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Jeannette Watson

Research Profile

Chemicals & Drugs

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TOP 3
Christopher J Langmead; Jeannette Watson; Charlie Reavill
Muscarinic acetylcholine receptors as CNS drug targets.
Claire Scott; Christopher J Langmead; Kirsten L Clarke; Paul A Wyman; Paul W Smith; Kathryn R Starr; Lee A Dawson; Gary W Price; James Hagan; Jeannette Watson
SB-616234-A (1-[6-(cis-3,5-dimethylpiperazin-1-yl)-2,3-dihydro-5-methoxyindol-1-yl]-1-[2'methyl-4'-(5-methyl-1,2,3-oxadiazol-3-yl)biphenyl-4-yl]methanone hydrochloride): a novel, potent and selective 5-HT1B receptor antagonist.
Claire Scott; Ellen M Soffin; Matthew Hill; Peter J Atkinson; Christopher J Langmead; Paul B Wren; Stefania Faedo; Laurie J Gordon; Gary W Price; Steven M Bromidge; Christopher N Johnson; James Hagan; Jeannette Watson
SB-649915, a novel, potent 5-HT1A and 5-HT1B autoreceptor antagonist and 5-HT re-uptake inhibitor in native tissue.

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All Publications

2008: Christopher J Langmead; Jeannette Watson; Charlie Reavill
Muscarinic acetylcholine receptors as CNS drug targets.
Pharmacology & therapeutics 2008;117(2):232-43.
2006: Claire Scott; Christopher J Langmead; Kirsten L Clarke; Paul A Wyman; Paul W Smith; Kathryn R Starr; Lee A Dawson; Gary W Price; James Hagan; Jeannette Watson
SB-616234-A (1-[6-(cis-3,5-dimethylpiperazin-1-yl)-2,3-dihydro-5-methoxyindol-1-yl]-1-[2'methyl-4'-(5-methyl-1,2,3-oxadiazol-3-yl)biphenyl-4-yl]methanone hydrochloride): a novel, potent and selective 5-HT1B receptor antagonist.
Neuropharmacology 2006;50(8):984-90.
2006: Claire Scott; Ellen M Soffin; Matthew Hill; Peter J Atkinson; Christopher J Langmead; Paul B Wren; Stefania Faedo; Laurie J Gordon; Gary W Price; Steven M Bromidge; Christopher N Johnson; James Hagan; Jeannette Watson
SB-649915, a novel, potent 5-HT1A and 5-HT1B autoreceptor antagonist and 5-HT re-uptake inhibitor in native tissue.
European journal of pharmacology 2006;536(1-2):54-61.
2001: Jeannette Watson; Claire Roberts; Claire Scott; I Kendall; LJ Collin; N C Day; Mark H Harries; Ellen M Soffin; Ceri H Davies; Andrew D Randall; T Heightman; Laramie M Gaster; Paul A Wyman; C Parker; Gary W Price; Derek N Middlemiss
SB-272183, a selective 5-HT(1A), 5-HT(1B) and 5-HT(1D) receptor antagonist in native tissue.
British journal of pharmacology 2001;133(6):797-806.
2000: Jeannette Watson; LJ Collin; M Ho; Graham Riley; Claire Scott; Julie V Selkirk; Gary W Price
5-HT(1A) receptor agonist-antagonist binding affinity difference as a measure of intrinsic activity in recombinant and native tissue systems.
British journal of pharmacology 2000;130(5):1108-14.
1999: Derek N Middlemiss; Manfred Göthert; Eberhard Schlicker; Claire M Scott; Julie V Selkirk; Jeannette Watson; Laramie M Gaster; Paul A Wyman; Graham Riley; Gary W Price
SB-236057, a selective 5-HT1B receptor inverse agonist, blocks the 5-HT human terminal autoreceptor.
European journal of pharmacology 1999;375(1-3):359-65.
1998: Julie V Selkirk; Claire Scott; M Ho; M J Burton; Jeannette Watson; Laramie M Gaster; LJ Collin; BJ Jones; Derek N Middlemiss; Gary W Price
SB-224289--a novel selective (human) 5-HT1B receptor antagonist with negative intrinsic activity.
British journal of pharmacology 1998;125(1):202-8.
1996: Claire Roberts; Jeannette Watson; M Burton; Gary W Price; BJ Jones
Functional characterization of the 5-HT terminal autoreceptor in the guinea-pig brain cortex.
British journal of pharmacology 1996;117(2):384-8.