik; S J Moeller; F Telang; Millard Jayne; C Wong; Gene-Jack Wang; Joanna S Fowler; Nora D Volkow
Liking and wanting of drug and non-drug rewards in active cocaine users: the STRAP-R questionnaire.
Journal of psychopharmacology (Oxford, England) 2010;24(2):257-66.
2010: Elisabeth C Caparelli; Rita Z Goldstein; David J Anschel; W Backus; Tom Maloney; Frank Telang; Gene-Jack Wang; F Henn
Simultaneous TMS-fMRI of the Visual Cortex Reveals Functional Network, Even in Absence of Phosphene Sensation.
The open neuroimaging journal 2010;4():100-10.
2010: Nora D Volkow; Joanna S Fowler; Gene-Jack Wang; Elena Shumay; Frank Telang; Peter K Thanos; David Alexoff
Distribution and pharmacokinetics of methamphetamine in the human body: clinical implications.
PloS one 2010;5(12):e15269.
2010: Nora D Volkow; Gene-Jack Wang; Dardo Tomasi; Frank Telang; Joanna S Fowler; Kith Pradhan; Millard Jayne; Jean Logan; Rita Z Goldstein; Nelly Alia-Klein; Christopher Wong
Methylphenidate attenuates limbic brain inhibition after cocaine-cues exposure in cocaine abusers.
PloS one 2010;5(7):e11509.
2010: Panayotis K Thanos; Iliyan Ivanov; John K Robinson; Michael Michaelides; Gene-Jack Wang; James M Swanson; Jeffrey H Newcorn; Nora D Volkow
Dissociation between spontaneously hypertensive (SHR) and Wistar-Kyoto (WKY) rats in baseline performance and methylphenidate response on measures of attention, impulsivity and hyperactivity in a Visual Stimulus Position Discrimination Task.
Pharmacology, biochemistry, and behavior 2010;94(3):374-9.
2009: Nora D Volkow; Gene-Jack Wang; Scott H Kollins; Tim L Wigal; Jeffrey H Newcorn; Frank Telang; Joanna S Fowler; Wei Zhu; Jean Logan; Yeming Ma; Kith Pradhan; Christopher Wong; James M Swanson
Evaluating dopamine reward pathway in ADHD: clinical implications.
JAMA : the journal of the American Medical Association 2009;302(10):1084-91.
2009: Scott J Moeller; Thomas Maloney; Muhammad A Parvaz; Jonathan P Dunning; Nelly Alia-Klein; Patricia A Woicik; Greg Hajcak; Frank Telang; Gene-Jack Wang; Nora D Volkow; Rita Z Goldstein
Enhanced choice for viewing cocaine pictures in cocaine addiction.
Biological psychiatry 2009;66(2):169-76.
2009: Nelly Alia-Klein; Rita Z Goldstein; Dardo Tomasi; Patricia A Woicik; Scott J Moeller; Benjamin Williams; Ian W Craig; Frank Telang; Anat Biegon; Gene-Jack Wang; Joanna S Fowler; Nora D Volkow
Neural mechanisms of anger regulation as a function of genetic risk for violence.
Emotion (Washington, D.C.) 2009;9(3):385-96.
2009: Panayotis K Thanos; Carlos Bermeo; Gene-Jack Wang; Nora D Volkow
D-cycloserine accelerates the extinction of cocaine-induced conditioned place preference in C57bL/c mice.
Behavioural brain research 2009;199(2):345-9.
2009: Nora D Volkow; Dardo Tomasi; Gene-Jack Wang; Frank Telang; Joanna S Fowler; Ruiliang L Wang; Jean Logan; Christopher Wong; Millard Jayne; James M Swanson
Hyperstimulation of striatal D2 receptors with sleep deprivation: Implications for cognitive impairment.
NeuroImage 2009;45(4):1232-40.
2009: Patricia A Woicik; Scott J Moeller; Nelly Alia-Klein; Tom Maloney; Tanya M Lukasik; Olga Yeliosof; Gene-Jack Wang; Nora D Volkow; Rita Z Goldstein
The neuropsychology of cocaine addiction: recent cocaine use masks impairment.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2009;34(5):1112-22.
2009: Nora D Volkow; Joanna S Fowler; Jean Logan; David Alexoff; Wei Zhu; Frank Telang; Gene-Jack Wang; Millard Jayne; Jacob M Hooker; Christopher Wong; Barbara Hubbard; Pauline Carter; Donald Warner; Payton King; Colleen Shea; Youwen Xu; Lisa Muench; Karen Apelskog-Torres
Effects of modafinil on dopamine and dopamine transporters in the male human brain: clinical implications.
JAMA : the journal of the American Medical Association 2009;301(11):1148-54.
2009: Gene-Jack Wang; Panayotis K Thanos; Nora D Volkow; Joanna S Fowler
Imaging of brain dopamine pathways: implications for understanding obesity.
Journal of addiction medicine 2009;3(1):8-18.
2009: Gene-Jack Wang; Nora D Volkow; Frank Telang; Millard Jayne; Yeming Ma; Kith Pradhan; Wei Zhu; Christopher T Wong; Panayotis K Thanos; Allan Geliebter; Anat Biegon; Joanna S Fowler
Evidence of gender differences in the ability to inhibit brain activation elicited by food stimulation.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(4):1249-54.
2009: Dardo Tomasi; Gene-Jack Wang; Ruiliang Wang; Walter Backus; Allan Geliebter; Frank Telang; Millar C Jayne; Christopher Wong; Joanna S Fowler; Nora D Volkow
Association of body mass and brain activation during gastric distention: implications for obesity.
PloS one 2009;4(8):e6847.
2009: Dardo Tomasi; Nora D Volkow; Ruiliang Wang; Frank Telang; Gene-Jack Wang; Linda Chang; Thomas Ernst; Joanna S Fowler
Dopamine transporters in striatum correlate with deactivation in the default mode network during visuospatial attention.
PloS one 2009;4(6):e6102.
2009: Lisa M Davis; Michael Michaelides; Lawrence J Cheskin; Timothy H Moran; Susan Aja; Paul A Watkins; Zhengtong Pei; Carlo Contoreggi; Karen McCullough; Bruce Hope; Gene-Jack Wang; Nora D Volkow; Panayotis K Thanos
Bromocriptine administration reduces hyperphagia and adiposity and differentially affects dopamine D2 receptor and transporter binding in leptin-receptor-deficient Zucker rats and rats with diet-induced obesity.
Neuroendocrinology 2009;89(2):152-62.
2008: Joanna S Fowler; Nora D Volkow; Jean Logan; David Alexoff; Frank Telang; Gene-Jack Wang; Christopher Wong; Yeming Ma; Aarti Kriplani; Kith Pradhan; David Schlyer; Millard Jayne; Barbara Hubbard; Pauline Carter; Donald Warner; Payton King; Colleen Shea; Youwen Xu; Lisa Muench; Karen Apelskog
Fast uptake and long-lasting binding of methamphetamine in the human brain: comparison with cocaine.
NeuroImage 2008;43(4):756-63.
2008: Nelly Alia-Klein; Aarti Kriplani; Kith Pradhan; Jim Yeming Ma; Jean Logan; Benjamin Williams; Ian W Craig; Frank Telang; Dardo Tomasi; Rita Z Goldstein; Gene-Jack Wang; Nora D Volkow; Joanna S Fowler
The MAO-A genotype does not modulate resting brain metabolism in adults.
Psychiatry research 2008;164(1):73-6.
2008: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Frank Telang
Overlapping neuronal circuits in addiction and obesity: evidence of systems pathology.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2008;363(1507):3191-200.
2008: Nora D Volkow; Gene-Jack Wang; Frank Telang; Joanna S Fowler; Panayotis K Thanos; Jean Logan; David Alexoff; Yu-Shin Ding; Christopher Wong; Yeming Ma; Kith Pradhan
Low dopamine striatal D2 receptors are associated with prefrontal metabolism in obese subjects: possible contributing factors.
NeuroImage 2008;42(4):1537-43.
2008: Panayotis K Thanos; Roberto C Ramalhete; Michael Michaelides; Yianni K Piyis; Gene-Jack Wang; Nora D Volkow
Leptin receptor deficiency is associated with upregulation of cannabinoid 1 receptors in limbic brain regions.
Synapse (New York, N.Y.) 2008;62(9):637-42.
2008: Rita Z Goldstein; Muhammad A Parvaz; Tom Maloney; Nelly Alia-Klein; Patricia A Woicik; Frank Telang; Gene-Jack Wang; Nora D Volkow
Compromised sensitivity to monetary reward in current cocaine users: an ERP study.
Psychophysiology 2008;45(5):705-13.
2008: Nora D Volkow; Gene-Jack Wang; Frank Telang; Joanna S Fowler; Jean Logan; Christopher Wong; Jim Ma; Kith Pradhan; Dardo Tomasi; Peter K Thanos; Sergi Ferré; Millard Jayne
Sleep deprivation decreases binding of [11C]raclopride to dopamine D2/D3 receptors in the human brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(34):8454-61.
2008: Linda Chang; Gene-Jack Wang; Nora D Volkow; Thomas Ernst; Frank Telang; Jean Logan; Joanna S Fowler
Decreased brain dopamine transporters are related to cognitive deficits in HIV patients with or without cocaine abuse.
NeuroImage 2008;42(2):869-78.
2008: Panayotis K Thanos; Michael Michaelides; Christopher W Ho; Gene-Jack Wang; Amy H Newman; Christian A Heidbreder; Charles R Ashby; Eliot L Gardner; Nora D Volkow
The effects of two highly selective dopamine D3 receptor antagonists (SB-277011A and NGB-2904) on food self-administration in a rodent model of obesity.
Pharmacology, biochemistry, and behavior 2008;89(4):499-507.
2008: Nelly Alia-Klein; Rita Z Goldstein; Aarti Kriplani; Jean Logan; Dardo Tomasi; Benjamin Williams; Frank Telang; Elena Shumay; Anat Biegon; Ian W Craig; Fritz Henn; Gene-Jack Wang; Nora D Volkow; Joanna S Fowler
Brain monoamine oxidase A activity predicts trait aggression.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(19):5099-104.
2008: Panayotis K Thanos; Michael Michaelides; Helene Benveniste; Gene-Jack Wang; Nora D Volkow
The effects of cocaine on regional brain glucose metabolism is attenuated in dopamine transporter knockout mice.
Synapse (New York, N.Y.) 2008;62(5):319-24.
2008: Nora D Volkow; Yeming Ma; Wei Zhu; Joanna S Fowler; Juan Li; Manlong Rao; Klaus Mueller; Kith Pradhan; Christopher Wong; Gene-Jack Wang
Moderate doses of alcohol disrupt the functional organization of the human brain.
Psychiatry research 2008;162(3):205-13.
2008: Gene-Jack Wang; Dardo Tomasi; Walter Backus; Ruiliang Wang; Frank Telang; Allan Geliebter; Judith Korner; Angela Bauman; Joanna S Fowler; Panayotis K Thanos; Nora D Volkow
Gastric distention activates satiety circuitry in the human brain.
NeuroImage 2008;39(4):1824-31.
2008: Nora D Volkow; Gene-Jack Wang; Frank Telang; Joanna S Fowler; Jean Logan; Anna Rose Childress; Millard Jayne; Yeming Ma; Christopher Wong
Dopamine increases in striatum do not elicit craving in cocaine abusers unless they are coupled with cocaine cues.
NeuroImage 2008;39(3):1266-73.
2008: Panayotis K Thanos; Gene-Jack Wang; Nora D Volkow
Positron emission tomography as a tool for studying alcohol abuse.
Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism 2008;31(3):233-7.
2008: Nora D Volkow; Joanna S Fowler; Gene-Jack Wang; Frank Telang; Jean Logan; Christopher Wong; Jim Ma; Kith Pradhan; Helene Benveniste; James M Swanson
Methylphenidate decreased the amount of glucose needed by the brain to perform a cognitive task.
PloS one 2008;3(4):e2017.
2008: Panayotis K Thanos; Michael Michaelides; Yiannis K Piyis; Gene-Jack Wang; Nora D Volkow
Food restriction markedly increases dopamine D2 receptor (D2R) in a rat model of obesity as assessed with in-vivo muPET imaging ([11C] raclopride) and in-vitro ([3H] spiperone) autoradiography.
Synapse (New York, N.Y.) 2008;62(1):50-61.
2008: Rachel Tomer; Rita Z Goldstein; Gene-Jack Wang; Christopher Wong; Nora D Volkow
Incentive motivation is associated with striatal dopamine asymmetry.
Biological psychology 2008;77(1):98-101.
2007: Nora D Volkow; Gene-Jack Wang; Frank Telang; Joanna S Fowler; Jean Logan; Millard Jayne; Yeming Ma; Kith Pradhan; Christopher Wong
Profound decreases in dopamine release in striatum in detoxified alcoholics: possible orbitofrontal involvement.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(46):12700-6.
2007: Nora D Volkow; Joanna S Fowler; Gene-Jack Wang; James M Swanson; Frank Telang
Dopamine in drug abuse and addiction: results of imaging studies and treatment implications.
Archives of neurology 2007;64(11):1575-9.
2007: Panayotis K Thanos; Michael Michaelides; Helene Benveniste; Gene-Jack Wang; Nora D Volkow
Effects of chronic oral methylphenidate on cocaine self-administration and striatal dopamine D2 receptors in rodents.
Pharmacology, biochemistry, and behavior 2007;87(4):426-33.
2007: Lisa Mosconi; Wai Hon Tsui; Henry Rusinek; Susan De Santi; Yi Li; Gene-Jack Wang; Alberto Pupi; Joanna S Fowler; Mony J de Leon
Quantitation, regional vulnerability, and kinetic modeling of brain glucose metabolism in mild Alzheimer's disease.
European journal of nuclear medicine and molecular imaging 2007;34(9):1467-79.
2007: Joanna S Fowler; Nelly Alia-Klein; Aarti Kriplani; Jean Logan; Benjamin Williams; Wei Zhu; Ian W Craig; Frank Telang; Rita Goldstein; Nora D Volkow; Paul Vaska; Gene-Jack Wang
Evidence that brain MAO A activity does not correspond to MAO A genotype in healthy male subjects.
Biological psychiatry 2007;62(4):355-8.
2007: Jean Logan; Gene-Jack Wang; Frank Telang; Joanna S Fowler; David Alexoff; John Zabroski; Millard Jayne; Barbara Hubbard; Payton King; Pauline Carter; Colleen Shea; Youwen Xu; Lisa Muench; David Schlyer; Susan Learned-Coughlin; Valerie Cosson; Nora D Volkow; Yu-Shin Ding
Imaging the norepinephrine transporter in humans with (S,S)-[11C]O-methyl reboxetine and PET: problems and progress.
Nuclear medicine and biology 2007;34(6):667-79.
2007: Nelly Alia-Klein; Rita Z Goldstein; Dardo Tomasi; Lei Zhang; Stephanie Fagin Jones; Frank Telang; Gene-Jack Wang; Joanna S Fowler; Nora D Volkow
What is in a word? No versus Yes differentially engage the lateral orbitofrontal cortex.
Emotion (Washington, D.C.) 2007;7(3):649-59.
2007: Nora D Volkow; Gene-Jack Wang; Jeffrey H Newcorn; Frank Telang; Mary Solanto; Joanna S Fowler; Jean Logan; Yeming Ma; Kurt Schulz; Kith Pradhan; Christopher Wong; James M Swanson
Depressed dopamine activity in caudate and preliminary evidence of limbic involvement in adults with attention-deficit/hyperactivity disorder.
Archives of general psychiatry 2007;64(8):932-40.
2007: Nora D Volkow; Gene-Jack Wang; Jeffrey H Newcorn; Joanna S Fowler; Frank Telang; Mary Solanto; Jean Logan; Christopher Wong; Yeming Ma; James M Swanson; Kurt Schulz; Kith Pradhan
Brain dopamine transporter levels in treatment and drug naïve adults with ADHD.
NeuroImage 2007;34(3):1182-90.
2007: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Frank Telang; Millard Jayne; Christopher Wong
Stimulant-induced enhanced sexual desire as a potential contributing factor in HIV transmission.
The American journal of psychiatry 2007;164(1):157-60.
2006: Gene-Jack Wang; Julia Yang; Nora D Volkow; Frank Telang; Yeming Ma; Wei Zhu; Christopher T Wong; Dardo Tomasi; Panayotis K Thanos; Joanna S Fowler
Gastric stimulation in obese subjects activates the hippocampus and other regions involved in brain reward circuitry.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(42):15641-5.
2006: Nora D Volkow; Gene-Jack Wang; Yeming Ma; Joanna S Fowler; Christopher Wong; Millard Jayne; Frank Telang; James M Swanson
Effects of expectation on the brain metabolic responses to methylphenidate and to its placebo in non-drug abusing subjects.
NeuroImage 2006;32(4):1782-92.
2006: Nora D Volkow; Gene-Jack Wang; Henri Begleiter; Bernice Porjesz; Joanna S Fowler; Frank Telang; Christopher Wong; Yeming Ma; Jean Logan; Rita Goldstein; David Alexoff; Panayotis K Thanos
High levels of dopamine D2 receptors in unaffected members of alcoholic families: possible protective factors.
Archives of general psychiatry 2006;63(9):999-1008.
2006: Tomas Drgon; Zhicheng Lin; Gene-Jack Wang; Joanna S Fowler; John Pablo; Deborah C Mash; Nora D Volkow; George R. Uhl
Common human 5' dopamine transporter (SLC6A3) haplotypes yield varying expression levels in vivo.
Cellular and molecular neurobiology 2006;26(4-6):875-89.
2006: Nora D Volkow; Gene-Jack Wang; Frank Telang; Joanna S Fowler; Jean Logan; Anna Rose Childress; Millard Jayne; Yeming Ma; Christopher Wong
Cocaine cues and dopamine in dorsal striatum: mechanism of craving in cocaine addiction.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(24):6583-8.
2006: Nora D Volkow; Gene-Jack Wang; Dinko Franceschi; Joanna S Fowler; Panayotis Peter K Thanos; Laurence Maynard; S John Gatley; Christopher Wong; Richard L Veech; George Kunos; Ting Kai Li
Low doses of alcohol substantially decrease glucose metabolism in the human brain.
NeuroImage 2006;29(1):295-301.
2005: Joanna S Fowler; Jean Logan; Nora D Volkow; Gene-Jack Wang
Translational neuroimaging: positron emission tomography studies of monoamine oxidase.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2005;7(6):377-87.
2005: Joanna S Fowler; Jean Logan; Gene-Jack Wang; Nora D Volkow; Frank Telang; Wei Zhu; Dinko Franceschi; Colleen Shea; Victor Garza; Youwen Xu; Yu-Shin Ding; David Alexoff; Donald Warner; Noelwah Netusil; Pauline Carter; Millard Jayne; Payton King; Paul Vaska
Comparison of monoamine oxidase a in peripheral organs in nonsmokers and smokers.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2005;46(9):1414-20.
2005: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Yu-Shin Ding
Imaging the effects of methylphenidate on brain dopamine: new model on its therapeutic actions for attention-deficit/hyperactivity disorder.
Biological psychiatry 2005;57(11):1410-5.
2005: Panayotis K Thanos; Seth N Rivera; Katrina Weaver; David K Grandy; Marcelo Rubinstein; Hiroyuki Umegaki; Gene-Jack Wang; Robert Hitzemann; Nora D Volkow
Dopamine D2R DNA transfer in dopamine D2 receptor-deficient mice: effects on ethanol drinking.
Life sciences 2005;77(2):130-9.
2005: Nora D Volkow; Gene-Jack Wang; Yeming Ma; Joanna S Fowler; Christopher Wong; Yu-Shin Ding; Robert Hitzemann; James M Swanson; Peter W Kalivas
Activation of orbital and medial prefrontal cortex by methylphenidate in cocaine-addicted subjects but not in controls: relevance to addiction.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(15):3932-9.
2005: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Susan Learned-Coughlin; Julia Yang; Jean Logan; David Schlyer; John S Gatley; Christopher Wong; Wei Zhu; Naomi Pappas; Michael Schueller; Millard Jayne; Pauline Carter; Donald Warner; Yu-Shin Ding; Colleen Shea; Youwen Xu
The slow and long-lasting blockade of dopamine transporters in human brain induced by the new antidepressant drug radafaxine predict poor reinforcing effects.
Biological psychiatry 2005;57(6):640-6.
2005: Rita Z Goldstein; Nelly Alia-Klein; Andreana C Leskovjan; Joanna S Fowler; Gene-Jack Wang; Ruben C Gur; Robert Hitzemann; Nora D Volkow
Anger and depression in cocaine addiction: association with the orbitofrontal cortex.
Psychiatry research 2005;138(1):13-22.
2005: S John Gatley; Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Jean Logan; Yu-Shin Ding; Madina R Gerasimov
PET imaging in clinical drug abuse research.
Current pharmaceutical design 2005;11(25):3203-19.
2004: Gene-Jack Wang; Linda Chang; Nora D Volkow; Frank Telang; Jean Logan; Thomas Ernst; Joanna S Fowler
Decreased brain dopaminergic transporters in HIV-associated dementia patients.
Brain : a journal of neurology 2004;127(Pt 11):2452-8.
2004: Yu-Shin Ding; Joanna S Fowler; Jean Logan; Gene-Jack Wang; Frank Telang; Victor Garza; Anat Biegon; Deborah Pareto; William D Rooney; Colleen Shea; David Alexoff; Nora D Volkow; Frank Vocci
6-[18F]Fluoro-A-85380, a new PET tracer for the nicotinic acetylcholine receptor: studies in the human brain and in vivo demonstration of specific binding in white matter.
Synapse (New York, N.Y.) 2004;53(3):184-9.
2004: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Frank Telang; Laurence Maynard; Jean Logan; S John Gatley; Naomi Pappas; Christopher Wong; Paul Vaska; Wei Zhu; James M Swanson
Evidence that methylphenidate enhances the saliency of a mathematical task by increasing dopamine in the human brain.
The American journal of psychiatry 2004;161(7):1173-80.
2004: Panayotis K Thanos; Nicholas B Taintor; Seth N Rivera; Hiroyuki Umegaki; Hiroyuki Ikari; George Roth; Donald Ingram; Robert Hitzemann; Joanna S Fowler; S John Gatley; Gene-Jack Wang; Nora D Volkow
DRD2 gene transfer into the nucleus accumbens core of the alcohol preferring and nonpreferring rats attenuates alcohol drinking.
Alcoholism, clinical and experimental research 2004;28(5):720-8.
2004: Gene-Jack Wang; Nora D Volkow; Frank Telang; Millard Jayne; Jim Ma; Manlong Rao; Wei Zhu; Christopher T Wong; Naomi Pappas; Allan Geliebter; Joanna S Fowler
Exposure to appetitive food stimuli markedly activates the human brain.
NeuroImage 2004;21(4):1790-7.
2004: Joanna S Fowler; Nora D Volkow; Gene-Jack Wang; Yu-Shin Ding
2-deoxy-2-[18F]fluoro-D-glucose and alternative radiotracers for positron emission tomography imaging using the human brain as a model.
Seminars in nuclear medicine 2004;34(2):112-21.
2004: Joanna S Fowler; Jean Logan; Gene-Jack Wang; Nora D Volkow; Frank Telang; Yu-Shin Ding; Colleen Shea; Victor Garza; Youwen Xu; Zizhong Li; David Alexoff; Paul Vaska; Richard Ferrieri; David Schlyer; Wei Zhu; S John Gatley
Comparison of the binding of the irreversible monoamine oxidase tracers, [(11)C]clorgyline and [(11)C]l-deprenyl in brain and peripheral organs in humans.
Nuclear medicine and biology 2004;31(3):313-9.
2004: Gene-Jack Wang; Nora D Volkow; Linda Chang; Eric Miller; Mark Sedler; Robert Hitzemann; Wei Zhu; Jean Logan; Yeming Ma; Joanna S Fowler
Partial recovery of brain metabolism in methamphetamine abusers after protracted abstinence.
The American journal of psychiatry 2004;161(2):242-8.
2004: Nora D Volkow; Joanna S Fowler; Gene-Jack Wang
The addicted human brain viewed in the light of imaging studies: brain circuits and treatment strategies.
Neuropharmacology 2004;47 Suppl 1():3-13.
2004: Gene-Jack Wang; Nora D Volkow; Panayotis K Thanos; Joanna S Fowler
Similarity between obesity and drug addiction as assessed by neurofunctional imaging: a concept review.
Journal of addictive diseases 2004;23(3):39-53.
2004: Rita Z Goldstein; Andreana C Leskovjan; Anne Hoff; Robert Hitzemann; Francine Bashan; Sahib Singh Khalsa; Gene-Jack Wang; Joanna S Fowler; Nora D Volkow
Severity of neuropsychological impairment in cocaine and alcohol addiction: association with metabolism in the prefrontal cortex.
Neuropsychologia 2004;42(11):1447-58.
2004: Wei Zhu; Nora D Volkow; Yeming Ma; Joanna S Fowler; Gene-Jack Wang
Relationship between ethanol-induced changes in brain regional metabolism and its motor, behavioural and cognitive effects.
Alcohol and alcoholism (Oxford, Oxfordshire) 2004;39(1):53-8.
2003: Nora D Volkow; Gene-Jack Wang; Yemin Ma; Joanna S Fowler; Wei Zhu; Laurence Maynard; Frank Telang; Paul Vaska; Yu-Shin Ding; Christopher Wong; James M Swanson
Expectation enhances the regional brain metabolic and the reinforcing effects of stimulants in cocaine abusers.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(36):11461-8.
2003: Joanna S Fowler; Jean Logan; Gene-Jack Wang; Nora D Volkow; Frank Telang; Wei Zhu; Dinko Franceschi; Naomi Pappas; Richard Ferrieri; Colleen Shea; Victor Garza; Youwen Xu; David Schlyer; S John Gatley; Yu-Shin Ding; David Alexoff; Donald Warner; Noelwah Netusil; Pauline Carter; Millard Jayne; Payton King; Paul Vaska
Low monoamine oxidase B in peripheral organs in smokers.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(20):11600-5.
2003: Joanna S Fowler; Jean Logan; Gene-Jack Wang; Dinko Franceschi; Nora D Volkow; Frank Telang; Naomi Pappas; Richard Ferrieri; Colleen Shea; Victor Garza; Youwen Xu; Payton King; David Schlyer; S John Gatley; Yu-Shin Ding; Donald Warner; Noelwah Netusil; Pauline Carter; Millard Jayne; David Alexoff; Wei Zhu; Paul Vaska
Monoamine oxidase A imaging in peripheral organs in healthy human subjects.
Synapse (New York, N.Y.) 2003;49(3):178-87.
2003: Gene-Jack Wang; Nora D Volkow; Joanna S Fowler; Dinko Franceschi; Christopher T Wong; Naomi Pappas; Noelwah Netusil; Wei Zhu; Christoph Felder; Yeming Ma
Alcohol intoxication induces greater reductions in brain metabolism in male than in female subjects.
Alcoholism, clinical and experimental research 2003;27(6):909-17.
2003: Nora D Volkow; Joanna S Fowler; Gene-Jack Wang
The addicted human brain: insights from imaging studies.
The Journal of clinical investigation 2003;111(10):1444-51.
2003: Nora D Volkow; Joanna S Fowler; Gene-Jack Wang
Positron emission tomography and single-photon emission computed tomography in substance abuse research.
Seminars in nuclear medicine 2003;33(2):114-28.
2003: Nora D Volkow; Gene-Jack Wang; Laurence Maynard; Millard Jayne; Joanna S Fowler; Wei Zhu; Jean Logan; S John Gatley; Yu-Shin Ding; Christopher Wong; Naomi Pappas
Brain dopamine is associated with eating behaviors in humans.
The International journal of eating disorders 2003;33(2):136-42.
2003: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Patricia E Molina; Jean Logan; S John Gatley; Andrew N Gifford; Yu-Shin Ding; Christopher Wong; Naomi Pappas; Wei Zhu; James M Swanson
Cardiovascular effects of methylphenidate in humans are associated with increases of dopamine in brain and of epinephrine in plasma.
Psychopharmacology 2003;166(3):264-70.
2003: Joanna S Fowler; Jean Logan; Gene-Jack Wang; Nora D Volkow
Monoamine oxidase and cigarette smoking.
Neurotoxicology 2003;24(1):75-82.
2002: Nora D Volkow; Gene-Jack Wang; Laurence Maynard; Joanna S Fowler; Budd Jayne; Frank Telang; Jean Logan; Yu-Shin Ding; S John Gatley; Robert Hitzemann; Christopher Wong; Naomi Pappas
Effects of alcohol detoxification on dopamine D2 receptors in alcoholics: a preliminary study.
Psychiatry research 2002;116(3):163-72.
2002: Rita Z Goldstein; Nora D Volkow; Linda Chang; Gene-Jack Wang; Joanna S Fowler; Richard A Depue; Ruben C Gur
The orbitofrontal cortex in methamphetamine addiction: involvement in fear.
Neuroreport 2002;13(17):2253-7.
2002: Nora D Volkow; Joanna S Fowler; Gene-Jack Wang; Yu Shin Ding; S John Gatley
Role of dopamine in the therapeutic and reinforcing effects of methylphenidate in humans: results from imaging studies.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2002;12(6):557-66.
2002: Nora D Volkow; Joanna S Fowler; Gene-Jack Wang; Rita Z Goldstein
Role of dopamine, the frontal cortex and memory circuits in drug addiction: insight from imaging studies.
Neurobiology of learning and memory 2002;78(3):610-24.
2002: Jean Logan; Joanna S Fowler; Yu-Shin Ding; Dinko Franceschi; Gene-Jack Wang; Nora D Volkow; Christoph Felder; David Alexoff
Strategy for the formation of parametric images under conditions of low injected radioactivity applied to PET studies with the irreversible monoamine oxidase A tracers [11C]clorgyline and deuterium-substituted [11C]clorgyline.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(11):1367-76.
2002: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Panayotis Peter K Thanos; Jean Logan; S John Gatley; Andrew N Gifford; Yu-Shin Ding; Chris Wong; Naomi Pappas; Pether Thanos
Brain DA D2 receptors predict reinforcing effects of stimulants in humans: replication study.
Synapse (New York, N.Y.) 2002;46(2):79-82.
2002: Gene-Jack Wang; Nora D Volkow; Joanna S Fowler
The role of dopamine in motivation for food in humans: implications for obesity.
Expert opinion on therapeutic targets 2002;6(5):601-9.
2002: Joanna S Fowler; Jean Logan; Gene-Jack Wang; Nora D Volkow; Wei Zhu; Dinko Franceschi; Naomi Pappas; Richard Ferrieri; Colleen Shea; Victor Garza; Youwen Xu; Robert R MacGregor; David Schlyer; S John Gatley; Yu-Shin Ding; David Alexoff
PET imaging of monoamine oxidase B in peripheral organs in humans.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2002;43(10):1331-8.
2002: Nora D Volkow; Joanna S Fowler; Gene-Jack Wang
Role of dopamine in drug reinforcement and addiction in humans: results from imaging studies.
Behavioural pharmacology 2002;13(5-6):355-66.
2002: Gene-Jack Wang; Nora D Volkow; Christoph Felder; Joanna S Fowler; Alejandro V Levy; Naomi Pappas; Christopher T Wong; Wei Zhu; Noelwah Netusil
Enhanced resting activity of the oral somatosensory cortex in obese subjects.
Neuroreport 2002;13(9):1151-5.
2002: Joanna S Fowler; Jean Logan; Nora D Volkow; Gene-Jack Wang; Robert R MacGregor; Yu-Shin Ding
Monoamine oxidase: radiotracer development and human studies.
Methods (San Diego, Calif.) 2002;27(3):263-77.
2002: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Jean Logan; Millard Jayne; Dinko Franceschi; Cristopher Wong; S John Gatley; Andrew N Gifford; Yu-Shin Ding; Naomi Pappas
"Nonhedonic" food motivation in humans involves dopamine in the dorsal striatum and methylphenidate amplifies this effect.
Synapse (New York, N.Y.) 2002;44(3):175-80.
2002: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Jean Logan; Dinko Franceschi; Laurence Maynard; Yu-Shin Ding; S John Gatley; Andrew N Gifford; Wei Zhu; James M Swanson
Relationship between blockade of dopamine transporters by oral methylphenidate and the increases in extracellular dopamine: therapeutic implications.
Synapse (New York, N.Y.) 2002;43(3):181-7.
2002: Nora D Volkow; Wei Zhu; Christoph A Felder; Klaus Mueller; Tomihisa F Welsh; Gene-Jack Wang; Mony J de Leon
Changes in brain functional homogeneity in subjects with Alzheimer's disease.
Psychiatry research 2002;114(1):39-50.
2001: Joanna S Fowler; Jean Logan; Yu-Shin Ding; Dinko Franceschi; Gene-Jack Wang; Nora D Volkow; Naomi Pappas; David Schlyer; S John Gatley; David Alexoff; Christoph Felder; Anat Biegon; Wei Zhu
Non-MAO A binding of clorgyline in white matter in human brain.
Journal of neurochemistry 2001;79(5):1039-46.
2001: Nora D Volkow; Linda Chang; Gene-Jack Wang; Joanna S Fowler; Yu-Shin Ding; Mark Sedler; Jean Logan; Dinko Franceschi; John S Gatley; Robert Hitzemann; Andrew N Gifford; Cristopher Wong; Naomi Pappas
Low level of brain dopamine D2 receptors in methamphetamine abusers: association with metabolism in the orbitofrontal cortex.
The American journal of psychiatry 2001;158(12):2015-21.
2001: Nora D Volkow; Linda Chang; Gene-Jack Wang; Joanna S Fowler; Dinko Franceschi; Mark Sedler; S John Gatley; Eric Miller; Robert Hitzemann; Yu-Shin Ding; Jean Logan
Loss of dopamine transporters in methamphetamine abusers recovers with protracted abstinence.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(23):9414-8.
2001: Joanna S Fowler; Yu-Shin Ding; Jean Logan; Robert R MacGregor; Colleen Shea; Victor Garza; R Gimi; Nora D Volkow; Gene-Jack Wang; David Schlyer; Richard Ferrieri; S John Gatley; David Alexoff; Pauline Carter; Payton King; Naomi Pappas; C D Arnett
Species differences in [11C]clorgyline binding in brain.
Nuclear medicine and biology 2001;28(7):779-85.
2001: Joanna S Fowler; Nora D Volkow; Gene-Jack Wang; S John Gatley; Jean Logan
[(11)]Cocaine: PET studies of cocaine pharmacokinetics, dopamine transporter availability and dopamine transporter occupancy.
Nuclear medicine and biology 2001;28(5):561-72.
2001: Susan De Santi; Mony J de Leon; Henry Rusinek; Antonio Convit; Chaim Y Tarshish; A Roche; Wai Hon Tsui; E Kandil; Madhu Boppana; K Daisley; Gene-Jack Wang; D Schlyer; Joanna S Fowler
Hippocampal formation glucose metabolism and volume losses in MCI and AD.
Neurobiology of aging 2001;22(4):529-39.
2001: Joanna S Fowler; Nora D Volkow; Jean Logan; Dinko Franceschi; Gene-Jack Wang; R MacGregor; Colleen Shea; Victor Garza; Naomi Pappas; Pauline Carter; Noelwah Netusil; P Bridge; D Liederman; Ahmed Elkashef; John Rotrosen; Robert Hitzemann
Evidence that L-deprenyl treatment for one week does not inhibit MAO A or the dopamine transporter in the human brain.
Life sciences 2001;68(24):2759-68.
2001: Jean Logan; Joanna S Fowler; Nora D Volkow; Yu-Shin Ding; Gene-Jack Wang; David Alexoff
A strategy for removing the bias in the graphical analysis method.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2001;21(3):307-20.
2001: Nora D Volkow; Linda Chang; Gene-Jack Wang; Joanna S Fowler; D Franceschi; Mark Sedler; SJ Gatley; Robert Hitzemann; Yu-Shin Ding; Cristopher Wong; Jean Logan
Higher cortical and lower subcortical metabolism in detoxified methamphetamine abusers.
The American journal of psychiatry 2001;158(3):383-9.
2001: Nora D Volkow; Linda Chang; Gene-Jack Wang; Joanna S Fowler; Maria Leonido-Yee; D Franceschi; Mark Sedler; SJ Gatley; Robert Hitzemann; Yu-Shin Ding; Jean Logan; Cristopher Wong; Eric N Miller
Association of dopamine transporter reduction with psychomotor impairment in methamphetamine abusers.
The American journal of psychiatry 2001;158(3):377-82.
2001: Gene-Jack Wang; Nora D Volkow; Jean Logan; Naomi Pappas; Christopher T Wong; Wei Zhu; Noelwah Netusil; Joanna S Fowler
Brain dopamine and obesity.
Lancet 2001;357(9253):354-7.
2000: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; William D Rooney; Christoph Felder; Jing-Huei Lee; Dinko Franceschi; Laurence Maynard; David Schlyer; Jullie W Pan; S John Gatley; C S Springer Jr
Resting brain metabolic activity in a 4 tesla magnetic field.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2000;44(5):701-5.
2000: Joanna S Fowler; Gene-Jack Wang; Nora D Volkow; Dinko Franceschi; Jean Logan; Naomi Pappas; Colleen Shea; Robert R MacGregor; Victor Garza
Maintenance of brain monoamine oxidase B inhibition in smokers after overnight cigarette abstinence.
The American journal of psychiatry 2000;157(11):1864-6.
2000: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Jean Logan; John S Gatley; Naomi Pappas; Christopher T Wong; Christoph Felder
Increased activity of the temporal insula in subjects with bradycardia.
Life sciences 2000;67(18):2213-20.
2000: Nora D Volkow; Gene-Jack Wang; MW Fischman; RW Foltin; Joanna S Fowler; D Franceschi; M Franceschi; Jean Logan; S John Gatley; Cristopher Wong; Yu-Shin Ding; Robert Hitzemann; Naomi Pappas
Effects of route of administration on cocaine induced dopamine transporter blockade in the human brain.
Life sciences 2000;67(12):1507-15.
2000: Gene-Jack Wang; Nora D Volkow; Joanna S Fowler; Dinko Franceschi; Jean Logan; Naomi Pappas; Christopher T Wong; Noelwah Netusil
PET studies of the effects of aerobic exercise on human striatal dopamine release.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2000;41(8):1352-6.
2000: William D Rooney; Jing-Huei Lee; Xin Li; Gene-Jack Wang; Dinko Franceschi; Charles S Springer; Nora D Volkow
4.0 T water proton T1 relaxation times in normal human brain and during acute ethanol intoxication.
Alcoholism, clinical and experimental research 2000;24(6):830-6.
2000: Gene-Jack Wang; Nora D Volkow; Dinko Franceschi; Joanna S Fowler; Panayotis K Thanos; N Scherbaum; Naomi Pappas; Christopher T Wong; Robert Hitzemann; Christoph Felder
Regional brain metabolism during alcohol intoxication.
Alcoholism, clinical and experimental research 2000;24(6):822-9.
2000: Nora D Volkow; S John Gatley; Joanna S Fowler; Gene-Jack Wang; J Swanson
Serotonin and the therapeutic effects of ritalin.
Science (New York, N.Y.) 2000;288(5463):11.
2000: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Dinko Franceschi; Panayotis K Thanos; Cristopher Wong; S John Gatley; Yu-Shin Ding; P Molina; David Schlyer; David Alexoff; Robert Hitzemann; Naomi Pappas
Cocaine abusers show a blunted response to alcohol intoxication in limbic brain regions.
Life sciences 2000;66(12):PL161-7.
2000: Joanna S Fowler; Gene-Jack Wang; Nora D Volkow; Jean Logan; Dinko Franceschi; M Franceschi; R MacGregor; Colleen Shea; Victor Garza; N Liu; Yu-Shin Ding
Evidence that gingko biloba extract does not inhibit MAO A and B in living human brain.
Life sciences 2000;66(9):PL141-6.
2000: Jean Logan; Joanna S Fowler; Nora D Volkow; Gene-Jack Wang; Robert R MacGregor; Colleen Shea
Reproducibility of repeated measures of deuterium substituted [11C]L-deprenyl ([11C]L-deprenyl-D2) binding in the human brain.
Nuclear medicine and biology 2000;27(1):43-9.
2000: Nora D Volkow; Jean Logan; Joanna S Fowler; Gene-Jack Wang; R C Gur; Christopher Wong; C Felder; S John Gatley; Yu-Shin Ding; Robert Hitzemann; Naomi Pappas
Association between age-related decline in brain dopamine activity and impairment in frontal and cingulate metabolism.
The American journal of psychiatry 2000;157(1):75-80.
1999: Joanna S Fowler; Gene-Jack Wang; Nora D Volkow; Dinko Franceschi; Jean Logan; Naomi Pappas; Colleen Shea; Robert R MacGregor; Victor Garza
Smoking a single cigarette does not produce a measurable reduction in brain MAO B in non-smokers.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 1999;1(4):325-9.
1999: Nora D Volkow; Joanna S Fowler; Gene-Jack Wang
Imaging studies on the role of dopamine in cocaine reinforcement and addiction in humans.
Journal of psychopharmacology (Oxford, England) 1999;13(4):337-45.
1999: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Jean Logan; S John Gatley; Cristopher Wong; Robert Hitzemann; Naomi Pappas
Reinforcing effects of psychostimulants in humans are associated with increases in brain dopamine and occupancy of D(2) receptors.
The Journal of pharmacology and experimental therapeutics 1999;291(1):409-15.
1999: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Jean Logan; S John Gatley; A Gifford; Robert Hitzemann; Yu-Shin Ding; Naomi Pappas
Prediction of reinforcing responses to psychostimulants in humans by brain dopamine D2 receptor levels.
The American journal of psychiatry 1999;156(9):1440-3.
1999: Gene-Jack Wang; Nora D Volkow; Joanna S Fowler; Jean Logan; Naomi Pappas; Christopher T Wong; Robert Hitzemann; Noelwah Netusil
Reproducibility of repeated measures of endogenous dopamine competition with [11C]raclopride in the human brain in response to methylphenidate.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1999;40(8):1285-91.
1999: MK Sammi; Christoph Felder; Joanna S Fowler; Jing-Huei Lee; Alejandro V Levy; Xin Li; Jean Logan; I Pályka; William D Rooney; Nora D Volkow; Gene-Jack Wang; Charles S Springer
Intimate combination of low- and high-resolution image data: I. Real-space PET and (1)H(2)O MRI, PETAMRI.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1999;42(2):345-60.
1999: Joanna S Fowler; Nora D Volkow; Yu-Shin Ding; Gene-Jack Wang; Stephen L Dewey; MW Fischman; RW Foltin; Robert Hitzemann
Positron emission tomography studies of dopamine-enhancing drugs.
Journal of clinical pharmacology 1999;Suppl():13S-16S.
1999: Joanna S Fowler; Nora D Volkow; Gene-Jack Wang; Yu-Shin Ding; Stephen L Dewey
PET and drug research and development.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1999;40(7):1154-63.
1999: Gene-Jack Wang; Nora D Volkow; Alejandro V Levy; Christoph Felder; Joanna S Fowler; Naomi Pappas; Robert Hitzemann; Christopher T Wong
Measuring reproducibility of regional brain metabolic responses to lorazepam using statistical parametric maps.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1999;40(5):715-20.
1999: Frank Telang; Nora D Volkow; A Levy; Jean Logan; Joanna S Fowler; C Felder; Cristopher Wong; Gene-Jack Wang
Distribution of tracer levels of cocaine in the human brain as assessed with averaged [11C]cocaine images.
Synapse (New York, N.Y.) 1999;31(4):290-6.
1999: Nora D Volkow; Joanna S Fowler; Yu-Shin Ding; Gene-Jack Wang; S John Gatley
Imaging the neurochemistry of nicotine actions: studies with positron emission tomography.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 1999;1 Suppl 2():S127-32; discussion S139-40.
1999: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; MW Fischman; RW Foltin; Naji N Abumrad; S John Gatley; Jean Logan; Cristopher Wong; Andrew N Gifford; Yu-Shin Ding; Robert Hitzemann; Naomi Pappas
Methylphenidate and cocaine have a similar in vivo potency to block dopamine transporters in the human brain.
Life sciences 1999;65(1):PL7-12.
1999: Gene-Jack Wang; Nora D Volkow; Joanna S Fowler; P Cervany; Robert Hitzemann; Naomi Pappas; Christopher T Wong; Christoph Felder
Regional brain metabolic activation during craving elicited by recall of previous drug experiences.
Life sciences 1999;64(9):775-84.
1999: Nora D Volkow; Joanna S Fowler; S John Gatley; Stephen L Dewey; Gene-Jack Wang; Jean Logan; Yu-Shin Ding; Dinko Franceschi; Andrew N Gifford; A Morgan; Naomi Pappas; Payton King
Comparable changes in synaptic dopamine induced by methylphenidate and by cocaine in the baboon brain.
Synapse (New York, N.Y.) 1999;31(1):59-66.
1999: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Robert Hitzemann; B Angrist; S John Gatley; Jean Logan; Yu-Shin Ding; Naomi Pappas
Association of methylphenidate-induced craving with changes in right striato-orbitofrontal metabolism in cocaine abusers: implications in addiction.
The American journal of psychiatry 1999;156(1):19-26.
1999: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; S John Gatley; Jean Logan; Yu-Shin Ding; Stephen L Dewey; Robert Hitzemann; Andrew N Gifford; Naomi Pappas
Blockade of striatal dopamine transporters by intravenous methylphenidate is not sufficient to induce self-reports of "high".
The Journal of pharmacology and experimental therapeutics 1999;288(1):14-20.
1998: Gene-Jack Wang; Nora D Volkow; Joanna S Fowler; Naomi Pappas; Christopher T Wong; K Pascani; Christoph Felder; Robert Hitzemann
Regional cerebral metabolism in female alcoholics of moderate severity does not differ from that of controls.
Alcoholism, clinical and experimental research 1998;22(8):1850-4.
1998: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; S John Gatley; Jean Logan; Yu-Shin Ding; Robert Hitzemann; Naomi Pappas
Dopamine transporter occupancies in the human brain induced by therapeutic doses of oral methylphenidate.
The American journal of psychiatry 1998;155(10):1325-31.
1998: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Robert Hitzemann; John S Gatley; Yu-Shin Ding; Cristopher Wong; Naomi Pappas
Differences in regional brain metabolic responses between single and repeated doses of methylphenidate.
Psychiatry research 1998;83(1):29-36.
1998: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Yu-Shin Ding; R C Gur; John S Gatley; Jean Logan; Paul Moberg; Robert Hitzemann; Gwenn S Smith; Naomi Pappas
Parallel loss of presynaptic and postsynaptic dopamine markers in normal aging.
Annals of neurology 1998;44(1):143-7.
1998: Gene-Jack Wang; Nora D Volkow; Joanna S Fowler; Robert Hitzemann; Naomi Pappas; Noelwah Netusil
Evaluation of gender difference in regional brain metabolic responses to lorazepam.
Psychiatry research 1998;82(1):37-46.
1998: Nora D Volkow; R C Gur; Gene-Jack Wang; Joanna S Fowler; Paul Moberg; Yu-Shin Ding; Robert Hitzemann; Gwenn S Smith; Jean Logan
Association between decline in brain dopamine activity with age and cognitive and motor impairment in healthy individuals.
The American journal of psychiatry 1998;155(3):344-9.
1998: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Robert Hitzemann; S John Gatley; S S Dewey; Naomi Pappas
Enhanced sensitivity to benzodiazepines in active cocaine-abusing subjects: a PET study.
The American journal of psychiatry 1998;155(2):200-6.
1998: Joanna S Fowler; Nora D Volkow; Jean Logan; S John Gatley; Naomi Pappas; Payton King; Yu-Shin Ding; Gene-Jack Wang
Measuring dopamine transporter occupancy by cocaine in vivo: radiotracer considerations.
Synapse (New York, N.Y.) 1998;28(2):111-6.
1998: Joanna S Fowler; Nora D Volkow; Gene-Jack Wang; Naomi Pappas; Jean Logan; R MacGregor; David Alexoff; AP Wolf; Donald Warner; R Cilento; I Zezulkova
Neuropharmacological actions of cigarette smoke: brain monoamine oxidase B (MAO B) inhibition.
Journal of addictive diseases 1998;17(1):23-34.
1998: Ralf Schlösser; Jonathan D Brodie; Stephen L Dewey; David Alexoff; Gene-Jack Wang; Joanna S Fowler; Nora D Volkow; Jean Logan; AP Wolf
Long-term stability of neurotransmitter activity investigated with 11C-raclopride PET.
Synapse (New York, N.Y.) 1998;28(1):66-70.
1998: Joanna S Fowler; Nora D Volkow; Gene-Jack Wang; Naomi Pappas; Colleen Shea; Robert R MacGregor; Jean Logan
Visualization of monoamine oxidase in human brain.
Advances in pharmacology (San Diego, Calif.) 1998;42():304-7.
1998: Nora D Volkow; Joanna S Fowler; Yu-Shin Ding; Gene-Jack Wang; SJ Gatley
Positron emission tomography radioligands for dopamine transporters and studies in human and nonhuman primates.
Advances in pharmacology (San Diego, Calif.) 1998;42():211-4.
1997: Jean Logan; Nora D Volkow; Joanna S Fowler; Gene-Jack Wang; MW Fischman; RW Foltin; Naji N Abumrad; SA Vitkun; S John Gatley; Naomi Pappas; Robert Hitzemann; C E Shea
Concentration and occupancy of dopamine transporters in cocaine abusers with [11C]cocaine and PET.
Synapse (New York, N.Y.) 1997;27(4):347-56.
1997: Nora D Volkow; Gene-Jack Wang; J E Overall; Robert Hitzemann; Joanna S Fowler; Naomi Pappas; Ede Frecska; Kathy Piscani
Regional brain metabolic response to lorazepam in alcoholics during early and late alcohol detoxification.
Alcoholism, clinical and experimental research 1997;21(7):1278-84.
1997: Joanna S Fowler; Nora D Volkow; Gene-Jack Wang; Jean Logan; Naomi Pappas; Colleen Shea; R MacGregor
Age-related increases in brain monoamine oxidase B in living healthy human subjects.
Neurobiology of aging 1997;18(4):431-5.
1997: Yu-Shin Ding; Joanna S Fowler; Nora D Volkow; Stephen L Dewey; Gene-Jack Wang; Jean Logan; S John Gatley; Naomi Pappas
Chiral drugs: comparison of the pharmacokinetics of [11C]d-threo and L-threo-methylphenidate in the human and baboon brain.
Psychopharmacology 1997;131(1):71-8.
1997: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Jean Logan; S John Gatley; Robert Hitzemann; A D Chen; Stephen L Dewey; Naomi Pappas
Decreased striatal dopaminergic responsiveness in detoxified cocaine-dependent subjects.
Nature 1997;386(6627):830-3.
1997: Nora D Volkow; Gene-Jack Wang; MW Fischman; RW Foltin; Joanna S Fowler; Naji N Abumrad; SA Vitkun; Jean Logan; S John Gatley; Naomi Pappas; Robert Hitzemann; C E Shea
Relationship between subjective effects of cocaine and dopamine transporter occupancy.
Nature 1997;386(6627):827-30.
1997: S John Gatley; Nora D Volkow; Andrew N Gifford; Yu-Shin Ding; Jean Logan; Gene-Jack Wang
Model for estimating dopamine transporter occupancy and subsequent increases in synaptic dopamine using positron emission tomography and carbon-11-labeled cocaine.
Biochemical pharmacology 1997;53(1):43-52.
1997: Gene-Jack Wang; Nora D Volkow; Joanna S Fowler; MW Fischman; RW Foltin; Naji N Abumrad; Jean Logan; Naomi Pappas
Cocaine abusers do not show loss of dopamine transporters with age.
Life sciences 1997;61(11):1059-65.
1997: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Robert Hitzemann; Naomi Pappas; K Pascani; Cristopher Wong
Gender differences in cerebellar metabolism: test-retest reproducibility.
The American journal of psychiatry 1997;154(1):119-21.
1997: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Jean Logan; B Angrist; Robert Hitzemann; J Lieberman; Naomi Pappas
Effects of methylphenidate on regional brain glucose metabolism in humans: relationship to dopamine D2 receptors.
The American journal of psychiatry 1997;154(1):50-5.
1996: Nora D Volkow; S John Gatley; Joanna S Fowler; Jean Logan; MW Fischman; Andrew N Gifford; Naomi Pappas; Payton King; SA Vitkun; Yu-Shin Ding; Gene-Jack Wang
Cocaine doses equivalent to those abused by humans occupy most of the dopamine transporters.
Synapse (New York, N.Y.) 1996;24(4):399-402.
1996: Eisei Noiri; Michael S Goligorsky; Gene-Jack Wang; J Wang; C J Cabahug; S Sharma; B A Rhodes; P Som
Biodistribution and clearance of 99mTc-labeled Arg-Gly-Asp (RGD) peptide in rats with ischemic acute renal failure.
Journal of the American Society of Nephrology : JASN 1996;7(12):2682-8.
1996: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Jean Logan; Robert Hitzemann; Yu-Shin Ding; Naomi Pappas; Colleen Shea; K Piscani
Decreases in dopamine receptors but not in dopamine transporters in alcoholics.
Alcoholism, clinical and experimental research 1996;20(9):1594-8.
1996: Joanna S Fowler; Nora D Volkow; Gene-Jack Wang; Naomi Pappas; Jean Logan; Colleen Shea; David Alexoff; Robert R MacGregor; David Schlyer; I Zezulkova; AP Wolf
Brain monoamine oxidase A inhibition in cigarette smokers.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(24):14065-9.
1996: Gene-Jack Wang; Nora D Volkow; J Overall; Robert Hitzemann; Naomi Pappas; K Pascani; Joanna S Fowler
Reproducibility of regional brain metabolic responses to lorazepam.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996;37(10):1609-13.
1996: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; S John Gatley; Yu-Shin Ding; Jean Logan; Stephen L Dewey; Robert Hitzemann; J Lieberman
Relationship between psychostimulant-induced "high" and dopamine transporter occupancy.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(19):10388-92.
1996: Gene-Jack Wang; Nora D Volkow; Y H Lau; Joanna S Fowler; A G Meek; T L Park; C Wong; C T Roque; A J Adler; AP Wolf
Glucose metabolic changes in nontumoral brain tissue of patients with brain tumor following radiotherapy: a preliminary study.
Journal of computer assisted tomography 1996;20(5):709-14.
1996: Jean Logan; Joanna S Fowler; Nora D Volkow; Gene-Jack Wang; Yu-Shin Ding; David Alexoff
Distribution volume ratios without blood sampling from graphical analysis of PET data.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1996;16(5):834-40.
1996: Nora D Volkow; Joanna S Fowler; S John Gatley; Jean Logan; Gene-Jack Wang; Yu-Shin Ding; Stephen L Dewey
PET evaluation of the dopamine system of the human brain.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996;37(7):1242-56.
1996: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Jean Logan; S John Gatley; Robert R MacGregor; David Schlyer; Robert Hitzemann; AP Wolf
Measuring age-related changes in dopamine D2 receptors with 11C-raclopride and 18F-N-methylspiroperidol.
Psychiatry research 1996;67(1):11-6.
1996: Gene-Jack Wang; Nora D Volkow; A V Levy; Joanna S Fowler; Jean Logan; David Alexoff; Robert Hitzemann; D J Schyler
MR-PET image coregistration for quantitation of striatal dopamine D2 receptors.
Journal of computer assisted tomography 1996;20(3):423-8.
1996: Nora D Volkow; Yu-Shin Ding; Joanna S Fowler; Gene-Jack Wang; Jean Logan; S John Gatley; Robert Hitzemann; Gwenn S Smith; S D Fields; R Gur
Dopamine transporters decrease with age.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996;37(4):554-9.
1996: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Jean Logan; R Hitzemannn; S J Gatley; R R MacGregor; AP Wolf
Cocaine uptake is decreased in the brain of detoxified cocaine abusers.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1996;14(3):159-68.
1996: Joanna S Fowler; Nora D Volkow; Gene-Jack Wang; Naomi Pappas; Jean Logan; R MacGregor; David Alexoff; Colleen Shea; David Schlyer; AP Wolf; D Warner; I Zezulkova; R Cilento
Inhibition of monoamine oxidase B in the brains of smokers.
Nature 1996;379(6567):733-6.
1996: Nora D Volkow; Yu-Shin Ding; Joanna S Fowler; Gene-Jack Wang
Cocaine addiction: hypothesis derived from imaging studies with PET.
Journal of addictive diseases 1996;15(4):55-71.
1996: Nora D Volkow; Gene-Jack Wang; S John Gatley; Joanna S Fowler; Yu-Shin Ding; Jean Logan; Robert Hitzemann; B Angrist; J Lieberman
Temporal relationships between the pharmacokinetics of methylphenidate in the human brain and its behavioral and cardiovascular effects.
Psychopharmacology 1996;123(1):26-33.
1996: Gene-Jack Wang; Nora D Volkow; Joanna S Fowler; Jean Logan; R Gur; Noelwah Netusil; Robert Hitzemann; Naomi Pappas
Age associated decrements in dopamine D2 receptors in thalamus and in temporal insula of human subjects.
Life sciences 1996;59(1):PL31-5.
1995: Nora D Volkow; L R Tancredi; C Grant; H Gillespie; A Valentine; N Mullani; Gene-Jack Wang; L Hollister
Brain glucose metabolism in violent psychiatric patients: a preliminary study.
Psychiatry research 1995;61(4):243-53.
1995: Nora D Volkow; Joanna S Fowler; Jean Logan; S John Gatley; Stephen L Dewey; Robert R MacGregor; David Schlyer; Naomi Pappas; Payton King; Gene-Jack Wang
Carbon-11-cocaine binding compared at subpharmacological and pharmacological doses: a PET study.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1995;36(7):1289-97.
1995: Joanna S Fowler; Gene-Jack Wang; Jean Logan; S Xie; Nora D Volkow; Robert R MacGregor; David Schlyer; Naomi Pappas; David Alexoff; C Patlak
Selective reduction of radiotracer trapping by deuterium substitution: comparison of carbon-11-L-deprenyl and carbon-11-deprenyl-D2 for MAO B mapping.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1995;36(7):1255-62.
1995: Nora D Volkow; Yu-Shin Ding; Joanna S Fowler; Gene-Jack Wang; Jean Logan; John S Gatley; S Dewey; C Ashby; J Liebermann; Robert Hitzemann
Is methylphenidate like cocaine? Studies on their pharmacokinetics and distribution in the human brain.
Archives of general psychiatry 1995;52(6):456-63.
1995: Nora D Volkow; Gene-Jack Wang; Robert Hitzemann; Joanna S Fowler; Naomi Pappas; P Lowrimore; G Burr; K Pascani; J Overall; AP Wolf
Depression of thalamic metabolism by lorazepam is associated with sleepiness.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1995;12(2):123-32.
1995: Nora D Volkow; Gene-Jack Wang; H Begleiter; Robert Hitzemann; Naomi Pappas; G Burr; K Pascani; C Wong; Joanna S Fowler; AP Wolf
Regional brain metabolic response to lorazepam in subjects at risk for alcoholism.
Alcoholism, clinical and experimental research 1995;19(2):510-6.
1995: Gene-Jack Wang; Nora D Volkow; Jean Logan; Joanna S Fowler; David Schlyer; Robert R MacGregor; Robert Hitzemann; Albert Gjedde; AP Wolf
Serotonin 5-HT2 receptor availability in chronic cocaine abusers.
Life sciences 1995;56(16):PL299-303.
1995: K A Yousef; Nora D Volkow; David Schlyer; Joanna S Fowler; AP Wolf; Gene-Jack Wang; M R Smith; Jonathan D Brodie; D Warner
Haloperidol blocks the uptake of [18F]N-methylspiroperidol by extrastriatal dopamine receptors in schizophrenic patients.
Synapse (New York, N.Y.) 1995;19(1):14-7.
1995: Gene-Jack Wang; Nora D Volkow; Joanna S Fowler; Yu-Shin Ding; Jean Logan; S John Gatley; Robert R MacGregor; AP Wolf
Comparison of two pet radioligands for imaging extrastriatal dopamine transporters in human brain.
Life sciences 1995;57(14):PL187-91.
1995: Gene-Jack Wang; Nora D Volkow; Jean Logan; Joanna S Fowler; David Schlyer; Robert R MacGregor; Robert Hitzemann; R C Gur; AP Wolf
Evaluation of age-related changes in serotonin 5-HT2 and dopamine D2 receptor availability in healthy human subjects.
Life sciences 1995;56(14):PL249-53.
1994: Jean Logan; Nora D Volkow; Joanna S Fowler; Gene-Jack Wang; Stephen L Dewey; R MacGregor; David Schlyer; S John Gatley; Naomi Pappas; Payton King
Effects of blood flow on [11C]raclopride binding in the brain: model simulations and kinetic analysis of PET data.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1994;14(6):995-1010.
1994: Joanna S Fowler; Nora D Volkow; Jean Logan; Gene-Jack Wang; Robert R MacGregor; D Schyler; AP Wolf; Naomi Pappas; David Alexoff; Colleen Shea
Slow recovery of human brain MAO B after L-deprenyl (Selegeline) withdrawal.
Synapse (New York, N.Y.) 1994;18(2):86-93.
1994: Gene-Jack Wang; Nora D Volkow; AP Wolf; Jonathan D Brodie; Robert Hitzemann
Intersubject variability of brain glucose metabolic measurements in young normal males.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1994;35(9):1457-66.
1994: Nora D Volkow; Joanna S Fowler; Gene-Jack Wang; Jean Logan; David Schlyer; R MacGregor; Robert Hitzemann; AP Wolf
Decreased dopamine transporters with age in health human subjects.
Annals of neurology 1994;36(2):237-9.
1994: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Jean Logan; David Schlyer; Robert Hitzemann; J Lieberman; B Angrist; Naomi Pappas; R MacGregor
Imaging endogenous dopamine competition with [11C]raclopride in the human brain.
Synapse (New York, N.Y.) 1994;16(4):255-62.
1994: Gene-Jack Wang; P Som; Z H Oster; Nora D Volkow; F F Knapp; D F Sacker
Quantitative autoradiographic measurement of cocaine-induced regional myocardial metabolic changes in hypertensive rats.
Nuclear medicine and biology 1994;21(2):245-50.
1994: Nora D Volkow; Gene-Jack Wang; Robert Hitzemann; Joanna S Fowler; J E Overall; G Burr; AP Wolf
Recovery of brain glucose metabolism in detoxified alcoholics.
The American journal of psychiatry 1994;151(2):178-83.
1994: Gene-Jack Wang; Nora D Volkow; AP Wolf; S Madajewicz; Joanna S Fowler; David Schlyer; Robert R MacGregor
Positron emission tomography study of human prostatic adenocarcinoma using carbon-11 putrescine.
Nuclear medicine and biology 1994;21(1):77-82.
1994: Gene-Jack Wang; Nora D Volkow; Joanna S Fowler; R Ferrieri; David Schlyer; David Alexoff; Naomi Pappas; J Lieberman; Payton King; D Warner
Methylphenidate decreases regional cerebral blood flow in normal human subjects.
Life sciences 1994;54(9):PL143-6.
1994: P Som; Z H Oster; Gene-Jack Wang; Nora D Volkow; D F Sacker
Spatial and temporal distribution of cocaine and effects of pharmacological interventions: wholebody autoradiographic microimaging studies.
Life sciences 1994;55(17):1375-82.
1993: Gene-Jack Wang; Nora D Volkow; Joanna S Fowler; AP Wolf; Robert R MacGregor; C E Shea; David Schlyer; Robert Hitzemann
Comparison of two PET radioligands for imaging extrastriatal dopamine receptors in the human brain.
Synapse (New York, N.Y.) 1993;15(3):246-9.
1993: Joanna S Fowler; Nora D Volkow; Jean Logan; David Schlyer; Robert R MacGregor; Gene-Jack Wang; AP Wolf; Naomi Pappas; David Alexoff; Colleen Shea
Monoamine oxidase B (MAO B) inhibitor therapy in Parkinson's disease: the degree and reversibility of human brain MAO B inhibition by Ro 19 6327.
Neurology 1993;43(10):1984-92.
1993: Nora D Volkow; Joanna S Fowler; Gene-Jack Wang; Robert Hitzemann; Jean Logan; David Schlyer; Stephen L Dewey; AP Wolf
Decreased dopamine D2 receptor availability is associated with reduced frontal metabolism in cocaine abusers.
Synapse (New York, N.Y.) 1993;14(2):169-77.
1993: Nora D Volkow; Joanna S Fowler; Gene-Jack Wang; Stephen L Dewey; David Schlyer; R MacGregor; Jean Logan; David Alexoff; Colleen Shea; Robert Hitzemann
Reproducibility of repeated measures of carbon-11-raclopride binding in the human brain.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1993;34(4):609-13.
1993: Nora D Volkow; Gene-Jack Wang; Robert Hitzemann; Joanna S Fowler; AP Wolf; Naomi Pappas; A Biegon; Stephen L Dewey
Decreased cerebral response to inhibitory neurotransmission in alcoholics.
The American journal of psychiatry 1993;150(3):417-22.
1993: Z H Oster; P Som; BA Rhodes; Christopher T Wong; C Cabahug; D F Sacker; Gene-Jack Wang; G E Meinken
Abscess scintigraphy with 99mTc-human immunoglobulin (IgG) using a one-step labeling method.
Nuclear medicine and biology 1993;20(2):225-30.
1993: Gene-Jack Wang; Nora D Volkow; C T Roque; V L Cestaro; Robert Hitzemann; E L Cantos; A V Levy; Atam P Dhawan
Functional importance of ventricular enlargement and cortical atrophy in healthy subjects and alcoholics as assessed with PET, MR imaging, and neuropsychologic testing.
Radiology 1993;186(1):59-65.
1992: Joanna S Fowler; Nora D Volkow; Jean Logan; Robert R MacGregor; Gene-Jack Wang; AP Wolf
Alcohol intoxication does not change [11C]cocaine pharmacokinetics in human brain and heart.
Synapse (New York, N.Y.) 1992;12(3):228-35.
1992: Nora D Volkow; Robert Hitzemann; Gene-Jack Wang; Joanna S Fowler; G Burr; K Pascani; Stephen L Dewey; AP Wolf
Decreased brain metabolism in neurologically intact healthy alcoholics.
The American journal of psychiatry 1992;149(8):1016-22.
1992: Nora D Volkow; Robert Hitzemann; Gene-Jack Wang; Joanna S Fowler; AP Wolf; Stephen L Dewey; L Handlesman
Long-term frontal brain metabolic changes in cocaine abusers.
Synapse (New York, N.Y.) 1992;11(3):184-90.
1992: Gene-Jack Wang; Nora D Volkow; Robert Hitzemann; Z H Oster; C Roque; V Cestaro
Brain imaging of an alcoholic with MRI, SPECT, and PET.
American journal of physiologic imaging 1992;7(3-4):194-8.
1992: Nora D Volkow; Joanna S Fowler; AP Wolf; Gene-Jack Wang; Jean Logan; R MacGregor; Stephen L Dewey; David Schlyer; Robert Hitzemann
Distribution and kinetics of carbon-11-cocaine in the human body measured with PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1992;33(4):521-5.
1991: Z H Oster; P Som; Gene-Jack Wang; D A Weber
Imaging of cocaine-induced global and regional myocardial ischemia.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1991;32(8):1569-72.