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Minghui Wang

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James J Cody; Jason W Ashley; Xu Feng; Gray R Lyons; Sreelatha Meleth; Angel A Rivera; Gene P Siegal; Minghui Wang; Sherry W Yang; Joanne T Douglas
Expression of osteoprotegerin from a replicating adenovirus inhibits the progression of prostate cancer bone metastases in a murine model.
Hideyo Ugai; Minghui Wang; George C Dobbins; Long P Le; David A Matthews; David T Curiel
Adenoviral protein V promotes a process of viral assembly through nucleophosmin 1.
Sherry W Yang; James J Cody; Angel A Rivera; Reinhard Waehler; Minghui Wang; Kristopher J Kimball; Ronald A Alvarez; Gene P Siegal; Joanne T Douglas; Selvarangan Ponnazhagan
Conditionally replicating adenovirus expressing TIMP2 for ovarian cancer therapy.

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All Publications

2013: James J Cody; Jason W Ashley; Xu Feng; Gray R Lyons; Sreelatha Meleth; Angel A Rivera; Gene P Siegal; Minghui Wang; Sherry W Yang; Joanne T Douglas
Expression of osteoprotegerin from a replicating adenovirus inhibits the progression of prostate cancer bone metastases in a murine model.
Laboratory investigation; a journal of technical methods and pathology 2013;93(3):268-78.
2012: Hideyo Ugai; Minghui Wang; George C Dobbins; Long P Le; David A Matthews; David T Curiel
Adenoviral protein V promotes a process of viral assembly through nucleophosmin 1.
Virology 2012;432(2):283-95.
2011: Sherry W Yang; James J Cody; Angel A Rivera; Reinhard Waehler; Minghui Wang; Kristopher J Kimball; Ronald A Alvarez; Gene P Siegal; Joanne T Douglas; Selvarangan Ponnazhagan
Conditionally replicating adenovirus expressing TIMP2 for ovarian cancer therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(3):538-49.
2010: J J Cody; Angel A Rivera; G R Lyons; S W Yang; Minghui Wang; D B Sarver; D Wang; K S Selander; H-C Kuo; Sreelatha Meleth; Xu Feng; G P Siegal; G P Siegall; Joanne T Douglas
Arming a replicating adenovirus with osteoprotegerin reduces the tumor burden in a murine model of osteolytic bone metastases of breast cancer.
Cancer gene therapy 2010;17(12):893-905.
2010: Miho Murakami; Hideyo Ugai; Minghui Wang; Natalya Belousova; Paul Dent; Paul B Fisher; Joel N Glasgow; Maaike Everts; David T Curiel
An adenoviral vector expressing human adenovirus 5 and 3 fiber proteins for targeting heterogeneous cell populations.
Virology 2010;407(2):196-205.
2010: A A V Paupoo; Zeng B Zhu; Minghui Wang; Daniel T Rein; A Starzinski-Powitz; David T Curiel
A conditionally replicative adenovirus, CRAd-S-pK7, can target endometriosis with a cell-killing effect.
Human reproduction (Oxford, England) 2010;25(8):2068-83.
2010: Anton V Borovjagin; Lacey R McNally; Minghui Wang; David T Curiel; Mary J MacDougall; Kurt R Zinn
Noninvasive monitoring of mRFP1- and mCherry-labeled oncolytic adenoviruses in an orthotopic breast cancer model by spectral imaging.
Molecular imaging 2010;9(2):59-75.
2010: Hideyo Ugai; Minghui Wang; Long P Le; David A Matthews; Masato Yamamoto; David T Curiel
In vitro dynamic visualization analysis of fluorescently labeled minor capsid protein IX and core protein V by simultaneous detection.
Journal of molecular biology 2010;395(1):55-78.
2010: Jing Li; Aiman Fatima; Svetlana Komarova; Hideyo Ugai; Priyanka Uprety; Justin C Roth; Minghui Wang; Robert A Oster; David T Curiel; Qiana L Matthews
Evaluation of adenovirus capsid labeling versus transgene expression.
Virology journal 2010;7():21.
2009: Kellie Matthews; Patricia E Noker; Baohong Tian; Sheila D Grimes; Ronna Fulton; Karen Schweikart; Raymond Harris; Rose Aurigemma; Minghui Wang; Mack N Barnes; Gene P Siegal; Akseli Hemminki; Kurt Zinn; David T Curiel; Ronald D Alvarez
Identifying the safety profile of Ad5.SSTR/TK.RGD, a novel infectivity-enhanced bicistronic adenovirus, in anticipation of a phase I clinical trial in patients with recurrent ovarian cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(12):4131-7.
2008: Zeng B Zhu; Baogen Lu; Miey Park; Sharmila K Makhija; Thomas M Numnum; James E Kendrick; Minghui Wang; Yuko Tsuruta; Paul Fisher; Ronald D Alvarez; Fen Zhou; Gene P Siegal; Hongju Wu; David T Curiel
Development of an optimized conditionally replicative adenoviral agent for ovarian cancer.
International journal of oncology 2008;32(6):1179-88.
2008: T Michael Numnum; Sharmila K Makhija; Baogen Lu; Minghui Wang; Angel Rivera; Mariam A Stoff-Khalili; Ronald D Alvarez; Zeng B Zhu; David T Curiel
Improved anti-tumor therapy based upon infectivity-enhanced adenoviral delivery of RNA interference in ovarian carcinoma cell lines.
Gynecologic oncology 2008;108(1):34-41.
2007: Zeng B Zhu; J Michael Mathis; Sharmila K Makhija; Baogen Lu; Minghui Wang; Shaonin Ji; Angel A Rivera; Eben Rosenthal; Gene P Siegal; David T Curiel
Targeting of a conditionally replicative adenovirus agent to human squamous cell carcinomas of the head and neck.
International journal of oncology 2007;31(5):1213-22.
2007: Rodney P Rocconi; Zeng B Zhu; Mariam A Stoff-Khalili; Angel A Rivera; Baogen Lu; Minghui Wang; Ronald D Alvarez; David T Curiel; Sharmila K Makhija
Treatment of ovarian cancer with a novel dual targeted conditionally replicative adenovirus (CRAd).
Gynecologic oncology 2007;105(1):113-21.
2007: Hideyo Ugai; Anton V Borovjagin; Long P Le; Minghui Wang; David T Curiel
Thermostability/infectivity defect caused by deletion of the core protein V gene in human adenovirus type 5 is rescued by thermo-selectable mutations in the core protein X precursor.
Journal of molecular biology 2007;366(4):1142-60.
2007: Zeng B Zhu; Angel A Rivera; Sharmila K Makhija; Baogen Lu; Minghui Wang; Miiru Izumi; Robert James Cerfolio; Mariam A Stoff-Khalili; Fen Zhou; Koichi Takayama; Gene P Siegal; David T Curiel
Targeting lung cancer using an infectivity enhanced CXCR4-CRAd.
Lung cancer (Amsterdam, Netherlands) 2007;55(2):145-56.
2006: Rodney P Rocconi; Michael T Numnum; Zeng B Zhu; Baogen Lu; Minghui Wang; Angel A Rivera; Mariam A Stoff-Khalili; Ronald D Alvarez; David T Curiel; Sharmila K Makhija
Icodextrin enhances survival in an intraperitoneal ovarian cancer murine model utilizing gene therapy.
Gynecologic oncology 2006;103(3):985-9.
2006: Zeng B Zhu; Yabing Chen; Sharmila K Makhija; Baogen Lu; Minghui Wang; Angel A Rivera; Masato Yamamoto; shuyi wang; Gene P Siegal; David T Curiel; Jay M McDonald
Survivin promoter-based conditionally replicative adenoviruses target cholangiocarcinoma.
International journal of oncology 2006;29(5):1319-29.
2006: Natalya Belousova; Raymond Harris; Kurt R Zinn; Mary Ann Rhodes-Selser; Alexander Kotov; Olga Kotova; Minghui Wang; Rosemarie Aurigemma; Zeng B Zhu; David T Curiel; Ronald D Alvarez
Circumventing recombination events encountered with production of a clinical-grade adenoviral vector with a double-expression cassette.
Molecular pharmacology 2006;70(5):1488-93.
2006: Zeng B Zhu; Sharmila K Makhija; Baogen Lu; Minghui Wang; shuyi wang; Koichi Takayama; Gene P Siegal; Paul N Reynolds; David T Curiel
Targeting mesothelioma using an infectivity enhanced survivin-conditionally replicative adenoviruses.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2006;1(7):701-11.
2006: Winan J van Houdt; Yosef S Haviv; Baogen Lu; Minghui Wang; Angel A Rivera; Ilya V Ulasov; Martine L M Lamfers; Daniel T Rein; Lesniak Maciej; Gene P Siegal; Clemens M F Dirven; David T Curiel; Zeng B Zhu
The human survivin promoter: a novel transcriptional targeting strategy for treatment of glioma.
Journal of neurosurgery 2006;104(4):583-92.
2006: Long P Le; Angel A Rivera; Joel N Glasgow; Vladimir V Ternovoi; Hongju Wu; Minghui Wang; Bruce F Smith; Gene P Siegal; David T Curiel
Infectivity enhancement for adenoviral transduction of canine osteosarcoma cells.
Gene therapy 2006;13(5):389-99.
2005: Miiru Izumi; Yosuke Kawakami; Joel N Glasgow; Natalya Belousova; Maaike Everts; SangAe Kim-Park; Seiji Yamamoto; Minghui Wang; Long P Le; Paul N Reynolds; David T Curiel
In vivo analysis of a genetically modified adenoviral vector targeted to human CD40 using a novel transient transgenic model.
The journal of gene medicine 2005;7(12):1517-25.
2005: Michael J Passineau; Gene P Siegal; Maaike Everts; Alexander Pereboev; Darshana Jhala; Minghui Wang; Zeng B Zhu; Sangae Kim Park; David T Curiel; Gina M Nelson
The natural history of a novel, systemic, disseminated model of syngeneic mouse B-cell lymphoma.
Leukemia & lymphoma 2005;46(11):1627-1638.
2005: Mariam A Stoff-Khalili; Alexander Stoff; Angel A Rivera; J Michael Mathis; Maaike Everts; Minghui Wang; Yosuke Kawakami; Reinhard Waehler; Quiana L Mathews; Masato Yamamoto; Rodney P Rocconi; Gene P Siegal; Dirk F Richter; Peter Dall; Zeng B Zhu; David T Curiel
Gene transfer to carcinoma of the breast with fiber-modified adenoviral vectors in a tissue slice model system.
Cancer biology & therapy 2005;4(11):1203-10.
2005: Zeng B Zhu; Sharmila K Makhija; Baogen Lu; Minghui Wang; Angel A Rivera; SangAe Kim-Park; Ilya V Ulasov; Fen Zhou; Ronald D Alvarez; Gene P Siegal; David T Curiel
Incorporating the survivin promoter in an infectivity enhanced CRAd-analysis of oncolysis and anti-tumor effects in vitro and in vivo.
International journal of oncology 2005;27(1):237-46.
2005: Daniel T Rein; Martina Breidenbach; Tyler O Kirby; Tie Han; Gene P Siegal; Gerd J Bauerschmitz; Minghui Wang; Dirk M Nettelbeck; Yuko Tsuruta; Masato Yamamoto; Peter Dall; Akseli Hemminki; David T Curiel
A fiber-modified, secretory leukoprotease inhibitor promoter-based conditionally replicating adenovirus for treatment of ovarian cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(3):1327-35.
2005: Baogen Lu; Sharmila K Makhija; Dirk M Nettelbeck; Angel A Rivera; Minghui Wang; Svetlana Komarova; Fen Zhou; Masato Yamamoto; Hidde J Haisma; Ronald D Alvarez; David T Curiel; Zeng B Zhu
Evaluation of tumor-specific promoter activities in melanoma.
Gene therapy 2005;12(4):330-8.
2005: Minghui Wang; Akseli Hemminki; Gene P Siegal; Mack N Barnes; Igor Dmitriev; Victor Krasnykh; Bin Liu; David T Curiel; Ronald D Alvarez
Adenoviruses with an RGD-4C modification of the fiber knob elicit a neutralizing antibody response but continue to allow enhanced gene delivery.
Gynecologic oncology 2005;96(2):341-8.
2005: Mariam A Stoff-Khalili; Alexander Stoff; Angel A Rivera; nirupama banerjee; Maaike Everts; Scott Young; Gene P Siegal; Dirk F Richter; Minghui Wang; Peter Dall; J Michael Mathis; Zeng B Zhu; David T Curiel
Preclinical evaluation of transcriptional targeting strategies for carcinoma of the breast in a tissue slice model system.
Breast cancer research : BCR 2005;7(6):R1141-52.
2005: Martina Breidenbach; Daniel T Rein; Maaike Everts; Joel N Glasgow; Minghui Wang; Michael J Passineau; Ronald D Alvarez; Nikolay Korokhov; David T Curiel
Mesothelin-mediated targeting of adenoviral vectors for ovarian cancer gene therapy.
Gene therapy 2005;12(2):187-93.
2004: Tyler O Kirby; Angel Rivera; Daniel T Rein; Minghui Wang; Ilya V Ulasov; Martina Breidenbach; Manjula Kataram; Juan L Contreras; Carlos Krumdieck; Masato Yamamoto; Marianne G Rots; Hidde J Haisma; Ronald D Alvarez; Parameshwar J Mahasreshti; David T Curiel
A novel ex vivo model system for evaluation of conditionally replicative adenoviruses therapeutic efficacy and toxicity.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(24):8697-703.
2004: Angel A Rivera; Julia Davydova; S Schierer; Minghui Wang; Victor Krasnykh; Masato Yamamoto; David T Curiel; Dirk M Nettelbeck
Combining high selectivity of replication with fiber chimerism for effective adenoviral oncolysis of CAR-negative melanoma cells.
Gene therapy 2004;11(23):1694-702.
2004: John T Lam; Anna Kanerva; Gerd J Bauerschmitz; Koichi Takayama; Kaori Suzuki; Masato Yamamoto; Snehal M Bhoola; Bin Liu; Minghui Wang; Mack N Barnes; Ronald D Alvarez; Gene P Siegal; David T Curiel; Akseli Hemminki
Inter-patient variation in efficacy of five oncolytic adenovirus candidates for ovarian cancer therapy.
The journal of gene medicine 2004;6(12):1333-42.
2004: Daniel T Rein; Martina Breidenbach; Dirk M Nettelbeck; Yosuke Kawakami; Gene P Siegal; Warner K Huh; Minghui Wang; Akseli Hemminki; Gerd J Bauerschmitz; Masato Yamamoto; Yasuo Adachi; Koichi Takayama; Peter Dall; David T Curiel
Evaluation of tissue-specific promoters in carcinomas of the cervix uteri.
The journal of gene medicine 2004;6(11):1281-9.
2004: Daniel T Rein; Martina Breidenbach; Hongju Wu; Tie Han; Yosef S Haviv; Minghui Wang; Tyler O Kirby; Yosuke Kawakami; Peter Dall; Ronald D Alvarez; David T Curiel
Gene transfer to cervical cancer with fiber-modified adenoviruses.
International journal of cancer. Journal international du cancer 2004;111(5):698-704.
2004: Gerd J Bauerschmitz; Anna Kanerva; Minghui Wang; Isabell Herrmann; Denise R Shaw; Theresa V Strong; Renee A Desmond; Daniel T Rein; Peter Dall; David T Curiel; Akseli Hemminki
Evaluation of a selectively oncolytic adenovirus for local and systemic treatment of cervical cancer.
International journal of cancer. Journal international du cancer 2004;111(2):303-9.
2004: Zeng B Zhu; Sharmila K Makhija; Baogen Lu; Minghui Wang; Angel A Rivera; Meredith Preuss; Fen Zhou; Gene P Siegal; Ronald D Alvarez; David T Curiel
Transport across a polarized monolayer of Caco-2 cells by transferrin receptor-mediated adenovirus transcytosis.
Virology 2004;325(1):116-28.
2004: Julia Davydova; Long P Le; Tatyana Gavrikova; Minghui Wang; Victor Krasnykh; Masato Yamamoto
Infectivity-enhanced cyclooxygenase-2-based conditionally replicative adenoviruses for esophageal adenocarcinoma treatment.
Cancer research 2004;64(12):4319-27.
2004: Martina Breidenbach; Daniel T Rein; Minghui Wang; Dirk M Nettelbeck; Akseli Hemminki; Ilya V Ulasov; Angel R Rivera; Maaike Everts; Ronald D Alvarez; Joanne T Douglas; David T Curiel
Genetic replacement of the adenovirus shaft fiber reduces liver tropism in ovarian cancer gene therapy.
Human gene therapy 2004;15(5):509-18.
2004: Meredith A Preuss; John T Lam; Minghui Wang; Charles A Leath; Manjula Kataram; Parameshwar J Mahasreshti; Ronald D Alvarez; David T Curiel
Transcriptional blocks limit adenoviral replication in primary ovarian tumor.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(9):3189-94.
2004: nirupama banerjee; Angel A Rivera; Minghui Wang; Louise T Chow; Thomas R Broker; David T Curiel; Dirk M Nettelbeck
Analyses of melanoma-targeted oncolytic adenoviruses with tyrosinase enhancer/promoter-driven E1A, E4, or both in submerged cells and organotypic cultures.
Molecular cancer therapeutics 2004;3(4):437-49.
2004: Zeng B Zhu; Sharmila K Makhija; Baogen Lu; Minghui Wang; Lyudmila N Kaliberova; Bin Liu; Angel A Rivera; Dirk M Nettelbeck; Parameshwar J Mahasreshti; Charles A Leath; Masato Yamamoto; M Yamaoto; Ronald D Alvarez; David T Curiel
Transcriptional targeting of adenoviral vector through the CXCR4 tumor-specific promoter.
Gene therapy 2004;11(7):645-8.
2004: Zeng B Zhu; Sharmila K Makhija; Baogen Lu; Minghui Wang; Lyudmila N Kaliberova; Bin Liu; Angel A Rivera; Dirk M Nettelbeck; Parameshwar J Mahasreshti; Charles A Leath; Shannon Barker; Masato Yamaoto; Fengzhi Li; Ronald D Alvarez; David T Curiel
Transcriptional targeting of tumors with a novel tumor-specific survivin promoter.
Cancer gene therapy 2004;11(4):256-62.
2004: Angel A Rivera; Minghui Wang; Kaori Suzuki; taco uil; Victor Krasnykh; David T Curiel; Dirk M Nettelbeck
Mode of transgene expression after fusion to early or late viral genes of a conditionally replicating adenovirus via an optimized internal ribosome entry site in vitro and in vivo.
Virology 2004;320(1):121-34.
2003: Yosef S Haviv; Koichi Takayama; Peter Nagi; Albert Tousson; William Cook; Minghui Wang; John T Lam; Seiji Naito; Xiaosheng Lei; Delicia E Carey; David T Curiel
Modulation of renal glomerular disease using remote delivery of adenoviral-encoded solubletype II TGF-beta receptor fusion molecule.
The journal of gene medicine 2003;5(10):839-51.
2003: Masato Yamamoto; Julia Davydova; Minghui Wang; Gene P Siegal; Victor Krasnykh; Selwyn M Vickers; David T Curiel
Infectivity enhanced, cyclooxygenase-2 promoter-based conditionally replicative adenovirus for pancreatic cancer.
Gastroenterology 2003;125(4):1203-18.
2003: Anna Kanerva; Kurt R Zinn; Tandra R Chaudhuri; John T Lam; Kaori Suzuki; taco uil; Tanja Hakkarainen; Gerd J Bauerschmitz; Minghui Wang; Bin Liu; Zhihong Cao; Ronald D Alvarez; David T Curiel; Akseli Hemminki
Enhanced therapeutic efficacy for ovarian cancer with a serotype 3 receptor-targeted oncolytic adenovirus.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;8(3):449-58.
2003: Akseli Hemminki; Minghui Wang; Tanja Hakkarainen; Renee A Desmond; Jarmo Wahlfors; David T Curiel
Production of an EGFR targeting molecule from a conditionally replicating adenovirus impairs its oncolytic potential.
Cancer gene therapy 2003;10(8):583-8.
2003: John T Lam; Gerd J Bauerschmitz; Anna Kanerva; Shannon D Barker; J Michael Straughn; Minghui Wang; Mack N Barnes; Jerry L Blackwell; Gene P Siegal; Ronald D Alvarez; David T Curiel; Akseli Hemminki
Replication of an integrin targeted conditionally replicating adenovirus on primary ovarian cancer spheroids.
Cancer gene therapy 2003;10(5):377-87.
2003: Akseli Hemminki; Anna Kanerva; Bin Liu; Minghui Wang; Ronald D Alvarez; Gene P Siegal; David T Curiel
Modulation of coxsackie-adenovirus receptor expression for increased adenoviral transgene expression.
Cancer research 2003;63(4):847-53.
2003: Akseli Hemminki; Anna Kanerva; Eric J Kremer; Gerd J Bauerschmitz; Bruce F Smith; Bin Liu; Minghui Wang; Renee A Desmond; Anne Keriel; Brian G Barnett; Henry J Baker; Gene P Siegal; David T Curiel
A canine conditionally replicating adenovirus for evaluating oncolytic virotherapy in a syngeneic animal model.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;7(2):163-73.
2002: Hongju Wu; Igor Dmitriev; Elena Kashentseva; Toshiro Seki; Minghui Wang; David T Curiel
Construction and characterization of adenovirus serotype 5 packaged by serotype 3 hexon.
Journal of virology 2002;76(24):12775-82.
2002: Akseli Hemminki; Minghui Wang; Renee A Desmond; Theresa V Strong; Ronald D Alvarez; David T Curiel
Serum and ascites neutralizing antibodies in ovarian cancer patients treated with intraperitoneal adenoviral gene therapy.
Human gene therapy 2002;13(12):1505-14.
2002: Yosef S Haviv; Jerry L Blackwell; Anna Kanerva; Peter Nagi; Victor Krasnykh; Igor Dmitriev; Minghui Wang; Seiji Naito; Xiaosheng Lei; Akseli Hemminki; Delicia Carey; David T Curiel
Adenoviral gene therapy for renal cancer requires retargeting to alternative cellular receptors.
Cancer research 2002;62(15):4273-81.
2002: Toshiro Seki; Igor Dmitriev; Kaori Suzuki; Elena Kashentseva; Koichi Takayama; Marianne G Rots; taco uil; Hongju Wu; Minghui Wang; David T Curiel
Fiber shaft extension in combination with HI loop ligands augments infectivity for CAR-negative tumor targets but does not enhance hepatotropism in vivo.
Gene therapy 2002;9(16):1101-8.
2002: Anna Kanerva; Minghui Wang; Gerd J Bauerschmitz; John T Lam; Renee A Desmond; Snehal M Bhoola; Mack N Barnes; Ronald D Alvarez; Gene P Siegal; David T Curiel; Akseli Hemminki
Gene transfer to ovarian cancer versus normal tissues with fiber-modified adenoviruses.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;5(6):695-704.
2002: Yosef S Haviv; Koichi Takayama; Joel N Glasgow; Jerry L Blackwell; Minghui Wang; Xiaosheng Lei; David T Curiel
A model system for the design of armed replicating adenoviruses using p53 as a candidate transgene.
Molecular cancer therapeutics 2002;1(5):321-8.
2002: Waleed O Arafat; Jesús Gómez-Navarro; Donald J Buchsbaum; Jialing Xiang; Minghui Wang; Enrique Casado; Shannon D Barker; Parameshwar J Mahasreshti; Hidde J Haisma; Mack N Barnes; Gene P Siegal; Ronald D Alvarez; Akseli Hemminki; Dirk M Nettelbeck; David T Curiel
Effective single chain antibody (scFv) concentrations in vivo via adenoviral vector mediated expression of secretory scFv.
Gene therapy 2002;9(4):256-62.
2001: Yosef S Haviv; Jerry L Blackwell; Hui Li; Minghui Wang; Xiaosheng Lei; David T Curiel
Heat shock and heat shock protein 70i enhance the oncolytic effect of replicative adenovirus.
Cancer research 2001;61(23):8361-5.
2001: Yasuo Adachi; Paul N Reynolds; Masato Yamamoto; Minghui Wang; Koichi Takayama; Shyuichiro Matsubara; Takashi Muramatsu; David T Curiel
A midkine promoter-based conditionally replicative adenovirus for treatment of pediatric solid tumors and bone marrow tumor purging.
Cancer research 2001;61(21):7882-8.
2001: Akseli Hemminki; Natalya Belousova; Kurt R Zinn; Bin Liu; Minghui Wang; Tandra R Chaudhuri; Buck E Rogers; Donald J Buchsbaum; Gene P Siegal; Mack N Barnes; Jesus Gomez-Navarro; David T Curiel; Ronald D Alvarez
An adenovirus with enhanced infectivity mediates molecular chemotherapy of ovarian cancer cells and allows imaging of gene expression.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;4(3):223-31.
2000: Waleed O Arafat; Enrique Casado; Minghui Wang; Ronald D Alvarez; Gene P Siegal; Joseph C Glorioso; David T Curiel; Jesús Gómez-Navarro
Genetically modified CD34+ cells exert a cytotoxic bystander effect on human endothelial and cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(11):4442-8.
2000: Ronald D Alvarez; Jesus Gomez-Navarro; Minghui Wang; Mack N Barnes; Theresa V Strong; Ramin B Arani; Waleed O Arafat; J V Hughes; Gene P Siegal; David T Curiel
Adenoviral-mediated suicide gene therapy for ovarian cancer.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;2(5):524-30.
2000: Ronald D Alvarez; Mack N Barnes; Jesus Gomez-Navarro; Minghui Wang; Theresa V Strong; Waleed O Arafat; Ramin B Arani; Martin R Johnson; B L Roberts; Gene P Siegal; David T Curiel
A cancer gene therapy approach utilizing an anti-erbB-2 single-chain antibody-encoding adenovirus (AD21): a phase I trial.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(8):3081-7.
1999: T J Vanderkwaak; Minghui Wang; Jesús Gómez-Navarro; Claudine Rancourt; Igor Dmitriev; Victor Krasnykh; Mack Barnes; Gene P Siegal; R Alvarez; David T Curiel
An advanced generation of adenoviral vectors selectively enhances gene transfer for ovarian cancer gene therapy approaches.
Gynecologic oncology 1999;74(2):227-34.
1999: Claudine Rancourt; Alain Piché; Jesus Gomez-Navarro; Minghui Wang; Ronald D Alvarez; Gene P Siegal; Gerald M Fuller; SA Jones; David T Curiel
Interleukin-6 modulated conditionally replicative adenovirus as an antitumor/cytotoxic agent for cancer therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(1):43-50.
1998: Igor Dmitriev; Victor Krasnykh; Ryan Miller; Minghui Wang; Elena Kashentseva; Galina Mikheeva; Natalya Belousova; David T Curiel
An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism.
Journal of virology 1998;72(12):9706-13.
1998: Minghui Wang; Claudine Rancourt; Jesus Gomez-Navarro; David M Krisky; Pierfrancesco Marconi; Thomas J Oligino; Ronald D Alvarez; Gene P Siegal; Joseph C Glorioso; David T Curiel
High-efficacy thymidine kinase gene transfer to ovarian cancer cell lines mediated by herpes simplex virus type 1 vector.
Gynecologic oncology 1998;71(2):278-87.
1998: Claudine Rancourt; Buck E Rogers; Barbara A Sosnowski; Minghui Wang; Alain Piché; Glenn F Pierce; Ronald D Alvarez; Gene P Siegal; Joanne T Douglas; David T Curiel
Basic fibroblast growth factor enhancement of adenovirus-mediated delivery of the herpes simplex virus thymidine kinase gene results in augmented therapeutic benefit in a murine model of ovarian cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(10):2455-61.
1998: MW Robertson; Minghui Wang; Gene P Siegal; M Rosenfeld; R S Ashford; Ronald D Alvarez; Robert I Garver; David T Curiel
Use of a tissue-specific promoter for targeted expression of the herpes simplex virus thymidine kinase gene in cervical carcinoma cells.
Cancer gene therapy 1998;5(5):331-6.
1998: MW Robertson; Mack N Barnes; Claudine Rancourt; Minghui Wang; JE Grim; Ronald D Alvarez; Gene P Siegal; David T Curiel
Gene therapy for ovarian carcinoma.
Seminars in oncology 1998;25(3):397-406.
1998: Claudine Rancourt; MW Robertson; Minghui Wang; CK Goldman; J F Kelly; Ronald D Alvarez; Gene P Siegal; David T Curiel
Endothelial cell vehicles for delivery of cytotoxic genes as a gene therapy approach for carcinoma of the ovary.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(2):265-70.
1997: Jessy Deshane; Gene P Siegal; Minghui Wang; Marcienne Wright; R Pat Bucy; Ronald D Alvarez; David T Curiel
Transductional efficacy and safety of an intraperitoneally delivered adenovirus encoding an anti-erbB-2 intracellular single-chain antibody for ovarian cancer gene therapy.
Gynecologic oncology 1997;64(3):378-85.
1996: M E Rosenfeld; Minghui Wang; Gene P Siegal; Ronald D Alvarez; Galina Mikheeva; Victor Krasnykh; David T Curiel
Adenoviral-mediated delivery of herpes simplex virus thymidine kinase results in tumor reduction and prolonged survival in a SCID mouse model of human ovarian carcinoma.
Journal of molecular medicine (Berlin, Germany) 1996;74(8):455-62.