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Lai-Xi Wang

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Genes & Molecular Sequences

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Glycosylation

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TOP 3
Joseph V Lomino; Andreas Naegeli; Jared Orwenyo; Markus Aebi; Mohammed N Amin; Lai-Xi Wang
A two-step enzymatic glycosylation of polypeptides with complex N-glycans.
Helen Wang; Aditi Banerjee; Wei Huang; Jared Orwenyo; Gerardo Vasta; Lai-Xi Wang
Design and synthesis of glycoprotein-based multivalent glyco-ligands for influenza hemagglutinin and human galectin-3.
Wei Song; Lai-Xi Wang; Huaxi Xu; Xifeng Yang; Igor C Almeida; Jieqing Chen; Elizabeth S Delyria; Wei Huang; Nuhad Ibrahim; Jun Soo Lee; Yunsen Li; Hongzhou Lu; Katja Michael; Elizabeth A Mittendorf; Jin Qu; Laszlo G Radvanyi; Silas P Rodrigues; Jeremy A Ross; Nathaniel S Schocker; Yinqiang Shi; Dapeng Zhou
MUC1 glycopeptide epitopes predicted by computational glycomics.

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All Publications

2013: Joseph V Lomino; Andreas Naegeli; Jared Orwenyo; Markus Aebi; Mohammed N Amin; Lai-Xi Wang
A two-step enzymatic glycosylation of polypeptides with complex N-glycans.
Bioorganic & medicinal chemistry 2013;21(8):2262-70.
2013: Helen Wang; Aditi Banerjee; Wei Huang; Jared Orwenyo; Gerardo Vasta; Lai-Xi Wang
Design and synthesis of glycoprotein-based multivalent glyco-ligands for influenza hemagglutinin and human galectin-3.
Bioorganic & medicinal chemistry 2013;21(7):2037-44.
2012: Wei Song; Lai-Xi Wang; Huaxi Xu; Xifeng Yang; Igor C Almeida; Jieqing Chen; Elizabeth S Delyria; Wei Huang; Nuhad Ibrahim; Jun Soo Lee; Yunsen Li; Hongzhou Lu; Katja Michael; Elizabeth A Mittendorf; Jin Qu; Laszlo G Radvanyi; Silas P Rodrigues; Jeremy A Ross; Nathaniel S Schocker; Yinqiang Shi; Dapeng Zhou
MUC1 glycopeptide epitopes predicted by computational glycomics.
International journal of oncology 2012;41(6):1977-84.
2012: Wei Huang; Christian Toonstra; Shu-Quan Fan; John Giddens; Lai-Xi Wang
Chemoenzymatic glycoengineering of intact IgG antibodies for gain of functions.
Journal of the American Chemical Society 2012;134(29):12308-18.
2012: Alan S Cross; Chiguang Feng; Sergei Atamas; Wei Guang; Wei Huang; Sang Won Hyun; Erik Lillehoj; Anguo Liu; Irina G Luzina; Alba Miranda-Ribera; Chinh Nguyen; Antonino Passaniti; Adam C Puché; William S Twaddell; Lai-Xi Wang; Lei Zhang; Simeon E Goldblum
NEU1 and NEU3 sialidase activity expressed in human lung microvascular endothelia: NEU1 restrains endothelial cell migration, whereas NEU3 does not.
The Journal of biological chemistry 2012;287(19):15966-80.
2012: Shu-Quan Fan; Wei Huang; Lai-Xi Wang
Remarkable transglycosylation activity of glycosynthase mutants of endo-D, an endo-β-N-acetylglucosaminidase from Streptococcus pneumoniae.
The Journal of biological chemistry 2012;287(14):11272-81.
2012: Erik Lillehoj; Anguo Liu; Irina G Luzina; Chinh Nguyen; Antonino Passaniti; Adam C Puché; William S Twaddell; Lai-Xi Wang; Lei Zhang; Sergei Atamas; Alan S Cross; Chiguang Feng; Wei Guang; Sang Won Hyun; Simeon E Goldblum
NEU1 sialidase expressed in human airway epithelia regulates epidermal growth factor receptor (EGFR) and MUC1 protein signaling.
The Journal of biological chemistry 2012;287(11):8214-31.
2012: Lai-Xi Wang; Joseph V Lomino
Emerging technologies for making glycan-defined glycoproteins.
ACS chemical biology 2012;7(1):110-22.
2011: Jason S McLellan; Zhi-Yong Yang; Mark K Louder; Jason Gorman; Doyung Lee; Stephen D Schmidt; John A Crump; John R Mascola; Tongqing Zhou; Kaifan Dai; Andrew B Ward; Sanjay Phogat; Lai-Xi Wang; Syed Shahzad-ul-Hussan; Robert Louder; Jean-Philippe Julien; Mattia Bonsignori; Wayne C Koff; Robert Pejchal; Noel E Sam; Richard Wyatt; Marie Pancera; Jared Orwenyo; Reza Khayat; Carole A Bewley; Mallika Sastry; Laura M Walker; Chris Carrico; Baoshan Zhang; Ivelin Georgiev; Stephanie Moquin; Gwo-Yu Chuang; Young Do Kwon; James Arthos; Devan Diwanji; Sijy O'Dell; Yongping Yang; Ian A Wilson; Saidi H Kapiga; Dennis R Burton; Jiang Zhu; Gary Nabel; William R Schief; Jeffrey C Boyington; Nikita Patel; Barton F Haynes; Peter D Kwong
Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature 2011;480(7377):336-43.
2011: Guozhang Zou; QIANG YANG; Wei Huang; Cishan Li; Hirofumi Ochiai; Lai-Xi Wang
Chemoenzymatic synthesis and Fcγ receptor binding of homogeneous glycoforms of antibody Fc domain. Presence of a bisecting sugar moiety enhances the affinity of Fc to FcγIIIa receptor.
Journal of the American Chemical Society 2011;133(46):18975-91.
2011: Yongjun Li; Haiyan Qiao; Hongda Wang; Lai-Xi Wang; Chunyan Xing; Bailin Zhang; Jing Zhang; Jilin Tang
Molecular recognition force spectroscopy of a specific lectin-carbohydrate interaction at single-molecule level.
Journal of structural biology 2011;176(1):46-51.
2011: Mohammed N Amin; Wei Huang; Rahman M Mizanur; Lai-Xi Wang
Convergent synthesis of homogeneous Glc1Man9GlcNAc2-protein and derivatives as ligands of molecular chaperones in protein quality control.
Journal of the American Chemical Society 2011;133(36):14404-17.
2011: Wei Huang; Jie Li; Lai-Xi Wang
Unusual transglycosylation activity of Flavobacterium meningosepticum endoglycosidases enables convergent chemoenzymatic synthesis of core fucosylated complex N-glycopeptides.
Chembiochem : a European journal of chemical biology 2011;12(6):932-41.
2011: Dapeng Zhou; Steven B Levery; Fong-Fu Hsu; Peng G Wang; Susann Teneberg; Igor Almeida; Yunsen Li; Huaxi Xu; Lai-Xi Wang; Chengfeng Xia; Nuhad K Ibrahim; Katja Michael
Immunologic mapping of glycomes: implications for cancer diagnosis and therapy.
Frontiers in bioscience (Scholar edition) 2011;3():1520-32.
2010: Nicholas M Stamatos; Ivan Carubelli; Diantha van de Vlekkert; Erik J Bonten; Nadia Papini; Chiguang Feng; Bruno Venerando; Alessandra d'Azzo; Alan S Cross; Lai-Xi Wang; Peter J Gomatos
LPS-induced cytokine production in human dendritic cells is regulated by sialidase activity.
Journal of leukocyte biology 2010;88(6):1227-39.
2010: Wei Huang; Xinyu Zhang; Tongzhong Ju; Richard D Cummings; Lai-Xi Wang
Expeditious chemoenzymatic synthesis of CD52 glycopeptide antigens.
Organic & biomolecular chemistry 2010;8(22):5224-33.
2010: Midori Umekawa; Takayuki Higashiyama; Yurie Koga; Tomonari Tanaka; Masato Noguchi; Atsushi Kobayashi; Shin-Ichiro Shoda; Wei Huang; Lai-Xi Wang; Hisashi Ashida; Kenji Yamamoto
Efficient transfer of sialo-oligosaccharide onto proteins by combined use of a glycosynthase-like mutant of Mucor hiemalis endoglycosidase and synthetic sialo-complex-type sugar oxazoline.
Biochimica et biophysica acta 2010;1800(11):1203-9.
2010: Wei Huang; QIANG YANG; Midori Umekawa; Kenji Yamamoto; Lai-Xi Wang
Arthrobacter endo-beta-N-acetylglucosaminidase shows transglycosylation activity on complex-type N-glycan oxazolines: one-pot conversion of ribonuclease B to sialylated ribonuclease C.
Chembiochem : a European journal of chemical biology 2010;11(10):1350-5.
2010: Cory L Brooks; Andrea Schietinger; Svetlana N Borisova; Peter Kufer; Mark Okon; Tomoko Hirama; C Roger MacKenzie; Lai-Xi Wang; Hans Schreiber; Stephen V Evans
Antibody recognition of a unique tumor-specific glycopeptide antigen.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(22):10056-61.
2010: QIANG YANG; Cishan Li; Yadong Wei; Wei Huang; Lai-Xi Wang
Expression, glycoform characterization, and antibody-binding of HIV-1 V3 glycopeptide domain fused with human IgG1-Fc.
Bioconjugate chemistry 2010;21(5):875-83.
2010: Flavio Schwarz; Wei Huang; Cishan Li; Benjamin L Schulz; Christian Lizak; Alessandro Palumbo; Shin Numao; Dario Neri; Markus Aebi; Lai-Xi Wang
A combined method for producing homogeneous glycoproteins with eukaryotic N-glycosylation.
Nature chemical biology 2010;6(4):264-6.
2010: Midori Umekawa; Cishan Li; Takayuki Higashiyama; Wei Huang; Hisashi Ashida; Kenji Yamamoto; Lai-Xi Wang
Efficient glycosynthase mutant derived from Mucor hiemalis endo-beta-N-acetylglucosaminidase capable of transferring oligosaccharide from both sugar oxazoline and natural N-glycan.
The Journal of biological chemistry 2010;285(1):511-21.
2009: Wei Huang; Denong Wang; Masao Yamada; Lai-Xi Wang
Chemoenzymatic synthesis and lectin array characterization of a class of N-glycan clusters.
Journal of the American Chemical Society 2009;131(49):17963-71.
2009: Lai-Xi Wang; Wei Huang
Enzymatic transglycosylation for glycoconjugate synthesis.
Current opinion in chemical biology 2009;13(5-6):592-600.
2009: Lai-Xi Wang
Expanding the repertoire of glycosynthases.
Chemistry & biology 2009;16(10):1026-7.
2009: Xiao-Yang Zhu; Bryan Holtz; Yini Wang; Lai-Xi Wang; Paul E Orndorff; Athena Guo
Quantitative glycomics from fluidic glycan microarrays.
Journal of the American Chemical Society 2009;131(38):13646-50.
2009: Wei Huang; Stan Groothuys; Alonso Heredia; Brian H M Kuijpers; Floris P J T Rutjes; Floris L van Delft; Lai-Xi Wang
Enzymatic glycosylation of triazole-linked GlcNAc/Glc-peptides: synthesis, stability and anti-HIV activity of triazole-linked HIV-1 gp41 glycopeptide C34 analogues.
Chembiochem : a European journal of chemical biology 2009;10(7):1234-42.
2009: Robert J Luallen; Hu Fu; Caroline Agrawal-Gamse; Innocent Mboudjeka; Wei Huang; Fang-Hua Lee; Lai-Xi Wang; Robert W Doms; Yu Geng
A yeast glycoprotein shows high-affinity binding to the broadly neutralizing human immunodeficiency virus antibody 2G12 and inhibits gp120 interactions with 2G12 and DC-SIGN.
Journal of virology 2009;83(10):4861-70.
2009: Siaw-Lin Chan; Caroline J Voskens; Wei Lin; Daniel G Schindler; Agnes M Azimzadeh; Lai-Xi Wang; Rodney J Taylor; Scott E Strome; Dan H Schulze
Epitope mapping of a chimeric CD137 mAb: a necessary step for assessing the biologic relevance of non-human primate models.
Journal of molecular recognition : JMR 2009;22(3):242-9.
2009: Hirofumi Ochiai; Wei Huang; Lai-Xi Wang
Endo-beta-N-acetylglucosaminidase-catalyzed polymerization of beta-Glcp-(1-->4)-GlcpNAc oxazoline: a revisit to enzymatic transglycosylation.
Carbohydrate research 2009;344(5):592-8.
2009: Thomas E Newsom-Davis; Denong Wang; Lawrence Steinman; Paul F-T Chen; Lai-Xi Wang; A Katharina Simon; Gavin R Screaton
Enhanced immune recognition of cryptic glycan markers in human tumors.
Cancer research 2009;69(5):2018-25.
2009: Wei Huang; Cishan Li; Bing Li; Midori Umekawa; Kenji Yamamoto; Xinyu Zhang; Lai-Xi Wang
Glycosynthases enable a highly efficient chemoenzymatic synthesis of N-glycoproteins carrying intact natural N-glycans.
Journal of the American Chemical Society 2009;131(6):2214-23.
2009: Jie Yin; Lei Li; Neil Shaw; Yang Li; Jing Katherine Song; Wenpeng Zhang; Chengfeng Xia; Rongguang Zhang; Andrzej Joachimiak; Hou-Cheng Zhang; Lai-Xi Wang; Zhi-Jie Liu; Peng Wang
Structural basis and catalytic mechanism for the dual functional endo-beta-N-acetylglucosaminidase A.
PloS one 2009;4(3):e4658.
2008: Wei Huang; Hirofumi Ochiai; Xinyu Zhang; Lai-Xi Wang
Introducing N-glycans into natural products through a chemoenzymatic approach.
Carbohydrate research 2008;343(17):2903-13.
2008: Hirofumi Ochiai; Wei Huang; Lai-Xi Wang
Expeditious chemoenzymatic synthesis of homogeneous N-glycoproteins carrying defined oligosaccharide ligands.
Journal of the American Chemical Society 2008;130(41):13790-803.
2008: Yadong Wei; Cishan Li; Wei Huang; Bing Li; Scott E Strome; Lai-Xi Wang
Glycoengineering of human IgG1-Fc through combined yeast expression and in vitro chemoenzymatic glycosylation.
Biochemistry 2008;47(39):10294-304.
2008: Cishan Li; Wei Huang; Lai-Xi Wang
Chemoenzymatic synthesis of N-linked neoglycoproteins through a chitinase-catalyzed transglycosylation.
Bioorganic & medicinal chemistry 2008;16(18):8366-72.
2008: Wei Lin; Caroline J Voskens; Xiaoyu Zhang; Daniel G Schindler; Aaron Wood; Erin Burch; Yadong Wei; Lieping Chen; Guoliang Tian; Koji Tamada; Lai-Xi Wang; Dan H Schulze; Dean L Mann; Scott E Strome
Fc-dependent expression of CD137 on human NK cells: insights into "agonistic" effects of anti-CD137 monoclonal antibodies.
Blood 2008;112(3):699-707.
2008: Lai-Xi Wang
Chemoenzymatic synthesis of glycopeptides and glycoproteins through endoglycosidase-catalyzed transglycosylation.
Carbohydrate research 2008;343(10-11):1509-22.
2008: Bing Li; Kaoru Takegawa; Tadashi Suzuki; Kenji Yamamoto; Lai-Xi Wang
Synthesis and inhibitory activity of oligosaccharide thiazolines as a class of mechanism-based inhibitors for endo-beta-N-acetylglucosaminidases.
Bioorganic & medicinal chemistry 2008;16(8):4670-5.
2008: Midori Umekawa; Wei Huang; Bing Li; Kiyotaka Fujita; Hisashi Ashida; Lai-Xi Wang; Kenji Yamamoto
Mutants of Mucor hiemalis endo-beta-N-acetylglucosaminidase show enhanced transglycosylation and glycosynthase-like activities.
The Journal of biological chemistry 2008;283(8):4469-79.
2007: Xibing Li; Lai-Xi Wang; xuesong wang; Saul Roseman
The chitin catabolic cascade in the marine bacterium Vibrio cholerae: characterization of a unique chitin oligosaccharide deacetylase.
Glycobiology 2007;17(12):1377-87.
2007: Hengguang Li; Yongjun Guan; Agnieszka Szczepanska; Antonio J Moreno-Vargas; Ana T Carmona; Inmaculada Robina; George K Lewis; Lai-Xi Wang
Synthesis and anti-HIV activity of trivalent CD4-mimetic miniproteins.
Bioorganic & medicinal chemistry 2007;15(12):4220-8.
2007: Jingsong Wang; Hengguang Li; Guozhang Zou; Lai-Xi Wang
Novel template-assembled oligosaccharide clusters as epitope mimics for HIV-neutralizing antibody 2G12. Design, synthesis, and antibody binding study.
Organic & biomolecular chemistry 2007;5(10):1529-40.
2006: Luigi Buonaguro; Maria Lina Tornesello; Maria Tagliamonte; Robert C Gallo; Lai-Xi Wang; Roberta Kamin-Lewis; Sayed F Abdelwahab; George K Lewis; Franco M Buonaguro
Baculovirus-derived human immunodeficiency virus type 1 virus-like particles activate dendritic cells and induce ex vivo T-cell responses.
Journal of virology 2006;80(18):9134-43.
2006: Bing Li; Haijing Song; Steven Hauser; Lai-Xi Wang
A highly efficient chemoenzymatic approach toward glycoprotein synthesis.
Organic letters 2006;8(14):3081-4.
2006: Ying Zeng; Jingsong Wang; Bing Li; Steven Hauser; Hengguang Li; Lai-Xi Wang
Glycopeptide synthesis through endo-glycosidase-catalyzed oligosaccharide transfer of sugar oxazolines: probing substrate structural requirement.
Chemistry (Weinheim an der Bergstrasse, Germany) 2006;12(12):3355-64.
2006: Lai-Xi Wang
Toward oligosaccharide- and glycopeptide-based HIV vaccines.
Current opinion in drug discovery & development 2006;9(2):194-206.
2006: Jiahong Ni; Haijing Song; Yadong Wang; Nicholas M Stamatos; Lai-Xi Wang
Toward a carbohydrate-based HIV-1 vaccine: synthesis and immunological studies of oligomannose-containing glycoconjugates.
Bioconjugate chemistry 2006;17(2):493-500.
2005: Hengguang Li; Bing Li; Haijing Song; Leonid Breydo; Ilia Baskakov; Lai-Xi Wang
Chemoenzymatic synthesis of HIV-1 V3 glycopeptides carrying two N-glycans and effects of glycosylation on the peptide domain.
The Journal of organic chemistry 2005;70(24):9990-6.
2005: Bing Li; Ying Zeng; Steven Hauser; Haijing Song; Lai-Xi Wang
Highly efficient endoglycosidase-catalyzed synthesis of glycopeptides using oligosaccharide oxazolines as donor substrates.
Journal of the American Chemical Society 2005;127(27):9692-3.
2005: Lai-Xi Wang; Haijing Song; Shuwen Liu; Hong Lu; Shibo Jiang; Jiahong Ni; Hengguang Li
Chemoenzymatic synthesis of HIV-1 gp41 glycopeptides: effects of glycosylation on the anti-HIV activity and alpha-helix bundle-forming ability of peptide C34.
Chembiochem : a European journal of chemical biology 2005;6(6):1068-74.
2005: Jingsong Wang; Nhut Le; Alonso Heredia; Haijing Song; Robert R Redfield; Lai-Xi Wang
Modification and structure-activity relationship of a small molecule HIV-1 inhibitor targeting the viral envelope glycoprotein gp120.
Organic & biomolecular chemistry 2005;3(9):1781-6.
2005: Nicholas M Stamatos; Feng Liang; Xinli Nan; Karine Landry; Alan S Cross; Lai-Xi Wang; Alexey V Pshezhetsky
Differential expression of endogenous sialidases of human monocytes during cellular differentiation into macrophages.
The FEBS journal 2005;272(10):2545-56.
2005: Steven Hauser; Haijing Song; Hengguang Li; Lai-Xi Wang
A novel fluorescence-based assay for the transglycosylation activity of endo-beta-N-acetylglucosaminidases.
Biochemical and biophysical research communications 2005;328(2):580-5.
2005: Hengguang Li; Suddham Singh; Ying Zeng; Haijing Song; Lai-Xi Wang
Chemoenzymatic synthesis of CD52 glycoproteins carrying native N-glycans.
Bioorganic & medicinal chemistry letters 2005;15(4):895-8.
2004: Lai-Xi Wang; Alonso Heredia; Haijing Song; Zhaojun Zhang; Biao Yu; Charles Davis; Robert R Redfield
Resveratrol glucuronides as the metabolites of resveratrol in humans: characterization, synthesis, and anti-HIV activity.
Journal of pharmaceutical sciences 2004;93(10):2448-57.
2004: Hengguang Li; Haijing Song; Alonso Heredia; Nhut Le; Robert R Redfield; George K Lewis; Lai-Xi Wang
Synthetic bivalent CD4-mimetic miniproteins show enhanced anti-HIV activity over the monovalent miniprotein.
Bioconjugate chemistry 2004;15(4):783-9.
2004: Jiahong Ni; Robert Powell; Ilia Baskakov; Anthony DeVico; George K Lewis; Lai-Xi Wang
Synthesis, conformation, and immunogenicity of monosaccharide-centered multivalent HIV-1 gp41 peptides containing the sequence of DP178.
Bioorganic & medicinal chemistry 2004;12(12):3141-8.
2004: Kannan P Naicker; Hengguang Li; Alonso Heredia; Haijing Song; Lai-Xi Wang
Design and synthesis of alpha Gal-conjugated peptide T20 as novel antiviral agent for HIV-immunotargeting.
Organic & biomolecular chemistry 2004;2(5):660-4.
2004: Kannan P Naicker; Shibo Jiang; Hong Lu; Jiahong Ni; Louise Boyer-Chatenet; Lai-Xi Wang; Asim K Debnath
Synthesis and anti-HIV-1 activity of 4-[4-(4,6-bisphenylamino-triazin-2-ylamino)-5-methoxy-2-methylphenylazo]-5-hydroxynaphthalene-2,7-disulfonic acid and its derivatives.
Bioorganic & medicinal chemistry 2004;12(5):1215-20.
2004: Hengguang Li; Lai-Xi Wang
Design and synthesis of a template-assembled oligomannose cluster as an epitope mimic for human HIV-neutralizing antibody 2G12.
Organic & biomolecular chemistry 2004;2(4):483-8.
2004: Darren Locke; Carville G. III Bevans; Lai-Xi Wang; Ye Zhang; Andrew L Harris; Yuan C Lee
Neutral, acidic, and basic derivatives of anthranilamide that confer different formal charge to reducing oligosaccharides.
Carbohydrate research 2004;339(2):221-31.
2004: Lai-Xi Wang; Jiahong Ni; Suddham Singh; Hengguang Li
Binding of high-mannose-type oligosaccharides and synthetic oligomannose clusters to human antibody 2G12: implications for HIV-1 vaccine design.
Chemistry & biology 2004;11(1):127-34.
2003: Hengguang Li; Lai-Xi Wang
Cholic acid as template for multivalent peptide assembly.
Organic & biomolecular chemistry 2003;1(20):3507-13.
2003: B Ewa Snaar-Jagalska; S F Gabby Krens; Inmaculada Robina; Lai-Xi Wang; Herman P Spaink
Specific activation of ERK pathways by chitin oligosaccharides in embryonic zebrafish cell lines.
Glycobiology 2003;13(10):725-32.
2003: Darren Locke; Lai-Xi Wang; Carville G. III Bevans; Yuan C Lee; Andrew L Harris
Open pore block of connexin26 and connexin32 hemichannels by neutral, acidic and basic glycoconjugates.
Cell communication & adhesion 2003;10(4-6):239-44.
2003: Suddham Singh; Jiahong Ni; Lai-Xi Wang
Chemoenzymatic synthesis of high-mannose type HIV-1 gp120 glycopeptides.
Bioorganic & medicinal chemistry letters 2003;13(3):327-30.
2003: Alan S Cross; Serhan Sakarya; Salahaldin Rifat; Thomas K Held; Beth-Ellen Drysdale; Philippe A Grange; Frederick J Cassels; Lai-Xi Wang; Nicholas M Stamatos; Ann Farese; Daniel Casey; Jan Powell; Apurba K Bhattacharjee; Michael E Kleinberg; Simeon E Goldblum
Recruitment of murine neutrophils in vivo through endogenous sialidase activity.
The Journal of biological chemistry 2003;278(6):4112-20.
2003: Lai-Xi Wang; Jiahong Ni; Suddham Singh
Carbohydrate-centered maleimide cluster as a new type of templates for multivalent peptide assembling. synthesis of multivalent HIV-1 gp41 peptides.
Bioorganic & medicinal chemistry 2003;11(1):159-66.
2003: Lai-Xi Wang
Bioorganic approaches towards HIV vaccine design.
Current pharmaceutical design 2003;9(22):1771-87.
2003: Jiahong Ni; Suddham Singh; Lai-Xi Wang
Synthesis of maleimide-activated carbohydrates as chemoselective tags for site-specific glycosylation of peptides and proteins.
Bioconjugate chemistry 2003;14(1):232-8.
2002: Jae Kweon Park; Lai-Xi Wang; Himatkumar V Patel; Saul Roseman
Molecular cloning and characterization of a unique beta-glucosidase from Vibrio cholerae.
The Journal of biological chemistry 2002;277(33):29555-60.
2002: Audrey M Southwick; Lai-Xi Wang; Sharon R Long; Yuan C Lee
Activity of Sinorhizobium meliloti NodAB and NodH enzymes on thiochitooligosaccharides.
Journal of bacteriology 2002;184(14):4039-43.
2002: Jae Kweon Park; Lai-Xi Wang; Saul Roseman
Isolation of a glucosamine-specific kinase, a unique enzyme of Vibrio cholerae.
The Journal of biological chemistry 2002;277(18):15573-8.
2002: Jiahong Ni; Suddham Singh; Lai-Xi Wang
Improved preparation of perallylated cyclodextrins: facile synthesis of cyclodextrin-based polycationic and polyanionic compounds.
Carbohydrate research 2002;337(3):217-20.
2001: Lai-Xi Wang; Luis G Melean; Peter H Seeberger; Graham C Walker
Biotin labeling of the symbiotically important succinoglycan oligosaccharides of Rhizobium meliloti for identification of putative plant receptors.
Carbohydrate research 2001;333(1):73-8.
2000: M C Kasuya; Lai-Xi Wang; Y C Lee; M Mitsuki; H Nakajima; Y Miura; T Sato; K Hatanaka; S Yamagata; T Yamagata
Azido glycoside primer: a versatile building block for the biocombinatorial synthesis of glycosphingolipid analogues.
Carbohydrate research 2000;329(4):755-63.
2000: NO Keyhani; Lai-Xi Wang; Yuan C Lee; Saul Roseman
The chitin disaccharide, N,N'-diacetylchitobiose, is catabolized by Escherichia coli and is transported/phosphorylated by the phosphoenolpyruvate:glycose phosphotransferase system.
The Journal of biological chemistry 2000;275(42):33084-90.
1999: Lai-Xi Wang; Y Wang; Brett J. Pellock; Graham C Walker
Structural characterization of the symbiotically important low-molecular-weight succinoglycan of Sinorhizobium meliloti.
Journal of bacteriology 1999;181(21):6788-96.
1998: J E González; Carlos E Semino; Lai-Xi Wang; L E Castellano-Torres; Graham C Walker
Biosynthetic control of molecular weight in the polymerization of the octasaccharide subunits of succinoglycan, a symbiotically important exopolysaccharide of Rhizobium meliloti.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(23):13477-82.
1998: J Kiang; Lai-Xi Wang; M Tang; S C Szu; Yuan C Lee
Simultaneous determination of glucosamine and glucosamine 4-phosphate in Lipid A with high-performance anion-exchange chromatography (HPAEC).
Carbohydrate research 1998;312(1-2):73-6.
1998: Lai-Xi Wang; Nadejda Pavlova; M Yang; S C Li; Y T Li; Yuan C Lee
Synthesis of aryl 3'-sulfo-beta-lactosides as fluorogenic and chromogenic substrates for ceramide glycanases.
Carbohydrate research 1998;306(3):341-8.
1997: Yu-Teh Li; Lai-Xi Wang; Nadejda Pavlova; Su-Chen Li; Y C Lee
alpha-KDOase activity in oyster and synthesis of alpha- and beta-4-methylumbelliferyl ketosides of 3-deoxy-D-manno-octulosonic acid.
The Journal of biological chemistry 1997;272(42):26419-24.
1997: Lai-Xi Wang; NO Keyhani; Saul Roseman; Yuan C Lee
4-Methylumbelliferyl glycosides of N-acetyl 4-thiochito-oligosaccharides as fluorogenic substrates for chitodextrinase from Vibrio furnissii.
Glycobiology 1997;7(6):855-60.
1997: J Kiang; S C Szu; Lai-Xi Wang; M Tang; Yuan C Lee
Determination of 2-keto-3-deoxyoctulosonic acid (KDO) with high-performance anion-exchange chromatography (HPAEC): survey of stability of KDO and optimal hydrolytic conditions.
Analytical biochemistry 1997;245(1):97-101.
1996: NO Keyhani; Lai-Xi Wang; Yuan C Lee; Saul Roseman
The chitin catabolic cascade in the marine bacterium Vibrio furnissii. Characterization of an N,N'-diacetyl-chitobiose transport system.
The Journal of biological chemistry 1996;271(52):33409-13.
1996: Lai-Xi Wang; Nadejda Pavlova; Su-Chen Li; Yu-Teh Li; Yuan C Lee
A fluorometric assay of ceramide glycanase with 4-methylumbelliferyl beta-D-lactoside derivatives.
Glycoconjugate journal 1996;13(3):359-65.
1995: Lai-Xi Wang; Nobuo Sakairi; H Kuzuhara
Synthesis of 1D-(1,3,5/2,4)-4-acetamido-5-amino-1,2,3-cyclohexanetriol and its incorporation into a pseudo-disaccharide.
Carbohydrate research 1995;275(1):33-47.
1991: Lai-Xi Wang; Nobuo Sakairi; H Kuzuhara
Peracetylated laminaribiose: preparation by specific degradation of curdlan and its chemical conversion into N-acetylhyalobiuronic acid.
Carbohydrate research 1991;219():133-48.