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Bernard Weinstein

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
17
Han, EK
16
Soh, Jae-Won
15
Sgambato, A
15
Deguchi, Atsuko
15
Lim, Jin
14
Arber, Nadir
13
Santella, Regina
13
Suzui, Masumi
11
Shimizu, Masahito
11
Delohery, Thomas
11
Doki, Y
9
Begemann, M
9
Kennelly, Edward
9
Masuda, Muneyuki
9
O'Brian, Catherine

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Publications

TOP 3
Adachi Seiji; Shimizu Masahito; Shirakami Yohei; Yamauchi Junichi; Natsume Hideo; Matsushima-Nishiwaki Rie; To Satoshi; Weinstein I Bernard; Moriwaki Hisataka; Kozawa Osamu
(-)-Epigallocatechin gallate downregulates EGF receptor via phosphorylation at Ser1046/1047 by p38 MAPK in colon cancer cells.
Wang Lin; Li Haiyang; Zhang Yujing; Santella Regina M; Weinstein I Bernard
HINT1 inhibits beta-catenin/TCF4, USF2 and NFkappaB activity in human hepatoma cells.
Cen Bo; Li Haiyang; Weinstein I Bernard
Histidine triad nucleotide-binding protein 1 up-regulates cellular levels of p27KIP1 by targeting ScfSKP2 ubiquitin ligase and Src.

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All Publications

2009: Adachi Seiji; Shimizu Masahito; Shirakami Yohei; Yamauchi Junichi; Natsume Hideo; Matsushima-Nishiwaki Rie; To Satoshi; Weinstein I Bernard; Moriwaki Hisataka; Kozawa Osamu
(-)-Epigallocatechin gallate downregulates EGF receptor via phosphorylation at Ser1046/1047 by p38 MAPK in colon cancer cells.
Carcinogenesis 2009;30(9):1544-52.
2009: Wang Lin; Li Haiyang; Zhang Yujing; Santella Regina M; Weinstein I Bernard
HINT1 inhibits beta-catenin/TCF4, USF2 and NFkappaB activity in human hepatoma cells.
International journal of cancer. Journal international du cancer 2009;124(7):1526-34.
2009: Cen Bo; Li Haiyang; Weinstein I Bernard
Histidine triad nucleotide-binding protein 1 up-regulates cellular levels of p27KIP1 by targeting ScfSKP2 ubiquitin ligase and Src.
The Journal of biological chemistry 2009;284(8):5265-76.
2008: Li Haiyang; Balajee Adayabalam S; Su Tao; Cen Bo; Hei Tom K; Weinstein I Bernard
The HINT1 tumor suppressor regulates both gamma-H2AX and ATM in response to DNA damage.
The Journal of cell biology 2008;183(2):253-65.
2008: Adachi Seiji; Nagao Tomokazu; To Satoshi; Joe Andrew K; Shimizu Masahito; Matsushima-Nishiwaki Rie; Kozawa Osamu; Moriwaki Hisataka; Maxfield Frederick R; Weinstein I Bernard
(-)-Epigallocatechin gallate causes internalization of the epidermal growth factor receptor in human colon cancer cells.
Carcinogenesis 2008;29(10):1986-93.
2008: Weinstein I Bernard; Case Kathleen
The history of Cancer Research: introducing an AACR Centennial series.
Cancer research 2008;68(17):6861-2.
2008: Cen Bo; Deguchi Atsuko; Weinstein I Bernard
Activation of protein kinase G Increases the expression of p21CIP1, p27KIP1, and histidine triad protein 1 through Sp1.
Cancer research 2008;68(13):5355-62.
2008: Soh Jae-Won; Kazi Julhash U; Li Han; Thompson W Joseph; Weinstein I Bernard
Celecoxib-induced growth inhibition in SW480 colon cancer cells is associated with activation of protein kinase G.
Molecular carcinogenesis 2008;47(7):519-25.
2008: Weinstein I Bernard; Joe Andrew
Oncogene addiction.
Cancer research 2008;68(9):3077-80; discussion 3080.
2008: Voloshyna Iryna; Besana Alessandra; Castillo Mireia; Matos Tulio; Weinstein I Bernard; Mansukhani Mahesh; Robinson Richard B; Cordon-Cardo Carlos; Feinmark Steven J
TREK-1 is a novel molecular target in prostate cancer.
Cancer research 2008;68(4):1197-203.
2007: Yoon Angela J; Shen Jing; Santella Regina M; Zegarelli David J; Chen Rongzhen; Weinstein I B
Activated checkpoint kinase 2 expression and risk for oral squamous cell carcinoma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(12):2768-72.
2007: Einbond Linda Saxe; Su Tao; Wu Hsan-au; Friedman Richard; Wang Xiaomei; Ramirez Alejandro; Kronenberg Fredi; Weinstein I Bernard
The growth inhibitory effect of actein on human breast cancer cells is associated with activation of stress response pathways.
International journal of cancer. Journal international du cancer 2007;121(9):2073-83.
2007: Yamazaki Kenji; Shimizu Masahito; Okuno Masataka; Matsushima-Nishiwaki Rie; Kanemura Nobuhiro; Araki Hiroshi; Tsurumi Hisashi; Kojima Soichi; Weinstein I Bernard; Moriwaki Hisataka
Synergistic effects of RXR alpha and PPAR gamma ligands to inhibit growth in human colon cancer cells--phosphorylated RXR alpha is a critical target for colon cancer management.
Gut 2007;56(11):1557-63.
2007: Masuda Muneyuki; Ruan Hong-Ying; Ito Aya; Nakashima Torahiko; Toh Satoshi; Wakasaki Takahiro; Yasumatsu Ryuji; Kutratomi Yuichiro; Komune Shizuo; Weinstein I Bernard
Signal transducers and activators of transcription 3 up-regulates vascular endothelial growth factor production and tumor angiogenesis in head and neck squamous cell carcinoma.
Oral oncology 2007;43(8):785-90.
2007: Adachi Seiji; Nagao Tomokazu; Ingolfsson Helgi I; Maxfield Frederick R; Andersen Olaf S; Kopelovich Levy; Weinstein I Bernard
The inhibitory effect of (-)-epigallocatechin gallate on activation of the epidermal growth factor receptor is associated with altered lipid order in HT29 colon cancer cells.
Cancer research 2007;67(13):6493-501.
2007: Wang Lin; Zhang Yujing; Li Haiyang; Xu Zhiheng; Santella Regina M; Weinstein I Bernard
Hint1 inhibits growth and activator protein-1 activity in human colon cancer cells.
Cancer research 2007;67(10):4700-8.
2007: Einbond Linda Saxe; Su Tao; Wu Hsan-Au; Friedman Richard; Wang Xiaomei; Jiang Bei; Hagan Timothy; Kennelly Edward J; Kronenberg Fredi; Weinstein I Bernard
Gene expression analysis of the mechanisms whereby black cohosh inhibits human breast cancer cell growth.
Anticancer research 2007;27(2):697-712.
2007: Su Tao; Deguchi Atsuko; Yao Yao; Luo Jingqing; Weinstein I Bernard
Dip1 inhibits growth and gene transcription in MCF-7 breast cancer cells.
Journal of experimental therapeutics & oncology 2007;6(2):117-27.
2006: Li Haiyang; Weinstein I Bernard
Protein kinase C beta enhances growth and expression of cyclin D1 in human breast cancer cells.
Cancer research 2006;66(23):11399-408.
2006: Einbond Linda Saxe; Shimizu Masahito; Nuntanakorn Paiboon; Seter Colette; Cheng Rong; Jiang Bei; Kronenberg Fredi; Kennelly Edward J; Weinstein I Bernard
Actein and a fraction of black cohosh potentiate antiproliferative effects of chemotherapy agents on human breast cancer cells.
Planta medica 2006;72(13):1200-6.
2006: Shirin Haim; Moss Steven F; Kancherla Sandy; Kancherla Kevin; Holt Peter R; Weinstein I Bernard; Sordillo Emilia M
Non-steroidal anti-inflammatory drugs have bacteriostatic and bactericidal activity against Helicobacter pylori.
Journal of gastroenterology and hepatology 2006;21(9):1388-93.
2006: Reynertson Kurt A; Wallace Alison M; Adachi Seiji; Gil Roberto R; Yang Hui; Basile Margaret J; D'Armiento Jeanine; Weinstein I Bernard; Kennelly Edward J
Bioactive depsides and anthocyanins from jaboticaba (Myrciaria cauliflora).
Journal of natural products 2006;69(8):1228-30.
2006: Yasui Masayoshi; Yamamoto Hirofumi; Ngan Chew Yee; Damdinsuren Bazarragchaa; Sugita Yurika; Fukunaga Hiroki; Gu Jinyu; Maeda Makiko; Takemasa Ichiro; Ikeda Masataka; Fujio Yasushi; Sekimoto Mitsugu; Matsuura Nariaki; Weinstein I Bernard; Monden Morito
Antisense to cyclin D1 inhibits vascular endothelial growth factor-stimulated growth of vascular endothelial cells: implication of tumor vascularization.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(15):4720-9.
2006: Weinstein I Bernard; Joe Andrew K
Mechanisms of disease: Oncogene addiction--a rationale for molecular targeting in cancer therapy.
Nature clinical practice. Oncology 2006;3(8):448-57.
2006: Lim Jin T E; Joe Andrew K; Suzui Masumi; Shimizu Masahito; Masuda Muneyuki; Weinstein I Bernard
Sulindac sulfide and exisulind inhibit expression of the estrogen and progesterone receptors in human breast cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(11 Pt 1):3478-84.
2006: Nuntanakorn Paiboon; Jiang Bei; Einbond Linda S; Yang Hui; Kronenberg Fredi; Weinstein I Bernard; Kennelly Edward J
Polyphenolic constituents of Actaea racemosa.
Journal of natural products 2006;69(3):314-8.
2006: Ruan Hong-Ying; Masuda Muneyuki; Ito Aya; Umezawa Kazuo; Nakashima Torahiko; Yasumatsu Ryuji; Kuratomi Yuichiro; Yamamoto Tomoya; Weinstein I Bernard; Komune Shizuo
Effects of a novel NF-kappaB inhibitor, dehydroxymethylepoxyquinomicin (DHMEQ), on growth, apoptosis, gene expression, and chemosensitivity in head and neck squamous cell carcinoma cell lines.
Head & neck 2006;28(2):158-65.
2006: Li H; Zhang Y; Su T; Santella R M; Weinstein I B
Hint1 is a haplo-insufficient tumor suppressor in mice.
Oncogene 2006;25(5):713-21.
2006: Xiao Danhua; Deguchi Atsuko; Gundersen Gregg G; Oehlen Bert; Arnold Lee; Weinstein I Bernard
The sulindac derivatives OSI-461, OSIP486823, and OSIP487703 arrest colon cancer cells in mitosis by causing microtubule depolymerization.
Molecular cancer therapeutics 2006;5(1):60-7.
2005: Shimizu Masahito; Weinstein I Bernard
Modulation of signal transduction by tea catechins and related phytochemicals.
Mutation research 2005;591(1-2):147-60.
2005: Yang Hui; Protiva Petr; Gil Roberto R; Jiang Bei; Baggett Scott; Basile Margaret J; Reynertson Kurt A; Weinstein I Bernard; Kennelly Edward J
Antioxidant and cytotoxic isoprenylated coumarins from Mammea americana.
Planta medica 2005;71(9):852-60.
2005: Xiao Danhua; Pinto John T; Gundersen Gregg G; Weinstein I Bernard
Effects of a series of organosulfur compounds on mitotic arrest and induction of apoptosis in colon cancer cells.
Molecular cancer therapeutics 2005;4(9):1388-98.
2005: Deguchi Atsuko; Xing Steven W; Shureiqi Imad; Yang Peiying; Newman Robert A; Lippman Scott M; Feinmark Steven J; Oehlen Bert; Weinstein I Bernard
Activation of protein kinase G up-regulates expression of 15-lipoxygenase-1 in human colon cancer cells.
Cancer research 2005;65(18):8442-7.
2005: Shimizu Masahito; Deguchi Atsuko; Hara Yukihiko; Moriwaki Hisataka; Weinstein I Bernard
EGCG inhibits activation of the insulin-like growth factor-1 receptor in human colon cancer cells.
Biochemical and biophysical research communications 2005;334(3):947-53.
2005: Shimizu Masahito; Deguchi Atsuko; Lim Jin T E; Moriwaki Hisataka; Kopelovich Levy; Weinstein I Bernard
(-)-Epigallocatechin gallate and polyphenon E inhibit growth and activation of the epidermal growth factor receptor and human epidermal growth factor receptor-2 signaling pathways in human colon cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(7):2735-46.
2005: Lim Jin T E; Mansukhani Mahesh; Weinstein I Bernard
Cyclin-dependent kinase 6 associates with the androgen receptor and enhances its transcriptional activity in prostate cancer cells.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(14):5156-61.
2005: Baggett Scott; Protiva Petr; Mazzola Eugene P; Yang Hui; Ressler Elizabeth T; Basile Margaret J; Weinstein I Bernard; Kennelly Edward J
Bioactive benzophenones from Garcinia xanthochymus fruits.
Journal of natural products 2005;68(3):354-60.
2005: Shimizu Masahito; Deguchi Atsuko; Joe Andrew K; Mckoy Judith F; Moriwaki Hisataka; Weinstein I Bernard
EGCG inhibits activation of HER3 and expression of cyclooxygenase-2 in human colon cancer cells.
Journal of experimental therapeutics & oncology 2005;5(1):69-78.
2004: Guang Wei; Wang Hongyan; Su Tao; Weinstein I Bernard; Wang Jia Bei
Role of mPKCI, a novel mu-opioid receptor interactive protein, in receptor desensitization, phosphorylation, and morphine-induced analgesia.
Molecular pharmacology 2004;66(5):1285-92.
2004: Shimizu Masahito; Suzui Masumi; Deguchi Atsuko; Lim Jin T E; Xiao Danhua; Hayes Julia H; Papadopoulos Kyriakos P; Weinstein I Bernard
Synergistic effects of acyclic retinoid and OSI-461 on growth inhibition and gene expression in human hepatoma cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(19):6710-21.
2004: Jiang Xiao-Hua; Tu Shui-Ping; Cui Jian-Tao; Lin Marie C M; Xia Harry H X; Wong Wai Man; Chan Annie On-On; Yuen Man Fung; Jiang Shi-Hu; Lam Shiu-Kum; Kung Hsiang-Fu; Soh Jae Won; Weinstein I Bernard; Wong Benjamin Chun-Yu
Antisense targeting protein kinase C alpha and beta1 inhibits gastric carcinogenesis.
Cancer research 2004;64(16):5787-94.
2004: Deguchi Atsuko; Thompson W Joseph; Weinstein I Bernard
Activation of protein kinase G is sufficient to induce apoptosis and inhibit cell migration in colon cancer cells.
Cancer research 2004;64(11):3966-73.
2004: Suzui Masumi; Shimizu Masahito; Masuda Muneyuki; Lim Jin T E; Yoshimi Naoki; Weinstein I Bernard
Acyclic retinoid activates retinoic acid receptor beta and induces transcriptional activation of p21(CIP1) in HepG2 human hepatoma cells.
Molecular cancer therapeutics 2004;3(3):309-16.
2004: Weinstein I Bernard; Li Haiyang
Mast cells provide a "HINT" to the function of an exotic nucleotide.
Immunity 2004;20(2):119-20.
2004: Shimizu Masahito; Suzui Masumi; Deguchi Atsuko; Lim Jin T E; Weinstein I Bernard
Effects of acyclic retinoid on growth, cell cycle control, epidermal growth factor receptor signaling, and gene expression in human squamous cell carcinoma cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(3):1130-40.
2004: Einbond Linda Saxe; Shimizu Masahito; Xiao Danhua; Nuntanakorn Paiboon; Lim Jin T E; Suzui Masumi; Seter Colette; Pertel Thomas; Kennelly Edward J; Kronenberg Fredi; Weinstein I Bernard
Growth inhibitory activity of extracts and purified components of black cohosh on human breast cancer cells.
Breast cancer research and treatment 2004;83(3):221-31.
2004: Gammon Marilie D; Terry Mary Beth; Arber Nadir; Chow Wong-Ho; Risch Harvey A; Vaughan Thomas L; Schoenberg Janet B; Mayne Susan T; Stanford Janet L; Dubrow Robert; Rotterdam Heidrun; West A Brian; Fraumeni Joseph F; Weinstein I Bernard; Hibshoosh Hanina
Nonsteroidal anti-inflammatory drug use associated with reduced incidence of adenocarcinomas of the esophagus and gastric cardia that overexpress cyclin D1: a population-based study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2004;13(1):34-9.
2003: Yang Hui; Protiva Petr; Cui Baoliang; Ma Cuiying; Baggett Scott; Hequet Vanessa; Mori Scott; Weinstein I Bernard; Kennelly Edward J
New bioactive polyphenols from Theobroma grandiflorum ("cupuaçu").
Journal of natural products 2003;66(11):1501-4.
2003: Xiao Danhua; Pinto John T; Soh Jae-Won; Deguchi Atsuko; Gundersen Gregg G; Palazzo Alexander F; Yoon Jung-Taek; Shirin Haim; Weinstein I Bernard
Induction of apoptosis by the garlic-derived compound S-allylmercaptocysteine (SAMC) is associated with microtubule depolymerization and c-Jun NH(2)-terminal kinase 1 activation.
Cancer research 2003;63(20):6825-37.
2003: Lim Jin T E; Piazza Gary A; Pamukcu Rifat; Thompson W Joseph; Weinstein I Bernard
Exisulind and related compounds inhibit expression and function of the androgen receptor in human prostate cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(13):4972-82.
2003: Soh Jae-Won; Weinstein I Bernard
Roles of specific isoforms of protein kinase C in the transcriptional control of cyclin D1 and related genes.
The Journal of biological chemistry 2003;278(36):34709-16.
2003: Masuda Muneyuki; Suzui Masumi; Lim Jin T E; Weinstein I Bernard
Epigallocatechin-3-gallate inhibits activation of HER-2/neu and downstream signaling pathways in human head and neck and breast carcinoma cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(9):3486-91.
2003: Ma Jun; Luo Xiao-Dong; Protiva Petr; Yang Hui; Ma Cuiying; Basile Margaret J; Weinstein I Bernard; Kennelly Edward J
Bioactive novel polyphenols from the fruit of Manilkara zapota (Sapodilla).
Journal of natural products 2003;66(7):983-6.
2003: Su Tao; Suzui Masumi; Wang Lei; Lin Chyuan-Sheng; Xing Wang-Qiu; Weinstein I Bernard
Deletion of histidine triad nucleotide-binding protein 1/PKC-interacting protein in mice enhances cell growth and carcinogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(13):7824-9.
2003: Page Kristen; Li Jing; Zhou Limei; Iasvovskaia Svetlana; Corbit Kevin C; Soh Jae-Won; Weinstein I Bernard; Brasier Allan R; Lin Anning; Hershenson Marc B;
Regulation of airway epithelial cell NF-kappa B-dependent gene expression by protein kinase C delta.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(11):5681-9.
2003: Soh Jae-Won; Lee Yun-Sil; Weinstein I Bernard
Effects of regulatory domains of specific isoforms of protein kinase C on growth control and apoptosis in MCF-7 breast cancer cells.
Journal of experimental therapeutics & oncology 2003;3(3):115-26.
2003: Shinozaki Hiroharu; Yang Kan; Fan Kunhua; Edelmann Winfried; Kucherlapati Raju; Weinstein I Bernard; Lipkin Martin
Cyclin D1 expression in the intestinal mucosa and tumors of Apc1638N mice.
Anticancer research 2003;23(3B):2217-26.
2003: Joe Andrew K; Liu Hui; Xiao Danhua; Soh Jae-Won; Pinto John T; Beer David G; Piazza Gary A; Thompson W Joseph; Weinstein I Bernard
Exisulind and CP248 induce growth inhibition and apoptosis in human esophageal adenocarcinoma and squamous carcinoma cells.
Journal of experimental therapeutics & oncology 2003;3(2):83-94.
2003: Shirin Haim; Hibshoosh Hanina; Kawabata Yuichi; Weinstein I Bernard; Moss Steven F
p16Ink4a is overexpressed in H. pylori-associated gastritis and is correlated with increased epithelial apoptosis.
Helicobacter 2003;8(1):66-71.
2003: Christov Konstantin; Ikui Amy; Shilkaitis Anne; Green Albert; Yao Ruisheng; You Ming; Grubbs Clinton; Steele Vernon; Lubet Ronald; Weinstein I Bernard
Cell proliferation, apoptosis, and expression of cyclin D1 and cyclin E as potential biomarkers in tamoxifen-treated mammary tumors.
Breast cancer research and treatment 2003;77(3):253-64.
2003: Tashiro Etsu; Maruki Hiroko; Minato Yusuke; Doki Yuichiro; Weinstein I Bernard; Imoto Masaya
Overexpression of cyclin D1 contributes to malignancy by up-regulation of fibroblast growth factor receptor 1 via the pRB/E2F pathway.
Cancer research 2003;63(2):424-31.
2003: Soh Jae-Won; Weinstein I Bernard
Role of COX-independent targets of NSAIDs and related compounds in cancer prevention and treatment.
Progress in experimental tumor research. Fortschritte der experimentellen Tumorforschung. Progrès de la recherche expérimentale des tumeurs 2003;37():261-85.
2002: Masuda Muneyuki; Suzui Masumi; Lim Jin T E; Deguchi Atsuko; Soh Jae-Won; Weinstein I Bernard
Epigallocatechin-3-gallate decreases VEGF production in head and neck and breast carcinoma cells by inhibiting EGFR-related pathways of signal transduction.
Journal of experimental therapeutics & oncology 2002;2(6):350-9.
2002: Yuan L W; Soh Jae-Won; Weinstein I Bernard
Inhibition of histone acetyltransferase function of p300 by PKCdelta.
Biochimica et biophysica acta 2002;1592(2):205-11.
2002: Jiang Xiao-Hua; Lam Shiu-Kum; Lin Marie C M; Jiang Shi-Hu; Kung Hsiang-Fu; Slosberg Eric D; Soh Jae Won; Weinstein I Bernard; Wong Benjamin Chun-Yu
Novel target for induction of apoptosis by cyclo-oxygenase-2 inhibitor SC-236 through a protein kinase C-beta(1)-dependent pathway.
Oncogene 2002;21(39):6113-22.
2002: Deguchi Atsuko; Soh Jae-Won; Li Han; Pamukcu Rifat; Thompson W Joseph; Weinstein I Bernard
Vasodilator-stimulated phosphoprotein (VASP) phosphorylation provides a biomarker for the action of exisulind and related agents that activate protein kinase G.
Molecular cancer therapeutics 2002;1(10):803-9.
2002: Page Kristen; Li Jing; Corbit Kevin C; Rumilla Kandelaria M; Soh Jae-Won; Weinstein I Bernard; Albanese Chris; Pestell Richard G; Rosner Marsha R; Hershenson Marc B
Regulation of airway smooth muscle cyclin D1 transcription by protein kinase C-delta.
American journal of respiratory cell and molecular biology 2002;27(2):204-13.
2002: Suzui Masumi; Masuda Muneyuki; Lim Jin T E; Albanese Chris; Pestell Richard G; Weinstein I Bernard
Growth inhibition of human hepatoma cells by acyclic retinoid is associated with induction of p21(CIP1) and inhibition of expression of cyclin D1.
Cancer research 2002;62(14):3997-4006.
2002: Weinstein I Bernard
Cancer. Addiction to oncogenes--the Achilles heal of cancer.
Science (New York, N.Y.) 2002;297(5578):63-4.
2002: Masuda Muneyuki; Suzui Masumi; Yasumatu Ryuji; Nakashima Torahiko; Kuratomi Yuichiro; Azuma Kaoru; Tomita Kichinobu; Komiyama Sohtaro; Weinstein I Bernard
Constitutive activation of signal transducers and activators of transcription 3 correlates with cyclin D1 overexpression and may provide a novel prognostic marker in head and neck squamous cell carcinoma.
Cancer research 2002;62(12):3351-5.
2002: Yoon Jung-Taek; Palazzo Alexander F; Xiao Danhua; Delohery Thomas M; Warburton Peter E; Bruce Jeffrey N; Thompson W Joseph; Sperl Gerhard; Whitehead Clark; Fetter John; Pamukcu Rifat; Gundersen Gregg G; Weinstein I Bernard
CP248, a derivative of exisulind, causes growth inhibition, mitotic arrest, and abnormalities in microtubule polymerization in glioma cells.
Molecular cancer therapeutics 2002;1(6):393-404.
2002: Shintani Masafum; Okazaki Aki; Masuda Tohru; Kawada Manabu; Ishizuka Masaaki; Doki Yuichiro; Weinstein I Bernard; Imoto Masaya
Overexpression of cyclin DI contributes to malignant properties of esophageal tumor cells by increasing VEGF production and decreasing Fas expression.
Anticancer research 2002;22(2A):639-47.
2002: Masuda Muneyuki; Toh Satoshi; Koike Koji; Kuratomi Yuichiro; Suzui Masumi; Deguchi Atsuko; Komiyama Sohtaro; Weinstein I Bernard
The roles of JNK1 and Stat3 in the response of head and neck cancer cell lines to combined treatment with all-trans-retinoic acid and 5-fluorouracil.
Japanese journal of cancer research : Gann 2002;93(3):329-39.
2002: Joe Andrew K; Liu Hui; Suzui Masumi; Vural Muhammet E; Xiao Danhua; Weinstein I Bernard
Resveratrol induces growth inhibition, S-phase arrest, apoptosis, and changes in biomarker expression in several human cancer cell lines.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(3):893-903.
2002: Deguchi Atsuko; Segawa Kaoru; Hosaka Kohei; Weinstein I Bernard; Umezawa Kazuo
Overexpression of phosphatidylinositol synthase enhances growth and G1 progression in NIH3T3 cells.
Japanese journal of cancer research : Gann 2002;93(2):157-66.
2001: Masuda M; Suzui M; Weinstein I B
Effects of epigallocatechin-3-gallate on growth, epidermal growth factor receptor signaling pathways, gene expression, and chemosensitivity in human head and neck squamous cell carcinoma cell lines.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(12):4220-9.
2001: Joe A K; Arber N; Bose S; Heitjan D; Zhang Y; Weinstein I B; Hibshoosh H
Cyclin D1 overexpression is more prevalent in non-Caucasian breast cancer.
Anticancer research 2001;21(5):3535-9.
2001: Antman K; Benson M C; Chabot J; Cobrinik D; Grann V R; Jacobson J S; Joe A K; Katz A E; Kelly K; Neugut A I; Russo D; Tiersten A; Weinstein I B
Complementary and alternative medicine: the role of the cancer center.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(18 Suppl):55S-60S.
2001: Goluboff E T; Prager D; Rukstalis D; Giantonio B; Madorsky M; Barken I; Weinstein I B; Partin A W; Olsson C A;
Safety and efficacy of exisulind for treatment of recurrent prostate cancer after radical prostatectomy.
The Journal of urology 2001;166(3):882-6.
2001: Ikui A E; Yao Y; Zhou P; Weinstein I B
Induction of apoptosis by sulindac sulfide in HL60 cells is enhanced by p21CiP1 or p27KiP1.
Anticancer research 2001;21(4A):2297-303.
2001: Luo J; Soh J W; Xing W Q; Mao Y; Matsuno T; Weinstein I B
PM-3, a benzo-gamma-pyran derivative isolated from propolis, inhibits growth of MCF-7 human breast cancer cells.
Anticancer research 2001;21(3B):1665-71.
2001: Soh J W; Mao Y; Liu L; Thompson W J; Pamukcu R; Weinstein I B
Protein kinase G activates the JNK1 pathway via phosphorylation of MEKK1.
The Journal of biological chemistry 2001;276(19):16406-10.
2001: Miyata H; Doki Y; Yamamoto H; Kishi K; Takemoto H; Fujiwara Y; Yasuda T; Yano M; Inoue M; Shiozaki H; Weinstein I B; Monden M
Overexpression of CDC25B overrides radiation-induced G2-M arrest and results in increased apoptosis in esophageal cancer cells.
Cancer research 2001;61(7):3188-93.
2001: Shirin H; Pinto J T; Kawabata Y; Soh J W; Delohery T; Moss S F; Murty V; Rivlin R S; Holt P R; Weinstein I B
Antiproliferative effects of S-allylmercaptocysteine on colon cancer cells when tested alone or in combination with sulindac sulfide.
Cancer research 2001;61(2):725-31.
2000: Soh J W; Mao Y; Kim M G; Pamukcu R; Li H; Piazza G A; Thompson W J; Weinstein I B
Cyclic GMP mediates apoptosis induced by sulindac derivatives via activation of c-Jun NH2-terminal kinase 1.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(10):4136-41.
2000: Shirin H; Sordillo E M; Kolevska T K; Hibshoosh H; Kawabata Y; Oh S H; Kuebler J F; Delohery T; Weghorst C M; Weinstein I B; Moss S F
Chronic Helicobacter pylori infection induces an apoptosis-resistant phenotype associated with decreased expression of p27(kip1).
Infection and immunity 2000;68(9):5321-8.
2000: Corbit K C; Soh J W; Yoshida K; Eves E M; Weinstein I B; Rosner M R
Different protein kinase C isoforms determine growth factor specificity in neuronal cells.
Molecular and cellular biology 2000;20(15):5392-403.
2000: Yao Y; Doki Y; Jiang W; Imoto M; Venkatraj V S; Warburton D; Santella R M; Lu B; Yan L; Sun X H; Su T; Luo J; Weinstein I B
Cloning and characterization of DIP1, a novel protein that is related to the Id family of proteins.
Experimental cell research 2000;257(1):22-32.
2000: Weinstein I B
Disorders in cell circuitry during multistage carcinogenesis: the role of homeostasis.
Carcinogenesis 2000;21(5):857-64.
2000: Slosberg E D; Yao Y; Xing F; Ikui A; Jirousek M R; Weinstein I B
The protein kinase C beta-specific inhibitor LY379196 blocks TPA-induced monocytic differentiation of HL60 cells the protein kinase C beta-specific inhibitor LY379196 blocks TPA-induced monocytic differentiation of HL60 cells.
Molecular carcinogenesis 2000;27(3):166-76.
2000: Zhu G H; Wong B C; Slosberg E D; Eggo M C; Ching C K; Yuen S T; Lai K C; Soh J W; Weinstein I B; Lam S K
Overexpression of protein kinase C-beta1 isoenzyme suppresses indomethacin-induced apoptosis in gastric epithelial cells.
Gastroenterology 2000;118(3):507-14.
2000: Perera F P; Weinstein I B
Molecular epidemiology: recent advances and future directions.
Carcinogenesis 2000;21(3):517-24.
2000: Endo N; Tashiro E; Umezawa K; Kawada M; Uehara Y; Doki Y; Weinstein I B; Imoto M
Herbimycin A induces G1 arrest through accumulation of p27(Kip1) in cyclin D1-overexpressing fibroblasts.
Biochemical and biophysical research communications 2000;267(1):54-8.
1999: Arber N; Hibshoosh H; Yasui W; Neugut A I; Hibshoosh A; Yao Y; Sgambato A; Yamamoto H; Shapira I; Rosenman D; Fabian I; Weinstein I B; Tahara E; Holt P R
Abnormalities in the expression of cell cycle-related proteins in tumors of the small bowel.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1999;8(12):1101-5.
1999: Zhou P; Yao Y; Soh J W; Weinstein I B
Overexpression of p21Cip1 or p27Kip1 in the promyelocytic leukemia cell line HL60 accelerates its lineage-specific differentiation.
Anticancer research 1999;19(6B):4935-45.
1999: Slosberg E D; Klein M G; Yao Y; Han E K; Schieren I; Weinstein I B
The alpha isoform of protein kinase C mediates phorbol ester-induced growth inhibition and p21cip1 induction in HC11 mammary epithelial cells.
Oncogene 1999;18(48):6658-66.
1999: Lim J T; Piazza G A; Han E K; Delohery T M; Li H; Finn T S; Buttyan R; Yamamoto H; Sperl G J; Brendel K; Gross P H; Pamukcu R; Weinstein I B
Sulindac derivatives inhibit growth and induce apoptosis in human prostate cancer cell lines.
Biochemical pharmacology 1999;58(7):1097-107.
1999: Yao Y; Slosberg E D; Wang L; Hibshoosh H; Zhang Y J; Xing W Q; Santella R M; Weinstein I B
Increased susceptibility to carcinogen-induced mammary tumors in MMTV-Cdc25B transgenic mice.
Oncogene 1999;18(37):5159-66.
1999: Arber N; Gammon M D; Hibshoosh H; Britton J A; Zhang Y; Schonberg J B; Roterdam H; Fabian I; Holt P R; Weinstein I B
Overexpression of cyclin D1 occurs in both squamous carcinomas and adenocarcinomas of the esophagus and in adenocarcinomas of the stomach.
Human pathology 1999;30(9):1087-92.
1999: Yamamoto H; Soh J W; Monden T; Klein M G; Zhang L M; Shirin H; Arber N; Tomita N; Schieren I; Stein C A; Weinstein I B
Paradoxical increase in retinoblastoma protein in colorectal carcinomas may protect cells from apoptosis.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(7):1805-15.
1999: Han E K; Ng S C; Arber N; Begemann M; Weinstein I B
Roles of cyclin D1 and related genes in growth inhibition, senescence and apoptosis.
Apoptosis : an international journal on programmed cell death 1999;4(3):213-9.
1999: Shirin H; Sordillo E M; Oh S H; Yamamoto H; Delohery T; Weinstein I B; Moss S F
Helicobacter pylori inhibits the G1 to S transition in AGS gastric epithelial cells.
Cancer research 1999;59(10):2277-81.
1999: Goluboff E T; Shabsigh A; Saidi J A; Weinstein I B; Mitra N; Heitjan D; Piazza G A; Pamukcu R; Buttyan R; Olsson C A
Exisulind (sulindac sulfone) suppresses growth of human prostate cancer in a nude mouse xenograft model by increasing apoptosis.
Urology 1999;53(2):440-5.
1999: Soh J W; Lee E H; Prywes R; Weinstein I B
Novel roles of specific isoforms of protein kinase C in activation of the c-fos serum response element.
Molecular and cellular biology 1999;19(2):1313-24.
1999: Yamamoto H; Soh J W; Shirin H; Xing W Q; Lim J T; Yao Y; Slosberg E; Tomita N; Schieren I; Weinstein I B
Comparative effects of overexpression of p27Kip1 and p21Cip1/Waf1 on growth and differentiation in human colon carcinoma cells.
Oncogene 1999;18(1):103-15.
1998: Nomoto K; Tomita N; Miyake M; Xhu D B; LoGerfo P R; Weinstein I B
Growth inhibition, enhancement of intercellular adhesion, and increased expression of carcinoembryonic antigen by overexpression of phosphoinositides-specific phospholipase C beta 1 in LS174T human colon adenocarcinoma cell line.
Japanese journal of cancer research : Gann 1998;89(12):1257-66.
1998: Klein M G; Yao Y; Slosberg E D; Lima C D; Doki Y; Weinstein I B
Characterization of PKCI and comparative studies with FHIT, related members of the HIT protein family.
Experimental cell research 1998;244(1):26-32.
1998: Begemann M; Kashimawo S A; Lunn R M; Delohery T; Choi Y J; Kim S; Heitjan D F; Santella R M; Schiff P B; Bruce J N; Weinstein I B
Growth inhibition induced by Ro 31-8220 and calphostin C in human glioblastoma cell lines is associated with apoptosis and inhibition of CDC2 kinase.
Anticancer research 1998;18(5A):3139-52.
1998: Sgambato A; Zhang Y J; Ciaparrone M; Soh J W; Cittadini A; Santella R M; Weinstein I B
Overexpression of p27Kip1 inhibits the growth of both normal and transformed human mammary epithelial cells.
Cancer research 1998;58(15):3448-54.
1998: Begemann M; Kashimawo S A; Heitjan D F; Schiff P B; Bruce J N; Weinstein I B
Treatment of human glioblastoma cells with the staurosporine derivative CGP 41251 inhibits CDC2 and CDK2 kinase activity and increases radiation sensitivity.
Anticancer research 1998;18(4A):2275-82.
1998: Cacace A M; Ueffing M; Han E K; Marmè D; Weinstein I B
Overexpression of PKCepsilon in R6 fibroblasts causes increased production of active TGFbeta.
Journal of cellular physiology 1998;175(3):314-22.
1998: Han E K; Lim J T; Arber N; Rubin M A; Xing W Q; Weinstein I B
Cyclin D1 expression in human prostate carcinoma cell lines and primary tumors.
The Prostate 1998;35(2):95-101.
1998: Han E K; Arber N; Yamamoto H; Lim J T; Delohery T; Pamukcu R; Piazza G A; Xing W Q; Weinstein I B
Effects of sulindac and its metabolites on growth and apoptosis in human mammary epithelial and breast carcinoma cell lines.
Breast cancer research and treatment 1998;48(3):195-203.
1998: Venkatraj V S; Begemann M; Sobrino A; Bruce J N; Weinstein I B; Warburton D
Genomic changes in glioblastoma cell lines detected by comparative genomic hybridization.
Journal of neuro-oncology 1998;36(2):141-8.
1998: Ciaparrone M; Yamamoto H; Yao Y; Sgambato A; Cattoretti G; Tomita N; Monden T; Rotterdam H; Weinstein I B
Localization and expression of p27KIP1 in multistage colorectal carcinogenesis.
Cancer research 1998;58(1):114-22.
1997: Weinstein I B; Begemann M; Zhou P; Han E K; Sgambato A; Doki Y; Arber N; Ciaparrone M; Yamamoto H
Disorders in cell circuitry associated with multistage carcinogenesis: exploitable targets for cancer prevention and therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(12 Pt 2):2696-702.
1997: Arber N; Han E K; Sgambato A; Piazza G A; Delohery T M; Begemann M; Weghorst C M; Kim N H; Pamukcu R; Ahnen D J; Reed J C; Weinstein I B; Holt P R
A K-ras oncogene increases resistance to sulindac-induced apoptosis in rat enterocytes.
Gastroenterology 1997;113(6):1892-900.
1997: Sgambato A; Zhang Y J; Arber N; Hibshoosh H; Doki Y; Ciaparrone M; Santella R M; Cittadini A; Weinstein I B
Deregulated expression of p27(Kip1) in human breast cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(10):1879-87.
1997: Imoto M; Doki Y; Jiang W; Han E K; Weinstein I B
Effects of cyclin D1 overexpression on G1 progression-related events.
Experimental cell research 1997;236(1):173-80.
1997: Arber N; Neugut A I; Weinstein I B; Holt P
Molecular genetics of small bowel cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1997;6(9):745-8.
1997: Doki Y; Imoto M; Han E K; Sgambato A; Weinstein I B
Increased expression of the P27KIP1 protein in human esophageal cancer cell lines that over-express cyclin D1.
Carcinogenesis 1997;18(6):1139-48.
1997: Arber N; Doki Y; Han E K; Sgambato A; Zhou P; Kim N H; Delohery T; Klein M G; Holt P R; Weinstein I B
Antisense to cyclin D1 inhibits the growth and tumorigenicity of human colon cancer cells.
Cancer research 1997;57(8):1569-74.
1997: Sgambato A; Doki Y; Schieren I; Weinstein I B
Effects of cyclin E overexpression on cell growth and response to transforming growth factor beta depend on cell context and p27Kip1 expression.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1997;8(4):393-405.
1997: Sutter T; Doi S; Carnevale K A; Arber N; Weinstein I B
Expression of cyclins D1 and E in human colon adenocarcinomas.
Journal of medicine 1997;28(5-6):285-309.
1997: Weinstein I B; Kahn S M; O'Driscoll K; Borner C; Bang D; Jiang W; Blackwood A; Nomoto K
The role of protein kinase C in signal transduction, growth control and lipid metabolism.
Advances in experimental medicine and biology 1997;400A():313-21.
1996: Cacace A M; Ueffing M; Philipp A; Han E K; Kolch W; Weinstein I B
PKC epsilon functions as an oncogene by enhancing activation of the Raf kinase.
Oncogene 1996;13(12):2517-26.
1996: Begemann M; Kashimawo S A; Choi Y A; Kim S; Christiansen K M; Duigou G; Mueller M; Schieren I; Ghosh S; Fabbro D; Lampen N M; Heitjan D F; Schiff P B; Bruce J N; Weinstein I B
Inhibition of the growth of glioblastomas by CGP 41251, an inhibitor of protein kinase C, and by a phorbol ester tumor promoter.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(6):1017-30.
1996: Arber N; Lightdale C; Rotterdam H; Han K H; Sgambato A; Yap E; Ahsan H; Finegold J; Stevens P D; Green P H; Hibshoosh H; Neugut A I; Holt P R; Weinstein I B
Increased expression of the cyclin D1 gene in Barrett's esophagus.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1996;5(6):457-9.
1996: Han E K; Begemann M; Sgambato A; Soh J W; Doki Y; Xing W Q; Liu W; Weinstein I B
Increased expression of cyclin D1 in a murine mammary epithelial cell line induces p27kip1, inhibits growth, and enhances apoptosis.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1996;7(6):699-710.
1996: Arber N; Sutter T; Miyake M; Kahn S M; Venkatraj V S; Sobrino A; Warburton D; Holt P R; Weinstein I B
Increased expression of cyclin D1 and the Rb tumor suppressor gene in c-K-ras transformed rat enterocytes.
Oncogene 1996;12(9):1903-8.
1996: Lima C D; Klein M G; Weinstein I B; Hendrickson W A
Three-dimensional structure of human protein kinase C interacting protein 1, a member of the HIT family of proteins.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(11):5357-62.
1996: Livneh E; Shimon T; Bechor E; Doki Y; Schieren I; Weinstein I B
Linking protein kinase C to the cell cycle: ectopic expression of PKC eta in NIH3T3 cells alters the expression of cyclins and Cdk inhibitors and induces adipogenesis.
Oncogene 1996;12(7):1545-55.
1996: Sgambato A; Han E K; Zhou P; Schieren I; Weinstein I B
Overexpression of cyclin E in the HC11 mouse mammary epithelial cell line is associated with growth inhibition and increased expression of p27(Kip1).
Cancer research 1996;56(6):1389-99.
1995: Han E K; Cacace A M; Sgambato A; Weinstein I B
Altered expression of cyclins and c-fos in R6 cells that overproduce PKC epsilon.
Carcinogenesis 1995;16(10):2423-8.
1995: Sgambato A; Han E K; Zhang Y J; Moon R C; Santella R M; Weinstein I B
Deregulated expression of cyclin D1 and other cell cycle-related genes in carcinogen-induced rat mammary tumors.
Carcinogenesis 1995;16(9):2193-8.
1995: Kahn S M; Klein M G; Jiang W; Xing W Q; Xu D B; Perucho M; Weinstein I B
Design of a selectable reporter for the detection of mutations in mammalian simple repeat sequences.
Carcinogenesis 1995;16(5):1223-8.
1995: Goldstein D R; Cacace A M; Weinstein I B
Overexpression of protein kinase C beta 1 in the SW480 colon cancer cell line causes growth suppression.
Carcinogenesis 1995;16(5):1121-6.
1995: Luo J H; Xing W Q; Weinstein I B
The phorbol ester TPA markedly enhances the binding of calcium to the regulatory domain of protein kinase C beta 1 in the presence of phosphatidylserine.
Carcinogenesis 1995;16(4):897-905.
1995: Han E K; Sgambato A; Jiang W; Zhang Y J; Santella R M; Doki Y; Cacace A M; Schieren I; Weinstein I B
Stable overexpression of cyclin D1 in a human mammary epithelial cell line prolongs the S-phase and inhibits growth.
Oncogene 1995;10(5):953-61.
1995: Nomoto K; Tomita N; Miyake M; Xhu D B; LoGerfo P R; Weinstein I B
Expression of phospholipases gamma 1, beta 1, and delta 1 in primary human colon carcinomas and colon carcinoma cell lines.
Molecular carcinogenesis 1995;12(3):146-52.
1995: Borner C; Ueffing M; Jaken S; Parker P J; Weinstein I B
Two closely related isoforms of protein kinase C produce reciprocal effects on the growth of rat fibroblasts. Possible molecular mechanisms.
The Journal of biological chemistry 1995;270(1):78-86.
1994: Kahn S M; O'Driscoll K R; Jiang W; Borner C; Xu D B; Blackwood M A; Zhang Y J; Nomoto K; Weinstein I B
Suppression of mitogenic activity by stable expression of the regulatory domain of PKC beta.
Carcinogenesis 1994;15(12):2919-25.
1994: Doi S; Goldstein D; Hug H; Weinstein I B
Expression of multiple isoforms of protein kinase C in normal human colon mucosa and colon tumors and decreased levels of protein kinase C beta and eta mRNAs in the tumors.
Molecular carcinogenesis 1994;11(4):197-203.
1994: Jiang W; Zhou P; Kahn S M; Tomita N; Johnson M D; Weinstein I B
Molecular cloning of TPAR1, a gene whose expression is repressed by the tumor promoter 12-O-tetradecanoylphorbol 13-acetate (TPA).
Experimental cell research 1994;215(2):284-93.
1994: O'Driscoll K R; Madden P V; Christiansen K M; Viage A; Slaga T J; Fabbro D; Powell C T; Weinstein I B
Overexpression of protein kinase C beta I in a murine keratinocyte cell line produces effects on cellular growth, morphology and differentiation.
Cancer letters 1994;83(1-2):249-59.
1994: Nomoto K; Morotomi M; Miyake M; Xu D B; LoGerfo P P; Weinstein I B
The effects of bile acids on phospholipase C activity in extracts of normal human colon mucosa and primary colon tumors.
Molecular carcinogenesis 1994;9(2):87-94.
1994: Arita Y; O'Driscoll K R; Weinstein I B
Growth inhibition of human melanoma-derived cells by 12-O-tetradecanoyl phorbol 13-acetate.
International journal of cancer. Journal international du cancer 1994;56(2):229-35.
1993: Jiang W; Kahn S M; Zhou P; Zhang Y J; Cacace A M; Infante A S; Doi S; Santella R M; Weinstein I B
Overexpression of cyclin D1 in rat fibroblasts causes abnormalities in growth control, cell cycle progression and gene expression.
Oncogene 1993;8(12):3447-57.
1993: Luo J H; Weinstein I B
Calcium-dependent activation of protein kinase C. The role of the C2 domain in divalent cation selectivity.
The Journal of biological chemistry 1993;268(31):23580-4.
1993: Jiang W; Zhang Y J; Kahn S M; Hollstein M C; Santella R M; Lu S H; Harris C C; Montesano R; Weinstein I B
Altered expression of the cyclin D1 and retinoblastoma genes in human esophageal cancer.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(19):9026-30.
1993: Zhang Y J; Jiang W; Chen C J; Lee C S; Kahn S M; Santella R M; Weinstein I B
Amplification and overexpression of cyclin D1 in human hepatocellular carcinoma.
Biochemical and biophysical research communications 1993;196(2):1010-6.
1993: Cacace A M; Guadagno S N; Krauss R S; Fabbro D; Weinstein I B
The epsilon isoform of protein kinase C is an oncogene when overexpressed in rat fibroblasts.
Oncogene 1993;8(8):2095-104.
1993: Haspel J; Sunderman F W; Hofper S M; Henjum D C; Brandt-Rauf P W; Weinstein I B; Nishimura S; Yamaizumi Z; Pincus M R
A nickel-binding serpin, pNiXa, induces maturation of Xenopus oocytes and shows synergism with oncogenic ras-p21 protein.
Research communications in chemical pathology and pharmacology 1993;79(2):131-40.
1993: Luo J H; Kahn S; O'Driscoll K; Weinstein I B
The regulatory domain of protein kinase C beta 1 contains phosphatidylserine- and phorbol ester-dependent calcium binding activity.
The Journal of biological chemistry 1993;268(5):3715-9.
1993: Lee G; Delohery T M; Ronai Z; Brandt-Rauf P W; Pincus M R; Murphy R B; Weinstein I B
A comparison of techniques for introducing macromolecules into living cells.
Cytometry 1993;14(3):265-70.
1992: Chung D L; Joran A; Friedman F; Robinson R; Brandt-Rauf P W; Weinstein I B; Ronai Z; Baskin L; Dykes D C; Murphy R B
Evidence that oocyte maturation induced by an oncogenic ras-p21 protein and insulin is mediated by overlapping yet distinct mechanisms.
Experimental cell research 1992;203(2):329-35.
1992: Tomita N; Jiang W; Hibshoosh H; Warburton D; Kahn S M; Weinstein I B
Isolation and characterization of a highly malignant variant of the SW480 human colon cancer cell line.
Cancer research 1992;52(24):6840-7.
1992: Pincus M R; Chung D; Dykes D C; Brandt-Rauf P; Weinstein I B; Yamaizumi Z; Nishimura S
Pathways for activation of the ras-oncogene-encoded p21 protein.
Annals of clinical and laboratory science 1992;22(5):323-42.
1992: Arita Y; O'Driscoll K R; Weinstein I B
Growth of human melanocyte cultures supported by 12-O-tetradecanoylphorbol-13-acetate is mediated through protein kinase C activation.
Cancer research 1992;52(16):4514-21.
1992: Krauss R S; Guadagno S N; Weinstein I B
Novel revertants of H-ras oncogene-transformed R6-PKC3 cells.
Molecular and cellular biology 1992;12(7):3117-29.
1992: Borner C; Guadagno S N; Hsiao W W; Fabbro D; Barr M; Weinstein I B
Expression of four protein kinase C isoforms in rat fibroblasts. Differential alterations in ras-, src-, and fos-transformed cells.
The Journal of biological chemistry 1992;267(18):12900-10.
1992: Borner C; Guadagno S N; Fabbro D; Weinstein I B
Expression of four protein kinase C isoforms in rat fibroblasts. Distinct subcellular distribution and regulation by calcium and phorbol esters.
The Journal of biological chemistry 1992;267(18):12892-9.
1992: Jiang W; Kahn S M; Tomita N; Zhang Y J; Lu S H; Weinstein I B
Amplification and expression of the human cyclin D gene in esophageal cancer.
Cancer research 1992;52(10):2980-3.
1992: Chung D L; Brandt-Rauf P W; Weinstein I B; Nishimura S; Yamaizumi Z; Murphy R B; Pincus M R
Evidence that the ras oncogene-encoded p21 protein induces oocyte maturation via activation of protein kinase C.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(5):1993-6.
1992: Guadagno S N; Borner C; Weinstein I B
Altered regulation of a major substrate of protein kinase C in rat 6 fibroblasts overproducing PKC beta I.
The Journal of biological chemistry 1992;267(4):2697-707.
1992: Tchou-Wong K M; Weinstein I B
Altered expression of protein kinase C, lck, and CD45 in a 12-O-tetradecanoylphorbol-13-acetate-dependent leukemic T-cell variant that expresses a high level of interleukin-2 receptor.
Molecular and cellular biology 1992;12(1):394-401.
1992: Weinstein I B
Toxicity, cell proliferation, and carcinogenesis.
Molecular carcinogenesis 1992;5(1):2-3.
1991: Lu X Q; Levy M; Weinstein I B; Santella R M
Immunological quantitation of levels of tissue inhibitor of metalloproteinase-1 in human colon cancer.
Cancer research 1991;51(23 Pt 1):6231-5.
1991: Chung D L; Brandt-Rauf P; Murphy R B; Nishimura S; Yamaizumi Z; Weinstein I B; Pincus M R
A peptide from the GAP-binding domain of the ras-p21 protein as well as azatyrosine block ras-induced maturation of Xenopus oocytes.
Biochemical and biophysical research communications 1991;181(3):1378-84.
1991: Morotomi M; LoGerfo P; Weinstein I B
Fecal excretion, uptake and metabolism by colon mucosa of diacylglycerol in rats.
Biochemical and biophysical research communications 1991;181(3):1028-34.
1991: Choi P M; Weinstein I B
The modulation of growth by HMBA in PKC overproducing HT29 colon cancer cells.
Biochemical and biophysical research communications 1991;181(2):809-17.
1991: Hsieh L L; Shinozuka H; Weinstein I B
Changes in expression of cellular oncogenes and endogenous retrovirus-like sequences during hepatocarcinogenesis induced by a peroxisome proliferator.
British journal of cancer 1991;64(5):815-20.
1991: Weinstein I B
Cancer prevention: recent progress and future opportunities.
Cancer research 1991;51(18 Suppl):5080s-5085s.
1991: Krauss R S; Weinstein I B
A novel, plasmid-based system for studying gene rearrangements in mammalian cells.
Molecular and cellular biology 1991;11(8):3915-24.
1991: Chung D L; Brandt-Rauf P; Murphy R B; Nishimura S; Yamaizumi Z; Weinstein I B; Pincus M R
A peptide from the GAP-binding domain of the ras-p21 protein and azatyrosine block ras-induced maturation of Xenopus oocytes.
Anticancer research 1991;11(4):1373-8.
1991: Kahn S M; Jiang W; Culbertson T A; Weinstein I B; Williams G M; Tomita N; Ronai Z
Rapid and sensitive nonradioactive detection of mutant K-ras genes via 'enriched' PCR amplification.
Oncogene 1991;6(6):1079-83.
1991: Hibshoosh H; Johnson M; Weinstein I B
Effects of overexpression of ornithine decarboxylase (ODC) on growth control and oncogene-induced cell transformation.
Oncogene 1991;6(5):739-43.
1991: Hoshina S; Ueffing M; Morotomi M; Weinstein I B
Effects of a fecapentaene on protein kinase C.
Biochemical and biophysical research communications 1991;176(1):505-10.
1991: Solomon D H; O'Driscoll K; Sosne G; Weinstein I B; Cayre Y E
1 alpha,25-dihydroxyvitamin D3-induced regulation of protein kinase C gene expression during HL-60 cell differentiation.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1991;2(4):187-94.
1991: Rotenberg S A; Calogeropoulou T; Jaworski J S; Weinstein I B; Rideout D
A self-assembling protein kinase C inhibitor.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(6):2490-4.
1991: Phan S C; Morotomi M; Guillem J G; LoGerfo P; Weinstein I B
Decreased levels of 1,2-sn-diacylglycerol in human colon tumors.
Cancer research 1991;51(5):1571-3.
1991: Weinstein I B
Mitogenesis is only one factor in carcinogenesis.
Science (New York, N.Y.) 1991;251(4992):387-8.
1991: Weinstein I B
The roles of specific isoforms of protein kinase C in growth control and human colon cancer.
Princess Takamatsu symposia 1991;22():277-83.
1991: Rotenberg S A; Weinstein I B
Two polychlorinated hydrocarbons cause phospholipid-dependent protein kinase C activation in vitro in the absence of calcium.
Molecular carcinogenesis 1991;4(6):477-81.
1990: Borner C; Guadagno S N; Hsieh L L; Hsiao W L; Weinstein I B
Transformation by a ras oncogene causes increased expression of protein kinase C-alpha and decreased expression of protein kinase C-epsilon.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1990;1(12):653-60.
1990: Hoshina S; Ueffing M; Weinstein I B
Growth factor-induced DNA synthesis in cells that overproduce protein kinase C.
Journal of cellular physiology 1990;145(2):262-7.
1990: Hoshina S; Kahn S M; Jiang W; Green P H; Neu H C; Chin N; Morotomi M; LoGerfo P; Weinstein I B
Direct detection and amplification of Helicobacter pylori ribosomal 16S gene segments from gastric endoscopic biopsies.
Diagnostic microbiology and infectious disease 1990;13(6):473-9.
1990: Choi P M; Tchou-Wong K M; Weinstein I B
Overexpression of protein kinase C in HT29 colon cancer cells causes growth inhibition and tumor suppression.
Molecular and cellular biology 1990;10(9):4650-7.
1990: Ronai Z A; Weinstein I B
Identification of ultraviolet-inducible proteins that bind to a TGACAACA sequence in the polyoma virus regulatory region.
Cancer research 1990;50(17):5374-81.
1990: Morotomi M; Guillem J G; LoGerfo P; Weinstein I B
Production of diacylglycerol, an activator of protein kinase C, by human intestinal microflora.
Cancer research 1990;50(12):3595-9.
1990: Roth J S; Hsieh L L; Peraino C; Weinstein I B
Isolation of a complementary DNA encoding the catalytic subunit of protein kinase A and studies on the expression of this sequence in rat hepatomas and regenerating liver.
Cancer research 1990;50(6):1675-80.
1990: Hsiao W L; Pai H L; Matsui M S; Weinstein I B
Effects of specific fatty acids on cell transformation induced by an activated c-H-ras oncogene.
Oncogene 1990;5(3):417-21.
1990: Rotenberg S A; Krauss R S; Borner C M; Weinstein I B
Characterization of a specific form of protein kinase C overproduced by a C3H 10T1/2 cell line.
The Biochemical journal 1990;266(1):173-8.
1990: Rotenberg S A; Smiley S; Ueffing M; Krauss R S; Chen L B; Weinstein I B
Inhibition of rodent protein kinase C by the anticarcinoma agent dequalinium.
Cancer research 1990;50(3):677-85.
1990: Bloch S; Ashwanden P; Neugut A I; Field M; Rubin M; Apfelbaum T; Rubinoff M; Weinstein I B
Utilizing television to promote a community colon cancer screening program.
Progress in clinical and biological research 1990;339():311-23.
1990: Krauss R S; Housey G M; Hsiao W L; Johnson M K; Rotenberg S A; Borner C M; Weinstein I B
The role of protein kinase C in signal transduction and cellular transformation.
Progress in clinical and biological research 1990;340D():175-82.
1990: Weinstein I B
The role of protein kinase C in growth control and the concept of carcinogenesis as a progressive disorder in signal transduction.
Advances in second messenger and phosphoprotein research 1990;24():307-16.
1990: Hsieh L L; Weinstein I B
Factors influencing the expression of endogenous retrovirus-like sequences in Rat 6 cells.
Molecular carcinogenesis 1990;3(6):344-9.
1990: Guillem J G; Levy M F; Hsieh L L; Johnson M D; LoGerfo P; Forde K A; Weinstein I B
Increased levels of phorbin, c-myc, and ornithine decarboxylase RNAs in human colon cancer.
Molecular carcinogenesis 1990;3(2):68-74.
1989: Hsieh L L; Hoshina S; Weinstein I B
Phenotypic effects of overexpression of PKC beta 1 in rat liver epithelial cells.
Journal of cellular biochemistry 1989;41(4):179-88.
1989: Morotomi M; Hoshina S; Green P; Neu H C; LoGerfo P; Watanabe I; Mutai M; Weinstein I B
Oligonucleotide probe for detection and identification of Campylobacter pylori.
Journal of clinical microbiology 1989;27(12):2652-5.
1989: Lee G; Ronai Z A; Pincus M R; Brandt-Rauf P W; Murphy R B; Delohery T M; Nishimura S; Yamaizumi Z; Weinstein I B
Identification of an intracellular protein that specifically interacts with photoaffinity-labeled oncogenic p21 protein.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(22):8678-82.
1989: Krauss R S; Housey G M; Johnson M D; Weinstein I B
Disturbances in growth control and gene expression in a C3H/10T1/2 cell line that stably overproduces protein kinase C.
Oncogene 1989;4(8):991-8.
1989: Jiang W; Kahn S M; Guillem J G; Lu S H; Weinstein I B
Rapid detection of ras oncogenes in human tumors: applications to colon, esophageal, and gastric cancer.
Oncogene 1989;4(7):923-8.
1989: Hsieh L L; Wainfan E; Hoshina S; Dizik M; Weinstein I B
Altered expression of retrovirus-like sequences and cellular oncogenes in mice fed methyl-deficient diets.
Cancer research 1989;49(14):3795-9.
1989: Hsiao W L; Housey G M; Johnson M D; Weinstein I B
Cells that overproduce protein kinase C are more susceptible to transformation by an activated H-ras oncogene.
Molecular and cellular biology 1989;9(6):2641-7.
1989: Lopez C A; Hsiao W L; Weinstein I B
Effects of triiodothyronine and tamoxifen on cell transformation induced by an activated c-Ha-ras oncogene.
Cancer research 1989;49(4):895-8.
1989: Perkins A S; Kirschmeier P T; Weinstein I B
Transduction of the human insulin gene via retroviral vectors fails to yield spliced transcripts.
DNA (Mary Ann Liebert, Inc.) 1989;8(1):59-68.
1989: Lopez C A; Hsiao W L; Weinstein I B
Effects of various chemical agents on the transformation of rat fibroblasts by an activated c-Ha-ras oncogene.
Molecular carcinogenesis 1989;2(2):81-7.
1989: Fujiki H; Suganuma M; Yoshizawa S; Kanazawa H; Sugimura T; Manam S; Kahn S M; Jiang W; Hoshina S; Weinstein I B
Codon 61 mutations in the c-Harvey-ras gene in mouse skin tumors induced by 7,12-dimethylbenz[a]anthracene plus okadaic acid class tumor promoters.
Molecular carcinogenesis 1989;2(4):184-7.
1988: Yang X Y; Ronai Z A; Santella R M; Weinstein I B
Effects of 8-methoxypsoralen and ultraviolet light A on EGF receptor (HER-1) expression.
Biochemical and biophysical research communications 1988;157(2):590-6.
1988: Weinstein I B
The origins of human cancer: molecular mechanisms of carcinogenesis and their implications for cancer prevention and treatment--twenty-seventh G.H.A. Clowes memorial award lecture.
Cancer research 1988;48(15):4135-43.
1988: Guillem J G; Hsieh L L; O'Toole K M; Forde K A; LoGerfo P; Weinstein I B
Changes in expression of oncogenes and endogenous retroviral-like sequences during colon carcinogenesis.
Cancer research 1988;48(14):3964-71.
1988: O'Brian C A; Housey G M; Weinstein I B
Specific and direct binding of protein kinase C to an immobilized tamoxifen analogue.
Cancer research 1988;48(13):3626-9.
1988: Banerjee R; Hsiao W L; Weinstein I B; Grunberger D
Inhibition of c-H-ras oncogene induced transformation of rat embryo fibroblasts by cotransfected polynucleotides containing alternating purine-pyrimidine sequences.
Biochemical and biophysical research communications 1988;152(1):449-55.
1988: Kirschmeier P T; Housey G M; Johnson M D; Perkins A S; Weinstein I B
Construction and characterization of a retroviral vector demonstrating efficient expression of cloned cDNA sequences.
DNA (Mary Ann Liebert, Inc.) 1988;7(3):219-25.
1988: Ronai Z A; Weinstein I B
Identification of a UV-induced trans-acting protein that stimulates polyomavirus DNA replication.
Journal of virology 1988;62(3):1057-60.
1988: Housey G M; Johnson M D; Hsiao W L; O'Brian C A; Murphy J P; Kirschmeier P; Weinstein I B
Overproduction of protein kinase C causes disordered growth control in rat fibroblasts.
Cell 1988;52(3):343-54.
1988: Ronai Z A; Okin E; Weinstein I B
Ultraviolet light induces the expression of oncogenes in rat fibroblast and human keratinocyte cells.
Oncogene 1988;2(2):201-4.
1988: Hsieh L L; Peraino C; Weinstein I B
Expression of endogenous retrovirus-like sequences and cellular oncogenes during phenobarbital treatment and regeneration in rat liver.
Cancer research 1988;48(2):265-9.
1988: Perera F P; Santella R M; Brenner D; Young T L; Weinstein I B
Application of biological markers to the study of lung cancer causation and prevention.
IARC scientific publications 1988;(89):451-9.
1988: Housey G M; Johnson M D; Hsiao W L; O'Brian C A; Weinstein I B
Structural and functional studies of protein kinase C.
Advances in experimental medicine and biology 1988;234():127-40.
1988: Begemann M; Hsiao W L; Weinstein I B
Differences between normal and transformed murine fibroblasts in the expression of various promoter/enhancer-chloramphenicol acetyltransferase constructs.
Molecular carcinogenesis 1988;1(3):196-201.
1987: O'Brian C A; Housey G M; Weinstein I B
Binding of protein kinase C to napthalenesulfonamide- and phenothiazine-agarose columns: evidence for direct interactions between protein kinase C and cationic amphiphilic inhibitors of the enzyme.
Biochemical pharmacology 1987;36(23):4179-81.
1987: Guillem J G; O'Brian C A; Fitzer C J; Johnson M D; Forde K A; LoGerfo P; Weinstein I B
Studies on protein kinase C and colon carcinogenesis.
Archives of surgery (Chicago, Ill. : 1960) 1987;122(12):1475-8.
1987: Johnson M D; Housey G M; O'Brian C A; Kirschmeier P T; Weinstein I B
Role of protein kinase C in regulation of gene expression and relevance to tumor promotion.
Environmental health perspectives 1987;76():89-95.
1987: Hsiao W L; Lopez C A; Wu T; Weinstein I B
A factor present in fetal calf serum enhances oncogene-induced transformation of rodent fibroblasts.
Molecular and cellular biology 1987;7(10):3380-5.
1987: Johnson M D; Housey G M; Kirschmeier P T; Weinstein I B
Molecular cloning of gene sequences regulated by tumor promoters and mitogens through protein kinase C.
Molecular and cellular biology 1987;7(8):2821-9.
1987: Hsieh L L; Hsiao W L; Peraino C; Maronpot R R; Weinstein I B
Expression of retroviral sequences and oncogenes in rat liver tumors induced by diethylnitrosamine.
Cancer research 1987;47(13):3421-4.
1987: Guillem J G; O'Brian C A; Fitzer C J; Forde K A; LoGerfo P; Treat M; Weinstein I B
Altered levels of protein kinase C and Ca2+-dependent protein kinases in human colon carcinomas.
Cancer research 1987;47(8):2036-9.
1987: Fitzer C J; O'Brian C A; Guillem J G; Weinstein I B
The regulation of protein kinase C by chenodeoxycholate, deoxycholate and several structurally related bile acids.
Carcinogenesis 1987;8(2):217-20.
1987: Housey G M; O'Brian C A; Johnson M D; Kirschmeier P; Weinstein I B
Isolation of cDNA clones encoding protein kinase C: evidence for a protein kinase C-related gene family.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(4):1065-9.
1986: Weinstein I B; O'Brian C A; Housey G M; Johnson M D; Kirschmeier P; Hsiao W
Studies on the mechanism of action of protein kinase C and the isolation of molecular clones encoding the enzyme.
Symposium on Fundamental Cancer Research 1986;39():173-83.
1985: Housey G M; Kirschmeier P; Garte S J; Burns F; Troll W; Weinstein I B
Expression of long terminal repeat (LTR) sequences in carcinogen-induced murine skin carcinomas.
Biochemical and biophysical research communications 1985;127(1):391-8.
1983: Perkins A S; Kirschmeier P T; Gattoni-Celli S; Weinstein I B
Design of a retrovirus-derived vector for expression and transduction of exogenous genes in mammalian cells.
Molecular and cellular biology 1983;3(6):1123-32.
1981: Fisher P B; Young C S; Weinstein I B; Carter T H
Tumor promoters alter the temporal program of adenovirus replication in human cells.
Molecular and cellular biology 1981;1(4):370-80.
1980: Lee L S; Weinstein I B
Studies on the mechanism by which a tumor promoter inhibits binding of epidermal growth factor to cellular receptors.
Carcinogenesis 1980;1(8):669-79.

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