Cord Brakebusch

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Living Beings

Chemicals & Drugs

Physiology

Anatomy

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Karlsson R; Pedersen E D; Wang Z; Brakebusch Cord
Rho GTPase function in tumorigenesis.
Kesavan Gokul; Sand Fredrik Wolfhagen; Greiner Thomas Uwe; Johansson Jenny Kristina; Kobberup Sune; Wu Xunwei; Brakebusch Cord; Semb Henrik
Cdc42-mediated tubulogenesis controls cell specification.
Haditsch Ursula; Leone Dino P; Farinelli Mélissa; Chrostek-Grashoff Anna; Brakebusch Cord; Mansuy Isabelle M; McConnell Susan K; Palmer Theo D
A central role for the small GTPase Rac1 in hippocampal plasticity and spatial learning and memory.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Cord Brakebusch (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Karlsson R; Pedersen E D; Wang Z; Brakebusch Cord
Rho GTPase function in tumorigenesis.
Biochimica et biophysica acta 2009;1796(2):91-8.
2009: Kesavan Gokul; Sand Fredrik Wolfhagen; Greiner Thomas Uwe; Johansson Jenny Kristina; Kobberup Sune; Wu Xunwei; Brakebusch Cord; Semb Henrik
Cdc42-mediated tubulogenesis controls cell specification.
Cell 2009;139(4):791-801.
2009: Haditsch Ursula; Leone Dino P; Farinelli Mélissa; Chrostek-Grashoff Anna; Brakebusch Cord; Mansuy Isabelle M; McConnell Susan K; Palmer Theo D
A central role for the small GTPase Rac1 in hippocampal plasticity and spatial learning and memory.
Molecular and cellular neurosciences 2009;41(4):409-19.
2009: Vasyutina Elena; Martarelli Benedetta; Brakebusch Cord; Wende Hagen; Birchmeier Carmen
The small G-proteins Rac1 and Cdc42 are essential for myoblast fusion in the mouse.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(22):8935-40.
2009: Lämmermann Tim; Renkawitz Jörg; Wu Xunwei; Hirsch Karin; Brakebusch Cord; Sixt Michael
Cdc42-dependent leading edge coordination is essential for interstitial dendritic cell migration.
Blood 2009;113(23):5703-10.
2009: Du Dan; Pedersen Esben; Wang Zhipeng; Karlsson Richard; Chen Zhengjun; Wu Xunwei; Brakebusch Cord
Cdc42 is crucial for the maturation of primordial cell junctions in keratinocytes independent of Rac1.
Experimental cell research 2009;315(8):1480-9.
2009: Fuchs Sebastian; Herzog Dominik; Sumara Grzegorz; Büchmann-Møller Stine; Civenni Gianluca; Wu Xunwei; Chrostek-Grashoff Anna; Suter Ueli; Ricci Romeo; Relvas João B; Brakebusch Cord; Sommer Lukas
Stage-specific control of neural crest stem cell proliferation by the small rho GTPases Cdc42 and Rac1.
Cell stem cell 2009;4(3):236-47.
2009: Pleines Irina; Elvers Margitta; Strehl Amrei; Pozgajova Miroslava; Varga-Szabo David; May Frauke; Chrostek-Grashoff Anna; Brakebusch Cord; Nieswandt Bernhard
Rac1 is essential for phospholipase C-gamma2 activation in platelets.
Pflügers Archiv : European journal of physiology 2009;457(5):1173-85.
2009: Bauer Martina; Brakebusch Cord; Coisne Caroline; Sixt Michael; Wekerle Hartmut; Engelhardt Britta; Fässler Reinhard
Beta1 integrins differentially control extravasation of inflammatory cell subsets into the CNS during autoimmunity.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(6):1920-5.
2009: Yuan Haixin; Zhang Hong; Wu Xunwei; Zhang Zhe; Du Dan; Zhou Wenchao; Zhou Shuhua; Brakebusch Cord; Chen Zhengjun
Hepatocyte-specific deletion of Cdc42 results in delayed liver regeneration after partial hepatectomy in mice.
Hepatology (Baltimore, Md.) 2009;49(1):240-9.
2009: Piwko-Czuchra Aleksandra; Koegel Heidi; Meyer Hannelore; Bauer Martina; Werner Sabine; Brakebusch Cord; Fässler Reinhard
Beta1 integrin-mediated adhesion signalling is essential for epidermal progenitor cell expansion.
PloS one 2009;4(5):e5488.
2008: van Hengel Jolanda; D'Hooge Petra; Hooghe Bart; Wu Xunwei; Libbrecht Louis; De Vos Rita; Quondamatteo Fabio; Klempt Martina; Brakebusch Cord; van Roy Frans
Continuous cell injury promotes hepatic tumorigenesis in cdc42-deficient mouse liver.
Gastroenterology 2008;134(3):781-92.
2007: Garvalov Boyan K; Flynn Kevin C; Neukirchen Dorothee; Meyn Liane; Teusch Nicole; Wu Xunwei; Brakebusch Cord; Bamburg James R; Bradke Frank
Cdc42 regulates cofilin during the establishment of neuronal polarity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(48):13117-29.
2007: Wu Xunwei; Li Shaohua; Chrostek-Grashoff Anna; Czuchra Aleksandra; Meyer Hannelore; Yurchenco Peter D; Brakebusch Cord
Cdc42 is crucial for the establishment of epithelial polarity during early mammalian development.
Developmental dynamics : an official publication of the American Association of Anatomists 2007;236(10):2767-78.
2007: Bosse Tanja; Ehinger Julia; Czuchra Aleksandra; Benesch Stefanie; Steffen Anika; Wu Xunwei; Schloen Kathrin; Niemann Hartmut H; Scita Giorgio; Stradal Theresia E B; Brakebusch Cord; Rottner Klemens
Cdc42 and phosphoinositide 3-kinase drive Rac-mediated actin polymerization downstream of c-Met in distinct and common pathways.
Molecular and cellular biology 2007;27(19):6615-28.
2007: Benninger Yves; Thurnherr Tina; Pereira Jorge A; Krause Sven; Wu Xunwei; Chrostek-Grashoff Anna; Herzog Dominik; Nave Klaus-Armin; Franklin Robin J M; Meijer Dies; Brakebusch Cord; Suter Ueli; Relvas João B
Essential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development.
The Journal of cell biology 2007;177(6):1051-61.
2007: Tscharntke Michael; Pofahl Ruth; Chrostek-Grashoff Anna; Smyth Neil; Niessen Carien; Niemann Catherin; Hartwig Benedikt; Herzog Volker; Klein Helmut W; Krieg Thomas; Brakebusch Cord; Haase Ingo
Impaired epidermal wound healing in vivo upon inhibition or deletion of Rac1.
Journal of cell science 2007;120(Pt 8):1480-90.
2007: Dorn Tatjana; Kuhn Ursula; Bungartz Gerd; Stiller Sebastian; Bauer Martina; Ellwart Joachim; Peters Thorsten; Scharffetter-Kochanek Karin; Semmrich Monika; Laschinger Melanie; Holzmann Bernhard; Klinkert Wolfgang E F; Straten Per Thor; Køllgaard Tania; Sixt Michael; Brakebusch Cord
RhoH is important for positive thymocyte selection and T-cell receptor signaling.
Blood 2007;109(6):2346-55.
2006: Wu Xunwei; Quondamatteo Fabio; Brakebusch Cord
Cdc42 expression in keratinocytes is required for the maintenance of the basement membrane in skin.
Matrix biology : journal of the International Society for Matrix Biology 2006;25(8):466-74.
2006: Thurnherr Tina; Benninger Yves; Wu Xunwei; Chrostek Anna; Krause Sven M; Nave Klaus-Armin; Franklin Robin J M; Brakebusch Cord; Suter Ueli; Relvas João B
Cdc42 and Rac1 signaling are both required for and act synergistically in the correct formation of myelin sheaths in the CNS.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(40):10110-9.
2006: Czuchra Aleksandra; Meyer Hannelore; Legate Kyle R; Brakebusch Cord; Fässler Reinhard
Genetic analysis of beta1 integrin "activation motifs" in mice.
The Journal of cell biology 2006;174(6):889-99.
2006: Chrostek Anna; Wu Xunwei; Quondamatteo Fabio; Hu Rong; Sanecka Anna; Niemann Catherin; Langbein Lutz; Haase Ingo; Brakebusch Cord
Rac1 is crucial for hair follicle integrity but is not essential for maintenance of the epidermis.
Molecular and cellular biology 2006;26(18):6957-70.
2006: Cappello Silvia; Attardo Alessio; Wu Xunwei; Iwasato Takuji; Itohara Shigeyoshi; Wilsch-Bräuninger Michaela; Eilken Hanna M; Rieger Michael A; Schroeder Timm T; Huttner Wieland B; Brakebusch Cord; Götz Magdalena
The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface.
Nature neuroscience 2006;9(9):1099-107.
2006: Bungartz Gerd; Stiller Sebastian; Bauer Martina; Müller Werner; Schippers Angela; Wagner Norbert; Fässler Reinhard; Brakebusch Cord
Adult murine hematopoiesis can proceed without beta1 and beta7 integrins.
Blood 2006;108(6):1857-64.
2006: Breau Marie A; Pietri Thomas; Eder Olivier; Blanche Martine; Brakebusch Cord; Fässler Reinhardt; Thiery Jean P; Dufour Sylvie
Lack of beta1 integrins in enteric neural crest cells leads to a Hirschsprung-like phenotype.
Development (Cambridge, England) 2006;133(9):1725-34.
2006: Nilsson Stina; Kaniowska Dorota; Brakebusch Cord; Fässler Reinhard; Johansson Staffan
Threonine 788 in integrin subunit beta1 regulates integrin activation.
Experimental cell research 2006;312(6):844-53.
2006: Wu Xunwei; Quondamatteo Fabio; Lefever Tine; Czuchra Aleksandra; Meyer Hannelore; Chrostek Anna; Paus Ralf; Langbein Lutz; Brakebusch Cord
Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin.
Genes & development 2006;20(5):571-85.
2006: Cordes N; Seidler J; Durzok R; Geinitz H; Brakebusch C
beta1-integrin-mediated signaling essentially contributes to cell survival after radiation-induced genotoxic injury.
Oncogene 2006;25(9):1378-90.
2005: Czuchra Aleksandra; Wu Xunwei; Meyer Hannelore; van Hengel Jolanda; Schroeder Timm; Geffers Robert; Rottner Klemens; Brakebusch Cord
Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells.
Molecular biology of the cell 2005;16(10):4473-84.
2005: Brakebusch C; Fässler R
beta 1 integrin function in vivo: adhesion, migration and more.
Cancer metastasis reviews 2005;24(3):403-11.
2005: Seidler Julia; Durzok Rita; Brakebusch Cord; Cordes Nils
Interactions of the integrin subunit beta1A with protein kinase B/Akt, p130Cas and paxillin contribute to regulation of radiation survival.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2005;76(2):129-34.
2005: Leone Dino P; Relvas João B; Campos Lia S; Hemmi Silvio; Brakebusch Cord; Fässler Reinhard; Ffrench-Constant Charles; Suter Ueli
Regulation of neural progenitor proliferation and survival by beta1 integrins.
Journal of cell science 2005;118(Pt 12):2589-99.
2005: Marsal Jan; Brakebusch Cord; Bungartz Gerd; Fässler Reinhard; Agace William W
beta1 integrins are not required for the maintenance of lymphocytes within intestinal epithelia.
European journal of immunology 2005;35(6):1805-11.
2004: Xanthoulea Sofia; Pasparakis Manolis; Kousteni Stavroula; Brakebusch Cord; Wallach David; Bauer Jan; Lassmann Hans; Kollias George
Tumor necrosis factor (TNF) receptor shedding controls thresholds of innate immune activation that balance opposing TNF functions in infectious and inflammatory diseases.
The Journal of experimental medicine 2004;200(3):367-76.
2004: Pietri Thomas; Eder Olivier; Breau Marie Anne; Topilko Piotr; Blanche Martine; Brakebusch Cord; Fässler Reinhard; Thiery Jean-Paul; Dufour Sylvie
Conditional beta1-integrin gene deletion in neural crest cells causes severe developmental alterations of the peripheral nervous system.
Development (Cambridge, England) 2004;131(16):3871-83.
2004: Campos Lia S; Leone Dino P; Relvas Joao B; Brakebusch Cord; Fässler Reinhard; Suter Ueli; ffrench-Constant Charles
Beta1 integrins activate a MAPK signalling pathway in neural stem cells that contributes to their maintenance.
Development (Cambridge, England) 2004;131(14):3433-44.
2003: Grüner Sabine; Prostredna Miroslava; Schulte Valerie; Krieg Thomas; Eckes Beate; Brakebusch Cord; Nieswandt Bernhard
Multiple integrin-ligand interactions synergize in shear-resistant platelet adhesion at sites of arterial injury in vivo.
Blood 2003;102(12):4021-7.
2003: Sitnicka Ewa; Brakebusch Cord; Martensson Inga-Lill; Svensson Marcus; Agace William W; Sigvardsson Mikael; Buza-Vidas Natalija; Bryder David; Cilio Corrado M; Ahlenius Henrik; Maraskovsky Eugene; Peschon Jacques J; Jacobsen Sten Eirik W
Complementary signaling through flt3 and interleukin-7 receptor alpha is indispensable for fetal and adult B cell genesis.
The Journal of experimental medicine 2003;198(10):1495-506.
2003: Aszodi Attila; Hunziker Ernst B; Brakebusch Cord; Fässler Reinhard
Beta1 integrins regulate chondrocyte rotation, G1 progression, and cytokinesis.
Genes & development 2003;17(19):2465-79.
2003: Brakebusch Cord; Fässler Reinhard
The integrin-actin connection, an eternal love affair.
The EMBO journal 2003;22(10):2324-33.
2003: Kuijpers Marijke J E; Schulte Valerie; Bergmeier Wolfgang; Lindhout Theo; Brakebusch Cord; Offermanns Stefan; Fässler Reinhard; Heemskerk Johan W M; Nieswandt Bernhard
Complementary roles of glycoprotein VI and alpha2beta1 integrin in collagen-induced thrombus formation in flowing whole blood ex vivo.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(6):685-7.
2003: Altrock Wilko D; tom Dieck Susanne; Sokolov Maxim; Meyer Alexander C; Sigler Albrecht; Brakebusch Cord; Fässler Reinhard; Richter Karin; Boeckers Tobias M; Potschka Heidrun; Brandt Claudia; Löscher Wolfgang; Grimberg Dörte; Dresbach Thomas; Hempelmann Anne; Hassan Hadir; Balschun Detlef; Frey Julietta U; Brandstätter Johann H; Garner Craig C; Rosenmund Christian; Gundelfinger Eckart D
Functional inactivation of a fraction of excitatory synapses in mice deficient for the active zone protein bassoon.
Neuron 2003;37(5):787-800.
2003: He Zhi-Yong; Brakebusch Cord; Fässler Reinhard; Kreidberg Jordan A; Primakoff Paul; Myles Diana G
None of the integrins known to be present on the mouse egg or to be ADAM receptors are essential for sperm-egg binding and fusion.
Developmental biology 2003;254(2):226-37.
2002: Danen Erik H J; Sonneveld Petra; Brakebusch Cord; Fassler Reinhard; Sonnenberg Arnoud
The fibronectin-binding integrins alpha5beta1 and alphavbeta3 differentially modulate RhoA-GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis.
The Journal of cell biology 2002;159(6):1071-86.
2002: Brakebusch Cord; Seidenbecher Constanze I; Asztely Fredrik; Rauch Uwe; Matthies Henry; Meyer Hannelore; Krug Manfred; Böckers Tobias M; Zhou Xiaohong; Kreutz Michael R; Montag Dirk; Gundelfinger Eckart D; Fässler Reinhard
Brevican-deficient mice display impaired hippocampal CA1 long-term potentiation but show no obvious deficits in learning and memory.
Molecular and cellular biology 2002;22(21):7417-27.
2002: Gustavsson Anna; Armulik Annika; Brakebusch Cord; Fässler Reinhard; Johansson Staffan; Fällman Maria
Role of the beta1-integrin cytoplasmic tail in mediating invasin-promoted internalization of Yersinia.
Journal of cell science 2002;115(Pt 13):2669-78.
2002: Grose Richard; Hutter Caroline; Bloch Wilhelm; Thorey Irmgard; Watt Fiona M; Fässler Reinhard; Brakebusch Cord; Werner Sabine
A crucial role of beta 1 integrins for keratinocyte migration in vitro and during cutaneous wound repair.
Development (Cambridge, England) 2002;129(9):2303-15.
2002: Brakebusch Cord; Bouvard Daniel; Stanchi Fabio; Sakai Takao; Fässler Reinhard
Integrins in invasive growth.
The Journal of clinical investigation 2002;109(8):999-1006.
2002: Brakebusch Cord; Fillatreau Simon; Potocnik Alexandre J; Bungartz Gerd; Wilhelm Patricia; Svensson Marcus; Kearney Phil; Körner Heinrich; Gray David; Fässler Reinhard
Beta1 integrin is not essential for hematopoiesis but is necessary for the T cell-dependent IgM antibody response.
Immunity 2002;16(3):465-77.
2001: Chidgey M; Brakebusch C; Gustafsson E; Cruchley A; Hail C; Kirk S; Merritt A; North A; Tselepis C; Hewitt J; Byrne C; Fassler R; Garrod D
Mice lacking desmocollin 1 show epidermal fragility accompanied by barrier defects and abnormal differentiation.
The Journal of cell biology 2001;155(5):821-32.
2001: Zhou X H; Brakebusch C; Matthies H; Oohashi T; Hirsch E; Moser M; Krug M; Seidenbecher C I; Boeckers T M; Rauch U; Buettner R; Gundelfinger E D; Fässler R
Neurocan is dispensable for brain development.
Molecular and cellular biology 2001;21(17):5970-8.
2001: Bouvard D; Brakebusch C; Gustafsson E; Aszódi A; Bengtsson T; Berna A; Fässler R
Functional consequences of integrin gene mutations in mice.
Circulation research 2001;89(3):211-23.
2001: Bergmeier W; Bouvard D; Eble J A; Mokhtari-Nejad R; Schulte V; Zirngibl H; Brakebusch C; Fässler R; Nieswandt B
Rhodocytin (aggretin) activates platelets lacking alpha(2)beta(1) integrin, glycoprotein VI, and the ligand-binding domain of glycoprotein Ibalpha.
The Journal of biological chemistry 2001;276(27):25121-6.
2001: Nieswandt B; Brakebusch C; Bergmeier W; Schulte V; Bouvard D; Mokhtari-Nejad R; Lindhout T; Heemskerk J W; Zirngibl H; Fässler R
Glycoprotein VI but not alpha2beta1 integrin is essential for platelet interaction with collagen.
The EMBO journal 2001;20(9):2120-30.
2001: Henry M D; Satz J S; Brakebusch C; Costell M; Gustafsson E; Fässler R; Campbell K P
Distinct roles for dystroglycan, beta1 integrin and perlecan in cell surface laminin organization.
Journal of cell science 2001;114(Pt 6):1137-44.
2001: Gustafsson E; Brakebusch C; Hietanen K; Fässler R
Tie-1-directed expression of Cre recombinase in endothelial cells of embryoid bodies and transgenic mice.
Journal of cell science 2001;114(Pt 4):671-6.
2000: Brakebusch C; Grose R; Quondamatteo F; Ramirez A; Jorcano J L; Pirro A; Svensson M; Herken R; Sasaki T; Timpl R; Werner S; Fässler R
Skin and hair follicle integrity is crucially dependent on beta 1 integrin expression on keratinocytes.
The EMBO journal 2000;19(15):3990-4003.
2000: Potocnik A J; Brakebusch C; Fässler R
Fetal and adult hematopoietic stem cells require beta1 integrin function for colonizing fetal liver, spleen, and bone marrow.
Immunity 2000;12(6):653-63.
2000: Dixon J; Brakebusch C; Fässler R; Dixon M J
Increased levels of apoptosis in the prefusion neural folds underlie the craniofacial disorder, Treacher Collins syndrome.
Human molecular genetics 2000;9(10):1473-80.
2000: Iba K; Albrechtsen R; Gilpin B; Fröhlich C; Loechel F; Zolkiewska A; Ishiguro K; Kojima T; Liu W; Langford J K; Sanderson R D; Brakebusch C; Fässler R; Wewer U M
The cysteine-rich domain of human ADAM 12 supports cell adhesion through syndecans and triggers signaling events that lead to beta1 integrin-dependent cell spreading.
The Journal of cell biology 2000;149(5):1143-56.
1999: Gimond C; van Der Flier A; van Delft S; Brakebusch C; Kuikman I; Collard J G; Fässler R; Sonnenberg A
Induction of cell scattering by expression of beta1 integrins in beta1-deficient epithelial cells requires activation of members of the rho family of GTPases and downregulation of cadherin and catenin function.
The Journal of cell biology 1999;147(6):1325-40.
1999: Brakebusch C; Wennerberg K; Krell H W; Weidle U H; Sallmyr A; Johansson S; Fässler R
Beta1 integrin promotes but is not essential for metastasis of ras-myc transformed fibroblasts.
Oncogene 1999;18(26):3852-61.
1999: Brakebusch C; Sures I; Jallal B; Mossie K; Fusco O; Iacobelli S; Ullrich A
Isolation and functional characterization of the human 90K promoter.
Genomics 1999;57(2):268-78.
1999: Talts J F; Brakebusch C; Fässler R
Integrin gene targeting.
Methods in molecular biology (Clifton, N.J.) 1999;129():153-87.
1997: Brakebusch C; Hirsch E; Potocnik A; Fässler R
Genetic analysis of beta1 integrin function: confirmed, new and revised roles for a crucial family of cell adhesion molecules.
Journal of cell science 1997;110 ( Pt 23)():2895-904.
1997: Bloch W; Forsberg E; Lentini S; Brakebusch C; Martin K; Krell H W; Weidle U H; Addicks K; Fässler R
Beta 1 integrin is essential for teratoma growth and angiogenesis.
The Journal of cell biology 1997;139(1):265-78.
1997: Rauch U; Meyer H; Brakebusch C; Seidenbecher C; Gundelfinger E D; Beier D R; Fässler R
Sequence and chromosomal localization of the mouse brevican gene.
Genomics 1997;44(1):15-21.
1997: Brakebusch C; Jallal B; Fusco O; Iacobelli S; Ullrich A
Expression of the 90K immunostimulator gene is controlled by a promoter with unique features.
The Journal of biological chemistry 1997;272(6):3674-82.
1995: Jallal B; Powell J; Zachwieja J; Brakebusch C; Germain L; Jacobs J; Iacobelli S; Ullrich A
Suppression of tumor growth in vivo by local and systemic 90K level increase.
Cancer research 1995;55(15):3223-7.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

Cord Brakebusch

Research Profile (preview)

Living Beings

Chemicals & Drugs

Physiology

Anatomy

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of Cord Brakebusch (preview)

All Publications