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Xuping Wang

Research Profile

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Chemicals & Drugs

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TOP 3
Juyong Brian Kim; Lawrence W Castellani; Sarada Charugundla; Mete Civelek; Andres Deluna; Hieronim Jakobowski; Imran N Mungrue; Luz Orozco; Delila Pouldar; Marta Rusek; Christine Vu; Xuping Wang; Judy Wu; Aldons J Lusis
Effect of 9p21.3 coronary artery disease locus neighboring genes on atherosclerosis in mice.
Cynthia Hong; Aldons J Lusis; Susan Realegeno; Srinivasa T Reddy; Xin Rong; Jon Salazar; Rajendra K Tangirala; Rima Boyadjian; Michelle N Bradley; Lawrence W Castellani; Alan M Fogelman; Victor Grijalva; Brian J Van Lenten; Alan Wagner; Xuping Wang; Peter Tontonoz
LXRα is uniquely required for maximal reverse cholesterol transport and atheroprotection in ApoE-deficient mice.
Berenice Barajas; Nam Che; Fen Yin; Amir Rowshanrad; Luz D Orozco; Ke Wei Gong; Xuping Wang; Lawrence W Castellani; Karen Reue; Aldons J Lusis; Jesus A Araujo
NF-E2-related factor 2 promotes atherosclerosis by effects on plasma lipoproteins and cholesterol transport that overshadow antioxidant protection.

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All Publications

2012: Juyong Brian Kim; Lawrence W Castellani; Sarada Charugundla; Mete Civelek; Andres Deluna; Hieronim Jakobowski; Imran N Mungrue; Luz Orozco; Delila Pouldar; Marta Rusek; Christine Vu; Xuping Wang; Judy Wu; Aldons J Lusis
Effect of 9p21.3 coronary artery disease locus neighboring genes on atherosclerosis in mice.
Circulation 2012;126(15):1896-906.
2012: Cynthia Hong; Aldons J Lusis; Susan Realegeno; Srinivasa T Reddy; Xin Rong; Jon Salazar; Rajendra K Tangirala; Rima Boyadjian; Michelle N Bradley; Lawrence W Castellani; Alan M Fogelman; Victor Grijalva; Brian J Van Lenten; Alan Wagner; Xuping Wang; Peter Tontonoz
LXRα is uniquely required for maximal reverse cholesterol transport and atheroprotection in ApoE-deficient mice.
Journal of lipid research 2012;53(6):1126-33.
2011: Berenice Barajas; Nam Che; Fen Yin; Amir Rowshanrad; Luz D Orozco; Ke Wei Gong; Xuping Wang; Lawrence W Castellani; Karen Reue; Aldons J Lusis; Jesus A Araujo
NF-E2-related factor 2 promotes atherosclerosis by effects on plasma lipoproteins and cholesterol transport that overshadow antioxidant protection.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(1):58-66.
2010: Yucheng Yao; Brian J Bennett; Xuping Wang; Michael E Rosenfeld; Cecilia Giachelli; Aldons J Lusis; Kristina I Boström
Inhibition of bone morphogenetic proteins protects against atherosclerosis and vascular calcification.
Circulation research 2010;107(4):485-94.
2010: Zory Shaposhnik; Xuping Wang; Aldons J Lusis
Arterial colony stimulating factor-1 influences atherosclerotic lesions by regulating monocyte migration and apoptosis.
Journal of lipid research 2010;51(7):1962-70.
2010: Elizabeth J Tarling; Dragana D Bojanic; Rajendra K Tangirala; Xuping Wang; Anita Lovgren-Sandblom; Aldons J Lusis; Ingemar Bjorkhem; Peter A Edwards
Impaired development of atherosclerosis in Abcg1-/- Apoe-/- mice: identification of specific oxysterols that both accumulate in Abcg1-/- Apoe-/- tissues and induce apoptosis.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(6):1174-80.
2010: Peter Gargalovic; Ayça Erbilgin; Omid Kohannim; Joanne Pagnon; Xuping Wang; Lawrence Castellani; Renee LeBoeuf; Martha L Peterson; Brett T Spear; Aldons J Lusis
Quantitative trait locus mapping and identification of Zhx2 as a novel regulator of plasma lipid metabolism.
Circulation. Cardiovascular genetics 2010;3(1):60-7.
2010: Jennifer M P Woo; Zhuofeng Lin; Mohamad Navab; Casey Van Dyck; Yvette Trejo-Lopez; Krystal M T Woo; Hongyun Li; Lawrence W Castellani; Xuping Wang; Noriko Iikuni; Ornella J Rullo; Hui Wu; Antonio La Cava; Alan M Fogelman; Aldons J Lusis; Betty P Tsao
Treatment with apolipoprotein A-1 mimetic peptide reduces lupus-like manifestations in a murine lupus model of accelerated atherosclerosis.
Arthritis research & therapy 2010;12(3):R93.
2010: Michael M Weinstein; Liya Yin; Yiping Tu; Xuping Wang; Xiaohui Wu; Lawrence W Castellani; Rosemary Walzem; Aldons J Lusis; Loren G Fong; Anne P Beigneux; Stephen G Young
Chylomicronemia elicits atherosclerosis in mice--brief report.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(1):20-3.
2009: Susanna S Wang; Lisa J Martin; Eric E Schadt; Haijin Meng; Xuping Wang; Wei Zhao; Leslie Ingram-Drake; Martina Nebohacova; Margarete Mehrabian; Thomas A Drake; Aldons J Lusis
Disruption of the aortic elastic lamina and medial calcification share genetic determinants in mice.
Circulation. Cardiovascular genetics 2009;2(6):573-82.
2009: Zory Shaposhnik; Xuping Wang; Joaquim Trias; Heather Fraser; Aldons J Lusis
The synergistic inhibition of atherogenesis in apoE-/- mice between pravastatin and the sPLA2 inhibitor varespladib (A-002).
Journal of lipid research 2009;50(4):623-9.
2009: Brian J Bennett; Susanna S Wang; Xuping Wang; Xiaohui Wu; Aldons J Lusis
Genetic regulation of atherosclerotic plaque size and morphology in the innominate artery of hyperlipidemic mice.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(3):348-55.
2008: Jesus A Araujo; Berenice Barajas; Michael T Kleinman; Xuping Wang; Brian J Bennett; Ke Wei Gong; Mohamad Navab; Jack Harkema; Constantinos Sioutas; Aldons J Lusis; Andre E Nel
Ambient particulate pollutants in the ultrafine range promote early atherosclerosis and systemic oxidative stress.
Circulation research 2008;102(5):589-96.
2007: Susanna S Wang; Weibin Shi; Xuping Wang; Leandra Velky; Sarah Greenlee; Min T Wang; Thomas A Drake; Aldons J Lusis
Mapping, genetic isolation, and characterization of genetic loci that determine resistance to atherosclerosis in C3H mice.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(12):2671-6.
2007: Michelle N Bradley; Cynthia Hong; Mingyi Chen; Sean B Joseph; DAMIEN WILPITZ; Xuping Wang; Aldons J Lusis; Allan Collins; Willa A Hseuh; Jon L Collins; Rajendra K Tangirala; Peter Tontonoz
Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE.
The Journal of clinical investigation 2007;117(8):2337-46.
2007: Luz D Orozco; Matthias H Kapturczak; Berenice Barajas; Xuping Wang; Michael M Weinstein; Jack Wong; Jessy Deshane; Subhashini Bolisetty; Zory Shaposhnik; Diana M Shih; Anupam Agarwal; Aldons J Lusis; Jesus A Araujo
Heme oxygenase-1 expression in macrophages plays a beneficial role in atherosclerosis.
Circulation research 2007;100(12):1703-11.
2007: Xuebing Feng; Hongyun Li; Alexis A Rumbin; Xuping Wang; Antonio La Cava; Katherine Brechtelsbauer; Lawrence W Castellani; Joseph L Witztum; Aldons J Lusis; Betty P Tsao
ApoE-/-Fas-/- C57BL/6 mice: a novel murine model simultaneously exhibits lupus nephritis, atherosclerosis, and osteopenia.
Journal of lipid research 2007;48(4):794-805.
2007: Zory Shaposhnik; Xuping Wang; Michael Weinstein; Brian J Bennett; Aldons J Lusis
Granulocyte macrophage colony-stimulating factor regulates dendritic cell content of atherosclerotic lesions.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(3):621-7.
2006: Yanqiao Zhang; Xuping Wang; Charisse Vales; Florence Ying Lee; Hans Lee; Aldons J Lusis; Peter A Edwards
FXR deficiency causes reduced atherosclerosis in Ldlr-/- mice.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(10):2316-21.
2006: Daria Estrada-Smith; Alan R Collins; Xuping Wang; Craig Crockett; Lawrence W Castellani; Aldons J Lusis; Richard C Davis
Impact of chromosome 2 obesity loci on cardiovascular complications of insulin resistance in LDL receptor-deficient C57BL/6 mice.
Diabetes 2006;55(8):2265-71.
2006: Lawrence W Castellani; James J Chang; Xuping Wang; Aldons J Lusis; Wanda F Reynolds
Transgenic mice express human MPO -463G/A alleles at atherosclerotic lesions, developing hyperlipidemia and obesity in -463G males.
Journal of lipid research 2006;47(7):1366-77.
2006: Anatole Ghazalpour; Xuping Wang; Aldons J Lusis; Margarete Mehrabian
Complex inheritance of the 5-lipoxygenase locus influencing atherosclerosis in mice.
Genetics 2006;173(2):943-51.
2004: Xuping Wang; Peter Gargalovic; Jack Wong; Jennifer L Gu; Xiaohui Wu; Hongxiu Qi; Pingzi Wen; Li Xi; Bing Tan; Rocky Gogliotti; Lawrence W Castellani; Aurobindo Chatterjee; Aldons J Lusis
Hyplip2, a new gene for combined hyperlipidemia and increased atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(10):1928-34.
2003: Veronica V Colinayo; Jian-Hua Qiao; Xuping Wang; Kelly L Krass; Eric E Schadt; Aldons J Lusis; Thomas A Drake
Genetic loci for diet-induced atherosclerotic lesions and plasma lipids in mice.
Mammalian genome : official journal of the International Mammalian Genome Society 2003;14(7):464-71.
2002: Sean B Joseph; Elaine McKilligin; Liming Pei; Michael A Watson; Alan R Collins; Bryan A Laffitte; Mingyi Chen; Grace Noh; Joanne Goodman; Graham N Hagger; Jonathan Tran; Timothy K Tippin; Xuping Wang; Aldons J Lusis; Willa A Hsueh; Ronald E Law; Jon L Collins; Timothy M Willson; Peter Tontonoz
Synthetic LXR ligand inhibits the development of atherosclerosis in mice.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(11):7604-9.
2001: Margarete Mehrabian; Jack Wong; Xuping Wang; Z Jiang; Weibin Shi; Alan M Fogelman; Aldons J Lusis
Genetic locus in mice that blocks development of atherosclerosis despite extreme hyperlipidemia.
Circulation research 2001;89(2):125-30.
2001: Marie-Luise Brennan; Martin M Anderson; D M Shih; XD Qu; Xuping Wang; A C Mehta; L L Lim; W Shi; Stanley L Hazen; J S Jacob; Jan R Crowley; Jay W Heinecke; Aldons J Lusis
Increased atherosclerosis in myeloperoxidase-deficient mice.
The Journal of clinical investigation 2001;107(4):419-30.
2000: Weibin Shi; Xuping Wang; Nicholas J Wang; william mcbride; Aldons J Lusis
Effect of macrophage-derived apolipoprotein E on established atherosclerosis in apolipoprotein E-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(10):2261-6.
2000: Weibin Shi; Nicholas J Wang; Diana M Shih; V Z Sun; Xuping Wang; Aldons J Lusis
Determinants of atherosclerosis susceptibility in the C3H and C57BL/6 mouse model: evidence for involvement of endothelial cells but not blood cells or cholesterol metabolism.
Circulation research 2000;86(10):1078-84.
2000: A Mouzeyan; J Choi; Hooman Allayee; Xuping Wang; Janet S Sinsheimer; Jack Phan; Lawrence W Castellani; Karen Reue; Aldons J Lusis; Richard C Davis
A locus conferring resistance to diet-induced hypercholesterolemia and atherosclerosis on mouse chromosome 2.
Journal of lipid research 2000;41(4):573-82.