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Andrew Ward

Research Profile

Living Beings

Chemicals & Drugs

Physiology

Disorders

Wilms' Tumor

Genes & Molecular Sequences

Procedures

Crosses, Genetic

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Molecular Sequence Data

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Publications

TOP 3
Alastair S Garfield; Michael Cowley; Florentia M Smith; Kim Moorwood; Joanne E Stewart-Cox; Kerry Gilroy; Sian Baker; Jing Xia; Jeffrey W Dalley; Laurence D Hurst; Lawrence S Wilkinson; Anthony R Isles; Andrew Ward
Distinct physiological and behavioural functions for parental alleles of imprinted Grb10.
Asha Recino; Victoria Sherwood; Amy Flaxman; Wendy N Cooper; Farida Latif; Andrew Ward; Andrew D Chalmers
Human RASSF7 regulates the microtubule cytoskeleton and is required for spindle formation, Aurora B activation and chromosomal congression during mitosis.
Wilhelm Engström; Andrew Ward; K Moorwood
The role of scaffold proteins in JNK signalling.

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All Publications

2011: Alastair S Garfield; Michael Cowley; Florentia M Smith; Kim Moorwood; Joanne E Stewart-Cox; Kerry Gilroy; Sian Baker; Jing Xia; Jeffrey W Dalley; Laurence D Hurst; Lawrence S Wilkinson; Anthony R Isles; Andrew Ward
Distinct physiological and behavioural functions for parental alleles of imprinted Grb10.
Nature 2011;469(7331):534-8.
2010: Asha Recino; Victoria Sherwood; Amy Flaxman; Wendy N Cooper; Farida Latif; Andrew Ward; Andrew D Chalmers
Human RASSF7 regulates the microtubule cytoskeleton and is required for spindle formation, Aurora B activation and chromosomal congression during mitosis.
The Biochemical journal 2010;430(2):207-13.
2010: Wilhelm Engström; Andrew Ward; K Moorwood
The role of scaffold proteins in JNK signalling.
Cell proliferation 2010;43(1):56-66.
2010: Victoria Sherwood; Asha Recino; Alex Jeffries; Andrew Ward; Andrew D Chalmers
The N-terminal RASSF family: a new group of Ras-association-domain-containing proteins, with emerging links to cancer formation.
The Biochemical journal 2010;425(2):303-11.
2010: Marika Charalambous; Michael Cowley; Fleur Geoghegan; Florentia M Smith; Elizabeth J Radford; Benjamin P Marlow; Christopher F Graham; Laurence D Hurst; Andrew Ward
Maternally-inherited Grb10 reduces placental size and efficiency.
Developmental biology 2010;337(1):1-8.
2009: Anthony R Dallosso; Anne L Hancock; Marianna Szemes; Kim Moorwood; Laxmi Chilukamarri; Hsin-Hao Tsai; Abby Sarkar; Jonathan Barasch; Raisa Vuononvirta; Chris Jones; Kathy Pritchard-Jones; Brigitte Royer-Pokora; Sean Bong Lee; Ceris Owen; Sally Malik; Yi Feng; Marcus Frank; Andrew Ward; Keith W Brown; Karim Malik
Frequent long-range epigenetic silencing of protocadherin gene clusters on chromosome 5q31 in Wilms' tumor.
PLoS genetics 2009;5(11):e1000745.
2009: Lowenna J Holt; Ruth J Lyons; Ashleigh S Ryan; Susan M Beale; Andrew Ward; Gregory J Cooney; Roger J Daly
Dual ablation of Grb10 and Grb14 in mice reveals their combined role in regulation of insulin signaling and glucose homeostasis.
Molecular endocrinology (Baltimore, Md.) 2009;23(9):1406-14.
2009: Catherine J Pink; Siva K Swaminathan; Ian Dunham; Jane Rogers; Andrew Ward; Laurence D Hurst
Evidence that replication-associated mutation alone does not explain between-chromosome differences in substitution rates.
Genome biology and evolution 2009;1():13-22.
2008: Susana Lopes; Xueyan Yang; Jeanette Müller; Thomas J Carney; Anthony R McAdow; Gerd-Jörg Rauch; Arie S Jacoby; Laurence D Hurst; Mariana Delfino-Machín; Pascal Haffter; Robert Geisler; Stephen L Johnson; Andrew Ward; Robert Neil Kelsh
Leukocyte tyrosine kinase functions in pigment cell development.
PLoS genetics 2008;4(3):e1000026.
2007: Anthony R Dallosso; Anne L Hancock; Sally Malik; Ashreena Salpekar; Linda King-Underwood; Kathy Pritchard-Jones; Jo Peters; Kim Moorwood; Andrew Ward; Karim T A Malik; Keith W Brown
Alternately spliced WT1 antisense transcripts interact with WT1 sense RNA and show epigenetic and splicing defects in cancer.
RNA (New York, N.Y.) 2007;13(12):2287-99.
2007: Florentia M Smith; Lowenna J Holt; Alastair S Garfield; Marika Charalambous; Francoise Koumanov; Mark Perry; Reto Bazzani; Steven A Sheardown; Bronwyn D Hegarty; Ruth J Lyons; Gregory J Cooney; Roger J Daly; Andrew Ward
Mice with a disruption of the imprinted Grb10 gene exhibit altered body composition, glucose homeostasis, and insulin signaling during postnatal life.
Molecular and cellular biology 2007;27(16):5871-86.
2007: Diya Lahiri; James R Dutton; Antonio Duarte; Kim Moorwood; Christopher F Graham; Andrew Ward
Nephropathy and defective spermatogenesis in mice transgenic for a single isoform of the Wilms' tumour suppressor protein, WT1-KTS, together with one disrupted Wt1 allele.
Molecular reproduction and development 2007;74(3):300-11.
2006: James R Dutton; D Lahiri; Andrew Ward
Different isoforms of the Wilms' tumour protein WT1 have distinct patterns of distribution and trafficking within the nucleus.
Cell proliferation 2006;39(6):519-35.
2006: Anthony Antonellis; William R Bennett; Treve Menheniott; Arjun B Prasad; Shih-Queen Lee-Lin; Eric Green; Derek Paisley; Robert Neil Kelsh; William J Pavan; Andrew Ward
Deletion of long-range sequences at Sox10 compromises developmental expression in a mouse model of Waardenburg-Shah (WS4) syndrome.
Human molecular genetics 2006;15(2):259-71.
2006: Florentia M Smith; A S Garfield; Andrew Ward
Regulation of growth and metabolism by imprinted genes.
Cytogenetic and genome research 2006;113(1-4):279-91.
2004: Marika Charalambous; Treve Menheniott; William R Bennett; Sharon M Kelly; Ghislaine Dell; Luisa Dandolo; Andrew Ward
An enhancer element at the Igf2/H19 locus drives gene expression in both imprinted and non-imprinted tissues.
Developmental biology 2004;271(2):488-97.
2003: Marika Charalambous; Andrew Ward; Laurence D Hurst
Evidence for a priming effect on maternal resource allocation: implications for interbrood competition.
Proceedings. Biological sciences / The Royal Society 2003;270 Suppl 1():S100-3.
2003: Marika Charalambous; Florentia M Smith; William R Bennett; Tracey E Crew; Francesca Mackenzie; Andrew Ward
Disruption of the imprinted Grb10 gene leads to disproportionate overgrowth by an Igf2-independent mechanism.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(14):8292-7.
2003: William R Bennett; Tracey E Crew; Jonathan M W Slack; Andrew Ward
Structural-proliferative units and organ growth: effects of insulin-like growth factor 2 on the growth of colon and skin.
Development (Cambridge, England) 2003;130(6):1079-88.
1998: A Duarte; A Caricasole; Christopher F Graham; Andrew Ward
Wilms' tumour-suppressor protein isoforms have opposite effects on Igf2 expression in primary embryonic cells, independently of p53 genotype.
British journal of cancer 1998;77(2):253-9.
1997: Ghislaine Dell; Andrew Ward; W Engström
Regulation of a promoter from the mouse insulin like growth factor II gene by glucocorticoids.
FEBS letters 1997;419(2-3):161-5.
1997: Andrew Ward; R Fisher; L Richardson; J A Pooler; S Squire; P Bates; R Shaposhnikov; N Hayward; M Thurston; Christopher F Graham
Genomic regions regulating imprinting and insulin-like growth factor-II promoter 3 activity in transgenics: novel enhancer and silencer elements.
Genes and function 1997;1(1):25-36.
1997: Andrew Ward
Beck-Wiedemann syndrome and Wilms' tumour.
Molecular human reproduction 1997;3(2):157-68.
1996: Melissa H Little; G Holmes; L Pell; A Caricasole; A Duarte; M Law; Andrew Ward; Brandon J Wainwright
A novel target for the Wilms' tumour suppressor protein (WT1) is bound by a unique combination of zinc fingers.
Oncogene 1996;13(7):1461-9.
1996: A Caricasole; A Duarte; S H Larsson; Nicholas D Hastie; Melissa Little; G Holmes; I Todorov; Andrew Ward
RNA binding by the Wilms tumor suppressor zinc finger proteins.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(15):7562-6.
1995: Andrew Ward; J A Pooler; K Miyagawa; A Duarte; Nicholas D Hastie; A Caricasole
Repression of promoters for the mouse insulin-like growth factor II-encoding gene (Igf-2) by products of the Wilms' tumour suppressor gene wt1.
Gene 1995;167(1-2):239-43.
1995: P Bates; R Fisher; Andrew Ward; L Richardson; D J Hill; Christopher F Graham
Mammary cancer in transgenic mice expressing insulin-like growth factor II (IGF-II)
British journal of cancer 1995;72(5):1189-93.
1994: T H Da Costa; D H Williamson; Andrew Ward; P Bates; R Fisher; L Richardson; D J Hill; I C Robinson; Christopher F Graham
High plasma insulin-like growth factor-II and low lipid content in transgenic mice: measurements of lipid metabolism.
The Journal of endocrinology 1994;143(3):433-9.
1994: S Newell; Andrew Ward; C Graham
Discriminating translation of insulin-like growth factor-II (IGF-II) during mouse embryogenesis.
Molecular reproduction and development 1994;39(3):249-58.
1994: Andrew Ward; P Bates; R Fisher; L Richardson; Christopher F Graham
Disproportionate growth in mice with Igf-2 transgenes.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(22):10365-9.
1993: A Caricasole; Andrew Ward
Transactivation of mouse insulin-like growth factor II (IGF-II) gene promoters by the AP-1 complex.
Nucleic acids research 1993;21(8):1873-9.
1993: A Caricasole; Andrew Ward
A luciferase-reporter vector with blue-white selection for rapid subcloning and mutational analysis of eukaryotic promoters.
Gene 1993;124(1):139-40.