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Meifang Wang

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Chemicals & Drugs

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Publications

TOP 3
Siddhartha Kar; Meifang Wang; Brian I Carr
2-Methoxyestradiol inhibits hepatocellular carcinoma cell growth by inhibiting Cdc25 and inducing cell cycle arrest and apoptosis.
Siddhartha Kar; Meifang Wang; Brian I Carr
alpha-Thrombin inhibits DNA synthesis in rat hepatocytes but not in hepatoma cells by receptor activation and proteolysis.
Brian I Carr; Siddhartha Kar; Meifang Wang; Ziqiu Wang
Growth inhibitory actions of prothrombin on normal hepatocytes: influence of matrix.

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All Publications

2008: Siddhartha Kar; Meifang Wang; Brian I Carr
2-Methoxyestradiol inhibits hepatocellular carcinoma cell growth by inhibiting Cdc25 and inducing cell cycle arrest and apoptosis.
Cancer chemotherapy and pharmacology 2008;62(5):831-40.
2007: Siddhartha Kar; Meifang Wang; Brian I Carr
alpha-Thrombin inhibits DNA synthesis in rat hepatocytes but not in hepatoma cells by receptor activation and proteolysis.
Molecular and cellular biochemistry 2007;304(1-2):189-97.
2007: Brian I Carr; Siddhartha Kar; Meifang Wang; Ziqiu Wang
Growth inhibitory actions of prothrombin on normal hepatocytes: influence of matrix.
Cell biology international 2007;31(9):929-38.
2006: Siddhartha Kar; Meifang Wang; Seung Wook Ham; Brian I Carr
Fluorinated Cpd 5, a pure arylating K-vitamin derivative, inhibits human hepatoma cell growth by inhibiting Cdc25 and activating MAPK.
Biochemical pharmacology 2006;72(10):1217-27.
2006: Siddhartha Kar; Meifang Wang; Seung Wook Ham; Brian I Carr
H32, a non-quinone sulfone analog of vitamin K3, inhibits human hepatoma cell growth by inhibiting Cdc25 and activating ERK.
Cancer biology & therapy 2006;5(10):1340-7.
2006: Ziqiu Wang; Lisheng Ge; Meifang Wang; Brian I Carr
Phosphorylation regulates Myc expression via prolonged activation of the mitogen-activated protein kinase pathway.
Journal of cellular physiology 2006;208(1):133-40.
2006: Siddhartha Kar; Meifang Wang; Wei Yao; Christopher J Michejda; Brian I Carr
PM-20, a novel inhibitor of Cdc25A, induces extracellular signal-regulated kinase 1/2 phosphorylation and inhibits hepatocellular carcinoma growth in vitro and in vivo.
Molecular cancer therapeutics 2006;5(6):1511-9.
2005: Ziqiu Wang; Baochun Zhang; Meifang Wang; Brian I Carr
Cdc25A and ERK interaction: EGFR-independent ERK activation by a protein phosphatase Cdc25A inhibitor, compound 5.
Journal of cellular physiology 2005;204(2):437-44.
2005: Ziqiu Wang; Meifang Wang; Brian I Carr
Hepatocyte growth factor enhances protein phosphatase Cdc25A inhibitor compound 5-induced hepatoma cell growth inhibition via Akt-mediated MAPK pathway.
Journal of cellular physiology 2005;203(3):510-9.
2005: Vincent Peyregne; Siddhartha Kar; Seung Wook Ham; Meifang Wang; Ziqiu Wang; Brian I Carr
Novel hydroxyl naphthoquinones with potent Cdc25 antagonizing and growth inhibitory properties.
Molecular cancer therapeutics 2005;4(4):595-602.
2004: Siddhartha Kar; Meifang Wang; Kathryn S Rosi; Craig S Wilcox; Brian I Carr
Inhibition of rat liver regeneration after partial hepatectomy and induction of ERK phosphorylation by Cpd 5, a K vitamin-based anticancer compound.
Carcinogenesis 2004;25(12):2345-51.
2004: Lisheng Ge; Ziqiu Wang; Meifang Wang; Siddhartha Kar; Brian I Carr
Involvement of c-Myc in growth inhibition of Hep 3B human hepatoma cells by a vitamin K analog.
Journal of hepatology 2004;41(5):823-9.
2003: Zhenggang Ren; Siddhartha Kar; Ziqiu Wang; Meifang Wang; Joseph E Saavedra; Brian I Carr
JS-K, a novel non-ionic diazeniumdiolate derivative, inhibits Hep 3B hepatoma cell growth and induces c-Jun phosphorylation via multiple MAP kinase pathways.
Journal of cellular physiology 2003;197(3):426-34.
2003: Siddhartha Kar; Iliya Lefterov; Meifang Wang; John Lazo; Colleen N Scott; Craig S Wilcox; Brian I Carr
Binding and inhibition of Cdc25 phosphatases by vitamin K analogues.
Biochemistry 2003;42(35):10490-7.
2003: Ziqiu Wang; Baochun Zhang; Meifang Wang; Brian I Carr
Persistent ERK phosphorylation negatively regulates cAMP response element-binding protein (CREB) activity via recruitment of CREB-binding protein to pp90RSK.
The Journal of biological chemistry 2003;278(13):11138-44.
2003: Siddhartha Kar; Meifang Wang; Craig S Wilcox; Brian I Carr
Antitumor and anticarcinogenic actions of Cpd 5: a new class of protein phosphatase inhibitor.
Carcinogenesis 2003;24(3):411-6.
2003: Brian I Carr; Ziqiu Wang; Meifang Wang; Siddhartha Kar; Craig S Wilcox; Kathryn S Rosi; Eileen C Southwick; John Lazo
A Cdc25A antagonizing K vitamin inhibits hepatocyte DNA synthesis in vitro and in vivo.
Journal of molecular biology 2003;326(3):721-35.
2002: Takahito Adachi; Siddhartha Kar; Meifang Wang; Brian I Carr
Transient and sustained ERK phosphorylation and nuclear translocation in growth control.
Journal of cellular physiology 2002;192(2):151-9.
2002: Ziqiu Wang; Meifang Wang; John Lazo; Brian I Carr
Identification of epidermal growth factor receptor as a target of Cdc25A protein phosphatase.
The Journal of biological chemistry 2002;277(22):19470-5.
2002: Ziqiu Wang; Yuji Nishikawa; Meifang Wang; Brian I Carr
Induction of apoptosis via mitogen-activated protein kinase pathway by a K vitamin analog in rat hepatocytes.
Journal of hepatology 2002;36(1):85-92.
2001: Ziqiu Wang; Eileen C Southwick; Meifang Wang; Siddhartha Kar; Kathryn S Rosi; Craig S Wilcox; John Lazo; Brian I Carr
Involvement of Cdc25A phosphatase in Hep3B hepatoma cell growth inhibition induced by novel K vitamin analogs.
Cancer research 2001;61(19):7211-6.
2000: Ziqiu Wang; Meifang Wang; Brian I Carr
Involvement of hepatocyte epidermal growth factor receptor mediated activation of mitogen-activated protein kinase signaling pathways in response to growth inhibition by a novel K vitamin.
Journal of cellular physiology 2000;183(3):338-46.
1998: Y Nishikawa; Meifang Wang; Brian I Carr
Changes in TGF-beta receptors of rat hepatocytes during primary culture and liver regeneration: increased expression of TGF-beta receptors associated with increased sensitivity to TGF-beta-mediated growth inhibition.
Journal of cellular physiology 1998;176(3):612-23.