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Bruce Weintraub

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Julia Reinfelder; Mariusz W Szkudlinski; Bruce D Weintraub; Vladimir Wolf; Catherine A Foss; Valerie Fremont; Torsten Kuwert; Simone Maschauer; Sridhar Nimmagadda ; Martin G Pomper; Olaf Prante
Effects of recombinant human thyroid-stimulating hormone superagonists on thyroidal uptake of 18F-fluorodeoxyglucose and radioiodide.
PAMELA SCHROEDER; Bryan R Haugen; Furio Pacini; Christoph Reiners; Martin Schlumberger; Steven I Sherman; David S Cooper; Kathryn G Schuff; Lewis E Braverman; Monica C Skarulis; terry Davies; Ernest L Mazzaferri; Gilbert H Daniels; Douglas S Ross; Markus Luster; Mary H Samuels; Bruce D Weintraub; E Chester Ridgway; Paul W Ladenson
A comparison of short-term changes in health-related quality of life in thyroid carcinoma patients undergoing diagnostic evaluation with recombinant human thyrotropin compared with thyroid hormone withdrawal.
Mariusz Szkudlinski; Valerie Fremont; Catherine Ronin; Bruce D Weintraub
Thyroid-stimulating hormone and thyroid-stimulating hormone receptor structure-function relationships.

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2011: Julia Reinfelder; Mariusz W Szkudlinski; Bruce D Weintraub; Vladimir Wolf; Catherine A Foss; Valerie Fremont; Torsten Kuwert; Simone Maschauer; Sridhar Nimmagadda ; Martin G Pomper; Olaf Prante
Effects of recombinant human thyroid-stimulating hormone superagonists on thyroidal uptake of 18F-fluorodeoxyglucose and radioiodide.
Thyroid : official journal of the American Thyroid Association 2011;21(7):783-92.
2006: PAMELA SCHROEDER; Bryan R Haugen; Furio Pacini; Christoph Reiners; Martin Schlumberger; Steven I Sherman; David S Cooper; Kathryn G Schuff; Lewis E Braverman; Monica C Skarulis; terry Davies; Ernest L Mazzaferri; Gilbert H Daniels; Douglas S Ross; Markus Luster; Mary H Samuels; Bruce D Weintraub; E Chester Ridgway; Paul W Ladenson
A comparison of short-term changes in health-related quality of life in thyroid carcinoma patients undergoing diagnostic evaluation with recombinant human thyrotropin compared with thyroid hormone withdrawal.
The Journal of clinical endocrinology and metabolism 2006;91(3):878-84.
2002: Mariusz Szkudlinski; Valerie Fremont; Catherine Ronin; Bruce D Weintraub
Thyroid-stimulating hormone and thyroid-stimulating hormone receptor structure-function relationships.
Physiological reviews 2002;82(2):473-502.
2000: Masahiro Kaneshige; Kumiko Kaneshige; X Zhu; A Dace; L Garrett; Todd A Carter; Rasa Kazlauskaite; Daniel G Pankratz; Anthony Wynshaw-Boris; S Refetoff; Bruce D Weintraub; Mark C Willingham; Carrolee Barlow; S y Cheng
Mice with a targeted mutation in the thyroid hormone beta receptor gene exhibit impaired growth and resistance to thyroid hormone.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(24):13209-14.
2000: M Zhang; K P Tong; Valerie Fremont; J Chen; Prema Narayan; J David Puett; Bruce D Weintraub; Mariusz Szkudlinski
The extracellular domain suppresses constitutive activity of the transmembrane domain of the human TSH receptor: implications for hormone-receptor interaction and antagonist design.
Endocrinology 2000;141(9):3514-7.
2000: H Leitolf; K P Tong; M Grossmann; Bruce D Weintraub; Mariusz Szkudlinski
Bioengineering of human thyrotropin superactive analogs by site-directed "lysine-scanning" mutagenesis. Cooperative effects between peripheral loops.
The Journal of biological chemistry 2000;275(35):27457-65.
2000: Mariusz Szkudlinski; M Grossmann; H Leitolf; Bruce D Weintraub
Human thyroid-stimulating hormone: structure-function analysis.
Methods (San Diego, Calif.) 2000;21(1):67-81.
1999: Bryan R Haugen; Furio Pacini; Christoph Reiners; Martin Schlumberger; Paul W Ladenson; Steven I Sherman; David S Cooper; KE Graham; Lewis E Braverman; Monica C Skarulis; terry Davies; L J DeGroot; Ernest L Mazzaferri; Gilbert H Daniels; Douglas S Ross; Markus Luster; Mary H Samuels; D V Becker; Harry R Maxon; R R Cavalieri; CA Spencer; K McEllin; Bruce D Weintraub; E Chester Ridgway
A comparison of recombinant human thyrotropin and thyroid hormone withdrawal for the detection of thyroid remnant or cancer.
The Journal of clinical endocrinology and metabolism 1999;84(11):3877-85.
1999: S Sasaki; L A Lesoon-Wood; A Dey; T Kuwata; Bruce D Weintraub; Glen Humphrey; Wen-Ming Yang; E Seto; Paul M Yen; Bruce H Howard; Keiko Ozato
Ligand-induced recruitment of a histone deacetylase in the negative-feedback regulation of the thyrotropin beta gene.
The EMBO journal 1999;18(19):5389-98.
1999: Bruce D Weintraub; Mariusz Szkudlinski
Development and in vitro characterization of human recombinant thyrotropin.
Thyroid : official journal of the American Thyroid Association 1999;9(5):447-50.
1999: Françoise Brucker-Davis; Edward H Oldfield; Monica C Skarulis; John L Doppman; Bruce D Weintraub
Thyrotropin-secreting pituitary tumors: diagnostic criteria, thyroid hormone sensitivity, and treatment outcome in 25 patients followed at the National Institutes of Health.
The Journal of clinical endocrinology and metabolism 1999;84(2):476-86.
1998: MP McDonald; R Wong; G Goldstein; Bruce D Weintraub; Sheue-Yann Cheng; Jacqueline N Crawley
Hyperactivity and learning deficits in transgenic mice bearing a human mutant thyroid hormone beta1 receptor gene.
Learning & memory (Cold Spring Harbor, N.Y.) 1998;5(4-5):289-301.
1998: M Grossmann; H Leitolf; Bruce D Weintraub; Mariusz Szkudlinski
A rational design strategy for protein hormone superagonists.
Nature biotechnology 1998;16(9):871-5.
1998: Da-Wei Gong; Sheng Bi; Bruce D Weintraub; Marc L Reitman
Rat mitochondrial glycerol-3-phosphate dehydrogenase gene: multiple promoters, high levels in brown adipose tissue, and tissue-specific regulation by thyroid hormone.
DNA and cell biology 1998;17(3):301-9.
1997: Q L Li; Pei Feng; T Satoh; Z X Shi; R Wang; Bruce D Weintraub; JF Wilber
Regulation of the human TRH (hTRH) gene by human thyroid hormone receptor beta 1 (hTR beta 1) mutants.
Endocrine research 1997;23(4):297-309.
1997: Paul W Ladenson; Lewis E Braverman; Ernest L Mazzaferri; Françoise Brucker-Davis; David S Cooper; J R Garber; Fredric E Wondisford; terry Davies; L J DeGroot; Gilbert H Daniels; Douglas S Ross; Bruce D Weintraub
Comparison of administration of recombinant human thyrotropin with withdrawal of thyroid hormone for radioactive iodine scanning in patients with thyroid carcinoma.
The New England journal of medicine 1997;337(13):888-96.
1997: M Grossmann; R Wong; Mariusz Szkudlinski; Bruce D Weintraub
Human thyroid-stimulating hormone (hTSH) subunit gene fusion produces hTSH with increased stability and serum half-life and compensates for mutagenesis-induced defects in subunit association.
The Journal of biological chemistry 1997;272(34):21312-6.
1997: M Grossmann; Bruce D Weintraub; Mariusz Szkudlinski
Novel insights into the molecular mechanisms of human thyrotropin action: structural, physiological, and therapeutic implications for the glycoprotein hormone family.
Endocrine reviews 1997;18(4):476-501.
1997: M Grossmann; Mariusz Szkudlinski; R Wong; J A Dias; Tae H Ji; Bruce D Weintraub
Substitution of the seat-belt region of the thyroid-stimulating hormone (TSH) beta-subunit with the corresponding regions of choriogonadotropin or follitropin confers luteotropic but not follitropic activity to chimeric TSH.
The Journal of biological chemistry 1997;272(24):15532-40.
1997: R Wong; V V Vasilyev; Y T Ting; D I Kutler; M C Willingham; Bruce D Weintraub; S Cheng
Transgenic mice bearing a human mutant thyroid hormone beta 1 receptor manifest thyroid function anomalies, weight reduction, and hyperactivity.
Molecular medicine (Cambridge, Mass.) 1997;3(5):303-14.
1997: Peter Hauser; R Soler; Françoise Brucker-Davis; Bruce D Weintraub
Thyroid hormones correlate with symptoms of hyperactivity but not inattention in attention deficit hyperactivity disorder.
Psychoneuroendocrinology 1997;22(2):107-14.
1997: M Grossmann; R Wong; N G Teh; J E Tropea; J East-Palmer; Bruce D Weintraub; Mariusz Szkudlinski
Expression of biologically active human thyrotropin (hTSH) in a baculovirus system: effect of insect cell glycosylation on hTSH activity in vitro and in vivo.
Endocrinology 1997;138(1):92-100.
1996: Paolo Beck-Peccoz; Françoise Brucker-Davis; Luca Persani; R C Smallridge; Bruce D Weintraub
Thyrotropin-secreting pituitary tumors.
Endocrine reviews 1996;17(6):610-38.
1996: Mariusz Szkudlinski; M Grossmann; Bruce D Weintraub
Structure-function studies of human TSH: new advances in design of glycoprotein hormone analogs.
Trends in endocrinology and metabolism: TEM 1996;7(8):277-86.
1996: Mariusz Szkudlinski; N G Teh; M Grossmann; J E Tropea; Bruce D Weintraub
Engineering human glycoprotein hormone superactive analogues.
Nature biotechnology 1996;14(10):1257-63.
1996: Françoise Brucker-Davis; James C Reynolds; Monica C Skarulis; Douglas L Fraker; H Richard Alexander; Bruce D Weintraub; Jacob Robbins
False-positive iodine-131 whole-body scans due to cholecystitis and sebaceous cyst.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996;37(10):1690-3.
1996: Françoise Brucker-Davis; Monica C Skarulis; A Pikus; D Ishizawar; M A Mastroianni; M Koby; Bruce D Weintraub
Prevalence and mechanisms of hearing loss in patients with resistance to thyroid hormone.
The Journal of clinical endocrinology and metabolism 1996;81(8):2768-72.
1996: M K Kim; L A Lesoon-Wood; Bruce D Weintraub; J H Chung
A soluble transcription factor, Oct-1, is also found in the insoluble nuclear matrix and possesses silencing activity in its alanine-rich domain.
Molecular and cellular biology 1996;16(8):4366-77.
1996: John A Matochik; Alan J Zametkin; Robert M Cohen; Peter Hauser; Bruce D Weintraub
Abnormalities in sustained attention and anterior cingulate metabolism in subjects with resistance to thyroid hormone.
Brain research 1996;723(1-2):23-8.
1996: M Grossmann; Mariusz Szkudlinski; J A Dias; H Xia; R Wong; J David Puett; Bruce D Weintraub
Site-directed mutagenesis of amino acids 33-44 of the common alpha-subunit reveals different structural requirements for heterodimer expression among the glycoprotein hormones and suggests that cyclic adenosine 3',5'-monophosphate production and growth promotion are potentially dissociable functions of human thyrotropin.
Molecular endocrinology (Baltimore, Md.) 1996;10(6):769-79.
1996: Qiong Dong; Françoise Brucker-Davis; Bruce D Weintraub; R C Smallridge; F E Carr; J Battey; Allen Spiegel; A Shenker
Screening of candidate oncogenes in human thyrotroph tumors: absence of activating mutations of the G alpha q, G alpha 11, G alpha s, or thyrotropin-releasing hormone receptor genes.
The Journal of clinical endocrinology and metabolism 1996;81(3):1134-40.
1996: Da-Wei Gong; Sheng Bi; Richard E Pratley; Bruce D Weintraub
Genomic structure and promoter analysis of the human obese gene.
The Journal of biological chemistry 1996;271(8):3971-4.
1996: D Seto; Bruce D Weintraub
Rapid molecular diagnosis of mutations associated with generalized thyroid hormone resistance by PCR-coupled automated direct sequencing of genomic DNA: detection of two novel mutations.
Human mutation 1996;8(3):247-57.
1995: M Grossmann; Mariusz Szkudlinski; J E Tropea; L A Bishop; N R Thotakura; P R Schofield; Bruce D Weintraub
Expression of human thyrotropin in cell lines with different glycosylation patterns combined with mutagenesis of specific glycosylation sites. Characterization of a novel role for the oligosaccharides in the in vitro and in vivo bioactivity.
The Journal of biological chemistry 1995;270(49):29378-85.
1995: R S Krouse; Richard E Royal; G Heywood; Bruce D Weintraub; Donald E White; Seth M Steinberg; STEVEN ROSENBERG; Douglas J Schwartzentruber
Thyroid dysfunction in 281 patients with metastatic melanoma or renal carcinoma treated with interleukin-2 alone.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1995;18(4):272-8.
1995: M B Grace; G S Bambeck; G S Buzard; Bruce D Weintraub
Transverse temperature-gradient single-strand conformation polymorphism analysis for temperature optimization of 'Cold'-SSCP mutation detection.
Nucleic acids research 1995;23(20):4224-6.
1995: Françoise Brucker-Davis; Monica C Skarulis; M B Grace; J Benichou; Peter Hauser; E Wiggs; Bruce D Weintraub
Genetic and clinical features of 42 kindreds with resistance to thyroid hormone. The National Institutes of Health Prospective Study.
Annals of internal medicine 1995;123(8):572-83.
1995: Mariusz Szkudlinski; N R Thotakura; Bruce D Weintraub
Subunit-specific functions of N-linked oligosaccharides in human thyrotropin: role of terminal residues of alpha- and beta-subunit oligosaccharides in metabolic clearance and bioactivity.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(20):9062-6.
1995: L Joshi; Y Murata; Fredric E Wondisford; Mariusz Szkudlinski; R Desai; Bruce D Weintraub
Recombinant thyrotropin containing a beta-subunit chimera with the human chorionic gonadotropin-beta carboxy-terminus is biologically active, with a prolonged plasma half-life: role of carbohydrate in bioactivity and metabolic clearance.
Endocrinology 1995;136(9):3839-48.
1995: Mariusz Szkudlinski; N R Thotakura; J E Tropea; M Grossmann; Bruce D Weintraub
Asparagine-linked oligosaccharide structures determine clearance and organ distribution of pituitary and recombinant thyrotropin.
Endocrinology 1995;136(8):3325-30.
1995: M Grossmann; Mariusz Szkudlinski; H Zeng; Z Kraiem; Inhae Ji; J E Tropea; Tae H Ji; Bruce D Weintraub
Role of the carboxy-terminal residues of the alpha-subunit in the expression and bioactivity of human thyroid-stimulating hormone.
Molecular endocrinology (Baltimore, Md.) 1995;9(8):948-58.
1995: Christiana M Leonard; P Martinez; Bruce D Weintraub; Peter Hauser
Magnetic resonance imaging of cerebral anomalies in subjects with resistance to thyroid hormone.
American journal of medical genetics 1995;60(3):238-43.
1995: H Leitolf; Mariusz Szkudlinski; Cuong Hoang-Vu; N R Thotakura; A von zur Mühlen; G Brabant; Bruce D Weintraub
Effects of continuous and pulsatile administration of pituitary rat thyrotropin and recombinant human thyrotropin in a chronically cannulated rat.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1995;27(4):173-8.
1995: L A Lesoon-Wood; W H Kim; H K Kleinman; Bruce D Weintraub; A James Mixson
Systemic gene therapy with p53 reduces growth and metastases of a malignant human breast cancer in nude mice.
Human gene therapy 1995;6(4):395-405.
1995: R Wong; X G Zhu; M A Pineda; Sheue-Yann Cheng; Bruce D Weintraub
Cell type-dependent modulation of the dominant negative action of human mutant thyroid hormone beta 1 receptors.
Molecular medicine (Cambridge, Mass.) 1995;1(3):306-19.
1995: Laurie E Cohen; Fredric E Wondisford; A Salvatoni; M Maghnie; F Brucker-Davis; Bruce D Weintraub; Sally Radovick
A "hot spot" in the Pit-1 gene responsible for combined pituitary hormone deficiency: clinical and molecular correlates.
The Journal of clinical endocrinology and metabolism 1995;80(2):679-84.
1995: J East-Palmer; Mariusz Szkudlinski; J Lee; N R Thotakura; Bruce D Weintraub
A novel, nonradioactive in vivo bioassay of thyrotropin (TSH).
Thyroid : official journal of the American Thyroid Association 1995;5(1):55-9.
1995: M B Grace; G S Buzard; Bruce D Weintraub
Allele-specific associated polymorphism analysis: novel modification of SSCP for mutation detection in heterozygous alleles using the paradigm of resistance to thyroid hormone.
Human mutation 1995;6(3):232-42.
1994: N R Thotakura; Mariusz Szkudlinski; Bruce D Weintraub
Structure-function studies of oligosaccharides of recombinant human thyrotrophin by sequential deglycosylation and resialylation.
Glycobiology 1994;4(4):525-33.
1994: Peter Hauser; Alan J Zametkin; P Martinez; Benedetto Vitiello; John A Matochik; A James Mixson; Bruce D Weintraub
ADHD and the thyroid controversy.
Journal of the American Academy of Child and Adolescent Psychiatry 1994;33(5):756-8.
1994: Paolo Beck-Peccoz; V Krishna K Chatterjee; W W Chin; L J DeGroot; J Larry Jameson; H Nakamura; S Refetoff; S J Usala; Bruce D Weintraub
Nomenclature of thyroid hormone receptor beta gene mutations in resistance to thyroid hormone: consensus statement from the First Workshop on Thyroid Hormone Resistance, 10-11 July 1993, Cambridge, UK.
Clinical endocrinology 1994;40(5):697-700.
1994: Paolo Beck-Peccoz; V Krishna K Chatterjee; W W Chin; L J DeGroot; J Larry Jameson; H Nakamura; S Refetoff; S J Usala; Bruce D Weintraub
Nomenclature of thyroid hormone receptor-beta gene mutations in resistance to thyroid hormone: consensus statement from the First Workshop on Thyroid Hormone Resistance, 10-11th July 1993, Cambridge, UK.
European journal of endocrinology / European Federation of Endocrine Societies 1994;130(4):426-8.
1994: Paolo Beck-Peccoz; V Krishna K Chatterjee; W W Chin; L J DeGroot; J Larry Jameson; H Nakamura; S Refetoff; S J Usala; Bruce D Weintraub
Nomenclature of thyroid hormone receptor beta-gene mutations in resistance to thyroid hormone: consensus statement from the first workshop on thyroid hormone resistance, July 10-11, 1993, Cambridge, United Kingdom.
The Journal of clinical endocrinology and metabolism 1994;78(4):990-3.
1994: Paolo Beck-Peccoz; V Krishna K Chatterjee; W W Chin; L J DeGroot; J Larry Jameson; H Nakamura; S Refetoff; S J Usala; Bruce D Weintraub
Nomenclature of thyroid hormone receptor beta gene mutations in resistance to thyroid hormone. First workshop on thyroid hormone resistance, July 10-11, 1993, Cambridge, U.K.
Journal of endocrinological investigation 1994;17(4):283-7.
1994: Paolo Beck-Peccoz; V Krishna K Chatterjee; W W Chin; L J DeGroot; J Larry Jameson; H Nakamura; S Refetoff; S J Usala; Bruce D Weintraub
Nomenclature of thyroid hormone receptor beta gene mutations in resistance to thyroid hormone: consensus statement from the first workshop on thyroid hormone resistance, July 10-11th 1993, Cambridge, U.K.
Thyroid : official journal of the American Thyroid Association 1994;4(1):135-7.
1993: M K Kim; J H McClaskey; D L Bodenner; Bruce D Weintraub
An AP-1-like factor and the pituitary-specific factor Pit-1 are both necessary to mediate hormonal induction of human thyrotropin beta gene expression.
The Journal of biological chemistry 1993;268(31):23366-75.
1993: Christoph A Meier; C Parkison; A Chen; K Ashizawa; S C Meier-Heusler; P Muchmore; Sheue-Yann Cheng; Bruce D Weintraub
Interaction of human beta 1 thyroid hormone receptor and its mutants with DNA and retinoid X receptor beta. T3 response element-dependent dominant negative potency.
The Journal of clinical investigation 1993;92(4):1986-93.
1993: Mariusz Szkudlinski; N R Thotakura; I Bucci; L R Joshi; A Tsai; J East-Palmer; J Shiloach; Bruce D Weintraub
Purification and characterization of recombinant human thyrotropin (TSH) isoforms produced by Chinese hamster ovary cells: the role of sialylation and sulfation in TSH bioactivity.
Endocrinology 1993;133(4):1490-503.
1993: E S Cole; K Lee; K Lauziere; C Kelton; S Chappel; Bruce D Weintraub; D Ferrara; P Peterson; R Bernasconi; Tim Edmunds
Recombinant human thyroid stimulating hormone: development of a biotechnology product for detection of metastatic lesions of thyroid carcinoma.
Bio/technology (Nature Publishing Company) 1993;11(9):1014-24.
1993: P Chanson; Bruce D Weintraub; A G Harris
Octreotide therapy for thyroid-stimulating hormone-secreting pituitary adenomas. A follow-up of 52 patients.
Annals of internal medicine 1993;119(3):236-40.
1993: A James Mixson; Peter Hauser; G Tennyson; J C Renault; D L Bodenner; Bruce D Weintraub
Differential expression of mutant and normal beta T3 receptor alleles in kindreds with generalized resistance to thyroid hormone.
The Journal of clinical investigation 1993;91(5):2296-300.
1993: Peter Hauser; Alan J Zametkin; P Martinez; Benedetto Vitiello; John A Matochik; A James Mixson; Bruce D Weintraub
Attention deficit-hyperactivity disorder in people with generalized resistance to thyroid hormone.
The New England journal of medicine 1993;328(14):997-1001.
1993: A James Mixson; J C Renault; S Ransom; D L Bodenner; Bruce D Weintraub
Identification of a novel mutation in the gene encoding the beta-triiodothyronine receptor in a patient with apparent selective pituitary resistance to thyroid hormone.
Clinical endocrinology 1993;38(3):227-34.
1993: A James Mixson; T C Friedman; D A Katz; I M Feuerstein; Jeffery Taubenberger; J M Colandrea; John L Doppman; E H Oldfield; Bruce D Weintraub
Thyrotropin-secreting pituitary carcinoma.
The Journal of clinical endocrinology and metabolism 1993;76(2):529-33.
1993: M K Kim; J H McClaskey; D L Bodenner; Bruce D Weintraub
A c-fos/c-jun-like factor and the pituitary-specific factor Pit-1 are both necessary to mediate induction of the human thyrotropin beta promoter.
Transactions of the Association of American Physicians 1993;106():62-8.
1992: D L Bodenner; J H McClaskey; M K Kim; A James Mixson; Bruce D Weintraub
The proto-oncogenes c-fos and c-jun modulate thyroid hormone inhibition of human thyrotropin beta subunit gene expression in opposite directions.
Biochemical and biophysical research communications 1992;189(2):1050-6.
1992: A James Mixson; R Parrilla; S C Ransom; E A Wiggs; J H McClaskey; Peter Hauser; Bruce D Weintraub
Correlations of language abnormalities with localization of mutations in the beta-thyroid hormone receptor in 13 kindreds with generalized resistance to thyroid hormone: identification of four new mutations.
The Journal of clinical endocrinology and metabolism 1992;75(4):1039-45.
1992: Sally Radovick; M Nations; Y Du; L A Berg; Bruce D Weintraub; Fredric E Wondisford
A mutation in the POU-homeodomain of Pit-1 responsible for combined pituitary hormone deficiency.
Science (New York, N.Y.) 1992;257(5073):1115-8.
1992: N R Thotakura; R K Desai; Mariusz Szkudlinski; Bruce D Weintraub
The role of the oligosaccharide chains of thyrotropin alpha- and beta-subunits in hormone action.
Endocrinology 1992;131(1):82-8.
1992: Jean-Jacques Staub; B U Althaus; H Engler; A S Ryff; P Trabucco; K Marquardt; D Burckhardt; J Girard; Bruce D Weintraub
Spectrum of subclinical and overt hypothyroidism: effect on thyrotropin, prolactin, and thyroid reserve, and metabolic impact on peripheral target tissues.
The American journal of medicine 1992;92(6):631-42.
1992: M Lisker-Melman; A M Di Bisceglie; stephen usala; Bruce D Weintraub; L M Murray; Jay H Hoofnagle
Development of thyroid disease during therapy of chronic viral hepatitis with interferon alfa.
Gastroenterology 1992;102(6):2155-60.
1992: Robert W Lash; R K Desai; C A Zimmerman; M R Flack; T Yoshida; Fredric E Wondisford; Bruce D Weintraub
Mutations of the human thyrotropin-beta subunit glycosylation site reduce thyrotropin synthesis independent of changes in glycosylation status.
Journal of endocrinological investigation 1992;15(4):255-63.
1992: Hans Jürgen Steinfelder; Sally Radovick; M A Mroczynski; Peter Hauser; J H McClaskey; Bruce D Weintraub; Fredric E Wondisford
Role of a pituitary-specific transcription factor (pit-1/GHF-1) or a closely related protein in cAMP regulation of human thyrotropin-beta subunit gene expression.
The Journal of clinical investigation 1992;89(2):409-19.
1991: Douglas J Schwartzentruber; Donald E White; M H Zweig; Bruce D Weintraub; STEVEN ROSENBERG
Thyroid dysfunction associated with immunotherapy for patients with cancer.
Cancer 1991;68(11):2384-90.
1991: R Parrilla; A James Mixson; J A McPherson; J H McClaskey; Bruce D Weintraub
Characterization of seven novel mutations of the c-erbA beta gene in unrelated kindreds with generalized thyroid hormone resistance. Evidence for two "hot spot" regions of the ligand binding domain.
The Journal of clinical investigation 1991;88(6):2123-30.
1991: D L Bodenner; M A Mroczynski; Bruce D Weintraub; Sally Radovick; Fredric E Wondisford
A detailed functional and structural analysis of a major thyroid hormone inhibitory element in the human thyrotropin beta-subunit gene.
The Journal of biological chemistry 1991;266(32):21666-73.
1991: Sally Radovick; C M Ticknor; Y Nakayama; A C Notides; A Rahman; Bruce D Weintraub; G B Cutler; Fredric E Wondisford
Evidence for direct estrogen regulation of the human gonadotropin-releasing hormone gene.
The Journal of clinical investigation 1991;88(5):1649-55.
1991: K B Ain; S Refetoff; HENRY FEIN; Bruce D Weintraub
Pseudomalabsorption of levothyroxine.
JAMA : the journal of the American Medical Association 1991;266(15):2118-20.
1991: F W Holland; P S Brown; Bruce D Weintraub; R E Clark
Cardiopulmonary bypass and thyroid function: a "euthyroid sick syndrome".
The Annals of thoracic surgery 1991;52(1):46-50.
1991: T L Francavilla; R S Miletich; D DeMichele; Nicholas Patronas; Edward H Oldfield; Bruce D Weintraub; G Di Chiro
Positron emission tomography of pituitary macroadenomas: hormone production and effects of therapies.
Neurosurgery 1991;28(6):826-33.
1991: Sally Radovick; S Wray; E Lee; D K Nicols; Y Nakayama; Bruce D Weintraub; H Westphal; G B Cutler; Fredric E Wondisford
Migratory arrest of gonadotropin-releasing hormone neurons in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(8):3402-6.
1991: Hans Jürgen Steinfelder; Peter Hauser; Y Nakayama; Sally Radovick; J H McClaskey; T Taylor; Bruce D Weintraub; Fredric E Wondisford
Thyrotropin-releasing hormone regulation of human TSHB expression: role of a pituitary-specific transcription factor (Pit-1/GHF-1) and potential interaction with a thyroid hormone-inhibitory element.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(8):3130-4.
1991: HENRY FEIN; Kenneth D Burman; Y Y Djuh; stephen usala; Allen E Bale; Bruce D Weintraub; Robert C Smallridge
Tight linkage of the human c-erbA beta gene with the syndrome of generalized thyroid hormone resistance is present in multiple kindreds.
Journal of endocrinological investigation 1991;14(3):219-23.
1991: stephen usala; J B Menke; T L Watson; Fredric E Wondisford; Bruce D Weintraub; J Bérard; W E Bradley; S Ono; O T Mueller; Barry B Bercu
A homozygous deletion in the c-erbA beta thyroid hormone receptor gene in a patient with generalized thyroid hormone resistance: isolation and characterization of the mutant receptor.
Molecular endocrinology (Baltimore, Md.) 1991;5(3):327-35.
1991: M Yamada; Fredric E Wondisford; Sally Radovick; Y Nakayama; Bruce D Weintraub; JF Wilber
Assignment of human preprothyrotropin-releasing hormone (TRH) gene to chromosome 3.
Somatic cell and molecular genetics 1991;17(1):97-100.
1991: N R Thotakura; R K Desai; L G Bates; E S Cole; B M Pratt; Bruce D Weintraub
Biological activity and metabolic clearance of a recombinant human thyrotropin produced in Chinese hamster ovary cells.
Endocrinology 1991;128(1):341-8.
1991: stephen usala; J B Menke; T L Watson; W E Bérard; C Bradley; Allen E Bale; Robert W Lash; Bruce D Weintraub
A new point mutation in the 3,5,3'-triiodothyronine-binding domain of the c-erbA beta thyroid hormone receptor is tightly linked to generalized thyroid hormone resistance.
The Journal of clinical endocrinology and metabolism 1991;72(1):32-8.
1990: I E McCutcheon; Bruce D Weintraub; Edward H Oldfield
Surgical treatment of thyrotropin-secreting pituitary adenomas.
Journal of neurosurgery 1990;73(5):674-83.
1990: stephen usala; Fredric E Wondisford; T L Watson; J B Menke; Bruce D Weintraub
Thyroid hormone and DNA binding properties of a mutant c-erbA beta receptor associated with generalized thyroid hormone resistance.
Biochemical and biophysical research communications 1990;171(2):575-80.
1990: N R Thotakura; L LiCalzi; Bruce D Weintraub
The role of carbohydrate in thyrotropin action assessed by a novel approach using enzymatic deglycosylation.
The Journal of biological chemistry 1990;265(20):11527-34.
1990: N R Thotakura; Bruce D Weintraub; O P Bahl
The role of carbohydrate in human choriogonadotropin (hCG) action. Effects of N-linked carbohydrate chains from hCG and other glycoproteins on hormonal activity.
Molecular and cellular endocrinology 1990;70(3):263-72.
1990: Y Nakayama; Fredric E Wondisford; Robert W Lash; Allen E Bale; Bruce D Weintraub; G B Cutler; Sally Radovick
Analysis of gonadotropin-releasing hormone gene structure in families with familial central precocious puberty and idiopathic hypogonadotropic hypogonadism.
The Journal of clinical endocrinology and metabolism 1990;70(5):1233-8.
1990: John L Doppman; D L Miller; N J Patronas; E H Oldfield; G R Merriam; Stuart J Frank; M R Flack; Bruce D Weintraub; P Gorden
The diagnosis of acromegaly: value of inferior petrosal sinus sampling.
AJR. American journal of roentgenology 1990;154(5):1075-7.
1990: P W Gyves; N Gesundheit; N R Thotakura; Bethel Stannard; George Decherney; Bruce D Weintraub
Changes in the sialylation and sulfation of secreted thyrotropin in congenital hypothyroidism.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(10):3792-6.
1990: M Yamada; Sally Radovick; Fredric E Wondisford; Y Nakayama; Bruce D Weintraub; JF Wilber
Cloning and structure of human genomic DNA and hypothalamic cDNA encoding human prepro thyrotropin-releasing hormone.
Molecular endocrinology (Baltimore, Md.) 1990;4(4):551-6.
1990: Sally Radovick; Fredric E Wondisford; Y Nakayama; M Yamada; G B Cutler; Bruce D Weintraub
Isolation and characterization of the human gonadotropin-releasing hormone gene in the hypothalamus and placenta.
Molecular endocrinology (Baltimore, Md.) 1990;4(3):476-80.
1990: Bruce D Weintraub
TSH immunoassay: relationship between glycosylation & bioactivity.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1990;17(7):657-60.
1990: stephen usala; G E Tennyson; Allen E Bale; Robert W Lash; N Gesundheit; Fredric E Wondisford; D Accili; Peter Hauser; Bruce D Weintraub
A base mutation of the C-erbA beta thyroid hormone receptor in a kindred with generalized thyroid hormone resistance. Molecular heterogeneity in two other kindreds.
The Journal of clinical investigation 1990;85(1):93-100.
1990: Bruce D Weintraub; Fredric E Wondisford; E A Farr; Hans Jürgen Steinfelder; Sally Radovick; N Gesundheit; P W Gyves; T Taylor; George Decherney
Pre-translational and post-translational regulation of TSH: relationship to bioactivity.
Hormone and metabolic research. Supplement series 1990;23():9-11.
1990: T Taylor; Fredric E Wondisford; T Blaine; Bruce D Weintraub
The paraventricular nucleus of the hypothalamus has a major role in thyroid hormone feedback regulation of thyrotropin synthesis and secretion.
Endocrinology 1990;126(1):317-24.
1989: Bethel Stannard; N Gesundheit; N R Thotakura; P W Gyves; C Ronin; Bruce D Weintraub
Differential effect of inhibitors of oligosaccharide processing on the secretion of thyrotropin from dispersed rodent pituitary cells.
Biochemical and biophysical research communications 1989;165(2):788-94.
1989: Stuart J Frank; N Gesundheit; John L Doppman; D L Miller; G R Merriam; E H Oldfield; Bruce D Weintraub
Preoperative lateralization of pituitary microadenomas by petrosal sinus sampling: utility in two patients with non-ACTH-secreting tumors.
The American journal of medicine 1989;87(6):679-82.
1989: N Gesundheit; P A Petrick; M Nissim; P A Dahlberg; John L Doppman; C H Emerson; L E Braverman; E H Oldfield; Bruce D Weintraub
Thyrotropin-secreting pituitary adenomas: clinical and biochemical heterogeneity. Case reports and follow-up of nine patients.
Annals of internal medicine 1989;111(10):827-35.
1989: T Taylor; Bruce D Weintraub
Altered thyrotropin (TSH) carbohydrate structures in hypothalamic hypothyroidism created by paraventricular nuclear lesions are corrected by in vivo TSH-releasing hormone administration.
Endocrinology 1989;125(4):2198-203.
1989: Fredric E Wondisford; E A Farr; Sally Radovick; Hans Jürgen Steinfelder; J M Moates; J H McClaskey; Bruce D Weintraub
Thyroid hormone inhibition of human thyrotropin beta-subunit gene expression is mediated by a cis-acting element located in the first exon.
The Journal of biological chemistry 1989;264(25):14601-4.
1989: N Gesundheit; P W Gyves; George Decherney; Bethel Stannard; R L Winston; Bruce D Weintraub
Characterization and charge distribution of the asparagine-linked oligosaccharides on secreted mouse thyrotropin and free alpha-subunits.
Endocrinology 1989;124(6):2967-77.
1989: P W Gyves; N Gesundheit; Bethel Stannard; George Decherney; Bruce D Weintraub
Alterations in the glycosylation of secreted thyrotropin during ontogenesis. Analysis of sialylated and sulfated oligosaccharides.
The Journal of biological chemistry 1989;264(11):6104-10.
1989: George Decherney; N Gesundheit; P W Gyves; C R Showalter; Bruce D Weintraub
Alterations in the sialylation and sulfation of secreted mouse thyrotropin in primary hypothyroidism.
Biochemical and biophysical research communications 1989;159(2):755-62.
1989: Bruce D Weintraub; M M Menezes-Ferreira; P A Petrick
Inappropriate secretion of TSH.
Endocrine research 1989;15(4):601-17.
1989: Bruce D Weintraub; Fredric E Wondisford; E A Farr; Hans Jürgen Steinfelder; Sally Radovick; N Gesundheit; P W Gyves; T Taylor; George Decherney
Pre-translational and post-translational regulation of TSH synthesis in normal and neoplastic thyrotrophs.
Hormone research 1989;32(1-3):22-4.
1989: Bruce D Weintraub; N Gesundheit; T Taylor; P W Gyves
Effect of TRH on TSH glycosylation and biological action.
Annals of the New York Academy of Sciences 1989;553():205-13.
1988: stephen usala; Allen E Bale; N Gesundheit; C Weinberger; Robert W Lash; Fredric E Wondisford; O W McBride; Bruce D Weintraub
Tight linkage between the syndrome of generalized thyroid hormone resistance and the human c-erbA beta gene.
Molecular endocrinology (Baltimore, Md.) 1988;2(12):1217-20.
1988: G Karsenty; C Alquier; C Jelsema; Bruce D Weintraub
Thyrotropin induces growth and iodothyronine production in a human thyroid cell line without affecting adenosine 3',5'-monophosphate production.
Endocrinology 1988;123(4):1977-83.
1988: Fredric E Wondisford; Sally Radovick; J M Moates; stephen usala; Bruce D Weintraub
Isolation and characterization of the human thyrotropin beta-subunit gene. Differences in gene structure and promoter function from murine species.
The Journal of biological chemistry 1988;263(25):12538-42.
1988: Allen E Bale; S Usala; C Weinberger; Bruce D Weintraub; O W McBride
A cDNA probe (PheA12) from the hc-(ERBA) gene on chromosome 3 detects a high frequency RFLP.
Nucleic acids research 1988;16(15):7756.
1988: Gyorgy Csako; Bruce D Weintraub; M H Zweig
The potency of immunoglobulin G fragments for inhibition of interference caused by anti-immunoglobulin antibodies in a monoclonal immunoradiometric assay for thyrotropin.
Clinical chemistry 1988;34(7):1481-3.
1988: Bethel Stannard; N Gesundheit; C Ronin; J Burnside; Bruce D Weintraub
Differential carbohydrate processing and secretion of thyrotropin and free alpha subunit. Effects of 1-deoxynojirimycin.
The Journal of biological chemistry 1988;263(17):8309-17.
1988: B B Kahn; Bruce D Weintraub; Gyorgy Csako; M H Zweig
Factitious elevation of thyrotropin in a new ultrasensitive assay: implications for the use of monoclonal antibodies in "sandwich" immunoassay.
The Journal of clinical endocrinology and metabolism 1988;66(3):526-33.
1988: T Taylor; N Gesundheit; P W Gyves; D M Jacobowitz; Bruce D Weintraub
Hypothalamic hypothyroidism caused by lesions in rat paraventricular nuclei alters the carbohydrate structure of secreted thyrotropin.
Endocrinology 1988;122(1):283-90.
1988: Marc R Blackman; Bruce D Weintraub; S W Rosen; S Mitchell Harman
Comparison of the effects of lung cancer, benign lung disease, and normal aging on pituitary-gonadal function in men.
The Journal of clinical endocrinology and metabolism 1988;66(1):88-95.
1987: Frederick W Miller; G F Moore; Bruce D Weintraub; A D Steinberg
Prevalence of thyroid disease and abnormal thyroid function test results in patients with systemic lupus erythematosus.
Arthritis and rheumatism 1987;30(10):1124-31.
1987: M Nissim; K O Lee; P A Petrick; P A Dahlberg; Bruce D Weintraub
A sensitive thyrotropin (TSH) bioassay based on iodide uptake in rat FRTL-5 thyroid cells: comparison with the adenosine 3',5'-monophosphate response to human serum TSH and enzymatically deglycosylated bovine and human TSH.
Endocrinology 1987;121(4):1278-87.
1987: C Ronin; M J Papandreou; C Canonne; Bruce D Weintraub
Carbohydrate chains of human thyrotropin are differentially susceptible to endoglycosidase removal on combined and free polypeptide subunits.
Biochemistry 1987;26(18):5848-53.
1987: R J Comi; N Gesundheit; L Murray; P Gorden; Bruce D Weintraub
Response of thyrotropin-secreting pituitary adenomas to a long-acting somatostatin analogue.
The New England journal of medicine 1987;317(1):12-7.
1987: P W Gyves; N Gesundheit; T Taylor; J B Butler; Bruce D Weintraub
Changes in thyrotropin (TSH) carbohydrate structure and response to TSH-releasing hormone during postnatal ontogeny: analysis by concanavalin-A chromatography.
Endocrinology 1987;121(1):133-40.
1987: M H Zweig; Gyorgy Csako; C C Benson; Bruce D Weintraub; B B Kahn
Interference by anti-immunoglobulin G antibodies in immunoradiometric assays of thyrotropin involving mouse monoclonal antibodies.
Clinical chemistry 1987;33(6):840-4.
1987: P A Dahlberg; P A Petrick; M Nissim; M M Menezes-Ferreira; Bruce D Weintraub
Intrinsic bioactivity of thyrotropin in human serum is inversely correlated with thyroid hormone concentrations. Application of a new bioassay using the FRTL-5 rat thyroid cell strain.
The Journal of clinical investigation 1987;79(5):1388-94.
1987: N Gesundheit; D L Fink; L A Silverman; Bruce D Weintraub
Effect of thyrotropin-releasing hormone on the carbohydrate structure of secreted mouse thyrotropin. Analysis by lectin affinity chromatography.
The Journal of biological chemistry 1987;262(11):5197-203.
1986: R B Constant; Bruce D Weintraub
Differences in the metabolic clearance of pituitary and serum thyrotropin (TSH) derived from euthyroid and hypothyroid rats: effects of chemical deglycosylation of pituitary TSH.
Endocrinology 1986;119(6):2720-7.
1986: J A Magner; P Petrick; M M Menezes-Ferreira; M Stelling; Bruce D Weintraub
Familial generalized resistance to thyroid hormones: report of three kindreds and correlation of patterns of affected tissues with the binding of [125I] triiodothyronine to fibroblast nuclei.
Journal of endocrinological investigation 1986;9(6):459-70.
1986: B Nilsson; S W Rosen; Bruce D Weintraub; D A Zopf
Differences in the carbohydrate moieties of the common alpha-subunits of human chorionic gonadotropin, luteinizing hormone, follicle-stimulating hormone, and thyrotropin: preliminary structural inferences from direct methylation analysis.
Endocrinology 1986;119(6):2737-43.
1986: S Amr; S S Lippman; Bruce D Weintraub
Effects of TRH on thyrotroph function and number in rat pituitaries transplanted to renal capsule.
The American journal of physiology 1986;251(5 Pt 1):E563-8.
1986: M Levine; M C Koppelman; N Patronas; Bruce D Weintraub
Amenorrhea-galactorrhea due to occult hypothyroidism.
Southern medical journal 1986;79(9):1183-4.
1986: T Taylor; N Gesundheit; Bruce D Weintraub
Effects of in vivo bolus versus continuous TRH administration on TSH secretion, biosynthesis, and glycosylation in normal and hypothyroid rats.
Molecular and cellular endocrinology 1986;46(3):253-61.
1986: N Gesundheit; J A Magner; T Chen; Bruce D Weintraub
Differential sulfation and sialylation of secreted mouse thyrotropin (TSH) subunits: regulation by TSH-releasing hormone.
Endocrinology 1986;119(2):455-63.
1986: K O Lee; N Gesundheit; H C Chen; Bruce D Weintraub
Enzymatic deglycosylation of thyroid-stimulating hormone with peptide N-glycosidase F and endo-beta-N-acetylglucosaminidase F.
Biochemical and biophysical research communications 1986;138(1):230-7.
1986: Donna Vogel; J A Magner; R J Sherins; Bruce D Weintraub
Biosynthesis, glycosylation, and secretion of rat luteinizing hormone alpha- and beta-subunits: differential effects of orchiectomy and gonadotropin-releasing hormone.
Endocrinology 1986;119(1):202-13.
1986: S S Lippman; S Amr; Bruce D Weintraub
Discordant effects of thyrotropin (TSH)-releasing hormone on pre- and posttranslational regulation of TSH biosynthesis in rat pituitary.
Endocrinology 1986;119(1):343-8.
1986: T Taylor; C W Scouten; D M Jacobowitz; Bruce D Weintraub
The effects of anterior hypothalamic deafferentation on thyrotropin (TSH) biosynthesis and response to TSH-releasing hormone.
Endocrinology 1986;118(6):2417-24.
1986: M M Menezes-Ferreira; P A Petrick; Bruce D Weintraub
Regulation of thyrotropin (TSH) bioactivity by TSH-releasing hormone and thyroid hormone.
Endocrinology 1986;118(5):2125-30.
1986: A P Weetman; D J Volkman; K D Burman; Joseph B Margolick; P Petrick; Bruce D Weintraub; Anthony Fauci
The production and characterization of thyroid-derived T-cell lines in Graves' disease and Hashimoto's thyroiditis.
Clinical immunology and immunopathology 1986;39(1):139-50.
1986: Paolo Beck-Peccoz; G Piscitelli; S Amr; M Ballabio; M Bassetti; G Giannattasio; Anna Spada; M Nissim; Bruce D Weintraub; G Faglia
Endocrine, biochemical, and morphological studies of a pituitary adenoma secreting growth hormone, thyrotropin (TSH), and alpha-subunit: evidence for secretion of TSH with increased bioactivity.
The Journal of clinical endocrinology and metabolism 1986;62(4):704-11.
1986: R O Hussa; HENRY FEIN; R A Pattillo; S B Nagelberg; S W Rosen; Bruce D Weintraub; F Perini; RW Ruddon; L A Cole
A distinctive form of human chorionic gonadotropin beta-subunit-like material produced by cervical carcinoma cells.
Cancer research 1986;46(4 Pt 2):1948-54.
1986: N Gesundheit; Bruce D Weintraub
Mechanisms and regulation of TSH glycosylation.
Advances in experimental medicine and biology 1986;205():87-105.
1985: S B Nagelberg; J Burnside; A Maniatis; S S Lippman; Bruce D Weintraub
Pretranslational regulation of ectopic hCG alpha production in ChaGo lung cancer cells by sodium butyrate.
Biochemical and biophysical research communications 1985;133(3):972-80.
1985: S Amr; M Menezez-Ferreira; Y Shimohigashi; H C Chen; B Nisula; Bruce D Weintraub
Activities of deglycosylated thyrotropin at the thyroid membrane receptor-adenylate cyclase system.
Journal of endocrinological investigation 1985;8(6):537-41.
1985: J Burnside; S B Nagelberg; S S Lippman; Bruce D Weintraub
Differential regulation of hCG alpha and beta subunit mRNAs in JEG-3 choriocarcinoma cells by 8-bromo-cAMP.
The Journal of biological chemistry 1985;260(23):12705-9.
1985: C Ronin; Bethel Stannard; Bruce D Weintraub
Differential processing and regulation of thyroid-stimulating hormone subunit carbohydrate chains in thyrotropic tumors and in normal and hypothyroid pituitaries.
Biochemistry 1985;24(20):5626-31.
1985: I S Calvert; Bruce D Weintraub; L Panton; L Gaffney; S W Rosen
Eutopic and ectopic macromolecular human placental lactogen.
American journal of obstetrics and gynecology 1985;152(1):103-11.
1985: T Taylor; Bruce D Weintraub
Thyrotropin (TSH)-releasing hormone regulation of TSH subunit biosynthesis and glycosylation in normal and hypothyroid rat pituitaries.
Endocrinology 1985;116(5):1968-76.
1985: Paolo Beck-Peccoz; S Amr; M M Menezes-Ferreira; G Faglia; Bruce D Weintraub
Decreased receptor binding of biologically inactive thyrotropin in central hypothyroidism. Effect of treatment with thyrotropin-releasing hormone.
The New England journal of medicine 1985;312(17):1085-90.
1985: T Taylor; Bruce D Weintraub
Differential regulation of thyrotropin subunit apoprotein and carbohydrate biosynthesis by thyroid hormone.
Endocrinology 1985;116(4):1535-42.
1985: Bruce D Weintraub; Bethel Stannard; J A Magner; C Ronin; T Taylor; L Joshi; R B Constant; M M Menezes-Ferreira; P Petrick; N Gesundheit
Glycosylation and posttranslational processing of thyroid-stimulating hormone: clinical implications.
Recent progress in hormone research 1985;41():577-606.
1984: M M Menezes-Ferreira; C Eil; J Wortsman; Bruce D Weintraub
Decreased nuclear uptake of [125I]triiodo-L-thyronine in fibroblasts from patients with peripheral thyroid hormone resistance.
The Journal of clinical endocrinology and metabolism 1984;59(6):1081-7.
1984: Philippe Jaquet; J Hassoun; P Delori; Ginette Gunz; F Grisoli; Bruce D Weintraub
A human pituitary adenoma secreting thyrotropin and prolactin: immunohistochemical, biochemical, and cell culture studies.
The Journal of clinical endocrinology and metabolism 1984;59(5):817-24.
1984: Y R Jones-Brown; C Y Wu; Bruce D Weintraub; S W Rosen
Synthesis of chorionic gonadotropin subunits in human choriocarcinoma clonal cell line JEG-3: carbohydrate differences in glycopeptides from free and combined alpha-subunits.
Endocrinology 1984;115(4):1439-45.
1984: C Ronin; Bethel Stannard; I L Rosenbloom; J A Magner; Bruce D Weintraub
Glycosylation and processing of high-mannose oligosaccharides of thyroid-stimulating hormone subunits: comparison to nonsecretory cell glycoproteins.
Biochemistry 1984;23(20):4503-10.
1984: J A Magner; C Ronin; Bruce D Weintraub
Carbohydrate processing of thyrotropin differs from that of free alpha-subunit and total glycoproteins in microsomal subfractions of mouse pituitary tumor.
Endocrinology 1984;115(3):1019-30.
1983: L R Joshi; Bruce D Weintraub
Naturally occurring forms of thyrotropin with low bioactivity and altered carbohydrate content act as competitive antagonists to more bioactive forms.
Endocrinology 1983;113(6):2145-54.
1983: J S Morrow; Bruce D Weintraub; S W Rosen
Butyrate regulates glycosylation of the glycoprotein hormone alpha subunit secreted by "glucose-starved" human liver cells.
Biochemical and biophysical research communications 1983;112(1):115-25.
1983: Bruce D Weintraub; B S Stannard; L Meyers
Glycosylation of thyroid-stimulating hormone in pituitary tumor cells: influence of high mannose oligosaccharide units on subunit aggregation, combination, and intracellular degradation.
Endocrinology 1983;112(4):1331-45.
1982: C Eil; HENRY FEIN; T J Smith; R W Furlanetto; M Bourgeois; M W Stelling; Bruce D Weintraub
Nuclear binding of [125I]triiodothyronine in dispersed cultured skin fibroblasts from patients with resistance to thyroid hormone.
The Journal of clinical endocrinology and metabolism 1982;55(3):502-10.
1982: J M Goldman; Bruce D Weintraub
Recovery of pituitary secretion of thyrotropin and its free alpha- and beta-subunits after triiodothyronine withdrawal.
The Journal of clinical endocrinology and metabolism 1982;55(2):337-40.
1982: J A Magner; Bruce D Weintraub
Thyroid-stimulating hormone subunit processing and combination in microsomal subfractions of mouse pituitary tumor.
The Journal of biological chemistry 1982;257(12):6709-15.
1982: J L Stock; Bruce D Weintraub; S W Rosen; G D Aurbach; Allen Spiegel; S J Marx
Human chorionic gonadotropin subunit measurement in primary hyperparathyroidism.
The Journal of clinical endocrinology and metabolism 1982;54(1):57-63.
1981: F Pekonen; P Carayon; S Amr; Bruce D Weintraub
Heterogeneous forms of thyroid-stimulating hormone in mouse thyrotropic tumor and serum: differences in receptor-binding and adenylate cyclase-stimulating activity.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1981;13(11):617-20.
1981: Marc R Blackman; Bruce D Weintraub; I A Kourides; J T Solano; T Santner; S W Rosen
Discordant elevation of the common alpha-subunit of the glycoprotein hormones compared to beta-subunits in serum of uremic patients.
The Journal of clinical endocrinology and metabolism 1981;53(1):39-48.
1981: Bruce D Weintraub
Hormone markers for cancer.
Medical times 1981;109(5):37-9.
1981: T H Shawker; M R Paling; Bruce D Weintraub
Dysphagia due to thyroid immobilization: value of real-time sonography.
AJR. American journal of roentgenology 1981;136(3):601-2.
1981: M C Marshall; D Williams; Bruce D Weintraub
Regulation of de novo biosynthesis of thyrotropin in normal, hyperplastic, and neoplastic thyrotrophs.
Endocrinology 1981;108(3):908-15.
1981: I M Spitz; D Le Roith; H Hirsch; P Carayon; F Pekonen; Y Liel; R Sobel; Z Chorer; Bruce D Weintraub
Increased high-molecular-weight thyrotropin with impaired biologic activity in a euthyroid man.
The New England journal of medicine 1981;304(5):278-82.
1980: J Karsh; N Pavlidis; Bruce D Weintraub; H M Moutsopoulos
Thyroid disease in Sjögren's syndrome.
Arthritis and rheumatism 1980;23(11):1326-9.
1980: HENRY FEIN; J M Goldman; Bruce D Weintraub
Postpartum lymphocytic thyroiditis in American women: a spectrum of thyroid dysfunction.
American journal of obstetrics and gynecology 1980;138(5):504-10.
1980: S W Rosen; I Calvert; Bruce D Weintraub; J S Tseng; A S Rabson
Stimulation of N6,O2'-dibutyryl cyclic adenosine 3':5'-monophosphate of ectopic production of the free beta subunit of chorionic gonadotropin by a human brain tumor cell line.
Cancer research 1980;40(11):4325-8.
1980: F Pekonen; Bruce D Weintraub
Salt-induced exposure of high affinity thyrotropin receptors on human and porcine thyroid membranes.
The Journal of biological chemistry 1980;255(17):8121-7.
1980: I A Kourides; F Pekonen; Bruce D Weintraub
Absence of thyroid-binding immunoglobulins in patients with thyrotropin-mediated hyperthyroidism.
The Journal of clinical endocrinology and metabolism 1980;51(2):272-4.
1980: Marc R Blackman; Bruce D Weintraub; S W Rosen; I A Kourides; K Steinwascher; M H Gail
Human placental and pituitary glycoprotein hormones and their subunits as tumor markers: a quantitative assessment.
Journal of the National Cancer Institute 1980;65(1):81-93.
1980: Bruce D Weintraub; B S Stannard; D Linnekin; M Marshall
Relationship of glycosylation to de novo thyroid-stimulating hormone biosynthesis and secretion by mouse pituitary tumor cells.
The Journal of biological chemistry 1980;255(12):5715-23.
1980: HENRY FEIN; S W Rosen; Bruce D Weintraub
Increased glycosylation of serum human chorionic gonadotropin and subunits from eutopic and ectopic sources: comparison with placental and urinary forms.
The Journal of clinical endocrinology and metabolism 1980;50(6):1111-20.
1980: F Pekonen; D M Williams; Bruce D Weintraub
Purification of thyrotropin and other glycoprotein hormones by immunoaffinity chromatography.
Endocrinology 1980;106(5):1327-32.
1980: S W Rosen; Bruce D Weintraub; S A Aaronson
Nonrandom ectopic protein production by malignant cells: direct evidence in vitro.
The Journal of clinical endocrinology and metabolism 1980;50(5):834-41.
1980: I A Kourides; M B Landon; B J Hoffman; Bruce D Weintraub
Excess free alpha relative to beta subunits of the glycoprotein hormones in normal and abnormal human pituitary glands.
Clinical endocrinology 1980;12(4):407-16.
1980: D J Dean; Bruce D Weintraub; S W Rosen
De novo synthesis and secretion of heterogeneous forms of human chorionic gonadotropin and its free alpha-subunit in the human choriocarcinoma clonal cell line JEG-3.
Endocrinology 1980;106(3):849-58.
1980: P D Neuwald; C Anderson; W O Salivar; P H Aldenderfer; W C Dermody; Bruce D Weintraub; S W Rosen; W A Nelson-Rees; R W Ruddon
Expression of oncodevelopmental gene products by human tumor cells in culture.
Journal of the National Cancer Institute 1980;64(3):447-59.
1980: F Pekonen; Bruce D Weintraub
Interaction of crude and pure chorionic gonadotropin with the thyrotropin receptor.
The Journal of clinical endocrinology and metabolism 1980;50(2):280-5.
1980: Bruce D Weintraub; S W Rosen
Case 35-1979: factitious illness.
The New England journal of medicine 1980;302(4):237.
1980: T A Hamilton; A W Tin; H H Sussman; Bruce D Weintraub; S W Rosen
Independent expression of alpha-HCG and placental alkaline phosphatase in clonal human cell lines.
Oncodevelopmental biology and medicine : the journal of the International Society for Oncodevelopmental Biology and Medicine 1980;1(3):161-7.
1979: L C Giudice; Bruce D Weintraub
Evidence for conformational differences between precursor and processed forms of thyroid-stimulating hormone beta subunit.
The Journal of biological chemistry 1979;254(24):12679-83.
1979: L C Giudice; M J Waxdal; Bruce D Weintraub
Comparison of bovine and mouse pituitary glycoprotein hormone pre-alpha subunits synthesized in vitro.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(10):4798-802.
1979: F Pekonen; Bruce D Weintraub
Thyrotropin receptors on bovine thyroid membranes: two types with different affinities and specificities.
Endocrinology 1979;105(2):352-9.
1979: G S Cox; Bruce D Weintraub; S W Rosen; C Krutzsch; I Stotler; E S Maxwell
High molecular weight forms of human placental lactogen: synthesis in vitro and binding to membrane receptors for lactogenic hormones.
Archives of biochemistry and biophysics 1979;193(2):355-67.
1979: R A Bender; Bruce D Weintraub; S W Rosen
Prospective evaluation of two tumor-associated proteins in pancreatic adenocarcinoma.
Cancer 1979;43(2):591-5.
1979: I A Kourides; Bruce D Weintraub
mRNA-directed biosynthesis of alpha subunit of thyrotropin: translation in cell-free and whole-cell systems.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(1):298-302.
1979: T S Tralka; S W Rosen; Bruce D Weintraub; J M Lieblich; L W Engel; B K Wetzel; E W Kingsbury; A S Rabson
Ultrastructural concomitants of sodium butyrate-enhanced ectopic production of chorionic gonadotropin and its alpha subunit human bronchogenic carcinoma (ChaGo) cells.
Journal of the National Cancer Institute 1979;62(1):45-61.
1978: I A Kourides; Bruce D Weintraub; R N Re; E C Ridgway; F Maloof
Thyroid hormone, oestrogen, and glucocorticoid effects on two different pituitary glycoprotein hormone alpha subunit pools.
Clinical endocrinology 1978;9(6):535-42.
1978: F Pekonen; Bruce D Weintraub
Thyrotropin binding to cultured lymphocytes and thyroid cells.
Endocrinology 1978;103(5):1668-77.
1978: Bruce D Weintraub; B S Stannard
Precursor-product relationships in the biosynthesis and secretion of thyrotropin and its subunits by mouse thyrotropic tumor cells.
FEBS letters 1978;92(2):303-7.
1978: L E Broder; Bruce D Weintraub; S W Rosen
Influence of chemotherapeutic agents on chorionic gonadotropin-alpha subunit secretion in a human lung cancer cell line (ChaGo): discordance of cytotoxic and secretory effects.
Journal of the National Cancer Institute 1978;61(2):349-51.
1978: S A Metz; Bruce D Weintraub; S W Rosen; J Singer; R P Robertson
Ectopic secretion of chorionic gonadotropin by a lung carcinoma. Pituitary gonadotropin and subunit secretion and prolonged chemotherapeutic remission.
The American journal of medicine 1978;65(2):325-33.
1978: I A Kourides; Bruce D Weintraub; F Maloof
Large molecular weight TSH-beta: the sole immunoactive form of TSH-beta in certain human sera.
The Journal of clinical endocrinology and metabolism 1978;47(1):24-33.
1978: Allen Spiegel; S W Rosen; Bruce D Weintraub; S P Marynick
Effect of intravenous pyridoxine on plasma prolactin in hyperprolactinemic subjects.
The Journal of clinical endocrinology and metabolism 1978;46(4):686-8.
1978: Marc R Blackman; M C Gershengorn; Bruce D Weintraub
Excess production of free alpha subunits by mouse pituitary thyrotropic tumor cells in vitro.
Endocrinology 1978;102(2):499-508.
1978: Marc R Blackman; S W Rosen; Bruce D Weintraub
Ectopic hormones.
Advances in internal medicine 1978;23():85-113.
1978: M Danon; Bruce D Weintraub; S H Kim; R E Scully; J D Crawford
Sexual precocity in a male due to thoracic polyembryoma.
The Journal of pediatrics 1978;92(1):51-4.
1977: J M Lieblich; S W Rosen; Bruce D Weintraub; W F Sindelar; T S Tralka; A S Rabson
Maintenance of ectopic chorionic gonadotropin and alpha subunit secretion by a human lung cancer cell line (ChaGo) transplanted into nude mice.
Journal of the National Cancer Institute 1977;59(4):1285-9.
1977: C R Kahn; S W Rosen; Bruce D Weintraub; SS Fajans; P Gorden
Ectopic production of chorionic gonadotropin and its subunits by islet-cell tumors. A specific marker for malignancy.
The New England journal of medicine 1977;297(11):565-9.
1977: M C Gershengorn; M R McClung; E W Chu; T A Hanson; Bruce D Weintraub; J Robbins
Fine-needle aspiration cytology in the preoperative diagnosis of thyroid nodules.
Annals of internal medicine 1977;87(3):265-9.
1977: I A Kourides; E C Ridgway; Bruce D Weintraub; S T Bigos; M C Gershengorn; F Maloof
Thyrotropin-induced hyperthyroidism: use of alpha and beta subunit levels to identify patients with pituitary tumors.
The Journal of clinical endocrinology and metabolism 1977;45(3):534-43.
1977: L E Broder; Bruce D Weintraub; S W Rosen; M H Cohen; F Tejada
Placental proteins and their subunits as tumor markers in prostatic carcinoma.
Cancer 1977;40(1):211-6.
1977: Bruce D Weintraub; B S Stannard; S W Rosen
Combination of ectopic and standard human glycoprotein hormone alpha with beta subunits: discordance of immunologic and receptor-binding activity.
Endocrinology 1977;101(1):225-35.
1977: I A Kourides; R N Re; Bruce D Weintraub; E C Ridgway; F Maloof
Metabolic clearance and secretion rates of subunits of human thyrotropin.
The Journal of clinical investigation 1977;59(3):508-16.
1977: J M Lieblich; Bruce D Weintraub; S W Rosen; N K Ghosh; R P Cox
Secretion of hCG-alpha subunit and hCG by HeLa strains.
Nature 1977;265(5596):746.
1976: I A Kourides; Bruce D Weintraub; M A Martorana; F Maloof
Alpha subunit contamination of human albumin preparations: interference in radioimmunoassy.
The Journal of clinical endocrinology and metabolism 1976;43(4):919-23.
1976: R N Re; I A Kourides; E C Ridgway; Bruce D Weintraub; F Maloof
The effect of glucocorticoid administration on human pituitary secretion of thyrotropin and prolactin.
The Journal of clinical endocrinology and metabolism 1976;43(2):338-46.
1976: J Y Chou; Bruce D Weintraub; S W Rosen; J Whangpeng; H D Sussman; J R Haughom; J C Robinson
Synthesis of alpha subunit of human chorionic gonadotrophin by presumptive HeLa cells.
In vitro 1976;12(8):589-94.
1976: I A Kourides; Bruce D Weintraub; S W Rosen; E C Ridgway; B Kliman; F Maloof
Secretion of alpha subunit of glycoprotein hormones by pituitary adenomas.
The Journal of clinical endocrinology and metabolism 1976;43(1):97-106.
1976: J M Lieblich; Bruce D Weintraub; G H Krauth; Peter O Kohler; A S Rabson; S W Rosen
Ectopic and eutopic secretion of chorionic gonadotropin and its sub-nits in vitro: comparison of clonal strains from carcinomas of lung and placenta.
Journal of the National Cancer Institute 1976;56(5):911-7.
1976: K C Ingham; Bruce D Weintraub; H Edelhock
Kinetics of recombination of the subunits of human chorionic gonadotropin. Effect of subunit concentration.
Biochemistry 1976;15(8):1720-6.
1976: J M Lieblich; Bruce D Weintraub; S W Rosen; J Y Chou; J C Robinson
HeLa cells secrete alpha subunit of glycoprotein tropic hormones.
Nature 1976;260(5551):530-2.
1976: G S Cox; Bruce D Weintraub; S W Rosen; E S Maxwell
Properties of biologically active messenger RNA from human placenta. Cell-free synthesis of two immunoreactive forms of placental lactogen.
The Journal of biological chemistry 1976;251(6):1723-30.
1975: Bruce D Weintraub; G Krauth; S W Rosen; A S Babson
Differences between purified ectopic and normal alpha subnits of human glycoprotein hormones.
The Journal of clinical investigation 1975;56(4):1043-52.
1975: F M Muggia; S W Rosen; Bruce D Weintraub; H H Hansen
Ectopic placental proteins in nontrophoblastic tumors. Serial measurements following chemotherapy.
Cancer 1975;36(4):1327-37.
1975: M C Gershengorn; Bruce D Weintraub
Thyrotropin-induced hyperthyroidism caused by selective pituitary resistance to thyroid hormone. A new syndrome of "inappropriate secretion of TSH".
The Journal of clinical investigation 1975;56(3):633-42.
1975: I A Kourides; Bruce D Weintraub; E C Ridgway; F Maloof
Pituitary secretion of free alpha and beta subunit of human thyrotropin in patients with thyroid disorders.
The Journal of clinical endocrinology and metabolism 1975;40(5):872-85.
1975: S W Rosen; Bruce D Weintraub
Humours, tumors, and caveats.
Annals of internal medicine 1975;82(2):274-6.
1974: E C Ridgway; F R Singer; Bruce D Weintraub; L Lorenz; F Maloof
Metabolism of human thyrotropin in the dog.
Endocrinology 1974;95(4):1181-5.
1974: J D Kieffer; Bruce D Weintraub; W Baigelman; S Leeman; F Maloof
Homologous radioimmunoassay of thyrotrophin in rat plasma.
Acta endocrinologica 1974;76(3):495-505.
1974: S W Rosen; Bruce D Weintraub
Ectopic production of the isolated alpha subunit of the glycoprotein hormones. A quantitative marker in certain cases of cancer.
The New England journal of medicine 1974;290(26):1441-7.
1974: K M Gautvik; A H Tashjian; I A Kourides; Bruce D Weintraub; C T Graeber; F Maloof; K Suzuki; J E Zuckerman
Thyrotropin-releasing hormone is not the sole physiologic mediator of prolactin release during suckling.
The New England journal of medicine 1974;290(21):1162-5.
1974: I A Kourides; Bruce D Weintraub; M A Levko; F Maloof
Alpha and beta subunits of human thyrotropin: purification and development of specific radioimmunoassays.
Endocrinology 1974;94(5):1411-21.
1974: D W Golde; M Schambelan; Bruce D Weintraub; S W Rosen
Gonadotropin-secreting renal carcinoma.
Cancer 1974;33(4):1048-53.
1974: H H Sussman; Bruce D Weintraub; S W Rosen
Relationship of ectopic placental alkaline phosphatase to ectopic chorionic gonadotropin and placental lactogen. Discordance of three "markers" for cancer.
Cancer 1974;33(3):820-3.
1974: E C Ridgway; Bruce D Weintraub; F Maloof
Metabolic clearance and production rates of human thyrotropin.
The Journal of clinical investigation 1974;53(3):895-903.
1973: Bruce D Weintraub; S W Rosen
Ectopic production of the isolated beta subunit of human chorionic gonadotropin.
The Journal of clinical investigation 1973;52(12):3135-42.
1973: I A Kourides; Bruce D Weintraub; E C Ridgway; F Maloof
Increase in the beta subunit of human TSH in hypothyroid serum after thyrotropin releasing hormone.
The Journal of clinical endocrinology and metabolism 1973;37(5):836-40.
1973: E C Ridgway; Bruce D Weintraub; J L Cevallos; M C Rack; F Maloof
Suppression of pituitary TSH secretion in the patient with a hyperfunctioning thyroid nodule.
The Journal of clinical investigation 1973;52(11):2783-92.
1973: M A Charles; R Claypool; M Schaaf; S W Rosen; Bruce D Weintraub
Lung carcinoma associated with production of three placental proteins. Ectopic human chorionic gonadotropin, human chorionic somatomammotropin, and placental alkaline phosphatase.
Archives of internal medicine 1973;132(3):427-31.
1973: Bruce D Weintraub; S W Rosen
Competitive radioassays and "specific" tumor markers.
Metabolism: clinical and experimental 1973;22(8):1119-27.
1973: K M Gautvik; Bruce D Weintraub; C T Graeber; F Maloof; J E Zuckerman; A H Tashjian
Serum prolactin and TSH: effects of nursing and pyroGlu-His-ProNH2 administration in postpartum women.
The Journal of clinical endocrinology and metabolism 1973;37(1):135-9.
1973: A H Tashjian; Bruce D Weintraub; N J Barowsky; A S Rabson; S W Rosen
Subunits of human chorionic gonadotropin: unbalanced synthesis and secretion by clonal cell strains derived from a bronchogenic carcinoma.
Proceedings of the National Academy of Sciences of the United States of America 1973;70(5):1419-22.
1973: Bruce D Weintraub; S W Rosen; J A McCammon; R L Perlman
Apparent cooperativity in radioimmunoassay of human chorionic gonadotropin.
Endocrinology 1973;92(4):1250-5.
1973: H H Bode; M Danon; Bruce D Weintraub; F Maloof; J D Crawford
Partial target organ resistance to thyroid hormone.
The Journal of clinical investigation 1973;52(4):776-82.
1973: A S Rabson; S W Rosen; A H Tashijan; Bruce D Weintraub
Production of human chorionic gonadotropin in vitro by a cell line derived from a carcinoma of the lung.
Journal of the National Cancer Institute 1973;50(3):669-74.
1971: Bruce D Weintraub; Y M Kadesky
Fractionation of antibodies to human chorionic somatomammotropin: application to radioimmunoassay.
The Journal of clinical endocrinology and metabolism 1971;33(3):432-5.
1971: S W Rosen; Bruce D Weintraub
Monotropic increase of serum FSH correlated with low sperm count in young men with idiopathic oligospermia and aspermia.
The Journal of clinical endocrinology and metabolism 1971;32(3):410-6.
1971: Bruce D Weintraub; S W Rosen
Ectopic production of human chorionic somatomammotropin by nontrophoblastic cancers.
The Journal of clinical endocrinology and metabolism 1971;32(1):94-101.
1970: Bruce D Weintraub
Concentration and purification of human chorionic somato-mammotropin (HCS) by affinity chromatography: application to radioimmunoassay.
Biochemical and biophysical research communications 1970;39(1):83-9.