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Wolfgang Brandt

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Johanna Mansfeld; Wolfgang Brandt; Regine Haftendorn; Regina Schöps; Renate Ulbrich-Hofmann
Discrimination between the regioisomeric 1,2- and 1,3-diacylglycerophosphocholines by phospholipases.
Stefan Biastoff; Nicole Reinhardt; Veaceslav Reva; Wolfgang Brandt; Birgit Dräger
Evolution of putrescine N-methyltransferase from spermidine synthase demanded alterations in substrate binding.
Stefan Biastoff; Wolfgang Brandt; Birgit Dräger
Putrescine N-methyltransferase--the start for alkaloids.

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2011: Johanna Mansfeld; Wolfgang Brandt; Regine Haftendorn; Regina Schöps; Renate Ulbrich-Hofmann
Discrimination between the regioisomeric 1,2- and 1,3-diacylglycerophosphocholines by phospholipases.
Chemistry and physics of lipids 2011;164(3):196-204.
2009: Stefan Biastoff; Nicole Reinhardt; Veaceslav Reva; Wolfgang Brandt; Birgit Dräger
Evolution of putrescine N-methyltransferase from spermidine synthase demanded alterations in substrate binding.
FEBS letters 2009;583(20):3367-74.
2009: Stefan Biastoff; Wolfgang Brandt; Birgit Dräger
Putrescine N-methyltransferase--the start for alkaloids.
Phytochemistry 2009;70(15-16):1708-18.
2008: Jakub Grzegorz Kopycki; Milton T Stubbs; Wolfgang Brandt; Martin Hagemann; Andrea Porzel; Jürgen Schmidt; Willibald Schliemann; Meinhart H Zenk; Thomas Vogt
Functional and structural characterization of a cation-dependent O-methyltransferase from the cyanobacterium Synechocystis sp. strain PCC 6803.
The Journal of biological chemistry 2008;283(30):20888-96.
2008: Anna-Carolin Freydank; Wolfgang Brandt; Birgit Dräger
Protein structure modeling indicates hexahistidine-tag interference with enzyme activity.
Proteins 2008;72(1):173-83.
2008: Andrea Brock; Wolfgang Brandt; Birgit Dräger
The functional divergence of short-chain dehydrogenases involved in tropinone reduction.
The Plant journal : for cell and molecular biology 2008;54(3):388-401.
2008: Sabine Wrenger; Jürgen Faust; Carmen Mrestani-Klaus; Wolfgang Brandt; Anja Thielitz; Klaus Neubert; Dirk Reinhold
Non-substrate peptides influencing dipeptidyl peptidase IV/CD26 activity and immune cell function.
Frontiers in bioscience : a journal and virtual library 2008;13():3194-201.
2003: Susan Lorey; Angela Stöckel-Maschek; Jürgen Faust; Wolfgang Brandt; Beate Stiebitz; mark gorrell; Thilo Kähne; Carmen Mrestani-Klaus; Sabine Wrenger; Dirk Reinhold; Siegfried Ansorge; Klaus Neubert
Different modes of dipeptidyl peptidase IV (CD26) inhibition by oligopeptides derived from the N-terminus of HIV-1 Tat indicate at least two inhibitor binding sites.
European journal of biochemistry / FEBS 2003;270(10):2147-56.
2003: Carmen Mrestani-Klaus; Wolfgang Brandt; Jürgen Faust; Sabine Wrenger; Dirk Reinhold; Siegfried Ansorge; Klaus Neubert
New results on the conformations of potent DP IV (CD26) inhibitors bearing the N-terminal MWP structural motif.
Advances in experimental medicine and biology 2003;524():65-8.
2000: Sabine Wrenger; Jürgen Faust; Carmen Mrestani-Klaus; A Fengler; A Stockel-Maschek; Susan Lorey; T Kahne; Wolfgang Brandt; Klaus Neubert; Siegfried Ansorge; Dirk Reinhold
Down-regulation of T cell activation following inhibition of dipeptidyl peptidase IV/CD26 by the N-terminal part of the thromboxane A2 receptor.
The Journal of biological chemistry 2000;275(29):22180-6.
2000: A Fengler; Wolfgang Brandt
Development and validation of homology models of human cathepsins K, S, H, and F.
Advances in experimental medicine and biology 2000;477():255-60.
2000: Frank Bühling; A Fengler; Wolfgang Brandt; Tobias Welte; Siegfried Ansorge; Dorit Nägler
Review: novel cysteine proteases of the papain family.
Advances in experimental medicine and biology 2000;477():241-54.
2000: Sabine Wrenger; Dirk Reinhold; Jürgen Faust; Carmen Mrestani-Klaus; Wolfgang Brandt; A Fengler; Klaus Neubert; Siegfried Ansorge
Effects of nonapeptides derived from the N-terminal structure of human immunodeficiency virus-1 (HIV-1) Tat on suppression of CD26-dependent T cell growth.
Advances in experimental medicine and biology 2000;477():161-5.
2000: Carmen Mrestani-Klaus; A Fengler; Jürgen Faust; Wolfgang Brandt; Sabine Wrenger; Dirk Reinhold; Siegfried Ansorge; Klaus Neubert
N-terminal HIV-1 Tat nonapeptides as inhibitors of dipeptidyl peptidase IV. Conformational characterization.
Advances in experimental medicine and biology 2000;477():125-9.
2000: Wolfgang Brandt
Development of a tertiary-structure model of the C-terminal domain of DPP IV.
Advances in experimental medicine and biology 2000;477():97-101.
1999: Wolfgang Brandt; Alexander Golbraikh; Michael Täger; Uwe Lendeckel
A molecular mechanism for the cleavage of a disulfide bond as the primary function of agonist binding to G-protein-coupled receptors based on theoretical calculations supported by experiments.
European journal of biochemistry / FEBS 1999;261(1):89-97.
1998: Wolfgang Brandt
A uniform molecular model of delta opioid agonist and antagonist pharmacophore conformations.
Journal of computer-aided molecular design 1998;12(6):615-21.
1998: A Fengler; Wolfgang Brandt
Three-dimensional structures of the cysteine proteases cathepsins K and S deduced by knowledge-based modelling and active site characteristics.
Protein engineering 1998;11(11):1007-13.
1998: Carmen Mrestani-Klaus; A Fengler; Wolfgang Brandt; Jürgen Faust; Sabine Wrenger; Dirk Reinhold; Siegfried Ansorge; Klaus Neubert
1H NMR conformational study on N-terminal nonapeptide sequences of HIV-1 Tat protein: a contribution to structure-activity relationships.
Journal of peptide science : an official publication of the European Peptide Society 1998;4(6):400-10.
1997: Sabine Wrenger; Torsten Hoffmann; Jürgen Faust; Carmen Mrestani-Klaus; Wolfgang Brandt; Klaus Neubert; M Kraft; S Olek; R Frank; Siegfried Ansorge; Dirk Reinhold
The N-terminal structure of HIV-1 Tat is required for suppression of CD26-dependent T cell growth.
The Journal of biological chemistry 1997;272(48):30283-8.
1996: Wolfgang Brandt; M Stoldt; H Schinke
The mu- and delta-opioid pharmacophore conformations of cyclic beta-casomorphin analogues indicate docking of the Phe3 residue to different domains of the opioid receptors.
Journal of computer-aided molecular design 1996;10(3):201-12.
1996: Carmen Mrestani-Klaus; Wolfgang Brandt; R Schmidt; Klaus Neubert; Peter W Schiller
Proton NMR conformational analysis of cyclic beta-casomorphin analogues of the type Tyr-cyclo[N omega-D-Orn-Xaa-Yaa-Gly-].
Archiv der Pharmazie 1996;329(3):133-42.
1996: Wolfgang Brandt; O Ludwig; I Thondorf; A Barth
A new mechanism in serine proteases catalysis exhibited by dipeptidyl peptidase IV (DP IV)--Results of PM3 semiempirical thermodynamic studies supported by experimental results.
European journal of biochemistry / FEBS 1996;236(1):109-14.
1995: Wolfgang Brandt; T Lehmann; I Thondorf; I Born; Mike Schutkowski; Jens-Ulrich Rahfeld; Klaus Neubert; A Barth
A model of the active site of dipeptidyl peptidase IV predicted by comparative molecular field analysis and molecular modelling simulations.
International journal of peptide and protein research 1995;46(6):494-507.
1995: Wolfgang Brandt; T Lehmann; C Willkomm; S Fittkau; A Barth
CoMFA investigations on two series of artificial peptide inhibitors of the serine protease thermitase. Synthesis of an inhibitor of predicted greater potency.
International journal of peptide and protein research 1995;46(1):73-8.
1994: A Barth; K Frost; M Wahab; Wolfgang Brandt; H D Schadler; R Franke
Classification of serine proteases derived from steric comparisons of their active sites, part II: "Ser, His, Asp arrangements in proteolytic and nonproteolytic proteins".
Drug design and discovery 1994;12(2):89-111.
1994: R Schmidt; D Vogel; Carmen Mrestani-Klaus; Wolfgang Brandt; Klaus Neubert; Nga N Chung; Carole Lemieux; Peter W Schiller
Cyclic beta-casomorphin analogues with mixed mu agonist/delta antagonist properties: synthesis, pharmacological characterization, and conformational aspects.
Journal of medicinal chemistry 1994;37(8):1136-44.
1993: Wolfgang Brandt; A Barth
Is the analgesic activity of epibatidine caused by a chemical reaction with the morphine opioid receptor?
SAR and QSAR in environmental research 1993;1(4):345-8.
1993: A Barth; M Wahab; Wolfgang Brandt; K Frost
Classification of serine proteases derived from steric comparisons of their active sites.
Drug design and discovery 1993;10(4):297-317.
1993: Wolfgang Brandt; A Barth; H D Höltje
A new consistent model explaining structure (conformation)-activity relationships of opiates with mu-selectivity.
Drug design and discovery 1993;10(4):257-83.
1992: Wolfgang Brandt; T Lehmann; T Hofmann; R L Schowen; A Barth
The probable conformation of substrates recognized by dipeptidyl-peptidase IV and some aspects of the catalytic mechanism derived from theoretical investigations.
Journal of computer-aided molecular design 1992;6(2):159-74.
1991: D Hübner; B Hartrodt; E Kleinpeter; D Ströhl; Wolfgang Brandt; H Schinke; M Wahab; G Fischer
Conformational analysis of the tetrapeptide Pro-D-Phe-Pro-Gly in aqueous solution.
Biochemical and biophysical research communications 1991;177(1):271-8.