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Yi-Ching Wang

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Publications

TOP 3
Jia-Yang Chen; Yu-Ching Chiou; Wen-Shan Li; Jiunn-Min Shieh; Yen-An Tang; Yi-Ching Wang
A Synthetic Podophyllotoxin Derivative Exerts Anti-Cancer Effects by Inducing Mitotic Arrest and Pro-Apoptotic ER Stress in Lung Cancer Preclinical Models.
Hsin-Yi Chang; Hsuan-Cheng Huang; Tsui-Chin Huang; Yi-Ching Wang; Pan-Chyr Yang; Hsueh-Fen Juan
Ectopic ATP synthase blockade suppresses lung adenocarcinoma growth by activating the unfolded protein response.
Fang-Yi Lo; Hsiung-Ting Chen; Hung-Chi Cheng; Han-Shui Hsu; Yi-Ching Wang
Overexpression of PAFAH1B1 is associated with tumor metastasis and poor survival in non-small cell lung cancer.

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All Publications

2013: Jia-Yang Chen; Yu-Ching Chiou; Wen-Shan Li; Jiunn-Min Shieh; Yen-An Tang; Yi-Ching Wang
A Synthetic Podophyllotoxin Derivative Exerts Anti-Cancer Effects by Inducing Mitotic Arrest and Pro-Apoptotic ER Stress in Lung Cancer Preclinical Models.
PloS one 2013;8(4):e62082.
2012: Hsin-Yi Chang; Hsuan-Cheng Huang; Tsui-Chin Huang; Yi-Ching Wang; Pan-Chyr Yang; Hsueh-Fen Juan
Ectopic ATP synthase blockade suppresses lung adenocarcinoma growth by activating the unfolded protein response.
Cancer research 2012;72(18):4696-706.
2012: Fang-Yi Lo; Hsiung-Ting Chen; Hung-Chi Cheng; Han-Shui Hsu; Yi-Ching Wang
Overexpression of PAFAH1B1 is associated with tumor metastasis and poor survival in non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) 2012;77(3):585-92.
2012: Yen-An Tang; Yo-Ting Tsai; Chih-Yi Chen; Han-Shui Hsu; Ruo-Kai Lin; Yi-Chieh Yang; Yi-Ching Wang
MDM2 overexpression deregulates the transcriptional control of RB/E2F leading to DNA methyltransferase 3A overexpression in lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(16):4325-33.
2012: Sin-Ming Huang; Wen-Shan Li; Kwok-Tung Lu; Shivaji V More; Mei-Yu Chen; Pei-Chun Hsu; Yi-Ching Wang
The novel indole compound SK228 induces apoptosis and FAK/Paxillin disruption in tumor cell lines and inhibits growth of tumor graft in the nude mouse.
International journal of cancer. Journal international du cancer 2012;131(3):722-32.
2012: Ying-Chuen Lai; Chou-Shiang Wang; Yi-Ching Wang; Yu-Ling Hsu; Lee-Ming Chuang
Falsely decreased HbA1c in a type 2 diabetic patient treated with dapsone.
Journal of the Formosan Medical Association = Taiwan yi zhi 2012;111(2):109-12.
2012: Fang-Yi Lo; Suvobroto Nandi; Ravi Salgia; Fang-Yu Tsai; I-Shou Chang; Jer-Wei Chang; Yann-Jang Chen; Han-Shui Hsu; Shiu-Feng Kathy Huang; Shih Sheng Jiang; Rajani Kanteti; Yi-Ching Wang
The database of chromosome imbalance regions and genes resided in lung cancer from Asian and Caucasian identified by array-comparative genomic hybridization.
BMC cancer 2012;12():235.
2011: Fang-Yi Lo; Ravi Salgia; Yi-Hung Carol Tan; Hung-Chi Cheng; Yi-Ching Wang
An E3 ubiquitin ligase: c-Cbl: a new therapeutic target of lung cancer.
Cancer 2011;117(23):5344-50.
2011: Jia-Yang Chen; Yen-An Tang; Sin-Ming Huang; Hsueh-Fen Juan; Li-Wha Wu; Ying-Chieh Sun; Szu-Chi Wang; Kuan-Wei Wu; Gopula Balraj; Tzu-Ting Chang; Wen-Shan Li; Hung-Chi Cheng; Yi-Ching Wang
A novel sialyltransferase inhibitor suppresses FAK/paxillin signaling and cancer angiogenesis and metastasis pathways.
Cancer research 2011;71(2):473-83.
2011: Sin-Ming Huang; Kwok-Tung Lu; Yi-Ching Wang
ATM/ATR and SMAD3 pathways contribute to 3-indole-induced G₁ arrest in cancer cells and xenograft models.
Anticancer research 2011;31(1):203-8.
2010: Chung-Fan Lee; Derick S-C Ou; SB Lee; Liang-Hao Chang; Ruo-Kai Lin; Ying-Shiuan Li; Anup K Upadhyay; Xiaodong Cheng; Yi-Ching Wang; Han-Shui Hsu; Michael Hsiao; Cheng-Wen Wu; Li-Jung Juan
hNaa10p contributes to tumorigenesis by facilitating DNMT1-mediated tumor suppressor gene silencing.
The Journal of clinical investigation 2010;120(8):2920-30.
2010: Ruo-Kai Lin; Chiu-Yi Wu; Jer-Wei Chang; Li-Jung Juan; Han-Shui Hsu; Chih-Yi Chen; Yun-Yueh Lu; Yen-An Tang; Yi-Chieh Yang; Pan-Chyr Yang; Yi-Ching Wang
Dysregulation of p53/Sp1 control leads to DNA methyltransferase-1 overexpression in lung cancer.
Cancer research 2010;70(14):5807-17.
2010: Ruo-Kai Lin; Yi-Shuan Hsieh; Pinpin Lin; Han-Shui Hsu; Chih-Yi Chen; Yen-An Tang; Chung-Fan Lee; Yi-Ching Wang
The tobacco-specific carcinogen NNK induces DNA methyltransferase 1 accumulation and tumor suppressor gene hypermethylation in mice and lung cancer patients.
The Journal of clinical investigation 2010;120(2):521-32.
2010: Jer-Wei Chang; Han-Shui Hsu; Huey-Juin Ni; Ching-Ting Chuang; Chi-Hui Hsiung; Hui-Ming (Tim) Huang; Yi-Ching Wang
Distinct epigenetic domains separated by a CTCF bound insulator between the tandem genes, BLU and RASSF1A.
PloS one 2010;5(9):e12847.
2010: Yi-Hung Carol Tan; Soundararajan Krishnaswamy; Suvobroto Nandi; Rajani Kanteti; Sapana Vora; Kenan Onel; Rifat Hasina; Fang-Yi Lo; Essam El-Hashani; Gustavo Cervantes; Matthew Robinson; Han-Shui Hsu; Stephen C Kales; Stanley Lipkowitz; Theodore Karrison; Martin Sattler; Everett E Vokes; Yi-Ching Wang; Ravi Salgia
CBL is frequently altered in lung cancers: its relationship to mutations in MET and EGFR tyrosine kinases.
PloS one 2010;5(1):e8972.
2009: Anna Fen-Yau Li; Po-Kuei Hsu; Ching Tzao; Yi-Ching Wang; I-Chun Hung; Min-Hsiung Huang; Han-Shui Hsu
Reduced axin protein expression is associated with a poor prognosis in patients with squamous cell carcinoma of esophagus.
Annals of surgical oncology 2009;16(9):2486-93.
2009: Ruo-Chia Tseng; Chin-Chu Lee; Han-Shui Hsu; Ching Tzao; Yi-Ching Wang
Distinct HIC1-SIRT1-p53 loop deregulation in lung squamous carcinoma and adenocarcinoma patients.
Neoplasia (New York, N.Y.) 2009;11(8):763-70.
2009: Ruo-Chia Tseng; Feng-Jen Hsieh; Chuen-Ming Shih; Han-Shui Hsu; Chih-Yi Chen; Yi-Ching Wang
Lung cancer susceptibility and prognosis associated with polymorphisms in the nonhomologous end-joining pathway genes: a multiple genotype-phenotype study.
Cancer 2009;115(13):2939-48.
2008: Ching-Hsiao Lee; Ching-Fa Yao; Sin-Ming Huang; Shengkai Ko; Yi-Hung Tan; Guey-Jen Lee-Chen; Yi-Ching Wang
Novel 2-step synthetic indole compound 1,1,3-tri(3-indolyl)cyclohexane inhibits cancer cell growth in lung cancer cells and xenograft models.
Cancer 2008;113(4):815-25.
2008: Ruo-Chia Tseng; R-K Lin; C-K Wen; C Tseng; H-S Hsu; W-H Hsu; Yi-Ching Wang
Epigenetic silencing of AXIN2/betaTrCP and deregulation of p53-mediated control lead to wild-type beta-catenin nuclear accumulation in lung tumorigenesis.
Oncogene 2008;27(32):4488-96.
2008: Po-Kuei Hsu; Anna Fen-Yau Li; Yi-Ching Wang; Chih-Cheng Hsieh; Min-Hsiung Huang; Wen-Hu Hsu; Han-Shui Hsu
Reduced membranous beta-catenin protein expression is associated with metastasis and poor prognosis in squamous cell carcinoma of the esophagus.
The Journal of thoracic and cardiovascular surgery 2008;135(5):1029-35.
2008: Yi-Hung Tan; Kung-Hsueh Lee; Topp Lin; Ying-Chieh Sun; Hsiu Mei Hsieh-Li; Hsueh-Fen Juan; Yi-Ching Wang
Cytotoxicity and proteomics analyses of OSU03013 in lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(6):1823-30.
2008: Ruo-Chia Tseng; Feng-Jen Hsieh; Han-Shui Hsu; Yi-Ching Wang
Minimal deletion regions in lung squamous cell carcinoma: association with abnormality of the DNA double-strand break repair genes and their applications on gene identification and prognostic biomarkers.
Lung cancer (Amsterdam, Netherlands) 2008;59(3):332-9.
2007: Han-Shui Hsu; Tsz-Pei Chen; Chiao-Kai Wen; C-H Hung; C-Y Chen; Jung-Ta Chen; Yi-Ching Wang
Multiple genetic and epigenetic biomarkers for lung cancer detection in cytologically negative sputum and a nested case-control study for risk assessment.
The Journal of pathology 2007;213(4):412-9.
2007: Ruo-Kai Lin; Chun-Hua Hsu; Yi-Ching Wang
Mithramycin A inhibits DNA methyltransferase and metastasis potential of lung cancer cells.
Anti-cancer drugs 2007;18(10):1157-64.
2007: Han-Shui Hsu; Tsz-Pei Chen; Chein-Hui Hung; Chiao-Kai Wen; Ruo-Kai Lin; Hui-Chen Lee; Yi-Ching Wang
Characterization of a multiple epigenetic marker panel for lung cancer detection and risk assessment in plasma.
Cancer 2007;110(9):2019-26.
2007: Ming-Ni Lee; Ruo-Chia Tseng; Han-Shui Hsu; Jia-Yang Chen; Ching Tzao; William L Ho; Yi-Ching Wang
Epigenetic inactivation of the chromosomal stability control genes BRCA1, BRCA2, and XRCC5 in non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(3):832-8.
2007: Ruo-Kai Lin; Han-Shui Hsu; Jer-Wei Chang; Chih-Yi Chen; Jung-Ta Chen; Yi-Ching Wang
Alteration of DNA methyltransferases contributes to 5'CpG methylation and poor prognosis in lung cancer.
Lung cancer (Amsterdam, Netherlands) 2007;55(2):205-13.
2006: Yi-Ching Wang; Han-Shui Hsu; Tsz-Pei Chen; Jung-Ta Chen
Molecular diagnostic markers for lung cancer in sputum and plasma.
Annals of the New York Academy of Sciences 2006;1075():179-84.
2005: Ruo-Chia Tseng; Jer-Wei Chang; Feng-Jen Hsien; Ya-Hui Chang; Chin-Fu Hsiao; Jung-Ta Chen; Chih-Yi Chen; Yuh-Shan Jou; Yi-Ching Wang
Genomewide loss of heterozygosity and its clinical associations in non small cell lung cancer.
International journal of cancer. Journal international du cancer 2005;117(2):241-7.
2005: Han-Shui Hsu; Chiao-Kai Wen; Yen-An Tang; Ruo-Kai Lin; Wing-Yin Li; Wen-Hu Hsu; Yi-Ching Wang
Promoter hypermethylation is the predominant mechanism in hMLH1 and hMSH2 deregulation and is a poor prognostic factor in nonsmoking lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(15):5410-6.
2005: Yi-Ching Wang; Ruo-Kai Lin; Yi-Hung Tan; Jung-Ta Chen; Chih-Yi Chen; Yi-Ching Wang
Wild-type p53 overexpression and its correlation with MDM2 and p14ARF alterations: an alternative pathway to non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(1):154-64.
2004: Han-Shui Hsu; Yi-Ching Wang; Ruo-Chia Tseng; Jer-Wei Chang; Jung-Ta Chen; Chuen-Ming Shih; Chih-Yi Chen; Yi-Ching Wang
5' cytosine-phospho-guanine island methylation is responsible for p14ARF inactivation and inversely correlates with p53 overexpression in resected non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(14):4734-41.
2003: Yi-Ching Wang; Pei-Jung Lee; Chuen-Ming Shih; Hsing-Yu Chen; Chin-Chu Lee; Yuan-Yen Chang; Yu-Ting Hsu; Ying-Ju Liang; Li-Ya Wang; Wen-Hua Han; Yu-Chieh Wang
Damage formation and repair efficiency in the p53 gene of cell lines and blood lymphocytes assayed by multiplex long quantitative polymerase chain reaction.
Analytical biochemistry 2003;319(2):206-15.
2003: Yi-Ching Wang; Yung-Pin Lu; Ruo-Chia Tseng; Ruo-Kai Lin; Jer-Wei Chang; Jung-Ta Chen; Chuen-Ming Shih; Chih-Yi Chen
Inactivation of hMLH1 and hMSH2 by promoter methylation in primary non-small cell lung tumors and matched sputum samples.
The Journal of clinical investigation 2003;111(6):887-95.
2002: Chuen-Ming Shih; Yen-Ya Kuo; Yi-Ching Wang; Shiou-Ling Jian; Yu-Ting Hsu; Hsing-Yi Wu; Ming-Woei Guo; Yu-Chieh Wang
Association of L-myc polymorphism with lung cancer susceptibility and prognosis in relation to age-selected controls and stratified cases.
Lung cancer (Amsterdam, Netherlands) 2002;36(2):125-32.
2002: Jung-Ta Chen; Yi-Chun Chen; Yi-Ching Wang; Ruo-Chia Tseng; Chih-Yi Chen; Yi-Ching Wang
Alterations of the p16(ink4a) gene in resected nonsmall cell lung tumors and exfoliated cells within sputum.
International journal of cancer. Journal international du cancer 2002;98(5):724-31.
2002: William L Ho; Jer-Wei Chang; Ruo-Chia Tseng; Jung-Ta Chen; Chih-Yi Chen; Yuh-Shan Jou; Yi-Ching Wang
Loss of heterozygosity at loci of candidate tumor suppressor genes in microdissected primary non-small cell lung cancer.
Cancer detection and prevention 2002;26(5):343-9.
2001: Jung-Ta Chen; Y C Chen; Chih-Yi Chen; Yi-Ching Wang
Loss of p16 and/or pRb protein expression in NSCLC. An immunohistochemical and prognostic study.
Lung cancer (Amsterdam, Netherlands) 2001;31(2-3):163-70.
2000: Chuen-Ming Shih; P T Lin; H C Wang; W C Huang; Yi-Ching Wang
Lack of evidence of association of p21WAF1/CIP1 polymorphism with lung cancer susceptibility and prognosis in Taiwan.
Japanese journal of cancer research : Gann 2000;91(1):9-15.