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Shinichi Aizawa

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Takaya Abe; Shinichi Aizawa; Toshitaka Horiuchi; Ken-ichi Inoue; Hiroshi Kiyonari; Atsushi Miyawaki; Kazuki Nakao; Asako Sakaue-Sawano; Go Shioi; Toshihiko Fujimori
Visualization of cell cycle in mouse embryos with Fucci2 reporter directed by Rosa26 promoter.
Tomomi Ohmura; Go Shioi; Mariko Hirano; Shinichi Aizawa
Neural tube defects by NUAK1 and NUAK2 double mutation.
Fumitaka Inoue; Daisuke Kurokawa; Maiko Takahashi; Shinichi Aizawa
Gbx2 directly restricts Otx2 expression to forebrain and midbrain, competing with class III POU factors.

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2013: Takaya Abe; Shinichi Aizawa; Toshitaka Horiuchi; Ken-ichi Inoue; Hiroshi Kiyonari; Atsushi Miyawaki; Kazuki Nakao; Asako Sakaue-Sawano; Go Shioi; Toshihiko Fujimori
Visualization of cell cycle in mouse embryos with Fucci2 reporter directed by Rosa26 promoter.
Development (Cambridge, England) 2013;140(1):237-46.
2012: Tomomi Ohmura; Go Shioi; Mariko Hirano; Shinichi Aizawa
Neural tube defects by NUAK1 and NUAK2 double mutation.
Developmental dynamics : an official publication of the American Association of Anatomists 2012;241(8):1350-64.
2012: Fumitaka Inoue; Daisuke Kurokawa; Maiko Takahashi; Shinichi Aizawa
Gbx2 directly restricts Otx2 expression to forebrain and midbrain, competing with class III POU factors.
Molecular and cellular biology 2012;32(13):2618-27.
2012: Hirotaka Tao; Shinichi Aizawa; Jeffrey D Axelrod; Alexander G Bassuk; Ken-ichi Inoue; Hiroshi Kiyonari; Hiroshi Sasaki; Naoto Ueno
Nuclear localization of Prickle2 is required to establish cell polarity during early mouse embryogenesis.
Developmental biology 2012;364(2):138-48.
2012: Daisuke Kurokawa; Tomomi Ohmura; Koji Akasaka; Shinichi Aizawa
A lineage specific enhancer drives Otx2 expression in teleost organizer tissues.
Mechanisms of development 2012;128(11-12):653-61.
2011: Go Shioi; Takaya Abe; Haruhiko Akiyama; Richard R Behringer; Toshihiko Fujimori; Cheng-Chiu Huang; Chuan-Wei Jang; Hiroshi Kiyonari; Kazuki Nakao; Shinichi Aizawa
A mouse reporter line to conditionally mark nuclei and cell membranes for in vivo live-imaging.
Genesis (New York, N.Y. : 2000) 2011;49(7):570-8.
2011: Takaya Abe; Shinichi Aizawa; Ken-Ichi Inoue; Hiroshi Kiyonari; Kazuki Nakao; Go Shioi; Toshihiko Fujimori
Establishment of conditional reporter mouse lines at ROSA26 locus for live cell imaging.
Genesis (New York, N.Y. : 2000) 2011;49(7):579-90.
2011: Masao Doi; Atsushi Ishida; Akiko Miyake; Miho Sato; Rie Komatsu; Fumiyoshi Yamazaki; Ikuo Kimura; Soken Tsuchiya; Hiroshi Kori; Kazuyuki Seo; Yoshiaki Yamaguchi; Masahiro Matsuo; Jean-Michel Fustin; Rina Tanaka; Yasuko Santo; Hiroyuki Yamada; Yukari Takahashi; Michihiro Araki; Kazuki Nakao; Shinichi Aizawa; Masaki Kobayashi; Karl Obrietan; Gozoh Tsujimoto; Hitoshi Okamura
Circadian regulation of intracellular G-protein signalling mediates intercellular synchrony and rhythmicity in the suprachiasmatic nucleus.
Nature communications 2011;2():327.
2010: Yusuke Sakurai; Daisuke Kurokawa; Hiroshi Kiyonari; Eriko Kajikawa; Yoko Suda; Shinichi Aizawa
Otx2 and Otx1 protect diencephalon and mesencephalon from caudalization into metencephalon during early brain regionalization.
Developmental biology 2010;347(2):392-403.
2010: Yoko Suda; Kenji Kokura; Jun Kimura; Eriko Kajikawa; Fumitaka Inoue; Shinichi Aizawa
The same enhancer regulates the earliest Emx2 expression in caudal forebrain primordium, subsequent expression in dorsal telencephalon and later expression in the cortical ventricular zone.
Development (Cambridge, England) 2010;137(17):2939-49.
2010: Daisuke Kurokawa; Tomomi Ohmura; Hajime Ogino; Masaki Takeuchi; Ai Inoue; Fumitaka Inoue; Yoko Suda; Shinichi Aizawa
Evolutionary origin of the Otx2 enhancer for its expression in visceral endoderm.
Developmental biology 2010;342(1):110-20.
2010: Hiroshi Kiyonari; Mari Kaneko; Shin-ichi Abe; Shinichi Aizawa
Three inhibitors of FGF receptor, ERK, and GSK3 establishes germline-competent embryonic stem cells of C57BL/6N mouse strain with high efficiency and stability.
Genesis (New York, N.Y. : 2000) 2010;48(5):317-27.
2009: Masaki Takeuchi; Maiko Takahashi; Masataka Okabe; Shinichi Aizawa
Germ layer patterning in bichir and lamprey; an insight into its evolution in vertebrates.
Developmental biology 2009;332(1):90-102.
2009: Masaki Takeuchi; Masataka Okabe; Shinichi Aizawa
Whole-mount in situ hybridization of bichir (Polypterus) embryos.
Cold Spring Harbor protocols 2009;2009(5):pdb.prot5158.
2009: Masaki Takeuchi; Masataka Okabe; Shinichi Aizawa
Microinjection of bichir (Polypterus) embryos.
Cold Spring Harbor protocols 2009;2009(5):pdb.prot5157.
2009: Masaki Takeuchi; Masataka Okabe; Shinichi Aizawa
The genus Polypterus (bichirs): a fish group diverged at the stem of ray-finned fishes (Actinopterygii).
Cold Spring Harbor protocols 2009;2009(5):pdb.emo117.
2009: Yoko Suda; Daisuke Kurokawa; Masaki Takeuchi; Eriko Kajikawa; Shigeru Kuratani; Chris Amemiya; Shinichi Aizawa
Evolution of Otx paralogue usages in early patterning of the vertebrate head.
Developmental biology 2009;325(1):282-95.
2008: Mikihito Shibata; Daisuke Kurokawa; Hiromi Nakao; Tomomi Ohmura; Shinichi Aizawa
MicroRNA-9 modulates Cajal-Retzius cell differentiation by suppressing Foxg1 expression in mouse medial pallium.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(41):10415-21.
2008: Mariko Hirano; Shigeru Hashimoto; Shigenobu Yonemura; Hisataka Sabe; Shinichi Aizawa
EPB41L5 functions to post-transcriptionally regulate cadherin and integrin during epithelial-mesenchymal transition.
The Journal of cell biology 2008;182(6):1217-30.
2008: Yasunari Yamanaka; Toshio Heike; Tomohiro Kumada; Minoru Shibata; Yuki Takaoka; Ayumi Kitano; Kazuhiro Shiraishi; Takeo Kato; Masako Nagato; Katsuya Okawa; Kenryo Furushima; Kazuki Nakao; Yukio Nakamura; Makoto Mark Taketo; Shinichi Aizawa; Tatsutoshi Nakahata
Loss of Borealin/DasraB leads to defective cell proliferation, p53 accumulation and early embryonic lethality.
Mechanisms of development 2008;125(5-6):441-50.
2007: Kenryo Furushima; Akihito Yamamoto; Takashi Nagano; Mikihito Shibata; Hitoshi Miyachi; Takaya Abe; Naoko Ohshima; Hiroshi Kiyonari; Shinichi Aizawa
Mouse homologues of Shisa antagonistic to Wnt and Fgf signalings.
Developmental biology 2007;306(2):480-92.
2007: Chiharu Kimura-Yoshida; E Tian; Hiroshi Nakano; Saori Amazaki; Kayo Shimokawa; Janet Rossant; Shinichi Aizawa; Isao Matsuo
Crucial roles of Foxa2 in mouse anterior-posterior axis polarization via regulation of anterior visceral endoderm-specific genes.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(14):5919-24.
2007: Nobuyoshi Takasaki; Daisuke Kurokawa; Rika Nakayama; Jun-Ichi Nakayama; Shinichi Aizawa
Acetylated YY1 regulates Otx2 expression in anterior neuroectoderm at two cis-sites 90 kb apart.
The EMBO journal 2007;26(6):1649-59.
2006: Daisuke Kurokawa; Yusuke Sakurai; Ai Inoue; Rika Nakayama; Nobuyoshi Takasaki; Yoko Suda; Tsutomu Miyake; Chris T Amemiya; Shinichi Aizawa
Evolutionary constraint on Otx2 neuroectoderm enhancers-deep conservation from skate to mouse and unique divergence in teleost.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(51):19350-5.
2006: Takashi Nagano; Shoko Takehara; Maiko Takahashi; Shinichi Aizawa; Akihito Yamamoto
Shisa2 promotes the maturation of somitic precursors and transition to the segmental fate in Xenopus embryos.
Development (Cambridge, England) 2006;133(23):4643-54.
2006: Mariko Hirano; Hiroshi Kiyonari; Ai Inoue; Kenryo Furushima; Takuya Murata; Yoko Suda; Shinichi Aizawa
A new serine/threonine protein kinase, Omphk1, essential to ventral body wall formation.
Developmental dynamics : an official publication of the American Association of Anatomists 2006;235(8):2229-37.
2005: Chiharu Kimura-Yoshida; Hiroshi Nakano; Daiji Okamura; Kazuki Nakao; Shigenobu Yonemura; Jose Belo; Shinichi Aizawa; Yasuhisa Matsui; Isao Matsuo
Canonical Wnt signaling and its antagonist regulate anterior-posterior axis polarization by guiding cell migration in mouse visceral endoderm.
Developmental cell 2005;9(5):639-50.
2005: Kenryo Furushima; Takuya Murata; Hiroshi Kiyonari; Shinichi Aizawa
Characterization of Opr deficiency in mouse brain: subtle defects in dorsomedial telencephalon and medioventral forebrain.
Developmental dynamics : an official publication of the American Association of Anatomists 2005;232(4):1056-61.
2005: Mariko Hirano; Takuya Murata; Kenryo Furushima; Hiroshi Kiyonari; Miwa Nakamura; Yoko Suda; Shinichi Aizawa
cfm is a novel gene uniquely expressed in developing forebrain and midbrain, but its null mutant exhibits no obvious phenotype.
Gene expression patterns : GEP 2005;5(3):439-44.
2005: Akihito Yamamoto; Takashi Nagano; Shoko Takehara; Masahiko Hibi; Shinichi Aizawa
Shisa promotes head formation through the inhibition of receptor protein maturation for the caudalizing factors, Wnt and FGF.
Cell 2005;120(2):223-35.
2004: Takuya Murata; Kenryo Furushima; Mariko Hirano; Hiroshi Kiyonari; Miwa Nakamura; Yoko Suda; Shinichi Aizawa
ang is a novel gene expressed in early neuroectoderm, but its null mutant exhibits no obvious phenotype.
Gene expression patterns : GEP 2004;5(2):171-8.
2004: Daisuke Kurokawa; Hiroshi Kiyonari; Rika Nakayama; Chiharu Kimura-Yoshida; Isao Matsuo; Shinichi Aizawa
Regulation of Otx2 expression and its functions in mouse forebrain and midbrain.
Development (Cambridge, England) 2004;131(14):3319-31.
2004: Daisuke Kurokawa; Nobuyoshi Takasaki; Hiroshi Kiyonari; Rika Nakayama; Chiharu Kimura-Yoshida; Isao Matsuo; Shinichi Aizawa
Regulation of Otx2 expression and its functions in mouse epiblast and anterior neuroectoderm.
Development (Cambridge, England) 2004;131(14):3307-17.
2004: Chiharu Kimura-Yoshida; Kuniko Kitajima; izumi oda; E Tian; Misao Suzuki; Masayuki Yamamoto; Tohru Suzuki; Makoto Kobayashi; Shinichi Aizawa; Isao Matsuo
Characterization of the pufferfish Otx2 cis-regulators reveals evolutionarily conserved genetic mechanisms for vertebrate head specification.
Development (Cambridge, England) 2004;131(1):57-71.
2002: Takuichiro Hide; Jun Hatakeyama; Chiharu Kimura-Yoshida; E Tian; Naoki Takeda; Yukitaka Ushio; Toshihiko Shiroishi; Shinichi Aizawa; Isao Matsuo
Genetic modifiers of otocephalic phenotypes in Otx2 heterozygous mutant mice.
Development (Cambridge, England) 2002;129(18):4347-57.