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Elmar Weinhold

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Migle Tomkuviene; Elmar Weinhold; Ignas Cerniauskas; Béatrice Clouet-d'Orval; Saulius Klimasauskas
Programmable sequence-specific click-labeling of RNA using archaeal box C/D RNP methyltransferases.
Sophie Willnow; Bernhard Lüscher; Michael Martin; Elmar Weinhold
A selenium-based click AdoMet analogue for versatile substrate labeling with wild-type protein methyltransferases.
Soohong Kim; Ron R Lin; Elmar Weinhold; Shimon Weiss; Sangyoon Chung; Ryan A Colyer; Thomas Dertinger; Anna Gottfried; Andrew S Kim; Yuval Ebenstein
Enzymatically incorporated genomic tags for optical mapping of DNA-binding proteins.

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2012: Migle Tomkuviene; Elmar Weinhold; Ignas Cerniauskas; Béatrice Clouet-d'Orval; Saulius Klimasauskas
Programmable sequence-specific click-labeling of RNA using archaeal box C/D RNP methyltransferases.
Nucleic acids research 2012;40(14):6765-73.
2012: Sophie Willnow; Bernhard Lüscher; Michael Martin; Elmar Weinhold
A selenium-based click AdoMet analogue for versatile substrate labeling with wild-type protein methyltransferases.
Chembiochem : a European journal of chemical biology 2012;13(8):1167-73.
2012: Soohong Kim; Ron R Lin; Elmar Weinhold; Shimon Weiss; Sangyoon Chung; Ryan A Colyer; Thomas Dertinger; Anna Gottfried; Andrew S Kim; Yuval Ebenstein
Enzymatically incorporated genomic tags for optical mapping of DNA-binding proteins.
Angewandte Chemie (International ed. in English) 2012;51(15):3578-81.
2012: Thomas Lenz; Peter Poot; Elmar Weinhold; Mathias Dreger
Profiling of methyltransferases and other S-Adenosyl-L-homocysteine-binding proteins by Capture Compound mass spectrometry.
Methods in molecular biology (Clifton, N.J.) 2012;803():97-125.
2011: Anna Gottfried; Elmar Weinhold
Sequence-specific covalent labelling of DNA.
Biochemical Society transactions 2011;39(2):623-8.
2010: Wibke Peters; Sophie Willnow; Mike Duisken; Henning Kleine; Thomas Macherey; Kelly E Duncan; David W Litchfield; Bernhard Lüscher; Elmar Weinhold
Enzymatic site-specific functionalization of protein methyltransferase substrates with alkynes for click labeling.
Angewandte Chemie (International ed. in English) 2010;49(30):5170-3.
2010: Christian Dalhoff; Michael Hüben; Thomas Lenz; Peter Poot; Eckhard Nordhoff; Hubert Köster; Elmar Weinhold
Synthesis of S-adenosyl-L-homocysteine capture compounds for selective photoinduced isolation of methyltransferases.
Chembiochem : a European journal of chemical biology 2010;11(2):256-65.
2008: Matthias Bahr; Valérie Gabelica; Anton Granzhan; Marie-Paule Teulade-Fichou; Elmar Weinhold
Selective recognition of pyrimidine-pyrimidine DNA mismatches by distance-constrained macrocyclic bis-intercalators.
Nucleic acids research 2008;36(15):5000-12.
2008: Rudolf Repges; Christine Beuck; Elmar Weinhold; Gerhard Raabe; Jörg Fleischhauer
6-Thioguanine in DNA as CD-spectroscopic probe to study local structural changes upon protein binding.
Chirality 2008;20(9):978-84.
2008: Stephanie Wilkinson; Michael Diechtierow; R August Estabrook; Falk Schmidt; Michael Hüben; Elmar Weinhold; Norbert O Reich
Molecular scale architecture: engineered three- and four-way junctions.
Bioconjugate chemistry 2008;19(2):470-5.
2008: Matthias Bahr; Valerie Gabélica; Anton Granzhan; Elmar Weinhold; Marie-Paule Teulade-Fichou
Recognition of homopyrimidine mismatches by distance-constrained macrocyclic bisintercalators.
Nucleic acids symposium series (2004) 2008;(52):109-10.
2008: Falk H-G Schmidt; Michael Hüben; Basar Gider; Francois Renault-Mihara; Marie-Paule Teulade-Fichou; Elmar Weinhold
Sequence-specific Methyltransferase-Induced Labelling (SMILing) of plasmid DNA for studying cell transfection.
Bioorganic & medicinal chemistry 2008;16(1):40-8.
2007: Goran Pljevaljcić; Falk Schmidt; Axel J Scheidig; Rudi Lurz; Elmar Weinhold
Quantitative labeling of long plasmid DNA with nanometer precision.
Chembiochem : a European journal of chemical biology 2007;8(13):1516-9.
2007: Thomas Lenz; Eleanor Y M Bonnist; Goran Pljevaljcić; Robert K Neely; David T F Dryden; Axel J Scheidig; Anita C Jones; Elmar Weinhold
2-Aminopurine flipped into the active site of the adenine-specific DNA methyltransferase M.TaqI: crystal structures and time-resolved fluorescence.
Journal of the American Chemical Society 2007;129(19):6240-8.
2007: Grazvydas Lukinavicius; Vidmantas Lapiene; Zdislav Stasevskij; Christian Dalhoff; Elmar Weinhold; Saulius Klimasauskas
Targeted labeling of DNA by methyltransferase-directed transfer of activated groups (mTAG).
Journal of the American Chemical Society 2007;129(10):2758-9.
2007: Saulius Klimasauskas; Elmar Weinhold
A new tool for biotechnology: AdoMet-dependent methyltransferases.
Trends in biotechnology 2007;25(3):99-104.
2007: Matthias Bahr; Linda Valis; Hans-Achim Wagenknecht; Elmar Weinhold
DNA labelling topologies for monitoring DNA-protein complex formation by fluorescence anisotropy.
Nucleosides, nucleotides & nucleic acids 2007;26(10-12):1581-4.
2006: Christian Dalhoff; Grazvydas Lukinavicius; Saulius Klimasauskas; Elmar Weinhold
Synthesis of S-adenosyl-L-methionine analogs and their use for sequence-specific transalkylation of DNA by methyltransferases.
Nature protocols 2006;1(4):1879-86.
2006: Christian Dalhoff; Grazvydas Lukinavicius; Saulius Klimasăuskas; Elmar Weinhold
Direct transfer of extended groups from synthetic cofactors by DNA methyltransferases.
Nature chemical biology 2006;2(1):31-2.
2004: Goran Pljevaljcić; Falk Schmidt; Elmar Weinhold
Sequence-specific methyltransferase-induced labeling of DNA (SMILing DNA).
Chembiochem : a European journal of chemical biology 2004;5(3):265-9.
2004: Goran Pljevaljcic; Falk Schmidt; Alexander Peschlow; Elmar Weinhold
Sequence-specific DNA labeling using methyltransferases.
Methods in molecular biology (Clifton, N.J.) 2004;283():145-61.
2003: Arnaud David; Nathalie Bleimling; Christine Beuck; Jean-Marie Lehn; Elmar Weinhold; Marie-Paule Teulade-Fichou
DNA mismatch-specific base flipping by a bisacridine macrocycle.
Chembiochem : a European journal of chemical biology 2003;4(12):1326-31.
2003: Carsten Bolm; Dirk Müller; Christian Dalhoff; Christian P R Hackenberger; Elmar Weinhold
The stability of pseudopeptides bearing sulfoximines as chiral backbone modifying element towards proteinase K.
Bioorganic & medicinal chemistry letters 2003;13(19):3207-11.
2003: Christine Beuck; Ishwar Singh; Anupam Bhattacharya; Walburga Hecker; Virinder S Parmar; Oliver Seitz; Elmar Weinhold
Polycyclic aromatic DNA-base surrogates: high-affinity binding to an adenine-specific base-flipping DNA methyltransferase.
Angewandte Chemie (International ed. in English) 2003;42(33):3958-60.
2003: Christine Beuck; Elmar Weinhold
Convenient synthesis of oligodeoxynucleotides containing 2'-deoxy-6-thioinosine.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):635-9.
2003: Goran Pljevaljcic; Marc Pignot; Elmar Weinhold
Design of a new fluorescent cofactor for DNA methyltransferases and sequence-specific labeling of DNA.
Journal of the American Chemical Society 2003;125(12):3486-92.
2001: Giedrius Vilkaitis; Egle Merkiene; Saulius Serva; Elmar Weinhold; Saulius Klimasauskas
The mechanism of DNA cytosine-5 methylation. Kinetic and mutational dissection of Hhai methyltransferase.
The Journal of biological chemistry 2001;276(24):20924-34.
2001: J Wölcke; Elmar Weinhold
A DNA-binding peptide from a phage display library.
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):1239-41.
2001: K Goedecke; M Pignot; Roger S Goody; Axel J Scheidig; Elmar Weinhold
Structure of the N6-adenine DNA methyltransferase M.TaqI in complex with DNA and a cofactor analog.
Nature structural biology 2001;8(2):121-5.
2000: Giedrius Vilkaitis; A Dong; Elmar Weinhold; Xiaodong Cheng; Saulius Klimasauskas
Functional roles of the conserved threonine 250 in the target recognition domain of HhaI DNA methyltransferase.
The Journal of biological chemistry 2000;275(49):38722-30.
1999: B Holz; N Dank; J E Eickhoff; Georg Lipps; G Krauss; Elmar Weinhold
Identification of the binding site for the extrahelical target base in N6-adenine DNA methyltransferases by photo-cross-linking with duplex oligodeoxyribonucleotides containing 5-iodouracil at the target position.
The Journal of biological chemistry 1999;274(21):15066-72.
1999: H Pues; Nathalie Bleimling; B Holz; J Wölcke; Elmar Weinhold
Functional roles of the conserved aromatic amino acid residues at position 108 (motif IV) and position 196 (motif VIII) in base flipping and catalysis by the N6-adenine DNA methyltransferase from Thermus aquaticus.
Biochemistry 1999;38(5):1426-34.
1998: Saulius Serva; Elmar Weinhold; Richard J Roberts; Saulius Klimasauskas
Chemical display of thymine residues flipped out by DNA methyltransferases.
Nucleic acids research 1998;26(15):3473-9.
1998: B Holz; Saulius Klimasauskas; Saulius Serva; Elmar Weinhold
2-Aminopurine as a fluorescent probe for DNA base flipping by methyltransferases.
Nucleic acids research 1998;26(4):1076-83.
1997: H Pues; B Holz; Elmar Weinhold
Construction of a deletion library using a mixture of 5'-truncated primers for inverse PCR (IPCR).
Nucleic acids research 1997;25(6):1303-4.
1997: G Schluckebier; M Kozak; Nathalie Bleimling; Elmar Weinhold; Wolfram Saenger
Differential binding of S-adenosylmethionine S-adenosylhomocysteine and Sinefungin to the adenine-specific DNA methyltransferase M.TaqI.
Journal of molecular biology 1997;265(1):56-67.