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Heinz-Ulrich Weier

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Benjamin O'Brien; Aris A Polyzos; Mei Wang; Jingly F Weier; Hui Zeng; Horst F Zitzelsberger; Kalistyn H Lemke; Heinz-Ulrich G Weier
Bioinformatics tools allow targeted selection of chromosome enumeration probes and aneuploidy detection.
Joanne H Hsu; Anna R Lawin-O'Brien; Kalistyn H Lemke; Aris A Polyzos; Mei Wang; Heinz-Ulrich G Weier; Jingly F Weier; Hui Zeng; Benjamin O'Brien
Chromosome-specific DNA repeats: rapid identification in silico and validation using fluorescence in situ hybridization.
Natalia Bednarz; Elke Eltze; Axel Semjonow; Michael Rink; Antje Andreas; Lennart Mulder; Juliane Hannemann; Margit Fisch; Klaus Pantel; Heinz-Ulrich G Weier; Krzysztof Piotr Bielawski; Burkhard Brandt
BRCA1 loss preexisting in small subpopulations of prostate cancer is associated with advanced disease and metastatic spread to lymph nodes and peripheral blood.

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2013: Benjamin O'Brien; Aris A Polyzos; Mei Wang; Jingly F Weier; Hui Zeng; Horst F Zitzelsberger; Kalistyn H Lemke; Heinz-Ulrich G Weier
Bioinformatics tools allow targeted selection of chromosome enumeration probes and aneuploidy detection.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2013;61(2):134-47.
2012: Joanne H Hsu; Anna R Lawin-O'Brien; Kalistyn H Lemke; Aris A Polyzos; Mei Wang; Heinz-Ulrich G Weier; Jingly F Weier; Hui Zeng; Benjamin O'Brien
Chromosome-specific DNA repeats: rapid identification in silico and validation using fluorescence in situ hybridization.
International journal of molecular sciences 2012;14(1):57-71.
2010: Natalia Bednarz; Elke Eltze; Axel Semjonow; Michael Rink; Antje Andreas; Lennart Mulder; Juliane Hannemann; Margit Fisch; Klaus Pantel; Heinz-Ulrich G Weier; Krzysztof Piotr Bielawski; Burkhard Brandt
BRCA1 loss preexisting in small subpopulations of prostate cancer is associated with advanced disease and metastatic spread to lymph nodes and peripheral blood.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(13):3340-8.
2009: Heinz-Ulrich G Weier; J Kwan; C-M Lu; Y Ito; M Wang; Adolf Baumgartner; S W Hayward; Jingly F Weier; Horst Zitzelsberger
Kinase expression and chromosomal rearrangements in papillary thyroid cancer tissues: investigations at the molecular and microscopic levels.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2009;60 Suppl 4():47-55.
2009: Chun-Mei Lu; Johnson Kwan; Adolf Baumgartner; Jingly F Weier; Mei Wang; Tomas Escudero; Santiago Munné; Horst F Zitzelsberger; Heinz-Ulrich G Weier
DNA probe pooling for rapid delineation of chromosomal breakpoints.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2009;57(6):587-97.
2009: Chun-Mei Lu; Johnson Kwan; Jingly F Weier; Adolf Baumgartner; Mei Wang; Tomas Escudero; Santiago Munné; Heinz-Ulrich G Weier
Rapid mapping of chromosomal breakpoints: from blood to BAC in 20 days.
Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society 2009;47(3):367-75.
2009: Johnson Kwan; Adolf Baumgartner; Chun-Mei Lu; Mei Wang; Jingly F Weier; Horst Zitzelsberger; Heinz-Ulrich G Weier
BAC-FISH assays delineate complex chromosomal rearrangements in a case of post-Chernobyl childhood thyroid cancer.
Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society 2009;47(2):135-42.
2006: Adolf Baumgartner; Jingly F Weier; Heinz-Ulrich G Weier
Chromosome-specific DNA repeat probes.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2006;54(12):1363-70.
2006: Jingly F Weier; C Ferlatte; Adolf Baumgartner; C J Jung; H-N Nguyen; Lisa W Chu; Roger A Pedersen; Susan J Fisher; Heinz-Ulrich G Weier
Molecular cytogenetic studies towards the full karyotype analysis of human blastocysts and cytotrophoblasts.
Cytogenetic and genome research 2006;114(3-4):302-11.
2006: Heinz-Ulrich G Weier; T B Tuton; Y Ito; Lisa W Chu; C-M Lu; Adolf Baumgartner; Horst Zitzelsberger; Jingly F Weier
Molecular cytogenetic characterization of chromosome 9-derived material in a human thyroid cancer cell line.
Cytogenetic and genome research 2006;114(3-4):284-91.
2006: Heinz-Ulrich G Weier; Lisa W Chu
Quantitative DNA fiber mapping in genome research and construction of physical maps.
Methods in molecular biology (Clifton, N.J.) 2006;338():31-57.
2005: Jingly F Weier; Heinz-Ulrich G Weier; Aida Nureddin; Roger A Pedersen; Catherine Racowsky
Aneuploidy involving chromosome 1 in failed-fertilized human oocytes is unrelated to maternal age.
Journal of assisted reproduction and genetics 2005;22(7-8):285-93.
2005: Adam M Breier; Heinz-Ulrich G Weier; Nicholas R Cozzarelli
Independence of replisomes in Escherichia coli chromosomal replication.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(11):3942-7.
2005: Jingly F Weier; Heinz-Ulrich G Weier; Christine J Jung; Matthew Gormley; Yan Zhou; Lisa W Chu; Olga Genbacev; Alexi A Wright; Susan J Fisher
Human cytotrophoblasts acquire aneuploidies as they differentiate to an invasive phenotype.
Developmental biology 2005;279(2):420-32.
2005: Heinz-Ulrich G Weier; Jingly F Weier; Maria Oter Renom; Xuezhong Zheng; Pere Colls; Aida Nureddin; Chau D Pham; Lisa W Chu; Catherine Racowsky; Santiago Munné
Fluorescence in situ hybridization and spectral imaging analysis of human oocytes and first polar bodies.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2005;53(3):269-72.
2005: Thomas Liehr; Heinz-Ulrich G Weier
14th workshop on fetal cells and fetal DNA.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2005;53(3):253-4.
2004: Heinz-Ulrich G Weier; Lisa W Chu; John P Murnane; Jingly F Weier
Applications and technical challenges of fluorescence in situ hybridization in stem cell research.
Blood cells, molecules & diseases 2004;32(1):68-76.
2002: Heinz-Ulrich G Weier; Karin M Greulich-Bode; Yuko Ito; Robert A Lersch; Jingly Fung
FISH in cancer diagnosis and prognostication: from cause to course of disease.
Expert review of molecular diagnostics 2002;2(2):109-19.
2002: Thomas Liehr; Anja Weise; Anita Heller; Heike Starke; Kristin Mrasek; Alma Kuechler; Heinz-Ulrich G Weier; Uwe Claussen
Multicolor chromosome banding (MCB) with YAC/BAC-based probes and region-specific microdissection DNA libraries.
Cytogenetic and genome research 2002;97(1-2):43-50.
2001: Heinz-Ulrich G Weier; Santiago Munné; Robert A Lersch; H Hsieh; Jan Smida; X Chen; julie R korenberg; Roger A Pedersen; Jingly Fung
Towards a full karyotype screening of interphase cells: 'FISH and chip' technology.
Molecular and cellular endocrinology 2001;183 Suppl 1():S41-5.
2001: HB Hsieh; Robert A Lersch; D E Callahan; S Hayward; M Wong; O H Clark; Heinz-Ulrich G Weier
Monitoring signal transduction in cancer: cDNA microarray for semiquantitative analysis.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2001;49(8):1057-8.
2001: Heinz-Ulrich G Weier
DNA fiber mapping techniques for the assembly of high-resolution physical maps.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2001;49(8):939-48.
2001: Robert A Lersch; Jingly Fung; HB Hsieh; Jan Smida; Heinz-Ulrich G Weier
Monitoring signal transduction in cancer: from chips to fish.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2001;49(7):925-6.
2001: Jingly Fung; Heinz-Ulrich G Weier; Roger A Pedersen
Detection of structural and numerical chromosome abnormalities in interphase cells using spectral imaging.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2001;49(6):797-8.
2001: Heinz-Ulrich G Weier; Horst Zitzelsberger; HB Hsieh; M V Sun; M Wong; Robert A Lersch; Paul Yaswen; Jan Smida; C Kuschnick; O H Clark
Monitoring signal transduction in cancer: tyrosine kinase gene expression profiling.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2001;49(5):673-4.
2001: Jingly Fung; S Munné; Heinz-Ulrich G Weier
Detection of chromosome translocation products in single interphase cell nuclei.
Methods in cell biology 2001;64():97-114.
2000: Jingly Fung; Heinz-Ulrich G Weier; James D Goldberg; Roger A Pedersen
Multilocus genetic analysis of single interphase cells by spectral imaging.
Human genetics 2000;107(6):615-22.
2000: S D Lin; P Cooper; Jingly Fung; Heinz-Ulrich G Weier; Edward M Rubin
Genome scan identifies a locus affecting gamma-globin level in human beta-cluster YAC transgenic mice.
Mammalian genome : official journal of the International Mammalian Genome Society 2000;11(11):1024-9.
2000: HB Hsieh; M Wang; Robert A Lersch; UJ Kim; Heinz-Ulrich G Weier
Rational design of landmark probes for quantitative DNA fiber mapping (QDFM).
Nucleic acids research 2000;28(8):E30.
2000: Robert A Lersch; Jingly Fung; Santiago Munné; Roger A Pedersen; Heinz-Ulrich G Weier
Case-specific, breakpoint-spanning DNA probes for analysis of single interphase cells.
Genetic testing 2000;4(3):273-8.
2000: Heinz-Ulrich G Weier; Cyril X George; Robert A Lersch; S Breitweser; J F Cheng; Charles E Samuel
Assignment of the RNA-specific adenosine deaminase gene (Adar) to mouse chromosome 3F2 by in situ hybridization.
Cytogenetics and cell genetics 2000;89(3-4):214-5.
1999: M C Gerling; G Jossart; Quan-Yang Duh; Heinz-Ulrich G Weier; Orlo H Clark; David M Young
Invasion of human follicular thyroid carcinoma cells in an in vivo invasion model.
Thyroid : official journal of the American Thyroid Association 1999;9(12):1221-6.
1999: Y Cao; HL Kang; X Xu; M Wang; S H Dho; Jun R Huh; B J Lee; Francis Kalush; D Bocskai; Y Ding; JG Tesmer; J Lee; E Moon; V Jurecic; Antonio Baldini; Heinz-Ulrich G Weier; Norman A Doggett; MI Simon; Mark D Adams; UJ Kim
A 12-Mb complete coverage BAC contig map in human chromosome 16p13.1-p11.2.
Genome research 1999;9(8):763-74.
1999: Heinz-Ulrich G Weier; Santiago Munné; Jingly Fung
Patient-specific probes for preimplantation genetic diagnosis of structural and numerical aberrations in interphase cells.
Journal of assisted reproduction and genetics 1999;16(4):182-91.
1999: Jingly Fung; S Munné; Jairo E Garcia; UJ Kim; Heinz-Ulrich G Weier
Molecular cloning of translocation breakpoints in a case of constitutional translocation t(11;22)(q23;q11) and preparation of probes for preimplantation genetic diagnosis.
Reproduction, fertility, and development 1999;11(1):17-23.
1999: Heinz-Ulrich G Weier; Jingly Fung; Robert A Lersch
Assignment of protooncogene MERTK (a.k.a. c-mer) to human chromosome 2q14.1 by in situ hybridization.
Cytogenetics and cell genetics 1999;84(1-2):91-2.
1998: Jennifer Fung; M M Moronne; Heinz-Ulrich G Weier
Simple blocking system for use with maleimide-labeled nucleic acid probes.
BioTechniques 1998;25(3):390-2, 394.
1998: Lars B Nielsen; D Kahn; Thomas Duell; Heinz-Ulrich G Weier; S Taylor; Stephen G Young
Apolipoprotein B gene expression in a series of human apolipoprotein B transgenic mice generated with recA-assisted restriction endonuclease cleavage-modified bacterial artificial chromosomes. An intestine-specific enhancer element is located between 54 and 62 kilobases 5' to the structural gene.
The Journal of biological chemistry 1998;273(34):21800-7.
1998: Santiago Munné; Jingly Fung; MJ Cassel; Carmen Márquez; Heinz-Ulrich G Weier
Preimplantation genetic analysis of translocations: case-specific probes for interphase cell analysis.
Human genetics 1998;102(6):663-74.
1998: Jingly Fung; William Hyun; PV Dandekar; Roger A Pedersen; Heinz-Ulrich G Weier
Spectral imaging in preconception/preimplantation genetic diagnosis of aneuploidy: multicolor, multichromosome screening of single cells.
Journal of assisted reproduction and genetics 1998;15(5):323-30.
1997: Thomas Duell; M Wang; J Wu; UJ Kim; Heinz-Ulrich G Weier
High-resolution physical map of the immunoglobulin lambda variant gene cluster assembled by quantitative DNA fiber mapping.
Genomics 1997;45(3):479-86.
1997: MJ Cassel; Santiago Munné; Jingly Fung; Heinz-Ulrich G Weier
Carrier-specific breakpoint-spanning DNA probes: an approach to preimplantation genetic diagnosis in interphase cells.
Human reproduction (Oxford, England) 1997;12(9):2019-27.
1997: Mark P Sawicki; E Arnold; SA Ebrahimi; Thomas Duell; S Jin; T Wood; Rita Chakrabarti; J Peters; Y Wan; GJ Samara; Heinz-Ulrich G Weier; Nitin Udar; E Passaro; Eri S Srivatsan
A transcript map encompassing the multiple endocrine neoplasia type-1 (MEN1) locus on chromosome 11q13.
Genomics 1997;42(3):405-12.
1997: Wendie A Robbins; Marvin L Meistrich; D Moore; Fredrick B Hagemeister; Heinz-Ulrich G Weier; MJ Cassel; G Wilson; Brenda Eskenazi; Andrew J Wyrobek
Chemotherapy induces transient sex chromosomal and autosomal aneuploidy in human sperm.
Nature genetics 1997;16(1):74-8.
1997: Desmond J Smith; M E Stevens; S P Sudanagunta; R T Bronson; M Makhinson; Ayako M Watabe; Thomas J O'Dell; Jingly Fung; Heinz-Ulrich G Weier; Jan-Fang Cheng; Edward M Rubin
Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome.
Nature genetics 1997;16(1):28-36.
1997: Thomas Duell; Lars B Nielsen; A Jones; Stephen G Young; Heinz-Ulrich G Weier
Construction of two near-kilobase resolution restriction maps of the 5' regulatory region of the human apolipoprotein B gene by quantitative DNA fiber mapping (QDFM).
Cytogenetics and cell genetics 1997;79(1-2):64-70.
1996: H Hessel; J Mittermüller; Horst Zitzelsberger; Heinz-Ulrich G Weier; M Bauchinger
Combined immunophenotyping and FISH with sex chromosome-specific DNA probes for the detection of chimerism in epidermal Langerhans cells after sex-mismatched bone marrow transplantation.
Histochemistry and cell biology 1996;106(5):481-5.
1996: G H Jossart; H D Epstein; J K Shaver; Heinz-Ulrich G Weier; K M Greulich; Serdar Tezelman; R F Grossman; Allan E Siperstein; Quan-Yang Duh; Orlo H Clark
Immunocytochemical detection of p53 in human thyroid carcinomas is associated with mutation and immortalization of cell lines.
The Journal of clinical endocrinology and metabolism 1996;81(10):3498-504.
1996: Horst Zitzelsberger; S Szücs; E Robens; Heinz-Ulrich G Weier; Heinz Höfler; M Bauchinger
Combined cytogenetic and molecular genetic analyses of fifty-nine untreated human prostate carcinomas.
Cancer genetics and cytogenetics 1996;90(1):37-44.
1996: Santiago Munné; Heinz-Ulrich G Weier
Simultaneous enumeration of chromosomes 13, 18, 21, X, and Y in interphase cells for preimplantation genetic diagnosis of aneuploidy.
Cytogenetics and cell genetics 1996;75(4):263-70.
1996: G H Jossart; B O'Brien; Jan-Fang Cheng; Q Tong; Sissy M Jhiang; Quan-Yang Duh; Orlo H Clark; Heinz-Ulrich G Weier
A novel multicolor hybridization scheme applied to localization of a transcribed sequence (D10S170/H4) and deletion mapping in the thyroid cancer cell line TPC-1.
Cytogenetics and cell genetics 1996;75(4):254-7.
1995: G H Jossart; K M Greulich; Allan E Siperstein; Quan-Yang Duh; Orlo H Clark; Heinz-Ulrich G Weier
Molecular and cytogenetic characterization of a t(1;10;21) translocation in the human papillary thyroid cancer cell line TPC-1 expressing the ret/H4 chimeric transcript.
Surgery 1995;118(6):1018-23.
1995: Heinz-Ulrich G Weier; C X George; K M Greulich; C E Samuel
The interferon-inducible, double-stranded RNA-specific adenosine deaminase gene (DSRAD) maps to human chromosome 1q21.1-21.2.
Genomics 1995;30(2):372-5.
1995: Heinz-Ulrich G Weier; M Wang; J C Mullikin; Y Zhu; Jan-Fang Cheng; K M Greulich; A Bensimon; Joe Gray
Quantitative DNA fiber mapping.
Human molecular genetics 1995;4(10):1903-10.
1995: Heinz-Ulrich G Weier; K M Greulich; David M Young
Dual temperature in situ hybridization.
BioTechniques 1995;19(3):364-6.
1995: Heinz-Ulrich G Weier; A P Rhein; F Shadravan; Colin Collins; Daniel Polikoff
Rapid physical mapping of the human trk protooncogene (NTRK1) to human chromosome 1q21-q22 by P1 clone selection, fluorescence in situ hybridization (FISH), and computer-assisted microscopy.
Genomics 1995;26(2):390-3.
1995: W A Robbins; Janet E Baulch; D Moore; Heinz-Ulrich G Weier; D Blakey; Andrew J Wyrobek
Three-probe fluorescence in situ hybridization to assess chromosome X, Y, and 8 aneuploidy in sperm of 14 men from two healthy groups: evidence for a paternal age effect on sperm aneuploidy.
Reproduction, fertility, and development 1995;7(4):799-809.
1994: Andrew J Wyrobek; W A Robbins; Y Mehraein; D Pinkel; Heinz-Ulrich G Weier
Detection of sex chromosomal aneuploidies X-X, Y-Y, and X-Y in human sperm using two-chromosome fluorescence in situ hybridization.
American journal of medical genetics 1994;53(1):1-7.
1994: Heinz-Ulrich G Weier; Daniel Polikoff; J J Fawcett; K M Greulich; K H Lee; S Cram; Verne M Chapman; Joe Gray
Generation of five high-complexity painting probe libraries from flow-sorted mouse chromosomes.
Genomics 1994;21(3):641-4.
1994: Horst Zitzelsberger; S Szücs; Heinz-Ulrich G Weier; L Lehmann; Herbert Braselmann; S Enders; A Schilling; J Breul; Heinz Höfler; M Bauchinger
Numerical abnormalities of chromosome 7 in human prostate cancer detected by fluorescence in situ hybridization (FISH) on paraffin-embedded tissue sections with centromere-specific DNA probes.
The Journal of pathology 1994;172(4):325-35.
1993: L C Yu; J Williams; B B Wang; M Vooijs; Heinz-Ulrich G Weier; M Sakamoto; K L Ying
Characterization of i(18p) in prenatal diagnosis by fluorescence in situ hybridization.
Prenatal diagnosis 1993;13(5):355-61.
1993: Heinz-Ulrich G Weier; B M Miller; L C Yu; J C Fuscoe
PCR cloning of a repeated DNA fragment from Chinese hamster ovary (CHO) cell X chromosomes and mapping by fluorescence in situ hybridization.
DNA sequence : the journal of DNA sequencing and mapping 1993;4(1):47-51.
1992: B M Miller; T Werner; Heinz-Ulrich G Weier; M Nüsse
Analysis of radiation-induced micronuclei by fluorescence in situ hybridization (FISH) simultaneously using telomeric and centromeric DNA probes.
Radiation research 1992;131(2):177-85.
1992: JN Lucas; AA Awa; T Straume; M Poggensee; Y Kodama; M Nakano; K Ohtaki; Heinz-Ulrich G Weier; Daniel Pinkel; Joe Gray
Rapid translocation frequency analysis in humans decades after exposure to ionizing radiation.
International journal of radiation biology 1992;62(1):53-63.
1992: Heinz-Ulrich G Weier; Joe Gray
A degenerate alpha satellite probe, detecting a centromeric deletion on chromosome 21 in an apparently normal human male, shows limitations of the use of satellite DNA probes for interphase ploidy analysis.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology 1992;4(2):81-6.
1992: Heinz-Ulrich G Weier; Horst Zitzelsberger; Joe Gray
Differential staining of human and murine chromatin in situ by hybridization with species-specific satellite DNA probes.
Biochemical and biophysical research communications 1992;182(3):1313-9.
1991: Heinz-Ulrich G Weier; H D Kleine; Joe Gray
Labeling of the centromeric region on human chromosome 8 by in situ hybridization.
Human genetics 1991;87(4):489-94.
1991: Heinz-Ulrich G Weier; JN Lucas; M Poggensee; R Segraves; Daniel Pinkel; Joe Gray
Two-color hybridization with high complexity chromosome-specific probes and a degenerate alpha satellite probe DNA allows unambiguous discrimination between symmetrical and asymmetrical translocations.
Chromosoma 1991;100(6):371-6.
1991: B M Miller; Horst Zitzelsberger; Heinz-Ulrich G Weier; Ilse-Dore Adler
Classification of micronuclei in murine erythrocytes: immunofluorescent staining using CREST antibodies compared to in situ hybridization with biotinylated gamma satellite DNA.
Mutagenesis 1991;6(4):297-302.
1991: Heinz-Ulrich G Weier; Horst Zitzelsberger; Joe Gray
Non-isotopical labeling of murine heterochromatin in situ by hybridization with in vitro-synthesized biotinylated gamma (major) satellite DNA.
BioTechniques 1991;10(4):498-502, 504-5.
1991: Joe Gray; J Lucas; Olli Kallioniemi; Anne Kallioniemi; Wen-Lin Kuo; T Straume; D Tkachuk; T Tenjin; Heinz-Ulrich G Weier; Daniel Pinkel
Applications of fluorescence in situ hybridization in biological dosimetry and detection of disease-specific chromosome aberrations.
Progress in clinical and biological research 1991;372():399-411.
1990: Heinz-Ulrich G Weier; R Segraves; Daniel Pinkel; Joe Gray
Synthesis of Y chromosome-specific labeled DNA probes by in vitro DNA amplification.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1990;38(3):421-6.
1990: Heinz-Ulrich G Weier; C Rosette
Generation of clonal DNA templates for in vitro transcription without plasmid purification.
BioTechniques 1990;8(3):252-7.
1988: Heinz-Ulrich G Weier; C Rosette
Generation of labeled RNA probes from enzymatically amplified DNA templates.
Nucleic acids research 1988;16(24):11836.