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Antony Braithwaite

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Annette Lasham; Cristin G Print; Adele G Woolley; Sandra E Dunn; Antony W Braithwaite
YB-1: oncoprotein, prognostic marker and therapeutic target?
Annette Lasham; Reena Mehta; Lance D Miller; Rachna Patel; Cristin G Print; Glen Reid; Weini Samuel; Andrew N Shelling; J Lewis Stern; Adele G Woolley; Michael A Black; Helen Cao; Antony W Braithwaite
YB-1, the E2F pathway, and regulation of tumor cell growth.
Tania L Slatter; Noelyn Hung; Hamish Campbell; Carina Rubio; Reena Mehta; Prudence Renshaw; Gail Williams; Michelle Wilson; Afra Engelmann; AR Jeffs; Janice A Royds; Margaret A Baird; Antony W Braithwaite
Hyperproliferation, cancer, and inflammation in mice expressing a Δ133p53-like isoform.

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All Publications

2013: Annette Lasham; Cristin G Print; Adele G Woolley; Sandra E Dunn; Antony W Braithwaite
YB-1: oncoprotein, prognostic marker and therapeutic target?
The Biochemical journal 2013;449(1):11-23.
2012: Annette Lasham; Reena Mehta; Lance D Miller; Rachna Patel; Cristin G Print; Glen Reid; Weini Samuel; Andrew N Shelling; J Lewis Stern; Adele G Woolley; Michael A Black; Helen Cao; Antony W Braithwaite
YB-1, the E2F pathway, and regulation of tumor cell growth.
Journal of the National Cancer Institute 2012;104(2):133-46.
2011: Tania L Slatter; Noelyn Hung; Hamish Campbell; Carina Rubio; Reena Mehta; Prudence Renshaw; Gail Williams; Michelle Wilson; Afra Engelmann; AR Jeffs; Janice A Royds; Margaret A Baird; Antony W Braithwaite
Hyperproliferation, cancer, and inflammation in mice expressing a Δ133p53-like isoform.
Blood 2011;117(19):5166-77.
2011: Janice A Royds; Alisha Shaw; Anna K Wiles; Antonio Ahn; Shafagh Al Nadaf; Bruce C Baguley; Sara Bowie; Antony W Braithwaite; Yu-Jen Chen; Noelyn A Hung; Frederic Lam; Martin R MacFarlane; Tania L Slatter
The CDKN2A G500 allele is more frequent in GBM patients with no defined telomere maintenance mechanism tumors and is associated with poorer survival.
PloS one 2011;6(10):e26737.
2011: Adele G Woolley; Han-Seung Yoon; Michael Algie; Boon-Huat Bay; Scott B Cohen; Peter Hains; Rhodri Harfoot; Noelyn A Hung; Lily Huschtscha; Annette Lasham; David Perez; Phillip J Robinson; Janice A Royds; Weini Samuel; Puay Hoon Tan; Valentina A Valova; Anna Wiles; Antony W Braithwaite
Prognostic association of YB-1 expression in breast cancers: a matter of antibody.
PloS one 2011;6(6):e20603.
2010: T L Slatter; P Ganesan; C Holzhauer; R Mehta; C Rubio; G Williams; M Wilson; Janice A Royds; M A Baird; Antony W Braithwaite
p53-mediated apoptosis prevents the accumulation of progenitor B cells and B-cell tumors.
Cell death and differentiation 2010;17(3):540-50.
2009: Merilyn H Hibma; Nicola C Real; Anna Wiles; Deirdre Dobson-Le; Brett R Dix; David Wynford-Thomas; Antony W Braithwaite; Janice A Royds
Increased apoptosis and reduced replication efficiency of the E3 region-modified dl309 adenovirus in cancer cells.
Virus research 2009;145(1):112-20.
2009: Robert J Hancox; Richie Poulton; David Welch; Nelly Olova; Christene R McLachlan; Justina M Greene; Malcolm R Sears; Avshalom Caspi; Terrie E Moffitt; Stephen P Robertson; Antony W Braithwaite
Accelerated decline in lung function in cigarette smokers is associated with TP53/MDM2 polymorphisms.
Human genetics 2009;126(4):559-65.
2008: Yu-Jen Chen; Hamish G Campbell; Anna K Wiles; Michael Eccles; Roger R Reddel; Antony W Braithwaite; Janice A Royds
PAX8 regulates telomerase reverse transcriptase and telomerase RNA component in glioma.
Cancer research 2008;68(14):5724-32.
2008: Bostjan Humar; LA McNoe; Anita Dunbier; Rosemary Heathcott; Antony W Braithwaite; Anthony E Reeve
Heterogeneous gene expression changes in colorectal cancer cells share the WNT pathway in response to growth suppression by APHS-mediated COX-2 inhibition.
Biologics : targets & therapy 2008;2(2):329-37.
2006: Yu-Jen Chen; vicky hakin-smith; Mario Teo; George E Xinarianos; David A Jellinek; Thomas Carroll; David McDowell; Martin R MacFarlane; Ronald Boet; Bruce C Baguley; Antony W Braithwaite; Roger R Reddel; Janice A Royds
Association of mutant TP53 with alternative lengthening of telomeres and favorable prognosis in glioma.
Cancer research 2006;66(13):6473-6.
2006: Antony W Braithwaite; G Del Sal; X Lu
Some p53-binding proteins that can function as arbiters of life and death.
Cell death and differentiation 2006;13(6):984-93.
2006: Janice A Royds; Merilyn Hibma; Brett R Dix; Lynne Hananeia; I Alasdair Russell; A Wiles; D Wynford-Thomas; Antony W Braithwaite
p53 promotes adenoviral replication and increases late viral gene expression.
Oncogene 2006;25(10):1509-20.
2005: Craig Homer; Deborah A Knight; Lynne Hananeia; Philip W Sheard; Joanna Risk; Annette Lasham; Janice A Royds; Antony W Braithwaite
Y-box factor YB1 controls p53 apoptotic function.
Oncogene 2005;24(56):8314-25.
2005: Antony W Braithwaite; Janice A Royds; Paul Jackson
The p53 story: layers of complexity.
Carcinogenesis 2005;26(7):1161-9.
2005: Shu-Jie He; Graham Stevens; Antony W Braithwaite; Michael Eccles
Transfection of melanoma cells with antisense PAX3 oligonucleotides additively complements cisplatin-induced cytotoxicity.
Molecular cancer therapeutics 2005;4(6):996-1003.
2004: I Alasdair Russell; Janice A Royds; Antony W Braithwaite
Exploitation of cell cycle and cell death controls by adenoviruses: the road to a productive infection.
Progress in molecular and subcellular biology 2004;36():207-43.
2003: Richard J Hall; Marilyn E Merriman; Rachel A Green; Valerie H Markham; Deborah J Smyth; Joanne M Heward; Claire E Jennings; Antony W Braithwaite; Tim Cundy; Brian A Darlow; Peter J Gow; Andrew A Harrison; John Highton; Penny J Hunt; Patrick Manning; Violetta Pokorny; Russell S Scott; Barry J Taylor; Jinny A Willis; Sue Yeoman; Lachy McLean; S C L Gough; Simon H S Pearce; Tony R Merriman
The deleted in colorectal carcinoma (DCC) gene 201 R --> G polymorphism: no evidence for genetic association with autoimmune disease.
European journal of human genetics : EJHG 2003;11(11):840-4.
2003: Annette Lasham; Stephanie Moloney; Tracy Hale; Craig Homer; You Fang Zhang; J Greg Murison; Antony W Braithwaite; James Watson
The Y-box-binding protein, YB1, is a potential negative regulator of the p53 tumor suppressor.
The Journal of biological chemistry 2003;278(37):35516-23.
2003: Sara J Edwards; Lynne Hananeia; Michael Eccles; You Fang Zhang; Antony W Braithwaite
The proline-rich region of mouse p53 influences transactivation and apoptosis but is largely dispensable for these functions.
Oncogene 2003;22(29):4517-23.
2003: You Fang Zhang; Craig Homer; Sara J Edwards; Lynne Hananeia; Annette Lasham; Janice A Royds; Philip W Sheard; Antony W Braithwaite
Nuclear localization of Y-box factor YB1 requires wild-type p53.
Oncogene 2003;22(18):2782-94.
2002: Sara J Edwards; Brett R Dix; Colleen J Myers; Deirdre Dobson-Le; Lily Huschtscha; Merilyn Hibma; Janice A Royds; Antony W Braithwaite
Evidence that replication of the antitumor adenovirus ONYX-015 is not controlled by the p53 and p14(ARF) tumor suppressor genes.
Journal of virology 2002;76(24):12483-90.
2001: Antony W Braithwaite; I Alasdair Russell
Induction of cell death by adenoviruses.
Apoptosis : an international journal on programmed cell death 2001;6(5):359-70.
2001: WM Thomson; Sara J Edwards; D P Dobson-Le; Geoffrey R Tompkins; Richie Poulton; D A Knight; Antony W Braithwaite
IL-1 genotype and adult periodontitis among young New Zealanders.
Journal of dental research 2001;80(8):1700-3.
2001: M Hibma; Antony W Braithwaite
Viruses to the rescue: p53-based therapies in the fight against cancer.
The New Zealand medical journal 2001;114(1133):266-9.
2001: Brett R Dix; Sara J Edwards; Antony W Braithwaite
Does the antitumor adenovirus ONYX-015/dl1520 selectively target cells defective in the p53 pathway?
Journal of virology 2001;75(12):5443-7.
2000: Tracy Hale; C Myers; R Maitra; T Kolzau; M Nishizawa; Antony W Braithwaite
Maf transcriptionally activates the mouse p53 promoter and causes a p53-dependent cell death.
The Journal of biological chemistry 2000;275(24):17991-9.
2000: Brett R Dix; SJ O'Carroll; Colleen J Myers; Sara J Edwards; Antony W Braithwaite
Efficient induction of cell death by adenoviruses requires binding of E1B55k and p53.
Cancer research 2000;60(10):2666-72.
2000: SJ O'Carroll; AR Hall; Colleen J Myers; Antony W Braithwaite; Brett R Dix
Quantifying adenoviral titers by spectrophotometry.
BioTechniques 2000;28(3):408-10, 412.
1999: T Kolzau; R S Hansen; D Zahra; Roger R Reddel; Antony W Braithwaite
Inhibition of SV40 large T antigen induced apoptosis by small T antigen.
Oncogene 1999;18(40):5598-603.
1999: Tracy Hale; Antony W Braithwaite
The adenovirus oncoprotein E1a stimulates binding of transcription factor ETF to transcriptionally activate the p53 gene.
The Journal of biological chemistry 1999;274(34):23777-86.
1998: AR Hall; Brett R Dix; SJ O'Carroll; Antony W Braithwaite
p53-dependent cell death/apoptosis is required for a productive adenovirus infection.
Nature medicine 1998;4(9):1068-72.
1997: P J Ridgway; AR Hall; Colleen J Myers; Antony W Braithwaite
p53/E1b58kDa complex regulates adenovirus replication.
Virology 1997;237(2):404-13.
1997: Antony W Braithwaite; Richie Poulton
Relevance in health research funding: reality or myth?
The New Zealand medical journal 1997;110(1052):361-2.
1997: A R Hall; Antony W Braithwaite
p53: from clinical significance to significance in the clinic?
The New Zealand medical journal 1997;110(1052):347-8.
1996: L Sedger; Ian A Ramshaw; A Condie; J Medveczky; Antony W Braithwaite; J Ruby
Vaccinia virus replication is independent of cellular HSP72 expression which is induced during virus infection.
Virology 1996;225(2):423-7.
1996: R S Hansen; Antony W Braithwaite
The growth-inhibitory function of p53 is separable from transactivation, apoptosis and suppression of transformation by E1a and Ras.
Oncogene 1996;13(5):995-1007.
1995: R Hansen; R Reddel; Antony W Braithwaite
The transforming oncoproteins determine the mechanism by which p53 suppresses cell transformation: pRb-mediated growth arrest or apoptosis.
Oncogene 1995;11(12):2535-45.
1995: K Perrem; J Rayner; T Voss; H Sturzbecher; P Jackson; Antony W Braithwaite
p53 represses SV40 transcription by preventing formation of transcription complexes.
Oncogene 1995;11(7):1299-307.
1995: T K Hale; Antony W Braithwaite
Identification of an upstream region of the mouse p53 promoter critical for transcriptional expression.
Nucleic acids research 1995;23(4):663-9.
1995: P Jackson; M Shield; J Buskin; S Hawkes; M Reed; K Perrem; S D Hauschka; Antony W Braithwaite
p53-dependent activation of the mouse MCK gene promoter: identification of a novel p53-responsive sequence and evidence for cooperation between distinct p53 binding sites.
Gene expression 1995;5(1):19-33.
1994: P J Ridgway; thierry soussi; Antony W Braithwaite
Functional characterization of Xenopus laevis p53: evidence of temperature-sensitive transactivation but not of repression.
Journal of virology 1994;68(11):7178-87.
1994: P Jackson; P Ridgway; J Rayner; J Noble; Antony W Braithwaite
Transcriptional regulation of the PCNA promoter by p53.
Biochemical and biophysical research communications 1994;203(1):133-40.
1994: X Zhang; A J Bellett; R T Hla; T Voss; Arno Müllbacher; Antony W Braithwaite
Down-regulation of human adenovirus E1a by E3 gene products: evidence for translational control of E1a by E3 14.5K and/or E3 10.4K products.
The Journal of general virology 1994;75 ( Pt 8)():1943-51.
1993: P J Ridgway; T K Hale; Antony W Braithwaite
p53 confers a selective advantage on transfected HeLa cells.
Oncogene 1993;8(4):1069-74.
1993: P Jackson; E Bos; Antony W Braithwaite
Wild-type mouse p53 down-regulates transcription from different virus enhancer/promoters.
Oncogene 1993;8(3):589-97.
1992: X Zhang; Arno Müllbacher; Antony W Braithwaite
Down-regulation of E1a expression by E3 gene products in group C adenoviruses.
Immunology and cell biology 1992;70 ( Pt 1)():65-71.
1991: Antony W Braithwaite; G E Blair; C C Nelson; J McGovern; A J Bellett
Adenovirus E1b-58 kD antigen binds to p53 during infection of rodent cells: evidence for an N-terminal binding site on p53.
Oncogene 1991;6(5):781-7.
1991: Antony W Braithwaite; C C Nelson; A J Bellett
E1a revisited: the case for multiple cooperative trans-activation domains.
The New biologist 1991;3(1):18-26.
1991: X L Zhang; A J Bellett; R T Hla; Antony W Braithwaite; Arno Müllbacher
Adenovirus type 5 E3 gene products interfere with the expression of the cytolytic T cell immunodominant E1a antigen.
Virology 1991;180(1):199-206.
1990: C C Nelson; Antony W Braithwaite; M Silvestro; A J Bellett
E1a-dependent expression of adenovirus genes in OTF963 embryonal carcinoma cells: role of E1a-induced differentiation.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(20):8041-5.
1990: C C Nelson; Antony W Braithwaite; M Silvestro; A J Bellett
Defective expression of adenovirus genes during early infection of undifferentiated OTF963 embryonal carcinoma cells.
Journal of virology 1990;64(9):4329-37.
1990: Antony W Braithwaite; C Nelson; A Skulimowski; J McGovern; D Pigott; J Jenkins
Transactivation of the p53 oncogene by E1a gene products.
Virology 1990;177(2):595-605.
1990: Paul Waring; M Egan; Antony W Braithwaite; A Mullbacher; A Sjaarda
Apoptosis induced in macrophages and T blasts by the mycotoxin sporidesmin and protection by Zn2+ salts.
International journal of immunopharmacology 1990;12(4):445-57.
1988: R D Eichner; Paul Waring; A M Geue; Antony W Braithwaite; Arno Müllbacher
Gliotoxin causes oxidative damage to plasmid and cellular DNA.
The Journal of biological chemistry 1988;263(8):3772-7.
1987: Arno Müllbacher; D Hume; Antony W Braithwaite; Paul Waring; R D Eichner
Selective resistance of bone marrow-derived hemopoietic progenitor cells to gliotoxin.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(11):3822-5.
1987: Antony W Braithwaite; R D Eichner; Paul Waring; Arno Müllbacher
The immunomodulating agent gliotoxin causes genomic DNA fragmentation.
Molecular immunology 1987;24(1):47-55.
1985: A J Bellett; P Li; E T David; E J Mackey; Antony W Braithwaite; J R Cutt
Control functions of adenovirus transformation region E1A gene products in rat and human cells.
Molecular and cellular biology 1985;5(8):1933-9.
1983: Antony W Braithwaite; B F Cheetham; P Li; C R Parish; L K Waldron-Stevens; A J Bellett
Adenovirus-induced alterations of the cell growth cycle: a requirement for expression of E1A but not of E1B.
Journal of virology 1983;45(1):192-9.
1982: J D Murray; Antony W Braithwaite; I W Taylor; A J Bellett
Adenovirus-induced alterations of the cell growth cycle: effects of mutations in early regions E2A and E2B.
Journal of virology 1982;44(3):1072-5.
1982: J D Murray; A J Bellett; Antony W Braithwaite; L K Waldron; I W Taylor
Altered cell cycle progression and aberrant mitosis in adenovirus-infected rodent cells.
Journal of cellular physiology 1982;111(1):89-96.
1982: A J Bellett; L K Waldron-Stevens; Antony W Braithwaite; B F Cheetham
Spermine and aminoguanidine protect cells from chromosome aberrations induced by adenovirus during the G2 phase of the cell cycle.
Chromosoma 1982;84(4):571-83.
1981: Antony W Braithwaite; J D Murray; A J Bellett
Alterations to controls of cellular DNA synthesis by adenovirus infection.
Journal of virology 1981;39(2):331-40.