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Claudia Brandt

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Marta Rattka; Claudia Brandt; Wolfgang Löscher
The intrahippocampal kainate model of temporal lobe epilepsy revisited: epileptogenesis, behavioral and cognitive alterations, pharmacological response, and hippoccampal damage in epileptic rats.
Marta Rattka; Claudia Brandt; Wolfgang Löscher
Do proconvulsants modify or halt epileptogenesis? Pentylenetetrazole is ineffective in two rat models of temporal lobe epilepsy.
Melanie Langer; Claudia Brandt; Christina Zellinger; Wolfgang Löscher
Therapeutic window of opportunity for the neuroprotective effect of valproate versus the competitive AMPA receptor antagonist NS1209 following status epilepticus in rats.

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All Publications

2013: Marta Rattka; Claudia Brandt; Wolfgang Löscher
The intrahippocampal kainate model of temporal lobe epilepsy revisited: epileptogenesis, behavioral and cognitive alterations, pharmacological response, and hippoccampal damage in epileptic rats.
Epilepsy research 2013;103(2-3):135-52.
2012: Marta Rattka; Claudia Brandt; Wolfgang Löscher
Do proconvulsants modify or halt epileptogenesis? Pentylenetetrazole is ineffective in two rat models of temporal lobe epilepsy.
The European journal of neuroscience 2012;36(4):2505-20.
2011: Melanie Langer; Claudia Brandt; Christina Zellinger; Wolfgang Löscher
Therapeutic window of opportunity for the neuroprotective effect of valproate versus the competitive AMPA receptor antagonist NS1209 following status epilepticus in rats.
Neuropharmacology 2011;61(5-6):1033-47.
2011: Melanie Langer; Claudia Brandt; Wolfgang Löscher
Marked strain and substrain differences in induction of status epilepticus and subsequent development of neurodegeneration, epilepsy, and behavioral alterations in rats. [corrected].
Epilepsy research 2011;96(3):207-24.
2011: Marta Rattka; Claudia Brandt; Marion Bankstahl; Sonja Bröer; Wolfgang Löscher
Enhanced susceptibility to the GABA antagonist pentylenetetrazole during the latent period following a pilocarpine-induced status epilepticus in rats.
Neuropharmacology 2011;60(2-3):505-12.
2010: Wolfgang Löscher; Claudia Brandt
Prevention or modification of epileptogenesis after brain insults: experimental approaches and translational research.
Pharmacological reviews 2010;62(4):668-700.
2010: Claudia Brandt; Maia Nozadze; Nina Heuchert; Marta Rattka; Wolfgang Löscher
Disease-modifying effects of phenobarbital and the NKCC1 inhibitor bumetanide in the pilocarpine model of temporal lobe epilepsy.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(25):8602-12.
2010: Wolfgang Löscher; Claudia Brandt
High seizure frequency prior to antiepileptic treatment is a predictor of pharmacoresistant epilepsy in a rat model of temporal lobe epilepsy.
Epilepsia 2010;51(1):89-97.
2009: Konstantin Kuteykin-Teplyakov; Claudia Brandt; Katrin Hoffmann; Wolfgang Löscher
Complex time-dependent alterations in the brain expression of different drug efflux transporter genes after status epilepticus.
Epilepsia 2009;50(4):887-97.
2008: Alexandra M Gastens; Claudia Brandt; Jens Bankstahl; Wolfgang Löscher
Predictors of pharmacoresistant epilepsy: pharmacoresistant rats differ from pharmacoresponsive rats in behavioral and cognitive abnormalities associated with experimentally induced epilepsy.
Epilepsia 2008;49(10):1759-76.
2008: Kerstin Bethmann; Jean-Marc Fritschy; Claudia Brandt; Wolfgang Löscher
Antiepileptic drug resistant rats differ from drug responsive rats in GABA A receptor subunit expression in a model of temporal lobe epilepsy.
Neurobiology of disease 2008;31(2):169-87.
2007: Claudia Brandt; Maike Glien; Alexandra M Gastens; Maren Fedrowitz; Kerstin Bethmann; Holger Volk; Heidrun Potschka; Wolfgang Löscher
Prophylactic treatment with levetiracetam after status epilepticus: lack of effect on epileptogenesis, neuronal damage, and behavioral alterations in rats.
Neuropharmacology 2007;53(2):207-21.
2007: Kerstin Bethmann; Claudia Brandt; Wolfgang Löscher
Resistance to phenobarbital extends to phenytoin in a rat model of temporal lobe epilepsy.
Epilepsia 2007;48(4):816-26.
2006: Claudia Brandt; Anna Heile; Heidrun Potschka; Thomas Stoehr; Wolfgang Löscher
Effects of the novel antiepileptic drug lacosamide on the development of amygdala kindling in rats.
Epilepsia 2006;47(11):1803-9.
2006: Claudia Brandt; Kerstin Bethmann; Alexandra M Gastens; Wolfgang Löscher
The multidrug transporter hypothesis of drug resistance in epilepsy: Proof-of-principle in a rat model of temporal lobe epilepsy.
Neurobiology of disease 2006;24(1):202-11.
2006: Christian Freichel; Heidrun Potschka; Ulrich Ebert; Claudia Brandt; Wolfgang Löscher
Acute changes in the neuronal expression of GABA and glutamate decarboxylase isoforms in the rat piriform cortex following status epilepticus.
Neuroscience 2006;141(4):2177-94.
2006: Claudia Brandt; Alexandra M Gastens; Mei zhen Sun; Maria Hausknecht; Wolfgang Löscher
Treatment with valproate after status epilepticus: effect on neuronal damage, epileptogenesis, and behavioral alterations in rats.
Neuropharmacology 2006;51(4):789-804.
2006: Holger Volk; Dimitrula Arabadzisz; Jean-Marc Fritschy; Claudia Brandt; Kerstin Bethmann; Wolfgang Löscher
Antiepileptic drug-resistant rats differ from drug-responsive rats in hippocampal neurodegeneration and GABA(A) receptor ligand binding in a model of temporal lobe epilepsy.
Neurobiology of disease 2006;21(3):633-46.
2004: Claudia Brandt; Ulrich Ebert; Wolfgang Löscher
Epilepsy induced by extended amygdala-kindling in rats: lack of clear association between development of spontaneous seizures and neuronal damage.
Epilepsy research 2004;62(2-3):135-56.
2004: Claudia Brandt; Holger Volk; Wolfgang Löscher
Striking differences in individual anticonvulsant response to phenobarbital in rats with spontaneous seizures after status epilepticus.
Epilepsia 2004;45(12):1488-97.
2003: Claudia Brandt; Maike Glien; Heidrun Potschka; Holger Volk; Wolfgang Löscher
Epileptogenesis and neuropathology after different types of status epilepticus induced by prolonged electrical stimulation of the basolateral amygdala in rats.
Epilepsy research 2003;55(1-2):83-103.
2003: Claudia Brandt; Heidrun Potschka; Wolfgang Löscher; Ulrich Ebert
N-methyl-D-aspartate receptor blockade after status epilepticus protects against limbic brain damage but not against epilepsy in the kainate model of temporal lobe epilepsy.
Neuroscience 2003;118(3):727-40.
2002: Maike Glien; Claudia Brandt; Heidrun Potschka; Wolfgang Löscher
Effects of the novel antiepileptic drug levetiracetam on spontaneous recurrent seizures in the rat pilocarpine model of temporal lobe epilepsy.
Epilepsia 2002;43(4):350-7.
2002: Ulrich Ebert; Claudia Brandt; Wolfgang Löscher
Delayed sclerosis, neuroprotection, and limbic epileptogenesis after status epilepticus in the rat.
Epilepsia 2002;43 Suppl 5():86-95.
2001: Maike Glien; Claudia Brandt; Heidrun Potschka; H Voigt; Ulrich Ebert; Wolfgang Löscher
Repeated low-dose treatment of rats with pilocarpine: low mortality but high proportion of rats developing epilepsy.
Epilepsy research 2001;46(2):111-9.