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Xukun Wang

Research Profile

Living Beings

Chemicals & Drugs

Procedures

In Situ Hybridization

Concepts & Ideas

Anatomy

Genes & Molecular Sequences

Amino Acid Sequences

Physiology

Gene Expression Regulation, Developmental

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Publications

TOP 3
Haishan Wang; Xukun Wang; Jeanette M Wood; Xiaofeng Wu; Pauline Yeo; Niefang Yu; Zahid Bonday; Joyce Wei Wei Chang; Dizhong Chen; Weiping Deng; Brian W Dymock; Lijuan Fang; Kee Chuan Goh; Kay Lin Goh; Siok Kun Goh; Changyong Hu; Ethirajulu Kantharaj; Hwee Hoon Khng; Mui Ling Khoo; Ken Chi Lik Lee; Xin Liu; Ting Lu; Pek Ling Lye; Melvin Chi Yeh Ng; Anders Poulsen; Kanda Sangthongpitag; Eric T Sun
Discovery of (2E)-3-{2-butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl}-N-hydroxyacrylamide (SB939), an orally active histone deacetylase inhibitor with a superior preclinical profile.
Xukun Wang; G Baskaran; Z Q Liu; J Huijben; J B Yi; A Annadi; A Roy Barman; A Rusydi; S Dhar; Yuan Ping Feng; J Ding; H Hilgenkamp; T Venkatesan
Electronic phase separation at the LaAlO₃/SrTiO₃ interface.
Haishan Wang; Ze-Yi Lim; Yan Zhou; Melvin Ng; Ting Lu; Ken Lee; Kanda Sangthongpitag; Kee Chuan Goh; Xukun Wang; Xiaofeng Wu; Hwee Hoon Khng; Siok Kun Goh; Wai Chung Ong; Zahid Bonday; Eric T Sun
Acylurea connected straight chain hydroxamates as novel histone deacetylase inhibitors: Synthesis, SAR, and in vivo antitumor activity.

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All Publications

2011: Haishan Wang; Xukun Wang; Jeanette M Wood; Xiaofeng Wu; Pauline Yeo; Niefang Yu; Zahid Bonday; Joyce Wei Wei Chang; Dizhong Chen; Weiping Deng; Brian W Dymock; Lijuan Fang; Kee Chuan Goh; Kay Lin Goh; Siok Kun Goh; Changyong Hu; Ethirajulu Kantharaj; Hwee Hoon Khng; Mui Ling Khoo; Ken Chi Lik Lee; Xin Liu; Ting Lu; Pek Ling Lye; Melvin Chi Yeh Ng; Anders Poulsen; Kanda Sangthongpitag; Eric T Sun
Discovery of (2E)-3-{2-butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl}-N-hydroxyacrylamide (SB939), an orally active histone deacetylase inhibitor with a superior preclinical profile.
Journal of medicinal chemistry 2011;54(13):4694-720.
2011: Xukun Wang; G Baskaran; Z Q Liu; J Huijben; J B Yi; A Annadi; A Roy Barman; A Rusydi; S Dhar; Yuan Ping Feng; J Ding; H Hilgenkamp; T Venkatesan
Electronic phase separation at the LaAlO₃/SrTiO₃ interface.
Nature communications 2011;2():188.
2010: Haishan Wang; Ze-Yi Lim; Yan Zhou; Melvin Ng; Ting Lu; Ken Lee; Kanda Sangthongpitag; Kee Chuan Goh; Xukun Wang; Xiaofeng Wu; Hwee Hoon Khng; Siok Kun Goh; Wai Chung Ong; Zahid Bonday; Eric T Sun
Acylurea connected straight chain hydroxamates as novel histone deacetylase inhibitors: Synthesis, SAR, and in vivo antitumor activity.
Bioorganic & medicinal chemistry letters 2010;20(11):3314-21.
2009: Haishan Wang; Niefang Yu; Hongyan Song; Dizhong Chen; Yong Zou; Weiping Deng; Pek Ling Lye; Joyce Chang; Melvin Ng; Eric T Sun; Kanda Sangthongpitag; Xukun Wang; Xiaofeng Wu; Hwee Hoon Khng; Lijuan Fang; Siok Kun Goh; Wai Chung Ong; Zahid Bonday; Walter Stünkel; Anders Poulsen; Michael Entzeroth
N-Hydroxy-1,2-disubstituted-1H-benzimidazol-5-yl acrylamides as novel histone deacetylase inhibitors: design, synthesis, SAR studies, and in vivo antitumor activity.
Bioorganic & medicinal chemistry letters 2009;19(5):1403-8.
2007: Walter Stünkel; Bee Keow Peh; Yong Cheng Tan; Vasantha Nayagam; Xukun Wang; Manuel Salto-Tellez; BinHui Ni; Michael Entzeroth; Jeanette Wood
Function of the SIRT1 protein deacetylase in cancer.
Biotechnology journal 2007;2(11):1360-8.
2006: Vasantha Nayagam; Xukun Wang; Yong Cheng Tan; Anders Poulsen; Kee Chuan Goh; Tony Ng; Haishan Wang; Hong Yan Song; Binhui Ni; Michael Entzeroth; Walter Stünkel
SIRT1 modulating compounds from high-throughput screening as anti-inflammatory and insulin-sensitizing agents.
Journal of biomolecular screening 2006;11(8):959-67.
2003: Xukun Wang; Alexander Emelyanov; Vladimir Korzh; Zhiyuan Gong
Zebrafish atonal homologue zath3 is expressed during neurogenesis in embryonic development.
Developmental dynamics : an official publication of the American Association of Anatomists 2003;227(4):587-92.
2003: Bensheng Ju; Shang-Wei Chong; Jiangyan He; Xukun Wang; Yanfei Xu; Haiyan Wan; Yan Tong; Tie Yan; Vladimir Korzh; Zhiyuan Gong
Recapitulation of fast skeletal muscle development in zebrafish by transgenic expression of GFP under the mylz2 promoter.
Developmental dynamics : an official publication of the American Association of Anatomists 2003;227(1):14-26.
2002: Xukun Wang; Vladimir Korzh; Zhiyuan Gong
The functional specificity of NeuroD is defined by a single amino acid residue (N11) in the basic domain.
FEBS letters 2002;520(1-3):139-44.
2002: Zhiyuan Gong; Bensheng Ju; Xukun Wang; Jiangyan He; Haiyan Wan; Putter Mudumana Sudha; Tie Yan
Green fluorescent protein expression in germ-line transmitted transgenic zebrafish under a stratified epithelial promoter from keratin8.
Developmental dynamics : an official publication of the American Association of Anatomists 2002;223(2):204-15.
2001: Xukun Wang; L T Chu; Jiangyan He; Alexander Emelyanov; Vladimir Korzh; Zhiyuan Gong
A novel zebrafish bHLH gene, neurogenin3, is expressed in the hypothalamus.
Gene 2001;275(1):47-55.
2001: Xukun Wang; Alexander Emelyanov; Inna Sleptsova-Friedrich; Vladimir Korzh; Zhiyuan Gong
Expression of two novel zebrafish iroquois homologues (ziro1 and ziro5) during early development of axial structures and central nervous system.
Mechanisms of development 2001;105(1-2):191-5.
2000: Yanfei Xu; Jiangyan He; Xukun Wang; Tit Meng Lim; Zhiyuan Gong
Asynchronous activation of 10 muscle-specific protein (MSP) genes during zebrafish somitogenesis.
Developmental dynamics : an official publication of the American Association of Anatomists 2000;219(2):201-15.
1999: Y Zhang; Soek Ying Neo; Xukun Wang; J Han; SC Lin
Axin forms a complex with MEKK1 and activates c-Jun NH(2)-terminal kinase/stress-activated protein kinase through domains distinct from Wnt signaling.
The Journal of biological chemistry 1999;274(49):35247-54.