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Jean Wang

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Alexandre P A Theocharides; Nico van Rooijen; Po-Yan Cheng; Jayne S Danska; John E Dick; Jenny M Ho; Liqing Jin; Andrei V Malko; Mark D Minden; Armando G Poeppl; Tatiana K Prasolava; Jean C Y Wang
Disruption of SIRPα signaling in macrophages eliminates human acute myeloid leukemia stem cells in xenografts.
Tino Schenk; Jean C Y Wang; Patrick M Woster; Alan Burnett; Robert A Casero; Weihsu Claire Chen; John E Dick; Martin Dugas; Stefanie Göllner; Katja Hebestreit; Louise Howell; Liqing Jin; Hans-Ulrich Klein; Laurence Marton; Ken Mills; Mark D Minden; Carsten Müller-Tidow; Kevin Petrie; Andreea C Popescu; Arthur Zelent
Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia.
Marko Skrtić; Paul Spagnuolo; Shrivani Sriskanthadevan; Jean C Y Wang; Xiaoming Wang; Zezhou Wang; Jeffery Wrana; Justyna Bartoszko; Jessie H Cameron; Alessandro Datti; John E Dick; Connie J Eaves; Yanina Eberhard; Marinella Gebbia; Guri Giaever; Marcela Gronda; Keith Humphries; Rose Hurren; Bozhena Jhas; Yulia Jitkova; Troy Ketela; Courteney K Lai; Neil Maclean; Mark D Minden; Jason Moffat; Corey Nislow; Brian H Robinson; Angela C Rutledge; Aaron D Schimmer
Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia.

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All Publications

2012: Alexandre P A Theocharides; Nico van Rooijen; Po-Yan Cheng; Jayne S Danska; John E Dick; Jenny M Ho; Liqing Jin; Andrei V Malko; Mark D Minden; Armando G Poeppl; Tatiana K Prasolava; Jean C Y Wang
Disruption of SIRPα signaling in macrophages eliminates human acute myeloid leukemia stem cells in xenografts.
The Journal of experimental medicine 2012;209(10):1883-99.
2012: Tino Schenk; Jean C Y Wang; Patrick M Woster; Alan Burnett; Robert A Casero; Weihsu Claire Chen; John E Dick; Martin Dugas; Stefanie Göllner; Katja Hebestreit; Louise Howell; Liqing Jin; Hans-Ulrich Klein; Laurence Marton; Ken Mills; Mark D Minden; Carsten Müller-Tidow; Kevin Petrie; Andreea C Popescu; Arthur Zelent
Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia.
Nature medicine 2012;18(4):605-11.
2011: Marko Skrtić; Paul Spagnuolo; Shrivani Sriskanthadevan; Jean C Y Wang; Xiaoming Wang; Zezhou Wang; Jeffery Wrana; Justyna Bartoszko; Jessie H Cameron; Alessandro Datti; John E Dick; Connie J Eaves; Yanina Eberhard; Marinella Gebbia; Guri Giaever; Marcela Gronda; Keith Humphries; Rose Hurren; Bozhena Jhas; Yulia Jitkova; Troy Ketela; Courteney K Lai; Neil Maclean; Mark D Minden; Jason Moffat; Corey Nislow; Brian H Robinson; Angela C Rutledge; Aaron D Schimmer
Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia.
Cancer cell 2011;20(5):674-88.
2011: Faiyaz Notta; Charles G Mullighan; Jean C Y Wang; Armando Poeppl; Sergei Doulatov; Letha A Phillips; Jing Ma; Mark D Minden; James R Downing; John E Dick
Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells.
Nature 2011;469(7330):362-7.
2010: Jean C Y Wang
Good cells gone bad: the cellular origins of cancer.
Trends in molecular medicine 2010;16(3):145-51.
2007: James A Kennedy; Frédéric Barabé; Armando G Poeppl; Jean C Y Wang; John E Dick
Comment on "Tumor growth need not be driven by rare cancer stem cells".
Science (New York, N.Y.) 2007;318(5857):1722; author reply 1722.
2007: Katsuto Takenaka; Tatiana K Prasolava; Jean C Y Wang; Steven M Mortin-Toth; Sam Khalouei; Olga I Gan; John E Dick; Jayne S Danska
Polymorphism in Sirpa modulates engraftment of human hematopoietic stem cells.
Nature immunology 2007;8(12):1313-23.
2007: Jean C Y Wang
Evaluating therapeutic efficacy against cancer stem cells: new challenges posed by a new paradigm.
Cell stem cell 2007;1(5):497-501.
2007: Seth J Corey; Mark D Minden; Dwayne Barber; Andrew Lamb; Jean C Y Wang; Aaron D Schimmer
Myelodysplastic syndromes: the complexity of stem-cell diseases.
Nature reviews. Cancer 2007;7(2):118-29.
2006: Joby L McKenzie; Olga I Gan; Monica Doedens; Jean C Y Wang; John E Dick
Individual stem cells with highly variable proliferation and self-renewal properties comprise the human hematopoietic stem cell compartment.
Nature immunology 2006;7(11):1225-33.
2005: Jean C Y Wang; John E Dick
Cancer stem cells: lessons from leukemia.
Trends in cell biology 2005;15(9):494-501.
2004: Jennifer K Warner; Jean C Y Wang; Kristin J Hope; Liqing Jin; John E Dick
Concepts of human leukemic development.
Oncogene 2004;23(43):7164-77.
2000: Shiaw-Yih Lin; Weiya Xia; Jean C Y Wang; Ka Yin Kwong; Bill Spohn; Yong Wen; Richard G Pestell; Mien-Chie Hung
Beta-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(8):4262-6.
1999: Olga I Gan; Craig Dorrell; DS Pereira; C Y Ito; Jean C Y Wang; John E Dick
Characterization and retroviral transduction of an early human lymphomyeloid precursor assayed in nonswitched long-term culture on murine stroma.
Experimental hematology 1999;27(6):1097-106.
1999: D Bonnet; Mickie Bhatia; Jean C Y Wang; U Kapp; John E Dick
Cytokine treatment or accessory cells are required to initiate engraftment of purified primitive human hematopoietic cells transplanted at limiting doses into NOD/SCID mice.
Bone marrow transplantation 1999;23(3):203-9.
1998: Jean C Y Wang; T Lapidot; Johanne Cashman; Monica Doedens; L Addy; D Robert Sutherland; R Nayar; P Laraya; Mark D Minden; A Keating; Allen Eaves; Connie J Eaves; John E Dick
High level engraftment of NOD/SCID mice by primitive normal and leukemic hematopoietic cells from patients with chronic myeloid leukemia in chronic phase.
Blood 1998;91(7):2406-14.
1997: Mickie Bhatia; D Bonnet; U Kapp; Jean C Y Wang; Barbara Murdoch; John E Dick
Quantitative analysis reveals expansion of human hematopoietic repopulating cells after short-term ex vivo culture.
The Journal of experimental medicine 1997;186(4):619-24.
1997: Johanne Cashman; T Lapidot; Jean C Y Wang; Monica Doedens; L D Shultz; Peter M Lansdorp; John E Dick; Connie J Eaves
Kinetic evidence of the regeneration of multilineage hematopoiesis from primitive cells in normal human bone marrow transplanted into immunodeficient mice.
Blood 1997;89(12):4307-16.
1997: Jean C Y Wang; Monica Doedens; John E Dick
Primitive human hematopoietic cells are enriched in cord blood compared with adult bone marrow or mobilized peripheral blood as measured by the quantitative in vivo SCID-repopulating cell assay.
Blood 1997;89(11):3919-24.
1997: Mickie Bhatia; Jean C Y Wang; U Kapp; D Bonnet; John E Dick
Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(10):5320-5.
1997: John E Dick; Mickie Bhatia; Olga I Gan; U Kapp; Jean C Y Wang
Assay of human stem cells by repopulation of NOD/SCID mice.
Stem cells (Dayton, Ohio) 1997;15 Suppl 1():199-203; discussion 204-7.
1996: A Larochelle; J Vormoor; Helmut Hanenberg; Jean C Y Wang; Mickie Bhatia; Tsvee Lapidot; T Moritz; Barbara Murdoch; X L Xiao; I Kato; David A Williams; John E Dick
Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: implications for gene therapy.
Nature medicine 1996;2(12):1329-37.