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Birgit Weinhold

Research Profile

Living Beings

Chemicals & Drugs

Physiology

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Protein Structure, Tertiary

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Amino Acid Sequences

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Birgit Weinhold; Kirstin Worthmann; Brigitte Philippens; Wiebke Schaper; Mario Schiffer; Melanie Sellmeier; Ulrike Bernard; Linda Blume; Sebastian P Galuska; Rita Gerardy-Schahn; Hildegard Geyer; Rudolf Geyer; Stephanie Groos; Elina Kats; Anja K Münster-Kühnel
Deficits in sialylation impair podocyte maturation.
Wiebke Schaper; Joe Tiralongo; Jana Ustinova; Birgit Weinhold; Martin Bastmeyer; J Bentrop; Linda Blume; Elina Kats; Anja K Münster-Kühnel
Identification and biochemical characterization of two functional CMP-sialic acid synthetases in Danio rerio.
Miriam Schiff; Iris Röckle; Hannelore Burkhardt; Birgit Weinhold; Herbert Hildebrandt
Thalamocortical pathfinding defects precede degeneration of the reticular thalamic nucleus in polysialic acid-deficient mice.

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All Publications

2012: Birgit Weinhold; Kirstin Worthmann; Brigitte Philippens; Wiebke Schaper; Mario Schiffer; Melanie Sellmeier; Ulrike Bernard; Linda Blume; Sebastian P Galuska; Rita Gerardy-Schahn; Hildegard Geyer; Rudolf Geyer; Stephanie Groos; Elina Kats; Anja K Münster-Kühnel
Deficits in sialylation impair podocyte maturation.
Journal of the American Society of Nephrology : JASN 2012;23(8):1319-28.
2012: Wiebke Schaper; Joe Tiralongo; Jana Ustinova; Birgit Weinhold; Martin Bastmeyer; J Bentrop; Linda Blume; Elina Kats; Anja K Münster-Kühnel
Identification and biochemical characterization of two functional CMP-sialic acid synthetases in Danio rerio.
The Journal of biological chemistry 2012;287(16):13239-48.
2011: Miriam Schiff; Iris Röckle; Hannelore Burkhardt; Birgit Weinhold; Herbert Hildebrandt
Thalamocortical pathfinding defects precede degeneration of the reticular thalamic nucleus in polysialic acid-deficient mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(4):1302-12.
2010: Sebastian P Galuska; Manuela Rollenhagen; Moritz Kaup; Katinka Eggers; Imke Oltmann-Norden; Miriam Schiff; Maike Hartmann; Birgit Weinhold; Herbert Hildebrandt; Rudolf Geyer; Martina Mühlenhoff; Hildegard Geyer
Synaptic cell adhesion molecule SynCAM 1 is a target for polysialylation in postnatal mouse brain.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(22):10250-5.
2010: Sebastian P Galuska; Hildegard Geyer; Birgit Weinhold; Maria Kontou; René C Röhrich; Ulrike Bernard; Rita Gerardy-Schahn; Werner Reutter; Anja Münster-Kühnel; Rudolf Geyer
Quantification of nucleotide-activated sialic acids by a combination of reduction and fluorescent labeling.
Analytical chemistry 2010;82(11):4591-8.
2009: Melanie Oschlies; Achim Dickmanns; Thomas Haselhorst; Wiebke Schaper; Katharina Stummeyer; Joe Tiralongo; Birgit Weinhold; Rita Gerardy-Schahn; Mark von Itzstein; Ralf Ficner; Anja K Münster-Kühnel
A C-terminal phosphatase module conserved in vertebrate CMP-sialic acid synthetases provides a tetramerization interface for the physiologically active enzyme.
Journal of molecular biology 2009;393(1):83-97.
2009: Herbert Hildebrandt; Martina Mühlenhoff; Imke Oltmann-Norden; Iris Röckle; Hannelore Burkhardt; Birgit Weinhold; Rita Gerardy-Schahn
Imbalance of neural cell adhesion molecule and polysialyltransferase alleles causes defective brain connectivity.
Brain : a journal of neurology 2009;132(Pt 10):2831-8.
2009: Miriam Schiff; Birgit Weinhold; Claudia Grothe; Herbert Hildebrandt
NCAM and polysialyltransferase profiles match dopaminergic marker gene expression but polysialic acid is dispensable for development of the midbrain dopamine system.
Journal of neurochemistry 2009;110(5):1661-73.
2009: Martina Mühlenhoff; Imke Oltmann-Norden; Birgit Weinhold; Herbert Hildebrandt; Rita Gerardy-Schahn
Brain development needs sugar: the role of polysialic acid in controlling NCAM functions.
Biological chemistry 2009;390(7):567-74.
2009: Julia Jungnickel; Christian Brämer; Paul Bronzlik; Esther Lipokatic-Takacs; Birgit Weinhold; Rita Gerardy-Schahn; Claudia Grothe
Level and localization of polysialic acid is critical for early peripheral nerve regeneration.
Molecular and cellular neurosciences 2009;40(3):374-81.
2008: Iris Röckle; Ralph Seidenfaden; Birgit Weinhold; Martina Mühlenhoff; Rita Gerardy-Schahn; Herbert Hildebrandt
Polysialic acid controls NCAM-induced differentiation of neuronal precursors into calretinin-positive olfactory bulb interneurons.
Developmental neurobiology 2008;68(9):1170-84.
2007: Herbert Hildebrandt; Martina Mühlenhoff; Birgit Weinhold; Rita Gerardy-Schahn
Dissecting polysialic acid and NCAM functions in brain development.
Journal of neurochemistry 2007;103 Suppl 1():56-64.
2006: Sebastian P Galuska; Imke Oltmann-Norden; Hildegard Geyer; Birgit Weinhold; Klaus Kuchelmeister; Herbert Hildebrandt; Rita Gerardy-Schahn; Rudolf Geyer; Martina Mühlenhoff
Polysialic acid profiles of mice expressing variant allelic combinations of the polysialyltransferases ST8SiaII and ST8SiaIV.
The Journal of biological chemistry 2006;281(42):31605-15.
2006: Oleg Senkov; Mu Sun; Birgit Weinhold; Rita Gerardy-Schahn; Melitta Schachner; Alexander Dityatev
Polysialylated neural cell adhesion molecule is involved in induction of long-term potentiation and memory acquisition and consolidation in a fear-conditioning paradigm.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(42):10888-109898.
2006: Luminita Stoenica; Oleg Senkov; Rita Gerardy-Schahn; Birgit Weinhold; Melitta Schachner; Alexander Dityatev
In vivo synaptic plasticity in the dentate gyrus of mice deficient in the neural cell adhesion molecule NCAM or its polysialic acid.
The European journal of neuroscience 2006;23(9):2255-64.
2005: Birgit Weinhold; Ralph Seidenfaden; Iris Röckle; Martina Mühlenhoff; Frank Schertzinger; Sidonie Conzelmann; Jamey D Marth; Rita Gerardy-Schahn; Herbert Hildebrandt
Genetic ablation of polysialic acid causes severe neurodevelopmental defects rescued by deletion of the neural cell adhesion molecule.
The Journal of biological chemistry 2005;280(52):42971-7.
2004: Anja K Münster-Kühnel; Joe Tiralongo; Stephan Krapp; Birgit Weinhold; Valentina Ritz-Sedlacek; Uwe Jacob; Rita Gerardy-Schahn
Structure and function of vertebrate CMP-sialic acid synthetases.
Glycobiology 2004;14(10):43R-51R.
2002: Anja-K Munster; Birgit Weinhold; Birgit Gotza; Martina Muhlenhoff; Matthias Frosch; Rita Gerardy-Schahn
Nuclear localization signal of murine CMP-Neu5Ac synthetase includes residues required for both nuclear targeting and enzymatic activity.
The Journal of biological chemistry 2002;277(22):19688-96.
2001: Gerhard Schratt; Birgit Weinhold; A S Lundberg; S Schuck; Jürgen Berger; Heinz Schwarz; Robert A. Weinberg; Ulrich Rüther; Alfred Nordheim
Serum response factor is required for immediate-early gene activation yet is dispensable for proliferation of embryonic stem cells.
Molecular and cellular biology 2001;21(8):2933-43.
2000: Birgit Weinhold; Gerhard Schratt; Sergei Arsenian; Jürgen Berger; K Kamino; Heinz Schwarz; Ulrich Rüther; Alfred Nordheim
Srf(-/-) ES cells display non-cell-autonomous impairment in mesodermal differentiation.
The EMBO journal 2000;19(21):5835-44.
1998: Sergei Arsenian; Birgit Weinhold; M Oelgeschläger; Ulrich Rüther; Alfred Nordheim
Serum response factor is essential for mesoderm formation during mouse embryogenesis.
The EMBO journal 1998;17(21):6289-99.
1997: Birgit Weinhold; Ulrich Rüther
Interleukin-6-dependent and -independent regulation of the human C-reactive protein gene.
The Biochemical journal 1997;327 ( Pt 2)():425-9.
1997: Birgit Weinhold; Augustinus Bader; V Poli; Ulrich Rüther
Interleukin-6 is necessary, but not sufficient, for induction of the humanC-reactive protein gene in vivo.
The Biochemical journal 1997;325 ( Pt 3)():617-21.
1997: Frank Eitner; R Westerhuis; Michael Burg; Birgit Weinhold; Hermann-Josef Gröne; Tammo Ostendorf; Ulrich Rüther; Karl-Martin Koch; A J Rees; Jürgen Floege
Role of interleukin-6 in mediating mesangial cell proliferation and matrix production in vivo.
Kidney international 1997;51(1):69-78.