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Cristina Wasowski

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Cristina Wasowski; Josefina Higgs; Leonardo M Loscalzo; Mariel Marder
Chronic intraperitoneal and oral treatments with hesperidin induce central nervous system effects in mice.
Leonardo M Loscalzo; Cristina Wasowski; Tin T Yow; Mary Chebib; Mariel Marder
Hesperidin induces antinociceptive effect in mice and its aglycone, hesperetin, binds to μ-opioid receptor and inhibits GIRK1/2 currents.
Cristina Wasowski; Mariel Marder
Central nervous system activities of two diterpenes isolated from Aloysia virgata.

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All Publications

2012: Cristina Wasowski; Josefina Higgs; Leonardo M Loscalzo; Mariel Marder
Chronic intraperitoneal and oral treatments with hesperidin induce central nervous system effects in mice.
Phytotherapy research : PTR 2012;26(2):308-12.
2011: Leonardo M Loscalzo; Cristina Wasowski; Tin T Yow; Mary Chebib; Mariel Marder
Hesperidin induces antinociceptive effect in mice and its aglycone, hesperetin, binds to μ-opioid receptor and inhibits GIRK1/2 currents.
Pharmacology, biochemistry, and behavior 2011;99(3):333-41.
2011: Cristina Wasowski; Mariel Marder
Central nervous system activities of two diterpenes isolated from Aloysia virgata.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2011;18(5):393-401.
2009: Leonardo M Loscalzo; Cristina Wasowski; Mariel Marder
Neuroactive flavonoid glycosides from Tilia petiolaris DC. extracts.
Phytotherapy research : PTR 2009;23(10):1453-7.
2009: M Cecilia Martínez; Sebastian P Fernandez; Leonardo M Loscalzo; Cristina Wasowski; Alejandro C Paladini; Mariel Marder; Jorge H Medina; Haydée Viola
Hesperidin, a flavonoid glycoside with sedative effect, decreases brain pERK1/2 levels in mice.
Pharmacology, biochemistry, and behavior 2009;92(2):291-6.
2008: Roman Furtmueller; Birgit Furtmueller; Joachim Ramerstorfer; Alejandro C Paladini; Cristina Wasowski; Mariel Marder; Sigismund Huck; Werner Sieghart
6,3'-Dinitroflavone is a low efficacy modulator of GABA(A) receptors.
European journal of pharmacology 2008;591(1-3):142-6.
2008: Leonardo M Loscalzo; Cristina Wasowski; Alejandro C Paladini; Mariel Marder
Opioid receptors are involved in the sedative and antinociceptive effects of hesperidin as well as in its potentiation with benzodiazepines.
European journal of pharmacology 2008;580(3):306-13.
2006: Sebastián P Fernández; Cristina Wasowski; Leonardo M Loscalzo; Renee E Granger; Graham A R Johnston; Alejandro C Paladini; Mariel Marder
Central nervous system depressant action of flavonoid glycosides.
European journal of pharmacology 2006;539(3):168-76.
2006: MC Hellión-Ibarrola; DA Ibarrola; Y Montalbetti; M L Kennedy; O Heinichen; M Campuzano; Jaime Tortoriello; Sebastián P Fernández; Cristina Wasowski; Mariel Marder; T C M De Lima; Sergio Mora
The anxiolytic-like effects of Aloysia polystachya (Griseb.) Moldenke (Verbenaceae) in mice.
Journal of ethnopharmacology 2006;105(3):400-8.
2005: Sebastián P Fernández; Cristina Wasowski; Alejandro C Paladini; Mariel Marder
Synergistic interaction between hesperidin, a natural flavonoid, and diazepam.
European journal of pharmacology 2005;512(2-3):189-98.
2004: Sebastián P Fernández; Cristina Wasowski; Alejandro C Paladini; Mariel Marder
Sedative and sleep-enhancing properties of linarin, a flavonoid-isolated from Valeriana officinalis.
Pharmacology, biochemistry, and behavior 2004;77(2):399-404.
2003: Mariel Marder; Haydée Viola; Cristina Wasowski; Sebastián P Fernández; Jorge H Medina; Alejandro C Paladini
6-methylapigenin and hesperidin: new valeriana flavonoids with activity on the CNS.
Pharmacology, biochemistry, and behavior 2003;75(3):537-45.
2002: Cristina Wasowski; Mariel Marder; Haydée Viola; Jorge H Medina; Alejandro C Paladini
Isolation and identification of 6-methylapigenin, a competitive ligand for the brain GABA(A) receptors, from Valeriana wallichii.
Planta medica 2002;68(10):934-6.
2001: Mariel Marder; G Estiú; L B Blanch; Haydée Viola; Cristina Wasowski; Jorge H Medina; Alejandro C Paladini
Molecular modeling and QSAR analysis of the interaction of flavone derivatives with the benzodiazepine binding site of the GABA(A) receptor complex.
Bioorganic & medicinal chemistry 2001;9(2):323-35.
2000: Haydée Viola; Mariel Marder; Cristina Wasowski; O Giorgi; Alejandro C Paladini; Jorge H Medina
6,3'-dibromoflavone and 6-nitro-3'-bromoflavone: new additions to the 6,3'-disubstituted flavone family of high-affinity ligands of the brain benzodiazepine binding site with agonistic properties.
Biochemical and biophysical research communications 2000;273(2):694-8.
2000: Haydée Viola; C Wolfman; Mariel Marder; Juan D Goutman; M Bianchin; Cristina Wasowski; Daniel J Calvo; Iván Izquierdo; Alejandro C Paladini; Jorge H Medina
6-Chloro-3'-nitroflavone is a potent ligand for the benzodiazepine binding site of the GABA(A) receptor devoid of intrinsic activity.
Pharmacology, biochemistry, and behavior 2000;65(2):313-20.
1999: Haydée Viola; Mariel Marder; J Nuñez; Luciana A Izquierdo; Cristina Wasowski; C Wolfman; Patrícia Ardenghi; Daniela M Barros; Jorge H Medina; Alejandro C Paladini
6-Methyl-3'-bromoflavone, a high-affinity ligand for the benzodiazepine binding site of the GABA(A) receptor with some antagonistic properties.
Biochemical and biophysical research communications 1999;262(3):643-6.
1999: Alejandro C Paladini; Mariel Marder; Haydée Viola; C Wolfman; Cristina Wasowski; Jorge H Medina
Flavonoids and the central nervous system: from forgotten factors to potent anxiolytic compounds.
The Journal of pharmacy and pharmacology 1999;51(5):519-26.
1998: C Wolfman; Haydée Viola; Mariel Marder; Patrícia Ardenghi; Cristina Wasowski; Nadja Schröder; Iván Izquierdo; Edmundo A Rúveda; Alejandro C Paladini; Jorge H Medina
Pharmacological characterization of 6-bromo-3'-nitroflavone, a synthetic flavonoid with high affinity for the benzodiazepine receptors.
Pharmacology, biochemistry, and behavior 1998;61(3):239-46.
1998: Mariel Marder; Haydée Viola; J A Bacigaluppo; María I Colombo; Cristina Wasowski; C Wolfman; Jorge H Medina; Edmundo A Rúveda; Alejandro C Paladini
Detection of benzodiazepine receptor ligands in small libraries of flavone derivatives synthesized by solution phase combinatorial chemistry.
Biochemical and biophysical research communications 1998;249(2):481-5.
1998: J H Medina; Daniel J Calvo; Mariel Marder; Haydée Viola; Cristina Wasowski; C Wolfman; A C Paladini
Neuroactive flavonoids: new ligands for the Benzodiazepine receptors.
Phytomedicine : international journal of phytotherapy and phytopharmacology 1998;5(3):235-43.
1997: Jorge H Medina; Haydée Viola; C Wolfman; Mariel Marder; Cristina Wasowski; Daniel J Calvo; Alejandro C Paladini
Overview--flavonoids: a new family of benzodiazepine receptor ligands.
Neurochemical research 1997;22(4):419-25.
1997: Haydée Viola; Cristina Wasowski; C Wolfman; Mariel Marder; A C Paladini; J H Medina
Sedative and hypnotic properties of Salvia guaranitica St. Hil. and of its active principle, Cirsiliol.
Phytomedicine : international journal of phytotherapy and phytopharmacology 1997;4(1):47-52.
1996: C Wolfman; Haydée Viola; Mariel Marder; Cristina Wasowski; Patrícia Ardenghi; Iván Izquierdo; Alejandro C Paladini; Jorge H Medina
Anxioselective properties of 6,3'-dinitroflavone, a high-affinity benzodiazepine receptor ligand.
European journal of pharmacology 1996;318(1):23-30.
1996: Mariel Marder; Haydée Viola; Cristina Wasowski; C Wolfman; P G Waterman; B K Cassels; J G Medina; Alejandro C Paladini
6-Bromoflavone, a high affinity ligand for the central benzodiazepine receptors is a member of a family of active flavonoids.
Biochemical and biophysical research communications 1996;223(2):384-9.
1996: Mariel Marder; J H Medina; Haydée Viola; Cristina Wasowski; P G Waterman; C Wolfman; A C Paladini
Cirsiliol and caffeic acid ethyl ester, isolated from Salvia guaranitica, are competitive ligands for the central benzodiazepine receptors.
Phytomedicine : international journal of phytotherapy and phytopharmacology 1996;3(1):29-31.
1995: Haydée Viola; Cristina Wasowski; Miguelina Levi de Stein; C Wolfman; R Silveira; Federico Dajas; Jorge H Medina; Alejandro C Paladini
Apigenin, a component of Matricaria recutita flowers, is a central benzodiazepine receptors-ligand with anxiolytic effects.
Planta medica 1995;61(3):213-6.
1994: Haydée Viola; C Wolfman; Miguelina Levi de Stein; Cristina Wasowski; Clara Peña; Jorge H Medina; Alejandro C Paladini
Isolation of pharmacologically active benzodiazepine receptor ligands from Tilia tomentosa (Tiliaceae).
Journal of ethnopharmacology 1994;44(1):47-53.
1993: Jorge H Medina; Miguelina Levi de Stein; C Wolfman; Cristina Wasowski; A De Blas; Alejandro C Paladini
In vivo formation of benzodiazepine-like molecules in mammalian brain.
Biochemical and biophysical research communications 1993;195(2):1111-8.
1992: Jorge H Medina; Clara Peña; M Piva; C Wolfman; M L de Stein; Cristina Wasowski; C Da Cunha; Iván Izquierdo; Alejandro C Paladini
Benzodiazepines in the brain. Their origin and possible biological roles.
Molecular neurobiology 1992;6(4):377-86.
1991: Jorge H Medina; J L Danelon; Cristina Wasowski; Miguelina Levi de Stein; Alejandro C Paladini
Production of benzodiazepine-like compounds in bovine rumen.
Biochemical and biophysical research communications 1991;181(3):1048-55.