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Thomas Weiser

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TOP 3
Wolfram Gaida; Klaus Klinder; Kirsten Arndt; Thomas Weiser
Ambroxol, a Nav1.8-preferring Na(+) channel blocker, effectively suppresses pain symptoms in animal models of chronic, neuropathic and inflammatory pain.
Jerry J Buccafusco; Thomas Weiser; Karin Winter; Klaus Klinder; Alvin V Terry
The effects of IDRA 21, a positive modulator of the AMPA receptor, on delayed matching performance by young and aged rhesus monkeys.
Matthias Grauert; Wolf D Bechtel; Thomas Weiser; Werner Stransky; Herbert Nar; Adrian J Carter
Synthesis and structure-activity relationships of 6,7-benzomorphan derivatives as use-dependent sodium channel blockers for the treatment of stroke.

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All Publications

2005: Wolfram Gaida; Klaus Klinder; Kirsten Arndt; Thomas Weiser
Ambroxol, a Nav1.8-preferring Na(+) channel blocker, effectively suppresses pain symptoms in animal models of chronic, neuropathic and inflammatory pain.
Neuropharmacology 2005;49(8):1220-7.
2004: Jerry J Buccafusco; Thomas Weiser; Karin Winter; Klaus Klinder; Alvin V Terry
The effects of IDRA 21, a positive modulator of the AMPA receptor, on delayed matching performance by young and aged rhesus monkeys.
Neuropharmacology 2004;46(1):10-22.
2002: Matthias Grauert; Wolf D Bechtel; Thomas Weiser; Werner Stransky; Herbert Nar; Adrian J Carter
Synthesis and structure-activity relationships of 6,7-benzomorphan derivatives as use-dependent sodium channel blockers for the treatment of stroke.
Journal of medicinal chemistry 2002;45(17):3755-64.
2001: Marion Wienrich; M Brenner; W Löscher; R Palluk; M Pieper; H Potschka; Thomas Weiser
In vivo pharmacology of BIIR 561 CL, a novel combined antagonist of AMPA receptors and voltage-dependent Na(+) channels.
British journal of pharmacology 2001;133(6):789-96.
2001: Thomas Weiser; Marion Wienrich; M Brenner; R Kubiak; G Weckesser; R Palluk
The AMPA receptor/Na(+) channel blocker BIIR 561 CL is protective in a model of global cerebral ischaemia.
European journal of pharmacology 2001;421(3):165-70.
2000: Thomas Weiser; M Iizuka; S Nishimura; I Akiba; Edward L Barsoumian; M Zhou; Christian Steinhäuser; M Brenner; R Palluk; Marion Wienrich
Characterization of the anticonvulsant and neuroprotectant BIIR 561 CL in vitro: effects on native and recombinant alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors.
Naunyn-Schmiedeberg's archives of pharmacology 2000;362(4-5):419-26.
2000: Adrian J Carter; Matthias Grauert; U Pschorn; Wolf D Bechtel; C Bartmann-Lindholm; Yusheng Qu; Todd Scheuer; William A Catterall; Thomas Weiser
Potent blockade of sodium channels and protection of brain tissue from ischemia by BIII 890 CL.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(9):4944-9.
2000: Gerald Seifert; M Zhou; Dirk Dietrich; TB Schumacher; A Dybek; Thomas Weiser; Marion Wienrich; D Wilhelm; Christian Steinhäuser
Developmental regulation of AMPA-receptor properties in CA1 pyramidal neurons of rat hippocampus.
Neuropharmacology 2000;39(6):931-42.
1999: Thomas Weiser; Yusheng Qu; William A Catterall; Todd Scheuer
Differential interaction of R-mexiletine with the local anesthetic receptor site on brain and heart sodium channel alpha-subunits.
Molecular pharmacology 1999;56(6):1238-44.
1999: Thomas Weiser; M Brenner; R Palluk; Wolf D Bechtel; A Ceci; A Brambilla; Helmut A Ensinger; A Sagrada; Marion Wienrich
BIIR 561 CL: a novel combined antagonist of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors and voltage-dependent sodium channels with anticonvulsive and neuroprotective properties.
The Journal of pharmacology and experimental therapeutics 1999;289(3):1343-9.
1999: Henning Draheim; M Prinz; Joerg R Weber; Thomas Weiser; H Kettenmann; Uwe-Karsten Hanisch
Induction of potassium channels in mouse brain microglia: cells acquire responsiveness to pneumococcal cell wall components during late development.
Neuroscience 1999;89(4):1379-90.
1997: C Berger; S Reinhardt; M Rentrop; M Bachmann; Thomas Weiser; E Link; Marion Wienrich; R Jahn; Alfred Maelicke
De novo acquisition of neuronal polarity in retinoic acid-induced embryonal carcinoma cells.
European journal of cell biology 1997;74(3):230-45.
1996: Thomas Weiser; Marion Wienrich
The effects of copper ions on glutamate receptors in cultured rat cortical neurons.
Brain research 1996;742(1-2):211-8.
1996: Thomas Weiser; A Herrmann; Marion Wienrich
Interactions of the dye Evans Blue and GYKI 52466, a 2,3-benzodiazepine, with (S)- alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors in cultured rat cortical neurons: electrophysiological evidence for at least two different binding sites for non-competitive antagonists.
Neuroscience letters 1996;216(1):29-32.
1996: Thomas Weiser; Marion Wienrich
Investigations on the mechanism of action of the antiproliferant and ion channel antagonist flufenamic acid.
Naunyn-Schmiedeberg's archives of pharmacology 1996;353(4):452-60.
1994: Olaf Strauss; Thomas Weiser; Marion Wienrich
Potassium currents in cultured cells of the rat retinal pigment epithelium.
Comparative biochemistry and physiology. Part A, Physiology 1994;109(4):975-83.