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Kishor Wasan

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
20
Ramaswamy, Manisha
16
Sivak, Olena
16
Pritchard, Haydn
16
Lopez-Berestein, Gabriel
13
Risovic, Verica
12
Sachs-Barrable, Kristina
9
Lee, Stephen
7
Cassidy, SM
7
Kwong, Mona
7
Thornton, Sheila
7
Procyshyn, Ric
7
Leon, Carlos
6
Rossignol, Daniel
6
Bartlett, Karen
6
Lynn, Melvyn

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Publications

TOP 3
Henderson Ryan J; Leon Carlos G; Wasan Kishor M
Differences in human phospholipid transfer protein activity following incubation of Fungizone compared to lipid-based Amphotericin-B formulations in normolipidemic and hyperlipidemic plasma.
Wasan Kishor M; Wasan Ellen K; Gershkovich Pavel; Zhu Xiaohua; Tidwell Richard R; Werbovetz Karl A; Clement John G; Thornton Sheila J
Highly effective oral amphotericin B formulation against murine visceral leishmaniasis.
Tory Rita; Sachs-Barrable Kristina; Goshko Caylee-Britt; Hill John S; Wasan Kishor M
Tacrolimus-induced elevation in plasma triglyceride concentrations after administration to renal transplant patients is partially due to a decrease in lipoprotein lipase activity and plasma concentrations.

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All Publications

2009: Henderson Ryan J; Leon Carlos G; Wasan Kishor M
Differences in human phospholipid transfer protein activity following incubation of Fungizone compared to lipid-based Amphotericin-B formulations in normolipidemic and hyperlipidemic plasma.
Drug development and industrial pharmacy 2009;35(9):1139-46.
2009: Wasan Kishor M; Wasan Ellen K; Gershkovich Pavel; Zhu Xiaohua; Tidwell Richard R; Werbovetz Karl A; Clement John G; Thornton Sheila J
Highly effective oral amphotericin B formulation against murine visceral leishmaniasis.
The Journal of infectious diseases 2009;200(3):357-60.
2009: Tory Rita; Sachs-Barrable Kristina; Goshko Caylee-Britt; Hill John S; Wasan Kishor M
Tacrolimus-induced elevation in plasma triglyceride concentrations after administration to renal transplant patients is partially due to a decrease in lipoprotein lipase activity and plasma concentrations.
Transplantation 2009;88(1):62-8.
2009: Gershkovich Pavel; Wasan Ellen K; Lin Molly; Sivak Olena; Leon Carlos G; Clement John G; Wasan Kishor M
Pharmacokinetics and biodistribution of amphotericin B in rats following oral administration in a novel lipid-based formulation.
The Journal of antimicrobial chemotherapy 2009;64(1):101-8.
2009: Gershkovich Pavel; Darlington Jerry; Sivak Olena; Constantinides Panayiotis P; Wasan Kishor M
Inhibition of intestinal absorption of cholesterol by surface-modified nanostructured aluminosilicate compounds.
Journal of pharmaceutical sciences 2009;98(7):2390-400.
2009: Patel Jigar P; Fleischer Jackie G; Wasan Kishor M; Brocks Dion R
The effect of experimental hyperlipidemia on the stereoselective tissue distribution, lipoprotein association and microsomal metabolism of (+/-)-halofantrine.
Journal of pharmaceutical sciences 2009;98(7):2516-28.
2009: Wasan Ellen K; Bartlett Karen; Gershkovich Pavel; Sivak Olena; Banno Brian; Wong Zhao; Gagnon Jeffrey; Gates Byron; Leon Carlos G; Wasan Kishor M
Development and characterization of oral lipid-based Amphotericin B formulations with enhanced drug solubility, stability and antifungal activity in rats infected with Aspergillus fumigatus or Candida albicans.
International journal of pharmaceutics 2009;372(1-2):76-84.
2009: Bertrand Nicolas; Fleischer Jackie G; Wasan Kishor M; Leroux Jean-Christophe
Pharmacokinetics and biodistribution of N-isopropylacrylamide copolymers for the design of pH-sensitive liposomes.
Biomaterials 2009;30(13):2598-605.
2009: Thornton Sheila J; Wasan Kishor M
The reformulation of amphotericin B for oral administration to treat systemic fungal infections and visceral leishmaniasis.
Expert opinion on drug delivery 2009;6(3):271-84.
2009: Wasan Kishor M; Thornton Sheila J; Bell Ian; Goulding Rebecca E; Gretes Michael; Gray Andrew P; Hancock Robert E W; Campbell Barbara
The global access initiative at the University of British Columbia (UBC): Availability of UBC discoveries and technologies to the developing world.
Journal of pharmaceutical sciences 2009;98(3):791-4.
2009: Letchford Kevin; Liggins Richard; Wasan Kishor M; Burt Helen
In vitro human plasma distribution of nanoparticulate paclitaxel is dependent on the physicochemical properties of poly(ethylene glycol)-block-poly(caprolactone) nanoparticles.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2009;71(2):196-206.
2009: Wasan Kishor M
The biological functions of lipid excipients and the implications for pharmaceutical products development.
Journal of pharmaceutical sciences 2009;98(2):379-82.
2009: Sivak Olena; Darlington Jerry; Gershkovich Pavel; Constantinides Panayiotis P; Wasan Kishor M
Protonated nanostructured aluminosilicate (NSAS) reduces plasma cholesterol concentrations and atherosclerotic lesions in Apolipoprotein E deficient mice fed a high cholesterol and high fat diet.
Lipids in health and disease 2009;8():30.
2009: Henderson Ryan J; Wasan Kishor M; Leon Carlos G
Haptoglobin inhibits phospholipid transfer protein activity in hyperlipidemic human plasma.
Lipids in health and disease 2009;8():27.
2008: Fielding David W; Brazeau Gayle A; Wasan Kishor M
Introduction to the international pharmacy education supplement.
American journal of pharmaceutical education 2008;72(6):126.
2008: Barta Cheri A; Sachs-Barrable Kristina; Feng Florina; Wasan Kishor M
Effects of monoglycerides on P-glycoprotein: modulation of the activity and expression in Caco-2 cell monolayers.
Molecular pharmaceutics 2008;5(5):863-75.
2008: Leon Carlos G; Tory Rita; Jia Jessica; Sivak Olena; Wasan Kishor M
Discovery and development of toll-like receptor 4 (TLR4) antagonists: a new paradigm for treating sepsis and other diseases.
Pharmaceutical research 2008;25(8):1751-61.
2008: Tory Rita; Sachs-Barrable Kristina; Hill John S; Wasan Kishor M
Cyclosporine A and Rapamycin induce in vitro cholesteryl ester transfer protein activity, and suppress lipoprotein lipase activity in human plasma.
International journal of pharmaceutics 2008;358(1-2):219-23.
2008: Leon Carlos; Jia Jessica; Qiu Guosong; Hill John S; Wasan Kishor M
Modifications in low-density lipoprotein receptor expression affects Cyclosporin A cellular uptake and cytotoxicity.
Journal of pharmaceutical sciences 2008;97(6):2350-61.
2008: Porter Christopher J H; Wasan Kishor M; Constantinides Panayiotis
Lipid-based systems for the enhanced delivery of poorly water soluble drugs.
Advanced drug delivery reviews 2008;60(6):615-6.
2008: Sachs-Barrable Kristina; Lee Stephen D; Wasan Ellen K; Thornton Sheila J; Wasan Kishor M
Enhancing drug absorption using lipids: a case study presenting the development and pharmacological evaluation of a novel lipid-based oral amphotericin B formulation for the treatment of systemic fungal infections.
Advanced drug delivery reviews 2008;60(6):692-701.
2008: Wasan Kishor M; Brocks Dion R; Lee Stephen D; Sachs-Barrable Kristina; Thornton Sheila J
Impact of lipoproteins on the biological activity and disposition of hydrophobic drugs: implications for drug discovery.
Nature reviews. Drug discovery 2008;7(1):84-99.
2008: Locke Jennifer A; Wasan Kishor M; Nelson Colleen C; Guns Emma S; Leon Carlos G
Androgen-mediated cholesterol metabolism in LNCaP and PC-3 cell lines is regulated through two different isoforms of acyl-coenzyme A:Cholesterol Acyltransferase (ACAT).
The Prostate 2008;68(1):20-33.
2008: Wasan Kishor M; Risovic Verica; Sivak Olena; Lee Stephen D; Mason Douglas X; Chiklis Gregory R; McShane Jim; Lynn Melvyn; Wong Nancy; Rossignol Daniel P
Influence of plasma cholesterol and triglyceride concentrations and eritoran (E5564) micelle size on its plasma pharmacokinetics and ex vivo activity following single intravenous bolus dose into healthy female rabbits.
Pharmaceutical research 2008;25(1):176-82.
2008: Gershkovich Pavel; Wasan Kishor M; Barta Cheri A
A review of the application of lipid-based systems in systemic, dermal/ transdermal, and ocular drug delivery.
Critical reviews in therapeutic drug carrier systems 2008;25(6):545-84.
2008: Jia Jessica X; Wasan Kishor M
Effects of monoglycerides on rhodamine 123 accumulation, estradiol 17 beta-D-glucuronide bidirectional transport and MRP2 protein expression within Caco-2 cells.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques 2008;11(3):45-62.
2008: Thornton Sheila J; Wong Evelyn; Lee Stephen D; Wasan Kishor M
Effect of dietary fat on hepatic liver X receptor expression in P-glycoprotein deficient mice: implications for cholesterol metabolism.
Lipids in health and disease 2008;7():21.
2007: Barta Cheri A; Sachs-Barrable Kristina; Jia Jessica; Thompson Katherine H; Wasan Kishor M; Orvig Chris
Lanthanide containing compounds for therapeutic care in bone resorption disorders.
Dalton transactions (Cambridge, England : 2003) 2007;(43):5019-30.
2007: Low Jonathan C; Wasan Kishor M; Fazli Ladan; Eberding Andy; Adomat Hans; Guns Emma S
Assessing the therapeutic and toxicological effects of cesium chloride following administration to nude mice bearing PC-3 or LNCaP prostate cancer xenografts.
Cancer chemotherapy and pharmacology 2007;60(6):821-9.
2007: Rosland Micheal; Szeto Priscilla; Procyshyn Ric; Barr Alasdair M; Wasan Kishor M
Determination of clozapine and its metabolite, norclozapine in various biological matrices using high-performance liquid chromatography.
Drug development and industrial pharmacy 2007;33(10):1158-66.
2007: Thornton Sheila J; Warburton Corinna; Wasan Kishor M; Kozlowski Piotr
Treatment with a cholesterol absorption inhibitor (FM-VP4) reduces body mass and adipose accumulation in developing and pre-obese mice.
Drug development and industrial pharmacy 2007;33(10):1058-69.
2007: Procyshyn Ric M; Wasan Kishor M; Thornton Allen E; Barr Alasdair M; Chen Eric Y H; Pomarol-Clotet Edith; Stip Emmanuel; Williams Richard; Macewan G William; Birmingham C Laird; Honer William G;
Changes in serum lipids, independent of weight, are associated with changes in symptoms during long-term clozapine treatment.
Journal of psychiatry & neuroscience : JPN 2007;32(5):331-8.
2007: Stoodley Robin; Wasan Kishor M; Bizzotto Dan
Fluorescence of amphotericin B-deoxycholate (fungizone) monomers and aggregates and the effect of heat-treatment.
Langmuir : the ACS journal of surfaces and colloids 2007;23(17):8718-25.
2007: Risovic Verica; Rosland Mike; Sivak Olena; Wasan Kishor M; Bartlett Karen
Assessing the antifungal activity of a new oral lipid-based amphotericin B formulation following administration to rats infected with Aspergillus fumigatus.
Drug development and industrial pharmacy 2007;33(7):703-7.
2007: Wasan Kishor M; Sivak Olena; Rosland Michael; Risovic Verica; Bartlett Karen
Assessing the antifungal activity, pharmacokinetics, and tissue distribution of amphotericin B following the administration of Abelcet and AmBisome in combination with caspofungin to rats infected with Aspergillus fumigatus.
Journal of pharmaceutical sciences 2007;96(7):1737-47.
2007: Shayeganpour Anooshirvan; Lee Stephen D; Wasan Kishor M; Brocks Dion R
The influence of hyperlipoproteinemia on in vitro distribution of amiodarone and desethylamiodarone in human and rat plasma.
Pharmaceutical research 2007;24(4):672-8.
2007: Beauchesne Pascal R; Chung Nancy S C; Wasan Kishor M
Cyclosporine A: a review of current oral and intravenous delivery systems.
Drug development and industrial pharmacy 2007;33(3):211-20.
2007: Dhanikula Anand Babu; Khalid Nabil Mohamed; Lee Stephen D; Yeung Rosanna; Risovic Verica; Wasan Kishor M; Leroux Jean-Christophe
Long circulating lipid nanocapsules for drug detoxification.
Biomaterials 2007;28(6):1248-57.
2007: Constantinides Panayiotis P; Wasan Kishor M
Lipid formulation strategies for enhancing intestinal transport and absorption of P-glycoprotein (P-gp) substrate drugs: in vitro/in vivo case studies.
Journal of pharmaceutical sciences 2007;96(2):235-48.
2007: Sachs-Barrable Kristina; Thamboo Andrea; Lee Stephen D; Wasan Kishor M
Lipid excipients Peceol and Gelucire 44/14 decrease P-glycoprotein mediated efflux of rhodamine 123 partially due to modifying P-glycoprotein protein expression within Caco-2 cells.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques 2007;10(3):319-31.
2006: Leon C; Sachs-Barrable K; Wasan K M
Does p-glycoprotein play a role in gastrointestinal absorption and cellular transport of dietary cholesterol?
Drug development and industrial pharmacy 2006;32(6):779-82.
2006: Leon Carlos; Wasan Kishor M; Sachs-Barrable Kristina; Johnston Thomas P
Acute P-407 administration to mice causes hypercholesterolemia by inducing cholesterolgenesis and down-regulating low-density lipoprotein receptor expression.
Pharmaceutical research 2006;23(7):1597-607.
2006: Risovic Verica; Man Damen; Sivak Olena; Lee Stephen D; Wasan Kishor M
Assessing lipid lowering and plasma cholesteryl ester transfer protein activity of simvastatin following administration to rabbits fed a high fat/cholesterol diet.
Drug development and industrial pharmacy 2006;32(5):609-15.
2006: Lee S D; Wasan K M; Calcagni A; Avery M; McCush F; Chen C
The in vitro plasma distribution of a novel cholesteryl ester transfer protein inhibitor, torcetrapib, is influenced by differences in plasma lipid concentrations.
Pharmaceutical research 2006;23(5):1025-30.
2006: Patankar Nilesh; Wasan Kishor M
Role of phospholipid transfer protein on the plasma distribution of amphotericin B following the incubation of different amphotericin B formulations.
Pharmaceutical research 2006;23(5):1020-4.
2006: Johnston Thomas P; Jaye Michael; Webb Christine L; Krawiec John A; Alom-Ruiz Sara Pilar; Sachs-Barrable Kristina; Wasan Kishor M
Poloxamer 407 (P-407)-mediated reduction in the gene expression of ATP-binding-cassette transporter A1 may contribute to increased cholesterol in peripheral tissues of P-407-treated rats.
European journal of pharmacology 2006;536(3):232-40.
2006: Honer William G; Thornton Allen E; Chen Eric Y H; Chan Raymond C K; Wong Jessica O Y; Bergmann Andrea; Falkai Peter; Pomarol-Clotet Edith; McKenna Peter J; Stip Emmanuel; Williams Richard; MacEwan G William; Wasan Kishor; Procyshyn Ric;
Clozapine alone versus clozapine and risperidone with refractory schizophrenia.
The New England journal of medicine 2006;354(5):472-82.
2006: Wasan Kishor M; Wong Joyce C; Corr Traci; Pritchard Sheila
Role of plasma lipids and lipoproteins in predicting amphotericin B-induced nephrotoxicity in pediatric oncology patients.
Cancer chemotherapy and pharmacology 2006;57(1):120-4.
2006: Wasan Kishor M; Risovic Verica; Yuen Violet G; McNeill John H
Differences in plasma homocysteine levels between Zucker fatty and Zucker diabetic fatty rats following 3 weeks oral administration of organic vanadium compounds.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2006;19(4):251-8.
2005: Procyshyn Ric M; Ho Tiffany; Wasan Kishor M
The effects of competitive displacement on haloperidol's plasma distribution in normolipidemic and hyperlipidemic plasma.
Drug development and industrial pharmacy 2005;31(9):901-5.
2005: Leon Carlos; Hill John S; Wasan Kishor M
Potential role of acyl-coenzyme A:cholesterol transferase (ACAT) Inhibitors as hypolipidemic and antiatherosclerosis drugs.
Pharmaceutical research 2005;22(10):1578-88.
2005: Leon Carlos; Taylor Ross; Bartlett Karen H; Wasan Kishor M
Effect of heat-treatment and the role of phospholipases on Fungizone-induced cytotoxicity within human kidney proximal tubular (HK-2) cells and Aspergillus fumigatus.
International journal of pharmaceutics 2005;298(1):211-8.
2005: Procyshyn Ric M; Ho Tiffany; Wasan Kishor M
Competitive displacement of clozapine from plasma proteins in normolipidemic and hyperlipidemic plasma samples: clinical implications.
Drug development and industrial pharmacy 2005;31(4-5):331-7.
2005: Chung Nancy S; Sachs-Barrable Kristina; Lee Stephen D; Wasan Kishor M
Suitability of LLC-PK1 pig kidney cells for the study of drug action on renal cell cholesterol uptake: identification and characterization of low-density lipoprotein receptors.
Journal of pharmacological and toxicological methods 2005;51(2):139-45.
2005: Looije Norbert A; Risovic Verica; Stewart David J; Debeyer Daniel; Kutney James; Wasan Kishor M
Disodium Ascorbyl Phytostanyl Phosphates (FM-VP4) reduces plasma cholesterol concentration, body weight and abdominal fat gain within a dietary-induced obese mouse model.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques 2005;8(3):400-8.
2005: Wasan Kishor M; Looije Norbert A
Emerging pharmacological approaches to the treatment of obesity.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques 2005;8(2):259-71.
2005: Ng Agatha W K; Wasan Kishor M; Lopez-Berestein Gabriel
Liposomal polyene antibiotics.
Methods in enzymology 2005;391():304-13.
2004: Sivak Olena; Lau Benny; Patankar Nilesh; Wasan Kishor M
Unidirectional inhibition of lipid transfer protein I-mediated transfer of cholesteryl esters between high-density and low-density lipoproteins by amphotericin B lipid complex.
Pharmaceutical research 2004;21(12):2336-9.
2004: Sivak Olena; Bartlett Karen; Wasan Kishor M
Heat-treated Fungizone retains amphotericin B antifungal activity without renal toxicity in rats infected with Aspergillus fumigatus.
Pharmaceutical research 2004;21(9):1564-6.
2004: van Raalte Daniel H; Li Min; Pritchard P Haydn; Wasan Kishor M
Peroxisome proliferator-activated receptor (PPAR)-alpha: a pharmacological target with a promising future.
Pharmaceutical research 2004;21(9):1531-8.
2004: Rossignol Daniel P; Wasan Kishor M; Choo Eugene; Yau Edwin; Wong Nancy; Rose Jeffrey; Moran Jeffrey; Lynn Melvyn
Safety, pharmacokinetics, pharmacodynamics, and plasma lipoprotein distribution of eritoran (E5564) during continuous intravenous infusion into healthy volunteers.
Antimicrobial agents and chemotherapy 2004;48(9):3233-40.
2004: Risovic Verica; Sachs-Barrable Kristina; Boyd Michael; Wasan Kishor M
Potential mechanisms by which Peceol increases the gastrointestinal absorption of amphotericin B.
Drug development and industrial pharmacy 2004;30(7):767-74.
2004: Ng Agatha W K; Lukic Tatjana; Pritchard P Haydn; Wasan Kishor M
Development and characterization of liposomal disodium ascorbyl phytostanyl phosphates (FM-VP4).
Drug development and industrial pharmacy 2004;30(7):739-58.
2004: Wasan Kishor M; Choo Eugene; Sivak Olena; Wallis Simon; Letchford Kevin; Burt Helen M; Stewart David J; Lukic Tatjana
Determining the critical micelle concentration of a novel lipid-lowering agent, disodium ascorbyl phytostanyl phosphate (FM-VP4), using a fluorescence depolarization procedure.
Drug development and industrial pharmacy 2004;30(7):725-30.
2004: Sivak Olena; Bartlett Karen; Risovic Verica; Choo Eugene; Marra Fawziah; Batty D Scotty; Wasan Kishor M
Assessing the antifungal activity and toxicity profile of amphotericin B lipid complex (ABLC; Abelcet) in combination with caspofungin in experimental systemic aspergillosis.
Journal of pharmaceutical sciences 2004;93(6):1382-9.
2004: Chung Nancy S; Wasan Kishor M
Potential role of the low-density lipoprotein receptor family as mediators of cellular drug uptake.
Advanced drug delivery reviews 2004;56(9):1315-34.
2004: Liang Linda S; Jackson John; Min Weixian; Risovic Verica; Wasan Kishor M; Burt Helen M
Methotrexate loaded poly(L-lactic acid) microspheres for intra-articular delivery of methotrexate to the joint.
Journal of pharmaceutical sciences 2004;93(4):943-56.
2004: Boyd Michael; Risovic Verica; Jull Philip; Choo Eugene; Wasan Kishor M
A stepwise surgical procedure to investigate the lymphatic transport of lipid-based oral drug formulations: Cannulation of the mesenteric and thoracic lymph ducts within the rat.
Journal of pharmacological and toxicological methods 2004;49(2):115-20.
2004: Bartlett Karen; Yau Edwin; Hartsel Scott C; Hamer Alison; Tsai Gina; Bizzotto Dan; Wasan Kishor M
Effect of heat-treated amphotericin B on renal and fungal cytotoxicity.
Antimicrobial agents and chemotherapy 2004;48(1):333-6.
2004: Lynn Melvyn; Wong Y Nancy; Wheeler Janice L; Kao Richard J; Perdomo Carlos A; Noveck Robert; Vargas Ramon; D'Angelo Tony; Gotzkowsky Sandra; McMahon F Gilbert; Wasan Kishor M; Rossignol Daniel P
Extended in vivo pharmacodynamic activity of E5564 in normal volunteers with experimental endotoxemia [corrected].
The Journal of pharmacology and experimental therapeutics 2004;308(1):175-81.
2004: Wasan Kishor M; Risovic Verica; Yuen Violet G; Hicke Alan; McNeill John H
Effects of three and eight weeks oral administration of bis(maltolato)oxovanadium(IV) on plasma homocysteine and cysteine levels in streptozotocin-induced diabetic rats.
Experimental and clinical cardiology 2004;9(2):125-9.
2003: Risovic Verica; Boyd Michael; Choo Eugene; Wasan Kishor M
Effects of lipid-based oral formulations on plasma and tissue amphotericin B concentrations and renal toxicity in male rats.
Antimicrobial agents and chemotherapy 2003;47(10):3339-42.
2003: Kim Taekrho; Callahan Shellie M; Wasan Kishor M; Brunner Lane J
Effect of high-density lipoprotein associated cyclosporine on hepatic metabolism and renal function.
PDA journal of pharmaceutical science and technology / PDA 2003;57(5):341-50.
2003: Subramanian Ramaswamy; Wasan Kishor M
Effect of lipid excipients on in vitro pancreatic lipase activity.
Drug development and industrial pharmacy 2003;29(8):885-90.
2003: Wasan Kishor M; Sivak Olena; Cote Richard A; MacInnes Aaron I; Boulanger Kathy D; Lynn Melvyn; Christ William J; Hawkins Lynn D; Rossignol Daniel P
Association of the endotoxin antagonist E5564 with high-density lipoproteins in vitro: dependence on low-density and triglyceride-rich lipoprotein concentrations.
Antimicrobial agents and chemotherapy 2003;47(9):2796-803.
2003: Kwong Mona; Wasan Kishor M
Cyclosporine binds to the neutral lipid and potentially other binding sites of lipid transfer protein I.
Pharmaceutical research 2003;20(7):1009-14.
2003: Wasan Kishor M; Subramanian Ramaswamy; Kwong Mona; Goldberg Ira J; Wright Thamrah; Johnston Thomas P
Poloxamer 407-mediated alterations in the activities of enzymes regulating lipid metabolism in rats.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques 2003;6(2):189-97.
2003: Lukic Tatjana; Wasan Kishor M; Zamfir Daniela; Moghadasian Mohammed H; Pritchard P Haydn
Disodium ascorbyl phytostanyl phosphate reduces plasma cholesterol concentrations and atherosclerotic lesion formation in apolipoprotein E-deficient mice.
Metabolism: clinical and experimental 2003;52(4):425-31.
2003: Wasan Kishor M; Zamfir Catalina; Pritchard P Haydn; Pederson Raymond A
Influence of phytostanol phosphoryl ascorbate (FM-VP4) on insulin resistance, hyperglycemia, plasma lipid levels, and gastrointestinal absorption of exogenous cholesterol in Zucker (fa/fa) fatty and lean rats.
Journal of pharmaceutical sciences 2003;92(2):281-8.
2003: Subramanian Ramaswamy; Ramaswamy Manisha; Wasan Kishor M
Role of lipid and lipoprotein metabolizing enzymes in the development of atherosclerosis.
Indian journal of experimental biology 2003;41(1):14-25.
2003: Ng Agatha W K; Wasan Kishor M; Lopez-Berestein Gabriel
Development of liposomal polyene antibiotics: an historical perspective.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques 2003;6(1):67-83.
2003: Wasan Kishor M; Sivak Olena
Modifications in lipoprotein surface charge alter cyclosporine A association with low-density lipoproteins.
Pharmaceutical research 2003;20(1):126-9.
2003: Procyshyn Ric M; Tsai Gina; Wasan Kishor M
The influence of dyslipidemia on the plasma protein and lipoprotein distribution of haloperidol.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2003;13(1):33-7.
2003: Ng Agatha W K; Lukic Tatjana; Pritchard P Haydn; Wasan Kishor M
Development of novel water-soluble phytostanol analogs: disodium ascorbyl phytostanyl phosphates (FM-VP4): preclinical pharmacology, pharmacokinetics and toxicology.
Cardiovascular drug reviews 2003;21(3):151-68.
2003: Wasan Kishor M; Yau Edwin; Boulanger Kathy D; Ramswamy Manisha; Pritchard P Haydn
Effects of disodium ascorbyl phytostanol phosphates (FM-VP4) on cholesterol accumulation within rat intestinal cells.
AAPS pharmSci 2003;5(1):E6.
2002: Kwong Mona; Wasan Kishor M
Cholesteryl ester transfer protein facilitates the movement of water-insoluble drugs between lipoproteins: a novel biological function for a well-characterized lipid transfer protein.
Biochemical pharmacology 2002;64(12):1669-75.
2002: Wasan Kishor M; Donnachie Elizabeth M; Seccombe David W; Pritchard P Haydn
Effect of cyclosporine A on the binding affinity and internalization of low-density lipoproteins in human skin fibroblasts.
Journal of pharmaceutical sciences 2002;91(12):2520-4.
2002: Wasan Kishor M
The role of lymphatic transport in enhancing oral protein and peptide drug delivery.
Drug development and industrial pharmacy 2002;28(9):1047-58.
2002: Brocks Dion R; Wasan Kishor M
The influence of lipids on stereoselective pharmacokinetics of halofantrine: Important implications in food-effect studies involving drugs that bind to lipoproteins.
Journal of pharmaceutical sciences 2002;91(8):1817-26.
2002: Stoodley R; Shepherd J; Wasan K M; Bizzotto D
Amphotericin B interactions with a DOPC monolayer. Electrochemical investigations.
Biochimica et biophysica acta 2002;1564(1):289-97.
2002: Wasan Ellen K; Waterhouse Dawn; Sivak Olena; Bally Marcel B; Klasa Richard J; Wasan Kishor M
Plasma protein binding, lipoprotein distribution and uptake of free and lipid-associated BCL-2 antisense oligodeoxynucleotides (G3139) in human melanoma cells.
International journal of pharmaceutics 2002;241(1):57-64.
2002: Amin Ketan; Wasan Kishor M; Albrecht Ralph M; Heath Timothy D
Cell association of liposomes with high fluid anionic phospholipid content is mediated specifically by LDL and its receptor, LDLr.
Journal of pharmaceutical sciences 2002;91(5):1233-44.
2002: Ramaswamy Manisha; Yau Edwin; Wasan Kishor M; Boulanger Kathy D; Li Ming; Pritchard P Haydn
Influence of phytostanol phosphoryl ascorbate, FM-VP4, on pancreatic lipase activity and cholesterol accumulation within Caco-2 cells.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques 2002;5(1):29-38.
2002: Marra Fawziah; Partovi Nilufar; Wasan Kishor M; Kwong Evan H; Ensom Mary H H; Cassidy Shawn M; Fradet Guy; Levy Robert D
Amphotericin B disposition after aerosol inhalation in lung transplant recipients.
The Annals of pharmacotherapy 2002;36(1):46-51.
2002: Wasan Kishor M; Ramaswamy Manisha; Kwong Mona; Boulanger Kathy D
Role of plasma lipoproteins in modifying the toxic effects of water-insoluble drugs: studies with cyclosporine A.
AAPS pharmSci 2002;4(4):E30.
2001: Wasan K M; Najafi S; Peteherych K D; Pritchard P H
Effects of a novel hydrophilic phytostanol analog on plasma lipid concentrations in gerbils.
Journal of pharmaceutical sciences 2001;90(11):1795-9.
2001: Peteherych K D; Wasan K M
Effects of lipoproteins on cyclosporine A toxicity and uptake in LLC-PK1 pig kidney cells.
Journal of pharmaceutical sciences 2001;90(9):1395-406.
2001: Kwong M; Sivak O; Kwong E H; Wasan K M
Cyclosporine A transfer between high- and low-density lipoproteins: independent from lipid transfer protein I-facilitated transfer of lipoprotein-coated phospholipids because of high affinity of cyclosporine a for the protein component of lipoproteins.
Journal of pharmaceutical sciences 2001;90(9):1308-17.
2001: Wasan K M; Najafi S; Wong J; Kwong M; Pritchard P H
Assessing plasma lipid levels, body weight, and hepatic and renal toxicity following chronic oral administration of a water soluble phytostanol compound, FM-VP4, to gerbils.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques 2001;4(3):228-34.
2001: Wasan K M; Peteherych K D; Najafi S; Zamfir C; Pritchard P H
Assessing the plasma pharmacokinetics, tissue distribution, excretion and effects on cholesterol pharmacokinetics of a novel hydrophilic compound, FM-VP4, following administration to rats.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques 2001;4(3):207-16.
2001: Ramaswamy M; Wasan K M
Differences in the method by which plasma is separated from whole blood influences amphotericin B plasma recovery and distribution following amphotericin B lipid complex incubation within whole blood.
Drug development and industrial pharmacy 2001;27(8):871-5.
2001: Hartsel S C; Bauer E; Kwong E H; Wasan K M
The effect of serum albumin on amphotericin B aggregate structure and activity.
Pharmaceutical research 2001;18(9):1305-9.
2001: Kwong E H; Ramaswamy M; Bauer E A; Hartsel S C; Wasan K M
Heat treatment of amphotericin b modifies its serum pharmacokinetics, tissue distribution, and renal toxicity following administration of a single intravenous dose to rabbits.
Antimicrobial agents and chemotherapy 2001;45(7):2060-3.
2001: Procyshyn R M; Kennedy N B; Marriage S; Wasan K M
Plasma protein and lipoprotein distribution of clozapine.
The American journal of psychiatry 2001;158(6):949-51.
2001: Wasan K M; Ramaswamy M; Holtorf L; Jayaraj A A; Hauss D J
Rat and rabbit plasma distribution of free and chylomicron-associated BIRT 377, a novel small molecule antagonist of LFA-1-mediated cell adhesion.
Pharmaceutical research 2001;18(4):510-9.
2001: Wasan K M
Formulation and physiological and biopharmaceutical issues in the development of oral lipid-based drug delivery systems.
Drug development and industrial pharmacy 2001;27(4):267-76.
2001: Ramaswamy M; Peteherych K D; Kennedy A L; Wasan K M
Amphotericin B lipid complex or amphotericin B multiple-dose administration to rabbits with elevated plasma cholesterol levels: pharmacokinetics in plasma and blood, plasma lipoprotein levels, distribution in tissues, and renal toxicities.
Antimicrobial agents and chemotherapy 2001;45(4):1184-91.
2001: Hartsel S C; Baas B; Bauer E; Foree L T; Kindt K; Preis H; Scott A; Kwong E H; Ramaswamy M; Wasan K M
Heat-induced superaggregation of amphotericin B modifies its interaction with serum proteins and lipoproteins and stimulation of TNF-alpha.
Journal of pharmaceutical sciences 2001;90(2):124-33.
2001: Wasan K M; Holtorf L; Subramanian R; Cassidy S M; Pritchard P H; Stewart D J; Novak E; Moghadasian M H
Assessing plasma pharmacokinetics of cholesterol following oral coadministration with a novel vegetable stanol mixture to fasting rats.
Journal of pharmaceutical sciences 2001;90(1):23-8.
2000: Rose J R; Mullarkey M A; Christ W J; Hawkins L D; Lynn M; Kishi Y; Wasan K M; Peteherych K; Rossignol D P
Consequences of interaction of a lipophilic endotoxin antagonist with plasma lipoproteins.
Antimicrobial agents and chemotherapy 2000;44(3):504-10.
1999: Kennedy A L; Wasan K M
Preferential distribution of amphotericin B lipid complex into human HDL3 is a consequence of high density lipoprotein coat lipid content.
Journal of pharmaceutical sciences 1999;88(11):1149-55.
1999: Wasan K M; Strobel F W; Parrott S C; Lynn M; Christ W J; Hawkins L D; Rossignol D P
Lipoprotein distribution of a novel endotoxin antagonist, E5531, in plasma from human subjects with various lipid levels.
Antimicrobial agents and chemotherapy 1999;43(10):2562-4.
1999: Wasan K M; Subramanian R; Chou J W; Ramaswamy M; Pritchard P H
Cyclosporine transfer from low- and high-density lipoproteins is partially influenced by lipid transfer protein I triglyceride transfer activity.
Pharmaceutical research 1999;16(7):1067-73.
1999: Ramaswamy M; Wallace T L; Cossum P A; Wasan K M
Species differences in the proportion of plasma lipoprotein lipid carried by high-density lipoproteins influence the distribution of free and liposomal nystatin in human, dog, and rat plasma.
Antimicrobial agents and chemotherapy 1999;43(6):1424-8.
1999: McIntosh M P; Porter C J; Wasan K M; Ramaswamy M; Charman W N
Differences in the lipoprotein binding profile of halofantrine in fed and fasted human or beagle plasma are dictated by the respective masses of core apolar lipoprotein lipid.
Journal of pharmaceutical sciences 1999;88(3):378-84.
1999: Wasan K M; Ramaswamy M; McIntosh M P; Porter C J; Charman W N
Differences in the lipoprotein distribution of halofantrine are regulated by lipoprotein apolar lipid and protein concentration and lipid transfer protein I activity: in vitro studies in normolipidemic and dyslipidemic human plasmas.
Journal of pharmaceutical sciences 1999;88(2):185-90.
1999: Wasan K M; Cassidy S M; Ramaswamy M; Kennedy A; Strobel F W; Ng S P; Lee T Y
A comparison of step-gradient and sequential density ultracentrifugation and the use of lipoprotein deficient plasma controls in determining the plasma lipoprotein distribution of lipid-associated nystatin and cyclosporine.
Pharmaceutical research 1999;16(1):165-9.
1998: Wasan K M; Kennedy A L; Cassidy S M; Ramaswamy M; Holtorf L; Chou J W; Pritchard P H
Pharmacokinetics, distribution in serum lipoproteins and tissues, and renal toxicities of amphotericin B and amphotericin B lipid complex in a hypercholesterolemic rabbit model: single-dose studies.
Antimicrobial agents and chemotherapy 1998;42(12):3146-52.
1998: Wasan K M; Ng S P; Wong W; Rodrigues B B
Streptozotocin- and alloxan-induced diabetes modifies total plasma and lipoprotein lipid concentration and composition without altering cholesteryl ester transfer activity.
Pharmacology & toxicology 1998;83(4):169-75.
1998: Cassidy S M; Strobel F W; Wasan K M
Plasma lipoprotein distribution of liposomal nystatin is influenced by protein content of high-density lipoproteins.
Antimicrobial agents and chemotherapy 1998;42(8):1878-88.
1998: Wasan K M; Ramaswamy M; Ng S P; Wong W; Parrott S C; Ojwang J O; Wallace T; Cossum P A
Differences in the lipoprotein distribution of free and liposome-associated all-trans-retinoic acid in human, dog, and rat plasma are due to variations in lipoprotein lipid and protein content.
Antimicrobial agents and chemotherapy 1998;42(7):1646-53.
1998: Wasan K M; Cassidy S M
Role of plasma lipoproteins in modifying the biological activity of hydrophobic drugs.
Journal of pharmaceutical sciences 1998;87(4):411-24.
1998: Wasan K M; Ramaswamy M; Wong W; Pritchard P H
Lipid transfer protein I facilitated transfer of cyclosporine from low- to high-density lipoproteins is only partially dependent on its cholesteryl ester transfer activity.
The Journal of pharmacology and experimental therapeutics 1998;284(2):599-605.
1997: Wasan K M; Pritchard P H; Ramaswamy M; Wong W; Donnachie E M; Brunner L J
Differences in lipoprotein lipid concentration and composition modify the plasma distribution of cyclosporine.
Pharmaceutical research 1997;14(11):1613-20.
1997: Wasan K M; Ramaswamy M; Cassidy S M; Kazemi M; Strobel F W; Thies R L
Physical characteristics and lipoprotein distribution of liposomal nystatin in human plasma.
Antimicrobial agents and chemotherapy 1997;41(9):1871-5.
1997: Wasan K M; Ramaswamy M; Haley J; Dunn B P
Administration of long-term tamoxifen therapy modifies the plasma lipoprotein-lipid concentration and lipid transfer protein I activity in postmenopausal women with breast cancer.
Journal of pharmaceutical sciences 1997;86(7):876-9.
1997: Wasan K M; Ng S; Cassidy S M
Modifications in high-density lipoprotein lipid composition and structure alter the plasma distribution of free and liposomal annamycin.
Journal of pharmaceutical sciences 1997;86(7):872-5.
1997: Wasan K M; Kwong M
Blood and plasma lipoprotein distribution and gender differences in the plasma pharmacokinetics of lipid-associated annamycin.
Pharmacology & toxicology 1997;80(6):301-7.
1997: Ramaswamy M; Zhang X; Burt H M; Wasan K M
Human plasma distribution of free paclitaxel and paclitaxel associated with diblock copolymers.
Journal of pharmaceutical sciences 1997;86(4):460-4.
1997: Wasan K M; Lopez-Berestein G
Diversity of lipid-based polyene formulations and their behavior in biological systems.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 1997;16(1):81-92.
1997: Wasan K M; Conklin J S
Enhanced amphotericin B nephrotoxicity in intensive care patients with elevated levels of low-density lipoprotein cholesterol.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1997;24(1):78-80.
1996: Wasan K M; Lopez-Berestein G
Characteristics of lipid-based formulations that influence their biological behavior in the plasma of patients.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1996;23(5):1126-38.
1996: Wasan K M; Conklin J S
Evaluation of renal toxicity and antifungal activity of free and liposomal amphotericin B following a single intravenous dose to diabetic rats with systemic candidiasis.
Antimicrobial agents and chemotherapy 1996;40(8):1806-10.
1996: Vadiei K; Tucker S D; Lopez-Berestein G; Wasan K M
Nephroprotective mechanism(s) of pentoxifylline: reduction of erythrocyte-mediated vascular congestion and inhibition of nitric oxide release.
Pharmacology & toxicology 1996;78(3):174-80.
1996: Wasan K M; Morton R E
Differences in lipoprotein concentration and composition modify the plasma distribution of free and liposomal annamycin.
Pharmaceutical research 1996;13(3):462-8.
1995: Wasan K M; Perez-Soler R
Distribution of free and liposomal annamycin within human plasma is regulated by plasma triglyceride concentrations but not by lipid transfer protein.
Journal of pharmaceutical sciences 1995;84(9):1094-100.
1995: Wasan K M; Grossie V B
Effect of intralipid infusion on serum high- and low-density lipoprotein cholesterol, lecithin:cholesterol acyltransferase, and lipoprotein lipase in tumor-bearing rats.
Experientia 1995;51(3):230-4.
1994: Wasan K M; Grossie V B; Lopez-Berestein G
Concentrations in serum and distribution in tissue of free and liposomal amphotericin B in rats during continuous intralipid infusion.
Antimicrobial agents and chemotherapy 1994;38(9):2224-6.
1994: Wasan K M; Morton R E; Rosenblum M G; Lopez-Berestein G
Decreased toxicity of liposomal amphotericin B due to association of amphotericin B with high-density lipoproteins: role of lipid transfer protein.
Journal of pharmaceutical sciences 1994;83(7):1006-10.
1994: Wasan K M; Hayman A C; Lopez-Berestein G
Determination of dimyristoylphosphatidylglycerol in human serum by liquid-liquid extraction and reversed-phase liquid chromatography.
Journal of pharmaceutical and biomedical analysis 1994;12(6):851-4.
1994: Wasan K M; Grossie V B; Lopez-Berestein G
Effects of intralipid infusion on rat serum lipoproteins.
Laboratory animals 1994;28(2):138-42.
1994: Wasan K M; Rosenblum M G; Cheung L; Lopez-Berestein G
Influence of lipoproteins on renal cytotoxicity and antifungal activity of amphotericin B.
Antimicrobial agents and chemotherapy 1994;38(2):223-7.
1993: Wasan K M; Brazeau G A; Keyhani A; Hayman A C; Lopez-Berestein G
Roles of liposome composition and temperature in distribution of amphotericin B in serum lipoproteins.
Antimicrobial agents and chemotherapy 1993;37(2):246-50.
1991: Wasan K M; Vadiei K; Luke D R; Keyhani A; White R A; McQueen T J; Mehta R; Lopez-Berestein G
Antifungal activity of HWA-138 and amphotericin B in experimental systemic candidiasis.
Antimicrobial agents and chemotherapy 1991;35(10):2046-8.
1991: Berens K L; Langston J D; Wasan K M; Luke D R
Influence of pentoxifylline and related analogues in endotoxemic renal failure.
Circulatory shock 1991;34(3):344-8.
1991: Luke D R; Wasan K M; Verani R R; Brunner L J; Berens K L; Vadiei K; Lopez-Berestein G
Attenuation of amphotericin-B nephrotoxicity in the candidiasis rat model.
Nephron 1991;59(1):139-44.
1991: Luke D R; Wasan K M; Vadiei K
Circadian variation in renal function of the obese rat.
Renal physiology and biochemistry 1991;14(1-2):71-80.
1990: Langston J D; Wasan K M; Lopez-Berestein G; Verani R R; Luke D R
Evaluation of amphotericin B-cyclosporine interaction in the rat.
Transplantation 1990;50(3):506-10.
1990: Luke D R; Wasan K M; McQueen T J; Lopez-Berestein G
Enhancement of the treatment of experimental candidiasis with vascular decongestants.
The Journal of infectious diseases 1990;162(1):211-4.
1990: Berens K L; Vadiei K; Brunner L J; Wasan K M; Luke D R
Influence of lovastatin on the pharmacokinetics, toxicity and immunologic response of cyclosporine in the obese Zucker rat.
Biopharmaceutics & drug disposition 1990;11(3):197-206.
1990: Wasan K M; Vadiei K; Lopez-Berestein G; Luke D R
Pharmacokinetics, tissue distribution, and toxicity of free and liposomal amphotericin B in diabetic rats.
The Journal of infectious diseases 1990;161(3):562-6.
1990: Wasan K M; Vadiei K; Lopez-Berestein G; Verani R R; Luke D R
Pentoxifylline in amphotericin B toxicity rat model.
Antimicrobial agents and chemotherapy 1990;34(2):241-4.
1990: Brunner L J; Wasan K M; Vadiei K; Berens K L; Luke D R
Impact of time and feeding habits on lipid levels in Zucker obese rats.
Progress in clinical and biological research 1990;341B():195-201.
1990: Wasan K M; Meltzer A; Luke D R
Serum cholinesterase (CE) activity and lipid levels in hyperlipidemic rats.
Progress in clinical and biological research 1990;341A():193-8.
1990: Luke D R; Wasan K M; Vadiei K
Lack of circadian variation in renal function in the obese rat: influence of continuous food and water intake.
Progress in clinical and biological research 1990;341A():131-6.
1989: Wasan K M; Brunner L J; Berens K L; Meltzer A A; Luke D R
Circadian assessment of lipids in the hyperphagic obese rat compared with lean litter-mates.
Chronobiology international 1989;6(3):223-8.

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