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Jean Wang

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Jinbo Han; Michael E Ramirez; Anil Sadarangani; Rossana C Soletti; Priya Sridevi; Helena L Borges; Lars Eckmann; Jean Y J Wang
Nuclear expression of β-catenin promotes RB stability and resistance to TNF-induced apoptosis in colon cancer cells.
Jinbo Han; Kirsten J Ludwig; Michael Ramirez; Priya Sridevi; Jean Y J Wang
β-Catenin-dependent lysosomal targeting of internalized tumor necrosis factor-α suppresses caspase-8 activation in apoptosis-resistant colon cancer cells.
Jean Y J Wang
Checking before changing: cell cycle checkpoints inhibit muscle differentiation.

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2013: Jinbo Han; Michael E Ramirez; Anil Sadarangani; Rossana C Soletti; Priya Sridevi; Helena L Borges; Lars Eckmann; Jean Y J Wang
Nuclear expression of β-catenin promotes RB stability and resistance to TNF-induced apoptosis in colon cancer cells.
Molecular cancer research : MCR 2013;11(3):207-18.
2013: Jinbo Han; Kirsten J Ludwig; Michael Ramirez; Priya Sridevi; Jean Y J Wang
β-Catenin-dependent lysosomal targeting of internalized tumor necrosis factor-α suppresses caspase-8 activation in apoptosis-resistant colon cancer cells.
Molecular biology of the cell 2013;24(4):465-73.
2011: Jean Y J Wang
Checking before changing: cell cycle checkpoints inhibit muscle differentiation.
Cell cycle (Georgetown, Tex.) 2011;10(19):3234-5.
2011: Ryan J Bourgo; Adam Ertel; Jacqueline Bergseid; A Kathleen McClendon; Chellappagounder Thangavel; Jean Y J Wang; Ludwig Wilkens; Agnieszka Witkiewicz; Erik S Knudsen
RB restricts DNA damage-initiated tumorigenesis through an LXCXE-dependent mechanism of transcriptional control.
Molecular cell 2011;43(4):663-72.
2011: Olivier De Wever; Marc Bracke; Christian Gespach; Jean-Claude Michalski; Radia Ouelaa-Benslama; Joëlle Sobczak-Thépot; Dwayne G Stupack; Anne-Sophie Vercoutter-Edouart; Jean Y J Wang; Shahin Emami
Priming and potentiation of DNA damage response by fibronectin in human colon cancer cells and tumor-derived myofibroblasts.
International journal of oncology 2011;39(2):393-400.
2011: Anna Innocenzi; Lucia Latella; Graziella Messina; Marta Simonatto; Fabrizia Marullo; Libera Berghella; Coralie Poizat; Chih-Wen Shu; Jean Y J Wang; Pier Lorenzo Puri; Giulio Cossu
An evolutionarily acquired genotoxic response discriminates MyoD from Myf5, and differentially regulates hypaxial and epaxial myogenesis.
EMBO reports 2011;12(2):164-71.
2011: Zeitlin Samantha; Brian R Chapados; Norman M Baker; Caroline Tai; Geir Slupphaug; Jean Y J Wang
Uracil DNA N-glycosylase promotes assembly of human centromere protein A.
PloS one 2011;6(3):e17151.
2011: Martin Preyer; Paolo Vigneri; Jean Y J Wang
Interplay between kinase domain autophosphorylation and F-actin binding domain in regulating imatinib sensitivity and nuclear import of BCR-ABL.
PloS one 2011;6(2):e17020.
2010: Yong Jiang; Guangli Suo; Anil Sadarangani; Bryan Cowan; Jean Y J Wang
Expression profiling of protein tyrosine kinases and their ligand activators in leiomyoma uteri.
Systems biology in reproductive medicine 2010;56(4):318-26.
2010: Erik S Knudsen; Jean Y J Wang
Targeting the RB-pathway in cancer therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(4):1094-9.
2009: Guangli Suo; Yong Jiang; Bryan Cowan; Jean Y J Wang
Platelet-derived growth factor C is upregulated in human uterine fibroids and regulates uterine smooth muscle cell growth.
Biology of reproduction 2009;81(4):749-58.
2009: Samantha G Zeitlin; Norman M Baker; Brian R Chapados; Evi Soutoglou; Jean Y J Wang; Michael W Berns; Don W Cleveland
Double-strand DNA breaks recruit the centromeric histone CENP-A.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(37):15762-7.
2009: Guangli Suo; Anil Sadarangani; Babbette Lamarca; Bryan Cowan; Jean Y J Wang
Murine xenograft model for human uterine fibroids: an in vivo imaging approach.
Reproductive sciences (Thousand Oaks, Calif.) 2009;16(9):827-42.
2009: Sarah M Francis; Jacqueline Bergsied; Christian E Isaac; Courtney H Coschi; Alison L Martens; Carlo V Hojilla; Subrata Chakrabarti; Gabriel E Dimattia; Rama Khoka; Jean Y J Wang; Frederick A Dick
A functional connection between pRB and transforming growth factor beta in growth inhibition and mammary gland development.
Molecular and cellular biology 2009;29(16):4455-66.
2009: Scott A Stuart; Jean Y J Wang
Ionizing radiation induces ATM-independent degradation of p21Cip1 in transformed cells.
The Journal of biological chemistry 2009;284(22):15061-70.
2009: Scott A Stuart; Yosuke Minami; Jean Y J Wang
The CML stem cell: evolution of the progenitor.
Cell cycle (Georgetown, Tex.) 2009;8(9):1338-43.
2009: Vera Huang; Xin Lu; Yong Jiang; Jean Y J Wang
Effect of hydroxyurea on the promoter occupancy profiles of tumor suppressor p53 and p73.
BMC biology 2009;7():35.
2008: Akihiro Abe; Yosuke Minami; Fumihiko Hayakawa; Kunio Kitamura; Yuka Nomura; Makoto Murata; Akira Katsumi; Hitoshi Kiyoi; Catriona H M Jamieson; Jean Y J Wang; Tomoki Naoe
Retention but significant reduction of BCR-ABL transcript in hematopoietic stem cells in chronic myelogenous leukemia after imatinib therapy.
International journal of hematology 2008;88(5):471-5.
2008: Yosuke Minami; Scott A Stuart; Tomokatsu Ikawa; Yong Jiang; Asoka Banno; Irina C Hunton; Dennis J Young; Tomoki Naoe; Cornelis Murre; Catriona H M Jamieson; Jean Y J Wang
BCR-ABL-transformed GMP as myeloid leukemic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(46):17967-72.
2008: Xiaodong Huang; Diana Wu; Hua Jin; Stupack Dwayne; Jean Y J Wang
Induction of cell retraction by the combined actions of Abl-CrkII and Rho-ROCK1 signaling.
The Journal of cell biology 2008;183(4):711-23.
2008: Ivana Marinovic-Terzic; Atsuko Yoshioka-Yamashita; Hideki Shimodaira; Elena Avdievich; Irina C Hunton; Richard D Kolodner; Winfried Edelmann; Jean Y J Wang
Apoptotic function of human PMS2 compromised by the nonsynonymous single-nucleotide polymorphic variant R20Q.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(37):13993-8.
2008: Xiaodong Huang; Jean Y J Wang; Xin Lu
Systems analysis of quantitative shRNA-library screens identifies regulators of cell adhesion.
BMC systems biology 2008;2():49.
2008: Helena Lobo Borges; Rafael Linden; Jean Y J Wang
DNA damage-induced cell death: lessons from the central nervous system.
Cell research 2008;18(1):17-26.
2007: Unyoung Kim; Chih-Wen Shu; Karen Y Dane; Patrick S Daugherty; Jean Y J Wang; Hyongsok T Soh
Selection of mammalian cells based on their cell-cycle phase using dielectrophoresis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(52):20708-12.
2007: Xiaodong Huang; Anja Masselli; Steven M Frisch; Irina C Hunton; Yong Jiang; Jean Y J Wang
Blockade of tumor necrosis factor-induced Bid cleavage by caspase-resistant Rb.
The Journal of biological chemistry 2007;282(40):29401-13.
2007: Hua Jin; Jean Y J Wang
Abl tyrosine kinase promotes dorsal ruffles but restrains lamellipodia extension during cell spreading on fibronectin.
Molecular biology of the cell 2007;18(10):4143-54.
2006: Zehan Chen; Zhan Xiao; Wen-Zhen Gu; John Xue; Mai-Ha Bui; Peter Kovar; Gaoquan Li; Gary Wang; Zhi-Fu Tao; Yunsong Tong; Nan-Horng Lin; Hing L Sham; Jean Y J Wang; Thomas J Sowin; Saul H Rosenberg; Haiying Zhang
Selective Chk1 inhibitors differentially sensitize p53-deficient cancer cells to cancer therapeutics.
International journal of cancer. Journal international du cancer 2006;119(12):2784-94.
2006: Connie Chao; Zhiqun Wu; Sharlyn J Mazur; Helena Borges; Matteo Rossi; Tongxiang Lin; Jean Y J Wang; Carl W Anderson; Ettore Appella; Yang Xu
Acetylation of mouse p53 at lysine 317 negatively regulates p53 apoptotic activities after DNA damage.
Molecular and cellular biology 2006;26(18):6859-69.
2006: Jean Y J Wang
Eph tumour suppression: the dark side of Gleevec.
Nature cell biology 2006;8(8):785-6.
2006: Jean Y J Wang; Winfried Edelmann
Mismatch repair proteins as sensors of alkylation DNA damage.
Cancer cell 2006;9(6):417-8.
2006: B Nelson Chau; Chris W Pan; Jean Y J Wang
Separation of anti-proliferation and anti-apoptotic functions of retinoblastoma protein through targeted mutations of its A/B domain.
PloS one 2006;1():e82.
2005: Helena L Borges; Jeff Bird; Katherine Wasson; Robert Cardiff; Nissi M Varki; Lars Eckmann; Jean Y J Wang
Tumor promotion by caspase-resistant retinoblastoma protein.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(43):15587-92.
2005: Pamela J Woodring; Tony Hunter; Jean Y J Wang
Mitotic phosphorylation rescues Abl from F-actin-mediated inhibition.
The Journal of biological chemistry 2005;280(11):10318-25.
2005: Soheil Naderi; Jean Y J Wang; Tung-Ti Chen; Kristine B Gutzkow; Heidi Kiil Blomhoff
cAMP-mediated inhibition of DNA replication and S phase progression: involvement of Rb, p21Cip1, and PCNA.
Molecular biology of the cell 2005;16(3):1527-42.
2005: Chun-Ying Li; Jiangyu Zhu; Jean Y J Wang
Ectopic expression of p73alpha, but not p73beta, suppresses myogenic differentiation.
The Journal of biological chemistry 2005;280(3):2159-64.
2004: Pamela J Woodring; Jill Meisenhelder; Sam A Johnson; Guo-Lei Zhou; Jeffrey Field; Kavita Shah; Friedhelm Bladt; Tony Pawson; Masaru Niki; Pier Paolo Pandolfi; Jean Y J Wang; Tony Hunter
c-Abl phosphorylates Dok1 to promote filopodia during cell spreading.
The Journal of cell biology 2004;165(4):493-503.
2004: B Nelson Chau; Tung-Ti Chen; Yisong Y Wan; James DeGregori; Jean Y J Wang
Tumor necrosis factor alpha-induced apoptosis requires p73 and c-ABL activation downstream of RB degradation.
Molecular and cellular biology 2004;24(10):4438-47.
2004: Jean Y J Wang; Sarah K Cho
Coordination of repair, checkpoint, and cell death responses to DNA damage.
Advances in protein chemistry 2004;69():101-35.
2004: Jiangyu Zhu; Jean Y J Wang
Death by Abl: a matter of location.
Current topics in developmental biology 2004;59():165-92.
2004: Jean Y J Wang
Controlling Abl: auto-inhibition and co-inhibition?
Nature cell biology 2004;6(1):3-7.
2003: Tony Truong; Guizhen Sun; Michael Doorly; Jean Y J Wang; Martin A Schwartz
Modulation of DNA damage-induced apoptosis by cell adhesion is independently mediated by p53 and c-Abl.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(18):10281-6.
2003: Barbara Guerra; Olaf-Georg Issinger; Jean Y J Wang
Modulation of human checkpoint kinase Chk1 by the regulatory beta-subunit of protein kinase CK2.
Oncogene 2003;22(32):4933-42.
2003: Veronica Vella; Jiangyu Zhu; Francesco Frasca; Chun-Ying Li; Paolo Vigneri; Riccardo Vigneri; Jean Y J Wang
Exclusion of c-Abl from the nucleus restrains the p73 tumor suppression function.
The Journal of biological chemistry 2003;278(27):25151-7.
2003: Pamela J Woodring; Tony Hunter; Jean Y J Wang
Regulation of F-actin-dependent processes by the Abl family of tyrosine kinases.
Journal of cell science 2003;116(Pt 13):2613-26.
2003: Hideki Shimodaira; Atsuko Yoshioka-Yamashita; Richard D Kolodner; Jean Y J Wang
Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(5):2420-5.
2003: B Nelson Chau; Jean Y J Wang
Coordinated regulation of life and death by RB.
Nature reviews. Cancer 2003;3(2):130-8.
2002: Pier Lorenzo Puri; Kunjan S Bhakta; Lauren D Wood; Antonio Costanzo; Jiangyu Zhu; Jean Y J Wang
A myogenic differentiation checkpoint activated by genotoxic stress.
Nature genetics 2002;32(4):585-93.
2002: B Nelson Chau; Helena Lobo Borges; Tung-Ti Chen; Anja Masselli; Irina C Hunton; Jean Y J Wang
Signal-dependent protection from apoptosis in mice expressing caspase-resistant Rb.
Nature cell biology 2002;4(10):757-65.
2002: Keding Cheng; Razelle Kurzrock; Xiangguo Qiu; Zeev Estrov; Stella Ku; Kim M Dulski; Jean Y J Wang; Moshe Talpaz
Reduced focal adhesion kinase and paxillin phosphorylation in BCR-ABL-transfected cells.
Cancer 2002;95(2):440-50.
2002: Maria Valeria Catani; Antonio Costanzo; Isabella Savini; Massimo Levrero; Vincenzo de Laurenzi; Jean Y J Wang; Gerry Melino; Luciana Avigliano
Ascorbate up-regulates MLH1 (Mut L homologue-1) and p73: implications for the cellular response to DNA damage.
The Biochemical journal 2002;364(Pt 2):441-7.
2002: Soheil Naderi; Irina C Hunton; Jean Y J Wang
Radiation dose-dependent maintenance of G(2) arrest requires retinoblastoma protein.
Cell cycle (Georgetown, Tex.) 2002;1(3):193-200.
2002: Pamela J Woodring; E David Litwack; Dennis D M O'Leary; Ginger R Lucero; Jean Y J Wang; Tony Hunter
Modulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extension.
The Journal of cell biology 2002;156(5):879-92.
2001: Jean Y J Wang; S W Ki
Choosing between growth arrest and apoptosis through the retinoblastoma tumour suppressor protein, Abl and p73.
Biochemical Society transactions 2001;29(Pt 6):666-73.
2001: Pier Lorenzo Puri; Simona Iezzi; Peter Stiegler; Tung-Ti Chen; R Louis Schiltz; George E O Muscat; Antonio Giordano; Larry Kedes; Jean Y J Wang; Vittorio Sartorelli
Class I histone deacetylases sequentially interact with MyoD and pRb during skeletal myogenesis.
Molecular cell 2001;8(4):885-97.
2001: Jun Sun; Ji Zhao; Martin A Schwartz; Jean Y J Wang; Therese Wiedmer; Peter J Sims
c-Abl tyrosine kinase binds and phosphorylates phospholipid scramblase 1.
The Journal of biological chemistry 2001;276(31):28984-90.
2001: Francesco Frasca; Paolo Vigneri; Veronica Vella; Riccardo Vigneri; Jean Y J Wang
Tyrosine kinase inhibitor STI571 enhances thyroid cancer cell motile response to Hepatocyte Growth Factor.
Oncogene 2001;20(29):3845-56.
2001: P Vigneri; Jean Y J Wang
Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR-ABL tyrosine kinase.
Nature medicine 2001;7(2):228-34.
2000: Jean Y J Wang
Regulation of cell death by the Abl tyrosine kinase.
Oncogene 2000;19(49):5643-50.
2000: Karen E Knudsen; D Booth; Soheil Naderi; Zvjezdana Sever-Chroneos; Anne F Fribourg; Irina C Hunton; James R Feramisco; Jean Y J Wang; Erik S Knudsen
RB-dependent S-phase response to DNA damage.
Molecular and cellular biology 2000;20(20):7751-63.
2000: Tung-Ti Chen; Jean Y J Wang
Establishment of irreversible growth arrest in myogenic differentiation requires the RB LXCXE-binding function.
Molecular and cellular biology 2000;20(15):5571-80.
2000: Zhiqun Wu; Pamela J Woodring; Kunjan S Bhakta; K Tamura; F Wen; James R Feramisco; Michael Karin; Jean Y J Wang; Pier Lorenzo Puri
p38 and extracellular signal-regulated kinases regulate the myogenic program at multiple steps.
Molecular and cellular biology 2000;20(11):3951-64.
2000: Pier Lorenzo Puri; Zhiqun Wu; Peilin Zhang; Lauren D Wood; Kunjan S Bhakta; J Han; James R Feramisco; Michael Karin; Jean Y J Wang
Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosarcoma cells.
Genes & development 2000;14(5):574-84.
2000: Jean Y J Wang; Richard D Kolodner
Keystone Symposia on Molecular and Cellular Biology: 'The molecular basis of cancer'. Organizers: Carol L. Prives and George F. Vande Woude, Taos, NM, 15-21 March 1999.
Biochimica et biophysica acta 2000;1470(1):R21-8.
1999: J G Gong; A Costanzo; H Q Yang; G Melino; William G Kaelin; M Levrero; Jean Y J Wang
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage.
Nature 1999;399(6738):806-9.
1999: R Baskaran; S R Escobar; Jean Y J Wang
Nuclear c-Abl is a COOH-terminal repeated domain (CTD)-tyrosine (CTD)-tyrosine kinase-specific for the mammalian RNA polymerase II: possible role in transcription elongation.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1999;10(6):387-96.
1999: A Nehmé; R Baskaran; S Nebel; D Fink; Stephen B Howell; Jean Y J Wang; RD Christen
Induction of JNK and c-Abl signalling by cisplatin and oxaliplatin in mismatch repair-proficient and -deficient cells.
British journal of cancer 1999;79(7-8):1104-10.
1998: Erik S Knudsen; C Buckmaster; Tung-Ti Chen; James R Feramisco; Jean Y J Wang
Inhibition of DNA synthesis by RB: effects on G1/S transition and S-phase progression.
Genes & development 1998;12(15):2278-92.
1998: LL Whitaker; H Su; R Baskaran; Erik S Knudsen; Jean Y J Wang
Growth suppression by an E2F-binding-defective retinoblastoma protein (RB): contribution from the RB C pocket.
Molecular and cellular biology 1998;18(7):4032-42.
1998: S Taagepera; D McDonald; J E Loeb; LL Whitaker; A K McElroy; Jean Y J Wang; Thomas J Hope
Nuclear-cytoplasmic shuttling of C-ABL tyrosine kinase.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(13):7457-62.
1998: Erik S Knudsen; Jean Y J Wang
Hyperphosphorylated p107 and p130 bind to T-antigen: identification of a critical regulatory sequence present in RB but not in p107/p130.
Oncogene 1998;16(13):1655-63.
1997: Pier Lorenzo Puri; Vittorio Sartorelli; XJ Yang; Yasuo Hamamori; Vasily Ogryzko; Bruce H Howard; Larry Kedes; Jean Y J Wang; Adolf Graessmann; Yoshihiro Nakatani; Massimo Levrero
Differential roles of p300 and PCAF acetyltransferases in muscle differentiation.
Molecular cell 1997;1(1):35-45.
1997: W Arap; Erik S Knudsen; Duane A Sewell; David Sidransky; Jean Y J Wang; H J Huang; Webster K Cavenee
Functional analysis of wild-type and malignant glioma derived CDKN2Abeta alleles: evidence for an RB-independent growth suppressive pathway.
Oncogene 1997;15(17):2013-20.
1997: J R McWhirter; Jean Y J Wang
Effect of Bcr sequences on the cellular function of the Bcr-Abl oncoprotein.
Oncogene 1997;15(14):1625-34.
1997: Erik S Knudsen; Jean Y J Wang
Dual mechanisms for the inhibition of E2F binding to RB by cyclin-dependent kinase-mediated RB phosphorylation.
Molecular and cellular biology 1997;17(10):5771-83.
1997: A Nehmé; R Baskaran; Stefan Aebi; D Fink; S Nebel; B Cenni; Jean Y J Wang; Stephen B Howell; RD Christen
Differential induction of c-Jun NH2-terminal kinase and c-Abl kinase in DNA mismatch repair-proficient and -deficient cells exposed to cisplatin.
Cancer research 1997;57(15):3253-7.
1997: R Baskaran; G G Chiang; T Mysliwiec; Gary Kruh; Jean Y J Wang
Tyrosine phosphorylation of RNA polymerase II carboxyl-terminal domain by the Abl-related gene product.
The Journal of biological chemistry 1997;272(30):18905-9.
1997: R Baskaran; L D Wood; LL Whitaker; Shilpy Sharma; SE Morgan; Y Xu; C Barlow; David Baltimore; A Wynshaw-Boris; Michael B Kastan; Jean Y J Wang
Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation.
Nature 1997;387(6632):516-9.
1997: X Tan; Seamus Martin; D R Green; Jean Y J Wang
Degradation of retinoblastoma protein in tumor necrosis factor- and CD95-induced cell death.
The Journal of biological chemistry 1997;272(15):9613-6.
1997: Mandri Obeyesekere; Erik S Knudsen; Jean Y J Wang; Stuart O Zimmerman
A mathematical model of the regulation of the G1 phase of Rb+/+ and Rb-/- mouse embryonic fibroblasts and an osteosarcoma cell line.
Cell proliferation 1997;30(3-4):171-94.
1997: W Arap; Erik S Knudsen; Jean Y J Wang; Webster K Cavenee; H J Huang
Point mutations can inactivate in vitro and in vivo activities of p16(INK4a)/CDKN2A in human glioma.
Oncogene 1997;14(5):603-9.
1997: Jean Y J Wang
Retinoblastoma protein in growth suppression and death protection.
Current opinion in genetics & development 1997;7(1):39-45.
1996: Jean M Lewis; R Baskaran; S Taagepera; M A Schwartz; Jean Y J Wang
Integrin regulation of c-Abl tyrosine kinase activity and cytoplasmic-nuclear transport.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(26):15174-9.
1996: Z G Liu; R Baskaran; E T Lea-Chou; L D Wood; Yan Chen; Michael Karin; Jean Y J Wang
Three distinct signalling responses by murine fibroblasts to genotoxic stress.
Nature 1996;384(6606):273-6.
1996: Yan Chen; Erik S Knudsen; Jean Y J Wang
The RB/p107/p130 phosphorylation pathway is not inhibited in rapamycin-induced G1-prolongation of NIH3T3 cells.
Oncogene 1996;13(8):1765-71.
1996: Y J Miao; Jean Y J Wang
Binding of A/T-rich DNA by three high mobility group-like domains in c-Abl tyrosine kinase.
The Journal of biological chemistry 1996;271(37):22823-30.
1996: Yan Chen; Erik S Knudsen; Jean Y J Wang
Cells arrested in G1 by the v-Abl tyrosine kinase do not express cyclin A despite the hyperphosphorylation of RB.
The Journal of biological chemistry 1996;271(33):19637-40.
1996: Karen E Knudsen; Erik S Knudsen; Jean Y J Wang; Suresh Subramani
p34cdc2 kinase activity is maintained upon activation of the replication checkpoint in Schizosaccharomyces pombe.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(16):8278-83.
1996: R Baskaran; G G Chiang; Jean Y J Wang
Identification of a binding site in c-Ab1 tyrosine kinase for the C-terminal repeated domain of RNA polymerase II.
Molecular and cellular biology 1996;16(7):3361-9.
1996: Erik S Knudsen; Jean Y J Wang
Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites.
The Journal of biological chemistry 1996;271(14):8313-20.
1996: M W Renshaw; E Lea-Chou; Jean Y J Wang
Rac is required for v-Abl tyrosine kinase to activate mitogenesis.
Current biology : CB 1996;6(1):76-83.
1995: P J Welch; Jean Y J Wang
Abrogation of retinoblastoma protein function by c-Abl through tyrosine kinase-dependent and -independent mechanisms.
Molecular and cellular biology 1995;15(10):5542-51.
1995: T S Huang; J Duyster; Jean Y J Wang
Biological response to phorbol ester determined by alternative G1 pathways.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(11):4793-7.
1995: M W Renshaw; J R McWhirter; Jean Y J Wang
The human leukemia oncogene bcr-abl abrogates the anchorage requirement but not the growth factor requirement for proliferation.
Molecular and cellular biology 1995;15(3):1286-93.
1995: J Duyster; R Baskaran; Jean Y J Wang
Src homology 2 domain as a specificity determinant in the c-Abl-mediated tyrosine phosphorylation of the RNA polymerase II carboxyl-terminal repeated domain.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(5):1555-9.
1995: P J Welch; Jean Y J Wang
Disruption of retinoblastoma protein function by coexpression of its C pocket fragment.
Genes & development 1995;9(1):31-46.
1994: Jean Y J Wang; J R McWhirter
Tyrosine-kinase-dependent signaling pathways.
Trends in cardiovascular medicine 1994;4(6):264-70.
1994: Jean Y J Wang
Nuclear protein tyrosine kinases.
Trends in biochemical sciences 1994;19(9):373-6.
1994: Jie Qiang Guo; J Y Lian; Y M Xian; M S Lee; Albert Deisseroth; Sanford A Stass; Richard E Champlin; Moshe Talpaz; Jean Y J Wang; Ralph B Arlinghaus
BCR-ABL protein expression in peripheral blood cells of chronic myelogenous leukemia patients undergoing therapy.
Blood 1994;83(12):3629-37.
1994: Jean Y J Wang; Erik S Knudsen; P J Welch
The retinoblastoma tumor suppressor protein.
Advances in cancer research 1994;64():25-85.
1993: J R McWhirter; D L Galasso; Jean Y J Wang
A coiled-coil oligomerization domain of Bcr is essential for the transforming function of Bcr-Abl oncoproteins.
Molecular and cellular biology 1993;13(12):7587-95.
1993: R Baskaran; M E Dahmus; Jean Y J Wang
Tyrosine phosphorylation of mammalian RNA polymerase II carboxyl-terminal domain.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(23):11167-71.
1993: P J Welch; Jean Y J Wang
A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle.
Cell 1993;75(4):779-90.
1993: J R McWhirter; Jean Y J Wang
An actin-binding function contributes to transformation by the Bcr-Abl oncoprotein of Philadelphia chromosome-positive human leukemias.
The EMBO journal 1993;12(4):1533-46.
1993: Jean Y J Wang
Abl tyrosine kinase in signal transduction and cell-cycle regulation.
Current opinion in genetics & development 1993;3(1):35-43.
1992: M W Renshaw; Edward T Kipreos; M R Albrecht; Jean Y J Wang
Oncogenic v-Abl tyrosine kinase can inhibit or stimulate growth, depending on the cell context.
The EMBO journal 1992;11(11):3941-51.
1992: Edward T Kipreos; Jean Y J Wang
Cell cycle-regulated binding of c-Abl tyrosine kinase to DNA.
Science (New York, N.Y.) 1992;256(5055):382-5.
1992: P J Welch; Jean Y J Wang
Coordinated synthesis and degradation of cdc2 in the mammalian cell cycle.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(7):3093-7.
1992: Jean Y J Wang
Modelling chronic myelogenous leukemia.
Current biology : CB 1992;2(2):70-2.
1991: Jie Qiang Guo; Jean Y J Wang; Ralph B Arlinghaus
Detection of BCR-ABL proteins in blood cells of benign phase chronic myelogenous leukemia patients.
Cancer research 1991;51(11):3048-51.
1991: B T Lin; S Gruenwald; Alex Morla; Wen-Hwa Lee; Jean Y J Wang
Retinoblastoma cancer suppressor gene product is a substrate of the cell cycle regulator cdc2 kinase.
The EMBO journal 1991;10(4):857-64.
1991: J R McWhirter; Jean Y J Wang
Activation of tyrosinase kinase and microfilament-binding functions of c-abl by bcr sequences in bcr/abl fusion proteins.
Molecular and cellular biology 1991;11(3):1553-65.
1990: Edward T Kipreos; Jean Y J Wang
Differential phosphorylation of c-Abl in cell cycle determined by cdc2 kinase and phosphatase activity.
Science (New York, N.Y.) 1990;248(4952):217-20.
1989: Phang-Lang Chen; P Scully; J Y Shew; Jean Y J Wang; Wen-Hwa Lee
Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation.
Cell 1989;58(6):1193-8.
1989: Alex Morla; G Draetta; D Beach; Jean Y J Wang
Reversible tyrosine phosphorylation of cdc2: dephosphorylation accompanies activation during entry into mitosis.
Cell 1989;58(1):193-203.
1988: M W Renshaw; M A Capozza; Jean Y J Wang
Differential expression of type-specific c-abl mRNAs in mouse tissues and cell lines.
Molecular and cellular biology 1988;8(10):4547-51.
1988: Jean Y J Wang
Antibodies for phosphotyrosine: analytical and preparative tool for tyrosyl-phosphorylated proteins.
Analytical biochemistry 1988;172(1):1-7.
1988: Alex Morla; J Schreurs; A Miyajima; Jean Y J Wang
Hematopoietic growth factors activate the tyrosine phosphorylation of distinct sets of proteins in interleukin-3-dependent murine cell lines.
Molecular and cellular biology 1988;8(5):2214-8.
1988: Edward T Kipreos; Jean Y J Wang
Reversible dependence on growth factor interleukin-3 in myeloid cells expressing temperature sensitive v-abl oncogene.
Oncogene research 1988;2(3):277-84.
1988: Jean Y J Wang
Negative regulation of c-abl tyrosine kinase by its variable N-terminal amino acids.
Oncogene research 1988;3(3):293-8.