Username

Password

Forgot Password?

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

Timothy Weaver

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Living Beings

Anatomy

Physiology

Post-Translational Protein Processing

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequence

Sign-in to see full Profile

Network (preview)

Co-Publications
Name
30
Whitsett, Jeffrey
14
Ikegami, Machiko
12
Na, Cheng-Lun
10
Akinbi, Henry
8
Clark, Jean
8
Hull, William
5
Conkright, Juliana
5
Bridges, James
5
Johansson, Jan
5
Wert, Susan
4
Stahlman, Mildred
4
Jobe, Alan
4
Nogee, Lawrence
4
Beck, DC
4
Glasser, Stephan

Sign-in to see all Coauthors

Publications

TOP 3
Ikegami Machiko; Weaver Timothy E; Grant Shawn N; Whitsett Jeffrey A
Pulmonary surfactant surface tension influences alveolar capillary shape and oxygenation.
Dong Mei; Bridges James P; Apsley Karen; Xu Yan; Weaver Timothy E
ERdj4 and ERdj5 are required for endoplasmic reticulum-associated protein degradation of misfolded surfactant protein C.
Ueno Takayuki; Elmberger Göran; Weaver Timothy E; Toi Masakazu; Linder Stig
The aspartic protease napsin A suppresses tumor growth independent of its catalytic activity.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Timothy Weaver (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Ikegami Machiko; Weaver Timothy E; Grant Shawn N; Whitsett Jeffrey A
Pulmonary surfactant surface tension influences alveolar capillary shape and oxygenation.
American journal of respiratory cell and molecular biology 2009;41(4):433-9.
2008: Dong Mei; Bridges James P; Apsley Karen; Xu Yan; Weaver Timothy E
ERdj4 and ERdj5 are required for endoplasmic reticulum-associated protein degradation of misfolded surfactant protein C.
Molecular biology of the cell 2008;19(6):2620-30.
2008: Ueno Takayuki; Elmberger Göran; Weaver Timothy E; Toi Masakazu; Linder Stig
The aspartic protease napsin A suppresses tumor growth independent of its catalytic activity.
Laboratory investigation; a journal of technical methods and pathology 2008;88(3):256-63.
2007: Stahlman Mildred T; Besnard Valérie; Wert Susan E; Weaver Timothy E; Dingle Sharon; Xu Yan; von Zychlin Kara; Olson Sandra J; Whitsett Jeffrey A
Expression of ABCA3 in developing lung and other tissues.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2007;55(1):71-83.
2006: Nash James A; Ballard Tiffany Nicole S; Weaver Timothy E; Akinbi Henry T
The peptidoglycan-degrading property of lysozyme is not required for bactericidal activity in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(1):519-26.
2006: Bridges James P; Xu Yan; Na Cheng-Lun; Wong Hector R; Weaver Timothy E
Adaptation and increased susceptibility to infection associated with constitutive expression of misfolded SP-C.
The Journal of cell biology 2006;172(3):395-407.
2006: Ryan Marnie A; Akinbi Henry T; Serrano Alicia G; Perez-Gil Jesus; Wu Huixing; McCormack Francis X; Weaver Timothy E
Antimicrobial activity of native and synthetic surfactant protein B peptides.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(1):416-25.
2006: Serrano Alicia G; Ryan Marnie; Weaver Timothy E; Pérez-Gil Jesús
Critical structure-function determinants within the N-terminal region of pulmonary surfactant protein SP-B.
Biophysical journal 2006;90(1):238-49.
2006: Bridges James P; Weaver Timothy E
Use of transgenic mice to study lung morphogenesis and function.
ILAR journal / National Research Council, Institute of Laboratory Animal Resources 2006;47(1):22-31.
2005: Ikegami Machiko; Whitsett Jeffrey A; Martis Prithy C; Weaver Timothy E
Reversibility of lung inflammation caused by SP-B deficiency.
American journal of physiology. Lung cellular and molecular physiology 2005;289(6):L962-70.
2005: Nesslein Lori L; Melton Kristin R; Ikegami Machiko; Na Cheng-Lun; Wert Susan E; Rice Ward R; Whitsett Jeffrey A; Weaver Timothy E
Partial SP-B deficiency perturbs lung function and causes air space abnormalities.
American journal of physiology. Lung cellular and molecular physiology 2005;288(6):L1154-61.
2005: Ryan Marnie A; Qi Xiaoyang; Serrano Alicia G; Ikegami Machiko; Perez-Gil Jesus; Johansson Jan; Weaver Timothy E
Mapping and analysis of the lytic and fusogenic domains of surfactant protein B.
Biochemistry 2005;44(3):861-72.
2004: Markart Philipp; Faust Nicole; Graf Thomas; Na Cheng-Lun; Weaver Timothy E; Akinbi Henry T
Comparison of the microbicidal and muramidase activities of mouse lysozyme M and P.
The Biochemical journal 2004;380(Pt 2):385-92.
2004: Li Jing; Hosia Waltteri; Hamvas Aaron; Thyberg Johan; Jörnvall Hans; Weaver Timothy E; Johansson Jan
The N-terminal propeptide of lung surfactant protein C is necessary for biosynthesis and prevents unfolding of a metastable alpha-helix.
Journal of molecular biology 2004;338(5):857-62.
2004: Li Jing; Ikegami Machiko; Na Cheng-Lun; Hamvas Aaron; Espinassous Quentin; Chaby Richard; Nogee Lawrence M; Weaver Timothy E; Johansson Jan
N-terminally extended surfactant protein (SP) C isolated from SP-B-deficient children has reduced surface activity and inhibited lipopolysaccharide binding.
Biochemistry 2004;43(13):3891-8.
2004: Ueno Takayuki; Linder Stig; Na Cheng-Lun; Rice Ward R; Johansson Jan; Weaver Timothy E
Processing of pulmonary surfactant protein B by napsin and cathepsin H.
The Journal of biological chemistry 2004;279(16):16178-84.
2004: Markart Philipp; Korfhagen Thomas R; Weaver Timothy E; Akinbi Henry T
Mouse lysozyme M is important in pulmonary host defense against Klebsiella pneumoniae infection.
American journal of respiratory and critical care medicine 2004;169(4):454-8.
2003: Bridges James P; Wert Susan E; Nogee Lawrence M; Weaver Timothy E
Expression of a human surfactant protein C mutation associated with interstitial lung disease disrupts lung development in transgenic mice.
The Journal of biological chemistry 2003;278(52):52739-46.
2003: Melton Kristin R; Nesslein Lori L; Ikegami Machiko; Tichelaar Jay W; Clark Jean C; Whitsett Jeffrey A; Weaver Timothy E
SP-B deficiency causes respiratory failure in adult mice.
American journal of physiology. Lung cellular and molecular physiology 2003;285(3):L543-9.
2003: Epaud Ralph; Ikegami Machiko; Whitsett Jeffrey A; Jobe Alan H; Weaver Timothy E; Akinbi Henry T
Surfactant protein B inhibits endotoxin-induced lung inflammation.
American journal of respiratory cell and molecular biology 2003;28(3):373-8.
2002: Weaver Timothy E; Na Cheng-Lun; Stahlman Mildred
Biogenesis of lamellar bodies, lysosome-related organelles involved in storage and secretion of pulmonary surfactant.
Seminars in cell & developmental biology 2002;13(4):263-70.
2002: Ikegami Machiko; Takabatake Noriaki; Weaver Timothy E
Intersubunit disulfide bridge is not required for the protective role of SP-B against lung inflammation.
Journal of applied physiology (Bethesda, Md. : 1985) 2002;93(2):505-11.
2002: Rice Ward R; Conkright Juliana J; Na Cheng-Lun; Ikegami Machiko; Shannon John M; Weaver Timothy E
Maintenance of the mouse type II cell phenotype in vitro.
American journal of physiology. Lung cellular and molecular physiology 2002;283(2):L256-64.
2002: Ikegami Machiko; Weaver Timothy E; Conkright Juliana J; Sly Peter D; Ross Gary F; Whitsett Jeffrey A; Glasser Stephan W
Deficiency of SP-B reveals protective role of SP-C during oxygen lung injury.
Journal of applied physiology (Bethesda, Md. : 1985) 2002;92(2):519-26.
2002: Conkright Juliana Johnson; Na Cheng-Lun; Weaver Timothy E
Overexpression of surfactant protein-C mature peptide causes neonatal lethality in transgenic mice.
American journal of respiratory cell and molecular biology 2002;26(1):85-90.
2001: Zaltash S; Griffiths W J; Beck D; Duan C X; Weaver T E; Johansson J
Membrane activity of (Cys48Ser) lung surfactant protein B increases with dimerisation.
Biological chemistry 2001;382(6):933-9.
2001: Conkright J J; Bridges J P; Na C L; Voorhout W F; Trapnell B; Glasser S W; Weaver T E
Secretion of surfactant protein C, an integral membrane protein, requires the N-terminal propeptide.
The Journal of biological chemistry 2001;276(18):14658-64.
2001: Mishra A; Weaver T E; Beck D C; Rothenberg M E
Interleukin-5-mediated allergic airway inflammation inhibits the human surfactant protein C promoter in transgenic mice.
The Journal of biological chemistry 2001;276(11):8453-9.
2001: Weaver T E; Conkright J J
Function of surfactant proteins B and C.
Annual review of physiology 2001;63():555-78.
2000: Akinbi H T; Epaud R; Bhatt H; Weaver T E
Bacterial killing is enhanced by expression of lysozyme in the lungs of transgenic mice.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(10):5760-6.
2000: Stahlman M T; Gray M P; Falconieri M W; Whitsett J A; Weaver T E
Lamellar body formation in normal and surfactant protein B-deficient fetal mice.
Laboratory investigation; a journal of technical methods and pathology 2000;80(3):395-403.
2000: Beck D C; Na C L; Whitsett J A; Weaver T E
Ablation of a critical surfactant protein B intramolecular disulfide bond in transgenic mice.
The Journal of biological chemistry 2000;275(5):3371-6.
2000: Beck D C; Ikegami M; Na C L; Zaltash S; Johansson J; Whitsett J A; Weaver T E
The role of homodimers in surfactant protein B function in vivo.
The Journal of biological chemistry 2000;275(5):3365-70.
1999: Akinbi H T; Bhatt H; Hull W M; Weaver T E
Altered surfactant protein B levels in transgenic mice do not affect clearance of bacteria from the lungs.
Pediatric research 1999;46(5):530-4.
1999: Lin S; Na C L; Akinbi H T; Apsley K S; Whitsett J A; Weaver T E
Surfactant protein B (SP-B) -/- mice are rescued by restoration of SP-B expression in alveolar type II cells but not Clara cells.
The Journal of biological chemistry 1999;274(27):19168-74.
1999: Weaver T E; Beck D C
Use of knockout mice to study surfactant protein structure and function.
Biology of the neonate 1999;76 Suppl 1():15-8.
1998: Weaver T E
Synthesis, processing and secretion of surfactant proteins B and C.
Biochimica et biophysica acta 1998;1408(2-3):173-9.
1997: Tokieda K; Whitsett J A; Clark J C; Weaver T E; Ikeda K; McConnell K B; Jobe A H; Ikegami M; Iwamoto H S
Pulmonary dysfunction in neonatal SP-B-deficient mice.
The American journal of physiology 1997;273(4 Pt 1):L875-82.
1997: Akinbi H T; Breslin J S; Ikegami M; Iwamoto H S; Clark J C; Whitsett J A; Jobe A H; Weaver T E
Rescue of SP-B knockout mice with a truncated SP-B proprotein. Function of the C-terminal propeptide.
The Journal of biological chemistry 1997;272(15):9640-7.
1997: Clark J C; Weaver T E; Iwamoto H S; Ikegami M; Jobe A H; Hull W M; Whitsett J A
Decreased lung compliance and air trapping in heterozygous SP-B-deficient mice.
American journal of respiratory cell and molecular biology 1997;16(1):46-52.
1996: Lin S; Akinbi H T; Breslin J S; Weaver T E
Structural requirements for targeting of surfactant protein B (SP-B) to secretory granules in vitro and in vivo.
The Journal of biological chemistry 1996;271(33):19689-95.
1996: Lin S; Phillips K S; Wilder M R; Weaver T E
Structural requirements for intracellular transport of pulmonary surfactant protein B (SP-B).
Biochimica et biophysica acta 1996;1312(3):177-85.
1996: Holzinger A; Phillips K S; Weaver T E
Single-step purification/solubilization of recombinant proteins: application to surfactant protein B.
BioTechniques 1996;20(5):804-6, 808.
1996: Liu L; Rannels S R; Falconieri M; Phillips K S; Wolpert E B; Weaver T E
The testis isoform of the phosphorylase kinase catalytic subunit (PhK-gammaT) plays a critical role in regulation of glycogen mobilization in developing lung.
The Journal of biological chemistry 1996;271(20):11761-6.
1996: Holzinger A; Dingle S; Bejarano P A; Miller M A; Weaver T E; DiLauro R; Whitsett J A
Monoclonal antibody to thyroid transcription factor-1: production, characterization, and usefulness in tumor diagnosis.
Hybridoma 1996;15(1):49-53.
1995: Holzinger A; Trapnell B C; Weaver T E; Whitsett J A; Iwamoto H S
Intraamniotic administration of an adenoviral vector for gene transfer to fetal sheep and mouse tissues.
Pediatric research 1995;38(6):844-50.
1995: Vorbroker D K; Voorhout W F; Weaver T E; Whitsett J A
Posttranslational processing of surfactant protein C in rat type II cells.
The American journal of physiology 1995;269(6 Pt 1):L727-33.
1995: Whitsett J A; Nogee L M; Weaver T E; Horowitz A D
Human surfactant protein B: structure, function, regulation, and genetic disease.
Physiological reviews 1995;75(4):749-57.
1995: Clark J C; Wert S E; Bachurski C J; Stahlman M T; Stripp B R; Weaver T E; Whitsett J A
Targeted disruption of the surfactant protein B gene disrupts surfactant homeostasis, causing respiratory failure in newborn mice.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(17):7794-8.
1994: Cho F S; Phillips K S; Bogucki B; Weaver T E
Characterization of a rat cDNA clone encoding calcium/calmodulin-dependent protein kinase I.
Biochimica et biophysica acta 1994;1224(1):156-60.
1994: Yei S; Bachurski C J; Weaver T E; Wert S E; Trapnell B C; Whitsett J A
Adenoviral-mediated gene transfer of human surfactant protein B to respiratory epithelial cells.
American journal of respiratory cell and molecular biology 1994;11(3):329-36.
1993: Voorhout W F; Weaver T E; Haagsman H P; Geuze H J; Van Golde L M
Biosynthetic routing of pulmonary surfactant proteins in alveolar type II cells.
Microscopy research and technique 1993;26(5):366-73.
1993: Breslin J S; Phillips K S; Weaver T E
Expression of the cyclin-dependent kinase cdk4 in perinatal and adult rat lung.
American journal of respiratory cell and molecular biology 1993;9(5):533-40.
1993: Cho F S; Phillips K S; Khan S A; Weaver T E
Cloning of the rat cyclin-dependent kinase 4 cDNA: implication in proliferation-dependent expression in rat tissues.
Biochemical and biophysical research communications 1993;191(3):860-5.
1992: Voorhout W F; Veenendaal T; Haagsman H P; Weaver T E; Whitsett J A; van Golde L M; Geuze H J
Intracellular processing of pulmonary surfactant protein B in an endosomal/lysosomal compartment.
The American journal of physiology 1992;263(4 Pt 1):L479-86.
1992: Weaver T E; Lin S; Bogucki B; Dey C
Processing of surfactant protein B proprotein by a cathepsin D-like protease.
The American journal of physiology 1992;263(1 Pt 1):L95-103.
1992: Breslin J S; Weaver T E
Binding, uptake, and localization of surfactant protein B in isolated rat alveolar type II cells.
The American journal of physiology 1992;262(6 Pt 1):L699-707.
1992: Vorbroker D K; Dey C; Weaver T E; Whitsett J A
Surfactant protein C precursor is palmitoylated and associates with subcellular membranes.
Biochimica et biophysica acta 1992;1105(1):161-9.
1991: Weaver T E
Surfactant proteins and SP-D.
American journal of respiratory cell and molecular biology 1991;5(1):4-5.
1991: Nogee L M; Wispé J R; Clark J C; Weaver T E; Whitsett J A
Increased expression of pulmonary surfactant proteins in oxygen-exposed rats.
American journal of respiratory cell and molecular biology 1991;4(2):102-7.
1991: Weaver T E; Whitsett J A
Function and regulation of expression of pulmonary surfactant-associated proteins.
The Biochemical journal 1991;273(Pt 2)():249-64.
1989: Weaver T E; Whitsett J A
Processing of hydrophobic pulmonary surfactant protein B in rat type II cells.
The American journal of physiology 1989;257(2 Pt 1):L100-8.
1989: O'Reilly M A; Weaver T E; Pilot-Matias T J; Sarin V K; Gazdar A F; Whitsett J A
In vitro translation, post-translational processing and secretion of pulmonary surfactant protein B precursors.
Biochimica et biophysica acta 1989;1011(2-3):140-8.
1988: Weaver T E; Sarin V K; Sawtell N; Hull W M; Whitsett J A
Identification of surfactant proteolipid SP-B in human surfactant and fetal lung.
Journal of applied physiology (Bethesda, Md. : 1985) 1988;65(2):982-7.
1988: Weaver T E; Whitsett J A
Structure and function of pulmonary surfactant proteins.
Seminars in perinatology 1988;12(3):213-20.
1988: Glasser S W; Korfhagen T R; Weaver T E; Clark J C; Pilot-Matias T; Meuth J; Fox J L; Whitsett J A
cDNA, deduced polypeptide structure and chromosomal assignment of human pulmonary surfactant proteolipid, SPL(pVal).
The Journal of biological chemistry 1988;263(1):9-12.
1988: Weaver T E
Pulmonary surfactant-associated proteins.
General pharmacology 1988;19(3):361-8.
1987: Whitsett J A; Weaver T E; Clark J C; Sawtell N; Glasser S W; Korfhagen T R; Hull W M
Glucocorticoid enhances surfactant proteolipid Phe and pVal synthesis and RNA in fetal lung.
The Journal of biological chemistry 1987;262(32):15618-23.
1986: Whitsett J A; Hull W M; Ohning B; Ross G; Weaver T E
Immunologic identification of a pulmonary surfactant-associated protein of molecular weight = 6000 daltons.
Pediatric research 1986;20(8):744-9.
1986: Weaver T E; Hull W M; Ross G; Whitsett J A
In vitro acetylation of rat pulmonary surfactant-associated glycoprotein(s) A primary translation products.
Biochimica et biophysica acta 1986;869(3):330-6.
1985: Weaver T E; Whitsett J A; Hull W M; Ross G
Identification of canine pulmonary surfactant-associated glycoprotein A precursors.
Journal of applied physiology (Bethesda, Md. : 1985) 1985;58(6):2091-5.
1985: Weaver T E; Hull W M; Ross G F; Whitsett J A
Intracellular and oligomeric forms of surfactant-associated apolipoproteins(s) A in the rat.
Biochimica et biophysica acta 1985;827(3):260-7.

Sign-in to see more