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Wengong Wang

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TOP 3
Wengong Wang
Regulatory RNA-binding proteins in senescence.
Xiaotian Zhang; Junyue Xing; Jie Yi; Minqwei Yu; Myriam Gorospe; Zhenyun Liu; Yongfeng Shang; Hao Tang; Tanjun Tong; Wengong Wang
The tRNA methyltransferase NSun2 stabilizes p16INK⁴ mRNA by methylating the 3'-untranslated region of p16.
Fang Xu; Xiaotian Zhang; Yutao Lei; Xinwen Liu; Zhenyun Liu; Tanjun Tong; Wengong Wang
Loss of repression of HuR translation by miR-16 may be responsible for the elevation of HuR in human breast carcinoma.

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All Publications

2012: Wengong Wang
Regulatory RNA-binding proteins in senescence.
Ageing research reviews 2012;11(4):485-90.
2012: Xiaotian Zhang; Junyue Xing; Jie Yi; Minqwei Yu; Myriam Gorospe; Zhenyun Liu; Yongfeng Shang; Hao Tang; Tanjun Tong; Wengong Wang
The tRNA methyltransferase NSun2 stabilizes p16INK⁴ mRNA by methylating the 3'-untranslated region of p16.
Nature communications 2012;3():712.
2010: Fang Xu; Xiaotian Zhang; Yutao Lei; Xinwen Liu; Zhenyun Liu; Tanjun Tong; Wengong Wang
Loss of repression of HuR translation by miR-16 may be responsible for the elevation of HuR in human breast carcinoma.
Journal of cellular biochemistry 2010;111(3):727-34.
2010: Na Chang; Jie Yi; Gaier Guo; X Liu; Yongfeng Shang; Tanjun Tong; Qinghua Cui; Ming Zhan; Myriam Gorospe; Wengong Wang
HuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay.
Molecular and cellular biology 2010;30(15):3875-86.
2010: Jie Yi; Na Chang; Xinwen Liu; Gaier Guo; Lixiang Xue; Tanjun Tong; Myriam Gorospe; Wengong Wang
Reduced nuclear export of HuR mRNA by HuR is linked to the loss of HuR in replicative senescence.
Nucleic acids research 2010;38(5):1547-58.
2005: Wengong Wang; Jennifer L Martindale; Xiaoling Yang; Francis J Chrest; Myriam Gorospe
Increased stability of the p16 mRNA with replicative senescence.
EMBO reports 2005;6(2):158-64.
2004: Xiaoling Yang; Wengong Wang; JINSHUI FAN; Ashish Lal; Dongmei Yang; Heping Cheng; Myriam Gorospe
Prostaglandin A2-mediated stabilization of p21 mRNA through an ERK-dependent pathway requiring the RNA-binding protein HuR.
The Journal of biological chemistry 2004;279(47):49298-306.
2004: Wengong Wang; Xiaoling Yang; Tomoko Kawai; Isabel López De Silanes; Krystyna Mazan-Mamczarz; Peili Chen; YuhMin Chook; Christina Quensel; Matthias Köhler; Myriam Gorospe
AMP-activated protein kinase-regulated phosphorylation and acetylation of importin alpha1: involvement in the nuclear import of RNA-binding protein HuR.
The Journal of biological chemistry 2004;279(46):48376-88.
2003: Stefanie Galban; Jennifer L Martindale; Krystyna Mazan-Mamczarz; Isabel López De Silanes; JINSHUI FAN; Wengong Wang; Jochen Decker; Myriam Gorospe
Influence of the RNA-binding protein HuR in pVHL-regulated p53 expression in renal carcinoma cells.
Molecular and cellular biology 2003;23(20):7083-95.
2003: Wengong Wang; Xiaoling Yang; Isabel López De Silanes; David Carling; Myriam Gorospe
Increased AMP:ATP ratio and AMP-activated protein kinase activity during cellular senescence linked to reduced HuR function.
The Journal of biological chemistry 2003;278(29):27016-23.
2002: JINSHUI FAN; Xiaoling Yang; Wengong Wang; William H Wood; Kevin G Becker; Myriam Gorospe
Global analysis of stress-regulated mRNA turnover by using cDNA arrays.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(16):10611-6.
2002: Wengong Wang; JINSHUI FAN; Xiaoling Yang; Stefanie Fürer-Galban; Isabel Lopez de Silanes; Cayetano von Kobbe; Jia Guo; Steve N Georas; Fabienne Foufelle; D Grahame Hardie; David Carling; Myriam Gorospe
AMP-activated kinase regulates cytoplasmic HuR.
Molecular and cellular biology 2002;22(10):3425-36.
2001: Wengong Wang; Xiaoling Yang; V J Cristofalo; Nikki J Holbrook; Myriam Gorospe
Loss of HuR is linked to reduced expression of proliferative genes during replicative senescence.
Molecular and cellular biology 2001;21(17):5889-98.
2000: Zuqin Nie; Yutong Xue; Dafeng Yang; Sharleen Zhou; Bonnie J Deroo; Trevor K Archer; Wengong Wang
A specificity and targeting subunit of a human SWI/SNF family-related chromatin-remodeling complex.
Molecular and cellular biology 2000;20(23):8879-88.
2000: Yutong Xue; J C Canman; C S Lee; Z Nie; Dongmei Yang; G T Moreno; Mary K Young; E D Salmon; Wengong Wang
The human SWI/SNF-B chromatin-remodeling complex is related to yeast rsc and localizes at kinetochores of mitotic chromosomes.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(24):13015-20.
2000: S Lin; Wengong Wang; Gerald M Wilson; Xiaoling Yang; Gary Brewer; Nikki J Holbrook; Myriam Gorospe
Down-regulation of cyclin D1 expression by prostaglandin A(2) is mediated by enhanced cyclin D1 mRNA turnover.
Molecular and cellular biology 2000;20(21):7903-13.
2000: Wengong Wang; M Craig Caldwell; S Lin; Henry Furneaux; Myriam Gorospe
HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation.
The EMBO journal 2000;19(10):2340-50.
2000: Wengong Wang; Henry Furneaux; H Cheng; M Craig Caldwell; Dorothy Hutter; Yusen Liu; Nikki J Holbrook; Myriam Gorospe
HuR regulates p21 mRNA stabilization by UV light.
Molecular and cellular biology 2000;20(3):760-9.
1998: Yutong Xue; J Wong; G T Moreno; Mary K Young; J Côté; Wengong Wang
NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities.
Molecular cell 1998;2(6):851-61.