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Dianne Watters

Research Profile

Disorders

Ataxia Telangiectasia

Chemicals & Drugs

Anatomy

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Publications

TOP 3
Philip Chen; Cheng Peng; John Luff; Kevin Spring; Dianne Watters; Steven E Bottle; Shigeki Furuya; Martin F Lavin
Oxidative stress is responsible for deficient survival and dendritogenesis in purkinje neurons from ataxia-telangiectasia mutated mutant mice.
Katherine Keating; Nuri Gueven; Dianne Watters; H Peter Rodemann; Martin F Lavin
Transcriptional downregulation of ATM by EGF is defective in ataxia-telangiectasia cells expressing mutant protein.
Kevin Spring; S Cross; C Li; Dianne Watters; L Ben-Senior; P Waring; F Ahangari; S L Lu; Philip Chen; Ihor Misko; C Paterson; G Kay; Nechama I Smorodinsky; Yosef Shiloh; Martin F Lavin
Atm knock-in mice harboring an in-frame deletion corresponding to the human ATM 7636del9 common mutation exhibit a variant phenotype.

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All Publications

2003: Philip Chen; Cheng Peng; John Luff; Kevin Spring; Dianne Watters; Steven E Bottle; Shigeki Furuya; Martin F Lavin
Oxidative stress is responsible for deficient survival and dendritogenesis in purkinje neurons from ataxia-telangiectasia mutated mutant mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(36):11453-60.
2001: Katherine Keating; Nuri Gueven; Dianne Watters; H Peter Rodemann; Martin F Lavin
Transcriptional downregulation of ATM by EGF is defective in ataxia-telangiectasia cells expressing mutant protein.
Oncogene 2001;20(32):4281-90.
2001: Kevin Spring; S Cross; C Li; Dianne Watters; L Ben-Senior; P Waring; F Ahangari; S L Lu; Philip Chen; Ihor Misko; C Paterson; G Kay; Nechama I Smorodinsky; Yosef Shiloh; Martin F Lavin
Atm knock-in mice harboring an in-frame deletion corresponding to the human ATM 7636del9 common mutation exhibit a variant phenotype.
Cancer research 2001;61(11):4561-8.
2001: Nuri Gueven; Katherine Keating; P Chen; Toshiyuki Fukao; Kum Kum Khanna; Dianne Watters; P H Rodemann; Martin F Lavin
Epidermal growth factor sensitizes cells to ionizing radiation by down-regulating protein mutated in ataxia-telangiectasia.
The Journal of biological chemistry 2001;276(12):8884-91.
2000: Toshiyuki Fukao; T Yoshida; Hideo Kaneko; XQ Song; H Tashita; Takahide Teramoto; Ryosuke Inoue; Dianne Watters; Martin Lavin; Naomi Kondo
Immunoblot analysis for laboratory diagnosis of ataxia-telangiectasia: use of Epstein-Barr virus-transformed or phytohemagglutinin-stimulated lymphoblasts for detection of ATM protein.
Journal of investigational allergology & clinical immunology : official organ of the International Association of Asthmology (INTERASMA) and Sociedad Latinoamericana de Alergia e Inmunología 2000;10(1):36-40.
1999: Dianne Watters; Padmini Kedar; Kevin Spring; Jonas Bjorkman; Philip Chen; Magtouf Gatei; Geoff W Birrell; B Garrone; P Srinivasa; Denis I Crane; Martin F Lavin
Localization of a portion of extranuclear ATM to peroxisomes.
The Journal of biological chemistry 1999;274(48):34277-82.
1999: Toshiyuki Fukao; Hideo Kaneko; Geoff W Birrell; Magtouf Gatei; H Tashita; T Yoshida; S Cross; Padmini Kedar; Dianne Watters; K K Khana; Ihor Misko; Naomi Kondo; Martin F Lavin
ATM is upregulated during the mitogenic response in peripheral blood mononuclear cells.
Blood 1999;94(6):1998-2006.
1999: Dianne Watters; Peter G Parsons
Critical targets of protein kinase C in differentiation of tumour cells.
Biochemical pharmacology 1999;58(3):383-8.
1999: Dianne Watters
Molecular mechanisms of ionizing radiation-induced apoptosis.
Immunology and cell biology 1999;77(3):263-71.
1998: Nigel Waterhouse; DM Finucane; Douglas R Green; J S Elce; S Kumar; E S Alnemri; G Litwack; Kum Kum Khanna; Martin F Lavin; Dianne Watters
Calpain activation is upstream of caspases in radiation-induced apoptosis.
Cell death and differentiation 1998;5(12):1051-61.
1998: J Munns; John Yaxley; J Coomer; Martin F Lavin; Robert A Gardiner; Dianne Watters
Evaluation of the potential of transferrin-adriamycin conjugates in the treatment of bladder cancer.
British journal of urology 1998;82(2):284-9.
1998: KF Harvey; NL Harvey; J M Michael; G Parasivam; N Waterhouse; E S Alnemri; Dianne Watters; Sharad Kumar
Caspase-mediated cleavage of the ubiquitin-protein ligase Nedd4 during apoptosis.
The Journal of biological chemistry 1998;273(22):13524-30.
1998: Dianne Watters; B Garrone; J Coomer; W E Johnson; G Brown; P Parsons
Stimulation of melanogenesis in a human melanoma cell line by bistratene A.
Biochemical pharmacology 1998;55(10):1691-9.
1998: Shaun P Scott; N Zhang; Kum Kum Khanna; A Khromykh; Karen Hobson; Dianne Watters; Martin F Lavin
Cloning and expression of the ataxia-telangiectasia gene in baculovirus.
Biochemical and biophysical research communications 1998;245(1):144-8.
1998: Dianne Watters; N Waterhouse
Proteolytic targets in cell death.
Results and problems in cell differentiation 1998;24():25-44.
1997: B Garrone; Padmini Kedar; I Elarova; Martin Lavin; Dianne Watters
Approaches to determine the specific role of the delta isoform of protein kinase C.
Journal of biochemical and biophysical methods 1997;36(1):51-61.
1997: J M Michael; Martin F Lavin; Dianne Watters
Resistance to radiation-induced apoptosis in Burkitt's lymphoma cells is associated with defective ceramide signaling.
Cancer research 1997;57(16):3600-5.
1997: N Zhang; Philip Chen; Kum Kum Khanna; Shaun Scott; Magtouf Gatei; Sergei Kozlov; Dianne Watters; Kevin Spring; T Yen; Martin F Lavin
Isolation of full-length ATM cDNA and correction of the ataxia-telangiectasia cellular phenotype.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(15):8021-6.
1997: T Shafman; Kum Kum Khanna; Padmini Kedar; Kevin Spring; Sergei Kozlov; T Yen; Karen Hobson; Magtouf Gatei; N Zhang; Dianne Watters; M Egerton; Yosef Shiloh; S Kharbanda; Donald Kufe; Martin F Lavin
Interaction between ATM protein and c-Abl in response to DNA damage.
Nature 1997;387(6632):520-3.
1997: Dianne Watters; Kum Kum Khanna; Heather Beamish; Geoff W Birrell; Kevin Spring; Padmini Kedar; Magtouf Gatei; D Stenzel; Karen Hobson; Sergei Kozlov; N Zhang; A Farrell; Jonathan Ramsay; R Gatti; Martin Lavin
Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms.
Oncogene 1997;14(16):1911-21.
1997: Kum Kum Khanna; J Yan; Dianne Watters; Karen Hobson; Heather Beamish; Kevin Spring; Yosef Shiloh; Richard A Gatti; Martin F Lavin
Defective signaling through the B cell antigen receptor in Epstein-Barr virus-transformed ataxia-telangiectasia cells.
The Journal of biological chemistry 1997;272(14):9489-95.
1997: Q Song; T Wei; Susan Lees-Miller; E Alnemri; Dianne Watters; Martin F Lavin
Resistance of actin to cleavage during apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(1):157-62.
1996: Dianne Watters; B Garrone; G Gobert; S Williams; R Gardiner; Martin Lavin
Bistratene A causes phosphorylation of talin and redistribution of actin microfilaments in fibroblasts: possible role for PKC-delta.
Experimental cell research 1996;229(2):327-35.
1996: Nigel Waterhouse; Sharad Kumar; Q Song; P Strike; L Sparrow; G Dreyfuss; Emad S Alnemri; G Litwack; Martin Lavin; Dianne Watters
Heteronuclear ribonucleoproteins C1 and C2, components of the spliceosome, are specific targets of interleukin 1beta-converting enzyme-like proteases in apoptosis.
The Journal of biological chemistry 1996;271(46):29335-41.
1996: Martin F Lavin; Dianne Watters; Q Song
Role of protein kinase activity in apoptosis.
Experientia 1996;52(10-11):979-94.
1996: H Beamish; Richard Williams; Philip Chen; Kum Kum Khanna; Karen Hobson; Dianne Watters; Yosef Shiloh; Martin Lavin
Rapamycin resistance in ataxia-telangiectasia.
Oncogene 1996;13(5):963-70.
1996: G Griffiths; B Garrone; E Deacon; P Owen; Judit Pongracz; G Mead; A Bradwell; Dianne Watters; J Lord
The polyether bistratene A activates protein kinase C-delta and induces growth arrest in HL60 cells.
Biochemical and biophysical research communications 1996;222(3):802-8.
1996: Nancy E Liyou; S Hamilton; Dianne Watters; Ross Tellam; Peter Willadsen
Endocytosis by digest cells of the cattle tick Boophilus microplus: regulation by protein kinase C.
Insect biochemistry and molecular biology 1996;26(2):147-54.
1995: Martin F Lavin; Kum Kum Khanna; H Beamish; Kevin Spring; Dianne Watters; Yosef Shiloh
Relationship of the ataxia-telangiectasia protein ATM to phosphoinositide 3-kinase.
Trends in biochemical sciences 1995;20(10):382-3.
1994: Martin F Lavin; Kum Kum Khanna; H Beamish; B Teale; Karen Hobson; Dianne Watters
Defect in radiation signal transduction in ataxia-telangiectasia.
International journal of radiation biology 1994;66(6 Suppl):S151-6.
1994: Dianne Watters; H J Beamish; K A Marshall; R A Gardiner; G J Seymour; Martin F Lavin
Accumulation of HL-60 leukemia cells in G2/M and inhibition of cytokinesis caused by two marine compounds, bistratene A and cycloxazoline.
Cancer chemotherapy and pharmacology 1994;33(5):399-409.
1993: Dianne Watters; A L Van Den Brenk
Toxins from ascidians.
Toxicon : official journal of the International Society on Toxinology 1993;31(11):1349-72.
1993: Dianne Watters; I Ross; M McEwan; M Lavin
Purification and properties of a catechol oxidase from blood cells of the ascidian Pyura stolonifera.
Molecular marine biology and biotechnology 1993;2(1):28-40.
1992: Dianne Watters; J Michael; J E Hemphill; S E Hamilton; Martin F Lavin; George R Pettit
Bistratene A: a novel compound causing changes in protein phosphorylation patterns in human leukemia cells.
Journal of cellular biochemistry 1992;49(4):417-24.
1990: C J Hawkins; Martin F Lavin; K A Marshall; A L van den Brenk; Dianne Watters
Structure-activity relationships of the lissoclinamides: cytotoxic cyclic peptides from the ascidian Lissoclinum patella.
Journal of medicinal chemistry 1990;33(6):1634-8.
1990: Dianne Watters; K Marshall; S Hamilton; J Michael; M McArthur; G Seymour; C Hawkins; R Gardiner; Martin Lavin
The bistratenes: new cytotoxic marine macrolides which induce some properties indicative of differentiation in HL-60 cells.
Biochemical pharmacology 1990;39(10):1609-14.
1989: Bernard M Degnan; C J Hawkins; Martin F Lavin; E J McCaffrey; D L Parry; Dianne Watters
Novel cytotoxic compounds from the ascidian Lissoclinum bistratum.
Journal of medicinal chemistry 1989;32(6):1354-9.
1989: Bernard M Degnan; C J Hawkins; Martin F Lavin; E J McCaffrey; D L Parry; A L van den Brenk; Dianne Watters
New cyclic peptides with cytotoxic activity from the ascidian Lissoclinum patella.
Journal of medicinal chemistry 1989;32(6):1349-54.