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Rong Wang

Research Profile

Chemicals & Drugs

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Xulun Zhang; Rong Wang; Kwangwook Ahn; Georgia Dolios; Robert J Hoey; Takeshi Ikeuchi; Akiko Koide; Shohei Koide; Brenda Leung; Yue-Ming Li; Guoqing Lin; Marcin Paduch; Sangram S Sisodia
Identification of a tetratricopeptide repeat-like domain in the nicastrin subunit of γ-secretase using synthetic antibodies.
Serene Keilani; Gadiparthi N Rao; Elizabeth A Thomas; Rong Wang; Heike Beck; Alexey Bogush; Samira Chandwani; Georgia Dolios; Antonis K Hatzopoulos; Michelle E Ehrlich
Egr-1 induces DARPP-32 expression in striatal medium spiny neurons via a conserved intragenic element.
Anastasia Liapis; Rong Wang; Fannie W Chen; Joanna P Davies; Yiannis A Ioannou
MLN64 transport to the late endosome is regulated by binding to 14-3-3 via a non-canonical binding site.

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All Publications

2012: Xulun Zhang; Rong Wang; Kwangwook Ahn; Georgia Dolios; Robert J Hoey; Takeshi Ikeuchi; Akiko Koide; Shohei Koide; Brenda Leung; Yue-Ming Li; Guoqing Lin; Marcin Paduch; Sangram S Sisodia
Identification of a tetratricopeptide repeat-like domain in the nicastrin subunit of γ-secretase using synthetic antibodies.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(22):8534-9.
2012: Serene Keilani; Gadiparthi N Rao; Elizabeth A Thomas; Rong Wang; Heike Beck; Alexey Bogush; Samira Chandwani; Georgia Dolios; Antonis K Hatzopoulos; Michelle E Ehrlich
Egr-1 induces DARPP-32 expression in striatal medium spiny neurons via a conserved intragenic element.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(20):6808-18.
2012: Anastasia Liapis; Rong Wang; Fannie W Chen; Joanna P Davies; Yiannis A Ioannou
MLN64 transport to the late endosome is regulated by binding to 14-3-3 via a non-canonical binding site.
PloS one 2012;7(4):e34424.
2010: monica fernandez-monreal; Twethida Oung; Hugo H Hanson; Robert O'Leary; William G Janssen; Georgia Dolios; Rong Wang; Greg R Phillips
γ-protocadherins are enriched and transported in specialized vesicles associated with the secretory pathway in neurons.
The European journal of neuroscience 2010;32(6):921-31.
2009: Noura S Abul-Husn; Ittai Bushlin; José A Morón; Sherry L Jenkins; Georgia Dolios; Rong Wang; Ravi Iyengar; Avi Ma'ayan; Lakshmi A Devi
Systems approach to explore components and interactions in the presynapse.
Proteomics 2009;9(12):3303-15.
2009: Radda Rusinova; Yu-Ming Albert Shen; Georgia Dolios; Julio Padovan; Heyi Yang; MA Kirchberger; Rong Wang; Diomedes E Logothetis
Mass spectrometric analysis reveals a functionally important PKA phosphorylation site in a Kir3 channel subunit.
Pflügers Archiv : European journal of physiology 2009;458(2):303-14.
2009: Jinzhou Tian; Jing Shi; Leiming Zhang; Junxiang Yin; Quan Hu; Yi Xu; Shuli Sheng; Pengwen Wang; Ying Ren; Rong Wang; Yongyan Wang
GEPT extract reduces Abeta deposition by regulating the balance between production and degradation of Abeta in APPV717I transgenic mice.
Current Alzheimer research 2009;6(2):118-31.
2009: Marc Walter; Fannie W Chen; Farshad Tamari; Rong Wang; Yiannis A Ioannou
Endosomal lipid accumulation in NPC1 leads to inhibition of PKC, hypophosphorylation of vimentin and Rab9 entrapment.
Biology of the cell / under the auspices of the European Cell Biology Organization 2009;101(3):141-52.
2009: Bolleddula Jayaprakasam; Srinivasulu Doddaga; Rong Wang; Daniel Holmes; Joseph Goldfarb; Xiu-Min Li
Licorice flavonoids inhibit eotaxin-1 secretion by human fetal lung fibroblasts in vitro.
Journal of agricultural and food chemistry 2009;57(3):820-5.
2009: Leiming Zhang; Jinzhou Tian; Junxiang Yin; Jing Shi; Pengwen Wang; Rong Wang; Quan Hu; Zhiwei Zhao; Zhijuan Ji; Ying Ren
[Effect of GEPT extracts on spatial learning ability of APPV717I transgenic mice at early stage of dementia and its possible mechanism].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 2009;34(4):428-32.
2008: Vicki Betts; Malcolm Leissring; Georgia Dolios; Rong Wang; Dennis J Selkoe; Dominic M Walsh
Aggregation and catabolism of disease-associated intra-Abeta mutations: reduced proteolysis of AbetaA21G by neprilysin.
Neurobiology of disease 2008;31(3):442-50.
2008: Pamela Osenkowski; Wenjuan Ye; Rong Wang; Michael S Wolfe; Dennis J Selkoe
Direct and potent regulation of gamma-secretase by its lipid microenvironment.
The Journal of biological chemistry 2008;283(33):22529-40.
2008: Xinsong Xu; Antonio Sarikas; Dora C Dias-Santagata; Georgia Dolios; Pascal J Lafontant; Shih-Chong Tsai; Wuqiang Zhu; Hidehiro Nakajima; Hisako O Nakajima; Loren J Field; Rong Wang; Zhen-Qiang Pan
The CUL7 E3 ubiquitin ligase targets insulin receptor substrate 1 for ubiquitin-dependent degradation.
Molecular cell 2008;30(4):403-14.
2008: Kosj Yamoah; Alina Brebene; Ramkumarie Baliram; Kenji Inagaki; Georgia Dolios; Ario Arabi; Rinosha Majeed; Hitoshi Amano; Rong Wang; Robert Yanagisawa; Etsuko Abe
High-mobility group box proteins modulate tumor necrosis factor-alpha expression in osteoclastogenesis via a novel deoxyribonucleic acid sequence.
Molecular endocrinology (Baltimore, Md.) 2008;22(5):1141-53.
2008: Amitabha Majumdar; Haeyong Chung; Georgia Dolios; Rong Wang; Nikiya Asamoah; Peter Lobel; Frederick R Maxfield
Degradation of fibrillar forms of Alzheimer's amyloid beta-peptide by macrophages.
Neurobiology of aging 2008;29(5):707-15.
2007: Sarju Patel; Ehsan Hazrati; Natalia Cheshenko; Benjamin Galen; Heyi Yang; Esmeralda Guzman; Rong Wang; Betsy C Herold; Marla Keller
Seminal plasma reduces the effectiveness of topical polyanionic microbicides.
The Journal of infectious diseases 2007;196(9):1394-402.
2007: Claudia M Litterst; Anastasios Georgakopoulos; Junichi Shioi; Enrico Ghersi; Thomas Wisniewski; Rong Wang; Andreas Ludwig; Nikolaos K Robakis
Ligand binding and calcium influx induce distinct ectodomain/gamma-secretase-processing pathways of EphB2 receptor.
The Journal of biological chemistry 2007;282(22):16155-63.
2007: José A Morón; Noura Abul-Husn; Raphael Rozenfeld; Georgia Dolios; Rong Wang; Lakshmi A Devi
Morphine administration alters the profile of hippocampal postsynaptic density-associated proteins: a proteomics study focusing on endocytic proteins.
Molecular & cellular proteomics : MCP 2007;6(1):29-42.
2006: Tatyana Adayev; Mo-Chou Chen-Hwang; Noriko Murakami; Rong Wang; Yu-Wen Hwang
MNB/DYRK1A phosphorylation regulates the interactions of synaptojanin 1 with endocytic accessory proteins.
Biochemical and biophysical research communications 2006;351(4):1060-5.
2006: Samir Kumar-Singh; Jessie Theuns; Bianca Van Broeck; Daniel Pirici; Krist'l Vennekens; Ellen Corsmit; Marc Cruts; Bart Dermaut; Rong Wang; Christine Van Broeckhoven
Mean age-of-onset of familial alzheimer disease caused by presenilin mutations correlates with both increased Abeta42 and decreased Abeta40.
Human mutation 2006;27(7):686-95.
2006: Chengmin Qian; Xueqi Wang; Karishma L Manzur; Amjad Farooq; Lei Zeng; Rong Wang; Ming-Ming Zhou
Structural insights of the specificity and catalysis of a viral histone H3 lysine 27 methyltransferase.
Journal of molecular biology 2006;359(1):86-96.
2005: Dan Li; Steven Yea; Georgia Dolios; John A Martignetti; Goutham Narla; Rong Wang; Martin J Walsh; Scott L Friedman
Regulation of Kruppel-like factor 6 tumor suppressor activity by acetylation.
Cancer research 2005;65(20):9216-25.
2005: Giuseppina Tesco; Andrea Ginestroni; Mikko Hiltunen; Minji Kim; Georgia Dolios; Bradley T Hyman; Rong Wang; Oksana Berezovska; Rudolph E Tanzi
APP substitutions V715F and L720P alter PS1 conformation and differentially affect Abeta and AICD generation.
Journal of neurochemistry 2005;95(2):446-56.
2005: Dmitriy Zamarin; Adolfo García-Sastre; Xiaoyao Xiao; Rong Wang; Peter Palese
Influenza virus PB1-F2 protein induces cell death through mitochondrial ANT3 and VDAC1.
PLoS pathogens 2005;1(1):e4.
2005: Gilbert S Omenn; David States; Marcin Adamski; Thomas W Blackwell; Rajasree Menon; Henning Hermjakob; Rolf Apweiler; Brian B Haab; Richard J Simpson; James S Eddes; Eugene A Kapp; Robert L Moritz; Daniel W Chan; Alex J Rai; Arie Admon; Ruedi Aebersold; Jimmy Eng; William S Hancock; Stanley A Hefta; Helmut Meyer; Young-Ki Paik; Jong-Shin Yoo; Peipei Ping; Joel G Pounds; Joshua Adkins; Xiaohong Qian; Rong Wang; Valerie Wasinger; Chi Yue Wu; Xiaohang Zhao; Rong Zeng; Alexander Archakov; Akira Tsugita; Ilan Beer; Akhilesh Pandey; Michael Pisano; Philip C Andrews; Harald Tammen; David W Speicher; Samir M Hanash
Overview of the HUPO Plasma Proteome Project: results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly-available database.
Proteomics 2005;5(13):3226-45.
2005: Eileen McGowan; Fiona Pickford; Jungsu Kim; Luisa Onstead; Jason Eriksen; Cindy Yu; Lisa Skipper; Michael Murphy; Jenny Beard; Pritam Das; Karen Jansen; Michael W DeLucia; Wen-Lang Lin; Georgia Dolios; Rong Wang; Christopher B Eckman; dennis dickson; Michael Hutton; John Hardy; todd golde
Abeta42 is essential for parenchymal and vascular amyloid deposition in mice.
Neuron 2005;47(2):191-9.
2005: Yoshifumi Nakaya; Takuya Yamane; Hirohisa Shiraishi; Hua-Qin Wang; Etsuro Matsubara; Toru Sato; Georgia Dolios; Rong Wang; Bart De Strooper; Mikio Shoji; Hiroto Komano; Katsuhiko Yanagisawa; Yasuo Ihara; Paul E Fraser; Peter St George-Hyslop; Masaki Nishimura
Random mutagenesis of presenilin-1 identifies novel mutants exclusively generating long amyloid beta-peptides.
The Journal of biological chemistry 2005;280(19):19070-7.
2005: Jun Wang; Lap Ho; Weiping Qin; Anne B Rocher; Ilana Seror; Nelson Humala; Kruti Maniar; Georgia Dolios; Rong Wang; Patrick R Hof; Giulio Maria Pasinetti
Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer's disease.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(6):659-61.
2005: Yue Qi-Takahara; Maho Morishima-Kawashima; Yu Tanimura; Georgia Dolios; Naoko Hirotani; Yuko Horikoshi; Fuyuki Kametani; Masahiro Maeda; Takaomi C Saido; Rong Wang; Yasuo Ihara
Longer forms of amyloid beta protein: implications for the mechanism of intramembrane cleavage by gamma-secretase.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(2):436-45.
2004: Dawn L Brasaemle; Georgia Dolios; Lawrence Shapiro; Rong Wang
Proteomic analysis of proteins associated with lipid droplets of basal and lipolytically stimulated 3T3-L1 adipocytes.
The Journal of biological chemistry 2004;279(45):46835-42.
2004: Silva Hecimovic; Jun Wang; Georgia Dolios; Maribel Martinez; Rong Wang; Alison Goate
Mutations in APP have independent effects on Abeta and CTFgamma generation.
Neurobiology of disease 2004;17(2):205-18.
2004: Vidya Subramanian; Alexis Rothenberg; Carlos Gomez; Alex W Cohen; Anne Garcia; Sucharita Bhattacharyya; Lawrence Shapiro; Georgia Dolios; Rong Wang; Michael P Lisanti; Dawn L Brasaemle
Perilipin A mediates the reversible binding of CGI-58 to lipid droplets in 3T3-L1 adipocytes.
The Journal of biological chemistry 2004;279(40):42062-71.
2004: Alan R Schoenfeld; Sarah Apgar; Georgia Dolios; Rong Wang; Stuart A Aaronson
BRCA2 is ubiquitinated in vivo and interacts with USP11, a deubiquitinating enzyme that exhibits prosurvival function in the cellular response to DNA damage.
Molecular and cellular biology 2004;24(17):7444-55.
2004: Yu Huang; Mo-Chou Chen-Hwang; Georgia Dolios; Noriko Murakami; Júlio C Padovan; Rong Wang; Yu-Wen Hwang
Mnb/Dyrk1A phosphorylation regulates the interaction of dynamin 1 with SH3 domain-containing proteins.
Biochemistry 2004;43(31):10173-85.
2004: Patrick C Fraering; Wenjuan Ye; Jean-Marc Strub; Georgia Dolios; Matthew J LaVoie; Beth L Ostaszewski; Alain Van Dorsselaer; Rong Wang; Dennis J Selkoe; Michael S Wolfe
Purification and characterization of the human gamma-secretase complex.
Biochemistry 2004;43(30):9774-89.
2003: Ephraim Sehayek; Rong Wang; Jennie G Ono; Vadim S Zinchuk; Elizabeth M Duncan; Sarah Shefer; Dennis E Vance; Meenakshisundaram Ananthanarayanan; Brian T Chait; Jan L Breslow
Localization of the PE methylation pathway and SR-BI to the canalicular membrane: evidence for apical PC biosynthesis that may promote biliary excretion of phospholipid and cholesterol.
Journal of lipid research 2003;44(9):1605-13.
2003: Kenneth Wu; Kosj Yamoah; Georgia Dolios; Tudeviin Gan-Erdene; Peilin Tan; Angus Chen; Chee-Gun Lee; Ning Wei; Keith Wilkinson; Rong Wang; Zhen-Qiang Pan
DEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1.
The Journal of biological chemistry 2003;278(31):28882-91.
2003: John B J Kwok; Linda Truong; William S Brooks; Georgia Dolios; Hanna Laudon; Ohoshi Murayama; Marianne Hallupp; Renee F Badenhop; James Vickers; Rong Wang; Jan Naslund; Akihiko Takashima; Sam Gandy; Peter R Schofield
Presenilin-1 mutation L271V results in altered exon 8 splicing and Alzheimer's disease with non-cored plaques and no neuritic dystrophy.
The Journal of biological chemistry 2003;278(9):6748-54.
2003: Takeshi Ikeuchi; Georgia Dolios; Seong-Hun Kim; Rong Wang; Sangram S Sisodia
Familial Alzheimer disease-linked presenilin 1 variants enhance production of both Abeta 1-40 and Abeta 1-42 peptides that are only partially sensitive to a potent aspartyl protease transition state inhibitor of "gamma-secretase".
The Journal of biological chemistry 2003;278(9):7010-8.
2002: Dora C Dias; Georgia Dolios; Rong Wang; Zhen-Qiang Pan
CUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(26):16601-6.
2002: Samir Kumar-Singh; Patrick Cras; Rong Wang; John M Kros; John C van Swieten; Ursula Lübke; Chantal Ceuterick; Sally Serneels; Krist'l Vennekens; Jean-Pierre Timmermans; Eric Van Marck; Jean-Jacques Martin; C.M. Duijn; Christine Van Broeckhoven
Dense-core senile plaques in the Flemish variant of Alzheimer's disease are vasocentric.
The American journal of pathology 2002;161(2):507-20.
2002: Asesh Banerjee; Rong Wang; Sherry L Supernavage; Salil K Ghosh; James Parker; Nisha F Ganesh; Peng George Wang; Sunita Gulati; Peter A Rice
Implications of phase variation of a gene (pgtA) encoding a pilin galactosyl transferase in gonococcal pathogenesis.
The Journal of experimental medicine 2002;196(2):147-62.
2002: Jimin Zhang; Wenjuan Ye; Rong Wang; Michael S Wolfe; Barry D Greenberg; Dennis J Selkoe
Proteolysis of chimeric beta-amyloid precursor proteins containing the Notch transmembrane domain yields amyloid beta-like peptides.
The Journal of biological chemistry 2002;277(17):15069-75.
2002: Michael Murphy; Sacha N Uljon; todd golde; Rong Wang
FAD-linked mutations in presenilin 1 alter the length of Abeta peptides derived from betaAPP transmembrane domain mutants.
Biochimica et biophysica acta 2002;1586(2):199-209.
2002: Stefan F Lichtenthaler; Dirk Beher; Heike S Grimm; Rong Wang; Mark S Shearman; Colin L Masters; Konrad Beyreuther
The intramembrane cleavage site of the amyloid precursor protein depends on the length of its transmembrane domain.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(3):1365-70.
2001: Chunjiang Yu; Seong-Hun Kim; Takeshi Ikeuchi; Huaxi Xu; L Gasparini; Rong Wang; Sangram S Sisodia
Characterization of a presenilin-mediated amyloid precursor protein carboxyl-terminal fragment gamma. Evidence for distinct mechanisms involved in gamma -secretase processing of the APP and Notch1 transmembrane domains.
The Journal of biological chemistry 2001;276(47):43756-60.
2001: Sascha Weggen; Jason Eriksen; Pritam Das; Sarah A Sagi; Rong Wang; Claus U Pietrzik; Kirk Findlay; Tawnya E Smith; Michael Murphy; T Bulter; David E Kang; NR Marquez-Sterling; todd golde; Edward H Koo
A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity.
Nature 2001;414(6860):212-6.
2001: Patrick A Lewis; S Piper; Matt Baker; Luisa Onstead; Michael Murphy; John Hardy; Rong Wang; Eileen McGowan; todd golde
Expression of BRI-amyloid beta peptide fusion proteins: a novel method for specific high-level expression of amyloid beta peptides.
Biochimica et biophysica acta 2001;1537(1):58-62.
2000: Chris McLendon; T Xin; Chewki Ziani-Cherif; Michael Murphy; Kirk Findlay; Patrick A Lewis; Inga Pinnix; Kumar Sambamurti; Rong Wang; Abdul Fauq; todd golde
Cell-free assays for gamma-secretase activity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(15):2383-6.
2000: Samir Kumar-Singh; Chris De Jonghe; Marc Cruts; R Kleinert; Rong Wang; Marc Mercken; Bart De Strooper; hugo vanderstichele; Ann Löfgren; I Vanderhoeven; Hubert Backhovens; Eugeen Vanmechelen; P M Kroisel; Christine Van Broeckhoven
Nonfibrillar diffuse amyloid deposition due to a gamma(42)-secretase site mutation points to an essential role for N-truncated A beta(42) in Alzheimer's disease.
Human molecular genetics 2000;9(18):2589-98.
2000: Michael Murphy; Sacha N Uljon; Paul E Fraser; Abdul Fauq; H A Lookingbill; Kirk Findlay; Tawnya E Smith; Patrick A Lewis; D C McLendon; Rong Wang; todd golde
Presenilin 1 regulates pharmacologically distinct gamma -secretase activities. Implications for the role of presenilin in gamma -secretase cleavage.
The Journal of biological chemistry 2000;275(34):26277-84.
2000: M Jensen; Tobias Hartmann; Benita Engvall; Rong Wang; S N Uljon; Kristina Sennvik; Jan Näslund; F Muehlhauser; C Nordstedt; Konrad Beyreuther; Lars Lannfelt
Quantification of Alzheimer amyloid beta peptides ending at residues 40 and 42 by novel ELISA systems.
Molecular medicine (Cambridge, Mass.) 2000;6(4):291-302.
2000: Seong-Hun Kim; Rong Wang; David J Gordon; J Bass; Donald F Steiner; Gopal Thinakaran; David G Lynn; Stephen C Meredith; Sangram S Sisodia
Familial British dementia: expression and metabolism of BRI.
Annals of the New York Academy of Sciences 2000;920():93-9.
2000: Michael Murphy; Rong Wang; Paul E Fraser; Abdul Fauq; todd golde
An empirical model of gamma-secretase activity.
Annals of the New York Academy of Sciences 2000;920():233-40.
1999: Rong Wang; Brian T Chait; I Wolf; Ronald A Kohanski; Christopher Cardozo
Lysozyme degradation by the bovine multicatalytic proteinase complex (proteasome): evidence for a nonprocessive mode of degradation.
Biochemistry 1999;38(44):14573-81.
1999: Seong-Hun Kim; Rong Wang; David J Gordon; J Bass; Donald F Steiner; David G Lynn; Gopal Thinakaran; Stephen C Meredith; Sangram S Sisodia
Furin mediates enhanced production of fibrillogenic ABri peptides in familial British dementia.
Nature neuroscience 1999;2(11):984-8.
1999: Eileen McGowan; S Sanders; Takeshi Iwatsubo; A Takeuchi; Takaomi C Saido; Cynthia Zehr; X Yu; Sacha N Uljon; Rong Wang; D M A Mann; dennis dickson; karen duff
Amyloid phenotype characterization of transgenic mice overexpressing both mutant amyloid precursor protein and mutant presenilin 1 transgenes.
Neurobiology of disease 1999;6(4):231-44.
1999: T Mizuno; M Nakata; H Naiki; Makoto Michikawa; Rong Wang; Christian Haass; Katsuhiko Yanagisawa
Cholesterol-dependent generation of a seeding amyloid beta-protein in cell culture.
The Journal of biological chemistry 1999;274(21):15110-4.
1999: Michael Murphy; L J Hickman; Christopher B Eckman; Sacha N Uljon; Rong Wang; todd golde
gamma-Secretase, evidence for multiple proteolytic activities and influence of membrane positioning of substrate on generation of amyloid beta peptides of varying length.
The Journal of biological chemistry 1999;274(17):11914-23.
1999: Stefan F Lichtenthaler; Rong Wang; Heike S Grimm; S N Uljon; Colin L Masters; Konrad Beyreuther
Mechanism of the cleavage specificity of Alzheimer's disease gamma-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor protein.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):3053-8.
1999: Hiroto Komano; S Sudoh; Yuuki Kawamura; Rong Wang; Katsuhiko Yanagisawa
Implications of presenilin 1 mutations in Alzheimer's disease.
Mechanisms of ageing and development 1999;107(3):281-98.
1999: Jeffery J Anderson; Greg Holtz; P P Baskin; Rong Wang; L Mazzarelli; Steven L Wagner; F Menzaghi
Reduced cerebrospinal fluid levels of alpha-secretase-cleaved amyloid precursor protein in aged rats: correlation with spatial memory deficits.
Neuroscience 1999;93(4):1409-20.
1998: Gunnar K Gouras; H Xu; J N Jovanovic; Joseph Buxbaum; Rong Wang; Paul Greengard; Norman Richard Relkin; Sam Gandy
Generation and regulation of beta-amyloid peptide variants by neurons.
Journal of neurochemistry 1998;71(5):1920-5.
1998: S Sudoh; Yuuki Kawamura; S Sato; Rong Wang; Takaomi C Saido; F Oyama; Y Sakaki; Hiroto Komano; Katsuhiko Yanagisawa
Presenilin 1 mutations linked to familial Alzheimer's disease increase the intracellular levels of amyloid beta-protein 1-42 and its N-terminally truncated variant(s) which are generated at distinct sites.
Journal of neurochemistry 1998;71(4):1535-43.
1997: P Chen; J D Choi; Rong Wang; Robert J Cotter; Susan Michaelis
A novel a-factor-related peptide of Saccharomyces cerevisiae that exits the cell by a Ste6p-independent mechanism.
Molecular biology of the cell 1997;8(7):1273-91.
1997: Huaxi Xu; D Sweeney; Rong Wang; Gopal Thinakaran; Amy Lo; Sangram S Sisodia; Paul Greengard; Sam Gandy
Generation of Alzheimer beta-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):3748-52.
1996: Rong Wang; D Sweeney; Sam Gandy; Sangram S Sisodia
The profile of soluble amyloid beta protein in cultured cell media. Detection and quantification of amyloid beta protein and variants by immunoprecipitation-mass spectrometry.
The Journal of biological chemistry 1996;271(50):31894-902.
1996: David R Borchelt; Gopal Thinakaran; Christopher B Eckman; Michael K Lee; F Davenport; T Ratovitsky; CM Prada; G Kim; S Seekins; Debra Yager; Hilda H Slunt; Rong Wang; M Seeger; Allan Levey; Sam Gandy; Neal G Copeland; Nancy A Jenkins; Donald L Price; Steven G Younkin; Sangram S Sisodia
Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo.
Neuron 1996;17(5):1005-13.
1996: Rong Wang; Brian T Chait
Posttranslational modifications analyzed by automated protein ladder sequencing.
Methods in molecular biology (Clifton, N.J.) 1996;61():161-70.
1996: J Z Chou; Brian T Chait; Rong Wang; Mary Jeanne Kreek
Differential biotransformation of dynorphin A (1-17) and dynorphin A (1-13) peptides in human blood, ex vivo.
Peptides 1996;17(6):983-90.
1994: Rong Wang; Brian T Chait
High-accuracy mass measurement as a tool for studying proteins.
Current opinion in biotechnology 1994;5(1):77-84.
1993: Brian T Chait; Rong Wang; Ronald C Beavis; S B Kent
Protein ladder sequencing.
Science (New York, N.Y.) 1993;262(5130):89-92.
1993: Alex Roher; Jonathan D Lowenson; Steven Clarke; C Wolkow; Rong Wang; Robert J Cotter; I M Reardon; H A Zürcher-Neely; Robert L Heinrikson; Melvyn Ball
Structural alterations in the peptide backbone of beta-amyloid core protein may account for its deposition and stability in Alzheimer's disease.
The Journal of biological chemistry 1993;268(5):3072-83.
1992: J M Pasternack; M R Palmert; M Usiak; Rong Wang; H Zurcher-Neely; P A Gonzalez-De Whitt; M B Fairbanks; T Cheung; D Blades; Robert L Heinrikson
Alzheimer's disease and control brain contain soluble derivatives of the amyloid protein precursor that end within the beta amyloid protein region.
Biochemistry 1992;31(44):10936-40.
1992: K R Myers; J T Ulrich; N Qureshi; K Takayama; Rong Wang; L Chen; W B Emary; Robert J Cotter
Preparation and characterization of biologically active 6'-O-(6-aminocaproyl)-4'-O-monophosphoryl lipid A and its conjugated derivative.
Bioconjugate chemistry 1992;3(6):540-8.
1991: H Masoud; Susan Weintraub; Rong Wang; Robert J Cotter; Stanley C Holt
Investigation of the structure of lipid A from Actinobacillus actinomycetemcomitans strain Y4 and human clinical isolate PO 1021-7.
European journal of biochemistry / FEBS 1991;200(3):775-81.
1991: Rong Wang; J F Meschia; Robert J Cotter; Sangram S Sisodia
Secretion of the beta/A4 amyloid precursor protein. Identification of a cleavage site in cultured mammalian cells.
The Journal of biological chemistry 1991;266(25):16960-4.
1991: N Qureshi; K Takayama; K C Meyer; Theo N Kirkland; C Allen Bush; L Chen; Rong Wang; Robert J Cotter
Chemical reduction of 3-oxo and unsaturated groups in fatty acids of diphosphoryl lipid A from the lipopolysaccharide of Rhodopseudomonas sphaeroides. Comparison of biological properties before and after reduction.
The Journal of biological chemistry 1991;266(10):6532-8.
1990: Rong Wang; L Chen; Robert J Cotter
Effects of peptide hydrophobicity and charge state on molecular ion yields in plasma desorption mass spectrometry.
Analytical chemistry 1990;62(15):1700-5.
1988: S E Unger; J Brange; A Lauritano; Plamen A Demirev; Rong Wang; Robert J Cotter
Fast atom bombardment and plasma desorption mass spectrometry of degraded insulins in intermediate and long-acting preparations.
Rapid communications in mass spectrometry : RCM 1988;2(6):109-12.
1988: Rong Wang; Robert J Cotter; T Y Lin; M Laskowski
Plasma desorption mass spectrometric analysis of glycosylated ovomucoid third domain from Japanese quail.
Rapid communications in mass spectrometry : RCM 1988;2(4):71-3.
1987: V L Vaughn; Rong Wang; Catherine Fenselau; H B White
Phosphorylation heterogeneity of tryptic phosphopeptides of chicken riboflavin-binding protein.
Biochemical and biophysical research communications 1987;147(1):115-9.