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Axel Brakhage
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11
Heinekamp, Thorsten
9
Steidl, Stefan
8
Spröte, Petra
8
Jahn, Bernhard
8
Langfelder, Kim
7
Kniemeyer, Olaf
7
Litzka, Olivier
6
Hynes, Michael
6
Tüncher, André
5
Al-Abdallah, Qusai
5
Weidner, Gerhard
5
Liebmann, Burghard
5
Härtl, Albert
4
Goldman, Gustavo
4
Hortschansky, Peter
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All Publications
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2009: Valiante Vito; Jain Radhika; Heinekamp Thorsten; Brakhage Axel A
The MpkA MAP kinase module regulates cell wall integrity signaling and pyomelanin formation in Aspergillus fumigatus.
Fungal genetics and biology : FG & B 2009;46(12):909-18.
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2009: Brakhage Axel A; Thön Marcel; Spröte Petra; Scharf Daniel H; Al-Abdallah Qusai; Wolke Sandra M; Hortschansky Peter
Aspects on evolution of fungal beta-lactam biosynthesis gene clusters and recruitment of trans-acting factors.
Phytochemistry 2009;70(15-16):1801-11.
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2009: Aimanianda Vishukumar; Bayry Jagadeesh; Bozza Silvia; Kniemeyer Olaf; Perruccio Katia; Elluru Sri Ramulu; Clavaud Cécile; Paris Sophie; Brakhage Axel A; Kaveri Srini V; Romani Luigina; Latgé Jean-Paul
Surface hydrophobin prevents immune recognition of airborne fungal spores.
Nature 2009;460(7259):1117-21.
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2009: Schroeckh Volker; Scherlach Kirstin; Nützmann Hans-Wilhelm; Shelest Ekaterina; Schmidt-Heck Wolfgang; Schuemann Julia; Martin Karin; Hertweck Christian; Brakhage Axel A
Intimate bacterial-fungal interaction triggers biosynthesis of archetypal polyketides in Aspergillus nidulans.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(34):14558-63.
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2009: Rispail Nicolas; Soanes Darren M; Ant Cemile; Czajkowski Robert; Grünler Anke; Huguet Romain; Perez-Nadales Elena; Poli Anna; Sartorel Elodie; Valiante Vito; Yang Meng; Beffa Roland; Brakhage Axel A; Gow Neil A R; Kahmann Regine; Lebrun Marc-Henri; Lenasi Helena; Perez-Martin José; Talbot Nicholas J; Wendland Jürgen; Di Pietro Antonio
Comparative genomics of MAP kinase and calcium-calcineurin signalling components in plant and human pathogenic fungi.
Fungal genetics and biology : FG & B 2009;46(4):287-98.
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2009: Vödisch Martin; Albrecht Daniela; Lessing Franziska; Schmidt André D; Winkler Robert; Guthke Reinhard; Brakhage Axel A; Kniemeyer Olaf
Two-dimensional proteome reference maps for the human pathogenic filamentous fungus Aspergillus fumigatus.
Proteomics 2009;9(5):1407-15.
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2009: Spröte Petra; Brakhage Axel A; Hynes Michael J
Contribution of peroxisomes to penicillin biosynthesis in Aspergillus nidulans.
Eukaryotic cell 2009;8(3):421-3.
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2009: Schmaler-Ripcke Jeannette; Sugareva Venelina; Gebhardt Peter; Winkler Robert; Kniemeyer Olaf; Heinekamp Thorsten; Brakhage Axel A
Production of pyomelanin, a second type of melanin, via the tyrosine degradation pathway in Aspergillus fumigatus.
Applied and environmental microbiology 2009;75(2):493-503.
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2009: Kniemeyer Olaf; Lessing Franziska; Brakhage Axel A
Proteome analysis for pathogenicity and new diagnostic markers for Aspergillus fumigatus.
Medical mycology : official publication of the International Society for Human and Animal Mycology 2009;47 Suppl 1():S248-54.
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2008: Mota Júnior André Oliveira; Malavazi Iran; Soriani Frederico Marianetti; Heinekamp Thorsten; Jacobsen Ilse; Brakhage Axel A; Savoldi Marcela; Goldman Maria Helena S; da Silva Ferreira Márcia Eliana; Goldman Gustavo Henrique
Molecular characterization of the Aspergillus fumigatus NCS-1 homologue, NcsA.
Molecular genetics and genomics : MGG 2008;280(6):483-95.
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2008: Spröte Petra; Hynes Michael J; Hortschansky Peter; Shelest Ekaterina; Scharf Daniel H; Wolke Sandra M; Brakhage Axel A
Identification of the novel penicillin biosynthesis gene aatB of Aspergillus nidulans and its putative evolutionary relationship to this fungal secondary metabolism gene cluster.
Molecular microbiology 2008;70(2):445-61.
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2008: Schrettl Markus; Kim H Stanley; Eisendle Martin; Kragl Claudia; Nierman William C; Heinekamp Thorsten; Werner Ernst R; Jacobsen Ilse; Illmer Paul; Yi Hyojeong; Brakhage Axel A; Haas Hubertus
SreA-mediated iron regulation in Aspergillus fumigatus.
Molecular microbiology 2008;70(1):27-43.
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2008: Grosse Christina; Heinekamp Thorsten; Kniemeyer Olaf; Gehrke Alexander; Brakhage Axel A
Protein kinase A regulates growth, sporulation, and pigment formation in Aspergillus fumigatus.
Applied and environmental microbiology 2008;74(15):4923-33.
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2008: Valiante Vito; Heinekamp Thorsten; Jain Radhika; Härtl Albert; Brakhage Axel A
The mitogen-activated protein kinase MpkA of Aspergillus fumigatus regulates cell wall signaling and oxidative stress response.
Fungal genetics and biology : FG & B 2008;45(5):618-27.
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2008: Erhard Marcel; Hipler Uta-Christina; Burmester Anke; Brakhage Axel A; Wöstemeyer Johannes
Identification of dermatophyte species causing onychomycosis and tinea pedis by MALDI-TOF mass spectrometry.
Experimental dermatology 2008;17(4):356-61.
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2008: Behnsen Judith; Hartmann Andrea; Schmaler Jeannette; Gehrke Alexander; Brakhage Axel A; Zipfel Peter F
The opportunistic human pathogenic fungus Aspergillus fumigatus evades the host complement system.
Infection and immunity 2008;76(2):820-7.
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2008: Ibrahim-Granet Oumaïma; Dubourdeau Marc; Latgé Jean-Paul; Ave Patrick; Huerre Michel; Brakhage Axel A; Brock Matthias
Methylcitrate synthase from Aspergillus fumigatus is essential for manifestation of invasive aspergillosis.
Cellular microbiology 2008;10(1):134-48.
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2008: Brakhage Axel A; Schuemann Julia; Bergmann Sebastian; Scherlach Kirstin; Schroeckh Volker; Hertweck Christian
Activation of fungal silent gene clusters: a new avenue to drug discovery.
Progress in drug research. Fortschritte der Arzneimittelforschung. Progrès des recherches pharmaceutiques 2008;66():1, 3-12.
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2007: Lessing Franziska; Kniemeyer Olaf; Wozniok Iwona; Loeffler Juergen; Kurzai Oliver; Haertl Albert; Brakhage Axel A
The Aspergillus fumigatus transcriptional regulator AfYap1 represents the major regulator for defense against reactive oxygen intermediates but is dispensable for pathogenicity in an intranasal mouse infection model.
Eukaryotic cell 2007;6(12):2290-302.
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2007: Volling Katrin; Brakhage Axel A; Saluz Hans Peter
Apoptosis inhibition of alveolar macrophages upon interaction with conidia of Aspergillus fumigatus.
FEMS microbiology letters 2007;275(2):250-4.
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2007: Thön Marcel; Al-Abdallah Qusai; Hortschansky Peter; Brakhage Axel A
The thioredoxin system of the filamentous fungus Aspergillus nidulans: impact on development and oxidative stress response.
The Journal of biological chemistry 2007;282(37):27259-69.
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2007: Hortschansky Peter; Eisendle Martin; Al-Abdallah Qusai; Schmidt André D; Bergmann Sebastian; Thön Marcel; Kniemeyer Olaf; Abt Beate; Seeber Birgit; Werner Ernst R; Kato Masashi; Brakhage Axel A; Haas Hubertus
Interaction of HapX with the CCAAT-binding complex--a novel mechanism of gene regulation by iron.
The EMBO journal 2007;26(13):3157-68.
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2007: Spröte Petra; Brakhage Axel A
The light-dependent regulator velvet A of Aspergillus nidulans acts as a repressor of the penicillin biosynthesis.
Archives of microbiology 2007;188(1):69-79.
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2007: Bergmann Sebastian; Schümann Julia; Scherlach Kirstin; Lange Corinna; Brakhage Axel A; Hertweck Christian
Genomics-driven discovery of PKS-NRPS hybrid metabolites from Aspergillus nidulans.
Nature chemical biology 2007;3(4):213-7.
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2007: Schöbel Felicitas; Ibrahim-Granet Oumaïma; Avé Patrick; Latgé Jean-Paul; Brakhage Axel A; Brock Matthias
Aspergillus fumigatus does not require fatty acid metabolism via isocitrate lyase for development of invasive aspergillosis.
Infection and immunity 2007;75(3):1237-44.
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2007: da Silva Ferreira Márcia Eliana; Heinekamp Thorsten; Härtl Albert; Brakhage Axel A; Semighini Camile P; Harris Steven D; Savoldi Marcela; de Gouvêa Paula Fagundes; de Souza Goldman Maria Helena; Goldman Gustavo H
Functional characterization of the Aspergillus fumigatus calcineurin.
Fungal genetics and biology : FG & B 2007;44(3):219-30.
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2007: Behnsen Judith; Narang Priyanka; Hasenberg Mike; Gunzer Frank; Bilitewski Ursula; Klippel Nina; Rohde Manfred; Brock Matthias; Brakhage Axel A; Gunzer Matthias
Environmental dimensionality controls the interaction of phagocytes with the pathogenic fungi Aspergillus fumigatus and Candida albicans.
PLoS pathogens 2007;3(2):e13.
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2007: Luther Kathrin; Torosantucci Antonella; Brakhage Axel A; Heesemann Jürgen; Ebel Frank
Phagocytosis of Aspergillus fumigatus conidia by murine macrophages involves recognition by the dectin-1 beta-glucan receptor and Toll-like receptor 2.
Cellular microbiology 2007;9(2):368-81.
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2006: Sugareva Venelina; Härtl Albert; Brock Matthias; Hübner Katrin; Rohde Manfred; Heinekamp Thorsten; Brakhage Axel A
Characterisation of the laccase-encoding gene abr2 of the dihydroxynaphthalene-like melanin gene cluster of Aspergillus fumigatus.
Archives of microbiology 2006;186(5):345-55.
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2006: Kupfahl Claudio; Heinekamp Thorsten; Geginat Gernot; Ruppert Thomas; Härtl Albert; Hof Herbert; Brakhage Axel A
Deletion of the gliP gene of Aspergillus fumigatus results in loss of gliotoxin production but has no effect on virulence of the fungus in a low-dose mouse infection model.
Molecular microbiology 2006;62(1):292-302.
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2006: da Silva Ferreira Márcia Eliana; Malavazi Iran; Savoldi Marcela; Brakhage Axel A; Goldman Maria Helena S; Kim H Stanley; Nierman William C; Goldman Gustavo H
Transcriptome analysis of Aspergillus fumigatus exposed to voriconazole.
Current genetics 2006;50(1):32-44.
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2006: Ebel Frank; Schwienbacher Monika; Beyer Jennifer; Heesemann Jürgen; Brakhage Axel A; Brock Matthias
Analysis of the regulation, expression, and localisation of the isocitrate lyase from Aspergillus fumigatus, a potential target for antifungal drug development.
Fungal genetics and biology : FG & B 2006;43(7):476-89.
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2006: Herrmann Martina; Spröte Petra; Brakhage Axel A
Protein kinase C (PkcA) of Aspergillus nidulans is involved in penicillin production.
Applied and environmental microbiology 2006;72(4):2957-70.
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2006: Kniemeyer Olaf; Lessing Franziska; Scheibner Olaf; Hertweck Christian; Brakhage Axel A
Optimisation of a 2-D gel electrophoresis protocol for the human-pathogenic fungus Aspergillus fumigatus.
Current genetics 2006;49(3):178-89.
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2006: da Silva Ferreira Márcia Eliana; Kress Marcia R V Z; Savoldi Marcela; Goldman Maria Helena S; Härtl Albert; Heinekamp Thorsten; Brakhage Axel A; Goldman Gustavo H
The akuB(KU80) mutant deficient for nonhomologous end joining is a powerful tool for analyzing pathogenicity in Aspergillus fumigatus.
Eukaryotic cell 2006;5(1):207-11.
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2005: Brakhage Axel A
Systemic fungal infections caused by Aspergillus species: epidemiology, infection process and virulence determinants.
Current drug targets 2005;6(8):875-86.
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2005: Goda Hideya; Nagase Takashi; Tanoue Shinjiro; Sugiyama Junya; Steidl Stefan; Tüncher André; Kobayashi Tetsuo; Tsukagoshi Norihiro; Brakhage Axel A; Kato Masashi
Nuclear translocation of the heterotrimeric CCAAT binding factor of Aspergillus oryzae is dependent on two redundant localising signals in a single subunit.
Archives of microbiology 2005;184(2):93-100.
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2005: Tüncher André; Spröte Petra; Gehrke Alexander; Brakhage Axel A
The CCAAT-binding complex of eukaryotes: evolution of a second NLS in the HapB subunit of the filamentous fungus Aspergillus nidulans despite functional conservation at the molecular level between yeast, A.nidulans and human.
Journal of molecular biology 2005;352(3):517-33.
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2005: Maerker Claudia; Rohde Manfred; Brakhage Axel A; Brock Matthias
Methylcitrate synthase from Aspergillus fumigatus. Propionyl-CoA affects polyketide synthesis, growth and morphology of conidia.
The FEBS journal 2005;272(14):3615-30.
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2005: Brakhage Axel A; Al-Abdallah Qusai; Tüncher André; Spröte Petra
Evolution of beta-lactam biosynthesis genes and recruitment of trans-acting factors.
Phytochemistry 2005;66(11):1200-10.
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2005: Schmidt André D; Heinekamp Thorsten; Matuschek Markus; Liebmann Burghard; Bollschweiler Claus; Brakhage Axel A
Analysis of mating-dependent transcription of Blakeslea trispora carotenoid biosynthesis genes carB and carRA by quantitative real-time PCR.
Applied microbiology and biotechnology 2005;67(4):549-55.
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2005: Brakhage A A; Liebmann B
Aspergillus fumigatus conidial pigment and cAMP signal transduction: significance for virulence.
Medical mycology : official publication of the International Society for Human and Animal Mycology 2005;43 Suppl 1():S75-82.
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2004: Steidl Stefan; Tüncher André; Goda Hideya; Guder Corina; Papadopoulou Natalia; Kobayashi Tetsuo; Tsukagoshi Norihiro; Kato Masashi; Brakhage Axel A
A single subunit of a heterotrimeric CCAAT-binding complex carries a nuclear localization signal: piggy back transport of the pre-assembled complex to the nucleus.
Journal of molecular biology 2004;342(2):515-24.
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2004: Liebmann Burghard; Müller Meike; Braun Armin; Brakhage Axel A
The cyclic AMP-dependent protein kinase a network regulates development and virulence in Aspergillus fumigatus.
Infection and immunity 2004;72(9):5193-203.
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2004: Liebmann Burghard; Mühleisen Thomas W; Müller Meike; Hecht Matthias; Weidner Gerhard; Braun Armin; Brock Matthias; Brakhage Axel A
Deletion of the Aspergillus fumigatus lysine biosynthesis gene lysF encoding homoaconitase leads to attenuated virulence in a low-dose mouse infection model of invasive aspergillosis.
Archives of microbiology 2004;181(5):378-83.
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2004: Tüncher André; Reinke Hans; Martic Goran; Caruso Maria Louise; Brakhage Axel A
A basic-region helix-loop-helix protein-encoding gene (devR) involved in the development of Aspergillus nidulans.
Molecular microbiology 2004;52(1):227-41.
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2004: Brakhage Axel A; Spröte Petra; Al-Abdallah Qusai; Gehrke Alexander; Plattner Hans; Tüncher André
Regulation of penicillin biosynthesis in filamentous fungi.
Advances in biochemical engineering/biotechnology 2004;88():45-90.
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2003: Liebmann B; Gattung S; Jahn B; Brakhage A A
cAMP signaling in Aspergillus fumigatus is involved in the regulation of the virulence gene pksP and in defense against killing by macrophages.
Molecular genetics and genomics : MGG 2003;269(3):420-35.
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2003: Langfelder Kim; Streibel Martin; Jahn Bernhard; Haase Gerhard; Brakhage Axel A
Biosynthesis of fungal melanins and their importance for human pathogenic fungi.
Fungal genetics and biology : FG & B 2003;38(2):143-58.
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2003: Busch Silke; Bode Helge B; Brakhage Axel A; Braus Gerhard H
Impact of the cross-pathway control on the regulation of lysine and penicillin biosynthesis in Aspergillus nidulans.
Current genetics 2003;42(4):209-19.
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2002: Jahn Bernhard; Langfelder Kim; Schneider Ulrike; Schindel Christine; Brakhage Axel A
PKSP-dependent reduction of phagolysosome fusion and intracellular kill of Aspergillus fumigatus conidia by human monocyte-derived macrophages.
Cellular microbiology 2002;4(12):793-803.
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2002: Caruso Maria Louise; Litzka Olivier; Martic Goran; Lottspeich Friedrich; Brakhage Axel A
Novel basic-region helix-loop-helix transcription factor (AnBH1) of Aspergillus nidulans counteracts the CCAAT-binding complex AnCF in the promoter of a penicillin biosynthesis gene.
Journal of molecular biology 2002;323(3):425-39.
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2002: Langfelder Kim; Gattung Stephanie; Brakhage Axel A
A novel method used to delete a new Aspergillus fumigatus ABC transporter-encoding gene.
Current genetics 2002;41(4):268-74.
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2002: Bañuelos O; Casqueiro J; Steidl S; Gutiérrez S; Brakhage A; Martín J F
Subcellular localization of the homocitrate synthase in Penicillium chrysogenum.
Molecular genetics and genomics : MGG 2002;266(5):711-9.
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2002: Brakhage Axel A; Langfelder Kim
Menacing mold: the molecular biology of Aspergillus fumigatus.
Annual review of microbiology 2002;56():433-55.
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2001: Langfelder K; Philippe B; Jahn B; Latgé J P; Brakhage A A
Differential expression of the Aspergillus fumigatus pksP gene detected in vitro and in vivo with green fluorescent protein.
Infection and immunity 2001;69(10):6411-8.
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2001: Tanaka A; Kamei K; Tanoue S; Papagiannopoulos P; Steidl S; Brakhage A A; Davis M A; Hynes M J; Kato M; Kobayashi T; Tsukagoshi N
AoHapB, AoHapC and AoHapE, subunits of the Aspergillus oryzae CCAAT-binding complex, are functionally interchangeable with the corresponding subunits in Aspergillus nidulans.
Current genetics 2001;39(3):175-82.
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2001: Steidl S; Hynes M J; Brakhage A A
The Aspergillus nidulans multimeric CCAAT binding complex AnCF is negatively autoregulated via its hapB subunit gene.
Journal of molecular biology 2001;306(4):643-53.
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2001: Weidner G; Steidl S; Brakhage A A
The Aspergillus nidulans homoaconitase gene lysF is negatively regulated by the multimeric CCAAT-binding complex AnCF and positively regulated by GATA sites.
Archives of microbiology 2001;175(2):122-32.
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2000: Heinz W J; Kurzai O; Brakhage A A; Fonzi W A; Korting H C; Frosch M; Mühlschlegel F A
Molecular responses to changes in the environmental pH are conserved between the fungal pathogens Candida dubliniensis and Candida albicans.
International journal of medical microbiology : IJMM 2000;290(3):231-8.
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2000: Jahn B; Boukhallouk F; Lotz J; Langfelder K; Wanner G; Brakhage A A
Interaction of human phagocytes with pigmentless Aspergillus conidia.
Infection and immunity 2000;68(6):3736-9.
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1999: Van Den Brulle J; Steidl S; Brakhage A A
Cloning and characterization of an Aspergillus nidulans gene involved in the regulation of penicillin biosynthesis.
Applied and environmental microbiology 1999;65(12):5222-8.
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1999: Brakhage A A; Andrianopoulos A; Kato M; Steidl S; Davis M A; Tsukagoshi N; Hynes M J
HAP-Like CCAAT-binding complexes in filamentous fungi: implications for biotechnology.
Fungal genetics and biology : FG & B 1999;27(2-3):243-52.
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1999: Litzka O; Then Bergh K; Van den Brulle J; Steidl S; Brakhage A A
Transcriptional control of expression of fungal beta-lactam biosynthesis genes.
Antonie van Leeuwenhoek 1999;75(1-2):95-105.
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1999: Steidl S; Papagiannopoulos P; Litzka O; Andrianopoulos A; Davis M A; Brakhage A A; Hynes M J
AnCF, the CCAAT binding complex of Aspergillus nidulans, contains products of the hapB, hapC, and hapE genes and is required for activation by the pathway-specific regulatory gene amdR.
Molecular and cellular biology 1999;19(1):99-106.
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1999: Brakhage A A; Langfelder K; Wanner G; Schmidt A; Jahn B
Pigment biosynthesis and virulence.
Contributions to microbiology 1999;2():205-15.
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1999: d'Enfert C; Weidner G; Mol P C; Brakhage A A
Transformation systems of Aspergillus fumigatus. New tools to investigate fungal virulence.
Contributions to microbiology 1999;2():149-66.
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1998: Langfelder K; Jahn B; Gehringer H; Schmidt A; Wanner G; Brakhage A A
Identification of a polyketide synthase gene (pksP) of Aspergillus fumigatus involved in conidial pigment biosynthesis and virulence.
Medical microbiology and immunology 1998;187(2):79-89.
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1998: Brakhage A A
Molecular regulation of beta-lactam biosynthesis in filamentous fungi.
Microbiology and molecular biology reviews : MMBR 1998;62(3):547-85.
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1998: Weidner G; d'Enfert C; Koch A; Mol P C; Brakhage A A
Development of a homologous transformation system for the human pathogenic fungus Aspergillus fumigatus based on the pyrG gene encoding orotidine 5'-monophosphate decarboxylase.
Current genetics 1998;33(5):378-85.
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1998: Then Bergh K; Brakhage A A
Regulation of the Aspergillus nidulans penicillin biosynthesis gene acvA (pcbAB) by amino acids: implication for involvement of transcription factor PACC.
Applied and environmental microbiology 1998;64(3):843-9.
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1998: Litzka O; Papagiannopolous P; Davis M A; Hynes M J; Brakhage A A
The penicillin regulator PENR1 of Aspergillus nidulans is a HAP-like transcriptional complex.
European journal of biochemistry / FEBS 1998;251(3):758-67.
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1997: Jahn B; Koch A; Schmidt A; Wanner G; Gehringer H; Bhakdi S; Brakhage A A
Isolation and characterization of a pigmentless-conidium mutant of Aspergillus fumigatus with altered conidial surface and reduced virulence.
Infection and immunity 1997;65(12):5110-7.
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1997: Weidner G; Steffan B; Brakhage A A
The Aspergillus nidulans lysF gene encodes homoaconitase, an enzyme involved in the fungus-specific lysine biosynthesis pathway.
Molecular & general genetics : MGG 1997;255(3):237-47.
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1997: Brakhage A A
Molecular regulation of penicillin biosynthesis in Aspergillus (Emericella) nidulans.
FEMS microbiology letters 1997;148(1):1-10.
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1996: Bergh K T; Litzka O; Brakhage A A
Identification of a major cis-acting DNA element controlling the bidirectionally transcribed penicillin biosynthesis genes acvA (pcbAB) and ipnA (pcbC) of Aspergillus nidulans.
Journal of bacteriology 1996;178(13):3908-16.
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1996: Litzka O; Then Bergh K; Brakhage A A
The Aspergillus nidulans penicillin-biosynthesis gene aat (penDE) is controlled by a CCAAT-containing DNA element.
European journal of biochemistry / FEBS 1996;238(3):675-82.
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1995: Litzka O; Bergh K T; Brakhage A A
Analysis of the regulation of the Aspergillus nidulans penicillin biosynthesis gene aat (penDE), which encodes acyl coenzyme A:6-aminopenicillanic acid acyltransferase.
Molecular & general genetics : MGG 1995;249(5):557-69.
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1995: Brakhage A A; Van den Brulle J
Use of reporter genes to identify recessive trans-acting mutations specifically involved in the regulation of Aspergillus nidulans penicillin biosynthesis genes.
Journal of bacteriology 1995;177(10):2781-8.
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1994: Brakhage A A; Browne P; Turner G
Analysis of the regulation of penicillin biosynthesis in Aspergillus nidulans by targeted disruption of the acvA gene.
Molecular & general genetics : MGG 1994;242(1):57-64.
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1992: Brakhage A A; Turner G
L-lysine repression of penicillin biosynthesis and the expression of penicillin biosynthesis genes acvA and ipnA in Aspergillus nidulans.
FEMS microbiology letters 1992;77(1-3):123-7.
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1992: Brakhage A A; Browne P; Turner G
Regulation of Aspergillus nidulans penicillin biosynthesis and penicillin biosynthesis genes acvA and ipnA by glucose.
Journal of bacteriology 1992;174(11):3789-99.
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