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Nicholas Wareham

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Paul J Collings; Cyrus Cooper; Søren Brage; Keith M Godfrey; Nicholas C Harvey; Hazel M Inskip; Charlotte L Ridgway; Nicholas J Wareham; Ulf Ekelund
Physical activity intensity, sedentary time, and body composition in preschoolers.
Brigitte M Sondermeijer; Nicholas J Wareham; S Matthijs Boekholdt; John J P Kastelein; Jamal S Rana; Kay-Tee Khaw
Clinical implications of JUPITER in a contemporary European population: the EPIC-Norfolk prospective population study.
Effrossyni Gkrania-Klotsas; Kay-Tee Khaw; Claudia Langenberg; Robert Luben; Stephen J Sharp; Nicholas J Wareham
Seropositivity and higher immunoglobulin g antibody levels against cytomegalovirus are associated with mortality in the population-based European prospective investigation of cancer-norfolk cohort.

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2013: Paul J Collings; Cyrus Cooper; Søren Brage; Keith M Godfrey; Nicholas C Harvey; Hazel M Inskip; Charlotte L Ridgway; Nicholas J Wareham; Ulf Ekelund
Physical activity intensity, sedentary time, and body composition in preschoolers.
The American journal of clinical nutrition 2013;97(5):1020-8.
2013: Brigitte M Sondermeijer; Nicholas J Wareham; S Matthijs Boekholdt; John J P Kastelein; Jamal S Rana; Kay-Tee Khaw
Clinical implications of JUPITER in a contemporary European population: the EPIC-Norfolk prospective population study.
European heart journal 2013;34(18):1350-7.
2013: Effrossyni Gkrania-Klotsas; Kay-Tee Khaw; Claudia Langenberg; Robert Luben; Stephen J Sharp; Nicholas J Wareham
Seropositivity and higher immunoglobulin g antibody levels against cytomegalovirus are associated with mortality in the population-based European prospective investigation of cancer-norfolk cohort.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2013;56(10):1421-7.
2013: Parinya Chamnan; Kay-Tee Khaw; RK Simmons; Nicholas J Wareham; Simon J Griffin
Change in HbA1c over 3 years does not improve the prediction of cardiovascular disease over and above HbA1c measured at a single time point.
Diabetologia 2013;56(5):1004-11.
2013: R Golubic; Kay-Tee Khaw; Robert Luben; Nicholas J Wareham; Katrien Wijndaele; Ulf Ekelund; Søren Brage
Rate of weight gain predicts change in physical activity levels: a longitudinal analysis of the EPIC-Norfolk cohort.
International journal of obesity (2005) 2013;37(3):404-9.
2013: M den Hoed; Ulf Ekelund; A Grøntved; A D Hingorani; K Jameson; K-T Khaw; M Kivimaki; M Kumari; C Langenberg; J Luan; A A Sayer; Nicholas J Wareham; C Cooper; R J F Loos
Evaluation of common genetic variants identified by GWAS for early onset and morbid obesity in population-based samples.
International journal of obesity (2005) 2013;37(2):191-6.
2013: Ersen B Colkesen; Bart S Ferket; Harald T Jørstad; Ron J G Peters; Jan G P Tijssen; Nicholas J Wareham; S Matthijs Boekholdt; Kay-Tee Khaw
A comparative analysis of three widely used lipid management guidelines in the EPIC-Norfolk cohort.
European journal of preventive cardiology 2013;20(1):98-106.
2013: Anthony P Khawaja; Robert Luben; Justin C Sherwin; Nicholas J Wareham; Jennifer L Y Yip; David C Broadway; Michelle P Y Chan; Nichola Dalzell; David F Garway-Heath; Shabina Hayat; Kay-Tee Khaw; Paul J Foster
The EPIC-Norfolk Eye Study: rationale, methods and a cross-sectional analysis of visual impairment in a population-based cohort.
BMJ open 2013;3(3):.
2013: Anne M May; Petra H M Peeters; Nicholas J Wareham; Daniel R Barnes; Nita G Forouhi; Kay-Tee Khaw; Robert Luben; Stephen J Sharp
Prediction of measured weight from self-reported weight was not improved after stratification by body mass index.
Obesity (Silver Spring, Md.) 2013;21(1):E137-42.
2012: Deepti Gurdasani; G Kees Hovingh; Kay-Tee Khaw; Robert N Luben; Cristina Pomilla; Barbara Sjouke; Sotirios Tsimikas; Nicholas W J Wainwright; Nicholas J Wareham; S Matthijs Boekholdt; Manjinder S Sandhu
Lipoprotein(a) and risk of coronary, cerebrovascular, and peripheral artery disease: the EPIC-Norfolk prospective population study.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(12):3058-65.
2012: RK Simmons; Nicholas J Wareham; Kate M Williams; Justin B. Echouffo Tcheugui; Ann Louise Kinmonth; A Toby Prevost; Lincoln A Sargeant; Stephen J Sharp; Simon J Griffin
Screening for type 2 diabetes and population mortality over 10 years (ADDITION-Cambridge): a cluster-randomised controlled trial.
Lancet 2012;380(9855):1741-8.
2012: RK Simmons; Maureen van den Donk; Nicholas J Wareham; Knut Borch-Johnsen; M J Davies; Kamlesh Khunti; torsten lauritzen; G E H M Rutten; Annelli Sandbaek; S J Sharp; Simon J Griffin
Does early intensive multifactorial treatment reduce total cardiovascular burden in individuals with screen-detected diabetes? Findings from the ADDITION-Europe cluster-randomized trial.
Diabetic medicine : a journal of the British Diabetic Association 2012;29(11):e409-16.
2012: Nita G Forouhi; Kay-Tee Khaw; C Langenberg; R Luben; A P Rickard; Z Ye; Nicholas J Wareham
Circulating 25-hydroxyvitamin D concentration and the risk of type 2 diabetes: results from the European Prospective Investigation into Cancer (EPIC)-Norfolk cohort and updated meta-analysis of prospective studies.
Diabetologia 2012;55(8):2173-82.
2012: Karani S Vimaleswaran; Nicholas J Wareham; Lars Ängquist; Heiner Boeing; Nabila Bouatia-Naji; Edith J M Feskens; Rikke D Hansen; Claus Holst; Giovanna Masala; Karina Meidtner; Kim Overvad; Domenico Palli; Wim H M Saris; Thorkild I A Sørensen; Anne Tjønneland; Marianne U Jakobsen; Daphne L van der A; Ruth J F Loos
Association between FTO variant and change in body weight and its interaction with dietary factors: the DiOGenes study.
Obesity (Silver Spring, Md.) 2012;20(8):1669-74.
2012: Justin C Sherwin; Nicholas J Wareham; David Broadway; Nichola Dalzell; Shabina Hayat; Kay-Tee Khaw; Anthony P Khawaja; Robert Luben; Paul J Foster
Uncorrected refractive error in older British adults: the EPIC-Norfolk Eye Study.
The British journal of ophthalmology 2012;96(7):991-6.
2012: Parinya Chamnan; Kay-Tee Khaw; RK Simmons; Nicholas J Wareham; Simon J Griffin
Estimating the potential population impact of stepwise screening strategies for identifying and treating individuals at high risk of Type 2 diabetes: a modelling study.
Diabetic medicine : a journal of the British Diabetic Association 2012;29(7):893-904.
2012: M Rahman; RK Simmons; Nicholas J Wareham; S H Hennings; Simon J Griffin
Effect of screening for Type 2 diabetes on population-level self-rated health outcomes and measures of cardiovascular risk: 13-year follow-up of the Ely cohort.
Diabetic medicine : a journal of the British Diabetic Association 2012;29(7):886-92.
2012: M Rahman; RK Simmons; Nicholas J Wareham; S H Hennings; Simon J Griffin
How much does screening bring forward the diagnosis of type 2 diabetes and reduce complications? Twelve year follow-up of the Ely cohort.
Diabetologia 2012;55(6):1651-9.
2012: Cathy E Elks; Rebecca Hardy; Diana Kuh; Ruth J F Loos; Nicholas J Wareham; Andrew K Wills; Andrew Wong; Ken K Ong
Adult obesity susceptibility variants are associated with greater childhood weight gain and a faster tempo of growth: the 1946 British Birth Cohort Study.
The American journal of clinical nutrition 2012;95(5):1150-6.
2012: Adam Barker; Claudia Langenberg; Nicholas J Wareham
Genetic determinants of glucose homeostasis.
Best practice & research. Clinical endocrinology & metabolism 2012;26(2):159-70.
2012: Jajini S Varghese; Nicholas J Wareham; Ruth M L Warren; Carmel Apicella; Elizabeth J Atkinson; Norman F Boyd; Judith Brown; Fergus J Couch; Kamila Czene; Louise Eriksson; Per Hall; John L Hopper; Jean Leyland; Jingmei Li; Sara Lindström; Ruth J Loos; Robert N Luben; Lisa J Martin; Kyriaki Michailidou; Andrew D Paterson; Nazneen Rahman; Johanna Rommens; Christopher G Scott; Melissa C Southey; Jennifer Stone; Rulla M Tamimi; Deborah J Thompson; Clare Turnbull; Celine M Vachon; Douglas F Easton
Mammographic breast density and breast cancer: evidence of a shared genetic basis.
Cancer research 2012;72(6):1478-84.
2012: Judith S Brand; Mitch Dowsett; Elizabeth Folkerd; Robert N Luben; Yvonne T van der Schouw; Nicholas J Wareham; Kay-Tee Khaw
Testosterone, SHBG and differential white blood cell count in middle-aged and older men.
Maturitas 2012;71(3):274-8.
2012: H A Ward; Nicholas J Wareham; R Keogh; M Lentjes; Robert N Luben; Kay-Tee Khaw
Fibre intake in relation to serum total cholesterol levels and CHD risk: a comparison of dietary assessment methods.
European journal of clinical nutrition 2012;66(3):296-304.
2012: Cathy E Elks; Ruth J F Loos; Stephen J Sharp; Nicholas J Wareham; Jing Hua Zhao; Marcel den Hoed; Ken K Ong
Variability in the heritability of body mass index: a systematic review and meta-regression.
Frontiers in endocrinology 2012;3():29.
2011: Maureen van den Donk; Nicholas J Wareham; Annelli Sandbaek; RK Simmons; K Borch-Johnsen; M J Davies; Simon J Griffin; Kamlesh Khunti; torsten lauritzen; G E H M Rutten
Screening for type 2 diabetes. Lessons from the ADDITION-Europe study.
Diabetic medicine : a journal of the British Diabetic Association 2011;28(11):1416-24.
2011: Roman Pfister; Veikko Salomaa; Naveed Sattar; Stephen Sharp; Inês Barroso; Kay-Tee Khaw; Claudia Langenberg; Robert Luben; Aline Meirhaeghe; Paul Welsh; Nicholas J Wareham
Mendelian randomization study of B-type natriuretic peptide and type 2 diabetes: evidence of causal association from population studies.
PLoS medicine 2011;8(10):e1001112.
2011: Paul J Foster; David F Garway-Heath; Shabina Hayat; David C Broadway; Nichola Dalzell; Robert Luben; Nicholas J Wareham; Jennifer L Y Yip; Kay-Tee Khaw
Intraocular pressure and corneal biomechanics in an adult British population: the EPIC-Norfolk eye study.
Investigative ophthalmology & visual science 2011;52(11):8179-85.
2011: Jennifer L Y Yip; Amit Bhaniani; David C Broadway; Nichola Dalzell; David F Garway-Heath; Shabina Hayat; Kay-Tee Khaw; Pak Sang Lee; Robert Luben; Nicholas J Wareham; Paul J Foster
Physical activity and ocular perfusion pressure: the EPIC-Norfolk eye study.
Investigative ophthalmology & visual science 2011;52(11):8186-92.
2011: R Pfister; Nicholas J Wareham; R Luben; D Barnes; M Bochud; Nita G Forouhi; Kay-Tee Khaw; C Langenberg
No evidence for a causal link between uric acid and type 2 diabetes: a Mendelian randomisation approach.
Diabetologia 2011;54(10):2561-9.
2011: R Pfister; Nicholas J Wareham; D Barnes; Kay-Tee Khaw; Robert N Luben; C Langenberg
Individual and cumulative effect of type 2 diabetes genetic susceptibility variants on risk of coronary heart disease.
Diabetologia 2011;54(9):2283-7.
2011: Paul J R Banim; Heerajnarain Bulluck; Kay-Tee Khaw; Robert N Luben; Stephen J Sharp; Nicholas J Wareham; Andrew R Hart
The aetiology of symptomatic gallstones quantification of the effects of obesity, alcohol and serum lipids on risk. Epidemiological and biomarker data from a UK prospective cohort study (EPIC-Norfolk).
European journal of gastroenterology & hepatology 2011;23(8):733-40.
2011: R Pfister; S J Sharp; Kay-Tee Khaw; R Luben; Nicholas J Wareham
No evidence of an increased mortality risk associated with low levels of glycated haemoglobin in a non-diabetic UK population.
Diabetologia 2011;54(8):2025-32.
2011: Simon J Griffin; Kamlesh Khunti; Knut Borch-Johnsen; Melanie J Davies; Guy E H M Rutten; Annelli Sandbaek; Stephen J Sharp; RK Simmons; Maureen van den Donk; Nicholas J Wareham; torsten lauritzen
Effect of early intensive multifactorial therapy on 5-year cardiovascular outcomes in individuals with type 2 diabetes detected by screening (ADDITION-Europe): a cluster-randomised trial.
Lancet 2011;378(9786):156-67.
2011: Nicholas J Wareham; Simon J Griffin
Risk scores for predicting type 2 diabetes: comparing axes and spades.
Diabetologia 2011;54(5):994-5.
2011: Judith S Brand; Nicholas J Wareham; Mitch Dowsett; Elizabeth Folkerd; Yvonne T van der Schouw; Robert N Luben; Kay-Tee Khaw
Associations of endogenous testosterone and SHBG with glycated haemoglobin in middle-aged and older men.
Clinical endocrinology 2011;74(5):572-8.
2011: Lysette N Broekhuizen; S Matthijs Boekholdt; Benoit J Arsenault; Jean-Pierre Despres; Erik S G Stroes; JJ Kastelein; Kay-Tee Khaw; Nicholas J Wareham
Physical activity, metabolic syndrome, and coronary risk: the EPIC-Norfolk prospective population study.
European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 2011;18(2):209-17.
2011: Shengxu Li; J H Zhao; Jian'an Luan; C Langenberg; Robert N Luben; Kay-Tee Khaw; Nicholas J Wareham; Ruth J F Loos
Genetic predisposition to obesity leads to increased risk of type 2 diabetes.
Diabetologia 2011;54(4):776-82.
2011: Anders Grøntved; Lars B Andersen; Paul W Franks; Bas Verhage; Nicholas J Wareham; Ulf Ekelund; Ruth J F Loos; Søren Brage
NOS3 variants, physical activity, and blood pressure in the European Youth Heart Study.
American journal of hypertension 2011;24(4):444-50.
2011: Tuomas O Kilpeläinen; Marcel den Hoed; Ken K Ong; Anders Grøntved; Soren Brage; Karen Jameson; Cyrus Cooper; Kay-Tee Khaw; Ulf Ekelund; Nicholas J Wareham; Ruth J F Loos
Obesity-susceptibility loci have a limited influence on birth weight: a meta-analysis of up to 28,219 individuals.
The American journal of clinical nutrition 2011;93(4):851-60.
2011: Parinya Chamnan; RK Simmons; Nita G Forouhi; Robert N Luben; Kay-Tee Khaw; Nicholas J Wareham; Simon J Griffin
Incidence of type 2 diabetes using proposed HbA1c diagnostic criteria in the european prospective investigation of cancer-norfolk cohort: implications for preventive strategies.
Diabetes care 2011;34(4):950-6.
2011: J Y Park; P N Mitrou; R H Keogh; Robert N Luben; Nicholas J Wareham; Kay-Tee Khaw
Effects of body size and sociodemographic characteristics on differences between self-reported and measured anthropometric data in middle-aged men and women: the EPIC-Norfolk study.
European journal of clinical nutrition 2011;65(3):357-67.
2011: Heather Ward; Nicholas J Wareham; Robert N Luben; Kay-Tee Khaw
CHD risk in relation to alcohol intake from categorical and open-ended dietary instruments.
Public health nutrition 2011;14(3):402-9.
2011: RK Simmons; M Rahman; Rupert W Jakes; M F Yuyun; A R Niggebrugge; S H Hennings; D R R Williams; Nicholas J Wareham; Simon J Griffin
Effect of population screening for type 2 diabetes on mortality: long-term follow-up of the Ely cohort.
Diabetologia 2011;54(2):312-9.
2011: Parinya Chamnan; RK Simmons; R Jackson; Kay-Tee Khaw; Nicholas J Wareham; Simon J Griffin
Non-diabetic hyperglycaemia and cardiovascular risk: moving beyond categorisation to individual interpretation of absolute risk.
Diabetologia 2011;54(2):291-9.
2011: Felix K Assah; Ulf Ekelund; Søren Brage; Antony Wright; Jean-Claude Mbanya; Nicholas J Wareham
Accuracy and validity of a combined heart rate and motion sensor for the measurement of free-living physical activity energy expenditure in adults in Cameroon.
International journal of epidemiology 2011;40(1):112-20.
2011: Jamal S Rana; Benoit J Arsenault; Jean-Pierre Després; Mélanie Côté; Philippa J Talmud; Ewa Ninio; J Wouter Jukema; Nicholas J Wareham; John J P Kastelein; Kay-Tee Khaw; S Matthijs Boekholdt
Inflammatory biomarkers, physical activity, waist circumference, and risk of future coronary heart disease in healthy men and women.
European heart journal 2011;32(3):336-44.
2011: Dora Romaguera; Annika Steffen; Anne Tjønneland; Daphne L van der A; Nicholas J Wareham; Lars Ängquist; Heiner Boeing; Huaidong Du; Edith J M Feskens; Nita G Forouhi; Jytte Halkjaer; Marianne U Jakobsen; Giovanna Masala; Kim Overvad; Domenico Palli; Elio Riboli; Thorkild I Sørensen
Food composition of the diet in relation to changes in waist circumference adjusted for body mass index.
PloS one 2011;6(8):e23384.
2011: Vincent T van Hees; Nicholas J Wareham; Antony Wright; Les Bluck; Søren Brage; Michael Catt; Kong Y Chen; Ulf Ekelund; Anna Gradmark; Marie Löf; Jeremy Pomeroy; Frida Renström; Paul W Franks
Estimation of daily energy expenditure in pregnant and non-pregnant women using a wrist-worn tri-axial accelerometer.
PloS one 2011;6(7):e22922.
2011: Hannah S Mumby; Stephen J Sharp; Nicholas J Wareham; Cathy E Elks; Kay-Tee Khaw; Shengxu Li; Ruth J F Loos; Robert N Luben; Ken K Ong
Mendelian Randomisation Study of Childhood BMI and Early Menarche.
Journal of obesity 2011;2011():180729.
2011: Charlie E Foster; Jenna R Panter; Nicholas J Wareham
Assessing the impact of road traffic on cycling for leisure and cycling to work.
The international journal of behavioral nutrition and physical activity 2011;8():61.
2011: Katrien Wijndaele; Hervé Besson; Amit Bhaniani; Søren Brage; Kay-Tee Khaw; Robert Luben; Stephen J Sharp; Nicholas J Wareham; Ulf Ekelund
Television viewing and incident cardiovascular disease: prospective associations and mediation analysis in the EPIC Norfolk Study.
PloS one 2011;6(5):e20058.
2011: Ken K Ong; Cathy E Elks; Andrew Wills; Andrew Wong; Nicholas J Wareham; Ruth J F Loos; Diana Kuh; Rebecca Hardy
Associations between the pubertal timing-related variant in LIN28B and BMI vary across the life course.
The Journal of clinical endocrinology and metabolism 2011;96(1):E125-9.
2010: Suthesh Sivapalaratnam; S Matthijs Boekholdt; Mieke D Trip; Manjinder S Sandhu; Robert Luben; John J P Kastelein; Nicholas J Wareham; Kay-Tee Khaw
Family history of premature coronary heart disease and risk prediction in the EPIC-Norfolk prospective population study.
Heart (British Cardiac Society) 2010;96(24):1985-9.
2010: Benoit J Arsenault; Jean-Pierre Després; Erik S G Stroes; Nicholas J Wareham; John J P Kastelein; Kay-Tee Khaw; S Matthijs Boekholdt
Lipid assessment, metabolic syndrome and coronary heart disease risk.
European journal of clinical investigation 2010;40(12):1081-93.
2010: Pinal S Patel; Stephen J Sharp; Eugene Jansen; Robert N Luben; Kay-Tee Khaw; Nicholas J Wareham; Nita G Forouhi
Fatty acids measured in plasma and erythrocyte-membrane phospholipids and derived by food-frequency questionnaire and the risk of new-onset type 2 diabetes: a pilot study in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk cohort.
The American journal of clinical nutrition 2010;92(5):1214-22.
2010: Melissa C Smart-Halajko; Marius R Robciuc; Jackie A Cooper; Matti Jauhiainen; Meena Kumari; Mika Kivimaki; Kay-Tee Khaw; S Matthijs Boekholdt; Nicholas J Wareham; Tom R Gaunt; Ian N M Day; Peter S Braund; Christopher P Nelson; Alistair Hall; Nilesh J Samani; Steve E Humphries; Christian Ehnholm; Philippa J Talmud
The relationship between plasma angiopoietin-like protein 4 levels, angiopoietin-like protein 4 genotype, and coronary heart disease risk.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(11):2277-82.
2010: Kirsten Corder; Søren Brage; Antony Wright; Ambady Ramachandran; Chamukuttan Snehalatha; Annasami Yamuna; Nicholas J Wareham; Ulf Ekelund
Physical activity energy expenditure of adolescents in India.
Obesity (Silver Spring, Md.) 2010;18(11):2212-9.
2010: Karani S Vimaleswaran; Paul W Franks; Søren Brage; Anders Grontved; Nicholas J Wareham; Ulf Ekelund; Ruth J F Loos
Lack of association between PCK1 polymorphisms and obesity, physical activity, and fitness in European Youth Heart Study (EYHS).
Obesity (Silver Spring, Md.) 2010;18(10):1975-80.
2010: Jamal S Rana; Maartje E Visser; Benoit J Arsenault; Jean-Pierre Després; Erik S G Stroes; John J P Kastelein; Nicholas J Wareham; S Matthijs Boekholdt; Kay-Tee Khaw
Metabolic dyslipidemia and risk of future coronary heart disease in apparently healthy men and women: the EPIC-Norfolk prospective population study.
International journal of cardiology 2010;143(3):399-404.
2010: L A Sargeant; RK Simmons; R S Barling; R Butler; K M Williams; A T Prevost; A L Kinmonth; Nicholas J Wareham; Simon J Griffin
Who attends a UK diabetes screening programme? Findings from the ADDITION-Cambridge study.
Diabetic medicine : a journal of the British Diabetic Association 2010;27(9):995-1003.
2010: Alireza Moayyeri; Hervé Besson; Robert N Luben; Nicholas J Wareham; Kay-Tee Khaw
The association between physical activity in different domains of life and risk of osteoporotic fractures.
Bone 2010;47(3):693-700.
2010: Menno Vergeer; S Matthijs Boekholdt; Manjinder S Sandhu; Sally L Ricketts; Nicholas J Wareham; Morris J Brown; Ulf de Faire; Karin Leander; Bruna Gigante; Maryam Kavousi; Albert Hofman; Andre G Uitterlinden; Cornelia M van Duijn; Jacqueline C M Witteman; J Wouter Jukema; Eric E Schadt; Ellen van der Schoot; John J P Kastelein; Kay-Tee Khaw; Robin P F Dullaart; Arie Van Tol; Mieke D Trip; Geesje M Dallinga-Thie
Genetic variation at the phospholipid transfer protein locus affects its activity and high-density lipoprotein size and is a novel marker of cardiovascular disease susceptibility.
Circulation 2010;122(5):470-7.
2010: Parinya Chamnan; RK Simmons; Hiroyuki Hori; Stephen Sharp; Kay-Tee Khaw; Nicholas J Wareham; Simon J Griffin
A simple risk score using routine data for predicting cardiovascular disease in primary care.
The British journal of general practice : the journal of the Royal College of General Practitioners 2010;60(577):e327-34.
2010: Emanuella De Lucia Rolfe; Ruth J F Loos; Céline Druet; Ronald P Stolk; Ulf Ekelund; Simon J Griffin; Nita G Forouhi; Nicholas J Wareham; Ken K Ong
Association between birth weight and visceral fat in adults.
The American journal of clinical nutrition 2010;92(2):347-52.
2010: Menno Vergeer; Danny M Cohn; S Matthijs Boekholdt; Manjinder S Sandhu; Hester M Prins; Sally L Ricketts; Nicholas J Wareham; John J P Kastelein; Kay-Tee Khaw; Pieter W Kamphuisen; Geesje M Dallinga-Thie
Lack of association between common genetic variation in endothelial lipase (LIPG) and the risk for CAD and DVT.
Atherosclerosis 2010;211(2):558-64.
2010: Paul G Surtees; Nicholas W J Wainwright; Robert Luben; Nicholas J Wareham; Sheila A Bingham; Kay-Tee Khaw
Mastery is associated with cardiovascular disease mortality in men and women at apparently low risk.
Health psychology : official journal of the Division of Health Psychology, American Psychological Association 2010;29(4):412-20.
2010: Nicholas J Wareham; Roman Pfister
Diabetes: glycated hemoglobin is a marker of diabetes and CVD risk.
Nature reviews. Cardiology 2010;7(7):367-8.
2010: Diederik F van Wijk; Sander I van Leuven; Manjinder S Sandhu; Michael W T Tanck; Barbara A Hutten; Nicholas J Wareham; John J P Kastelein; Erik S G Stroes; Kay-Tee Khaw; S Matthijs Boekholdt
Chemokine ligand 2 genetic variants, serum monocyte chemoattractant protein-1 levels, and the risk of coronary artery disease.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(7):1460-6.
2010: K S Vimaleswaran; J H Zhao; N W Wainwright; P G Surtees; Nicholas J Wareham; Ruth J F Loos
Association between serotonin 5-HT-2C receptor gene (HTR2C) polymorphisms and obesity- and mental health-related phenotypes in a large population-based cohort.
International journal of obesity (2005) 2010;34(6):1028-33.
2010: Benoit J Arsenault; Isabelle Lemieux; Jean-Pierre Després; Nicholas J Wareham; Erik S G Stroes; John J P Kastelein; Kay-Tee Khaw; S Matthijs Boekholdt
Comparison between gradient gel electrophoresis and nuclear magnetic resonance spectroscopy in estimating coronary heart disease risk associated with LDL and HDL particle size.
Clinical chemistry 2010;56(5):789-98.
2010: F M Finucane; S J Sharp; L R Purslow; K Horton; J Horton; David B Savage; Søren Brage; H Besson; E De Lucia Rolfe; A Sleigh; H J Martin; A Aihie Sayer; C Cooper; Ulf Ekelund; Simon J Griffin; Nicholas J Wareham
The effects of aerobic exercise on metabolic risk, insulin sensitivity and intrahepatic lipid in healthy older people from the Hertfordshire Cohort Study: a randomised controlled trial.
Diabetologia 2010;53(4):624-31.
2010: S Matthijs Boekholdt; Silvia M Titan; Wilmar M Wiersinga; Krishna Chatterjee; Dick C G Basart; Robert Luben; Nicholas J Wareham; Kay-Tee Khaw
Initial thyroid status and cardiovascular risk factors: the EPIC-Norfolk prospective population study.
Clinical endocrinology 2010;72(3):404-10.
2010: A G Holleboom; Jan Albert Kuivenhoven; M Vergeer; G Kees Hovingh; Joram N I van Miert; Nicholas J Wareham; J J P Kastelein; Kay-Tee Khaw; S Matthijs Boekholdt
Plasma levels of lecithin:cholesterol acyltransferase and risk of future coronary artery disease in apparently healthy men and women: a prospective case-control analysis nested in the EPIC-Norfolk population study.
Journal of lipid research 2010;51(2):416-21.
2010: Effrossyni Gkrania-Klotsas; Zheng Ye; Andrew J Cooper; Stephen J Sharp; Robert Luben; Mary L Biggs; Liang-Kung Chen; Kuppan Gokulakrishnan; Markolf Hanefeld; Erik Ingelsson; Wen-An Lai; Shih-Yi Lin; Lars Lind; Vitool Lohsoonthorn; Viswanathan Mohan; Antonio Muscari; Goran Nilsson; John Ohrvik; Jiang Chao Qiang; Nancy Swords Jenny; Koji Tamakoshi; Theodora Temelkova-Kurktschiev; Ya-Yu Wang; Chittaranjan Sakerlal Yajnik; Marco Zoli; Kay-Tee Khaw; Nita G Forouhi; Nicholas J Wareham; Claudia Langenberg
Differential white blood cell count and type 2 diabetes: systematic review and meta-analysis of cross-sectional and prospective studies.
PloS one 2010;5(10):e13405.
2010: Shengxu Li; Jing Hua Zhao; Jian'an Luan; Ulf Ekelund; Robert N Luben; Kay-Tee Khaw; Nicholas J Wareham; Ruth J F Loos
Physical activity attenuates the genetic predisposition to obesity in 20,000 men and women from EPIC-Norfolk prospective population study.
PLoS medicine 2010;7(8):.
2010: Dora Romaguera; Lars Angquist; Huaidong Du; Marianne Uhre Jakobsen; Nita G Forouhi; Jytte Halkjaer; Edith J M Feskens; Daphne L van der A; Giovanna Masala; Annika Steffen; Domenico Palli; Nicholas J Wareham; Kim Overvad; Anne Tjønneland; Heiner Boeing; Elio Riboli; Thorkild I A Sørensen
Dietary determinants of changes in waist circumference adjusted for body mass index - a proxy measure of visceral adiposity.
PloS one 2010;5(7):e11588.
2010: Hervé Besson; Ceryl A Harwood; Ulf Ekelund; Francis M Finucane; Christopher J McDermott; Pamela J Shaw; Nicholas J Wareham
Validation of the historical adulthood physical activity questionnaire (HAPAQ) against objective measurements of physical activity.
The international journal of behavioral nutrition and physical activity 2010;7():54.
2010: Parinya Chamnan; RK Simmons; Kay-Tee Khaw; Nicholas J Wareham; Simon J Griffin
Estimating the population impact of screening strategies for identifying and treating people at high risk of cardiovascular disease: modelling study.
BMJ (Clinical research ed.) 2010;340():c1693.
2010: Hervé Besson; Søren Brage; Rupert W Jakes; Ulf Ekelund; Nicholas J Wareham
Estimating physical activity energy expenditure, sedentary time, and physical activity intensity by self-report in adults.
The American journal of clinical nutrition 2010;91(1):106-14.
2010: Shengxu Li; Jing Hua Zhao; Jian'an Luan; Robert N Luben; Sheila A Rodwell; Kay-Tee Khaw; Ken K Ong; Nicholas J Wareham; Ruth J F Loos
Cumulative effects and predictive value of common obesity-susceptibility variants identified by genome-wide association studies.
The American journal of clinical nutrition 2010;91(1):184-90.
2009: Nicholas J Wareham
Epidemiology of type 2 diabetes.
Endocrinología y nutrición : órgano de la Sociedad Española de Endocrinología y Nutrición 2009;56 Suppl 4():60-2.
2009: Nita G Forouhi; Stephen J Sharp; Huaidong Du; Daphne L van der A; Jytte Halkjaer; Matthias B Schulze; Anne Tjønneland; Kim Overvad; Marianne Uhre Jakobsen; Heiner Boeing; Brian Buijsse; Domenico Palli; Giovanna Masala; Edith J M Feskens; Thorkild I A Sørensen; Nicholas J Wareham
Dietary fat intake and subsequent weight change in adults: results from the European Prospective Investigation into Cancer and Nutrition cohorts.
The American journal of clinical nutrition 2009;90(6):1632-41.
2009: Jin Young Park; Panagiota N Mitrou; Christina C Dahm; Robert N Luben; Nicholas J Wareham; Kay-Tee Khaw; Sheila A Rodwell
Baseline alcohol consumption, type of alcoholic beverage and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition-Norfolk study.
Cancer epidemiology 2009;33(5):347-54.
2009: F M Finucane; Jian'an Luan; Nicholas J Wareham; S J Sharp; S O'Rahilly; B Balkau; A Flyvbjerg; M Walker; K Højlund; J J Nolan; David B Savage
Correlation of the leptin:adiponectin ratio with measures of insulin resistance in non-diabetic individuals.
Diabetologia 2009;52(11):2345-9.
2009: Parinya Chamnan; RK Simmons; S J Sharp; Simon J Griffin; Nicholas J Wareham
Cardiovascular risk assessment scores for people with diabetes: a systematic review.
Diabetologia 2009;52(10):2001-14.
2009: Pinal S Patel; Stephen J Sharp; Robert N Luben; Kay-Tee Khaw; Sheila A Bingham; Nicholas J Wareham; Nita G Forouhi
Association between type of dietary fish and seafood intake and the risk of incident type 2 diabetes: the European prospective investigation of cancer (EPIC)-Norfolk cohort study.
Diabetes care 2009;32(10):1857-63.
2009: Tuomas Kilpeläinen; Sheila A Bingham; Kay-Tee Khaw; Nicholas J Wareham; Ruth J F Loos
Association of variants in the PCSK1 gene with obesity in the EPIC-Norfolk study.
Human molecular genetics 2009;18(18):3496-501.
2009: Heather Ward; Panagiota N Mitrou; Richard Bowman; Robert Luben; Nicholas J Wareham; Kay-Tee Khaw; Sheila Bingham
APOE genotype, lipids, and coronary heart disease risk: a prospective population study.
Archives of internal medicine 2009;169(15):1424-9.
2009: Anne Q Reuwer; Marcel Th B Twickler; Barbara A Hutten; Frederique W Molema; Nicholas J Wareham; Geesje M Dallinga-Thie; Roman Bogorad; Vincent Goffin; Mijke Smink-Bol; John J P Kastelein; S Matthijs Boekholdt; Kay-Tee Khaw
Prolactin levels and the risk of future coronary artery disease in apparently healthy men and women.
Circulation. Cardiovascular genetics 2009;2(4):389-95.
2009: Karani S Vimaleswaran; Shengxu Li; Jing Hua Zhao; Jian'an Luan; Sheila A Bingham; Kay-Tee Khaw; Ulf Ekelund; Nicholas J Wareham; Ruth J F Loos
Physical activity attenuates the body mass index-increasing influence of genetic variation in the FTO gene.
The American journal of clinical nutrition 2009;90(2):425-8.
2009: Hendrik J F Helmerhorst; Katrien Wijndaele; Søren Brage; Nicholas J Wareham; Ulf Ekelund
Objectively measured sedentary time may predict insulin resistance independent of moderate- and vigorous-intensity physical activity.
Diabetes 2009;58(8):1776-9.
2009: C Langenberg; L Pascoe; A Mari; A Tura; M Laakso; T M Frayling; I Barroso; Ruth J F Loos; Nicholas J Wareham; M Walker
Common genetic variation in the melatonin receptor 1B gene (MTNR1B) is associated with decreased early-phase insulin response.
Diabetologia 2009;52(8):1537-42.
2009: Alireza Moayyeri; Stephen Kaptoge; Nichola Dalzell; Robert N Luben; Nicholas J Wareham; Sheila Bingham; Jonathan Reeve; Kay-Tee Khaw
The effect of including quantitative heel ultrasound in models for estimation of 10-year absolute risk of fracture.
Bone 2009;45(2):180-4.
2009: Felix K Assah; Ulf Ekelund; Søren Brage; Kirsten Corder; Antony Wright; Jean-Claude Mbanya; Nicholas J Wareham
Predicting physical activity energy expenditure using accelerometry in adults from sub-Sahara Africa.
Obesity (Silver Spring, Md.) 2009;17(8):1588-95.
2009: Karani S Vimaleswaran; Paul W Franks; Søren Brage; Luis B Sardinha; Lars B Andersen; Nicholas J Wareham; Ulf Ekelund; Ruth J F Loos
Absence of association between the INSIG2 gene polymorphism (rs7566605) and obesity in the European Youth Heart Study (EYHS).
Obesity (Silver Spring, Md.) 2009;17(7):1453-7.
2009: C C Lee; A I Adler; Manjinder S Sandhu; S J Sharp; Nita G Forouhi; S Erqou; R Luben; Sheila Bingham; Kay-Tee Khaw; Nicholas J Wareham
Association of C-reactive protein with type 2 diabetes: prospective analysis and meta-analysis.
Diabetologia 2009;52(6):1040-7.
2009: Ulf Ekelund; Søren Brage; Simon J Griffin; Nicholas J Wareham
Objectively measured moderate- and vigorous-intensity physical activity but not sedentary time predicts insulin resistance in high-risk individuals.
Diabetes care 2009;32(6):1081-6.
2009: Paul G Surtees; Nicholas W J Wainwright; Richard Bowman; Robert N Luben; Nicholas J Wareham; Kay-Tee Khaw; Sheila A Bingham
No association between APOE and major depressive disorder in a community sample of 17,507 adults.
Journal of psychiatric research 2009;43(9):843-7.
2009: R Bowman; A M C P Joosen; Ailsa A Welch; Robert N Luben; Kay-Tee Khaw; Nicholas J Wareham; Sheila A Bingham
Factor VII, blood lipids and fat intake: gene-nutrient interaction and risk of coronary heart disease with the factor VII R353Q polymorphism.
European journal of clinical nutrition 2009;63(6):771-7.
2009: Alireza Moayyeri; Sheila A Bingham; Robert N Luben; Nicholas J Wareham; Kay-Tee Khaw
Respiratory function as a marker of bone health and fracture risk in an older population.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2009;24(5):956-63.
2009: R M Steele; F M Finucane; RK Simmons; Simon J Griffin; Nicholas J Wareham; Ulf Ekelund
Altered respiratory function is associated with increased metabolic risk, independently of adiposity, fitness and physical activity.
Diabetic medicine : a journal of the British Diabetic Association 2009;26(4):362-9.
2009: E C Brito; Karani Santhanakrishnan Vimaleswaran; Søren Brage; L B Andersen; L B Sardinha; Nicholas J Wareham; Ulf Ekelund; Ruth J F Loos; Paul W Franks
PPARGC1A sequence variation and cardiovascular risk-factor levels: a study of the main genetic effects and gene x environment interactions in children from the European Youth Heart Study.
Diabetologia 2009;52(4):609-13.
2009: E McFadden; Robert Luben; Sheila Bingham; Nicholas J Wareham; Ann Louise Kinmonth; Kay-Tee Khaw
Self-rated health does not explain the socioeconomic differential in mortality: a prospective study in the EPIC-Norfolk cohort.
Journal of epidemiology and community health 2009;63(4):329-31.
2009: Felix K Assah; Ulf Ekelund; Søren Brage; Jean-Claude Mbanya; Nicholas J Wareham
Free-living physical activity energy expenditure is strongly related to glucose intolerance in Cameroonian adults independently of obesity.
Diabetes care 2009;32(2):367-9.
2009: Karim El Harchaoui; Benoit J Arsenault; Remco Franssen; Jean-Pierre Després; G Kees Hovingh; Erik S G Stroes; James D Otvos; Nicholas J Wareham; John J P Kastelein; Kay-Tee Khaw; S Matthijs Boekholdt
High-density lipoprotein particle size and concentration and coronary risk.
Annals of internal medicine 2009;150(2):84-93.
2009: Jian'an Luan; Berit Kerner; Jing-Hua Zhao; Ruth Jf Loos; Stephen J Sharp; Bengt Muthén; Nicholas J Wareham
A multilevel linear mixed model of the association between candidate genes and weight and body mass index using the Framingham longitudinal family data.
BMC proceedings 2009;3 Suppl 7():S115.
2009: Rakesh S Birjmohun; Menno Vergeer; Erik S G Stroes; Manjinder S Sandhu; Sally L Ricketts; Michael W T Tanck; Nicholas J Wareham; J Wouter Jukema; John J P Kastelein; Kay-Tee Khaw; S Matthijs Boekholdt
Both paraoxonase-1 genotype and activity do not predict the risk of future coronary artery disease; the EPIC-Norfolk Prospective Population Study.
PloS one 2009;4(8):e6809.
2009: Francis M Finucane; Jessica Horton; Lisa R Purslow; David B Savage; Søren Brage; Hervé Besson; Kenneth Horton; Ema De Lucia Rolfe; Alison Sleigh; Stephen J Sharp; Helen J Martin; Avan Aihie Sayer; Cyrus Cooper; Ulf Ekelund; Simon J Griffin; Nicholas J Wareham
Randomized controlled trial of the efficacy of aerobic exercise in reducing metabolic risk in healthy older people: The Hertfordshire Physical Activity Trial.
BMC endocrine disorders 2009;9():15.
2009: David Bruce Ogilvie; Peter Craig; Simon Griffin; Sally Macintyre; Nicholas J Wareham
A translational framework for public health research.
BMC public health 2009;9():116.
2009: Alireza Moayyeri; Stephen Kaptoge; Robert N Luben; Nicholas J Wareham; Sheila Bingham; Jonathan Reeve; Kay-Tee Khaw
Estimation of absolute fracture risk among middle-aged and older men and women: the EPIC-Norfolk population cohort study.
European journal of epidemiology 2009;24(5):259-66.
2009: E McFadden; Robert Luben; Sheila Bingham; Nicholas J Wareham; Ann Louise Kinmonth; Kay-Tee Khaw
Does the association between self-rated health and mortality vary by social class?
Social science & medicine (1982) 2009;68(2):275-80.
2008: Nicholas J Wareham; Kirsten Corder; Esther M F van Sluijs
Decrease in activity from childhood to adolescence: potential causes and consequences.
American journal of preventive medicine 2008;35(6):604-5.
2008: Philippa J Talmud; Melissa Smart; Edward Presswood; Jackie A Cooper; Viviane Nicaud; Fotios Drenos; Jutta Palmen; Michael G Marmot; S Matthijs Boekholdt; Nicholas J Wareham; Kay-Tee Khaw; Meena Kumari; Steve E Humphries
ANGPTL4 E40K and T266M: effects on plasma triglyceride and HDL levels, postprandial responses, and CHD risk.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(12):2319-25.
2008: Hervé Besson; Ulf Ekelund; Søren Brage; Robert Luben; Sheila Bingham; Kay-Tee Khaw; Nicholas J Wareham
Relationship between subdomains of total physical activity and mortality.
Medicine and science in sports and exercise 2008;40(11):1909-15.
2008: Inês Barroso; Jian'an Luan; Eleanor Wheeler; Pamela Whittaker; Jon Wasson; Eleftheria Zeggini; Michael N Weedon; Sarah Hunt; Ranganath Venkatesh; Timothy M Frayling; Marcos Delgado; Rosalind J Neuman; Jinghua Zhao; Richard Sherva; Benjamin Glaser; Mark Walker; Graham A Hitman; Mark I McCarthy; Andrew T Hattersley; M Alan Permutt; Nicholas J Wareham; Panos Deloukas
Population-specific risk of type 2 diabetes conferred by HNF4A P2 promoter variants: a lesson for replication studies.
Diabetes 2008;57(11):3161-5.
2008: Jing Wang; Robert Luben; Kay-Tee Khaw; Sheila Bingham; Nicholas J Wareham; Nita G Forouhi
Dietary energy density predicts the risk of incident type 2 diabetes: the European Prospective Investigation of Cancer (EPIC)-Norfolk Study.
Diabetes care 2008;31(11):2120-5.
2008: Chee-Tin Christine Lee; Amanda I Adler; Nita G Forouhi; Robert Luben; Ailsa Welch; Kay-Tee Khaw; Sheila Bingham; Nicholas J Wareham
Cross-sectional association between fish consumption and albuminuria: the European Prospective Investigation of Cancer-Norfolk Study.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2008;52(5):876-86.
2008: Paul G Surtees; Nicholas W J Wainwright; S Matthijs Boekholdt; Robert N Luben; Nicholas J Wareham; Kay-Tee Khaw
Major depression, C-reactive protein, and incident ischemic heart disease in healthy men and women.
Psychosomatic medicine 2008;70(8):850-5.
2008: Nita G Forouhi; Jian'an Luan; Andrew Cooper; Barbara J Boucher; Nicholas J Wareham
Baseline serum 25-hydroxy vitamin d is predictive of future glycemic status and insulin resistance: the Medical Research Council Ely Prospective Study 1990-2000.
Diabetes 2008;57(10):2619-25.
2008: Karani Santhanakrishnan Vimaleswaran; Jian'an Luan; Gitte Andersen; Y Li Muller; Eleanor Wheeler; Ema C Brito; Stephen O'Rahilly; Oluf Pedersen; Leslie J Baier; William C Knowler; Inês Barroso; Nicholas J Wareham; Ruth J F Loos; Paul W Franks
The Gly482Ser genotype at the PPARGC1A gene and elevated blood pressure: a meta-analysis involving 13,949 individuals.
Journal of applied physiology (Bethesda, Md. : 1985) 2008;105(4):1352-8.
2008: Ulf Ekelund; Søren Brage; Herve Besson; Stephen Sharp; Nicholas J Wareham
Time spent being sedentary and weight gain in healthy adults: reverse or bidirectional causality?
The American journal of clinical nutrition 2008;88(3):612-7.
2008: Kirsten Corder; Ulf Ekelund; Rebekah M Steele; Nicholas J Wareham; Søren Brage
Assessment of physical activity in youth.
Journal of applied physiology (Bethesda, Md. : 1985) 2008;105(3):977-87.
2008: Katherine A Fawcett; Neil Grimsey; Ruth J F Loos; Eleanor Wheeler; Allan Daly; Maria A Soos; Robert K Semple; Holly Syddall; Cyrus Cooper; Symeon Siniossoglou; Stephen O'Rahilly; Nicholas J Wareham; Inês Barroso
Evaluating the role of LPIN1 variation in insulin resistance, body weight, and human lipodystrophy in U.K. Populations.
Diabetes 2008;57(9):2527-33.
2008: Stephen Colagiuri; Knut Borch-Johnsen; Nicholas J Wareham
Back to the future--do IGT and IFG have value as clinical entities?
Diabetes research and clinical practice 2008;81(2):131-3.
2008: N Kurokawa; E H Young; Y Oka; H Satoh; Nicholas J Wareham; Manjinder S Sandhu; R J F Loos
The ADRB3 Trp64Arg variant and BMI: a meta-analysis of 44 833 individuals.
International journal of obesity (2005) 2008;32(8):1240-9.
2008: F K Assah; Søren Brage; Ulf Ekelund; Nicholas J Wareham
The association of intensity and overall level of physical activity energy expenditure with a marker of insulin resistance.
Diabetologia 2008;51(8):1399-407.
2008: Anne-Helen Harding; Nicholas J Wareham; Sheila A Bingham; KayTee Khaw; Robert Luben; Ailsa Welch; Nita G Forouhi
Plasma vitamin C level, fruit and vegetable consumption, and the risk of new-onset type 2 diabetes mellitus: the European prospective investigation of cancer--Norfolk prospective study.
Archives of internal medicine 2008;168(14):1493-9.
2008: Rebekah M Steele; Soren Brage; Kirsten Corder; Nicholas J Wareham; Ulf Ekelund
Physical activity, cardiorespiratory fitness, and the metabolic syndrome in youth.
Journal of applied physiology (Bethesda, Md. : 1985) 2008;105(1):342-51.
2008: Rebecca K Simmons; Stephen Sharp; S Matthijs Boekholdt; Lincoln A Sargeant; Kay-Tee Khaw; Nicholas J Wareham; Simon J Griffin
Evaluation of the Framingham risk score in the European Prospective Investigation of Cancer-Norfolk cohort: does adding glycated hemoglobin improve the prediction of coronary heart disease events?
Archives of internal medicine 2008;168(11):1209-16.
2008: Mushtaqur Rahman; Rebecca K Simmons; Anne-Helen Harding; Nicholas J Wareham; Simon J Griffin
A simple risk score identifies individuals at high risk of developing Type 2 diabetes: a prospective cohort study.
Family practice 2008;25(3):191-6.
2008: Phyo K Myint; Robert N Luben; Nicholas J Wareham; Ailsa A Welch; Sheila A Bingham; Kay-Tee Khaw
Physical activity and fibrinogen concentrations in 23,201 men and women in the EPIC-Norfolk population-based study.
Atherosclerosis 2008;198(2):419-25.
2008: R Lakshman; Nita G Forouhi; R Luben; Sheila Bingham; K Khaw; Nicholas J Wareham; K K Ong
Association between age at menarche and risk of diabetes in adults: results from the EPIC-Norfolk cohort study.
Diabetologia 2008;51(5):781-6.
2008: R K Simmons; S J Griffin; R Steele; Nicholas J Wareham; Ulf Ekelund
Increasing overall physical activity and aerobic fitness is associated with improvements in metabolic risk: cohort analysis of the ProActive trial.
Diabetologia 2008;51(5):787-94.
2008: Zhaogong Zhang; Shuanglin Zhang; Man-Yu Wong; Nicholas J Wareham; Qiuying Sha
An ensemble learning approach jointly modeling main and interaction effects in genetic association studies.
Genetic epidemiology 2008;32(4):285-300.
2008: Claudio Verzilli; Tina Shah; Juan P Casas; Juliet Chapman; Manjinder Sandhu; Sally L Debenham; Matthijs S Boekholdt; Kay-Tee Khaw; Nicholas J Wareham; Richard Judson; Emelia Benjamin; Sekar Kathiresan; Martin G Larson; Jian Rong; Reecha Sofat; Steve E Humphries; Liam Smeeth; Gianpiero Cavalleri; John C Whittaker; Aroon D Hingorani
Bayesian meta-analysis of genetic association studies with different sets of markers.
American journal of human genetics 2008;82(4):859-72.
2008: Yik Y Teo; Michael Inouye; Kerrin S Small; Andrew E Fry; Simon C Potter; Sarah J Dunstan; Mark Seielstad; Inês Barroso; Nicholas J Wareham; Kirk A Rockett; Dominic P Kwiatkowski; Panos Deloukas
Whole genome-amplified DNA: insights and imputation.
Nature methods 2008;5(4):279-80.
2008: Paul G Surtees; Nicholas W J Wainwright; Robert N Luben; Nicholas J Wareham; Sheila A Bingham; Kay-Tee Khaw
Depression and ischemic heart disease mortality: evidence from the EPIC-Norfolk United Kingdom prospective cohort study.
The American journal of psychiatry 2008;165(4):515-23.
2008: Karani S Vimaleswaran; Paul W Franks; Inês Barroso; Soren Brage; Ulf Ekelund; Nicholas J Wareham; Ruth J F Loos
Habitual energy expenditure modifies the association between NOS3 gene polymorphisms and blood pressure.
American journal of hypertension 2008;21(3):297-302.
2008: Tricia M Peters; Ulf Ekelund; Michael Leitzmann; Douglas Easton; Ruth Warren; Robert Luben; Sheila Bingham; Kay-Tee Khaw; Nicholas J Wareham
Physical activity and mammographic breast density in the EPIC-Norfolk cohort study.
American journal of epidemiology 2008;167(5):579-85.
2008: Alireza Moayyeri; Robert N Luben; Sheila A Bingham; Ailsa A Welch; Nicholas J Wareham; Kay-Tee Khaw
Measured height loss predicts fractures in middle-aged and older men and women: the EPIC-Norfolk prospective population study.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2008;23(3):425-32.
2008: Wim A van der Steeg; Ingar Holme; S Matthijs Boekholdt; Mogens Lytken Larsen; Christina Lindahl; Erik S G Stroes; Matti J Tikkanen; Nicholas J Wareham; Ole Faergeman; Anders G Olsson; Terje R Pedersen; Kay-Tee Khaw; John J P Kastelein
High-density lipoprotein cholesterol, high-density lipoprotein particle size, and apolipoprotein A-I: significance for cardiovascular risk: the IDEAL and EPIC-Norfolk studies.
Journal of the American College of Cardiology 2008;51(6):634-42.
2008: Manjinder S Sandhu; Dawn M Waterworth; Sally L Debenham; Eleanor Wheeler; Konstantinos Papadakis; Jing Hua Zhao; Kijoung Song; Xin Yuan; Toby Johnson; Sofie Ashford; Michael Inouye; Robert Luben; Matthew Sims; David Hadley; Wendy L McArdle; Philip Barter; Y Antero Kesäniemi; Robert W Mahley; Ruth McPherson; Scott M Grundy; Sheila A Bingham; Kay-Tee Khaw; Ruth J F Loos; Gérard Waeber; Inês Barroso; David P Strachan; Panos Deloukas; Peter Vollenweider; Nicholas J Wareham; Vincent Mooser
LDL-cholesterol concentrations: a genome-wide association study.
Lancet 2008;371(9611):483-91.
2008: David B Savage; Lanmin Zhai; Balasubramanian Ravikumar; Cheol Soo Choi; Johanna E Snaar; Amanda C McGuire; Sung-Eun Wou; Gema Medina-Gomez; Sheene Kim; Cheryl B Bock; Dyann M Segvich; Bhavana Solanky; Dinesh Deelchand; Antonio Vidal-Puig; Nicholas J Wareham; Gerald I Shulman; Fredrik Karpe; Roy Taylor; Bartholomew A Pederson; Peter J Roach; Stephen O'Rahilly; Anna A DePaoli-Roach
A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice.
PLoS medicine 2008;5(1):e27.
2008: Lisa R Purslow; Manjinder S Sandhu; Nita G Forouhi; Elizabeth H Young; Robert N Luben; Ailsa A Welch; Kay-Tee Khaw; Sheila A Bingham; Nicholas J Wareham
Energy intake at breakfast and weight change: prospective study of 6,764 middle-aged men and women.
American journal of epidemiology 2008;167(2):188-92.
2008: Kay-Tee Khaw; Nicholas J Wareham; Sheila Bingham; Ailsa Welch; Robert Luben; Nicholas E Day
Combined impact of health behaviours and mortality in men and women: the EPIC-Norfolk prospective population study.
PLoS medicine 2008;5(1):e12.
2008: Ann Louise Kinmonth; Nicholas J Wareham; Wendy Hardeman; Stephen Sutton; A Toby Prevost; Thomas Fanshawe; Kate M Williams; Ulf Ekelund; David J Spiegelhalter; Simon J Griffin
Efficacy of a theory-based behavioural intervention to increase physical activity in an at-risk group in primary care (ProActive UK): a randomised trial.
Lancet 2008;371(9606):41-8.
2008: Lisa R Purslow; Elizabeth H Young; Nicholas J Wareham; Nita G Forouhi; Eric J Brunner; Robert N Luben; Ailsa A Welch; Kay-Tee Khaw; Shelia A Bingham; Manjinder S Sandhu
Socioeconomic position and risk of short-term weight gain: prospective study of 14,619 middle-aged men and women.
BMC public health 2008;8():112.
2008: Phyo K Myint; Robert N Luben; Ailsa A Welch; Sheila A Bingham; Nicholas J Wareham; Kay-Tee Khaw
Plasma vitamin C concentrations predict risk of incident stroke over 10 y in 20 649 participants of the European Prospective Investigation into Cancer Norfolk prospective population study.
The American journal of clinical nutrition 2008;87(1):64-9.
2007: Dexter Canoy; S Matthijs Boekholdt; Nicholas J Wareham; Robert Luben; Ailsa Welch; Sheila Bingham; Iain Buchan; Nicholas E Day; Kay-Tee Khaw
Body fat distribution and risk of coronary heart disease in men and women in the European Prospective Investigation Into Cancer and Nutrition in Norfolk cohort: a population-based prospective study.
Circulation 2007;116(25):2933-43.
2007: Kay-Tee Khaw; Mitch Dowsett; Elizabeth Folkerd; Sheila Bingham; Nicholas J Wareham; Robert Luben; Ailsa Welch; Nicholas E Day
Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men: European prospective investigation into cancer in Norfolk (EPIC-Norfolk) Prospective Population Study.
Circulation 2007;116(23):2694-701.
2007: Kirsten Corder; Søren Brage; Calum Mattocks; Andy Ness; Chris Riddoch; Nicholas J Wareham; Ulf Ekelund
Comparison of two methods to assess PAEE during six activities in children.
Medicine and science in sports and exercise 2007;39(12):2180-8.
2007: Jamal S Rana; S Matthijs Boekholdt; P M Ridker; J Wouter Jukema; R Luben; S A Bingham; Nicholas E Day; Nicholas J Wareham; J J P Kastelein; Kay-Tee Khaw
Differential leucocyte count and the risk of future coronary artery disease in healthy men and women: the EPIC-Norfolk Prospective Population Study.
Journal of internal medicine 2007;262(6):678-89.
2007: Kirsten Corder; Søren Brage; Ambady Ramachandran; Chamukuttan Snehalatha; Nicholas J Wareham; Ulf Ekelund
Comparison of two Actigraph models for assessing free-living physical activity in Indian adolescents.
Journal of sports sciences 2007;25(14):1607-11.
2007: Emmanuel Stamatakis; Ulf Ekelund; Nicholas J Wareham
Temporal trends in physical activity in England: the Health Survey for England 1991 to 2004.
Preventive medicine 2007;45(6):416-23.
2007: Benoit J Arsenault; Isabelle Lemieux; Jean-Pierre Després; Nicholas J Wareham; Robert Luben; John J P Kastelein; Kay-Tee Khaw; S Matthijs Boekholdt
Cholesterol levels in small LDL particles predict the risk of coronary heart disease in the EPIC-Norfolk prospective population study.
European heart journal 2007;28(22):2770-7.
2007: Rakesh S Birjmohun; Geesje M Dallinga-Thie; Jan Albert Kuivenhoven; Erik S G Stroes; James D Otvos; Nicholas J Wareham; Robert Luben; John J P Kastelein; Kay-Tee Khaw; S Matthijs Boekholdt
Apolipoprotein A-II is inversely associated with risk of future coronary artery disease.
Circulation 2007;116(18):2029-35.
2007: RK Simmons; Simon J Griffin; Nicholas J Wareham
Researching how to realize the potential of diabetes prevention.
Diabetic medicine : a journal of the British Diabetic Association 2007;24(10):1055-7.
2007: E H Young; Nicholas J Wareham; S Farooqi; Anke Hinney; Johannes Hebebrand; André Scherag; S O'rahilly; Inês Barroso; Manjinder S Sandhu
The V103I polymorphism of the MC4R gene and obesity: population based studies and meta-analysis of 29 563 individuals.
International journal of obesity (2005) 2007;31(9):1437-41.
2007: Nicholas J Wareham
Epidemiological studies of physical activity and diabetes risk, and implications for diabetes prevention.
Applied physiology, nutrition, and metabolism = Physiologie appliquée, nutrition et métabolisme 2007;32(4):778-82.
2007: Manjinder S Sandhu; Michael Weedon; Katherine A Fawcett; Jon Wasson; Sally L Debenham; Allan Daly; Hana Lango; Timothy M Frayling; Rosalind J Neumann; Richard Sherva; Ilana Blech; Paul D P Pharoah; Colin N A Palmer; Charlotte Kimber; Roger Tavendale; Andrew D Morris; Mark I McCarthy; Mark Walker; Graham A Hitman; Benjamin Glaser; M Alan Permutt; Andrew T Hattersley; Nicholas J Wareham; Inês Barroso
Common variants in WFS1 confer risk of type 2 diabetes.
Nature genetics 2007;39(8):951-3.
2007: Ulf Ekelund; Paul W Franks; Stephen Sharp; Søren Brage; Nicholas J Wareham
Increase in physical activity energy expenditure is associated with reduced metabolic risk independent of change in fatness and fitness.
Diabetes care 2007;30(8):2101-6.
2007: RK Simmons; Anne-Helen Harding; Nicholas J Wareham; Simon J Griffin
Do simple questions about diet and physical activity help to identify those at risk of Type 2 diabetes?
Diabetic medicine : a journal of the British Diabetic Association 2007;24(8):830-5.
2007: Søren Brage; Ulf Ekelund; Niels Brage; Mark A Hennings; Karsten Froberg; Paul W Franks; Nicholas J Wareham
Hierarchy of individual calibration levels for heart rate and accelerometry to measure physical activity.
Journal of applied physiology (Bethesda, Md. : 1985) 2007;103(2):682-92.
2007: Marijn C Meuwese; Erik S G Stroes; Stanley L Hazen; Joram N I van Miert; Jan Albert Kuivenhoven; Robert G Schaub; Nicholas J Wareham; Robert Luben; John J P Kastelein; Kay-Tee Khaw; S Matthijs Boekholdt
Serum myeloperoxidase levels are associated with the future risk of coronary artery disease in apparently healthy individuals: the EPIC-Norfolk Prospective Population Study.
Journal of the American College of Cardiology 2007;50(2):159-65.
2007: Barbara Heude; Ken K Ong; Robert Luben; Nicholas J Wareham; Manjinder S Sandhu
Study of association between common variation in the insulin-like growth factor 2 gene and indices of obesity and body size in middle-aged men and women.
The Journal of clinical endocrinology and metabolism 2007;92(7):2734-8.
2007: Ruth J F Loos; Paul W Franks; Richard W Francis; Inês Barroso; Fiona M Gribble; David B Savage; Ken K Ong; Stephen O'Rahilly; Nicholas J Wareham
TCF7L2 polymorphisms modulate proinsulin levels and beta-cell function in a British Europid population.
Diabetes 2007;56(7):1943-7.
2007: Phyo K Myint; Robert N Luben; Paul G Surtees; Nicholas W J Wainwright; Ailsa A Welch; Sheila A Bingham; Nicholas J Wareham; Richard D Smith; Ian M Harvey; Kay-Tee Khaw
Self-reported mental health-related quality of life and mortality in men and women in the European Prospective Investigation into Cancer (EPIC-Norfolk): a prospective population study.
Psychosomatic medicine 2007;69(5):410-4.
2007: Aline Meirhaeghe; Manjinder S Sandhu; Mark I McCarthy; Pascal de Groote; Dominique Cottel; Dominique Arveiler; Jean Ferrières; Christopher J Groves; Andrew T Hattersley; Graham A Hitman; Mark Walker; Nicholas J Wareham; Philippe Amouyel
Association between the T-381C polymorphism of the brain natriuretic peptide gene and risk of type 2 diabetes in human populations.
Human molecular genetics 2007;16(11):1343-50.
2007: Robert K Semple; Nils H Halberg; Keith Burling; Maria A Soos; Todd D Schraw; Jian'an Luan; Elaine Cochran; David D Dunger; Nicholas J Wareham; Philipp E Scherer; Phillip Gorden; Stephen O'Rahilly
Paradoxical elevation of high-molecular weight adiponectin in acquired extreme insulin resistance due to insulin receptor antibodies.
Diabetes 2007;56(6):1712-7.
2007: Yen-Ling Low; Alison M Dunning; Mitch Dowsett; Elizabeth Folkerd; Deborah Doody; James Taylor; Amit Bhaniani; Robert Luben; Kay-Tee Khaw; Nicholas J Wareham; Sheila A Bingham
Phytoestrogen exposure is associated with circulating sex hormone levels in postmenopausal women and interact with ESR1 and NR1I2 gene variants.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(5):1009-16.
2007: Mei-Fen Chan; Mitch Dowsett; Elizabeth Folkerd; Sheila Bingham; Nicholas J Wareham; Robert Luben; Ailsa Welch; Kay-Tee Khaw
Usual physical activity and endogenous sex hormones in postmenopausal women: the European prospective investigation into cancer-norfolk population study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(5):900-5.
2007: Wim A van der Steeg; S Matthijs Boekholdt; Evan A Stein; Karim El Harchaoui; Erik S G Stroes; Manjinder S Sandhu; Nicholas J Wareham; J Wouter Jukema; Robert Luben; Aeilko H Zwinderman; John J P Kastelein; Kay-Tee Khaw
Role of the apolipoprotein B-apolipoprotein A-I ratio in cardiovascular risk assessment: a case-control analysis in EPIC-Norfolk.
Annals of internal medicine 2007;146(9):640-8.
2007: Paul G Surtees; Nicholas W J Wainwright; Robert L Luben; Nicholas J Wareham; Sheila A Bingham; Kay-Tee Khaw
Adaptation to social adversity is associated with stroke incidence: evidence from the EPIC-Norfolk prospective cohort study.
Stroke; a journal of cerebral circulation 2007;38(5):1447-53.
2007: Nita G Forouhi; Anne-Helen Harding; M Allison; Manjinder S Sandhu; Ailsa Welch; R Luben; Sheila Bingham; Kay-Tee Khaw; Nicholas J Wareham
Elevated serum ferritin levels predict new-onset type 2 diabetes: results from the EPIC-Norfolk prospective study.
Diabetologia 2007;50(5):949-56.
2007: Ziad Mallat; Joelle Benessiano; Tabassome Simon; Stéphane Ederhy; Carla Sebella-Arguelles; Ariel Cohen; Virginie Huart; Nicholas J Wareham; Robert Luben; Kay-Tee Khaw; Alain Tedgui; S Matthijs Boekholdt
Circulating secretory phospholipase A2 activity and risk of incident coronary events in healthy men and women: the EPIC-Norfolk study.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(5):1177-83.
2007: Paul W Franks; Ruth J F Loos; Søren Brage; Stephen O'Rahilly; Nicholas J Wareham; Ulf Ekelund
Physical activity energy expenditure may mediate the relationship between plasma leptin levels and worsening insulin resistance independently of adiposity.
Journal of applied physiology (Bethesda, Md. : 1985) 2007;102(5):1921-6.
2007: José L Mesa; Ruth J F Loos; Paul W Franks; Ken K Ong; Jian'an Luan; Stephen O'Rahilly; Nicholas J Wareham; Inês Barroso
Lamin A/C polymorphisms, type 2 diabetes, and the metabolic syndrome: case-control and quantitative trait studies.
Diabetes 2007;56(3):884-9.
2007: Karen Tan; Wendy Kimber; Jian'an Luan; Maria A Soos; Robert K Semple; Nicholas J Wareham; Stephen O'Rahilly; Inês Barroso
Analysis of genetic variation in Akt2/PKB-beta in severe insulin resistance, lipodystrophy, type 2 diabetes, and related metabolic phenotypes.
Diabetes 2007;56(3):714-9.
2007: Nicholas W J Wainwright; Paul G Surtees; Nicholas J Wareham; B D W Harrison
Psychosocial factors and asthma in a community sample of older adults.
Journal of psychosomatic research 2007;62(3):357-61.
2007: S C Collins; Jian'an Luan; A J Thompson; Allan Daly; Robert K Semple; Stephen O'Rahilly; Nicholas J Wareham; Inês Barroso
Adiponectin receptor genes: mutation screening in syndromes of insulin resistance and association studies for type 2 diabetes and metabolic traits in UK populations.
Diabetologia 2007;50(3):555-62.
2007: Paul W Franks; Ulf Ekelund; Søren Brage; Jian'an Luan; Alan J Schafer; Stephen O'Rahilly; Inês Barroso; Nicholas J Wareham
PPARGC1A coding variation may initiate impaired NEFA clearance during glucose challenge.
Diabetologia 2007;50(3):569-73.
2007: C-C C Hung; Jian'an Luan; M Sims; Julia M Keogh; C Hall; Nicholas J Wareham; Stephen O'Rahilly; I Sadaf Farooqi
Studies of the SIM1 gene in relation to human obesity and obesity-related traits.
International journal of obesity (2005) 2007;31(3):429-34.
2007: Karim El Harchaoui; Wim A van der Steeg; Erik S G Stroes; Jan Albert Kuivenhoven; James D Otvos; Nicholas J Wareham; Barbara A Hutten; John J P Kastelein; Kay-Tee Khaw; S Matthijs Boekholdt
Value of low-density lipoprotein particle number and size as predictors of coronary artery disease in apparently healthy men and women: the EPIC-Norfolk Prospective Population Study.
Journal of the American College of Cardiology 2007;49(5):547-53.
2007: Ulf Ekelund; Simon J Griffin; Nicholas J Wareham
Physical activity and metabolic risk in individuals with a family history of type 2 diabetes.
Diabetes care 2007;30(2):337-42.
2007: Nita G Forouhi; J Luan; S Hennings; Nicholas J Wareham
Incidence of Type 2 diabetes in England and its association with baseline impaired fasting glucose: the Ely study 1990-2000.
Diabetic medicine : a journal of the British Diabetic Association 2007;24(2):200-7.
2007: Phyo K Myint; Shubhada Sinha; Nicholas J Wareham; Sheila A Bingham; Robert N Luben; Ailsa A Welch; Kay-Tee Khaw
Glycated hemoglobin and risk of stroke in people without known diabetes in the European Prospective Investigation into Cancer (EPIC)-Norfolk prospective population study: a threshold relationship?
Stroke; a journal of cerebral circulation 2007;38(2):271-5.
2007: Stephen Kaptoge; Rupert W Jakes; Nichola Dalzell; Nicholas J Wareham; Kay-Tee Khaw; Nigel Loveridge; Thomas J Beck; Jonathan Reeve
Effects of physical activity on evolution of proximal femur structure in a younger elderly population.
Bone 2007;40(2):506-15.
2007: Phyo K Myint; Paul G Surtees; Nicholas W J Wainwright; Nicholas J Wareham; Sheila A Bingham; Robert N Luben; Ailsa A Welch; Richard D Smith; Ian M Harvey; Kay-Tee Khaw
Modifiable lifestyle behaviors and functional health in the European Prospective Investigation into Cancer (EPIC)-Norfolk population study.
Preventive medicine 2007;44(2):109-16.
2007: Paul W Franks; Jose-Luis Mesa; Anne-Helen Harding; Nicholas J Wareham
Gene-lifestyle interaction on risk of type 2 diabetes.
Nutrition, metabolism, and cardiovascular diseases : NMCD 2007;17(2):104-24.
2007: Ruth J F Loos; Inês Barroso; Stephen O'Rahilly; Nicholas J Wareham
Comment on "A common genetic variant is associated with adult and childhood obesity".
Science (New York, N.Y.) 2007;315(5809):187; author reply 187.
2007: Phyo K Myint; Ailsa A Welch; Sheila A Bingham; Paul G Surtees; Nicholas W J Wainwright; Robert N Luben; Nicholas J Wareham; Richard D Smith; Ian M Harvey; Nicholas E Day; Kay-Tee Khaw
Fruit and vegetable consumption and self-reported functional health in men and women in the European Prospective Investigation into Cancer-Norfolk (EPIC-Norfolk): a population-based cross-sectional study.
Public health nutrition 2007;10(1):34-41.
2007: Sabine Pinedo; Maud N Vissers; Klaus Von Bergmann; Karim Elharchaoui; Dieter Lütjohann; Robert Luben; Nicholas J Wareham; John J P Kastelein; Kay-Tee Khaw; S Matthijs Boekholdt
Plasma levels of plant sterols and the risk of coronary artery disease: the prospective EPIC-Norfolk Population Study.
Journal of lipid research 2007;48(1):139-44.
2007: Ulf Ekelund; Ken K Ong; Yvonne Linné; Martin Neovius; Søren Brage; David D Dunger; Nicholas J Wareham; Stephan Rössner
Association of weight gain in infancy and early childhood with metabolic risk in young adults.
The Journal of clinical endocrinology and metabolism 2007;92(1):98-103.
2007: Ulf Ekelund; Stefan Särnblad; Søren Brage; J Ryberg; Nicholas J Wareham; Jan Aman
Does physical activity equally predict gain in fat mass among obese and nonobese young adults?
International journal of obesity (2005) 2007;31(1):65-71.
2006: Ailsa A Welch; Sheila A Bingham; Jessica Ive; Marlin Friesen; Nicholas J Wareham; Elio Riboli; Kay-Tee Khaw
Dietary fish intake and plasma phospholipid n-3 polyunsaturated fatty acid concentrations in men and women in the European Prospective Investigation into Cancer-Norfolk United Kingdom cohort.
The American journal of clinical nutrition 2006;84(6):1330-9.
2006: S Matthijs Boekholdt; Manjinder S Sandhu; Nicholas E Day; Robert Luben; Sheila A Bingham; Ron J G Peters; Nicholas J Wareham; Kay-Tee Khaw
Physical activity, C-reactive protein levels and the risk of future coronary artery disease in apparently healthy men and women: the EPIC-Norfolk prospective population study.
European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 2006;13(6):970-6.
2006: Kay-Tee Khaw; Nicholas J Wareham
Glycated hemoglobin as a marker of cardiovascular risk.
Current opinion in lipidology 2006;17(6):637-43.
2006: Dexter Canoy; Nicholas J Wareham; Robert Luben; Ailsa Welch; Sheila Bingham; Nicholas E Day; Kay-Tee Khaw
Serum lipid concentration in relation to anthropometric indices of central and peripheral fat distribution in 20,021 British men and women: results from the EPIC-Norfolk population-based cohort study.
Atherosclerosis 2006;189(2):420-7.
2006: K A Fawcett; Nicholas J Wareham; Jian'an Luan; H Syddall; C Cooper; Stephen O'Rahilly; I N M Day; Manjinder S Sandhu; Inês Barroso
PARL Leu262Val is not associated with fasting insulin levels in UK populations.
Diabetologia 2006;49(11):2649-52.
2006: Anne-Helen Harding; R J F Loos; Jian'an Luan; Stephen O'Rahilly; Nicholas J Wareham; Inês Barroso
Polymorphisms in the gene encoding sterol regulatory element-binding factor-1c are associated with type 2 diabetes.
Diabetologia 2006;49(11):2642-8.
2006: Tymen T Keller; D Choi; C Nagel; H Te Velthuis; V E A Gerdes; Nicholas J Wareham; Sheila A Bingham; Robert Luben; C Erik Hack; Pieter H Reitsma; Marcel Levi; Kay-Tee Khaw; S Matthijs Boekholdt
Tissue factor serum levels and the risk of future coronary artery disease in apparently healthy men and women: the EPIC-Norfolk prospective population study.
Journal of thrombosis and haemostasis : JTH 2006;4(11):2391-6.
2006: Maura Agostini; Erik Schoenmakers; Catherine Mitchell; Istvan Szatmari; David Savage; Aaron Smith; Odelia Rajanayagam; Robert K Semple; Jian'an Luan; Louise Bath; Anthony Zalin; Mourad Labib; Sudhesh Kumar; Helen Simpson; Dirk Blom; David Marais; John W R Schwabe; Inês Barroso; Richard C Trembath; Nicholas J Wareham; Laszlo Nagy; Mark Gurnell; Stephen O'Rahilly; Krishna Chatterjee
Non-DNA binding, dominant-negative, human PPARgamma mutations cause lipodystrophic insulin resistance.
Cell metabolism 2006;4(4):303-11.
2006: Phyo K Myint; Ailsa A Welch; Sheila A Bingham; Robert N Luben; Nicholas J Wareham; Nicholas E Day; Kay-Tee Khaw
Habitual fish consumption and risk of incident stroke: the European Prospective Investigation into Cancer (EPIC)-Norfolk prospective population study.
Public health nutrition 2006;9(7):882-8.
2006: Tymen T Keller; Sander I van Leuven; Marijn C Meuwese; Nicholas J Wareham; Robert Luben; Erik S G Stroes; C Erik Hack; Marcel Levi; Kay-Tee Khaw; S Matthijs Boekholdt
Serum levels of mannose-binding lectin and the risk of future coronary artery disease in apparently healthy men and women.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(10):2345-50.
2006: Yen-Ling Low; Alison M Dunning; Mitch Dowsett; Robert N Luben; Kay-Tee Khaw; Nicholas J Wareham; Sheila A Bingham
Implications of gene-environment interaction in studies of gene variants in breast cancer: an example of dietary isoflavones and the D356N polymorphism in the sex hormone-binding globulin gene.
Cancer research 2006;66(18):8980-3.
2006: S Matthijs Boekholdt; Marijn C Meuwese; Nicholas E Day; Robert Luben; Ailsa Welch; Nicholas J Wareham; Kay-Tee Khaw
Plasma concentrations of ascorbic acid and C-reactive protein, and risk of future coronary artery disease, in apparently healthy men and women: the EPIC-Norfolk prospective population study.
The British journal of nutrition 2006;96(3):516-22.
2006: Stefan F C Vaessen; Frank G Schaap; Jan Albert Kuivenhoven; Albert K Groen; Barbara A Hutten; S Matthijs Boekholdt; Hiroaki Hattori; Manjinder S Sandhu; Sheila A Bingham; Robert Luben; Jutta A Palmen; Nicholas J Wareham; Steve E Humphries; John J P Kastelein; Philippa J Talmud; Kay-Tee Khaw
Apolipoprotein A-V, triglycerides and risk of coronary artery disease: the prospective Epic-Norfolk Population Study.
Journal of lipid research 2006;47(9):2064-70.
2006: Kay-Tee Khaw; Rupert W Jakes; Sheila Bingham; Ailsa Welch; Robert Luben; Nicholas E Day; Nicholas J Wareham
Work and leisure time physical activity assessed using a simple, pragmatic, validated questionnaire and incident cardiovascular disease and all-cause mortality in men and women: The European Prospective Investigation into Cancer in Norfolk prospective population study.
International journal of epidemiology 2006;35(4):1034-43.
2006: Robert K Semple; Maria A Soos; Jian'an Luan; C S Mitchell; J C Wilson; Mark Gurnell; Elaine Cochran; Phillip Gorden; V Krishna K Chatterjee; Nicholas J Wareham; Stephen O'Rahilly
Elevated plasma adiponectin in humans with genetically defective insulin receptors.
The Journal of clinical endocrinology and metabolism 2006;91(8):3219-23.
2006: S Matthijs Boekholdt; C Erik Hack; Manjinder S Sandhu; Robert Luben; Sheila A Bingham; Nicholas J Wareham; Ron J G Peters; J Wouter Jukema; Nicholas E Day; John J P Kastelein; Kay-Tee Khaw
C-reactive protein levels and coronary artery disease incidence and mortality in apparently healthy men and women: the EPIC-Norfolk prospective population study 1993-2003.
Atherosclerosis 2006;187(2):415-22.
2006: Stephen O'Rahilly; Nicholas J Wareham
Genetic variants and common diseases--better late than never.
The New England journal of medicine 2006;355(3):306-8.
2006: C Glümer; M Yuyun; S Griffin; D Farewell; David J Spiegelhalter; Ann Louise Kinmonth; Nicholas J Wareham
What determines the cost-effectiveness of diabetes screening?
Diabetologia 2006;49(7):1536-44.
2006: Phyo K Myint; Robert N Luben; Paul G Surtees; Nicholas W J Wainwright; Ailsa A Welch; Sheila A Bingham; Nicholas E Day; Nicholas J Wareham; Kay-Tee Khaw
Relation between self-reported physical functional health and chronic disease mortality in men and women in the European Prospective Investigation into Cancer (EPIC-Norfolk): a prospective population study.
Annals of epidemiology 2006;16(6):492-500.
2006: Phyo K Myint; Ailsa A Welch; Robert N Luben; Nicholas W J Wainwright; Paul G Surtees; Sheila A Bingham; Nicholas J Wareham; Richard D Smith; Ian M Harvey; Kay-Tee Khaw
Obesity indices and self-reported functional health in men and women in the EPIC-Norfolk.
Obesity (Silver Spring, Md.) 2006;14(5):884-93.
2006: Nita G Forouhi; B Balkau; K Borch-Johnsen; J Dekker; C Glumer; Q Qiao; A Spijkerman; R Stolk; A Tabac; Nicholas J Wareham
The threshold for diagnosing impaired fasting glucose: a position statement by the European Diabetes Epidemiology Group.
Diabetologia 2006;49(5):822-7.
2006: RK Simmons; Anne-Helen Harding; Rupert W Jakes; Ailsa Welch; Nicholas J Wareham; Simon J Griffin
How much might achievement of diabetes prevention behaviour goals reduce the incidence of diabetes if implemented at the population level?
Diabetologia 2006;49(5):905-11.
2006: Anne-Helen Harding; Simon J Griffin; Nicholas J Wareham
Population impact of strategies for identifying groups at high risk of type 2 diabetes.
Preventive medicine 2006;42(5):364-8.
2006: Ulf Ekelund; Hanna Sepp; Sören Brage; Wulf Becker; Rupert W Jakes; Mark Hennings; Nicholas J Wareham
Criterion-related validity of the last 7-day, short form of the International Physical Activity Questionnaire in Swedish adults.
Public health nutrition 2006;9(2):258-65.
2006: Sumit Bhattacharyya; Jian'an Luan; Benjamin G Challis; Julia Keogh; Montague Carl; John Brennand; John Morten; Sarah Lowenbeim; Suzanne Jenkins; I Sadaf Farooqi; Nicholas J Wareham; Stephen O'Rahilly
Sequence variants in the melatonin-related receptor gene (GPR50) associate with circulating triglyceride and HDL levels.
Journal of lipid research 2006;47(4):761-6.
2006: Inês Barroso; Jian'an Luan; Manjinder S Sandhu; Paul W Franks; Vivion E F Crowley; Alan J Schafer; Stephen O'Rahilly; Nicholas J Wareham
Meta-analysis of the Gly482Ser variant in PPARGC1A in type 2 diabetes and related phenotypes.
Diabetologia 2006;49(3):501-5.
2006: Jaap Rip; Melchior C Nierman; Nicholas J Wareham; Robert Luben; Sheila A Bingham; Nicholas E Day; Joram N I van Miert; Barbara A Hutten; John J P Kastelein; Jan Albert Kuivenhoven; Kay-Tee Khaw; S Matthijs Boekholdt
Serum lipoprotein lipase concentration and risk for future coronary artery disease: the EPIC-Norfolk prospective population study.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(3):637-42.
2006: Søren Brage; Niels Brage; Ulf Ekelund; Jian'an Luan; Paul W Franks; Karsten Froberg; Nicholas J Wareham
Effect of combined movement and heart rate monitor placement on physical activity estimates during treadmill locomotion and free-living.
European journal of applied physiology 2006;96(5):517-24.
2006: Ulf Ekelund; Ken Ong; Yvonne Linné; Martin Neovius; Søren Brage; David D Dunger; Nicholas J Wareham; Stephan Rössner
Upward weight percentile crossing in infancy and early childhood independently predicts fat mass in young adults: the Stockholm Weight Development Study (SWEDES).
The American journal of clinical nutrition 2006;83(2):324-30.
2006: Yung Seng Lee; Benjamin G Challis; Darren A Thompson; Giles S H Yeo; Julia M Keogh; Michael E Madonna; Vicki Wraight; Matthew Sims; Vincent Vatin; David Meyre; Julian Shield; Christine Burren; Zala Ibrahim; Tim Cheetham; Peter Swift; Anthea Blackwood; Chiao-Chien Connie Hung; Nicholas J Wareham; philippe froguel; Glenn L Millhauser; Stephen O'Rahilly; I Sadaf Farooqi
A POMC variant implicates beta-melanocyte-stimulating hormone in the control of human energy balance.
Cell metabolism 2006;3(2):135-40.
2006: Phyo K Myint; Ailsa A Welch; Sheila A Bingham; Robert N Luben; Nicholas J Wareham; Nicholas E Day; Kay-Tee Khaw
Smoking predicts long-term mortality in stroke: The European Prospective Investigation into Cancer (EPIC)-Norfolk prospective population study.
Preventive medicine 2006;42(2):128-31.
2006: Rebecca K Simmons; Nicholas J Wareham
Commentary: obesity is not a newly recognized public health problem--a commentary of Breslow's 1952 paper on 'public health aspects of weight control'.
International journal of epidemiology 2006;35(1):14-6.
2006: Yen-Ling Low; James I Taylor; Philip B Grace; Angela A Mulligan; Ailsa A Welch; Serena Scollen; Alison M Dunning; Robert N Luben; Kay-Tee Khaw; Nicholas E Day; Nicholas J Wareham; Sheila A Bingham
Phytoestrogen exposure, polymorphisms in COMT, CYP19, ESR1, and SHBG genes, and their associations with prostate cancer risk.
Nutrition and cancer 2006;56(1):31-9.
2006: Phyo K Myint; Robert N Luben; Nicholas J Wareham; Ailsa A Welch; Sheila A Bingham; Nicholas E Day; Kay-Tee Khaw
Combined work and leisure physical activity and risk of stroke in men and women in the European prospective investigation into Cancer-Norfolk Prospective Population Study.
Neuroepidemiology 2006;27(3):122-9.
2006: Phyo K Myint; Robert N Luben; Ailsa A Welch; Sheila A Bingham; Nicholas J Wareham; Kay-Tee Khaw
Effect of age on the relationship of occupational social class with prevalence of modifiable cardiovascular risk factors and cardiovascular diseases. A population-based cross-sectional study from European Prospective Investigation into Cancer - Norfolk (EPIC-Norfolk).
Gerontology 2006;52(1):51-8.
2006: Ali S Alzahrani; Manjinder S Sandhu; Robert N Luben; Deborah Thompson; Caroline Baynes; Karen A Pooley; Craig Luccarini; Hannah Munday; Barbara Perkins; Paula Smith; Paul D P Pharoah; Nicholas J Wareham; Douglas F Easton; Bruce A J Ponder; Alison M Dunning
IGF1 and IGFBP3 tagging polymorphisms are associated with circulating levels of IGF1, IGFBP3 and risk of breast cancer.
Human molecular genetics 2006;15(1):1-10.
2005: Dexter Canoy; Nicholas J Wareham; Ailsa Welch; Sheila Bingham; Robert Luben; Nicholas E Day; Kay-Tee Khaw
Plasma ascorbic acid concentrations and fat distribution in 19,068 British men and women in the European Prospective Investigation into Cancer and Nutrition Norfolk cohort study.
The American journal of clinical nutrition 2005;82(6):1203-9.
2005: Wendy Hardeman; Stephen Sutton; Simon Griffin; Marie Johnston; Anthony White; Nicholas J Wareham; Ann Louise Kinmonth
A causal modelling approach to the development of theory-based behaviour change programmes for trial evaluation.
Health education research 2005;20(6):676-87.
2005: Yen-Ling Low; James I Taylor; Philip B Grace; Mitch Dowsett; Elizabeth Folkerd; Deborah Doody; Alison M Dunning; Serena Scollen; Angela A Mulligan; Ailsa A Welch; Robert N Luben; Kay-Tee Khaw; Nicholas E Day; Nicholas J Wareham; Sheila A Bingham
Polymorphisms in the CYP19 gene may affect the positive correlations between serum and urine phytoestrogen metabolites and plasma androgen concentrations in men.
The Journal of nutrition 2005;135(11):2680-6.
2005: Kirsten Corder; Søren Brage; Nicholas J Wareham; Ulf Ekelund
Comparison of PAEE from combined and separate heart rate and movement models in children.
Medicine and science in sports and exercise 2005;37(10):1761-7.
2005: Radim Jurca; Andrew S Jackson; Michael J LaMonte; James R Morrow; Steven N Blair; Nicholas J Wareham; William L Haskell; Willem van Mechelen; Timothy S Church; John M Jakicic; Raija Laukkanen
Assessing cardiorespiratory fitness without performing exercise testing.
American journal of preventive medicine 2005;29(3):185-93.
2005: Manjinder S Sandhu; Barbara Heude; Elizabeth H Young; Robert Luben; Jian'an Luan; Kay-Tee Khaw; John Todd; Nicholas J Wareham
INS VNTR class genotype and indexes of body size and obesity: population-based studies of 7,999 middle-aged men and women.
Diabetes 2005;54(9):2812-5.
2005: Paul W Franks; Jian'an Luan; Inês Barroso; Søren Brage; Jose Luis Gonzalez Sanchez; Ulf Ekelund; Manuel Serrano Ríos; Alan J Schafer; Stephen O'Rahilly; Nicholas J Wareham
Variation in the eNOS gene modifies the association between total energy expenditure and glucose intolerance.
Diabetes 2005;54(9):2795-801.
2005: Fabienne LESUEUR; Paul D P Pharoah; Stewart Laing; Shahana Ahmed; Clare Jordan; Paula L Smith; Robert Luben; Nicholas J Wareham; Douglas F Easton; Alison M Dunning; Bruce A J Ponder
Allelic association of the human homologue of the mouse modifier Ptprj with breast cancer.
Human molecular genetics 2005;14(16):2349-56.
2005: Paul W Franks; Søren Brage; Jian'an Luan; Ulf Ekelund; Mushtaquar Rahman; I Sadaf Farooqi; Ian Halsall; Stephen O'Rahilly; Nicholas J Wareham
Leptin predicts a worsening of the features of the metabolic syndrome independently of obesity.
Obesity research 2005;13(8):1476-84.
2005: Dexter Canoy; Nicholas J Wareham; Robert Luben; Ailsa Welch; Sheila Bingham; Nicholas E Day; Kay-Tee Khaw
Cigarette smoking and fat distribution in 21,828 British men and women: a population-based study.
Obesity research 2005;13(8):1466-75.
2005: Nicholas J Wareham; Nita G Forouhi
Is there really an epidemic of diabetes?
Diabetologia 2005;48(8):1454-5.
2005: Alejandro Lucia; Félix Gómez-Gallego; Inês Barroso; Manuel Rabadán; Fernando Bandrés; Alejandro F San Juan; José L Chicharro; Ulf Ekelund; Søren Brage; Conrad P Earnest; Nicholas J Wareham; Paul W Franks
PPARGC1A genotype (Gly482Ser) predicts exceptional endurance capacity in European men.
Journal of applied physiology (Bethesda, Md. : 1985) 2005;99(1):344-8.
2005: Nicholas J Wareham; Esther M F van Sluijs; Ulf Ekelund
Physical activity and obesity prevention: a review of the current evidence.
The Proceedings of the Nutrition Society 2005;64(2):229-47.
2005: Ulf Ekelund; Søren Brage; Paul W Franks; Susie Hennings; Sue Emms; Man-Yu Wong; Nicholas J Wareham
Physical activity energy expenditure predicts changes in body composition in middle-aged healthy whites: effect modification by age.
The American journal of clinical nutrition 2005;81(5):964-9.
2005: Ulf Ekelund; Søren Brage; Paul W Franks; Susie Hennings; Sue Emms; Nicholas J Wareham
Physical activity energy expenditure predicts progression toward the metabolic syndrome independently of aerobic fitness in middle-aged healthy Caucasians: the Medical Research Council Ely Study.
Diabetes care 2005;28(5):1195-200.
2005: Matthew F Yuyun; Amanda I Adler; Nicholas J Wareham
What is the evidence that microalbuminuria is a predictor of cardiovascular disease events?
Current opinion in nephrology and hypertension 2005;14(3):271-6.
2005: Shubhada Sinha; Robert N Luben; Ailsa Welch; Sheila Bingham; Nicholas J Wareham; Nicholas E Day; Kay-Tee Khaw
Fibrinogen and cigarette smoking in men and women in the European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) population.
European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 2005;12(2):144-50.
2005: Søren Brage; Niels Brage; Paul W Franks; Ulf Ekelund; Nicholas J Wareham
Reliability and validity of the combined heart rate and movement sensor Actiheart.
European journal of clinical nutrition 2005;59(4):561-70.
2005: S Matthijs Boekholdt; Tymen T Keller; Nicholas J Wareham; Robert Luben; Sheila A Bingham; Nicholas E Day; Manjinder S Sandhu; J Wouter Jukema; John J P Kastelein; C Erik Hack; Kay-Tee Khaw
Serum levels of type II secretory phospholipase A2 and the risk of future coronary artery disease in apparently healthy men and women: the EPIC-Norfolk Prospective Population Study.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(4):839-46.
2005: Ulf Ekelund; Martin Neovius; Yvonne Linné; Søren Brage; Nicholas J Wareham; Stephan Rössner
Associations between physical activity and fat mass in adolescents: the Stockholm Weight Development Study.
The American journal of clinical nutrition 2005;81(2):355-60.
2005: Stephen O'Rahilly; Inês Barroso; Nicholas J Wareham
Genetic factors in type 2 diabetes: the end of the beginning?
Science (New York, N.Y.) 2005;307(5708):370-3.
2005: Yen-Ling Low; James I Taylor; Philip B Grace; Mitch Dowsett; Serena Scollen; Alison M Dunning; Angela A Mulligan; Ailsa A Welch; Robert N Luben; Kay-Tee Khaw; Nicholas E Day; Nicholas J Wareham; Sheila A Bingham
Phytoestrogen exposure correlation with plasma estradiol in postmenopausal women in European Prospective Investigation of Cancer and Nutrition-Norfolk may involve diet-gene interactions.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(1):213-20.
2004: Rupert W Jakes; Nicholas E Day; Robert Luben; Ailsa Welch; Sheila Bingham; Jo Mitchell; Susie Hennings; Kirsten L Rennie; Nicholas J Wareham
Adjusting for energy intake--what measure to use in nutritional epidemiological studies?
International journal of epidemiology 2004;33(6):1382-6.
2004: Nicholas E Day; Man-Yu Wong; Sheila Bingham; Kay-Tee Khaw; Robert Luben; Karin B Michels; Ailsa Welch; Nicholas J Wareham
Correlated measurement error--implications for nutritional epidemiology.
International journal of epidemiology 2004;33(6):1373-81.
2004: Kay-Tee Khaw; Sheila Bingham; Ailsa Welch; Robert Luben; Eoin O'Brien; Nicholas J Wareham; Nicholas E Day
Blood pressure and urinary sodium in men and women: the Norfolk Cohort of the European Prospective Investigation into Cancer (EPIC-Norfolk).
The American journal of clinical nutrition 2004;80(5):1397-403.
2004: Kalpana Kaushal; Adrian H Heald; Kirk W Siddals; Manjinder S Sandhu; David D Dunger; J Martin Gibson; Nicholas J Wareham
The impact of abnormalities in IGF and inflammatory systems on the metabolic syndrome.
Diabetes care 2004;27(11):2682-8.
2004: Dexter Canoy; Robert Luben; Ailsa Welch; Sheila Bingham; Nicholas J Wareham; Nicholas E Day; Kay-Tee Khaw
Fat distribution, body mass index and blood pressure in 22,090 men and women in the Norfolk cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC-Norfolk) study.
Journal of hypertension 2004;22(11):2067-74.
2004: Søren Brage; Niels Wedderkopp; Ulf Ekelund; Paul W Franks; Nicholas J Wareham; Lars Bo Andersen; Karsten Froberg
Objectively measured physical activity correlates with indices of insulin resistance in Danish children. The European Youth Heart Study (EYHS).
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2004;28(11):1503-8.
2004: Kate Williams; A Toby Prevost; Simon Griffin; Wendy Hardeman; William Hollingworth; David J Spiegelhalter; Stephen Sutton; Ulf Ekelund; Nicholas J Wareham; Ann Louise Kinmonth
The ProActive trial protocol - a randomised controlled trial of the efficacy of a family-based, domiciliary intervention programme to increase physical activity among individuals at high risk of diabetes [ISRCTN61323766].
BMC public health 2004;4():48.
2004: Sumit Bhattacharyya; Jian'an Luan; I Sadaf Farooqi; Julia Keogh; Montague Carl; John Brennand; Lynn Jorde; Nicholas J Wareham; Stephen O'Rahilly
Studies of the neuromedin U-2 receptor gene in human obesity: evidence for the existence of two ancestral forms of the receptor.
The Journal of endocrinology 2004;183(1):115-20.
2004: Shamarina Shohaimi; Sheila Bingham; Ailsa Welch; Robert Luben; Nicholas E Day; Nicholas J Wareham; Kay-Tee Khaw
Occupational social class, educational level and area deprivation independently predict plasma ascorbic acid concentration: a cross-sectional population based study in the Norfolk cohort of the European Prospective Investigation into Cancer (EPIC-Norfolk).
European journal of clinical nutrition 2004;58(10):1432-5.
2004: S Matthijs Boekholdt; Ron J G Peters; Nicholas E Day; Robert Luben; Sheila A Bingham; Nicholas J Wareham; C Erik Hack; Pieter H Reitsma; Kay-Tee Khaw
Macrophage migration inhibitory factor and the risk of myocardial infarction or death due to coronary artery disease in adults without prior myocardial infarction or stroke: the EPIC-Norfolk Prospective Population study.
The American journal of medicine 2004;117(6):390-7.
2004: S Matthijs Boekholdt; Jan Albert Kuivenhoven; Nicholas J Wareham; Ron J G Peters; J Wouter Jukema; Robert Luben; Sheila A Bingham; Nicholas E Day; John J P Kastelein; Kay-Tee Khaw
Plasma levels of cholesteryl ester transfer protein and the risk of future coronary artery disease in apparently healthy men and women: the prospective EPIC (European Prospective Investigation into Cancer and nutrition)-Norfolk population study.
Circulation 2004;110(11):1418-23.
2004: Søren Brage; Niels Wedderkopp; Ulf Ekelund; Paul W Franks; Nicholas J Wareham; Lars Bo Andersen; Karsten Froberg
Features of the metabolic syndrome are associated with objectively measured physical activity and fitness in Danish children: the European Youth Heart Study (EYHS).
Diabetes care 2004;27(9):2141-8.
2004: Chiao-Chien Connie Hung; Fraser Pirie; Jian'an Luan; Emma Lank; Ayesha Motala; Giles S H Yeo; Julia M Keogh; Nicholas J Wareham; Stephen O'Rahilly; I Sadaf Farooqi
Studies of the peptide YY and neuropeptide Y2 receptor genes in relation to human obesity and obesity-related traits.
Diabetes 2004;53(9):2461-6.
2004: Shamarina Shohaimi; Ailsa Welch; Sheila Bingham; Robert Luben; Nicholas E Day; Nicholas J Wareham; Kay-Tee Khaw
Residential area deprivation predicts fruit and vegetable consumption independently of individual educational level and occupational social class: a cross sectional population study in the Norfolk cohort of the European Prospective Investigation into Cancer (EPIC-Norfolk).
Journal of epidemiology and community health 2004;58(8):686-91.
2004: S Matthijs Boekholdt; Ron J G Peters; C Erik Hack; Nicholas E Day; Robert Luben; Sheila A Bingham; Nicholas J Wareham; Pieter H Reitsma; Kay-Tee Khaw
IL-8 plasma concentrations and the risk of future coronary artery disease in apparently healthy men and women: the EPIC-Norfolk prospective population study.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(8):1503-8.
2004: Shamarina Shohaimi; Ailsa Welch; Sheila Bingham; Robert Luben; Nicholas E Day; Nicholas J Wareham; Kay-Tee Khaw
Area deprivation predicts lung function independently of education and social class.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2004;24(1):157-61.
2004: Kevin C J Yuen; Nicholas J Wareham; Jan Frystyk; Susie Hennings; Jo Mitchell; Linda Fryklund; David D Dunger
Short-term low-dose growth hormone administration in subjects with impaired glucose tolerance and the metabolic syndrome: effects on beta-cell function and post-load glucose tolerance.
European journal of endocrinology / European Federation of Endocrine Societies 2004;151(1):39-45.
2004: Dexter Canoy; Robert Luben; Ailsa Welch; Sheila Bingham; Nicholas J Wareham; Nicholas E Day; Kay-Tee Khaw
Abdominal obesity and respiratory function in men and women in the EPIC-Norfolk Study, United Kingdom.
American journal of epidemiology 2004;159(12):1140-9.
2004: Kay-Tee Khaw; Nicholas J Wareham; Sheila Bingham; Robert Luben; Ailsa Welch; Nicholas E Day
Preliminary communication: glycated hemoglobin, diabetes, and incident colorectal cancer in men and women: a prospective analysis from the European prospective investigation into cancer-Norfolk study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2004;13(6):915-9.
2004: Matthew F Yuyun; Kay-Tee Khaw; Robert Luben; Ailsa Welch; Sheila Bingham; Nicholas E Day; Nicholas J Wareham
Microalbuminuria, cardiovascular risk factors and cardiovascular morbidity in a British population: the EPIC-Norfolk population-based study.
European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 2004;11(3):207-13.
2004: Stella George; Justin J Rochford; Christian Wolfrum; Sarah L Gray; Sven Schinner; Jenny C Wilson; Maria A Soos; Peter R Murgatroyd; Rachel M Williams; Carlo L Acerini; David D Dunger; David Barford; A Margot Umpleby; Nicholas J Wareham; Huw Alban Davies; Alan J Schafer; Markus Stoffel; Stephen O'Rahilly; Inês Barroso
A family with severe insulin resistance and diabetes due to a mutation in AKT2.
Science (New York, N.Y.) 2004;304(5675):1325-8.
2004: William T Gibson; Pavlos Pissios; Daniel Trombly; Jian'an Luan; Julia Keogh; Nicholas J Wareham; Eleftheria Maratos-Flier; Stephen O'Rahilly; I Sadaf Farooqi
Melanin-concentrating hormone receptor mutations and human obesity: functional analysis.
Obesity research 2004;12(5):743-9.
2004: Philip B Grace; James I Taylor; Yen-Ling Low; Robert N Luben; Angela A Mulligan; Nigel P Botting; Mitch Dowsett; Ailsa A Welch; Kay-Tee Khaw; Nicholas J Wareham; Nicholas E Day; Sheila A Bingham
Phytoestrogen concentrations in serum and spot urine as biomarkers for dietary phytoestrogen intake and their relation to breast cancer risk in European prospective investigation of cancer and nutrition-norfolk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2004;13(5):698-708.
2004: Paul W Franks; Ulf Ekelund; Søren Brage; Man-Yu Wong; Nicholas J Wareham
Does the association of habitual physical activity with the metabolic syndrome differ by level of cardiorespiratory fitness?
Diabetes care 2004;27(5):1187-93.
2004: Ulf Ekelund; Søren Brage; Nicholas J Wareham
Physical activity in young children.
Lancet 2004;363(9415):1163; author reply 1163-4.
2004: Man-Yu Wong; Nicholas E Day; Jian'an Luan; Nicholas J Wareham
Estimation of magnitude in gene-environment interactions in the presence of measurement error.
Statistics in medicine 2004;23(6):987-98.
2004: Matthias Laudes; Inês Barroso; Jian'an Luan; Maria A Soos; Giles Yeo; Aline Meirhaeghe; Lisa Logie; Antonio Vidal-Puig; Alan J Schafer; Nicholas J Wareham; Stephen O'Rahilly
Genetic variants in human sterol regulatory element binding protein-1c in syndromes of severe insulin resistance and type 2 diabetes.
Diabetes 2004;53(3):842-6.
2004: Benjamin G Challis; Jian'an Luan; Julia Keogh; Nicholas J Wareham; I Sadaf Farooqi; Stephen O'Rahilly
Genetic variation in the corticotrophin-releasing factor receptors: identification of single-nucleotide polymorphisms and association studies with obesity in UK Caucasians.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2004;28(3):442-6.
2004: Matthew F Yuyun; Kay-Tee Khaw; Robert Luben; Ailsa Welch; Sheila Bingham; Nicholas E Day; Nicholas J Wareham
Microalbuminuria independently predicts all-cause and cardiovascular mortality in a British population: The European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) population study.
International journal of epidemiology 2004;33(1):189-98.
2004: Anne-Helen Harding; Nicholas E Day; Kay-Tee Khaw; Sheila A Bingham; Robert N Luben; A Welsh; Nicholas J Wareham
Habitual fish consumption and glycated haemoglobin: the EPIC-Norfolk study.
European journal of clinical nutrition 2004;58(2):277-84.
2004: Matthew F Yuyun; Kay-Tee Khaw; Robert Luben; Ailsa Welch; Sheila Bingham; Nicholas E Day; Nicholas J Wareham
Microalbuminuria and stroke in a British population: the European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) population study.
Journal of internal medicine 2004;255(2):247-56.
2004: Matthew F Yuyun; Kay-Tee Khaw; Robert Luben; Ailsa Welch; Sheila Bingham; Nicholas E Day; Nicholas J Wareham
A prospective study of microalbuminuria and incident coronary heart disease and its prognostic significance in a British population: the EPIC-Norfolk study.
American journal of epidemiology 2004;159(3):284-93.
2004: Paul W Franks; Sumit Bhattacharyya; Jian'an Luan; Montague Carl; John Brennand; Benjamin G Challis; Søren Brage; Ulf Ekelund; Rita P S Middelberg; Stephen O'Rahilly; Nicholas J Wareham
Association between physical activity and blood pressure is modified by variants in the G-protein coupled receptor 10.
Hypertension 2004;43(2):224-8.
2004: Kay-Tee Khaw; Jonathan Reeve; Robert Luben; Sheila Bingham; Ailsa Welch; Nicholas J Wareham; Suzy Oakes; Nicholas E Day
Prediction of total and hip fracture risk in men and women by quantitative ultrasound of the calcaneus: EPIC-Norfolk prospective population study.
Lancet 2004;363(9404):197-202.
2004: David A J Neal; Brian D M Tom; Jian'an Luan; Nicholas J Wareham; Alexander E S Gimson; Luc Delriviere; Christopher D Byrne; Graeme J M Alexander
Is there disparity between risk and incidence of cardiovascular disease after liver transplant?
Transplantation 2004;77(1):93-9.
2004: Manjinder S Sandhu; J Martin Gibson; Adrian H Heald; David D Dunger; Nicholas J Wareham
Association between insulin-like growth factor-I: insulin-like growth factor-binding protein-1 ratio and metabolic and anthropometric factors in men and women.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2004;13(1):166-70.
2004: Annemieke M W Spijkerman; Matthew F Yuyun; Simon J Griffin; Jacqueline M Dekker; Giel Nijpels; Nicholas J Wareham
The performance of a risk score as a screening test for undiagnosed hyperglycemia in ethnic minority groups: data from the 1999 health survey for England.
Diabetes care 2004;27(1):116-22.
2004: Anne-Helen Harding; Nicholas E Day; Kay-Tee Khaw; Sheila Bingham; Robert Luben; Ailsa Welsh; Nicholas J Wareham
Dietary fat and the risk of clinical type 2 diabetes: the European prospective investigation of Cancer-Norfolk study.
American journal of epidemiology 2004;159(1):73-82.
2004: Paul W Franks; Jian'an Luan; P O Browne; Anne-Helen Harding; Stephen O'Rahilly; V Krishna K Chatterjee; Nicholas J Wareham
Does peroxisome proliferator-activated receptor gamma genotype (Pro12ala) modify the association of physical activity and dietary fat with fasting insulin level?
Metabolism: clinical and experimental 2004;53(1):11-6.
2004: Søren Brage; Niels Brage; Paul W Franks; Ulf Ekelund; Man-Yu Wong; Lars Bo Andersen; Karsten Froberg; Nicholas J Wareham
Branched equation modeling of simultaneous accelerometry and heart rate monitoring improves estimate of directly measured physical activity energy expenditure.
Journal of applied physiology (Bethesda, Md. : 1985) 2004;96(1):343-51.
2003: Paul W Franks; Inês Barroso; Jian'an Luan; Ulf Ekelund; Vivion E F Crowley; Søren Brage; Manjinder S Sandhu; Rupert W Jakes; Rita P S Middelberg; Anne-Helen Harding; Alan J Schafer; Stephen O'Rahilly; Nicholas J Wareham
PGC-1alpha genotype modifies the association of volitional energy expenditure with [OV0312]O2max.
Medicine and science in sports and exercise 2003;35(12):1998-2004.
2003: Stephen Kaptoge; Nichola Dalzell; Rupert W Jakes; Nicholas J Wareham; Nicholas E Day; Kay-Tee Khaw; Thomas J Beck; Nigel Loveridge; Jonathan Reeve
Hip section modulus, a measure of bending resistance, is more strongly related to reported physical activity than BMD.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2003;14(11):941-9.
2003: Inês Barroso; Jian'an Luan; Rita P S Middelberg; Anne-Helen Harding; Paul W Franks; Rupert W Jakes; D Clayton; Alan J Schafer; Stephen O'Rahilly; Nicholas J Wareham
Candidate gene association study in type 2 diabetes indicates a role for genes involved in beta-cell function as well as insulin action.
PLoS biology 2003;1(1):E20.
2003: Rupert W Jakes; Nicholas E Day; Kay-Tee Khaw; Robert Luben; Suzy Oakes; Ailsa Welch; Sheila Bingham; Nicholas J Wareham
Television viewing and low participation in vigorous recreation are independently associated with obesity and markers of cardiovascular disease risk: EPIC-Norfolk population-based study.
European journal of clinical nutrition 2003;57(9):1089-96.
2003: Megan R Smith; Ann Louise Kinmonth; Robert N Luben; Sheila Bingham; Nicholas E Day; Nicholas J Wareham; Ailsa Welch; Kay-Tee Khaw
Smoking status and differential white cell count in men and women in the EPIC-Norfolk population.
Atherosclerosis 2003;169(2):331-7.
2003: Paul W Franks; I Sadaf Farooqi; Jian'an Luan; Man-Yu Wong; Ian Halsall; Stephen O'Rahilly; Nicholas J Wareham
Does physical activity energy expenditure explain the between-individual variation in plasma leptin concentrations after adjusting for differences in body composition?
The Journal of clinical endocrinology and metabolism 2003;88(7):3258-63.
2003: Halsall David; Ian McFarlane; Jian'an Luan; Timothy M Cox; Nicholas J Wareham
Typical type 2 diabetes mellitus and HFE gene mutations: a population-based case - control study.
Human molecular genetics 2003;12(12):1361-5.
2003: Nicholas J Wareham; Rupert W Jakes; Kirsten L Rennie; Jantine Schuit; Jo Mitchell; Susie Hennings; Nicholas E Day
Validity and repeatability of a simple index derived from the short physical activity questionnaire used in the European Prospective Investigation into Cancer and Nutrition (EPIC) study.
Public health nutrition 2003;6(4):407-13.
2003: Manjinder S Sandhu; J Martin Gibson; Adrian H Heald; David D Dunger; Nicholas J Wareham
Low circulating IGF-II concentrations predict weight gain and obesity in humans.
Diabetes 2003;52(6):1403-8.
2003: M Rahman; Simon J Griffin; W Rathmann; Nicholas J Wareham
How should peripheral neuropathy be assessed in people with diabetes in primary care? A population-based comparison of four measures.
Diabetic medicine : a journal of the British Diabetic Association 2003;20(5):368-74.
2003: Sumit Bhattacharyya; Jian'an Luan; Benjamin G Challis; Catherine Schmitz; Paul Clarkson; Paul W Franks; Rita P S Middelberg; Julia Keogh; I Sadaf Farooqi; Montague Carl; John Brennand; Nicholas J Wareham; Stephen O'Rahilly
Association of polymorphisms in GPR10, the gene encoding the prolactin-releasing peptide receptor with blood pressure, but not obesity, in a U.K. Caucasian population.
Diabetes 2003;52(5):1296-9.
2003: Chiao-Chien Connie Hung; I Sadaf Farooqi; Ken Ong; Jian'an Luan; Julia M Keogh; Marcus E Pembrey; Giles S H Yeo; David D Dunger; Nicholas J Wareham; Stephen O' Rahilly
Contribution of variants in the small heterodimer partner gene to birthweight, adiposity, and insulin levels: mutational analysis and association studies in multiple populations.
Diabetes 2003;52(5):1288-91.
2003: Matthew F Yuyun; S F Dinneen; O M Edwards; E Wood; Nicholas J Wareham
Absolute level and rate of change of albuminuria over 1 year independently predict mortality and cardiovascular events in patients with diabetic nephropathy.
Diabetic medicine : a journal of the British Diabetic Association 2003;20(4):277-82.
2003: Shamarina Shohaimi; Robert Luben; Nicholas J Wareham; Nicholas E Day; Sheila Bingham; Ailsa Welch; Suzy Oakes; Kay-Tee Khaw
Residential area deprivation predicts smoking habit independently of individual educational level and occupational social class. A cross sectional study in the Norfolk cohort of the European Investigation into Cancer (EPIC-Norfolk).
Journal of epidemiology and community health 2003;57(4):270-6.
2003: Man-Yu Wong; Nicholas E Day; Jian'an Luan; K P Chan; Nicholas J Wareham
The detection of gene-environment interaction for continuous traits: should we deal with measurement error by bigger studies or better measurement?
International journal of epidemiology 2003;32(1):51-7.
2002: Nicholas J Wareham; Paul W Franks; Anne-Helen Harding
Establishing the role of gene-environment interactions in the etiology of type 2 diabetes.
Endocrinology and metabolism clinics of North America 2002;31(3):553-66.
2002: Anne-Helen Harding; Lincoln A Sargeant; Kay-Tee Khaw; Ailsa Welch; Suzy Oakes; Robert N Luben; Sheila Bingham; Nicholas E Day; Nicholas J Wareham
Cross-sectional association between total level and type of alcohol consumption and glycosylated haemoglobin level: the EPIC-Norfolk Study.
European journal of clinical nutrition 2002;56(9):882-90.
2002: Paul W Franks; Man-Yu Wong; Jian'an Luan; Jo Mitchell; Susie Hennings; Nicholas J Wareham
Non-esterified fatty acid levels and physical inactivity: the relative importance of low habitual energy expenditure and cardio-respiratory fitness.
The British journal of nutrition 2002;88(3):307-13.
2002: Benjamin G Challis; Lynn E Pritchard; John W M Creemers; Jerome Delplanque; Julia M Keogh; Jian'an Luan; Nicholas J Wareham; Giles S H Yeo; Sumit Bhattacharyya; philippe froguel; Anne White; I Sadaf Farooqi; Stephen O'Rahilly
A missense mutation disrupting a dibasic prohormone processing site in pro-opiomelanocortin (POMC) increases susceptibility to early-onset obesity through a novel molecular mechanism.
Human molecular genetics 2002;11(17):1997-2004.
2002: David B Savage; Maura Agostini; Inês Barroso; Mark Gurnell; Jian'an Luan; Aline Meirhaeghe; Anne-Helen Harding; Gudrun Ihrke; Odelia Rajanayagam; Maria A Soos; Stella George; Dirk Berger; E Louise Thomas; Jimmy D Bell; Karim Meeran; R J M Ross; Antonio Vidal-Puig; Nicholas J Wareham; Stephen O'Rahilly; V Krishna K Chatterjee; Alan J Schafer
Digenic inheritance of severe insulin resistance in a human pedigree.
Nature genetics 2002;31(4):379-84.
2002: Rupert W Jakes; Nicholas E Day; Bip Patel; Kay-Tee Khaw; Suzy Oakes; Robert Luben; Ailsa Welch; Sheila Bingham; Nicholas J Wareham
Physical inactivity is associated with lower forced expiratory volume in 1 second : European Prospective Investigation into Cancer-Norfolk Prospective Population Study.
American journal of epidemiology 2002;156(2):139-47.
2002: Joanna Poulton; Jian'an Luan; Vincent Macaulay; Susie Hennings; Jo Mitchell; Nicholas J Wareham
Type 2 diabetes is associated with a common mitochondrial variant: evidence from a population-based case-control study.
Human molecular genetics 2002;11(13):1581-3.
2002: P J Park; Simon J Griffin; Lincoln A Sargeant; Nicholas J Wareham
The performance of a risk score in predicting undiagnosed hyperglycemia.
Diabetes care 2002;25(6):984-8.
2002: Manjinder S Sandhu; Adrian H Heald; J Martin Gibson; J Kennedy Cruickshank; David D Dunger; Nicholas J Wareham
Circulating concentrations of insulin-like growth factor-I and development of glucose intolerance: a prospective observational study.
Lancet 2002;359(9319):1740-5.
2002: Nicholas J Wareham; Rupert W Jakes; Kirsten L Rennie; Jo Mitchell; Susie Hennings; Nicholas E Day
Validity and repeatability of the EPIC-Norfolk Physical Activity Questionnaire.
International journal of epidemiology 2002;31(1):168-74.
2002: Annemieke M W Spijkerman; S Griffin; J Dekker; Giel Nijpels; Nicholas J Wareham
What is the risk of mortality for people who are screen positive in a diabetes screening programme but who do not have diabetes on biochemical testing? Diabetes screening programmes from a public health perspective.
Journal of medical screening 2002;9(4):187-90.
2002: Robert Luben; Kay-Tee Khaw; Ailsa Welch; Sheila Bingham; Nicholas J Wareham; Suzy Oakes; Nicholas E Day
Plasma vitamin C, cancer mortality and incidence in men and women: a prospective study.
IARC scientific publications 2002;156():117-8.
2002: Sally D Poppitt; Geraldine Keogh; Andrew M Prentice; Desmond E M Williams; Heidi M W Sonnemans; Esther E J Valk; Elizabeth Robinson; Nicholas J Wareham
Long-term effects of ad libitum low-fat, high-carbohydrate diets on body weight and serum lipids in overweight subjects with metabolic syndrome.
The American journal of clinical nutrition 2002;75(1):11-20.
2001: Nicholas J Wareham
Commentary: Measuring physical activity in Sub-Saharan Africa.
International journal of epidemiology 2001;30(6):1369-70.
2001: Aline Meirhaeghe; Jian'an Luan; P Selberg-Franks; Susie Hennings; Jo Mitchell; Halsall David; Stephen O'Rahilly; Nicholas J Wareham
The effect of the Gly16Arg polymorphism of the beta(2)-adrenergic receptor gene on plasma free fatty acid levels is modulated by physical activity.
The Journal of clinical endocrinology and metabolism 2001;86(12):5881-7.
2001: Anne-Helen Harding; Lincoln A Sargeant; Ailsa Welch; Suzy Oakes; Robert N Luben; Sheila Bingham; Nicholas E Day; Kay-Tee Khaw; Nicholas J Wareham
Fat consumption and HbA(1c) levels: the EPIC-Norfolk study.
Diabetes care 2001;24(11):1911-6.
2001: Jian'an Luan; Man-Yu Wong; Nicholas E Day; Nicholas J Wareham
Sample size determination for studies of gene-environment interaction.
International journal of epidemiology 2001;30(5):1035-40.
2001: Anne-Helen Harding; D E Williams; S H Hennings; J Mitchell; Nicholas J Wareham
Is the association between dietary fat intake and insulin resistance modified by physical activity?
Metabolism: clinical and experimental 2001;50(10):1186-92.
2001: P Maison; Christopher D Byrne; C Nicholas Hales; Nicholas E Day; Nicholas J Wareham
Do different dimensions of the metabolic syndrome change together over time? Evidence supporting obesity as the central feature.
Diabetes care 2001;24(10):1758-63.
2001: Lincoln A Sargeant; Kay-Tee Khaw; Sheila Bingham; Nicholas E Day; Robert N Luben; Suzy Oakes; Ailsa Welch; Nicholas J Wareham
Cigarette smoking and glycaemia: the EPIC-Norfolk Study. European Prospective Investigation into Cancer.
International journal of epidemiology 2001;30(3):547-54.
2001: Sheila A Bingham; Ailsa A Welch; Alison McTaggart; Angela A Mulligan; Shirley A Runswick; Robert Luben; Suzy Oakes; Kay-Tee Khaw; Nicholas J Wareham; Nicholas E Day
Nutritional methods in the European Prospective Investigation of Cancer in Norfolk.
Public health nutrition 2001;4(3):847-58.
2001: Kirsten L Rennie; Susie Hennings; Jo Mitchell; Nicholas J Wareham
Estimating energy expenditure by heart-rate monitoring without individual calibration.
Medicine and science in sports and exercise 2001;33(6):939-45.
2001: Lincoln A Sargeant; Kay-Tee Khaw; Sheila Bingham; Nicholas E Day; Robert N Luben; Suzy Oakes; Ailsa Welch; Nicholas J Wareham
Fruit and vegetable intake and population glycosylated haemoglobin levels: the EPIC-Norfolk Study.
European journal of clinical nutrition 2001;55(5):342-8.
2001: Nicholas J Wareham; Simon J Griffin
Should we screen for type 2 diabetes? Evaluation against National Screening Committee criteria.
BMJ (Clinical research ed.) 2001;322(7292):986-8.
2001: Halsall David; Jian'an Luan; P Saker; S Huxtable; I Sadaf Farooqi; Julia Keogh; Nicholas J Wareham; Stephen O'Rahilly
Uncoupling protein 3 genetic variants in human obesity: the c-55t promoter polymorphism is negatively correlated with body mass index in a UK Caucasian population.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2001;25(4):472-7.
2001: Kay-Tee Khaw; Sheila Bingham; Ailsa Welch; Robert Luben; Nicholas J Wareham; Suzy Oakes; Nicholas E Day
Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
Lancet 2001;357(9257):657-63.
2001: Jian'an Luan; P O Browne; Anne-Helen Harding; Halsall David; Stephen O'Rahilly; V Krishna K Chatterjee; Nicholas J Wareham
Evidence for gene-nutrient interaction at the PPARgamma locus.
Diabetes 2001;50(3):686-9.
2001: Rupert W Jakes; K Khaw; Nicholas E Day; Sheila Bingham; Ailsa Welch; Suzy Oakes; Robert Luben; Nichola Dalzell; Jonathan Reeve; Nicholas J Wareham
Patterns of physical activity and ultrasound attenuation by heel bone among Norfolk cohort of European Prospective Investigation of Cancer (EPIC Norfolk): population based study.
BMJ (Clinical research ed.) 2001;322(7279):140.
2001: Kay-Tee Khaw; Nicholas J Wareham; Robert Luben; Sheila Bingham; Suzy Oakes; Ailsa Welch; Nicholas E Day
Glycated haemoglobin, diabetes, and mortality in men in Norfolk cohort of european prospective investigation of cancer and nutrition (EPIC-Norfolk).
BMJ (Clinical research ed.) 2001;322(7277):15-8.
2000: Lincoln A Sargeant; Nicholas J Wareham; K T Khaw
Family history of diabetes identifies a group at increased risk for the metabolic consequences of obesity and physical inactivity in EPIC-Norfolk: a population-based study. The European Prospective Investigation into Cancer.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2000;24(10):1333-9.
2000: Lincoln A Sargeant; A Jaeckel; Nicholas J Wareham
Interaction of vitamin C with the relation between smoking and obstructive airways disease in EPIC Norfolk. European Prospective Investigation into Cancer and Nutrition.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2000;16(3):397-403.
2000: Halsall David; ND Martensz; J Luan; P Maison; Nicholas J Wareham; C Nicholas Hales; Christopher D Byrne
A common apolipoprotein B signal peptide polymorphism modifies the relation between plasma non-esterified fatty acids and triglyceride concentration in men.
Atherosclerosis 2000;152(1):9-17.
2000: Nicholas J Wareham; Man-Yu Wong; Susie Hennings; Jo Mitchell; Kirsten L Rennie; K Cruickshank; Nicholas E Day
Quantifying the association between habitual energy expenditure and blood pressure.
International journal of epidemiology 2000;29(4):655-60.
2000: Nicholas J Wareham; Man-Yu Wong; Nicholas E Day
Glucose intolerance and physical inactivity: the relative importance of low habitual energy expenditure and cardiorespiratory fitness.
American journal of epidemiology 2000;152(2):132-9.
2000: Lincoln A Sargeant; Nicholas J Wareham; Sheila Bingham; Nicholas E Day; Robert N Luben; Suzy Oakes; Ailsa Welch; Kay-Tee Khaw
Vitamin C and hyperglycemia in the European Prospective Investigation into Cancer--Norfolk (EPIC-Norfolk) study: a population-based study.
Diabetes care 2000;23(6):726-32.
2000: Benjamin G Challis; Giles S H Yeo; I Sadaf Farooqi; Jian'an Luan; S Aminian; Halsall David; Julia M Keogh; Nicholas J Wareham; Stephen O'Rahilly
The CART gene and human obesity: mutational analysis and population genetics.
Diabetes 2000;49(5):872-5.
2000: Simon J Griffin; Paul S Little; C N Hales; Ann Louise Kinmonth; Nicholas J Wareham
Diabetes risk score: towards earlier detection of type 2 diabetes in general practice.
Diabetes/metabolism research and reviews 2000;16(3):164-71.
2000: Kirsten L Rennie; T Rowsell; S A Jebb; D Holburn; Nicholas J Wareham
A combined heart rate and movement sensor: proof of concept and preliminary testing study.
European journal of clinical nutrition 2000;54(5):409-14.
2000: D E Williams; AT Prevost; MJ Whichelow; BD Cox; Nicholas E Day; Nicholas J Wareham
A cross-sectional study of dietary patterns with glucose intolerance and other features of the metabolic syndrome.
The British journal of nutrition 2000;83(3):257-66.
2000: Wendy Hardeman; Simon Griffin; M Johnston; Ann Louise Kinmonth; Nicholas J Wareham
Interventions to prevent weight gain: a systematic review of psychological models and behaviour change methods.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2000;24(2):131-43.
2000: P J Park; Simon J Griffin; Stephen W Duffy; Nicholas J Wareham
The effect of varying the screening interval on false positives and duration of undiagnosed disease in a screening programme for type 2 diabetes.
Journal of medical screening 2000;7(2):91-6.
2000: Lincoln A Sargeant; Nicholas J Wareham; K T Khaw
Hormone replacement therapy and glucose tolerance in EPIC-Norfolk: a population-based study.
Diabetes/metabolism research and reviews 2000;16(1):20-5.
2000: P Maison; Christopher D Byrne; C Nicholas Hales; Nicholas J Wareham
Hypertension and its treatment influence changes in fasting nonesterified fatty acid concentrations: a link between the sympathetic nervous system and the metabolic syndrome?
Metabolism: clinical and experimental 2000;49(1):81-7.
1999: Christopher D Byrne; P Maison; Halsall David; ND Martensz; C Nicholas Hales; Nicholas J Wareham
Cross-sectional but not longitudinal associations between non-esterified fatty acid levels and glucose intolerance and other features of the metabolic syndrome.
Diabetic medicine : a journal of the British Diabetic Association 1999;16(12):1007-15.
1999: A J Gould; D E Williams; C D Byrne; C N Hales; Nicholas J Wareham
Prospective cohort study of the relationship of markers of insulin resistance and secretion with weight gain and changes in regional adiposity.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1999;23(12):1256-61.
1999: Man-Yu Wong; Nicholas E Day; Nicholas J Wareham
Measurement error in epidemiology: the design of validation studies II: bivariate situation.
Statistics in medicine 1999;18(21):2831-45.
1999: Nicholas E Day; Suzy Oakes; Robert Luben; Kay-Tee Khaw; Sheila Bingham; Ailsa Welch; Nicholas J Wareham
EPIC-Norfolk: study design and characteristics of the cohort. European Prospective Investigation of Cancer.
British journal of cancer 1999;80 Suppl 1():95-103.
1999: D E Williams; Nicholas J Wareham; BD Cox; C D Byrne; C N Hales; Nicholas E Day
Frequent salad vegetable consumption is associated with a reduction in the risk of diabetes mellitus.
Journal of clinical epidemiology 1999;52(4):329-35.
1999: Nicholas J Wareham; Christopher D Byrne; R Williams; Nicholas E Day; C Nicholas Hales
Fasting proinsulin concentrations predict the development of type 2 diabetes.
Diabetes care 1999;22(2):262-70.
1998: Kirsten L Rennie; Nicholas J Wareham
The validation of physical activity instruments for measuring energy expenditure: problems and pitfalls.
Public health nutrition 1998;1(4):265-71.
1998: Nicholas J Wareham; Susie Hennings; Christopher D Byrne; C Nicholas Hales; Andrew M Prentice; Nicholas E Day
A quantitative analysis of the relationship between habitual energy expenditure, fitness and the metabolic cardiovascular syndrome.
The British journal of nutrition 1998;80(3):235-41.
1998: Christopher D Byrne; Nicholas J Wareham; ND Martensz; S E Humphries; J C Metcalfe; David J Grainger
Increased PAI activity and PAI-1 antigen occurring with an oral fat load: associations with PAI-1 genotype and plasma active TGF-beta levels.
Atherosclerosis 1998;140(1):45-53.
1998: Nicholas J Wareham; Kirsten L Rennie
The assessment of physical activity in individuals and populations: why try to be more precise about how physical activity is assessed?
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1998;22 Suppl 2():S30-8.
1997: Nicholas J Wareham; Susie Hennings; Andrew M Prentice; Nicholas E Day
Feasibility of heart-rate monitoring to estimate total level and pattern of energy expenditure in a population-based epidemiological study: the Ely Young Cohort Feasibility Study 1994-5.
The British journal of nutrition 1997;78(6):889-900.
1997: Christopher D Byrne; Nicholas J Wareham; David Phillips; C Nicholas Hales; ND Martensz
Is an exaggerated postprandial triglyceride response associated with the component features of the insulin resistance syndrome?
Diabetic medicine : a journal of the British Diabetic Association 1997;14(11):942-50.
1997: Nicholas J Wareham; Christopher D Byrne; C Carr; Nicholas E Day; B J Boucher; C Nicholas Hales
Glucose intolerance is associated with altered calcium homeostasis: a possible link between increased serum calcium concentration and cardiovascular disease mortality.
Metabolism: clinical and experimental 1997;46(10):1171-7.
1997: Montague Carl; I Sadaf Farooqi; Jonathan P Whitehead; Maria A Soos; H Rau; Nicholas J Wareham; Ciaran Sewter; JE Digby; S N Mohammed; J A Hurst; C H Cheetham; A R Earley; A H Barnett; Johannes B Prins; Stephen O'Rahilly
Congenital leptin deficiency is associated with severe early-onset obesity in humans.
Nature 1997;387(6636):903-8.
1997: Nicholas J Wareham
Experience in Manitoba with a population-based health information system.
Journal of health services research & policy 1997;2(2):126-8.
1997: F K Zaidi; Nicholas J Wareham; Mark I McCarthy; J Holdstock; H Kalloo-Hosein; A Krook; Robert Swinn; Stephen O'Rahilly
Homozygosity for a common polymorphism in the islet-specific promoter of the glucokinase gene is associated with a reduced early insulin response to oral glucose in pregnant women.
Diabetic medicine : a journal of the British Diabetic Association 1997;14(3):228-34.
1997: Christopher D Byrne; Nicholas J Wareham; C N Hales
The role of insulin and proinsulin in the regulation of triglyceride metabolism.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 1997;105 Suppl 2():29-35.
1996: Nicholas J Wareham; E M Ness; Christopher D Byrne; BD Cox; Nicholas E Day; C Nicholas Hales
Cigarette smoking is not associated with hyperinsulinemia: evidence against a causal relationship between smoking and insulin resistance.
Metabolism: clinical and experimental 1996;45(12):1551-6.
1996: Christopher D Byrne; Nicholas J Wareham; P K Mistry; David Phillips; ND Martensz; Halsall David; P J Talmud; S E Humphries; C Nicholas Hales
The association between free fatty acid concentrations and triglyceride-rich lipoproteins in the post-prandial state is altered by a common deletion polymorphism of the apo B signal peptide.
Atherosclerosis 1996;127(1):35-42.
1996: G Mohan; B D W Harrison; R M Badminton; S Mildenhall; Nicholas J Wareham
A confidential enquiry into deaths caused by asthma in an English health region: implications for general practice.
The British journal of general practice : the journal of the Royal College of General Practitioners 1996;46(410):529-32.
1996: S Rota; P D Flynn; Nicholas J Wareham; Trevor P Baglin; Christopher D Byrne
Is platelet phospholipid-dependent thrombin generation altered by acute myocardial infarction or aspirin?
Thrombosis research 1996;83(4):329-38.
1995: Christopher D Byrne; Nicholas J Wareham; Nicholas E Day; R McLeish; D R Williams; C Nicholas Hales
Decreased non-esterified fatty acid suppression and features of the insulin resistance syndrome occur in a sub-group of individuals with normal glucose tolerance.
Diabetologia 1995;38(11):1358-66.
1995: Nicholas J Wareham; David Phillips; Christopher D Byrne; C N Hales
The 30 minute insulin incremental response in an oral glucose tolerance test as a measure of insulin secretion.
Diabetic medicine : a journal of the British Diabetic Association 1995;12(10):931.
1995: Nicholas J Wareham; Christopher D Byrne; C Nicholas Hales
Role of insulin and proinsulin in diabetic vascular disease.
Metabolism: clinical and experimental 1995;44(10 Suppl 4):76-82.
1995: R A Swinn; Nicholas J Wareham; R Gregory; V Curling; P M Clark; K J Dalton; O M Edwards; Stephen O'Rahilly
Excessive secretion of insulin precursors characterizes and predicts gestational diabetes.
Diabetes 1995;44(8):911-5.
1995: D R Williams; Nicholas J Wareham; D C Brown; Christopher D Byrne; P M Clark; BD Cox; L J Cox; Nicholas E Day; C Nicholas Hales; Christopher R Palmer
Undiagnosed glucose intolerance in the community: the Isle of Ely Diabetes Project.
Diabetic medicine : a journal of the British Diabetic Association 1995;12(1):30-5.
1994: Christopher D Byrne; Nicholas J Wareham; D C Brown; P M Clark; L J Cox; Nicholas E Day; Christopher R Palmer; T W Wang; D R Williams; C Nicholas Hales
Hypertriglyceridaemia in subjects with normal and abnormal glucose tolerance: relative contributions of insulin secretion, insulin resistance and suppression of plasma non-esterified fatty acids.
Diabetologia 1994;37(9):889-96.
1993: Nicholas J Wareham; B D W Harrison; P F Jenkins; J Nicholls; D E Stableforth
A district confidential enquiry into deaths due to asthma.
Thorax 1993;48(11):1117-20.