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Ulrich Brandt

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Tobias A Weber; Ilka Wittig; Alexander van der Bliek; Ulrich Brandt; Brian Head; Heinrich Heide; Sebastian Koob; Michel Mittelbronn; Andreas S Reichert
APOOL Is a Cardiolipin-Binding Constituent of the Mitofilin/MINOS Protein Complex Determining Cristae Morphology in Mammalian Mitochondria.
Qiuqin Zhou; James Baum; Ulrich Brandt; Andrea Dowling; Richard H ffrench-Constant; Heinrich Heide; Jens Wöhnert; Helge B Bode
Xentrivalpeptides A-Q: depsipeptide diversification in Xenorhabdus.
Heinrich Heide; Ina Koch; Andreas S Reichert; Bettina Schwamb; Mirco Steger; Ilka Wittig; Martin Zörnig; Jörg Ackermann; Lea Bleier; Stefan Dröse; Ulrich Brandt
Complexome profiling identifies TMEM126B as a component of the mitochondrial complex I assembly complex.

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2013: Tobias A Weber; Ilka Wittig; Alexander van der Bliek; Ulrich Brandt; Brian Head; Heinrich Heide; Sebastian Koob; Michel Mittelbronn; Andreas S Reichert
APOOL Is a Cardiolipin-Binding Constituent of the Mitofilin/MINOS Protein Complex Determining Cristae Morphology in Mammalian Mitochondria.
PloS one 2013;8(5):e63683.
2012: Qiuqin Zhou; James Baum; Ulrich Brandt; Andrea Dowling; Richard H ffrench-Constant; Heinrich Heide; Jens Wöhnert; Helge B Bode
Xentrivalpeptides A-Q: depsipeptide diversification in Xenorhabdus.
Journal of natural products 2012;75(10):1717-22.
2012: Heinrich Heide; Ina Koch; Andreas S Reichert; Bettina Schwamb; Mirco Steger; Ilka Wittig; Martin Zörnig; Jörg Ackermann; Lea Bleier; Stefan Dröse; Ulrich Brandt
Complexome profiling identifies TMEM126B as a component of the mitochondrial complex I assembly complex.
Cell metabolism 2012;16(4):538-49.
2012: Heike Angerer; Stefan Kerscher; Hamid R Nasiri; Vanessa Niedergesäß; Harald Schwalbe; Ulrich Brandt
Tracing the tail of ubiquinone in mitochondrial complex I.
Biochimica et biophysica acta 2012;1817(10):1776-84.
2012: Georg Auburger; Ulrich Brandt; Vania Broccoli; Jessica Drost; Suzana Gispert; Michael Klinkenberg; Wolfram S Kunz; Katrin Marcus; Blas Morales-Gordo; Heinz Reichmann; Marina Jendrach
Primary skin fibroblasts as a model of Parkinson's disease.
Molecular neurobiology 2012;46(1):20-7.
2012: Reynir Scheving; Mirco Steger; Boris Albuquerque; Ulrich Brandt; Heinrich Heide; Ilka Wittig; Irmgard Tegeder
Protein S-nitrosylation and denitrosylation in the mouse spinal cord upon injury of the sciatic nerve.
Journal of proteomics 2012;75(13):3987-4004.
2012: Kristina Leuner; Sören Mai; Angelo Occhipinti; Richard D Palmiter; Andreas S Reichert; Carola Schiller; Tanja Schütt; Michael Willem; Ilka Wittig; Ulrich Brandt; Stefan Dröse; Gunter P Eckert; Schamim H Eckert; Christian Haass; Marina Jendrach; Shane E Kruse; Christopher Kurz; Walter E Müller
Mitochondrion-derived reactive oxygen species lead to enhanced amyloid beta formation.
Antioxidants & redox signaling 2012;16(12):1421-33.
2012: Stefan Dröse; Ulrich Brandt
Molecular mechanisms of superoxide production by the mitochondrial respiratory chain.
Advances in experimental medicine and biology 2012;748():145-69.
2011: Andrea Weil; Ilka Wittig; Ulrich Brandt; Stefan Dröse; Karin Luce; Heinz D Osiewacz
Unmasking a temperature-dependent effect of the P. anserina i-AAA protease on aging and development.
Cell cycle (Georgetown, Tex.) 2011;10(24):4280-90.
2011: Stefan Dröse; Heinrich Heide; Stefan Kerscher; Stephanie Krack; Nina Morgner; Esther Nübel; Michael Radermacher; Lucie Sokolova; Mirco Steger; Volker Zickermann; Klaus Zwicker; Hans-Dieter Barth; Bernhard Brutschy; Ulrich Brandt
Functional dissection of the proton pumping modules of mitochondrial complex I.
PLoS biology 2011;9(8):e1001128.
2011: Heike Angerer; Ulrich Brandt; Bernhard Brutschy; Heinrich Heide; Silke Kaiser; Esther Nübel; Michael Radermacher; Lucie Sokolova; Mirco Steger; Zibiernisha Wumaier; Klaus Zwicker; Volker Zickermann
A scaffold of accessory subunits links the peripheral arm and the distal proton-pumping module of mitochondrial complex I.
The Biochemical journal 2011;437(2):279-88.
2011: Stefan Dröse; Lea Bleier; Ulrich Brandt
A common mechanism links differently acting complex II inhibitors to cardioprotection: modulation of mitochondrial reactive oxygen species production.
Molecular pharmacology 2011;79(5):814-22.
2010: Maja A Tocilescu; Volker Zickermann; Klaus Zwicker; Ulrich Brandt
Quinone binding and reduction by respiratory complex I.
Biochimica et biophysica acta 2010;1797(12):1883-90.
2010: Volker Zickermann; Heike Angerer; Martina G Ding; Esther Nübel; Ulrich Brandt
Small single transmembrane domain (STMD) proteins organize the hydrophobic subunits of large membrane protein complexes.
FEBS letters 2010;584(12):2516-25.
2010: Maja A Tocilescu; Uta Fendel; Klaus Zwicker; Stefan Dröse; Stefan Kerscher; Ulrich Brandt
The role of a conserved tyrosine in the 49-kDa subunit of complex I for ubiquinone binding and reduction.
Biochimica et biophysica acta 2010;1797(6-7):625-32.
2010: Lucie Sokolova; Ilka Wittig; Hans-Dieter Barth; Hermann Schägger; Bernhard Brutschy; Ulrich Brandt
Laser-induced liquid bead ion desorption-MS of protein complexes from blue-native gels, a sensitive top-down proteomic approach.
Proteomics 2010;10(7):1401-7.
2010: Sevdalina Lyubenova; Thorsten Maly; Klaus Zwicker; Ulrich Brandt; Bernd Ludwig; Thomas Prisner
Multifrequency pulsed electron paramagnetic resonance on metalloproteins.
Accounts of chemical research 2010;43(2):181-9.
2010: Krzysztof Dobrynin; Albina Abdrakhmanova; Sebastian Richers; Carola Hunte; Stefan Kerscher; Ulrich Brandt
Characterization of two different acyl carrier proteins in complex I from Yarrowia lipolytica.
Biochimica et biophysica acta 2010;1797(2):152-9.
2010: T Clason; Teresa Ruiz; H Schägger; G Peng; Volker Zickermann; Ulrich Brandt; H Michel; Michael Radermacher
The structure of eukaryotic and prokaryotic complex I.
Journal of structural biology 2010;169(1):81-8.
2010: Dmitry Namgaladze; Stefan Preiss; Stefan Dröse; Ulrich Brandt; Bernhard Brüne
Phospholipase A2-modified low density lipoprotein induces mitochondrial uncoupling and lowers reactive oxygen species in phagocytes.
Atherosclerosis 2010;208(1):142-7.
2009: Susanne Hauptmann; Isabel Scherping; Stefan Dröse; Ulrich Brandt; Kathrin Boergel; Marina Jendrach; Kristina Leuner; Anne Eckert; Walter E Müller
Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice.
Neurobiology of aging 2009;30(10):1574-86.
2009: Volker Zickermann; Stefan Kerscher; Klaus Zwicker; Maja A Tocilescu; Michael Radermacher; Ulrich Brandt
Architecture of complex I and its implications for electron transfer and proton pumping.
Biochimica et biophysica acta 2009;1787(6):574-83.
2009: Thorsten Maly; Klaus Zwicker; Adrian Cernescu; Ulrich Brandt; Thomas F Prisner
New pulsed EPR methods and their application to characterize mitochondrial complex I.
Biochimica et biophysica acta 2009;1787(6):584-92.
2009: Stefan Dröse; Peter J Hanley; Ulrich Brandt
Ambivalent effects of diazoxide on mitochondrial ROS production at respiratory chain complexes I and III.
Biochimica et biophysica acta 2009;1790(6):558-65.
2009: Judith Haendeler; Stefan Dröse; Nicole Büchner; Sascha Jakob; Joachim Altschmied; Christine Goy; Ioakim Spyridopoulos; Andreas M Zeiher; Ulrich Brandt; Stefanie Dimmeler
Mitochondrial telomerase reverse transcriptase binds to and protects mitochondrial DNA and function from damage.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(6):929-35.
2009: Esther Nübel; Ilka Wittig; Stefan Kerscher; Ulrich Brandt; Hermann Schägger
Two-dimensional native electrophoretic analysis of respiratory supercomplexes from Yarrowia lipolytica.
Proteomics 2009;9(9):2408-18.
2009: Ulf Abdel-Rahman; Petar S Risteski; K Tizi; Stefan Kerscher; S Behjati; S Bejati; Klaus Zwicker; Martin Scholz; Ulrich Brandt; Anton Moritz
Hypoxic reoxygenation during initial reperfusion attenuates cardiac dysfunction and limits ischemia-reperfusion injury after cardioplegic arrest in a porcine model.
The Journal of thoracic and cardiovascular surgery 2009;137(4):978-82.
2009: Stefan Dröse; Alexander Galkin; Ulrich Brandt
Chapter 26 Measurement of superoxide formation by mitochondrial complex I of Yarrowia lipolytica.
Methods in enzymology 2009;456():475-90.
2008: Anne Eckert; Susanne Hauptmann; Isabel Scherping; Jessica Meinhardt; Virginie Rhein; Stefan Dröse; Ulrich Brandt; Marcus Fändrich; Walter E Müller; Jürgen Götz
Oligomeric and fibrillar species of beta-amyloid (A beta 42) both impair mitochondrial function in P301L tau transgenic mice.
Journal of molecular medicine (Berlin, Germany) 2008;86(11):1255-67.
2008: Volker Zickermann; Stefan Dröse; Maja A Tocilescu; Klaus Zwicker; Stefan Kerscher; Ulrich Brandt
Challenges in elucidating structure and mechanism of proton pumping NADH:ubiquinone oxidoreductase (complex I).
Journal of bioenergetics and biomembranes 2008;40(5):475-83.
2008: Nina Morgner; Volker Zickermann; Stefan Kerscher; Ilka Wittig; Albina Abdrakhmanova; Hans-Dieter Barth; Bernhard Brutschy; Ulrich Brandt
Subunit mass fingerprinting of mitochondrial complex I.
Biochimica et biophysica acta 2008;1777(10):1384-91.
2008: Stefan Dröse; Ulrich Brandt
The mechanism of mitochondrial superoxide production by the cytochrome bc1 complex.
The Journal of biological chemistry 2008;283(31):21649-54.
2008: Alexander Galkin; Björn Meyer; Ilka Wittig; Michael Karas; Hermann Schägger; Andrei Vinogradov; Ulrich Brandt
Identification of the mitochondrial ND3 subunit as a structural component involved in the active/deactive enzyme transition of respiratory complex I.
The Journal of biological chemistry 2008;283(30):20907-13.
2008: Uta Fendel; Maja A Tocilescu; Stefan Kerscher; Ulrich Brandt
Exploring the inhibitor binding pocket of respiratory complex I.
Biochimica et biophysica acta 2008;1777(7-8):660-5.
2008: Stefan Kerscher; Stefan Dröse; Volker Zickermann; Ulrich Brandt
The three families of respiratory NADH dehydrogenases.
Results and problems in cell differentiation 2008;45():185-222.
2007: Maja A Tocilescu; Uta Fendel; Klaus Zwicker; Stefan Kerscher; Ulrich Brandt
Exploring the ubiquinone binding cavity of respiratory complex I.
The Journal of biological chemistry 2007;282(40):29514-20.
2007: Todd Clason; Volker Zickermann; Teresa Ruiz; Ulrich Brandt; Michael Radermacher
Direct localization of the 51 and 24 kDa subunits of mitochondrial complex I by three-dimensional difference imaging.
Journal of structural biology 2007;159(3):433-42.
2007: Mathias Soller; Stefan Dröse; Ulrich Brandt; Bernhard Brüne; Andreas von Knethen
Mechanism of thiazolidinedione-dependent cell death in Jurkat T cells.
Molecular pharmacology 2007;71(6):1535-44.
2007: Volker Zickermann; Klaus Zwicker; Maja A Tocilescu; Stefan Kerscher; Ulrich Brandt
Characterization of a subcomplex of mitochondrial NADH:ubiquinone oxidoreductase (complex I) lacking the flavoprotein part of the N-module.
Biochimica et biophysica acta 2007;1767(5):393-400.
2007: Hans-Hermann Hoepken; Suzana Gispert; Blas Morales; Oliver Wingerter; Domenico Del Turco; Alexander Mülsch; Robert L Nussbaum; Klaus Müller; Stefan Dröse; Ulrich Brandt; Thomas Deller; Brunhilde Wirth; Alexei P Kudin; Wolfram S Kunz; Georg Auburger
Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6.
Neurobiology of disease 2007;25(2):401-11.
2006: Aurelio Garofano; Andrea Eschemann; Ulrich Brandt; Stefan Kerscher
Substrate-inducible versions of internal alternative NADH: ubiquinone oxidoreductase from Yarrowia lipolytica.
Yeast (Chichester, England) 2006;23(16):1129-36.
2006: Alexander Galkin; Stefan Dröse; Ulrich Brandt
The proton pumping stoichiometry of purified mitochondrial complex I reconstituted into proteoliposomes.
Biochimica et biophysica acta 2006;1757(12):1575-81.
2006: Albina Abdrakhmanova; Klaus Zwicker; Stefan Kerscher; Volker Zickermann; Ulrich Brandt
Tight binding of NADPH to the 39-kDa subunit of complex I is not required for catalytic activity but stabilizes the multiprotein complex.
Biochimica et biophysica acta 2006;1757(12):1676-82.
2006: Stefan Dröse; Ulrich Brandt; Peter J Hanley
K+-independent actions of diazoxide question the role of inner membrane KATP channels in mitochondrial cytoprotective signaling.
The Journal of biological chemistry 2006;281(33):23733-9.
2006: Marina A Schwab; Sven W Sauer; Jürgen G Okun; Leo G J Nijtmans; Richard J T Rodenburg; Lambert P van den Heuvel; Stefan Dröse; Ulrich Brandt; Georg F Hoffmann; Henk ter Laak; Stefan Kölker; Jan A M Smeitink
Secondary mitochondrial dysfunction in propionic aciduria: a pathogenic role for endogenous mitochondrial toxins.
The Biochemical journal 2006;398(1):107-12.
2006: Klaus Zwicker; Alexander Galkin; Stefan Dröse; Ljuban Grgic; Stefan Kerscher; Ulrich Brandt
The Redox-Bohr group associated with iron-sulfur cluster N2 of complex I.
The Journal of biological chemistry 2006;281(32):23013-7.
2006: Michael Radermacher; Teresa Ruiz; T Clason; S Benjamin; Ulrich Brandt; Volker Zickermann
The three-dimensional structure of complex I from Yarrowia lipolytica: a highly dynamic enzyme.
Journal of structural biology 2006;154(3):269-79.
2006: Douglas Marshall; Nicholas Fisher; Ljuban Grigic; Volker Zickermann; Ulrich Brandt; Richard J Shannon; Judy Hirst; Rebecca Lawrence; Peter R Rich
ATR-FTIR redox difference spectroscopy of Yarrowia lipolytica and bovine complex I.
Biochemistry 2006;45(17):5458-67.
2006: Thorsten Maly; Ljuban Grgic; Klaus Zwicker; Volker Zickermann; Ulrich Brandt; Thomas F Prisner
Cluster N1 of complex I from Yarrowia lipolytica studied by pulsed EPR spectroscopy.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2006;11(3):343-50.
2006: Romain A Duval; Guy Lewin; Eva Peris; Nadia Chahboune; Aurelio Garofano; Stefan Dröse; Diego Cortes; Ulrich Brandt; Reynald Hocquemiller
Heterocyclic analogues of squamocin as inhibitors of mitochondrial complex I. On the role of the terminal lactone of annonaceous acetogenins.
Biochemistry 2006;45(8):2721-8.
2006: Séverine Derbré; Romain A Duval; Gaël Roué; Aurelio Garofano; Erwan Poupon; Ulrich Brandt; Santos A Susin; Reynald Hocquemiller
Semisynthesis and screening of a small library of pro-apoptotic squamocin analogues: selection and study of a benzoquinone hybrid with an improved biological profile.
ChemMedChem 2006;1(1):118-29.
2006: Ulrich Brandt
Energy converting NADH:quinone oxidoreductase (complex I).
Annual review of biochemistry 2006;75():69-92.
2005: Stefan Dröse; Alexander Galkin; Ulrich Brandt
Proton pumping by complex I (NADH:ubiquinone oxidoreductase) from Yarrowia lipolytica reconstituted into proteoliposomes.
Biochimica et biophysica acta 2005;1710(2-3):87-95.
2005: Albina Abdrakhmanova; Krzysztof Dobrynin; Klaus Zwicker; Stefan Kerscher; Ulrich Brandt
Functional sulfurtransferase is associated with mitochondrial complex I from Yarrowia lipolytica, but is not required for assembly of its iron-sulfur clusters.
FEBS letters 2005;579(30):6781-5.
2005: Romain A Duval; Erwan Poupon; Ulrich Brandt; Reynald Hocquemiller
Remarkable substituent effect: beta-aminosquamocin, a potent dual inhibitor of mitochondrial complexes I and III.
Biochimica et biophysica acta 2005;1709(3):191-4.
2005: Alexander Galkin; Ulrich Brandt
Superoxide radical formation by pure complex I (NADH:ubiquinone oxidoreductase) from Yarrowia lipolytica.
The Journal of biological chemistry 2005;280(34):30129-35.
2005: Ulrich Brandt; Albina Abdrakhmanova; Volker Zickermann; Alexander Galkin; Stefan Dröse; Klaus Zwicker; Stefan Kerscher
Structure-function relationships in mitochondrial complex I of the strictly aerobic yeast Yarrowia lipolytica.
Biochemical Society transactions 2005;33(Pt 4):840-4.
2005: Della C David; Susanne Hauptmann; Isabel Scherping; Katrin Schuessel; Uta Keil; Patrizia Rizzu; Rivka Ravid; Stefan Dröse; Ulrich Brandt; Walter E Müller; Anne Eckert; Jürgen Götz
Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice.
The Journal of biological chemistry 2005;280(25):23802-14.
2005: Antje Waletko; Klaus Zwicker; Albina Abdrakhmanova; Volker Zickermann; Ulrich Brandt; Stefan Kerscher
Histidine 129 in the 75-kDa subunit of mitochondrial complex I from Yarrowia lipolytica is not a ligand for [Fe4S4] cluster N5 but is required for catalytic activity.
The Journal of biological chemistry 2005;280(7):5622-5.
2005: Andrea Eschemann; Alexander Galkin; Walter Oettmeier; Ulrich Brandt; Stefan Kerscher
HDQ (1-hydroxy-2-dodecyl-4(1H)quinolone), a high affinity inhibitor for mitochondrial alternative NADH dehydrogenase: evidence for a ping-pong mechanism.
The Journal of biological chemistry 2005;280(5):3138-42.
2005: Peter J Hanley; Stefan Dröse; Ulrich Brandt; Rachel A Lareau; Abir L Banerjee; DK Srivastava; Leonard J Banaszak; Joseph J Barycki; Paul P Van Veldhoven; Jürgen Daut
5-Hydroxydecanoate is metabolised in mitochondria and creates a rate-limiting bottleneck for beta-oxidation of fatty acids.
The Journal of physiology 2005;562(Pt 2):307-18.
2004: Stefan Kerscher; Ljuban Grgic; Aurelio Garofano; Ulrich Brandt
Application of the yeast Yarrowia lipolytica as a model to analyse human pathogenic mutations in mitochondrial complex I (NADH:ubiquinone oxidoreductase).
Biochimica et biophysica acta 2004;1659(2-3):197-205.
2004: Alexandra Keller; Annisuddin Mohamed; Stefan Dröse; Ulrich Brandt; Ingrid Fleming; Ralf P Brandes
Analysis of dichlorodihydrofluorescein and dihydrocalcein as probes for the detection of intracellular reactive oxygen species.
Free radical research 2004;38(12):1257-67.
2004: Stefan Kerscher; Paule Bénit; Albina Abdrakhmanova; Klaus Zwicker; Isam Rais; Michael Karas; Pierre Rustin; Ulrich Brandt
Processing of the 24 kDa subunit mitochondrial import signal is not required for assembly of functional complex I in Yarrowia lipolytica.
European journal of biochemistry / FEBS 2004;271(17):3588-95.
2004: Hermann Schägger; René de Coo; Matthias F Bauer; Sabine Hofmann-Thiel; Catherine Godinot; Ulrich Brandt
Significance of respirasomes for the assembly/stability of human respiratory chain complex I.
The Journal of biological chemistry 2004;279(35):36349-53.
2004: Albina Abdrakhmanova; Volker Zickermann; Mihnea Bostina; Michael Radermacher; Hermann Schägger; Stefan Kerscher; Ulrich Brandt
Subunit composition of mitochondrial complex I from the yeast Yarrowia lipolytica.
Biochimica et biophysica acta 2004;1658(1-2):148-56.
2004: Ljuban Grgic; Klaus Zwicker; Noushin Kashani-Poor; Stefan Kerscher; Ulrich Brandt
Functional significance of conserved histidines and arginines in the 49-kDa subunit of mitochondrial complex I.
The Journal of biological chemistry 2004;279(20):21193-9.
2004: Thorsten Maly; Fraser MacMillan; Klaus Zwicker; Noushin Kashani-Poor; Ulrich Brandt; Thomas F Prisner
Relaxation filtered hyperfine (REFINE) spectroscopy: a novel tool for studying overlapping biological electron paramagnetic resonance signals applied to mitochondrial complex I.
Biochemistry 2004;43(13):3969-78.
2004: Takeshi Hamada; Naoya Ichimaru; Masato Abe; Daisuke Fujita; Atsushi Kenmochi; Takaaki Nishioka; Klaus Zwicker; Ulrich Brandt; Hideto Miyoshi
Synthesis and inhibitory action of novel acetogenin mimics with bovine heart mitochondrial complex I.
Biochemistry 2004;43(12):3651-8.
2003: Kathy Pfeiffer; VISHAL GOHIL; Rosemary A Stuart; Carola Hunte; Ulrich Brandt; Miriam L. Greenberg; Hermann Schägger
Cardiolipin stabilizes respiratory chain supercomplexes.
The Journal of biological chemistry 2003;278(52):52873-80.
2003: Aurelio Garofano; Klaus Zwicker; Stefan Kerscher; Pamela Okun; Ulrich Brandt
Two aspartic acid residues in the PSST-homologous NUKM subunit of complex I from Yarrowia lipolytica are essential for catalytic activity.
The Journal of biological chemistry 2003;278(43):42435-40.
2003: Hélène Simonnet; Jocelyne Demont; Kathy Pfeiffer; Leila Guenaneche; Raymonde Bouvier; Ulrich Brandt; Hermann Schagger; Catherine Godinot
Mitochondrial complex I is deficient in renal oncocytomas.
Carcinogenesis 2003;24(9):1461-6.
2003: Volker Zickermann; Mihnea Bostina; Carola Hunte; Teresa Ruiz; Michael Radermacher; Ulrich Brandt
Functional implications from an unexpected position of the 49-kDa subunit of NADH:ubiquinone oxidoreductase.
The Journal of biological chemistry 2003;278(31):29072-8.
2003: Ulrich Brandt; Stefan Kerscher; Stefan Dröse; Klaus Zwicker; Volker Zickermann
Proton pumping by NADH:ubiquinone oxidoreductase. A redox driven conformational change mechanism?
FEBS letters 2003;545(1):9-17.
2002: Peter J Hanley; John Ray; Ulrich Brandt; Jürgen Daut
Halothane, isoflurane and sevoflurane inhibit NADH:ubiquinone oxidoreductase (complex I) of cardiac mitochondria.
The Journal of physiology 2002;544(Pt 3):687-93.
2002: Stefan Dröse; Klaus Zwicker; Ulrich Brandt
Full recovery of the NADH:ubiquinone activity of complex I (NADH:ubiquinone oxidoreductase) from Yarrowia lipolytica by the addition of phospholipids.
Biochimica et biophysica acta 2002;1556(1):65-72.
2002: Stefan Kerscher; Stefan Dröse; Klaus Zwicker; Volker Zickermann; Ulrich Brandt
Yarrowia lipolytica, a yeast genetic system to study mitochondrial complex I.
Biochimica et biophysica acta 2002;1555(1-3):83-91.
2002: Peter J Hanley; Markus Mickel; Monika Löffler; Ulrich Brandt; Jürgen Daut
K(ATP) channel-independent targets of diazoxide and 5-hydroxydecanoate in the heart.
The Journal of physiology 2002;542(Pt 3):735-41.
2001: Stefan Kerscher; Andrea Eschemann; P M Okun; Ulrich Brandt
External alternative NADH:ubiquinone oxidoreductase redirected to the internal face of the mitochondrial inner membrane rescues complex I deficiency in Yarrowia lipolytica.
Journal of cell science 2001;114(Pt 21):3915-21.
2001: Stefan Bartoschek; M Johansson; Bernhard H Geierstanger; J G Okun; Roy Lancaster; E Humpfer; L Yu; C A Yu; Christian Griesinger; Ulrich Brandt
Three molecules of ubiquinone bind specifically to mitochondrial cytochrome bc1 complex.
The Journal of biological chemistry 2001;276(38):35231-4.
2001: Noushin Kashani-Poor; Klaus Zwicker; Stefan Kerscher; Ulrich Brandt
A central functional role for the 49-kDa subunit within the catalytic core of mitochondrial complex I.
The Journal of biological chemistry 2001;276(26):24082-7.
2001: Stefan Kerscher; Noushin Kashani-Poor; Klaus Zwicker; Volker Zickermann; Ulrich Brandt
Exploring the catalytic core of complex I by Yarrowia lipolytica yeast genetics.
Journal of bioenergetics and biomembranes 2001;33(3):187-96.
2001: Noushin Kashani-Poor; Stefan Kerscher; Volker Zickermann; Ulrich Brandt
Efficient large scale purification of his-tagged proton translocating NADH:ubiquinone oxidoreductase (complex I) from the strictly aerobic yeast Yarrowia lipolytica.
Biochimica et biophysica acta 2001;1504(2-3):363-70.
2000: P M Ahlers; Aurelio Garofano; Stefan Kerscher; Ulrich Brandt
Application of the obligate aerobic yeast Yarrowia lipolytica as a eucaryotic model to analyse Leigh syndrome mutations in the complex I core subunits PSST and TYKY.
Biochimica et biophysica acta 2000;1459(2-3):258-65.
2000: P M Ahlers; Klaus Zwicker; Stefan Kerscher; Ulrich Brandt
Function of conserved acidic residues in the PSST homologue of complex I (NADH:ubiquinone oxidoreductase) from Yarrowia lipolytica.
The Journal of biological chemistry 2000;275(31):23577-82.
2000: R Djafarzadeh; Stefan Kerscher; Klaus Zwicker; Michael Radermacher; M Lindahl; Hermann Schägger; Ulrich Brandt
Biophysical and structural characterization of proton-translocating NADH-dehydrogenase (complex I) from the strictly aerobic yeast Yarrowia lipolytica.
Biochimica et biophysica acta 2000;1459(1):230-8.
2000: JG Okun; Volker Zickermann; Klaus Zwicker; Hermann Schägger; Ulrich Brandt
Binding of detergents and inhibitors to bovine complex I - a novel purification procedure for bovine complex I retaining full inhibitor sensitivity.
Biochimica et biophysica acta 2000;1459(1):77-87.
1999: JG Okun; Volker Zickermann; Ulrich Brandt
Properties of the common inhibitor-binding domain in mitochondrial NADH-dehydrogenase (complex I).
Biochemical Society transactions 1999;27(4):596-601.
1999: Stefan Kerscher; JG Okun; Ulrich Brandt
A single external enzyme confers alternative NADH:ubiquinone oxidoreductase activity in Yarrowia lipolytica.
Journal of cell science 1999;112 ( Pt 14)():2347-54.
1999: Ulrich Brandt
Control of ubiquinol oxidation at center P (Qo) of the cytochrome bc1 complex.
Journal of bioenergetics and biomembranes 1999;31(3):243-50.
1999: JG Okun; P Lümmen; Ulrich Brandt
Three classes of inhibitors share a common binding domain in mitochondrial complex I (NADH:ubiquinone oxidoreductase).
The Journal of biological chemistry 1999;274(5):2625-30.
1999: Ulrich Brandt
Proton translocation in the respiratory chain involving ubiquinone--a hypothetical semiquinone switch mechanism for complex I.
BioFactors (Oxford, England) 1999;9(2-4):95-101.
1998: Ulrich Brandt
The chemistry and mechanics of ubihydroquinone oxidation at center P (Qo) of the cytochrome bc1 complex.
Biochimica et biophysica acta 1998;1365(1-2):261-8.
1998: J Ludwig; Stefan Kerscher; Ulrich Brandt; Kathy Pfeiffer; F Getlawi; D K Apps; Hermann Schägger
Identification and characterization of a novel 9.2-kDa membrane sector-associated protein of vacuolar proton-ATPase from chromaffin granules.
The Journal of biological chemistry 1998;273(18):10939-47.
1998: Brigitte Meunier; C Ortwein; Ulrich Brandt; Peter R Rich
Effects of mutation of residue I67 on redox-linked protonation processes in yeast cytochrome c oxidase.
The Biochemical journal 1998;330 ( Pt 3)():1197-200.
1997: Ulrich Brandt; R Djafarzadeh-Andabili
Binding of MOA-stilbene to the mitochondrial cytochrome bc1 complex is affected by the protonation state of a redox-Bohr group of the 'Rieske' iron-sulfur protein.
Biochimica et biophysica acta 1997;1321(3):238-42.
1997: Ulrich Brandt; J G Okun
Role of deprotonation events in ubihydroquinone:cytochrome c oxidoreductase from bovine heart and yeast mitochondria.
Biochemistry 1997;36(37):11234-40.
1997: C Ortwein; T A Link; B Meunier; A M Colson-Corbisier; Peter R Rich; Ulrich Brandt
Structural and functional analysis of deficient mutants in subunit I of cytochrome c oxidase from Saccharomyces cerevisiae.
Biochimica et biophysica acta 1997;1321(1):79-92.
1997: Ulrich Brandt
Proton-translocation by membrane-bound NADH:ubiquinone-oxidoreductase (complex I) through redox-gated ligand conduction.
Biochimica et biophysica acta 1997;1318(1-2):79-91.
1996: Ulrich Brandt
Energy conservation by bifurcated electron-transfer in the cytochrome-bc1 complex.
Biochimica et biophysica acta 1996;1275(1-2):41-6.
1996: Ulrich Brandt
Bifurcated ubihydroquinone oxidation in the cytochrome bc1 complex by proton-gated charge transfer.
FEBS letters 1996;387(1):1-6.
1996: P Kraiczy; U Haase; S Gencic; S Flindt; Timm Anke; Ulrich Brandt; G Von Jagow
The molecular basis for the natural resistance of the cytochrome bc1 complex from strobilurin-producing basidiomycetes to center Qp inhibitors.
European journal of biochemistry / FEBS 1996;235(1-2):54-63.
1995: Hermann Schägger; H Noack; W Halangk; Ulrich Brandt; G von Jagow
Cytochrome-c oxidase in developing rat heart. Enzymic properties and amino-terminal sequences suggest identity of the fetal heart and the adult liver isoform.
European journal of biochemistry / FEBS 1995;230(1):235-41.
1995: B M Geier; Hermann Schägger; C Ortwein; Thomas A Link; Wilfred R Hagen; Ulrich Brandt; G Von Jagow
Kinetic properties and ligand binding of the eleven-subunit cytochrome-c oxidase from Saccharomyces cerevisiae isolated with a novel large-scale purification method.
European journal of biochemistry / FEBS 1995;227(1-2):296-302.
1995: Hermann Schägger; Ulrich Brandt; S Gencic; G von Jagow
Ubiquinol-cytochrome-c reductase from human and bovine mitochondria.
Methods in enzymology 1995;260():82-96.
1994: Ulrich Brandt; S Uribe; Hermann Schägger; Bernard L Trumpower
Isolation and characterization of QCR10, the nuclear gene encoding the 8.5-kDa subunit 10 of the Saccharomyces cerevisiae cytochrome bc1 complex.
The Journal of biological chemistry 1994;269(17):12947-53.
1994: L A Graham; Ulrich Brandt; Bernard L Trumpower
Protease maturation of the Rieske iron-sulphur protein after its insertion into the mitochondrial cytochrome bc1 complex of Saccharomyces cerevisiae.
Biochemical Society transactions 1994;22(1):188-91.
1994: Ulrich Brandt; Bernard L Trumpower
The protonmotive Q cycle in mitochondria and bacteria.
Critical reviews in biochemistry and molecular biology 1994;29(3):165-97.
1993: L A Graham; Ulrich Brandt; J S Sargent; Bernard L Trumpower
Mutational analysis of assembly and function of the iron-sulfur protein of the cytochrome bc1 complex in Saccharomyces cerevisiae.
Journal of bioenergetics and biomembranes 1993;25(3):245-57.
1993: Thomas A Link; U Haase; Ulrich Brandt; G von Jagow
What information do inhibitors provide about the structure of the hydroquinone oxidation site of ubihydroquinone: cytochrome c oxidoreductase?
Journal of bioenergetics and biomembranes 1993;25(3):221-32.
1993: Ulrich Brandt; L Yu; C A Yu; Bernard L Trumpower
The mitochondrial targeting presequence of the Rieske iron-sulfur protein is processed in a single step after insertion into the cytochrome bc1 complex in mammals and retained as a subunit in the complex.
The Journal of biological chemistry 1993;268(12):8387-90.
1992: B M Geier; Hermann Schägger; Ulrich Brandt; A M Colson; G Von Jagow
Point mutation in cytochrome b of yeast ubihydroquinone:cytochrome-c oxidoreductase causing myxothiazol resistance and facilitated dissociation of the iron-sulfur subunit.
European journal of biochemistry / FEBS 1992;208(2):375-80.
1992: Ulrich Brandt; J Schubert; P Geck; G von Jagow
Uncoupling activity and physicochemical properties of derivatives of fluazinam.
Biochimica et biophysica acta 1992;1101(1):41-7.
1991: A John Moody; Ulrich Brandt; P R Rich
Single electron reduction of 'slow' and 'fast' cytochrome-c oxidase.
FEBS letters 1991;293(1-2):101-5.
1991: Ulrich Brandt; U Haase; Hermann Schägger; G von Jagow
Significance of the "Rieske" iron-sulfur protein for formation and function of the ubiquinol-oxidation pocket of mitochondrial cytochrome c reductase (bc1 complex).
The Journal of biological chemistry 1991;266(30):19958-64.
1991: E Lemma; Cecilia Hagerhall; V Geisler; Ulrich Brandt; G von Jagow; Achim Kröger
Reactivity of the Bacillus subtilis succinate dehydrogenase complex with quinones.
Biochimica et biophysica acta 1991;1059(3):281-5.
1991: Ulrich Brandt; G von Jagow
Analysis of the binding of p-chlorophenyl-methoxybenzyl-ketoxime (CPMB-oxime) to mitochondrial cytochrome c reductase.
FEBS letters 1991;287(1-2):215-8.
1991: P R Rich; S A Madgwick; S Brown; G Von Jagow; Ulrich Brandt
MOA-stilbene: a new effector of the Qi site of the chloroplast cytochrome bf complex.
Biochemical Society transactions 1991;19(3):263S.
1991: Ulrich Brandt; G von Jagow
Analysis of inhibitor binding to the mitochondrial cytochrome c reductase by fluorescence quench titration. Evidence for a 'catalytic switch' at the Qo center.
European journal of biochemistry / FEBS 1991;195(1):163-70.
1990: Hermann Schägger; T Hagen; B Roth; Ulrich Brandt; Thomas A Link; G von Jagow
Phospholipid specificity of bovine heart bc1 complex.
European journal of biochemistry / FEBS 1990;190(1):123-30.
1989: Ulrich Brandt; Hermann Schägger; G von Jagow
Purification of cytochrome-c oxidase retaining its pulsed form.
European journal of biochemistry / FEBS 1989;182(3):705-11.
1988: Tomoko Ohnishi; Ulrich Brandt; G von Jagow
Studies on the effect of stigmatellin derivatives on cytochrome b and the Rieske iron-sulfur cluster of cytochrome c reductase from bovine heart mitochondria.
European journal of biochemistry / FEBS 1988;176(2):385-9.
1988: Ulrich Brandt; Hermann Schägger; G von Jagow
Characterisation of binding of the methoxyacrylate inhibitors to mitochondrial cytochrome c reductase.
European journal of biochemistry / FEBS 1988;173(3):499-506.