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Martin Brand

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Dickon M Humphrey; Janne Toivonen; Maria Giannakou; Linda Partridge; Martin D Brand
Expression of human uncoupling protein-3 in Drosophila insulin-producing cells increases insulin-like peptide (DILP) levels and shortens lifespan.
Adrian J Lambert; Martin D Brand
Reactive oxygen species production by mitochondria.
Charles Affourtit; Martin D Brand
Measuring mitochondrial bioenergetics in INS-1E insulinoma cells.

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2009: Dickon M Humphrey; Janne Toivonen; Maria Giannakou; Linda Partridge; Martin D Brand
Expression of human uncoupling protein-3 in Drosophila insulin-producing cells increases insulin-like peptide (DILP) levels and shortens lifespan.
Experimental gerontology 2009;44(5):316-27.
2009: Adrian J Lambert; Martin D Brand
Reactive oxygen species production by mitochondria.
Methods in molecular biology (Clifton, N.J.) 2009;554():165-81.
2009: Charles Affourtit; Martin D Brand
Measuring mitochondrial bioenergetics in INS-1E insulinoma cells.
Methods in enzymology 2009;457():405-24.
2008: Vian Azzu; Charles Affourtit; Eamon P Breen; Nadeene Parker; Martin D Brand
Dynamic regulation of uncoupling protein 2 content in INS-1E insulinoma cells.
Biochimica et biophysica acta 2008;1777(10):1378-83.
2008: Vian Azzu; Nadeene Parker; Martin D Brand
High membrane potential promotes alkenal-induced mitochondrial uncoupling and influences adenine nucleotide translocase conformation.
The Biochemical journal 2008;413(2):323-32.
2008: Charles Affourtit; Martin D Brand
On the role of uncoupling protein-2 in pancreatic beta cells.
Biochimica et biophysica acta 2008;1777(7-8):973-9.
2008: Adrian J Lambert; Julie A Buckingham; Martin D Brand
Dissociation of superoxide production by mitochondrial complex I from NAD(P)H redox state.
FEBS letters 2008;582(12):1711-4.
2008: Nadeene Parker; Charles Affourtit; Antonio Vidal-Puig; Martin D Brand
Energization-dependent endogenous activation of proton conductance in skeletal muscle mitochondria.
The Biochemical journal 2008;412(1):131-9.
2008: Adrian J Lambert; Julie A Buckingham; Helen M Boysen; Martin D Brand
Diphenyleneiodonium acutely inhibits reactive oxygen species production by mitochondrial complex I during reverse, but not forward electron transport.
Biochimica et biophysica acta 2008;1777(5):397-403.
2008: Nadeene Parker; Antonio Vidal-Puig; Martin D Brand
Stimulation of mitochondrial proton conductance by hydroxynonenal requires a high membrane potential.
Bioscience reports 2008;28(2):83-8.
2008: Taku Amo; Nagendra Yadava; Richard Oh; David G Nicholls; Martin D Brand
Experimental assessment of bioenergetic differences caused by the common European mitochondrial DNA haplogroups H and T.
Gene 2008;411(1-2):69-76.
2008: Charles Affourtit; Martin D Brand
Uncoupling protein-2 contributes significantly to high mitochondrial proton leak in INS-1E insulinoma cells and attenuates glucose-stimulated insulin secretion.
The Biochemical journal 2008;409(1):199-204.
2007: Phing-How Lou; Birgit S Hansen; Preben H Olsen; Søren Tullin; Michael P Murphy; Martin D Brand
Mitochondrial uncouplers with an extraordinary dynamic range.
The Biochemical journal 2007;407(1):129-40.
2007: Adrian J Lambert; Helen M Boysen; Julie A Buckingham; Ting Yang; Andrej Podlutsky; Steven Austad; Thomas H Kunz; Rochelle Buffenstein; Martin D Brand
Low rates of hydrogen peroxide production by isolated heart mitochondria associate with long maximum lifespan in vertebrate homeotherms.
Aging cell 2007;6(5):607-18.
2007: Augustine Ocloo; Irina Shabalina; Jan Nedergaard; Martin D Brand
Cold-induced alterations of phospholipid fatty acyl composition in brown adipose tissue mitochondria are independent of uncoupling protein-1.
American journal of physiology. Regulatory, integrative and comparative physiology 2007;293(3):R1086-93.
2007: Adrian J Lambert; Martin D Brand
Research on mitochondria and aging, 2006-2007.
Aging cell 2007;6(4):417-20.
2007: Taku Amo; Martin D Brand
Were inefficient mitochondrial haplogroups selected during migrations of modern humans? A test using modular kinetic analysis of coupling in mitochondria from cybrid cell lines.
The Biochemical journal 2007;404(2):345-51.
2007: Charles Affourtit; Paul G Crichton; Nadeene Parker; Martin D Brand
Novel uncoupling proteins.
Novartis Foundation symposium 2007;287():70-80; discussion 80-91.
2007: Karim S Echtay; Martin D Brand
4-hydroxy-2-nonenal and uncoupling proteins: an approach for regulation of mitochondrial ROS production.
Redox report : communications in free radical research 2007;12(1):26-9.
2006: Frances H Blaikie; Stephanie E Brown; Linda M Samuelsson; Martin D Brand; Robin A J Smith; Michael P Murphy
Targeting dinitrophenol to mitochondria: limitations to the development of a self-limiting mitochondrial protonophore.
Bioscience reports 2006;26(3):231-43.
2006: Telma C Esteves; Nadeene Parker; Martin D Brand
Synergy of fatty acid and reactive alkenal activation of proton conductance through uncoupling protein 1 in mitochondria.
The Biochemical journal 2006;395(3):619-28.
2006: Charles Affourtit; Martin D Brand
Stronger control of ATP/ADP by proton leak in pancreatic beta-cells than skeletal muscle mitochondria.
The Biochemical journal 2006;393(Pt 1):151-9.
2005: Martin D Brand; Julian L Pakay; Augustine Ocloo; Jason Kokoszka; Douglas C Wallace; Paul S Brookes; Emma J Cornwall
The basal proton conductance of mitochondria depends on adenine nucleotide translocase content.
The Biochemical journal 2005;392(Pt 2):353-62.
2005: Martin D Brand
The efficiency and plasticity of mitochondrial energy transduction.
Biochemical Society transactions 2005;33(Pt 5):897-904.
2005: Satomi Miwa; Martin D Brand
The topology of superoxide production by complex III and glycerol 3-phosphate dehydrogenase in Drosophila mitochondria.
Biochimica et biophysica acta 2005;1709(3):214-9.
2005: Darren A Talbot; Martin D Brand
Uncoupling protein 3 protects aconitase against inactivation in isolated skeletal muscle mitochondria.
Biochimica et biophysica acta 2005;1709(2):150-6.
2005: Telma C Esteves; Martin D Brand
The reactions catalysed by the mitochondrial uncoupling proteins UCP2 and UCP3.
Biochimica et biophysica acta 2005;1709(1):35-44.
2005: Martin D Brand; Telma C Esteves
Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3.
Cell metabolism 2005;2(2):85-93.
2005: Christopher J Lelliott; Miguel López; R Keira Curtis; Nadeene Parker; Matthias Laudes; Giles Yeo; Mercedes Jimenez-Liñan; Johannes Grosse; Asish K Saha; David Wiggins; David Hauton; Martin D Brand; Stephen O'Rahilly; Julian L Griffin; Geoffrey F Gibbons; Antonio Vidal-Puig
Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(9):1108-19.
2005: Karim S Echtay; Julian L Pakay; Telma C Esteves; Martin D Brand
Hydroxynonenal and uncoupling proteins: a model for protection against oxidative damage.
BioFactors (Oxford, England) 2005;24(1-4):119-30.
2004: Adrian J Lambert; Martin D Brand
Inhibitors of the quinone-binding site allow rapid superoxide production from mitochondrial NADH:ubiquinone oxidoreductase (complex I).
The Journal of biological chemistry 2004;279(38):39414-20.
2004: Martin D Brand; Charles Affourtit; Telma C Esteves; Katherine Green; Adrian J Lambert; Satomi Miwa; Julian L Pakay; Nadeene Parker
Mitochondrial superoxide: production, biological effects, and activation of uncoupling proteins.
Free radical biology & medicine 2004;37(6):755-67.
2004: Adrian J Lambert; Martin D Brand
Superoxide production by NADH:ubiquinone oxidoreductase (complex I) depends on the pH gradient across the mitochondrial inner membrane.
The Biochemical journal 2004;382(Pt 2):511-7.
2004: Darren A Talbot; Claude Duchamp; Benjamin Rey; Nicolas Hanuise; Jean-Louis Rouanet; Brigitte Sibille; Martin D Brand
Uncoupling protein and ATP/ADP carrier increase mitochondrial proton conductance after cold adaptation of king penguins.
The Journal of physiology 2004;558(Pt 1):123-35.
2004: Satomi Miwa; Kumars Riyahi; Linda Partridge; Martin D Brand
Lack of correlation between mitochondrial reactive oxygen species production and life span in Drosophila.
Annals of the New York Academy of Sciences 2004;1019():388-91.
2004: John R Speakman; Darren A Talbot; Colin Selman; Sam Snart; Jane S McLaren; Paula Redman; Ela Krol; Diane M Jackson; Maria S Johnson; Martin D Brand
Uncoupled and surviving: individual mice with high metabolism have greater mitochondrial uncoupling and live longer.
Aging cell 2004;3(3):87-95.
2004: R Keira Curtis; Martin D Brand
Analysing microarray data using modular regulation analysis.
Bioinformatics (Oxford, England) 2004;20(8):1272-84.
2004: Telma C Esteves; Karim S Echtay; Tanya Jonassen; Catherine F Clarke; Martin D Brand
Ubiquinone is not required for proton conductance by uncoupling protein 1 in yeast mitochondria.
The Biochemical journal 2004;379(Pt 2):309-15.
2004: Katherine Green; Martin D Brand; Michael P Murphy
Prevention of mitochondrial oxidative damage as a therapeutic strategy in diabetes.
Diabetes 2004;53 Suppl 1():S110-8.
2004: Darren A Talbot; Adrian J Lambert; Martin D Brand
Production of endogenous matrix superoxide from mitochondrial complex I leads to activation of uncoupling protein 3.
FEBS letters 2004;556(1-3):111-5.
2004: Martin D Brand; Julie A Buckingham; Telma C Esteves; Katherine Green; Adrian J Lambert; Satomi Miwa; Michael P Murphy; Julian L Pakay; Darren A Talbot; Karim S Echtay
Mitochondrial superoxide and aging: uncoupling-protein activity and superoxide production.
Biochemical Society symposium 2004;(71):203-13.
2003: Darren A Talbot; Nicolas Hanuise; Benjamin Rey; Jean-Louis Rouanet; Claude Duchamp; Martin D Brand
Superoxide activates a GDP-sensitive proton conductance in skeletal muscle mitochondria from king penguin (Aptenodytes patagonicus).
Biochemical and biophysical research communications 2003;312(4):983-8.
2003: Martin D Brand; Nigel Turner; Augustine Ocloo; Paul L Else; Anthony J Hulbert
Proton conductance and fatty acyl composition of liver mitochondria correlates with body mass in birds.
The Biochemical journal 2003;376(Pt 3):741-8.
2003: Michael P Murphy; Karim S Echtay; Frances H Blaikie; Jordi Asin-Cayuela; Helena M Cocheme; Katherine Green; Julie A Buckingham; Ellen R Taylor; Fiona Hurrell; Gillian Hughes; Satomi Miwa; Chris E Cooper; Dimitri A Svistunenko; Robin A J Smith; Martin D Brand
Superoxide activates uncoupling proteins by generating carbon-centered radicals and initiating lipid peroxidation: studies using a mitochondria-targeted spin trap derived from alpha-phenyl-N-tert-butylnitrone.
The Journal of biological chemistry 2003;278(49):48534-45.
2003: R Keira Curtis; Martin D Brand
Extracting meaning from microarray data.
Biochemical Society transactions 2003;31(Pt 6):1474-5.
2003: S Miwa; Martin D Brand
Mitochondrial matrix reactive oxygen species production is very sensitive to mild uncoupling.
Biochemical Society transactions 2003;31(Pt 6):1300-1.
2003: Mika B Jekabsons; Karim S Echtay; Ignacio Arechaga; Martin D Brand
Molecular properties of purified human uncoupling protein 2 refolded from bacterial inclusion bodies.
Journal of bioenergetics and biomembranes 2003;35(5):409-18.
2003: Karim S Echtay; Telma C Esteves; Julian L Pakay; Mika B Jekabsons; Adrian J Lambert; Manuel Portero-Otín; Reinald Pamplona; Antonio Vidal-Puig; Steven Wang; Stephen J Roebuck; Martin D Brand
A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling.
The EMBO journal 2003;22(16):4103-10.
2003: Aline Meirhaeghe; Vivion Crowley; Carol Lenaghan; Christopher J Lelliott; Kath Green; Abigail Stewart; Kevin Hart; Sven Schinner; Jaswinder Sethi; Giles Yeo; Martin D Brand; Ronald N Cortright; Stephen O'Rahilly; Montague Carl; Antonio Vidal-Puig
Characterization of the human, mouse and rat PGC1 beta (peroxisome-proliferator-activated receptor-gamma co-activator 1 beta) gene in vitro and in vivo.
The Biochemical journal 2003;373(Pt 1):155-65.
2003: Michael J Considine; Megan Goodman; Karim S Echtay; Maryse Laloi; James Whelan; Martin D Brand; Lee J Sweetlove
Superoxide stimulates a proton leak in potato mitochondria that is related to the activity of uncoupling protein.
The Journal of biological chemistry 2003;278(25):22298-302.
2002: Karim S Echtay; Michael P Murphy; Robin A J Smith; Darren A Talbot; Martin D Brand
Superoxide activates mitochondrial uncoupling protein 2 from the matrix side. Studies using targeted antioxidants.
The Journal of biological chemistry 2002;277(49):47129-35.
2002: Martin D Brand; Reinald Pamplona; Manuel Portero-Otín; Jesús R Requena; Stephen J Roebuck; Julie A Buckingham; John Clapham; Susana Cadenas
Oxidative damage and phospholipid fatty acyl composition in skeletal muscle mitochondria from mice underexpressing or overexpressing uncoupling protein 3.
The Biochemical journal 2002;368(Pt 2):597-603.
2002: Julie St-Pierre; Julie A Buckingham; Stephen J Roebuck; Martin D Brand
Topology of superoxide production from different sites in the mitochondrial electron transport chain.
The Journal of biological chemistry 2002;277(47):44784-90.
2002: Mika B Jekabsons; Karim S Echtay; Martin D Brand
Nucleotide binding to human uncoupling protein-2 refolded from bacterial inclusion bodies.
The Biochemical journal 2002;366(Pt 2):565-71.
2002: Damien Roussel; Marilyn Harding; Michael J Runswick; John E Walker; Martin D Brand
Does any yeast mitochondrial carrier have a native uncoupling protein function?
Journal of bioenergetics and biomembranes 2002;34(3):165-76.
2002: Martin D Brand; R Keira Curtis
Simplifying metabolic complexity.
Biochemical Society transactions 2002;30(2):25-30.
2002: T Bishop; Augustine Ocloo; Martin D Brand
Structure and function of mitochondria in hepatopancreas cells from metabolically depressed snails.
Physiological and biochemical zoology : PBZ 2002;75(2):134-44.
2002: Tammie Bishop; Julie St-Pierre; Martin D Brand
Primary causes of decreased mitochondrial oxygen consumption during metabolic depression in snail cells.
American journal of physiology. Regulatory, integrative and comparative physiology 2002;282(2):R372-82.
2002: Susana Cadenas; Karim S Echtay; James A Harper; Mika B Jekabsons; Julie A Buckingham; Evelyn Grau; Alejandro Abuin; Helen Chapman; John Clapham; Martin D Brand
The basal proton conductance of skeletal muscle mitochondria from transgenic mice overexpressing or lacking uncoupling protein-3.
The Journal of biological chemistry 2002;277(4):2773-8.
2002: Karim S Echtay; Damien Roussel; Julie St-Pierre; Mika B Jekabsons; Susana Cadenas; Jeff A Stuart; James A Harper; Stephen J Roebuck; Alastair Morrison; Susan Pickering; John Clapham; Martin D Brand
Superoxide activates mitochondrial uncoupling proteins.
Nature 2002;415(6867):96-9.
2002: R Keira Curtis; Martin D Brand
Control analysis of DNA microarray expression data.
Molecular biology reports 2002;29(1-2):67-71.
2002: James A Harper; Jeff A Stuart; Mika B Jekabsons; Damien Roussel; Kevin M Brindle; Keith Dickinson; Robert B Jones; Martin D Brand
Artifactual uncoupling by uncoupling protein 3 in yeast mitochondria at the concentrations found in mouse and rat skeletal-muscle mitochondria.
The Biochemical journal 2002;361(Pt 1):49-56.
2001: James A Harper; K Dickinson; Martin D Brand
Mitochondrial uncoupling as a target for drug development for the treatment of obesity.
Obesity reviews : an official journal of the International Association for the Study of Obesity 2001;2(4):255-65.
2001: Karim S Echtay; Martin D Brand
Coenzyme Q induces GDP-sensitive proton conductance in kidney mitochondria.
Biochemical Society transactions 2001;29(Pt 6):763-8.
2001: Jeff A Stuart; James A Harper; Kevin M Brindle; Mika B Jekabsons; Martin D Brand
A mitochondrial uncoupling artifact can be caused by expression of uncoupling protein 1 in yeast.
The Biochemical journal 2001;356(Pt 3):779-89.
2001: Jeff A Stuart; James A Harper; Kevin M Brindle; Mika B Jekabsons; Martin D Brand
Physiological levels of mammalian uncoupling protein 2 do not uncouple yeast mitochondria.
The Journal of biological chemistry 2001;276(21):18633-9.
2001: Jeff A Stuart; Susana Cadenas; Mika B Jekabsons; Damien Roussel; Martin D Brand
Mitochondrial proton leak and the uncoupling protein 1 homologues.
Biochimica et biophysica acta 2001;1504(1):144-58.
2000: S Krauss; Martin D Brand
Quantitation of signal transduction.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(15):2581-8.
2000: T Bishop; Martin D Brand
Processes contributing to metabolic depression in hepatopancreas cells from the snail Helix aspersa.
The Journal of experimental biology 2000;203(Pt 23):3603-12.
2000: Susana Cadenas; Julie A Buckingham; Julie St-Pierre; K Dickinson; R B Jones; Martin D Brand
AMP decreases the efficiency of skeletal-muscle mitochondria.
The Biochemical journal 2000;351 Pt 2():307-11.
2000: Martin D Brand
Uncoupling to survive? The role of mitochondrial inefficiency in ageing.
Experimental gerontology 2000;35(6-7):811-20.
2000: John Clapham; Jonathan R S Arch; Helen Chapman; A Haynes; Carolyn A Lister; Gary B T Moore; V Piercy; S A Carter; I Lehner; Stephen A Smith; LJ Beeley; R J Godden; N Herrity; M Skehel; Kumar Changani; Paul D Hockings; David G Reid; S M Squires; Jonathan P Hatcher; B Trail; JK Latcham; S Rastan; Alex J Harper; Susana Cadenas; J A Buckingham; Martin D Brand; Alejandro Abuin
Mice overexpressing human uncoupling protein-3 in skeletal muscle are hyperphagic and lean.
Nature 2000;406(6794):415-8.
2000: Julie St-Pierre; Martin D Brand; Robert G Boutilier
Mitochondria as ATP consumers: cellular treason in anoxia.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(15):8670-4.
2000: Susana Cadenas; Martin D Brand
Effects of magnesium and nucleotides on the proton conductance of rat skeletal-muscle mitochondria.
The Biochemical journal 2000;348 Pt 1():209-13.
2000: Michael Guppy; David C Reeves; T Bishop; Philip C Withers; J A Buckingham; Martin D Brand
Intrinsic metabolic depression in cells isolated from the hepatopancreas of estivating snails.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(7):999-1004.
2000: Julie St-Pierre; Martin D Brand; Robert G Boutilier
The effect of metabolic depression on proton leak rate in mitochondria from hibernating frogs.
The Journal of experimental biology 2000;203(Pt 9):1469-76.
2000: N I Kavanagh; EK Ainscow; Martin D Brand
Calcium regulation of oxidative phosphorylation in rat skeletal muscle mitochondria.
Biochimica et biophysica acta 2000;1457(1-2):57-70.
1999: Susana Cadenas; Julie A Buckingham; Sonia Samec; Josiane Seydoux; N Din; Abdul G Dulloo; Martin D Brand
UCP2 and UCP3 rise in starved rat skeletal muscle but mitochondrial proton conductance is unchanged.
FEBS letters 1999;462(3):257-60.
1999: EK Ainscow; Martin D Brand
Internal regulation of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes.
European journal of biochemistry / FEBS 1999;266(3):737-49.
1999: EK Ainscow; Martin D Brand
The responses of rat hepatocytes to glucagon and adrenaline. Application of quantified elasticity analysis.
European journal of biochemistry / FEBS 1999;265(3):1043-55.
1999: Jeff A Stuart; Kevin M Brindle; James A Harper; Martin D Brand
Mitochondrial proton leak and the uncoupling proteins.
Journal of bioenergetics and biomembranes 1999;31(5):517-25.
1999: Jeff A Stuart; James A Harper; Kevin M Brindle; Martin D Brand
Uncoupling protein 2 from carp and zebrafish, ectothermic vertebrates.
Biochimica et biophysica acta 1999;1413(1):50-4.
1999: EK Ainscow; Martin D Brand
Top-down control analysis of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes.
European journal of biochemistry / FEBS 1999;263(3):671-85.
1999: S Krauss; F Buttgereit; Martin D Brand
Effects of the mitogen concanavalin A on pathways of thymocyte energy metabolism.
Biochimica et biophysica acta 1999;1412(2):129-38.
1999: Martin D Brand; Kevin M Brindle; Julie A Buckingham; James A Harper; DF Rolfe; Jeff A Stuart
The significance and mechanism of mitochondrial proton conductance.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1999;23 Suppl 6():S4-11.
1999: DF Rolfe; John M B Newman; Julie A Buckingham; Michael G Clark; Martin D Brand
Contribution of mitochondrial proton leak to respiration rate in working skeletal muscle and liver and to SMR.
The American journal of physiology 1999;276(3 Pt 1):C692-9.
1999: EK Ainscow; Martin D Brand
Quantifying elasticity analysis: how external effectors cause changes to metabolic systems.
Bio Systems 1999;49(2):151-9.
1998: EK Ainscow; Martin D Brand
Errors associated with metabolic control analysis. Application Of Monte-Carlo simulation of experimental data.
Journal of theoretical biology 1998;194(2):223-33.
1998: EK Ainscow; Martin D Brand
Control analysis of systems with reaction blocks that 'cross-talk'.
Biochimica et biophysica acta 1998;1366(3):284-90.
1998: P S Brookes; J A Buckingham; A M Tenreiro; anthony hulbert; Martin D Brand
The proton permeability of the inner membrane of liver mitochondria from ectothermic and endothermic vertebrates and from obese rats: correlations with standard metabolic rate and phospholipid fatty acid composition.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 1998;119(2):325-34.
1997: P S Brookes; anthony hulbert; Martin D Brand
The proton permeability of liposomes made from mitochondrial inner membrane phospholipids: no effect of fatty acid composition.
Biochimica et biophysica acta 1997;1330(2):157-64.
1997: DF Rolfe; Martin D Brand
The physiological significance of mitochondrial proton leak in animal cells and tissues.
Bioscience reports 1997;17(1):9-16.
1997: P S Brookes; DF Rolfe; Martin D Brand
The proton permeability of liposomes made from mitochondrial inner membrane phospholipids: comparison with isolated mitochondria.
The Journal of membrane biology 1997;155(2):167-74.
1997: Martin D Brand
Regulation analysis of energy metabolism.
The Journal of experimental biology 1997;200(Pt 2):193-202.
1996: L F Chien; Martin D Brand
The effect of chloroform on mitochondrial energy transduction.
The Biochemical journal 1996;320 ( Pt 3)():837-45.
1996: R K Porter; Anthony J Hulbert; Martin D Brand
Allometry of mitochondrial proton leak: influence of membrane surface area and fatty acid composition.
The American journal of physiology 1996;271(6 Pt 2):R1550-60.
1996: Martin D Brand
Top down metabolic control analysis.
Journal of theoretical biology 1996;182(3):351-60.
1996: DF Rolfe; Martin D Brand
Contribution of mitochondrial proton leak to skeletal muscle respiration and to standard metabolic rate.
The American journal of physiology 1996;271(4 Pt 1):C1380-9.
1996: DF Rolfe; Martin D Brand
Proton leak and control of oxidative phosphorylation in perfused, resting rat skeletal muscle.
Biochimica et biophysica acta 1996;1276(1):45-50.
1995: F Buttgereit; Martin D Brand
A hierarchy of ATP-consuming processes in mammalian cells.
The Biochemical journal 1995;312 ( Pt 1)():163-7.
1995: R K Porter; Martin D Brand
Causes of differences in respiration rate of hepatocytes from mammals of different body mass.
The American journal of physiology 1995;269(5 Pt 2):R1213-24.
1995: R K Porter; Martin D Brand
Mitochondrial proton conductance and H+/O ratio are independent of electron transport rate in isolated hepatocytes.
The Biochemical journal 1995;310 ( Pt 2)():379-82.
1995: EK Ainscow; Martin D Brand
Top-down control analysis of systems with more than one common intermediate.
European journal of biochemistry / FEBS 1995;231(3):579-86.
1995: R K Porter; Martin D Brand
Cellular oxygen consumption depends on body mass.
The American journal of physiology 1995;269(1 Pt 2):R226-8.
1995: Martin D Brand; A Kesseler
Control analysis of energy metabolism in mitochondria.
Biochemical Society transactions 1995;23(2):371-6.
1994: DF Rolfe; Anthony J Hulbert; Martin D Brand
Characteristics of mitochondrial proton leak and control of oxidative phosphorylation in the major oxygen-consuming tissues of the rat.
Biochimica et biophysica acta 1994;1188(3):405-16.
1994: Martin D Brand; B P Vallis; A Kesseler
The sum of flux control coefficients in the electron-transport chain of mitochondria.
European journal of biochemistry / FEBS 1994;226(3):819-29.
1994: A Kesseler; Martin D Brand
Quantitative determination of the regulation of oxidative phosphorylation by cadmium in potato tuber mitochondria.
European journal of biochemistry / FEBS 1994;225(3):923-35.
1994: A Kesseler; Martin D Brand
Effects of cadmium on the control and internal regulation of oxidative phosphorylation in potato tuber mitochondria.
European journal of biochemistry / FEBS 1994;225(3):907-22.
1994: A Kesseler; Martin D Brand
Localisation of the sites of action of cadmium on oxidative phosphorylation in potato tuber mitochondria using top-down elasticity analysis.
European journal of biochemistry / FEBS 1994;225(3):897-906.
1994: Martin D Brand; L F Chien; EK Ainscow; DF Rolfe; R K Porter
The causes and functions of mitochondrial proton leak.
Biochimica et biophysica acta 1994;1187(2):132-9.
1994: M E Harper; Martin D Brand
Hyperthyroidism stimulates mitochondrial proton leak and ATP turnover in rat hepatocytes but does not change the overall kinetics of substrate oxidation reactions.
Canadian journal of physiology and pharmacology 1994;72(8):899-908.
1994: Martin D Brand; P Couture; Anthony J Hulbert
Liposomes from mammalian liver mitochondria are more polyunsaturated and leakier to protons than those from reptiles.
Comparative biochemistry and physiology. Biochemistry and molecular biology 1994;108(2):181-8.
1994: Martin D Brand; L F Chien; P Diolez
Experimental discrimination between proton leak and redox slip during mitochondrial electron transport.
The Biochemical journal 1994;297 ( Pt 1)():27-9.
1993: M E Harper; J S Ballantyne; M Leach; Martin D Brand
Effects of thyroid hormones on oxidative phosphorylation.
Biochemical Society transactions 1993;21 ( Pt 3)(3):785-92.
1993: Martin D Brand; L F Chien; DF Rolfe
Control of oxidative phosphorylation in liver mitochondria and hepatocytes.
Biochemical Society transactions 1993;21 ( Pt 3)(3):757-62.
1993: M E Harper; Martin D Brand
The quantitative contributions of mitochondrial proton leak and ATP turnover reactions to the changed respiration rates of hepatocytes from rats of different thyroid status.
The Journal of biological chemistry 1993;268(20):14850-60.
1993: Martin D Brand; M E Harper; H C Taylor
Control of the effective P/O ratio of oxidative phosphorylation in liver mitochondria and hepatocytes.
The Biochemical journal 1993;291 ( Pt 3)():739-48.
1993: C P Kaplan; R K Porter; Martin D Brand
The choline transporter is the major site of control of choline oxidation in isolated rat liver mitochondria.
FEBS letters 1993;321(1):24-6.
1993: R K Porter; Martin D Brand
Body mass dependence of H+ leak in mitochondria and its relevance to metabolic rate.
Nature 1993;362(6421):628-30.
1992: R K Porter; J M Scott; Martin D Brand
Choline transport into rat liver mitochondria.
Biochemical Society transactions 1992;20(3):248S.
1992: R K Porter; J M Scott; Martin D Brand
The nature of betaine efflux from rat liver mitochondria.
Biochemical Society transactions 1992;20(3):247S.
1992: Martin D Brand; D Steverding; B Kadenbach; P M Stevenson; R P Hafner
The mechanism of the increase in mitochondrial proton permeability induced by thyroid hormones.
European journal of biochemistry / FEBS 1992;206(3):775-81.
1991: Guy C Brown; Martin D Brand
On the nature of the mitochondrial proton leak.
Biochimica et biophysica acta 1991;1059(1):55-62.
1991: Martin D Brand; P Couture; Paul L Else; K W Withers; Anthony J Hulbert
Evolution of energy metabolism. Proton permeability of the inner membrane of liver mitochondria is greater in a mammal than in a reptile.
The Biochemical journal 1991;275 ( Pt 1)():81-6.
1991: R P Hafner; Martin D Brand
Effect of protonmotive force on the relative proton stoichiometries of the mitochondrial proton pumps.
The Biochemical journal 1991;275 ( Pt 1)():75-80.
1990: Martin D Brand; L D'Alessandri; Helena REIS; R P Hafner
Stimulation of the electron transport chain in mitochondria isolated from rats treated with mannoheptulose or glucagon.
Archives of biochemistry and biophysics 1990;283(2):278-84.
1990: Guy C Brown; Patricia L Lakin-Thomas; Martin D Brand
Control of respiration and oxidative phosphorylation in isolated rat liver cells.
European journal of biochemistry / FEBS 1990;192(2):355-62.
1990: C D Nobes; W W Hay; Martin D Brand
The mechanism of stimulation of respiration by fatty acids in isolated hepatocytes.
The Journal of biological chemistry 1990;265(22):12910-5.
1990: C D Nobes; Guy C Brown; P N Olive; Martin D Brand
Non-ohmic proton conductance of the mitochondrial inner membrane in hepatocytes.
The Journal of biological chemistry 1990;265(22):12903-9.
1990: Martin D Brand
The proton leak across the mitochondrial inner membrane.
Biochimica et biophysica acta 1990;1018(2-3):128-33.
1990: Martin D Brand
The contribution of the leak of protons across the mitochondrial inner membrane to standard metabolic rate.
Journal of theoretical biology 1990;145(2):267-86.
1990: Guy C Brown; R P Hafner; Martin D Brand
A 'top-down' approach to the determination of control coefficients in metabolic control theory.
European journal of biochemistry / FEBS 1990;188(2):321-5.
1990: R P Hafner; Guy C Brown; Martin D Brand
Analysis of the control of respiration rate, phosphorylation rate, proton leak rate and protonmotive force in isolated mitochondria using the 'top-down' approach of metabolic control theory.
European journal of biochemistry / FEBS 1990;188(2):313-9.
1990: R P Hafner; Guy C Brown; Martin D Brand
Thyroid-hormone control of state-3 respiration in isolated rat liver mitochondria.
The Biochemical journal 1990;265(3):731-4.
1990: J D Johnston; Martin D Brand
The mechanism of Ca2+ stimulation of citrulline and N-acetylglutamate synthesis by mitochondria.
Biochimica et biophysica acta 1990;1033(1):85-90.
1990: PA Quant; P K Tubbs; Martin D Brand
Glucagon activates mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase in vivo by decreasing the extent of succinylation of the enzyme.
European journal of biochemistry / FEBS 1990;187(1):169-74.
1989: C D Nobes; Martin D Brand
A quantitative assessment of the use of 36Cl- distribution to measure plasma membrane potential in isolated hepatocytes.
Biochimica et biophysica acta 1989;987(1):115-23.
1989: C D Nobes; Patricia L Lakin-Thomas; Martin D Brand
The contribution of ATP turnover by the Na+/K+-ATPase to the rate of respiration of hepatocytes. Effects of thyroid status and fatty acids.
Biochimica et biophysica acta 1989;976(2-3):241-5.
1989: PA Quant; P K Tubbs; Martin D Brand
Treatment of rats with glucagon or mannoheptulose increases mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase activity and decreases succinyl-CoA content in liver.
The Biochemical journal 1989;262(1):159-64.
1989: R P Hafner; M J Leake; Martin D Brand
Hypothyroidism in rats decreases mitochondrial inner membrane cation permeability.
FEBS letters 1989;248(1-2):175-8.
1989: J D Johnston; Martin D Brand
Sub-micromolar concentrations of extramitochondrial Ca2+ stimulate the rate of citrulline synthesis by rat liver mitochondria.
The Biochemical journal 1989;257(1):285-8.
1988: R P Hafner; C D Nobes; A D McGown; Martin D Brand
Altered relationship between protonmotive force and respiration rate in non-phosphorylating liver mitochondria isolated from rats of different thyroid hormone status.
European journal of biochemistry / FEBS 1988;178(2):511-8.
1988: Patricia L Lakin-Thomas; Martin D Brand
Stimulation of respiration by mitogens in rat thymocytes is independent of mitochondrial calcium.
The Biochemical journal 1988;256(1):167-73.
1988: Martin D Brand; R P Hafner; Guy C Brown
Control of respiration in non-phosphorylating mitochondria is shared between the proton leak and the respiratory chain.
The Biochemical journal 1988;255(2):535-9.
1988: Guy C Brown; Martin D Brand
Proton/electron stoichiometry of mitochondrial complex I estimated from the equilibrium thermodynamic force ratio.
The Biochemical journal 1988;252(2):473-9.
1988: M P Murphy; Martin D Brand
The stoichiometry of charge translocation by cytochrome oxidase and the cytochrome bc1 complex of mitochondria at high membrane potential.
European journal of biochemistry / FEBS 1988;173(3):645-51.
1988: M P Murphy; Martin D Brand
Membrane-potential-dependent changes in the stoichiometry of charge translocation by the mitochondrial electron transport chain.
European journal of biochemistry / FEBS 1988;173(3):637-44.
1988: R P Hafner; Martin D Brand
Hypothyroidism in rats does not lower mitochondrial ADP/O and H+/O ratios.
The Biochemical journal 1988;250(2):477-84.
1987: Patricia L Lakin-Thomas; Martin D Brand
Mitogenic stimulation transiently increases the exchangeable mitochondrial calcium pool in rat thymocytes.
The Biochemical journal 1987;246(1):173-7.
1987: J D Johnston; Martin D Brand
Stimulation of the respiration rate of rat liver mitochondria by sub-micromolar concentrations of extramitochondrial Ca2+.
The Biochemical journal 1987;245(1):217-22.