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Lev Weiner

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Protein Folding

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TOP 3
Eugene Khaskin; Gregory Leitus; Yael Diskin-Posner; Lev Weiner; David Milstein
Formal loss of an H radical by a cobalt complex via metal-ligand cooperation.
Israel Silman; Joel L Sussman; Mathilde M Triquigneaux; Yacov Ashani; Leesa J Deterding; Marilyn Ehrenshaft; Ronald P Mason; Aviv Paz; Esther Roth; Valery L Shnyrov; Yechun Xu; Lev Weiner
The specific interaction of the photosensitizer methylene blue with acetylcholinesterase provides a model system for studying the molecular consequences of photodynamic therapy.
Aviv Paz; Esther Roth; Valery L Shnyrov; Israel Silman; Joel L Sussman; Yacov Ashani; Yechun Xu; Lev Weiner
Structural and functional characterization of the interaction of the photosensitizing probe methylene blue with Torpedo californica acetylcholinesterase.

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All Publications

2013: Eugene Khaskin; Gregory Leitus; Yael Diskin-Posner; Lev Weiner; David Milstein
Formal loss of an H radical by a cobalt complex via metal-ligand cooperation.
Chemical communications (Cambridge, England) 2013;49(27):2771-3.
2013: Israel Silman; Joel L Sussman; Mathilde M Triquigneaux; Yacov Ashani; Leesa J Deterding; Marilyn Ehrenshaft; Ronald P Mason; Aviv Paz; Esther Roth; Valery L Shnyrov; Yechun Xu; Lev Weiner
The specific interaction of the photosensitizer methylene blue with acetylcholinesterase provides a model system for studying the molecular consequences of photodynamic therapy.
Chemico-biological interactions 2013;203(1):63-6.
2012: Aviv Paz; Esther Roth; Valery L Shnyrov; Israel Silman; Joel L Sussman; Yacov Ashani; Yechun Xu; Lev Weiner
Structural and functional characterization of the interaction of the photosensitizing probe methylene blue with Torpedo californica acetylcholinesterase.
Protein science : a publication of the Protein Society 2012;21(8):1138-52.
2011: Lev Weiner; Esther Roth; Israel Silman
Targeted oxidation of Torpedo californica acetylcholinesterase by singlet oxygen.
Photochemistry and photobiology 2011;87(2):308-16.
2011: Jessica Ettedgui; Yael Diskin-Posner; Lev Weiner; Ronny Neumann
Photoreduction of carbon dioxide to carbon monoxide with hydrogen catalyzed by a rhenium(I) phenanthroline-polyoxometalate hybrid complex.
Journal of the American Chemical Society 2011;133(2):188-90.
2010: Joanna Grzyb; Fei Xu; Lev Weiner; Eduard J Reijerse; Wolfgang Lubitz; Vikas Nanda; Dror Noy
De novo design of a non-natural fold for an iron-sulfur protein: alpha-helical coiled-coil with a four-iron four-sulfur cluster binding site in its central core.
Biochimica et biophysica acta 2010;1797(3):406-13.
2010: Alexander M Khenkin; Irena Efremenko; Lev Weiner; Jan M L Martin; Ronny Neumann
Photochemical reduction of carbon dioxide catalyzed by a ruthenium-substituted polyoxometalate.
Chemistry (Weinheim an der Bergstrasse, Germany) 2010;16(4):1356-64.
2009: Stephan W Kohl; Lev Weiner; Leonid Schwartsburd; Leonid Konstantinovski; Linda J W Shimon; Yehoshoa Ben-David; Mark A Iron; David Milstein
Consecutive thermal H2 and light-induced O2 evolution from water promoted by a metal complex.
Science (New York, N.Y.) 2009;324(5923):74-7.
2009: Lev Weiner; Irina Shin; Linda J W Shimon; Talia Miron; Meir Wilchek; David Mirelman; Felix Frolow; Aharon Rabinkov
Thiol-disulfide organization in alliin lyase (alliinase) from garlic (Allium sativum).
Protein science : a publication of the Protein Society 2009;18(1):196-205.
2008: Aviv Paz; Tzviya Zeev-Ben-Mordehai; Martin Lundqvist; Eilon Sherman; Efstratios Mylonas; Lev Weiner; Gilad Haran; Dmitri I Svergun; Frans A A Mulder; Joel Sussman; Israel Silman
Biophysical characterization of the unstructured cytoplasmic domain of the human neuronal adhesion protein neuroligin 3.
Biophysical journal 2008;95(4):1928-44.
2008: Vered Lev-Goldman; Brenda Mester; Nurit Ben-Aroya; Tamar Hanoch; Barbara Rupp; Tsvetanka Stanoeva; Georg Gescheidt; Rony Seger; Yitzhak Koch; Lev Weiner; Mati Fridkin
Conjugates of gonadotropin releasing hormone (GnRH) with carminic acid: Synthesis, generation of reactive oxygen species (ROS) and biological evaluation.
Bioorganic & medicinal chemistry 2008;16(14):6789-98.
2007: Moran Feller; Eyal Ben-Ari; Tarkeshwar Gupta; Linda J W Shimon; Gregory Leitus; Yael Diskin-Posner; Lev Weiner; David Milstein
Mononuclear Rh(II) PNP-type complexes. Structure and reactivity.
Inorganic chemistry 2007;46(25):10479-90.
2007: Gad Lavie; Tilda Barliya; Mathilda Mandel; Michael Blank; Yonina Ron Kella; Arie Orenstein; Tami Livnat; Noga Friedman; Lev Weiner; Mordechai Sheves; Dov Weinberger
"Competitive quenching": a mechanism by which perihydroxylated perylenequinone photosensitizers can prevent adverse phototoxic damage caused by verteporfin during photodynamic therapy.
Photochemistry and photobiology 2007;83(5):1270-7.
2006: Vered Lev-Goldman; Brenda Mester; Nurit Ben-Aroya; Yitzhak Koch; Lev Weiner; Mati Fridkin
Synthesis and active oxygen generation by new emodin derivatives and their gonadotropin-releasing hormone conjugates.
Bioconjugate chemistry 2006;17(4):1008-16.
2006: Christian M Frech; Yehoshoa Ben-David; Lev Weiner; David Milstein
Metal-controlled reactivity of a pincer-type, sigma-coordinated naphthyl radical anion.
Journal of the American Chemical Society 2006;128(22):7128-9.
2006: Keren Mevorat-Kaplan; Lev Weiner; Mordechai Sheves
Spin labeling of Natronomonas pharaonis halorhodopsin: probing the cysteine residues environment.
The journal of physical chemistry. B 2006;110(17):8825-31.
2005: Alexander M Khenkin; Lev Weiner; Ronny Neumann
Selective ortho hydroxylation of nitrobenzene with molecular oxygen catalyzed by the H5PV2Mo10O40 polyoxometalate.
Journal of the American Chemical Society 2005;127(28):9988-9.
2005: Itsik Bar-Nahum; Kuppala V Narasimhulu; Lev Weiner; Ronny Neumann
Phenanthroline-polyoxometalate hybrid compounds and the observation of intramolecular charge transfer.
Inorganic chemistry 2005;44(14):4900-2.
2005: Yahel Vakrat-Haglili; Lev Weiner; Vlad Brumfeld; Alexander Brandis; Yoram Salomon; Brian McLlroy; Brian C Wilson; Anna Pawlak; Malgorzata Rozanowska; Tadeusz Sarna; Avigdor Scherz
The microenvironment effect on the generation of reactive oxygen species by Pd-bacteriopheophorbide.
Journal of the American Chemical Society 2005;127(17):6487-97.
2005: Shai Rahimipour; Naomi Litichever-Coslovsky; Moran Alaluf; Dalia Freeman; Benjamin Ehrenberg; Lev Weiner; Yehuda Mazur; Mati Fridkin; Yitzhak Koch
Novel methyl helianthrones as photosensitizers: synthesis and biological evaluation.
Photochemistry and photobiology 2005;81(2):250-8.
2005: AYELET GONEN; Dror Harats; Aharon Rabinkov; Talia Miron; David Mirelman; Meir Wilchek; Lev Weiner; Esfir Ulman; Hana Levkovitz; Dikla Ben shushan; Aviv Shaish
The antiatherogenic effect of allicin: possible mode of action.
Pathobiology : journal of immunopathology, molecular and cellular biology 2005;72(6):325-34.
2004: Ephraim Yavin; Eric D A Stemp; Lev Weiner; Irit Sagi; Rina Arad-Yellin; Abraham Shanzer
Direct photo-induced DNA strand scission by a ruthenium bipyridyl complex.
Journal of inorganic biochemistry 2004;98(11):1750-6.
2003: Charles B Millard; Valery L Shnyrov; Simon Newstead; Irina Shin; Esther Roth; Israel Silman; Lev Weiner
Stabilization of a metastable state of Torpedo californica acetylcholinesterase by chemical chaperones.
Protein science : a publication of the Protein Society 2003;12(10):2337-47.
2003: Shai Rahimipour; Cornelia Palivan; Frédérique Barbosa; Itzhak Bilkis; Yitzhak Koch; Lev Weiner; Mati Fridkin; Yehuda Mazur; Georg Gescheidt
Chemical and photochemical electron transfer of new helianthrone derivatives: aspects of their photodynamic activity.
Journal of the American Chemical Society 2003;125(5):1376-84.
2002: Irina Shin; Ellen Wachtel; Esther Roth; C Bon; Israel Silman; Lev Weiner
Thermal denaturation of Bungarus fasciatus acetylcholinesterase: Is aggregation a driving force in protein unfolding?
Protein science : a publication of the Protein Society 2002;11(8):2022-32.
2002: Talia Miron; Irina Shin; Guy Feigenblat; Lev Weiner; David Mirelman; Meir Wilchek; Aharon Rabinkov
A spectrophotometric assay for allicin, alliin, and alliinase (alliin lyase) with a chromogenic thiol: reaction of 4-mercaptopyridine with thiosulfinates.
Analytical biochemistry 2002;307(1):76-83.
2002: Revital Ben-Daniel; Lev Weiner; Ronny Neumann
Activation of nitrous oxide and selective epoxidation of alkenes catalyzed by the manganese-substituted polyoxometalate, [Mn(III)2ZnW(Zn2W9O34)2]10-.
Journal of the American Chemical Society 2002;124(30):8788-9.
2001: Alexander M Khenkin; Lev Weiner; Y Wang; Ronny Neumann
Electron and oxygen transfer in polyoxometalate, H(5)PV(2)Mo(10)O(40), catalyzed oxidation of aromatic and alkyl aromatic compounds: evidence for aerobic Mars-van Krevelen-type reactions in the liquid homogeneous phase.
Journal of the American Chemical Society 2001;123(35):8531-42.
2001: Shai Rahimipour; Itzhak Bilkis; V Péron; Georg Gescheidt; Frédérique Barbosa; Yehuda Mazur; Yitzhak Koch; Lev Weiner; Mati Fridkin
Generation of free radicals by emodic acid and its [D-Lys6]GnRH-conjugate.
Photochemistry and photobiology 2001;74(2):226-36.
2001: Shai Rahimipour; Cornelia Palivan; Dalia Freeman; Frédérique Barbosa; Mati Fridkin; Lev Weiner; Yehuda Mazur; Georg Gescheidt
Hypericin derivatives: substituent effects on radical-anion formation.
Photochemistry and photobiology 2001;74(2):149-56.
2001: T Eliash; Lev Weiner; Michael Ottolenghi; Mordechai Sheves
Specific binding sites for cations in bacteriorhodopsin.
Biophysical journal 2001;81(2):1155-62.
2001: Asaph Aharoni; Lev Weiner; Aaron Lewis; Michael Ottolenghi; Mordechai Sheves
Nonisomerizable non-retinal chromophores initiate light-induced conformational alterations in bacterioopsin.
Journal of the American Chemical Society 2001;123(27):6612-6.
2001: Pnina Green; Sabina Glozman; Lev Weiner; Ephraim Yavin
Enhanced free radical scavenging and decreased lipid peroxidation in the rat fetal brain after treatment with ethyl docosahexaenoate.
Biochimica et biophysica acta 2001;1532(3):203-12.
2000: Aharon Rabinkov; Talia Miron; David Mirelman; Meir Wilchek; Sabina Glozman; Ephraim Yavin; Lev Weiner
S-Allylmercaptoglutathione: the reaction product of allicin with glutathione possesses SH-modifying and antioxidant properties.
Biochimica et biophysica acta 2000;1499(1-2):144-153.
2000: Asaph Aharoni; Lev Weiner; Michael Ottolenghi; Mordechai Sheves
Bacteriorhodpsin experiences light-induced conformational alterations in nonisomerizable C(13)=C(14) pigments. A study with EPR.
The Journal of biological chemistry 2000;275(28):21010-6.
2000: Talia Miron; Aharon Rabinkov; David Mirelman; Meir Wilchek; Lev Weiner
The mode of action of allicin: its ready permeability through phospholipid membranes may contribute to its biological activity.
Biochimica et biophysica acta 2000;1463(1):20-30.
1999: Lev Weiner; Esther Roth; Yehuda Mazur; Israel Silman
Targeted cross-linking of a molten globule form of acetylcholinesterase by the virucidal agent hypericin.
Biochemistry 1999;38(35):11401-5.
1999: Sabina Glozman; Pnina Green; B Kamensky; Lev Weiner; Ephraim Yavin
Ethyl docosahexaenoic acid administration during intrauterine life enhances prostanoid production and reduces free radicals generation in the fetal rat brain.
Lipids 1999;34 Suppl():S247-8.
1998: Talia Miron; Aharon Rabinkov; David Mirelman; Lev Weiner; Meir Wilchek
A spectrophotometric assay for allicin and alliinase (Alliin lyase) activity: reaction of 2-nitro-5-thiobenzoate with thiosulfinates.
Analytical biochemistry 1998;265(2):317-25.
1998: Irina Shin; Israel Silman; C Bon; Lev Weiner
Liposome-catalyzed unfolding of acetylcholinesterase from Bungarus fasciatus.
Biochemistry 1998;37(13):4310-6.
1998: Aharon Rabinkov; Talia Miron; Leonid Konstantinovski; Meir Wilchek; David Mirelman; Lev Weiner
The mode of action of allicin: trapping of radicals and interaction with thiol containing proteins.
Biochimica et biophysica acta 1998;1379(2):233-44.
1997: M Peled-Kamar; Joseph Lotem; I Wirguin; Lev Weiner; A Hermalin; Yoram Groner
Oxidative stress mediates impairment of muscle function in transgenic mice with elevated level of wild-type Cu/Zn superoxide dismutase.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):3883-7.
1997: Irina Shin; D Kreimer; Israel Silman; Lev Weiner
Membrane-promoted unfolding of acetylcholinesterase: a possible mechanism for insertion into the lipid bilayer.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(7):2848-52.
1996: D I Kreimer; Irina Shin; V L Shnyrov; E Villar; Israel Silman; Lev Weiner
Two partially unfolded states of Torpedo californica acetylcholinesterase.
Protein science : a publication of the Protein Society 1996;5(9):1852-64.
1995: D I Kreimer; V L Shnyrov; E Villar; Israel Silman; Lev Weiner
Irreversible thermal denaturation of Torpedo californica acetylcholinesterase.
Protein science : a publication of the Protein Society 1995;4(11):2349-57.
1994: D I Kreimer; R Szosenfogel; Daniella Goldfarb; Israel Silman; Lev Weiner
Two-state transition between molten globule and unfolded states of acetylcholinesterase as monitored by electron paramagnetic resonance spectroscopy.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(25):12145-9.
1994: D I Kreimer; E A Dolginova; Maria L Raves; Joel Sussman; Israel Silman; Lev Weiner
A metastable state of Torpedo californica acetylcholinesterase generated by modification with organomercurials.
Biochemistry 1994;33(48):14407-18.
1994: J Eichler; D I Kreimer; L Varon; Israel Silman; Lev Weiner
A "molten globule" of Torpedo acetylcholinesterase undergoes thiol-disulfide exchange.
The Journal of biological chemistry 1994;269(48):30093-6.
1994: Lev Weiner; D Kreimer; E Roth; Israel Silman
Oxidative stress transforms acetylcholinesterase to a molten-globule-like state.
Biochemical and biophysical research communications 1994;198(3):915-22.