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John Weinstein

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Oligonucleotide Array Sequence Analysis

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Publications

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Orina Josiah N; Calcagno Anna Maria; Wu Chung-Pu; Varma Sudhir; Shih Joanna; Lin Min; Eichler Gabriel; Weinstein John N; Pommier Yves; Ambudkar Suresh V; Gottesman Michael M; Gillet Jean-Pierre
Evaluation of current methods used to analyze the expression profiles of ATP-binding cassette transporters yields an improved drug-discovery database.
Kohn Kurt W; Aladjem Mirit I; Weinstein John N; Pommier Yves
Network architecture of signaling from uncoupled helicase-polymerase to cell cycle checkpoints and trans-lesion DNA synthesis.
Lorenzi Philip L; Weinstein John N
Asparagine synthetase: a new potential biomarker in ovarian cancer.

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All Publications

2009: Orina Josiah N; Calcagno Anna Maria; Wu Chung-Pu; Varma Sudhir; Shih Joanna; Lin Min; Eichler Gabriel; Weinstein John N; Pommier Yves; Ambudkar Suresh V; Gottesman Michael M; Gillet Jean-Pierre
Evaluation of current methods used to analyze the expression profiles of ATP-binding cassette transporters yields an improved drug-discovery database.
Molecular cancer therapeutics 2009;8(7):2057-66.
2009: Kohn Kurt W; Aladjem Mirit I; Weinstein John N; Pommier Yves
Network architecture of signaling from uncoupled helicase-polymerase to cell cycle checkpoints and trans-lesion DNA synthesis.
Cell cycle (Georgetown, Tex.) 2009;8(14):2281-99.
2009: Lorenzi Philip L; Weinstein John N
Asparagine synthetase: a new potential biomarker in ovarian cancer.
Drug news & perspectives 2009;22(1):61-4.
2009: Shankavaram Uma T; Varma Sudhir; Kane David; Sunshine Margot; Chary Krishna K; Reinhold William C; Pommier Yves; Weinstein John N
CellMiner: a relational database and query tool for the NCI-60 cancer cell lines.
BMC genomics 2009;10():277.
2008: Roschke Anna V; Glebov Oleg K; Lababidi Samir; Gehlhaus Kristen S; Weinstein John N; Kirsch Ilan R
Chromosomal instability is associated with higher expression of genes implicated in epithelial-mesenchymal transition, cancer invasiveness, and metastasis and with lower expression of genes involved in cell cycle checkpoints, DNA repair, and chromatin maintenance.
Neoplasia (New York, N.Y.) 2008;10(11):1222-30.
2008: Lorenzi Philip L; Llamas Jenny; Gunsior Michele; Ozbun Laurent; Reinhold William C; Varma Sudhir; Ji Helen; Kim Hijoo; Hutchinson Amy A; Kohn Elise C; Goldsmith Paul K; Birrer Michael J; Weinstein John N
Asparagine synthetase is a predictive biomarker of L-asparaginase activity in ovarian cancer cell lines.
Molecular cancer therapeutics 2008;7(10):3123-8.
2008: Okabe Mitsunori; Szakács Gergely; Reimers Mark A; Suzuki Toshihiro; Hall Matthew D; Abe Takaaki; Weinstein John N; Gottesman Michael M
Profiling SLCO and SLC22 genes in the NCI-60 cancer cell lines to identify drug uptake transporters.
Molecular cancer therapeutics 2008;7(9):3081-91.
2008: Ruden Douglas M; Jamison D Curtis; Zeeberg Barry R; Garfinkel Mark D; Weinstein John N; Rasouli Parsa; Lu Xiangyi
The EDGE hypothesis: epigenetically directed genetic errors in repeat-containing proteins (RCPs) involved in evolution, neuroendocrine signaling, and cancer.
Frontiers in neuroendocrinology 2008;29(3):428-44.
2008: Boersma Brenda J; Reimers Mark; Yi Ming; Ludwig Joseph A; Luke Brian T; Stephens Robert M; Yfantis Harry G; Lee Dong H; Weinstein John N; Ambs Stefan
A stromal gene signature associated with inflammatory breast cancer.
International journal of cancer. Journal international du cancer 2008;122(6):1324-32.
2008: Patterson Andrew D; Li Henghong; Eichler Gabriel S; Krausz Kristopher W; Weinstein John N; Fornace Albert J; Gonzalez Frank J; Idle Jeffrey R
UPLC-ESI-TOFMS-based metabolomics and gene expression dynamics inspector self-organizing metabolomic maps as tools for understanding the cellular response to ionizing radiation.
Analytical chemistry 2008;80(3):665-74.
2008: Amundson Sally A; Do Khanh T; Vinikoor Lisa C; Lee R Anthony; Koch-Paiz Christine A; Ahn Jaeyong; Reimers Mark; Chen Yidong; Scudiero Dominic A; Weinstein John N; Trent Jeffrey M; Bittner Michael L; Meltzer Paul S; Fornace Albert J
Integrating global gene expression and radiation survival parameters across the 60 cell lines of the National Cancer Institute Anticancer Drug Screen.
Cancer research 2008;68(2):415-24.
2008: Stevens Ellen V; Nishizuka Satoshi; Antony Smitha; Reimers Mark; Varma Sudhir; Young Lynn; Munson Peter J; Weinstein John N; Kohn Elise C; Pommier Yves
Predicting cisplatin and trabectedin drug sensitivity in ovarian and colon cancers.
Molecular cancer therapeutics 2008;7(1):10-8.
2008: Blower Paul E; Chung Ji-Hyun; Verducci Joseph S; Lin Shili; Park Jong-Kook; Dai Zunyan; Liu Chang-Gong; Schmittgen Thomas D; Reinhold William C; Croce Carlo M; Weinstein John N; Sadee Wolfgang
MicroRNAs modulate the chemosensitivity of tumor cells.
Molecular cancer therapeutics 2008;7(1):1-9.
2008: Kohn Kurt W; Aladjem Mirit I; Weinstein John N; Pommier Yves
Chromatin challenges during DNA replication: a systems representation.
Molecular biology of the cell 2008;19(1):1-7.
2008: Sheehan K M; Gulmann C; Eichler G S; Weinstein J N; Barrett H L; Kay E W; Conroy R M; Liotta L A; Petricoin E F
Signal pathway profiling of epithelial and stromal compartments of colonic carcinoma reveals epithelial-mesenchymal transition.
Oncogene 2008;27(3):323-31.
2008: Ryan Michael C; Zeeberg Barry R; Caplen Natasha J; Cleland James A; Kahn Ari B; Liu Hongfang; Weinstein John N
SpliceCenter: a suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi, microarray, and peptide-based studies.
BMC bioinformatics 2008;9():313.
2008: Kestler Hans A; Müller André; Kraus Johann M; Buchholz Malte; Gress Thomas M; Liu Hongfang; Kane David W; Zeeberg Barry R; Weinstein John N
VennMaster: area-proportional Euler diagrams for functional GO analysis of microarrays.
BMC bioinformatics 2008;9():67.
2007: Miao Ze-Hong; Player Audrey; Shankavaram Uma; Wang Yong-Hong; Zimonjic Drazen B; Lorenzi Philip L; Liao Zhi-Yong; Liu Hong; Shimura Tsutomu; Zhang Hong-Liang; Meng Ling-Hua; Zhang Yong-Wei; Kawasaki Ernest S; Popescu Nicholas C; Aladjem Mirit I; Goldstein David J; Weinstein John N; Pommier Yves
Nonclassic functions of human topoisomerase I: genome-wide and pharmacologic analyses.
Cancer research 2007;67(18):8752-61.
2007: Liu Hongfang; Zeeberg Barry R; Qu Gang; Koru A Gunes; Ferrucci Alessandro; Kahn Ari; Ryan Michael C; Nuhanovic Antej; Munson Peter J; Reinhold William C; Kane David W; Weinstein John N
AffyProbeMiner: a web resource for computing or retrieving accurately redefined Affymetrix probe sets.
Bioinformatics (Oxford, England) 2007;23(18):2385-90.
2007: Lee Jae K; Havaleshko Dmytro M; Cho Hyungjun; Weinstein John N; Kaldjian Eric P; Karpovich John; Grimshaw Andrew; Theodorescu Dan
A strategy for predicting the chemosensitivity of human cancers and its application to drug discovery.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(32):13086-91.
2007: Blower Paul E; Verducci Joseph S; Lin Shili; Zhou Jin; Chung Ji-Hyun; Dai Zunyan; Liu Chang-Gong; Reinhold William; Lorenzi Philip L; Kaldjian Eric P; Croce Carlo M; Weinstein John N; Sadee Wolfgang
MicroRNA expression profiles for the NCI-60 cancer cell panel.
Molecular cancer therapeutics 2007;6(5):1483-91.
2007: Shankavaram Uma T; Reinhold William C; Nishizuka Satoshi; Major Sylvia; Morita Daisaku; Chary Krishna K; Reimers Mark A; Scherf Uwe; Kahn Ari; Dolginow Douglas; Cossman Jeffrey; Kaldjian Eric P; Scudiero Dominic A; Petricoin Emanuel; Liotta Lance; Lee Jae K; Weinstein John N
Transcript and protein expression profiles of the NCI-60 cancer cell panel: an integromic microarray study.
Molecular cancer therapeutics 2007;6(3):820-32.
2007: Reinhold William C; Reimers Mark A; Maunakea Alika K; Kim Sohyoung; Lababidi Samir; Scherf Uwe; Shankavaram Uma T; Ziegler Micah S; Stewart Claudia; Kouros-Mehr Hosein; Cui Hengmi; Dolginow Douglas; Scudiero Dominic A; Pommier Yves G; Munroe David J; Feinberg Andrew P; Weinstein John N
Detailed DNA methylation profiles of the E-cadherin promoter in the NCI-60 cancer cells.
Molecular cancer therapeutics 2007;6(2):391-403.
2007: Eichler Gabriel S; Reimers Mark; Kane David; Weinstein John N
The LeFE algorithm: embracing the complexity of gene expression in the interpretation of microarray data.
Genome biology 2007;8(9):R187.
2007: Martin Scott E; Jones Tamara L; Thomas Cheryl L; Lorenzi Philip L; Nguyen Dac A; Runfola Timothy; Gunsior Michele; Weinstein John N; Goldsmith Paul K; Lader Eric; Huppi Konrad; Caplen Natasha J
Multiplexing siRNAs to compress RNAi-based screen size in human cells.
Nucleic acids research 2007;35(8):e57.
2007: Kahn Ari B; Ryan Michael C; Liu Hongfang; Zeeberg Barry R; Jamison D Curtis; Weinstein John N
SpliceMiner: a high-throughput database implementation of the NCBI Evidence Viewer for microarray splice variant analysis.
BMC bioinformatics 2007;8():75.
2006: Lorenzi Philip L; Reinhold William C; Rudelius Martina; Gunsior Michele; Shankavaram Uma; Bussey Kimberly J; Scherf Uwe; Eichler Gabriel S; Martin Scott E; Chin Koei; Gray Joe W; Kohn Elise C; Horak Ivan D; Von Hoff Daniel D; Raffeld Mark; Goldsmith Paul K; Caplen Natasha J; Weinstein John N
Asparagine synthetase as a causal, predictive biomarker for L-asparaginase activity in ovarian cancer cells.
Molecular cancer therapeutics 2006;5(11):2613-23.
2006: Weinstein John N
Spotlight on molecular profiling: "Integromic" analysis of the NCI-60 cancer cell lines.
Molecular cancer therapeutics 2006;5(11):2601-5.
2006: Riss Joseph; Khanna Chand; Koo Seongjoon; Chandramouli Gadisetti V R; Yang Howard H; Hu Ying; Kleiner David E; Rosenwald Andreas; Schaefer Carl F; Ben-Sasson Shmuel A; Yang Liming; Powell John; Kane David W; Star Robert A; Aprelikova Olga; Bauer Kristin; Vasselli James R; Maranchie Jodi K; Kohn Kurt W; Buetow Ken H; Linehan W Marston; Weinstein John N; Lee Maxwell P; Klausner Richard D; Barrett J Carl
Cancers as wounds that do not heal: differences and similarities between renal regeneration/repair and renal cell carcinoma.
Cancer research 2006;66(14):7216-24.
2006: Pommier Yves; Weinstein John N; Aladjem Mirit I; Kohn Kurt W
Chk2 molecular interaction map and rationale for Chk2 inhibitors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(9):2657-61.
2006: Ludwig Joseph A; Szakács Gergely; Martin Scott E; Chu Benjamin F; Cardarelli Carol; Sauna Zuben E; Caplen Natasha J; Fales Henry M; Ambudkar Suresh V; Weinstein John N; Gottesman Michael M
Selective toxicity of NSC73306 in MDR1-positive cells as a new strategy to circumvent multidrug resistance in cancer.
Cancer research 2006;66(9):4808-15.
2006: Bussey Kimberly J; Chin Koei; Lababidi Samir; Reimers Mark; Reinhold William C; Kuo Wen-Lin; Gwadry Fuad; Ajay; Kouros-Mehr Hosein; Fridlyand Jane; Jain Ajay; Collins Colin; Nishizuka Satoshi; Tonon Giovanni; Roschke Anna; Gehlhaus Kristen; Kirsch Ilan; Scudiero Dominic A; Gray Joe W; Weinstein John N
Integrating data on DNA copy number with gene expression levels and drug sensitivities in the NCI-60 cell line panel.
Molecular cancer therapeutics 2006;5(4):853-67.
2006: Blower Paul E; Cross Kevin P; Eichler Gabriel S; Myatt Glenn J; Weinstein John N; Yang Chihae
Comparison of methods for sequential screening of large compound sets.
Combinatorial chemistry & high throughput screening 2006;9(2):115-22.
2006: Kohn Kurt W; Aladjem Mirit I; Weinstein John N; Pommier Yves
Molecular interaction maps of bioregulatory networks: a general rubric for systems biology.
Molecular biology of the cell 2006;17(1):1-13.
2006: Kohn Kurt W; Aladjem Mirit I; Kim Sohyoung; Weinstein John N; Pommier Yves
Depicting combinatorial complexity with the molecular interaction map notation.
Molecular systems biology 2006;2():51.
2006: Major Sylvia M; Nishizuka Satoshi; Morita Daisaku; Rowland Rick; Sunshine Margot; Shankavaram Uma; Washburn Frank; Asin Daniel; Kouros-Mehr Hosein; Kane David; Weinstein John N
AbMiner: a bioinformatic resource on available monoclonal antibodies and corresponding gene identifiers for genomic, proteomic, and immunologic studies.
BMC bioinformatics 2006;7():192.
2005: Staib Frank; Robles Ana I; Varticovski Lyuba; Wang Xin W; Zeeberg Barry R; Sirotin Michail; Zhurkin Victor B; Hofseth Lorne J; Hussain S Perwez; Weinstein John N; Galle Peter R; Harris Curtis C
The p53 tumor suppressor network is a key responder to microenvironmental components of chronic inflammatory stress.
Cancer research 2005;65(22):10255-64.
2005: Ludwig Joseph A; Weinstein John N
Biomarkers in cancer staging, prognosis and treatment selection.
Nature reviews. Cancer 2005;5(11):845-56.
2005: Ule Jernej; Ule Aljaz; Spencer Joanna; Williams Alan; Hu Jing-Shan; Cline Melissa; Wang Hui; Clark Tyson; Fraser Claire; Ruggiu Matteo; Zeeberg Barry R; Kane David; Weinstein John N; Blume John; Darnell Robert B
Nova regulates brain-specific splicing to shape the synapse.
Nature genetics 2005;37(8):844-52.
2005: Roschke Anna V; Lababidi Samir; Tonon Giovanni; Gehlhaus Kristen S; Bussey Kimberly; Weinstein John N; Kirsch Ilan R
Karyotypic "state" as a potential determinant for anticancer drug discovery.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(8):2964-9.
2005: Zeeberg Barry R; Qin Haiying; Narasimhan Sudarshan; Sunshine Margot; Cao Hong; Kane David W; Reimers Mark; Stephens Robert M; Bryant David; Burt Stanley K; Elnekave Eldad; Hari Danielle M; Wynn Thomas A; Cunningham-Rundles Charlotte; Stewart Donn M; Nelson David; Weinstein John N
High-Throughput GoMiner, an 'industrial-strength' integrative gene ontology tool for interpretation of multiple-microarray experiments, with application to studies of Common Variable Immune Deficiency (CVID).
BMC bioinformatics 2005;6():168.
2005: Reimers Mark; Weinstein John N
Quality assessment of microarrays: visualization of spatial artifacts and quantitation of regional biases.
BMC bioinformatics 2005;6():166.
2004: Annereau Jean-Philippe; Szakács Gergely; Tucker Charles J; Arciello Angela; Cardarelli Carol; Collins Jennifer; Grissom Sherry; Zeeberg Barry R; Reinhold William; Weinstein John N; Pommier Yves; Paules Richard S; Gottesman Michael M
Analysis of ATP-binding cassette transporter expression in drug-selected cell lines by a microarray dedicated to multidrug resistance.
Molecular pharmacology 2004;66(6):1397-405.
2004: Szakács Gergely; Annereau Jean-Philippe; Lababidi Samir; Shankavaram Uma; Arciello Angela; Bussey Kimberly J; Reinhold William; Guo Yanping; Kruh Gary D; Reimers Mark; Weinstein John N; Gottesman Michael M
Predicting drug sensitivity and resistance: profiling ABC transporter genes in cancer cells.
Cancer cell 2004;6(2):129-37.
2004: Kohn Kurt W; Riss Joseph; Aprelikova Olga; Weinstein John N; Pommier Yves; Barrett J Carl
Properties of switch-like bioregulatory networks studied by simulation of the hypoxia response control system.
Molecular biology of the cell 2004;15(7):3042-52.
2004: Zeeberg Barry R; Riss Joseph; Kane David W; Bussey Kimberly J; Uchio Edward; Linehan W Marston; Barrett J Carl; Weinstein John N
Mistaken identifiers: gene name errors can be introduced inadvertently when using Excel in bioinformatics.
BMC bioinformatics 2004;5():80.
2004: Huang Ying; Anderle Pascale; Bussey Kimberly J; Barbacioru Catalin; Shankavaram Uma; Dai Zunyan; Reinhold William C; Papp Audrey; Weinstein John N; Sadée Wolfgang
Membrane transporters and channels: role of the transportome in cancer chemosensitivity and chemoresistance.
Cancer research 2004;64(12):4294-301.
2004: Aladjem Mirit I; Pasa Stefania; Parodi Silvio; Weinstein John N; Pommier Yves; Kohn Kurt W
Molecular interaction maps--a diagrammatic graphical language for bioregulatory networks.
Science's STKE : signal transduction knowledge environment 2004;2004(222):pe8.
2004: Weinstein John N
Integromic analysis of the NCI-60 cancer cell lines.
Breast disease 2004;19():11-22.
2003: Roschke Anna V; Tonon Giovanni; Gehlhaus Kristen S; McTyre Nicolas; Bussey Kimberly J; Lababidi Samir; Scudiero Dominic A; Weinstein John N; Kirsch Ilan R
Karyotypic complexity of the NCI-60 drug-screening panel.
Cancer research 2003;63(24):8634-47.
2003: Nishizuka Satoshi; Charboneau Lu; Young Lynn; Major Sylvia; Reinhold William C; Waltham Mark; Kouros-Mehr Hosein; Bussey Kimberly J; Lee Jae K; Espina Virginia; Munson Peter J; Petricoin Emanuel; Liotta Lance A; Weinstein John N
Proteomic profiling of the NCI-60 cancer cell lines using new high-density reverse-phase lysate microarrays.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(24):14229-34.
2003: Weinstein John N; Pommier Yves
Transcriptomic analysis of the NCI-60 cancer cell lines.
Comptes rendus biologies 2003;326(10-11):909-20.
2003: Nishizuka Satoshi; Chen Sing-Tsung; Gwadry Fuad G; Alexander Jes; Major Sylvia M; Scherf Uwe; Reinhold William C; Waltham Mark; Charboneau Lu; Young Lynn; Bussey Kimberly J; Kim Sohyoung; Lababidi Samir; Lee Jae K; Pittaluga Stefania; Scudiero Dominic A; Sausville Edward A; Munson Peter J; Petricoin Emmanuel F; Liotta Lance A; Hewitt Stephen M; Raffeld Mark; Weinstein John N
Diagnostic markers that distinguish colon and ovarian adenocarcinomas: identification by genomic, proteomic, and tissue array profiling.
Cancer research 2003;63(17):5243-50.
2003: Yoshida Akira; Urasaki Yoshimasa; Waltham Mark; Bergman Ann-Charlotte; Pourquier Philippe; Rothwell Dominic G; Inuzuka Manabu; Weinstein John N; Ueda Takanori; Appella Ettore; Hickson Ian D; Pommier Yves
Human apurinic/apyrimidinic endonuclease (Ape1) and its N-terminal truncated form (AN34) are involved in DNA fragmentation during apoptosis.
The Journal of biological chemistry 2003;278(39):37768-76.
2003: Daoud Sayed S; Munson Peter J; Reinhold William; Young Lynn; Prabhu Vinay V; Yu Qiang; LaRose Jihyun; Kohn Kurt W; Weinstein John N; Pommier Yves
Impact of p53 knockout and topotecan treatment on gene expression profiles in human colon carcinoma cells: a pharmacogenomic study.
Cancer research 2003;63(11):2782-93.
2003: Reinhold William C; Kouros-Mehr Hosein; Kohn Kurt W; Maunakea Alika K; Lababidi Samir; Roschke Anna; Stover Kristen; Alexander Jes; Pantazis Panayotis; Miller Lance; Liu Edison; Kirsch Ilan R; Urasaki Yoshimasa; Pommier Yves; Weinstein John N
Apoptotic susceptibility of cancer cells selected for camptothecin resistance: gene expression profiling, functional analysis, and molecular interaction mapping.
Cancer research 2003;63(5):1000-11.
2003: Feng Weimin; Wang Geoffrey; Zeeberg Barry R; Guo Kejiao; Fojo Anthony T; Kane David W; Reinhold William C; Lababidi Samir; Weinstein John N; Wang May D
Development of gene ontology tool for biological interpretation of genomic and proteomic data.
AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium 2003;():839.
2003: Lee Jae K; Bussey Kimberly J; Gwadry Fuad G; Reinhold William; Riddick Gregory; Pelletier Sandra L; Nishizuka Satoshi; Szakacs Gergely; Annereau Jean-Phillipe; Shankavaram Uma; Lababidi Samir; Smith Lawrence H; Gottesman Michael M; Weinstein John N
Comparing cDNA and oligonucleotide array data: concordance of gene expression across platforms for the NCI-60 cancer cells.
Genome biology 2003;4(12):R82.
2003: Zeeberg Barry R; Feng Weimin; Wang Geoffrey; Wang May D; Fojo Anthony T; Sunshine Margot; Narasimhan Sudarshan; Kane David W; Reinhold William C; Lababidi Samir; Bussey Kimberly J; Riss Joseph; Barrett J Carl; Weinstein John N
GoMiner: a resource for biological interpretation of genomic and proteomic data.
Genome biology 2003;4(4):R28.
2003: Bussey Kimberly J; Kane David; Sunshine Margot; Narasimhan Sudar; Nishizuka Satoshi; Reinhold William C; Zeeberg Barry; Ajay Weinstein; Weinstein John N
MatchMiner: a tool for batch navigation among gene and gene product identifiers.
Genome biology 2003;4(4):R27.
2002: Weinstein John N
'Omic' and hypothesis-driven research in the molecular pharmacology of cancer.
Current opinion in pharmacology 2002;2(4):361-5.
2002: Zhou Yi; Gwadry Fuad G; Reinhold William C; Miller Lance D; Smith Lawrence H; Scherf Uwe; Liu Edison T; Kohn Kurt W; Pommier Yves; Weinstein John N
Transcriptional regulation of mitotic genes by camptothecin-induced DNA damage: microarray analysis of dose- and time-dependent effects.
Cancer research 2002;62(6):1688-95.
2002: Weinstein John N; Scherf Uwe; Lee Jae K; Nishizuka Satoshi; Gwadry Fuad; Bussey Ajay Kim; Kim S; Smith Lawrence H; Tanabe Lorraine; Richman Samuel; Alexander Jessie; Kouros-Mehr Hosein; Maunakea Alika; Reinhold William C
The bioinformatics of microarray gene expression profiling.
Cytometry 2002;47(1):46-9.
2002: Blower P E; Yang C; Fligner M A; Verducci J S; Yu L; Richman S; Weinstein J N
Pharmacogenomic analysis: correlating molecular substructure classes with microarray gene expression data.
The pharmacogenomics journal 2002;2(4):259-71.
2001: Fan Y; Shi L M; Kohn K W; Pommier Y; Weinstein J N
Quantitative structure-antitumor activity relationships of camptothecin analogues: cluster analysis and genetic algorithm-based studies.
Journal of medicinal chemistry 2001;44(20):3254-63.
2001: Viswanadhan V N; Mueller G A; Basak S C; Weinstein J N
Comparison of a neural net-based QSAR algorithm (PCANN) with Hologram- and multiple linear regression-based QSAR approaches: application to 1,4-dihydropyridine-based calcium channel antagonists.
Journal of chemical information and computer sciences 2001;41(3):505-11.
2000: Weinstein J N; Buolamwini J K
Molecular targets in cancer drug discovery: cell-based profiling.
Current pharmaceutical design 2000;6(4):473-83.
2000: Shi L M; Fan Y; Lee J K; Waltham M; Andrews D T; Scherf U; Paull K D; Weinstein J N
Mining and visualizing large anticancer drug discovery databases.
Journal of chemical information and computer sciences 2000;40(2):367-79.
2000: Scherf U; Ross D T; Waltham M; Smith L H; Lee J K; Tanabe L; Kohn K W; Reinhold W C; Myers T G; Andrews D T; Scudiero D A; Eisen M B; Sausville E A; Pommier Y; Botstein D; Brown P O; Weinstein J N
A gene expression database for the molecular pharmacology of cancer.
Nature genetics 2000;24(3):236-44.
2000: Ross D T; Scherf U; Eisen M B; Perou C M; Rees C; Spellman P; Iyer V; Jeffrey S S; Van de Rijn M; Waltham M; Pergamenschikov A; Lee J C; Lashkari D; Shalon D; Myers T G; Weinstein J N; Botstein D; Brown P O
Systematic variation in gene expression patterns in human cancer cell lines.
Nature genetics 2000;24(3):227-35.
2000: Rindflesch T C; Tanabe L; Weinstein J N; Hunter L
EDGAR: extraction of drugs, genes and relations from the biomedical literature.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 2000;():517-28.
1999: Tanabe L; Scherf U; Smith L H; Lee J K; Hunter L; Weinstein J N
MedMiner: an Internet text-mining tool for biomedical information, with application to gene expression profiling.
BioTechniques 1999;27(6):1210-4, 1216-7.
1999: Carrier F; Georgel P T; Pourquier P; Blake M; Kontny H U; Antinore M J; Gariboldi M; Myers T G; Weinstein J N; Pommier Y; Fornace A J
Gadd45, a p53-responsive stress protein, modifies DNA accessibility on damaged chromatin.
Molecular and cellular biology 1999;19(3):1673-85.
1998: Fan Y; Weinstein J N; Kohn K W; Shi L M; Pommier Y
Molecular modeling studies of the DNA-topoisomerase I ternary cleavable complex with camptothecin.
Journal of medicinal chemistry 1998;41(13):2216-26.
1998: Shi L M; Fan Y; Myers T G; O'Connor P M; Paull K D; Friend S H; Weinstein J N
Mining the NCI anticancer drug discovery databases: genetic function approximation for the QSAR study of anticancer ellipticine analogues.
Journal of chemical information and computer sciences 1998;38(2):189-99.
1998: Shi L M; Myers T G; Fan Y; O'Connor P M; Paull K D; Friend S H; Weinstein J N
Mining the National Cancer Institute Anticancer Drug Discovery Database: cluster analysis of ellipticine analogs with p53-inverse and central nervous system-selective patterns of activity.
Molecular pharmacology 1998;53(2):241-51.
1997: Wosikowski K; Schuurhuis D; Johnson K; Paull K D; Myers T G; Weinstein J N; Bates S E
Identification of epidermal growth factor receptor and c-erbB2 pathway inhibitors by correlation with gene expression patterns.
Journal of the National Cancer Institute 1997;89(20):1505-15.
1997: O'Connor P M; Jackman J; Bae I; Myers T G; Fan S; Mutoh M; Scudiero D A; Monks A; Sausville E A; Weinstein J N; Friend S; Fornace A J; Kohn K W
Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents.
Cancer research 1997;57(19):4285-300.
1997: Myers T G; Anderson N L; Waltham M; Li G; Buolamwini J K; Scudiero D A; Paull K D; Sausville E A; Weinstein J N
A protein expression database for the molecular pharmacology of cancer.
Electrophoresis 1997;18(3-4):647-53.
1997: Li G; Waltham M; Anderson N L; Unsworth E; Treston A; Weinstein J N
Rapid mass spectrometric identification of proteins from two-dimensional polyacrylamide gels after in gel proteolytic digestion.
Electrophoresis 1997;18(3-4):391-402.
1996: Viswanadhan V N; Reddy M R; Wlodawer A; Varney M D; Weinstein J N
An approach to rapid estimation of relative binding affinities of enzyme inhibitors: application to peptidomimetic inhibitors of the human immunodeficiency virus type 1 protease.
Journal of medicinal chemistry 1996;39(3):705-12.
1995: Chokekijchai S; Shirasaka T; Weinstein J N; Mitsuya H
In vitro anti-HIV-1 activity of HIV protease inhibitor KNI-272 in resting and activated cells: implications for its combined use with AZT or ddI.
Antiviral research 1995;28(1):25-38.
1995: Saga T; Neumann R D; Heya T; Sato J; Kinuya S; Le N; Paik C H; Weinstein J N
Targeting cancer micrometastases with monoclonal antibodies: a binding-site barrier.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(19):8999-9003.
1995: Raghavan K; Buolamwini J K; Fesen M R; Pommier Y; Kohn K W; Weinstein J N
Three-dimensional quantitative structure-activity relationship (QSAR) of HIV integrase inhibitors: a comparative molecular field analysis (CoMFA) study.
Journal of medicinal chemistry 1995;38(6):890-7.
1995: Bates S E; Fojo A T; Weinstein J N; Myers T G; Alvarez M; Pauli K D; Chabner B A
Molecular targets in the National Cancer Institute drug screen.
Journal of cancer research and clinical oncology 1995;121(9-10):495-500.
1994: van Osdol W W; Myers T G; Paull K D; Kohn K W; Weinstein J N
Use of the Kohonen self-organizing map to study the mechanisms of action of chemotherapeutic agents.
Journal of the National Cancer Institute 1994;86(24):1853-9.
1994: Casciari J J; Hollingshead M G; Alley M C; Mayo J G; Malspeis L; Miyauchi S; Grever M R; Weinstein J N
Growth and chemotherapeutic response of cells in a hollow-fiber in vitro solid tumor model.
Journal of the National Cancer Institute 1994;86(24):1846-52.
1994: Lori F; Malykh A; Cara A; Sun D; Weinstein J N; Lisziewicz J; Gallo R C
Hydroxyurea as an inhibitor of human immunodeficiency virus-type 1 replication.
Science (New York, N.Y.) 1994;266(5186):801-5.
1994: Sung C; van Osdol W W; Saga T; Neumann R D; Dedrick R L; Weinstein J N
Streptavidin distribution in metastatic tumors pretargeted with a biotinylated monoclonal antibody: theoretical and experimental pharmacokinetics.
Cancer research 1994;54(8):2166-75.
1994: Saga T; Weinstein J N; Jeong J M; Heya T; Lee J T; Le N; Paik C H; Sung C; Neumann R D
Two-step targeting of experimental lung metastases with biotinylated antibody and radiolabeled streptavidin.
Cancer research 1994;54(8):2160-5.
1994: Koutsoukos A D; Rubinstein L V; Faraggi D; Simon R M; Kalyandrug S; Weinstein J N; Kohn K W; Paull K D
Discrimination techniques applied to the NCI in vitro anti-tumour drug screen: predicting biochemical mechanism of action.
Statistics in medicine 1994;13(5-7):719-30.
1994: Weinstein J N; Myers T; Buolamwini J; Raghavan K; van Osdol W; Licht J; Viswanadhan V N; Kohn K W; Rubinstein L V; Koutsoukos A D
Predictive statistics and artificial intelligence in the U.S. National Cancer Institute's Drug Discovery Program for Cancer and AIDS.
Stem cells (Dayton, Ohio) 1994;12(1):13-22.
1993: van Osdol W W; Sung C; Dedrick R L; Weinstein J N
A distributed pharmacokinetic model of two-step imaging and treatment protocols: application to streptavidin-conjugated monoclonal antibodies and radiolabeled biotin.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1993;34(9):1552-64.
1993: Juweid M; Sato J; Paik C; Onay-Basaran S; Weinstein J N; Neumann R D
A simple method for affinity purification of radiolabeled monoclonal antibodies.
Nuclear medicine and biology 1993;20(3):311-5.
1993: Betageri G V; Black C D; Szebeni J; Wahl L M; Weinstein J N
Fc-receptor-mediated targeting of antibody-bearing liposomes containing dideoxycytidine triphosphate to human monocyte/macrophages.
The Journal of pharmacy and pharmacology 1993;45(1):48-53.
1992: Weinstein J N; Kohn K W; Grever M R; Viswanadhan V N; Rubinstein L V; Monks A P; Scudiero D A; Welch L; Koutsoukos A D; Chiausa A J
Neural computing in cancer drug development: predicting mechanism of action.
Science (New York, N.Y.) 1992;258(5081):447-51.
1992: Juweid M; Neumann R; Paik C; Perez-Bacete M J; Sato J; van Osdol W; Weinstein J N
Micropharmacology of monoclonal antibodies in solid tumors: direct experimental evidence for a binding site barrier.
Cancer research 1992;52(19):5144-53.
1992: Weinstein J N; van Osdol W
Early intervention in cancer using monoclonal antibodies and other biological ligands: micropharmacology and the "binding site barrier".
Cancer research 1992;52(9 Suppl):2747s-2751s.
1992: Kageyama S; Weinstein J N; Shirasaka T; Kempf D J; Norbeck D W; Plattner J J; Erickson J; Mitsuya H
In vitro inhibition of human immunodeficiency virus (HIV) type 1 replication by C2 symmetry-based HIV protease inhibitors as single agents or in combinations.
Antimicrobial agents and chemotherapy 1992;36(5):926-33.
1992: Weinstein J N; van Osdol W
The macroscopic and microscopic pharmacology of monoclonal antibodies.
International journal of immunopharmacology 1992;14(3):457-63.
1991: Reddy M R; Viswanadhan V N; Weinstein J N
Relative differences in the binding free energies of human immunodeficiency virus 1 protease inhibitors: a thermodynamic cycle-perturbation approach.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(22):10287-91.
1991: Viswanadhan V N; Denckla B; Weinstein J N
New joint prediction algorithm (Q7-JASEP) improves the prediction of protein secondary structure.
Biochemistry 1991;30(46):11164-72.
1991: Fujimori K; Fisher D R; Weinstein J N
Integrated microscopic-macroscopic pharmacology of monoclonal antibody radioconjugates: the radiation dose distribution.
Cancer research 1991;51(18):4821-7.
1991: van Osdol W; Fujimori K; Weinstein J N
An analysis of monoclonal antibody distribution in microscopic tumor nodules: consequences of a "binding site barrier".
Cancer research 1991;51(18):4776-84.
1991: Szebeni J; Weinstein J N
Dipyridamole binding to proteins in human plasma and tissue culture media.
The Journal of laboratory and clinical medicine 1991;117(6):485-92.
1991: Patel S S; Szebeni J; Wahl L M; Weinstein J N
Differential inhibition of 2'-deoxycytidine salvage as a possible mechanism for potentiation of the anti-human immunodeficiency virus activity of 2',3'-dideoxycytidine by dipyridamole.
Antimicrobial agents and chemotherapy 1991;35(6):1250-3.
1991: Szebeni J; Patel S S; Hung K; Wahl L M; Weinstein J N
Effects of thymidine and uridine on the phosphorylation of 3'-azido-3'-deoxythymidine (zidovudine) in human mononuclear cells.
Antimicrobial agents and chemotherapy 1991;35(1):198-200.
1991: Mulshine J L; Carrasquillo J A; Weinstein J N; Keenan A M; Reynolds J C; Herdt J; Bunn P A; Sausville E; Eddy J; Cotelingam J D
Direct intralymphatic injection of radiolabeled 111In-T101 in patients with cutaneous T-cell lymphoma.
Cancer research 1991;51(2):688-95.
1990: Ashorn P; Moss B; Weinstein J N; Chaudhary V K; FitzGerald D J; Pastan I; Berger E A
Elimination of infectious human immunodeficiency virus from human T-cell cultures by synergistic action of CD4-Pseudomonas exotoxin and reverse transcriptase inhibitors.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(22):8889-93.
1990: Betageri G V; Szebeni J; Hung K; Patel S S; Wahl L M; Corcoran M; Weinstein J N
Effect of dipyridamole on transport and phosphorylation of thymidine and 3'-azido-3'-deoxythymidine in human monocyte/macrophages.
Biochemical pharmacology 1990;40(4):867-70.
1990: Viswanadhan V N; Ghose A K; Weinstein J N
Mapping the binding site of the nucleoside transporter protein: a 3D-OSAR study.
Biochimica et biophysica acta 1990;1039(3):356-66.
1990: Fujimori K; Covell D G; Fletcher J E; Weinstein J N
A modeling analysis of monoclonal antibody percolation through tumors: a binding-site barrier.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1990;31(7):1191-8.
1990: Szebeni J; Wahl S M; Betageri G V; Wahl L M; Gartner S; Popovic M; Parker R J; Black C D; Weinstein J N
Inhibition of HIV-1 in monocyte/macrophage cultures by 2',3'-dideoxycytidine-5'-triphosphate, free and in liposomes.
AIDS research and human retroviruses 1990;6(5):691-702.
1990: Viswanadhan V N; Weinstein J N; Elwood P C
Secondary structure of the human membrane-associated folate binding protein using a joint prediction approach.
Journal of biomolecular structure & dynamics 1990;7(4):985-1001.
1990: Weinstein J N; Bunow B; Weislow O S; Schinazi R F; Wahl S M; Wahl L M; Szebeni J
Synergistic drug combinations in AIDS therapy. Dipyridamole/3'-azido-3'-deoxythymidine in particular and principles of analysis in general.
Annals of the New York Academy of Sciences 1990;616():367-84.
1989: Fujimori K; Covell D G; Fletcher J E; Weinstein J N
Modeling analysis of the global and microscopic distribution of immunoglobulin G, F(ab')2, and Fab in tumors.
Cancer research 1989;49(20):5656-63.
1989: Szebeni J; Wahl S M; Popovic M; Wahl L M; Gartner S; Fine R L; Skaleric U; Friedmann R M; Weinstein J N
Dipyridamole potentiates the inhibition by 3'-azido-3'-deoxythymidine and other dideoxynucleosides of human immunodeficiency virus replication in monocyte-macrophages.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(10):3842-6.
1988: Black C D; Kroczek R A; Barbet J; Weinstein J N; Shevach E M
Induction of IL-2 receptor expression in vivo: response to concanavalin A.
Cellular immunology 1988;111(2):420-32.
1987: Holton O D; Black C D; Parker R J; Covell D G; Barbet J; Sieber S M; Talley M J; Weinstein J N
Biodistribution of monoclonal IgG1, F(ab')2, and Fab' in mice after intravenous injection. Comparison between anti-B cell (anti-Lyb8.2) and irrelevant (MOPC-21) antibodies.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(9):3041-9.
1987: Keenan A M; Weinstein J N; Carrasquillo J A; Bunn P A; Reynolds J C; Foon K A; Smarte N C; Ghosh B; Fejka R M; Larson S M
Immunolymphoscintigraphy and the dose dependence of 111In-labeled T101 monoclonal antibody in patients with cutaneous T-cell lymphoma.
Cancer research 1987;47(22):6093-9.
1987: Mulshine J L; Keenan A M; Carrasquillo J A; Walsh T; Linnoila R I; Holton O D; Harwell J; Larson S M; Bunn P A; Weinstein J N
Immunolymphoscintigraphy of pulmonary and mediastinal lymph nodes in dogs: a new approach to lung cancer imaging.
Cancer research 1987;47(13):3572-6.
1987: Eger R R; Covell D G; Carrasquillo J A; Abrams P G; Foon K A; Reynolds J C; Schroff R W; Morgan A C; Larson S M; Weinstein J N
Kinetic model for the biodistribution of an 111In-labeled monoclonal antibody in humans.
Cancer research 1987;47(12):3328-36.
1987: Parker R J; Keenan A M; Dower S K; Steller M A; Holton O D; Sieber S M; Weinstein J N
Targeting of murine radiolabeled monoclonal antibodies in the lymphatics.
Cancer research 1987;47(8):2073-6.
1987: Weinstein J N; Eger R R; Covell D G; Black C D; Mulshine J; Carrasquillo J A; Larson S M; Keenan A M
The pharmacology of monoclonal antibodies.
Annals of the New York Academy of Sciences 1987;507():199-210.
1986: Lotze M T; Carrasquillo J A; Weinstein J N; Bryant G J; Perentesis P; Reynolds J C; Matis L A; Eger R R; Keenan A M; Hellström I
Monoclonal antibody imaging of human melanoma. Radioimmunodetection by subcutaneous or systemic injection.
Annals of surgery 1986;204(3):223-35.
1986: Covell D G; Barbet J; Holton O D; Black C D; Parker R J; Weinstein J N
Pharmacokinetics of monoclonal immunoglobulin G1, F(ab')2, and Fab' in mice.
Cancer research 1986;46(8):3969-78.
1986: Steller M A; Parker R J; Covell D G; Holton O D; Keenan A M; Sieber S M; Weinstein J N
Optimization of monoclonal antibody delivery via the lymphatics: the dose dependence.
Cancer research 1986;46(4 Pt 1):1830-4.
1986: Weinstein J N; Holton O D; Black C D; Keenan A M; Covell D G; Spaulding G F; Barbet J; Steller M A; Sieber S M; Talley M J
Regional delivery of monoclonal antitumor antibodies: detection and possible treatment of lymph node metastases.
Progress in clinical and biological research 1986;212():169-81.
1985: Weinstein J N; Parker R J; Holton O D; Keenan A M; Covell D G; Black C D; Sieber S M
Lymphatic delivery of monoclonal antibodies: potential for detection and treatment of lymph node metastases.
Cancer investigation 1985;3(1):85-95.
1984: Weinstein J N; Steller M A; Covell D G; Holton O D; Keenan A M; Sieber S M; Parker R J
Monoclonal antitumor antibodies in the lymphatics.
Cancer treatment reports 1984;68(1):257-64.
1983: Weinstein J N; Steller M A; Keenan A M; Covell D G; Key M E; Sieber S M; Oldham R K; Hwang K M; Parker R J
Monoclonal antibodies in the lymphatics: selective delivery to lymph node metastases of a solid tumor.
Science (New York, N.Y.) 1983;222(4622):423-6.
1982: Weinstein J N; Parker R J; Keenan A M; Dower S K; Morse H C; Sieber S M
Monoclonal anitbodies in the lymphatics: toward the diagnosis and therapy of tumor metastases.
Science (New York, N.Y.) 1982;218(4579):1334-7.
1981: Parker R J; Sieber S M; Weinstein J N
Effect of liposome encapsulation of a fluorescent dye on its uptake by the lymphatics of the rat.
Pharmacology 1981;23(3):128-36.

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