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Irving Weissman

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Inlay Matthew A; Bhattacharya Deepta; Sahoo Debashis; Serwold Thomas; Seita Jun; Karsunky Holger; Plevritis Sylvia K; Dill David L; Weissman Irving L
Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development.
Papathanasiou Peter; Attema Joanne L; Karsunky Holger; Xu Jian; Smale Stephen T; Weissman Irving L
Evaluation of the long-term reconstituting subset of hematopoietic stem cells with CD150.
Yamada Mayumi; Gurney Paul T; Chung Jaehoon; Kundu Pratima; Drukker Micha; Smith Alan K; Weissman Irving L; Nishimura Dwight; Robbins Robert C; Yang Phillip C
Manganese-guided cellular MRI of human embryonic stem cell and human bone marrow stromal cell viability.

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All Publications

2009: Inlay Matthew A; Bhattacharya Deepta; Sahoo Debashis; Serwold Thomas; Seita Jun; Karsunky Holger; Plevritis Sylvia K; Dill David L; Weissman Irving L
Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development.
Genes & development 2009;23(20):2376-81.
2009: Papathanasiou Peter; Attema Joanne L; Karsunky Holger; Xu Jian; Smale Stephen T; Weissman Irving L
Evaluation of the long-term reconstituting subset of hematopoietic stem cells with CD150.
Stem cells (Dayton, Ohio) 2009;27(10):2498-508.
2009: Yamada Mayumi; Gurney Paul T; Chung Jaehoon; Kundu Pratima; Drukker Micha; Smith Alan K; Weissman Irving L; Nishimura Dwight; Robbins Robert C; Yang Phillip C
Manganese-guided cellular MRI of human embryonic stem cell and human bone marrow stromal cell viability.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2009;62(4):1047-54.
2009: Jaiswal Siddhartha; Weissman Irving L
Hematopoietic stem and progenitor cells and the inflammatory response.
Annals of the New York Academy of Sciences 2009;1174():118-21.
2009: Chan Keith Syson; Espinosa Inigo; Chao Mark; Wong David; Ailles Laurie; Diehn Max; Gill Harcharan; Presti Joseph; Chang Howard Y; van de Rijn Matt; Shortliffe Linda; Weissman Irving L
Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(33):14016-21.
2009: Cheshier Samuel H; Kalani M Yashar S; Lim Michael; Ailles Laurie; Huhn Steven L; Weissman Irving L
A neurosurgeon's guide to stem cells, cancer stem cells, and brain tumor stem cells.
Neurosurgery 2009;65(2):237-49; discussion 249-50; quiz N6.
2009: Majeti Ravindra; Chao Mark P; Alizadeh Ash A; Pang Wendy W; Jaiswal Siddhartha; Gibbs Kenneth D; van Rooijen Nico; Weissman Irving L
CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells.
Cell 2009;138(2):286-99.
2009: Jaiswal Siddhartha; Jamieson Catriona H M; Pang Wendy W; Park Christopher Y; Chao Mark P; Majeti Ravindra; Traver David; van Rooijen Nico; Weissman Irving L
CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis.
Cell 2009;138(2):271-85.
2009: Yamane Toshiyuki; Hosen Naoki; Yamazaki Hidetoshi; Weissman Irving L
Expression of AA4.1 marks lymphohematopoietic progenitors in early mouse development.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(22):8953-8.
2009: Ootani Akifumi; Li Xingnan; Sangiorgi Eugenio; Ho Quoc T; Ueno Hiroo; Toda Shuji; Sugihara Hajime; Fujimoto Kazuma; Weissman Irving L; Capecchi Mario R; Kuo Calvin J
Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche.
Nature medicine 2009;15(6):701-6.
2009: Wu Angela R; Hiatt Joseph B; Lu Rong; Attema Joanne L; Lobo Neethan A; Weissman Irving L; Clarke Michael F; Quake Stephen R
Automated microfluidic chromatin immunoprecipitation from 2,000 cells.
Lab on a chip 2009;9(10):1365-70.
2009: Diehn Maximilian; Cho Robert W; Lobo Neethan A; Kalisky Tomer; Dorie Mary Jo; Kulp Angela N; Qian Dalong; Lam Jessica S; Ailles Laurie E; Wong Manzhi; Joshua Benzion; Kaplan Michael J; Wapnir Irene; Dirbas Frederick M; Somlo George; Garberoglio Carlos; Paz Benjamin; Shen Jeannie; Lau Sean K; Quake Stephen R; Brown J Martin; Weissman Irving L; Clarke Michael F
Association of reactive oxygen species levels and radioresistance in cancer stem cells.
Nature 2009;458(7239):780-3.
2009: Abrahamsson Annelie E; Geron Ifat; Gotlib Jason; Dao Kim-Hien T; Barroga Charlene F; Newton Isabel G; Giles Francis J; Durocher Jeffrey; Creusot Remi S; Karimi Mobin; Jones Carol; Zehnder James L; Keating Armand; Negrin Robert S; Weissman Irving L; Jamieson Catriona H M
Glycogen synthase kinase 3beta missplicing contributes to leukemia stem cell generation.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(10):3925-9.
2009: Majeti Ravindra; Becker Michael W; Tian Qiang; Lee Tsung-Lu Michael; Yan Xiaowei; Liu Rui; Chiang Jung-Hsien; Hood Leroy; Clarke Michael F; Weissman Irving L
Dysregulated gene expression networks in human acute myelogenous leukemia stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(9):3396-401.
2009: Ooi A G Lisa; Karsunky Holger; Majeti Ravindra; Butz Stefan; Vestweber Dietmar; Ishida Tatsuro; Quertermous Thomas; Weissman Irving L; Forsberg E Camilla
The adhesion molecule esam1 is a novel hematopoietic stem cell marker.
Stem cells (Dayton, Ohio) 2009;27(3):653-61.
2009: Xie Xiaoyan; Chan Keith S; Cao Feng; Huang Mei; Li Zongjin; Lee Andrew; Weissman Irving L; Wu Joseph C
Imaging of STAT3 signaling pathway during mouse embryonic stem cell differentiation.
Stem cells and development 2009;18(2):205-14.
2009: Semerad Craig L; Mercer Elinore M; Inlay Matthew A; Weissman Irving L; Murre Cornelis
E2A proteins maintain the hematopoietic stem cell pool and promote the maturation of myelolymphoid and myeloerythroid progenitors.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(6):1930-5.
2009: Park Christopher Y; Tseng Diane; Weissman Irving L
Cancer stem cell-directed therapies: recent data from the laboratory and clinic.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(2):219-30.
2009: Ueno Hiroo; Turnbull Brit B; Weissman Irving L
Two-step oligoclonal development of male germ cells.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(1):175-80.
2009: Chan Charles K F; Chen Ching-Cheng; Luppen Cynthia A; Kim Jae-Beom; DeBoer Anthony T; Wei Kevin; Helms Jill A; Kuo Calvin J; Kraft Daniel L; Weissman Irving L
Endochondral ossification is required for haematopoietic stem-cell niche formation.
Nature 2009;457(7228):490-4.
2009: Serwold Thomas; Ehrlich L I R; Weissman Irving L
Reductive isolation from bone marrow and blood implicates common lymphoid progenitors as the major source of thymopoiesis.
Blood 2009;113(4):807-15.
2008: Suzuki Yoriyasu; Cunningham Charle H; Noguchi Ken-ichiro; Chen Ian Y; Weissman Irving L; Yeung Alan C; Robbins Robert C; Yang Phillip C
In vivo serial evaluation of superparamagnetic iron-oxide labeled stem cells by off-resonance positive contrast.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2008;60(6):1269-75.
2008: Cao Yu-An; Wagers Amy J; Karsunky Holger; Zhao Hui; Reeves Robert; Wong Ronald J; Stevenson David K; Weissman Irving L; Contag Christopher H
Heme oxygenase-1 deficiency leads to disrupted response to acute stress in stem cells and progenitors.
Blood 2008;112(12):4494-502.
2008: Kalani M Yashar S; Cheshier Samuel H; Cord Branden J; Bababeygy Simon R; Vogel Hannes; Weissman Irving L; Palmer Theo D; Nusse Roel
Wnt-mediated self-renewal of neural stem/progenitor cells.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(44):16970-5.
2008: Weissman Irving L; Shizuru Judith A
The origins of the identification and isolation of hematopoietic stem cells, and their capability to induce donor-specific transplantation tolerance and treat autoimmune diseases.
Blood 2008;112(9):3543-53.
2008: Hendry Stephen L; van der Bogt Koen E A; Sheikh Ahmad Y; Arai Takayasu; Dylla Scott J; Drukker Micha; McConnell Michael V; Kutschka Ingo; Hoyt Grant; Cao Feng; Weissman Irving L; Connolly Andrew J; Pelletier Marc P; Wu Joseph C; Robbins Robert C; Yang Phillip C
Multimodal evaluation of in vivo magnetic resonance imaging of myocardial restoration by mouse embryonic stem cells.
The Journal of thoracic and cardiovascular surgery 2008;136(4):1028-1037.e1.
2008: Voskoboynik Ayelet; Soen Yoav; Rinkevich Yuval; Rosner Amalia; Ueno Hiroo; Reshef Ram; Ishizuka Katherine J; Palmeri Karla J; Moiseeva Elizabeth; Rinkevich Baruch; Weissman Irving L
Identification of the endostyle as a stem cell niche in a colonial chordate.
Cell stem cell 2008;3(4):456-64.
2008: Viatour Patrick; Somervaille Tim C; Venkatasubrahmanyam Shivkumar; Kogan Scott; McLaughlin Margaret E; Weissman Irving L; Butte Atul J; Passegué Emmanuelle; Sage Julien
Hematopoietic stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family.
Cell stem cell 2008;3(4):416-28.
2008: Gazit Roi; Weissman Irving L; Rossi Derrick J
Hematopoietic stem cells and the aging hematopoietic system.
Seminars in hematology 2008;45(4):218-24.
2008: Bhattacharya Deepta; Ehrlich Lauren I Richie; Weissman Irving L
Space-time considerations for hematopoietic stem cell transplantation.
European journal of immunology 2008;38(8):2060-7.
2008: Weissman Irving L
The E. Donnall Thomas lecture: normal and neoplastic stem cells.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2008;14(8):849-58.
2008: Xiong Anming; Austin Timothy W; Lagasse Eric; Uchida Nobuko; Tamaki Stanley; Bordier Bruno B; Weissman Irving L; Glenn Jeffrey S; Millan Maria T
Isolation of human fetal liver progenitors and their enhanced proliferation by three-dimensional coculture with endothelial cells.
Tissue engineering. Part A 2008;14(6):995-1006.
2008: Karsunky Holger; Inlay Matthew A; Serwold Thomas; Bhattacharya Deepta; Weissman Irving L
Flk2+ common lymphoid progenitors possess equivalent differentiation potential for the B and T lineages.
Blood 2008;111(12):5562-70.
2008: Purhonen Susanna; Palm Jarmo; Rossi Derrick; Kaskenpää Nina; Rajantie Iiro; Ylä-Herttuala Seppo; Alitalo Kari; Weissman Irving L; Salven Petri
Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growth.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(18):6620-5.
2008: Rossi Derrick J; Jamieson Catriona H M; Weissman Irving L
Stems cells and the pathways to aging and cancer.
Cell 2008;132(4):681-96.
2008: Bababeygy Simon R; Cheshier Samuel H; Hou Lewis C; Higgins Dominique M O; Weissman Irving L; Tse Victor C K
Hematopoietic stem cell-derived pericytic cells in brain tumor angio-architecture.
Stem cells and development 2008;17(1):11-8.
2008: Beliakoff Jason; Lee Jane; Ueno Hiroo; Aiyer Aparna; Weissman Irving L; Barsh Gregory S; Cardiff Robert D; Sun Zijie
The PIAS-like protein Zimp10 is essential for embryonic viability and proper vascular development.
Molecular and cellular biology 2008;28(1):282-92.
2008: Chao M P; Seita J; Weissman I L
Establishment of a normal hematopoietic and leukemia stem cell hierarchy.
Cold Spring Harbor symposia on quantitative biology 2008;73():439-49.
2008: Cao Feng; Wagner Roger A; Wilson Kitchener D; Xie Xiaoyan; Fu Ji-Dong; Drukker Micha; Lee Andrew; Li Ronald A; Gambhir Sanjiv S; Weissman Irving L; Robbins Robert C; Wu Joseph C
Transcriptional and functional profiling of human embryonic stem cell-derived cardiomyocytes.
PloS one 2008;3(10):e3474.
2007: Majeti Ravindra; Park Christopher Y; Weissman Irving L
Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood.
Cell stem cell 2007;1(6):635-45.
2007: Warren Luigi A; Rossi Derrick J; Schiebinger Geoffrey R; Weissman Irving L; Kim Stuart K; Quake Stephen R
Transcriptional instability is not a universal attribute of aging.
Aging cell 2007;6(6):775-82.
2007: Czechowicz Agnieszka; Kraft Daniel; Weissman Irving L; Bhattacharya Deepta
Efficient transplantation via antibody-based clearance of hematopoietic stem cell niches.
Science (New York, N.Y.) 2007;318(5854):1296-9.
2007: Bhattacharya Deepta; Cheah Ming T; Franco Christopher B; Hosen Naoki; Pin Christopher L; Sha William C; Weissman Irving L
Transcriptional profiling of antigen-dependent murine B cell differentiation and memory formation.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(10):6808-19.
2007: Pronk Cornelis J H; Rossi Derrick J; Månsson Robert; Attema Joanne L; Norddahl Gudmundur Logi; Chan Charles Kwok Fai; Sigvardsson Mikael; Weissman Irving L; Bryder David
Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy.
Cell stem cell 2007;1(4):428-42.
2007: Ailles Laurie E; Weissman Irving L
Cancer stem cells in solid tumors.
Current opinion in biotechnology 2007;18(5):460-6.
2007: Cheshier Samuel H; Prohaska Susan S; Weissman Irving L
The effect of bleeding on hematopoietic stem cell cycling and self-renewal.
Stem cells and development 2007;16(5):707-17.
2007: Rossi Derrick J; Seita Jun; Czechowicz Agnieszka; Bhattacharya Deepta; Bryder David; Weissman Irving L
Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during aging.
Cell cycle (Georgetown, Tex.) 2007;6(19):2371-6.
2007: Hosen N; Shirakata T; Nishida S; Yanagihara M; Tsuboi A; Kawakami M; Oji Y; Oka Y; Okabe M; Tan B; Sugiyama H; Weissman I L
The Wilms' tumor gene WT1-GFP knock-in mouse reveals the dynamic regulation of WT1 expression in normal and leukemic hematopoiesis.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(8):1783-91.
2007: Attema Joanne L; Papathanasiou Peter; Forsberg E Camilla; Xu Jian; Smale Stephen T; Weissman Irving L
Epigenetic characterization of hematopoietic stem cell differentiation using miniChIP and bisulfite sequencing analysis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(30):12371-6.
2007: Xu Jian; Pope Scott D; Jazirehi Ali R; Attema Joanne L; Papathanasiou Peter; Watts Jason A; Zaret Kenneth S; Weissman Irving L; Smale Stephen T
Pioneer factor interactions and unmethylated CpG dinucleotides mark silent tissue-specific enhancers in embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(30):12377-82.
2007: Serwold Thomas; Hochedlinger Konrad; Inlay Matthew A; Jaenisch Rudolf; Weissman Irving L
Early TCR expression and aberrant T cell development in mice with endogenous prerearranged T cell receptor genes.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(2):928-38.
2007: Hosen Naoki; Yamane Toshiyuki; Muijtjens Manja; Pham Kara; Clarke Michael F; Weissman Irving L
Bmi-1-green fluorescent protein-knock-in mice reveal the dynamic regulation of bmi-1 expression in normal and leukemic hematopoietic cells.
Stem cells (Dayton, Ohio) 2007;25(7):1635-44.
2007: Hosen Naoki; Park Christopher Y; Tatsumi Naoya; Oji Yusuke; Sugiyama Haruo; Gramatzki Martin; Krensky Alan M; Weissman Irving L
CD96 is a leukemic stem cell-specific marker in human acute myeloid leukemia.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(26):11008-13.
2007: Rossi Derrick J; Bryder David; Seita Jun; Nussenzweig Andre; Hoeijmakers Jan; Weissman Irving L
Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age.
Nature 2007;447(7145):725-9.
2007: Voskoboynik Ayelet; Simon-Blecher Noa; Soen Yoav; Rinkevich Baruch; De Tomaso Anthony W; Ishizuka Katherine J; Weissman Irving L
Striving for normality: whole body regeneration through a series of abnormal generations.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(7):1335-44.
2007: Rossi Derrick J; Bryder David; Weissman Irving L
Hematopoietic stem cell aging: mechanism and consequence.
Experimental gerontology 2007;42(5):385-90.
2007: Sanyal Mrinmoy; Tung James W; Karsunky Holger; Zeng Hong; Selleri Licia; Weissman Irving L; Herzenberg Leonore A; Cleary Michael L
B-cell development fails in the absence of the Pbx1 proto-oncogene.
Blood 2007;109(10):4191-9.
2007: Serafini Marta; Dylla Scott J; Oki Masayuki; Heremans Yves; Tolar Jakub; Jiang Yuehua; Buckley Shannon M; Pelacho Beatriz; Burns Terry C; Frommer Sarah; Rossi Derrick J; Bryder David; Panoskaltsis-Mortari Angela; O'Shaughnessy Matthew J; Nelson-Holte Molly; Fine Gabriel C; Weissman Irving L; Blazar Bruce R; Verfaillie Catherine M
Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells.
The Journal of experimental medicine 2007;204(1):129-39.
2007: Prince M E; Sivanandan R; Kaczorowski A; Wolf G T; Kaplan M J; Dalerba P; Weissman I L; Clarke M F; Ailles L E
Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(3):973-8.
2007: Drukker Micha; Muscat Christina; Weissman Irving L
Generation of a monoclonal antibody library against human embryonic stem cells.
Methods in molecular biology (Clifton, N.J.) 2007;407():63-81.
2007: Cao Feng; Drukker Micha; Lin Shuan; Sheikh Ahmad Y; Xie Xiaoyan; Li Zongjin; Connolly Andrew J; Weissman Irving L; Wu Joseph C
Molecular imaging of embryonic stem cell misbehavior and suicide gene ablation.
Cloning and stem cells 2007;9(1):107-17.
2006: Tan Brenton Thomas; Park Christopher Yongchul; Ailles Laurie Elizabeth; Weissman Irving L
The cancer stem cell hypothesis: a work in progress.
Laboratory investigation; a journal of technical methods and pathology 2006;86(12):1203-7.
2006: Warren Luigi; Bryder David; Weissman Irving L; Quake Stephen R
Transcription factor profiling in individual hematopoietic progenitors by digital RT-PCR.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(47):17807-12.
2006: Ueno Hiroo; Weissman Irving L
Clonal analysis of mouse development reveals a polyclonal origin for yolk sac blood islands.
Developmental cell 2006;11(4):519-33.
2006: Clarke Michael F; Dick John E; Dirks Peter B; Eaves Connie J; Jamieson Catriona H M; Jones D Leanne; Visvader Jane; Weissman Irving L; Wahl Geoffrey M
Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells.
Cancer research 2006;66(19):9339-44.
2006: Santarelli Justin G; Udani Vikram; Yung Yun C; Cheshier Sam; Wagers Amy; Brekken Rolf A; Weissman Irving; Tse Victor
Incorporation of bone marrow-derived Flk-1-expressing CD34+ cells in the endothelium of tumor vessels in the mouse brain.
Neurosurgery 2006;59(2):374-82; discussion 374-82.
2006: Bryder David; Rossi Derrick J; Weissman Irving L
Hematopoietic stem cells: the paradigmatic tissue-specific stem cell.
The American journal of pathology 2006;169(2):338-46.
2006: Forsberg E Camilla; Serwold Thomas; Kogan Scott; Weissman Irving L; Passegué Emmanuelle
New evidence supporting megakaryocyte-erythrocyte potential of flk2/flt3+ multipotent hematopoietic progenitors.
Cell 2006;126(2):415-26.
2006: Nyholm Spencer V; Passegue Emmanuelle; Ludington William B; Voskoboynik Ayelet; Mitchel Katrina; Weissman Irving L; De Tomaso Anthony W
fester, A candidate allorecognition receptor from a primitive chordate.
Immunity 2006;25(1):163-73.
2006: Bhattacharya Deepta; Bryder David; Rossi Derrick J; Weissman Irving L
Rapid lymphocyte reconstitution of unconditioned immunodeficient mice with non-self-renewing multipotent hematopoietic progenitors.
Cell cycle (Georgetown, Tex.) 2006;5(11):1135-9.
2006: Rossi Derrick J; Weissman Irving L
Pten, tumorigenesis, and stem cell self-renewal.
Cell 2006;125(2):229-31.
2006: Jamieson Catriona H M; Gotlib Jason; Durocher Jeffrey A; Chao Mark P; Mariappan M Rajan; Lay Marla; Jones Carol; Zehnder James L; Lilleberg Stan L; Weissman Irving L
The JAK2 V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid differentiation.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(16):6224-9.
2006: Wagers Amy J; Weissman Irving L
Differential expression of alpha2 integrin separates long-term and short-term reconstituting Lin-/loThy1.1(lo)c-kit+ Sca-1+ hematopoietic stem cells.
Stem cells (Dayton, Ohio) 2006;24(4):1087-94.
2006: Cao Feng; Lin Shuan; Xie Xiaoyan; Ray Pritha; Patel Manishkumar; Zhang Xianzhong; Drukker Micha; Dylla Scott J; Connolly Andrew J; Chen Xiaoyuan; Weissman Irving L; Gambhir Sanjiv S; Wu Joseph C
In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery.
Circulation 2006;113(7):1005-14.
2006: Mende Ines; Karsunky Holger; Weissman Irving L; Engleman Edgar G; Merad Miriam
Flk2+ myeloid progenitors are the main source of Langerhans cells.
Blood 2006;107(4):1383-90.
2006: Hsu Chia-Lin; King-Fleischman Angela G; Lai Anne Y; Matsumoto Yukie; Weissman Irving L; Kondo Motonari
Antagonistic effect of CCAAT enhancer-binding protein-alpha and Pax5 in myeloid or lymphoid lineage choice in common lymphoid progenitors.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(3):672-7.
2006: Bhattacharya Deepta; Rossi Derrick J; Bryder David; Weissman Irving L
Purified hematopoietic stem cell engraftment of rare niches corrects severe lymphoid deficiencies without host conditioning.
The Journal of experimental medicine 2006;203(1):73-85.
2006: Forsberg E Camilla; Bhattacharya Deepta; Weissman Irving L
Hematopoietic stem cells: expression profiling and beyond.
Stem cell reviews 2006;2(1):23-30.
2005: Laird Diana J; De Tomaso Anthony W; Weissman Irving L
Stem cells are units of natural selection in a colonial ascidian.
Cell 2005;123(7):1351-60.
2005: Passegué Emmanuelle; Wagers Amy J; Giuriato Sylvie; Anderson Wade C; Weissman Irving L
Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates.
The Journal of experimental medicine 2005;202(11):1599-611.
2005: De Tomaso Anthony W; Nyholm Spencer V; Palmeri Karla J; Ishizuka Katherine J; Ludington William B; Mitchel Katrina; Weissman Irving L
Isolation and characterization of a protochordate histocompatibility locus.
Nature 2005;438(7067):454-9.
2005: Huhn Stephen L; Yung Yun; Cheshier Samuel; Harsh Griffith; Ailles Laurie; Weissman Irving; Vogel Hannes; Tse Victor
Identification of phenotypic neural stem cells in a pediatric astroblastoma.
Journal of neurosurgery 2005;103(5 Suppl):446-50.
2005: Udani V M; Santarelli J G; Yung Y C; Wagers A J; Cheshier S H; Weissman I L; Tse V
Hematopoietic stem cells give rise to perivascular endothelial-like cells during brain tumor angiogenesis.
Stem cells and development 2005;14(5):478-86.
2005: García-Ojeda Marcos E; Dejbakhsh-Jones Sussan; Chatterjea-Matthes Devavani; Mukhopadhyay Aditi; BitMansour Andrew; Weissman Irving L; Brown Janice M Y; Strober Samuel
Stepwise development of committed progenitors in the bone marrow that generate functional T cells in the absence of the thymus.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(7):4363-73.
2005: Weissman Irving
Stem cell research: paths to cancer therapies and regenerative medicine.
JAMA : the journal of the American Medical Association 2005;294(11):1359-66.
2005: Forsberg E Camilla; Prohaska Susan S; Katzman Sol; Heffner Garrett C; Stuart Josh M; Weissman Irving L
Differential expression of novel potential regulators in hematopoietic stem cells.
PLoS genetics 2005;1(3):e28.
2005: Kofidis Theo; deBruin Jorg Lucas; Tanaka Masashi; Zwierzchoniewska Monika; Weissman Irving; Fedoseyeva Eugenia; Haverich Axel; Robbins Robert Clayton
They are not stealthy in the heart: embryonic stem cells trigger cell infiltration, humoral and T-lymphocyte-based host immune response.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2005;28(3):461-6.
2005: Chen Ching-Cheng; Grimbaldeston Michele A; Tsai Mindy; Weissman Irving L; Galli Stephen J
Identification of mast cell progenitors in adult mice.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(32):11408-13.
2005: Rossi Derrick J; Bryder David; Zahn Jacob M; Ahlenius Henrik; Sonu Rebecca; Wagers Amy J; Weissman Irving L
Cell intrinsic alterations underlie hematopoietic stem cell aging.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(26):9194-9.
2005: Massengale Mei; Wagers Amy J; Vogel Hannes; Weissman Irving L
Hematopoietic cells maintain hematopoietic fates upon entering the brain.
The Journal of experimental medicine 2005;201(10):1579-89.
2005: Kofidis Theo; de Bruin Jorg L; Yamane Toshiyuki; Tanaka Masashi; Lebl Darren R; Swijnenburg Rutger-Jan; Weissman Irving L; Robbins Robert C
Stimulation of paracrine pathways with growth factors enhances embryonic stem cell engraftment and host-specific differentiation in the heart after ischemic myocardial injury.
Circulation 2005;111(19):2486-93.
2005: Yamane Toshiyuki; Dylla Scott J; Muijtjens Manja; Weissman Irving L
Enforced Bcl-2 expression overrides serum and feeder cell requirements for mouse embryonic stem cell self-renewal.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(9):3312-7.
2005: Ranheim Erik A; Kwan Helen C K; Reya Tannishtha; Wang Yu-Ker; Weissman Irving L; Francke Uta
Frizzled 9 knock-out mice have abnormal B-cell development.
Blood 2005;105(6):2487-94.
2005: Conboy Irina M; Conboy Michael J; Wagers Amy J; Girma Eric R; Weissman Irving L; Rando Thomas A
Rejuvenation of aged progenitor cells by exposure to a young systemic environment.
Nature 2005;433(7027):760-4.
2005: Karsunky Holger; Merad Miriam; Mende Ines; Manz Markus G; Engleman Edgar G; Weissman Irving L
Developmental origin of interferon-alpha-producing dendritic cells from hematopoietic precursors.
Experimental hematology 2005;33(2):173-81.
2005: Santarelli J G; Udani V; Yung C Y; Cheshier S; Wagers A; Brekken R A; Weissman I; Tse V
Preuss Resident Research Award: bone marrow-derived Flk-1-expressing CD34+ cells contribute to the endothelium of tumor vessels in mouse brain.
Clinical neurosurgery 2005;52():384-8.
2005: Weissman Irving L
Normal and neoplastic stem cells.
Novartis Foundation symposium 2005;265():35-50; discussion 50-4, 92-7.
2004: Ranheim Erik A; Tarbell Kristin V; Krogsgaard Michelle; Mallet-Designe Valérie; Teyton Luc; McDevitt Hugh O; Weissman Irving L
Selection of aberrant class II restricted CD8+ T cells in NOD mice expressing a glutamic acid decarboxylase (GAD)65-specific T cell receptor transgene.
Autoimmunity 2004;37(8):555-67.
2004: Yung Yun C; Cheshier Samuel; Santarelli Justin G; Huang Zan; Wagers Amy; Weissman Irving; Tse Victor
Incorporation of naive bone marrow derived cells into the vascular architecture of brain tumor.
Microcirculation (New York, N.Y. : 1994) 2004;11(8):699-708.
2004: Jamieson Catriona H M; Weissman Irving L; Passegué Emmanuelle
Chronic versus acute myelogenous leukemia: a question of self-renewal.
Cancer cell 2004;6(6):531-3.
2004: Sherwood Richard I; Christensen Julie L; Conboy Irina M; Conboy Michael J; Rando Thomas A; Weissman Irving L; Wagers Amy J
Isolation of adult mouse myogenic progenitors: functional heterogeneity of cells within and engrafting skeletal muscle.
Cell 2004;119(4):543-54.
2004: Passegué Emmanuelle; Wagner Erwin F; Weissman Irving L
JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells.
Cell 2004;119(3):431-43.
2004: Jamieson Catriona H M; Ailles Laurie E; Dylla Scott J; Muijtjens Manja; Jones Carol; Zehnder James L; Gotlib Jason; Li Kevin; Manz Markus G; Keating Armand; Sawyers Charles L; Weissman Irving L
Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML.
The New England journal of medicine 2004;351(7):657-67.
2004: Kelly S; Bliss T M; Shah A K; Sun G H; Ma M; Foo W C; Masel J; Yenari M A; Weissman I L; Uchida N; Palmer T; Steinberg G K
Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat cerebral cortex.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(32):11839-44.
2004: Baiker Armin; Fabel Klaus; Cozzio Antonio; Zerboni Leigh; Fabel Konstanze; Sommer Marvin; Uchida Nobuko; He Dongping; Weissman Irving; Arvin Ann M
Varicella-zoster virus infection of human neural cells in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(29):10792-7.
2004: Merad Miriam; Hoffmann Petra; Ranheim Erik; Slaymaker Sarah; Manz Markus G; Lira Sergio A; Charo Israel; Cook Donald N; Weissman Irving L; Strober Samuel; Engleman Edgar G
Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease.
Nature medicine 2004;10(5):510-7.
2004: So Chi Wai; Karsunky Holger; Wong Piu; Weissman Irving L; Cleary Michael L
Leukemic transformation of hematopoietic progenitors by MLL-GAS7 in the absence of Hoxa7 or Hoxa9.
Blood 2004;103(8):3192-9.
2004: Balsam Leora B; Wagers Amy J; Christensen Julie L; Kofidis Theo; Weissman Irving L; Robbins Robert C
Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium.
Nature 2004;428(6983):668-73.
2004: Christensen Julie L; Wright Douglas E; Wagers Amy J; Weissman Irving L
Circulation and chemotaxis of fetal hematopoietic stem cells.
PLoS biology 2004;2(3):E75.
2004: Wagers Amy J; Weissman Irving L
Plasticity of adult stem cells.
Cell 2004;116(5):639-48.
2004: Al-Hajj Muhammad; Becker Michael W; Wicha Max; Weissman Irving; Clarke Michael F
Therapeutic implications of cancer stem cells.
Current opinion in genetics & development 2004;14(1):43-7.
2004: De Tomaso Anthony W; Weissman Irving L
Evolution of a protochordate allorecognition locus.
Science (New York, N.Y.) 2004;303(5660):977.
2004: Cao Yu-An; Wagers Amy J; Beilhack Andreas; Dusich Joan; Bachmann Michael H; Negrin Robert S; Weissman Irving L; Contag Christopher H
Shifting foci of hematopoiesis during reconstitution from single stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(1):221-6.
2004: Sherwood Richard I; Christensen Julie L; Weissman Irving L; Wagers Amy J
Determinants of skeletal muscle contributions from circulating cells, bone marrow cells, and hematopoietic stem cells.
Stem cells (Dayton, Ohio) 2004;22(7):1292-304.
2004: Kofidis Theo; de Bruin Jorg L; Yamane Toshiyuki; Balsam Leora B; Lebl Darren R; Swijnenburg Rutger-Jan; Tanaka Masashi; Weissman Irving L; Robbins Robert C
Insulin-like growth factor promotes engraftment, differentiation, and functional improvement after transfer of embryonic stem cells for myocardial restoration.
Stem cells (Dayton, Ohio) 2004;22(7):1239-45.
2003: Cozzio Antonio; Passegué Emmanuelle; Ayton Paul M; Karsunky Holger; Cleary Michael L; Weissman Irving L
Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors.
Genes & development 2003;17(24):3029-35.
2003: Easterday Mathew C; Dougherty Joseph D; Jackson Robert L; Ou Jing; Nakano Ichiro; Paucar Andres A; Roobini Babak; Dianati Mehrnoosh; Irvin Dwain K; Weissman Irving L; Terskikh Alexey V; Geschwind Daniel H; Kornblum Harley I
Neural progenitor genes. Germinal zone expression and analysis of genetic overlap in stem cell populations.
Developmental biology 2003;264(2):309-22.
2003: De Tomaso Anthony W; Weissman Irving L
Initial characterization of a protochordate histocompatibility locus.
Immunogenetics 2003;55(7):480-90.
2003: Passegué Emmanuelle; Jamieson Catriona H M; Ailles Laurie E; Weissman Irving L
Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?
Proceedings of the National Academy of Sciences of the United States of America 2003;100 Suppl 1():11842-9.
2003: Jaiswal Siddhartha; Traver David; Miyamoto Toshihiro; Akashi Koichi; Lagasse Eric; Weissman Irving L
Expression of BCR/ABL and BCL-2 in myeloid progenitors leads to myeloid leukemias.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(17):10002-7.
2003: Chatterjea-Matthes Devavani; García-Ojeda Marcos E; Dejbakhsh-Jones Sussan; Jerabek Libuse; Manz Markus G; Weissman Irving L; Strober Samuel
Early defect prethymic in bone marrow T cell progenitors in athymic nu/nu mice.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(3):1207-15.
2003: Karsunky Holger; Merad Miriam; Cozzio Antonio; Weissman Irving L; Manz Markus G
Flt3 ligand regulates dendritic cell development from Flt3+ lymphoid and myeloid-committed progenitors to Flt3+ dendritic cells in vivo.
The Journal of experimental medicine 2003;198(2):305-13.
2003: Domen Jos; Weissman Irving L
Hematopoietic stem cells and other hematopoietic cells show broad resistance to chemotherapeutic agents in vivo when overexpressing bcl-2.
Experimental hematology 2003;31(7):631-9.
2003: Allsopp Richard C; Morin Gregg B; DePinho Ronald; Harley Calvin B; Weissman Irving L
Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation.
Blood 2003;102(2):517-20.
2003: Arber Caroline; BitMansour Andrew; Sparer Timothy E; Higgins John P; Mocarski Edward S; Weissman Irving L; Shizuru Judith A; Brown Janice M Y
Common lymphoid progenitors rapidly engraft and protect against lethal murine cytomegalovirus infection after hematopoietic stem cell transplantation.
Blood 2003;102(2):421-8.
2003: Terskikh Alexey V; Miyamoto Toshihiro; Chang Cynthia; Diatchenko Luda; Weissman Irving L
Gene expression analysis of purified hematopoietic stem cells and committed progenitors.
Blood 2003;102(1):94-101.
2003: Willert Karl; Brown Jeffrey D; Danenberg Esther; Duncan Andrew W; Weissman Irving L; Reya Tannishtha; Yates John R; Nusse Roel
Wnt proteins are lipid-modified and can act as stem cell growth factors.
Nature 2003;423(6938):448-52.
2003: Reya Tannishtha; Duncan Andrew W; Ailles Laurie; Domen Jos; Scherer David C; Willert Karl; Hintz Lindsay; Nusse Roel; Weissman Irving L
A role for Wnt signalling in self-renewal of haematopoietic stem cells.
Nature 2003;423(6938):409-14.
2003: Park In-kyung; Qian Dalong; Kiel Mark; Becker Michael W; Pihalja Michael; Weissman Irving L; Morrison Sean J; Clarke Michael F
Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells.
Nature 2003;423(6937):302-5.
2003: Allsopp Richard C; Morin Gregg B; Horner James W; DePinho Ronald; Harley Calvin B; Weissman Irving L
Effect of TERT over-expression on the long-term transplantation capacity of hematopoietic stem cells.
Nature medicine 2003;9(4):369-71.
2003: de Tomaso Anthony W; Weissman Irving L
Construction and characterization of large-insert genomic libraries (BAC and fosmid) from the Ascidian Botryllus schlosseri and initial physical mapping of a histocompatibility locus.
Marine biotechnology (New York, N.Y.) 2003;5(2):103-15.
2003: So Chi Wai; Karsunky Holger; Passegué Emmanuelle; Cozzio Antonio; Weissman Irving L; Cleary Michael L
MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in mice.
Cancer cell 2003;3(2):161-71.
2003: Beilhack Georg F; Scheffold Yolanda C; Weissman Irving L; Taylor Cariel; Jerabek Libuse; Burge Matthew J; Masek Marilyn A; Shizuru Judith A
Purified allogeneic hematopoietic stem cell transplantation blocks diabetes pathogenesis in NOD mice.
Diabetes 2003;52(1):59-68.
2003: Nakorn Thanyaphong Na; Miyamoto Toshihiro; Weissman Irving L
Characterization of mouse clonogenic megakaryocyte progenitors.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(1):205-10.
2003: Kondo Motonari; Wagers Amy J; Manz Markus G; Prohaska Susan S; Scherer David C; Beilhack Georg F; Shizuru Judith A; Weissman Irving L
Biology of hematopoietic stem cells and progenitors: implications for clinical application.
Annual review of immunology 2003;21():759-806.
2002: Allsopp Richard C; Cheshier Samuel; Weissman Irving L
Telomerase activation and rejuvenation of telomere length in stimulated T cells derived from serially transplanted hematopoietic stem cells.
The Journal of experimental medicine 2002;196(11):1427-33.
2002: Prohaska Susan S; Scherer David C; Weissman Irving L; Kondo Motonari
Developmental plasticity of lymphoid progenitors.
Seminars in immunology 2002;14(6):377-84.
2002: Merad Miriam; Manz Markus G; Karsunky Holger; Wagers Amy; Peters Wendy; Charo Israel; Weissman Irving L; Cyster Jason G; Engleman Edgar G
Langerhans cells renew in the skin throughout life under steady-state conditions.
Nature immunology 2002;3(12):1135-41.
2002: BitMansour Andrew; Burns Stacy M; Traver David; Akashi Koichi; Contag Christopher H; Weissman Irving L; Brown Janice M Y
Myeloid progenitors protect against invasive aspergillosis and Pseudomonas aeruginosa infection following hematopoietic stem cell transplantation.
Blood 2002;100(13):4660-7.
2002: Wagers Amy J; Sherwood Richard I; Christensen Julie L; Weissman Irving L
Little evidence for developmental plasticity of adult hematopoietic stem cells.
Science (New York, N.Y.) 2002;297(5590):2256-9.
2002: Manz Markus G; Miyamoto Toshihiro; Akashi Koichi; Weissman Irving L
Prospective isolation of human clonogenic common myeloid progenitors.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(18):11872-7.
2002: Weissman Irving L
The road ended up at stem cells.
Immunological reviews 2002;185():159-74.
2002: Miyamoto Toshihiro; Iwasaki Hiromi; Reizis Boris; Ye Min; Graf Thomas; Weissman Irving L; Akashi Koichi
Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment.
Developmental cell 2002;3(1):137-47.
2002: Na Nakorn Thanyaphong; Traver David; Weissman Irving L; Akashi Koichi
Myeloerythroid-restricted progenitors are sufficient to confer radioprotection and provide the majority of day 8 CFU-S.
The Journal of clinical investigation 2002;109(12):1579-85.
2002: Allsopp Richard C; Weissman Irving L
Replicative senescence of hematopoietic stem cells during serial transplantation: does telomere shortening play a role?
Oncogene 2002;21(21):3270-3.
2002: Wagers A J; Christensen J L; Weissman I L
Cell fate determination from stem cells.
Gene therapy 2002;9(10):606-12.
2002: Weissman Irving L
Stem cells--scientific, medical, and political issues.
The New England journal of medicine 2002;346(20):1576-9.
2002: Wright Douglas E; Bowman Edward P; Wagers Amy J; Butcher Eugene C; Weissman Irving L
Hematopoietic stem cells are uniquely selective in their migratory response to chemokines.
The Journal of experimental medicine 2002;195(9):1145-54.
2002: King Angela G; Kondo Motonari; Scherer David C; Weissman Irving L
Lineage infidelity in myeloid cells with TCR gene rearrangement: a latent developmental potential of proT cells revealed by ectopic cytokine receptor signaling.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(7):4508-13.
2002: Wagers Amy J; Allsopp Richard C; Weissman Irving L
Changes in integrin expression are associated with altered homing properties of Lin(-/lo)Thy1.1(lo)Sca-1(+)c-kit(+) hematopoietic stem cells following mobilization by cyclophosphamide/granulocyte colony-stimulating factor.
Experimental hematology 2002;30(2):176-85.
2002: Park In-Kyung; He Yaqin; Lin Fangming; Laerum Ole D; Tian Qiang; Bumgarner Roger; Klug Christopher A; Li Kaijun; Kuhr Christian; Doyle Michelle J; Xie Tao; Schummer Michèl; Sun Yu; Goldsmith Adam; Clarke Michael F; Weissman Irving L; Hood Leroy; Li Linheng
Differential gene expression profiling of adult murine hematopoietic stem cells.
Blood 2002;99(2):488-98.
2002: Morrison Sean J; Qian Dalong; Jerabek Libuse; Thiel Bonnie A; Park In-Kyung; Ford Preston S; Kiel Mark J; Schork Nicholas J; Weissman Irving L; Clarke Michael F
A genetic determinant that specifically regulates the frequency of hematopoietic stem cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(2):635-42.
2001: Christensen J L; Weissman I L
Flk-2 is a marker in hematopoietic stem cell differentiation: a simple method to isolate long-term stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(25):14541-6.
2001: Wright D E; Wagers A J; Gulati A P; Johnson F L; Weissman I L
Physiological migration of hematopoietic stem and progenitor cells.
Science (New York, N.Y.) 2001;294(5548):1933-6.
2001: Reya T; Morrison S J; Clarke M F; Weissman I L
Stem cells, cancer, and cancer stem cells.
Nature 2001;414(6859):105-11.
2001: Kondo M; Scherer D C; King A G; Manz M G; Weissman I L
Lymphocyte development from hematopoietic stem cells.
Current opinion in genetics & development 2001;11(5):520-6.
2001: Traver D; Miyamoto T; Christensen J; Iwasaki-Arai J; Akashi K; Weissman I L
Fetal liver myelopoiesis occurs through distinct, prospectively isolatable progenitor subsets.
Blood 2001;98(3):627-35.
2001: DiMartino J F; Selleri L; Traver D; Firpo M T; Rhee J; Warnke R; O'Gorman S; Weissman I L; Cleary M L
The Hox cofactor and proto-oncogene Pbx1 is required for maintenance of definitive hematopoiesis in the fetal liver.
Blood 2001;98(3):618-26.
2001: Terskikh A V; Easterday M C; Li L; Hood L; Kornblum H I; Geschwind D H; Weissman I L
From hematopoiesis to neuropoiesis: evidence of overlapping genetic programs.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(14):7934-9.
2001: Manz M G; Traver D; Akashi K; Merad M; Miyamoto T; Engleman E G; Weissman I L
Dendritic cell development from common myeloid progenitors.
Annals of the New York Academy of Sciences 2001;938():167-73; discussion 173-4.
2001: Manz M G; Traver D; Miyamoto T; Weissman I L; Akashi K
Dendritic cell potentials of early lymphoid and myeloid progenitors.
Blood 2001;97(11):3333-41.
2001: Mebius R E; Miyamoto T; Christensen J; Domen J; Cupedo T; Weissman I L; Akashi K
The fetal liver counterpart of adult common lymphoid progenitors gives rise to all lymphoid lineages, CD45+CD4+CD3- cells, as well as macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(11):6593-601.
2001: Allsopp R C; Cheshier S; Weissman I L
Telomere shortening accompanies increased cell cycle activity during serial transplantation of hematopoietic stem cells.
The Journal of experimental medicine 2001;193(8):917-24.
2001: Wright D E; Cheshier S H; Wagers A J; Randall T D; Christensen J L; Weissman I L
Cyclophosphamide/granulocyte colony-stimulating factor causes selective mobilization of bone marrow hematopoietic stem cells into the blood after M phase of the cell cycle.
Blood 2001;97(8):2278-85.
2001: Anderson D J; Gage F H; Weissman I L
Can stem cells cross lineage boundaries?
Nature medicine 2001;7(4):393-5.
2001: Qian F; Hanahan D; Weissman I L
L-selectin can facilitate metastasis to lymph nodes in a transgenic mouse model of carcinogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(7):3976-81.
2001: Geschwind D H; Ou J; Easterday M C; Dougherty J D; Jackson R L; Chen Z; Antoine H; Terskikh A; Weissman I L; Nelson S F; Kornblum H I
A genetic analysis of neural progenitor differentiation.
Neuron 2001;29(2):325-39.
2000: Domen J; Weissman I L
Hematopoietic stem cells need two signals to prevent apoptosis; BCL-2 can provide one of these, Kitl/c-Kit signaling the other.
The Journal of experimental medicine 2000;192(12):1707-18.
2000: Traver D; Akashi K; Manz M; Merad M; Miyamoto T; Engleman E G; Weissman I L
Development of CD8alpha-positive dendritic cells from a common myeloid progenitor.
Science (New York, N.Y.) 2000;290(5499):2152-4.
2000: Terskikh A; Fradkov A; Ermakova G; Zaraisky A; Tan P; Kajava A V; Zhao X; Lukyanov S; Matz M; Kim S; Weissman I; Siebert P
"Fluorescent timer": protein that changes color with time.
Science (New York, N.Y.) 2000;290(5496):1585-8.
2000: Kondo M; Scherer D C; Miyamoto T; King A G; Akashi K; Sugamura K; Weissman I L
Cell-fate conversion of lymphoid-committed progenitors by instructive actions of cytokines.
Nature 2000;407(6802):383-6.
2000: Shizuru J A; Weissman I L; Kernoff R; Masek M; Scheffold Y C
Purified hematopoietic stem cell grafts induce tolerance to alloantigens and can mediate positive and negative T cell selection.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(17):9555-60.
2000: Klug C A; Cheshier S; Weissman I L
Inactivation of a GFP retrovirus occurs at multiple levels in long-term repopulating stem cells and their differentiated progeny.
Blood 2000;96(3):894-901.
2000: Miyamoto T; Weissman I L; Akashi K
AML1/ETO-expressing nonleukemic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocation.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(13):7521-6.
2000: Laird D J; De Tomaso A W; Cooper M D; Weissman I L
50 million years of chordate evolution: seeking the origins of adaptive immunity.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(13):6924-6.
2000: Akashi K; Richie L I; Miyamoto T; Carr W H; Weissman I L
B lymphopoiesis in the thymus.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(10):5221-6.
2000: Akashi K; Reya T; Dalma-Weiszhausz D; Weissman I L
Lymphoid precursors.
Current opinion in immunology 2000;12(2):144-50.
2000: Akashi K; Traver D; Miyamoto T; Weissman I L
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages.
Nature 2000;404(6774):193-7.
2000: Weissman I L
Translating stem and progenitor cell biology to the clinic: barriers and opportunities.
Science (New York, N.Y.) 2000;287(5457):1442-6.
2000: Weissman I L
Stem cells: units of development, units of regeneration, and units in evolution.
Cell 2000;100(1):157-68.
2000: Domen J; Cheshier S H; Weissman I L
The role of apoptosis in the regulation of hematopoietic stem cells: Overexpression of Bcl-2 increases both their number and repopulation potential.
The Journal of experimental medicine 2000;191(2):253-64.
2000: Kondo M; Weissman I L
Function of cytokines in lymphocyte development.
Current topics in microbiology and immunology 2000;251():59-65.
2000: Negrin R S; Atkinson K; Leemhuis T; Hanania E; Juttner C; Tierney K; Hu W W; Johnston L J; Shizurn J A; Stockerl-Goldstein K E; Blume K G; Weissman I L; Bower S; Baynes R; Dansey R; Karanes C; Peters W; Klein J
Transplantation of highly purified CD34+Thy-1+ hematopoietic stem cells in patients with metastatic breast cancer.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2000;6(3):262-71.
1999: Gandy K L; Domen J; Aguila H; Weissman I L
CD8+TCR+ and CD8+TCR- cells in whole bone marrow facilitate the engraftment of hematopoietic stem cells across allogeneic barriers.
Immunity 1999;11(5):579-90.
1999: Stoner D S; Rinkevich B; Weissman I L
Heritable germ and somatic cell lineage competitions in chimeric colonial protochordates.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(16):9148-53.
1999: Akashi K; Traver D; Kondo M; Weissman I L
Lymphoid development from hematopoietic stem cells.
International journal of hematology 1999;69(4):217-26.
1999: Domen J; Weissman I L
Self-renewal, differentiation or death: regulation and manipulation of hematopoietic stem cell fate.
Molecular medicine today 1999;5(5):201-8.
1999: Cheshier S H; Morrison S J; Liao X; Weissman I L
In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):3120-5.
1999: Trahey M; Weissman I L
Cyclophilin C-associated protein: a normal secreted glycoprotein that down-modulates endotoxin and proinflammatory responses in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):3006-11.
1999: Magor B G; De Tomaso A; Rinkevich B; Weissman I L
Allorecognition in colonial tunicates: protection against predatory cell lineages?
Immunological reviews 1999;167():69-79.
1999: Akashi K; Kondo M; Cheshier S; Shizuru J; Gandy K; Domen J; Mebius R; Traver D; Weissman I L
Lymphoid development from stem cells and the common lymphocyte progenitors.
Cold Spring Harbor symposia on quantitative biology 1999;64():1-12.
1998: Rinkevich B; Weissman I L; De Tomaso A W
Transplantation of Fu/HC-incompatible zooids in Botryllus schlosseri results in chimerism.
The Biological bulletin 1998;195(2):98-106.
1998: Mebius R E; van Tuijl S; Weissman I L; Randall T D
Transfer of primitive stem/progenitor bone marrow cells from LT alpha-/- donors to wild-type hosts: implications for the generation of architectural events in lymphoid B cell domains.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(8):3836-43.
1998: Fagan M B; Weissman I L
Characterization of a polymorphic protein localized to vascular epithelium in Botryllus schlosseri: role in tunic synthesis?
Molecular marine biology and biotechnology 1998;7(3):204-13.
1998: Traver D; Akashi K; Weissman I L; Lagasse E
Mice defective in two apoptosis pathways in the myeloid lineage develop acute myeloblastic leukemia.
Immunity 1998;9(1):47-57.
1998: García-Ojeda M E; Dejbakhsh-Jones S; Weissman I L; Strober S
An alternate pathway for T cell development supported by the bone marrow microenvironment: recapitulation of thymic maturation.
The Journal of experimental medicine 1998;187(11):1813-23.
1998: De Tomaso A W; Saito Y; Ishizuka K J; Palmeri K J; Weissman I L
Mapping the genome of a model protochordate. I. A low resolution genetic map encompassing the fusion/histocompatibility (Fu/HC) locus of Botryllus schlosseri.
Genetics 1998;149(1):277-87.
1998: Fagan M B; Weissman I L
Linkage analysis of HSP70 genes and historecognition locus in botryllus schlosseri.
Immunogenetics 1998;47(6):468-76.
1998: Domen J; Gandy K L; Weissman I L
Systemic overexpression of BCL-2 in the hematopoietic system protects transgenic mice from the consequences of lethal irradiation.
Blood 1998;91(7):2272-82.
1998: Hahm K; Cobb B S; McCarty A S; Brown K E; Klug C A; Lee R; Akashi K; Weissman I L; Fisher A G; Smale S T
Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatin.
Genes & development 1998;12(6):782-96.
1998: Akashi K; Kondo M; Weissman I L
Two distinct pathways of positive selection for thymocytes.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(5):2486-91.
1998: Gandy K L; Weissman I L
Tolerance of allogeneic heart grafts in mice simultaneously reconstituted with purified allogeneic hematopoietic stem cells.
Transplantation 1998;65(3):295-304.
1998: Klug C A; Morrison S J; Masek M; Hahm K; Smale S T; Weissman I L
Hematopoietic stem cells and lymphoid progenitors express different Ikaros isoforms, and Ikaros is localized to heterochromatin in immature lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(2):657-62.
1998: Mebius R E; Schadee-Eestermans I L; Weissman I L
MAdCAM-1 dependent colonization of developing lymph nodes involves a unique subset of CD4+CD3- hematolymphoid cells.
Cell adhesion and communication 1998;6(2-3):97-103.
1998: Randall T D; Weissman I L
Characterization of a population of cells in the bone marrow that phenotypically mimics hematopoietic stem cells: resting stem cells or mystery population?
Stem cells (Dayton, Ohio) 1998;16(1):38-48.
1997: Kondo M; Weissman I L; Akashi K
Identification of clonogenic common lymphoid progenitors in mouse bone marrow.
Cell 1997;91(5):661-72.
1997: Mebius R E; Rennert P; Weissman I L
Developing lymph nodes collect CD4+CD3- LTbeta+ cells that can differentiate to APC, NK cells, and follicular cells but not T or B cells.
Immunity 1997;7(4):493-504.
1997: Stoner D S; Quattro J M; Weissman I L
Highly polymorphic microsatellite loci in the colonial ascidian Botryllus schlosseri.
Molecular marine biology and biotechnology 1997;6(3):163-71.
1997: Kondo M; Akashi K; Domen J; Sugamura K; Weissman I L
Bcl-2 rescues T lymphopoiesis, but not B or NK cell development, in common gamma chain-deficient mice.
Immunity 1997;7(1):155-62.
1997: Aguila H L; Akashi K; Domen J; Gandy K L; Lagasse E; Mebius R E; Morrison S J; Shizuru J; Strober S; Uchida N; Wright D E; Weissman I L
From stem cells to lymphocytes: biology and transplantation.
Immunological reviews 1997;157():13-40.
1997: Akashi K; Kondo M; von Freeden-Jeffry U; Murray R; Weissman I L
Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice.
Cell 1997;89(7):1033-41.
1997: Lagasse E; Weissman I L
Enforced expression of Bcl-2 in monocytes rescues macrophages and partially reverses osteopetrosis in op/op mice.
Cell 1997;89(7):1021-31.
1997: Morrison S J; Wandycz A M; Hemmati H D; Wright D E; Weissman I L
Identification of a lineage of multipotent hematopoietic progenitors.
Development (Cambridge, England) 1997;124(10):1929-39.
1997: Morrison S J; Wright D E; Cheshier S H; Weissman I L
Hematopoietic stem cells: challenges to expectations.
Current opinion in immunology 1997;9(2):216-21.
1997: Morrison S J; Wright D E; Weissman I L
Cyclophosphamide/granulocyte colony-stimulating factor induces hematopoietic stem cells to proliferate prior to mobilization.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(5):1908-13.
1997: Fagan M B; Weissman I L
HSP70 genes and historecognition in Botryllus schlosseri: implications for MHC evolution.
Hereditas 1997;127(1-2):25-35.
1996: Stoner D S; Weissman I L
Somatic and germ cell parasitism in a colonial ascidian: possible role for a highly polymorphic allorecognition system.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(26):15254-9.
1996: Tidmarsh G F; Heimfeld S; Whitlock C A; Weissman I L; Müller-Sieburg C E
Identification of a novel bone marrow-derived B-cell progenitor population that coexpresses B220 and Thy-1 and is highly enriched for Abelson leukemia virus targets.
Molecular and cellular biology 1996;16(10):5946.
1996: Lagasse E; Weissman I L
Flow cytometric identification of murine neutrophils and monocytes.
Journal of immunological methods 1996;197(1-2):139-50.
1996: Mebius R E; Streeter P R; Michie S; Butcher E C; Weissman I L
A developmental switch in lymphocyte homing receptor and endothelial vascular addressin expression regulates lymphocyte homing and permits CD4+ CD3- cells to colonize lymph nodes.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(20):11019-24.
1996: Morrison S J; Prowse K R; Ho P; Weissman I L
Telomerase activity in hematopoietic cells is associated with self-renewal potential.
Immunity 1996;5(3):207-16.
1996: Morrison S J; Wandycz A M; Akashi K; Globerson A; Weissman I L
The aging of hematopoietic stem cells.
Nature medicine 1996;2(9):1011-6.
1996: Akashi K; Weissman I L
The c-kit+ maturation pathway in mouse thymic T cell development: lineages and selection.
Immunity 1996;5(2):147-61.
1996: Uchida N; Jerabek L; Weissman I L
Searching for hematopoietic stem cells. II. The heterogeneity of Thy-1.1(lo)Lin(-/lo)Sca-1+ mouse hematopoietic stem cells separated by counterflow centrifugal elutriation.
Experimental hematology 1996;24(5):649-59.
1996: Weissman I L
From thymic lineages back to hematopoietic stem cells, sometimes using homing receptors.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(6):2019-25.
1996: Shizuru J A; Jerabek L; Edwards C T; Weissman I L
Transplantation of purified hematopoietic stem cells: requirements for overcoming the barriers of allogeneic engraftment.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 1996;2(1):3-14.
1996: Aguila H L; Weissman I L
Hematopoietic stem cells are not direct cytotoxic targets of natural killer cells.
Blood 1996;87(4):1225-31.
1996: Fagan M B; Weissman I L
Sequence and characterization of two HSP70 genes in the colonial protochordate Botryllus schlosseri.
Immunogenetics 1996;44(2):134-42.
1995: Mehta B A; Schmidt-Wolf I G; Weissman I L; Negrin R S
Two pathways of exocytosis of cytoplasmic granule contents and target cell killing by cytokine-induced CD3+ CD56+ killer cells.
Blood 1995;86(9):3493-9.
1995: Dejbakhsh-Jones S; Jerabek L; Weissman I L; Strober S
Extrathymic maturation of alpha beta T cells from hemopoietic stem cells.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(7):3338-44.
1995: Morrison S J; Hemmati H D; Wandycz A M; Weissman I L
The purification and characterization of fetal liver hematopoietic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(22):10302-6.
1995: Aguila H L; Hershberger R J; Weissman I L
Transgenic mice carrying the diphtheria toxin A chain gene under the control of the granzyme A promoter: expected depletion of cytotoxic cells and unexpected depletion of CD8 T cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(22):10192-6.
1995: Morrison S J; Weissman I L
Heterogeneity of hematopoietic stem cells: implications for clinical applications.
Proceedings of the Association of American Physicians 1995;107(2):187-94.
1995: Morrison S J; Uchida N; Weissman I L
The biology of hematopoietic stem cells.
Annual review of cell and developmental biology 1995;11():35-71.
1994: Morrison S J; Weissman I L
The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype.
Immunity 1994;1(8):661-73.
1994: Weissman I L
Stem cells, clonal progenitors, and commitment to the three lymphocyte lineages: T, B, and NK cells.
Immunity 1994;1(7):529-31.
1994: Sen-Majumdar A; Guidos C; Kina T; Lieberman M; Weissman I L
Characterization of preneoplastic thymocytes and of their neoplastic progression in irradiated C57BL/Ka mice.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(4):1581-92.
1994: Friedman J; Weissman I; Friedman J; Alpert S
An analysis of the expression of cyclophilin C reveals tissue restriction and an intriguing pattern in the mouse kidney.
The American journal of pathology 1994;144(6):1247-56.
1994: Uchida N; Aguila H L; Fleming W H; Jerabek L; Weissman I L
Rapid and sustained hematopoietic recovery in lethally irradiated mice transplanted with purified Thy-1.1lo Lin-Sca-1+ hematopoietic stem cells.
Blood 1994;83(12):3758-79.
1994: Morrison S J; Lagasse E; Weissman I L
Demonstration that Thy(lo) subsets of mouse bone marrow that express high levels of lineage markers are not significant hematopoietic progenitors.
Blood 1994;83(12):3480-90.
1994: Crowe D T; Chiu H; Fong S; Weissman I L
Regulation of the avidity of integrin alpha 4 beta 7 by the beta 7 cytoplasmic domain.
The Journal of biological chemistry 1994;269(20):14411-8.
1994: Qian F; Vaux D L; Weissman I L
Expression of the integrin alpha 4 beta 1 on melanoma cells can inhibit the invasive stage of metastasis formation.
Cell 1994;77(3):335-47.
1994: Bartl S; Weissman I L
The isolation of putative major histocompatibility complex gene fragments from dogfish and nurse shark.
Annals of the New York Academy of Sciences 1994;712():346-9.
1994: Péault B; Khazaal I; Weissman I L
In vitro development of B cells and macrophages from early mouse fetal thymocytes.
European journal of immunology 1994;24(3):781-4.
1994: Lagasse E; Weissman I L
bcl-2 inhibits apoptosis of neutrophils but not their engulfment by macrophages.
The Journal of experimental medicine 1994;179(3):1047-52.
1994: Sen-Majumdar A; Weissman I L; Hansteen G; Marian J; Waller E K; Lieberman M
Radiation leukemia virus-induced thymic lymphomas express a restricted repertoire of T-cell receptor V beta gene products.
Journal of virology 1994;68(2):1165-72.
1994: Weissman I L
Developmental switches in the immune system.
Cell 1994;76(2):207-18.
1994: Bartl S; Weissman I L
Isolation and characterization of major histocompatibility complex class IIB genes from the nurse shark.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(1):262-6.
1993: Schmidt-Wolf I G; Lefterova P; Mehta B A; Fernandez L P; Huhn D; Blume K G; Weissman I L; Negrin R S
Phenotypic characterization and identification of effector cells involved in tumor cell recognition of cytokine-induced killer cells.
Experimental hematology 1993;21(13):1673-9.
1993: Vaux D L; Weissman I L
Neither macromolecular synthesis nor myc is required for cell death via the mechanism that can be controlled by Bcl-2.
Molecular and cellular biology 1993;13(11):7000-5.
1993: Weissman I L; Cooper M D
How the immune system develops.
Scientific American 1993;269(3):64-71.
1993: Fleming W H; Alpern E J; Uchida N; Ikuta K; Spangrude G J; Weissman I L
Functional heterogeneity is associated with the cell cycle status of murine hematopoietic stem cells.
The Journal of cell biology 1993;122(4):897-902.
1993: Friedman J; Trahey M; Weissman I
Cloning and characterization of cyclophilin C-associated protein: a candidate natural cellular ligand for cyclophilin C.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(14):6815-9.
1993: Kraft D L; Weissman I L; Waller E K
Differentiation of CD3-4-8- human fetal thymocytes in vivo: characterization of a CD3-4+8- intermediate.
The Journal of experimental medicine 1993;178(1):265-77.
1993: Waller E K; Ziemianska M; Bangs C D; Cleary M; Weissman I; Kamel O W
Characterization of posttransplant lymphomas that express T-cell-associated markers: immunophenotypes, molecular genetics, cytogenetics, and heterotransplantation in severe combined immunodeficient mice.
Blood 1993;82(1):247-61.
1993: Berlin C; Berg E L; Briskin M J; Andrew D P; Kilshaw P J; Holzmann B; Weissman I L; Hamann A; Butcher E C
Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1.
Cell 1993;74(1):185-95.
1993: Su L; Hershberger R J; Weissman I L
LYAR, a novel nucleolar protein with zinc finger DNA-binding motifs, is involved in cell growth regulation.
Genes & development 1993;7(5):735-48.
1993: Uchida N; Fleming W H; Alpern E J; Weissman I L
Heterogeneity of hematopoietic stem cells.
Current opinion in immunology 1993;5(2):177-84.
1993: Fleming W H; Alpern E J; Uchida N; Ikuta K; Weissman I L
Steel factor influences the distribution and activity of murine hematopoietic stem cells in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3760-4.
1993: Chen R H; Ivens K W; Alpert S; Billingham M E; Fathman C G; Flavin T F; Shizuru J A; Starnes V A; Weissman I L; Griffiths G M
The use of granzyme A as a marker of heart transplant rejection in cyclosporine or anti-CD4 monoclonal antibody-treated rats.
Transplantation 1993;55(1):146-53.
1993: Hu M C; Holzmann B; Crowe D T; Neuhaus H; Weissman I L
The Peyer's patch homing receptor.
Current topics in microbiology and immunology 1993;184():125-38.
1992: Vaux D L; Weissman I L; Kim S K
Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2.
Science (New York, N.Y.) 1992;258(5090):1955-7.
1992: Waller E K; Sen-Majumdar A; Kamel O W; Hansteen G A; Schick M R; Weissman I L
Human T-cell development in SCID-hu mice: staphylococcal enterotoxins induce specific clonal deletions, proliferation, and anergy.
Blood 1992;80(12):3144-56.
1992: Hershberger R J; Gershenfeld H K; Weissman I L; Su L
Genomic organization of the mouse granzyme A gene. Two mRNAs encode the same mature granzyme A with different leader peptides.
The Journal of biological chemistry 1992;267(35):25488-93.
1992: Hu M C; Crowe D T; Weissman I L; Holzmann B
Cloning and expression of mouse integrin beta p(beta 7): a functional role in Peyer's patch-specific lymphocyte homing.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(17):8254-8.
1992: Lieberman M; Hansteen G A; Waller E K; Weissman I L; Sen-Majumdar A
Unexpected effects of the severe combined immunodeficiency mutation on murine lymphomagenesis.
The Journal of experimental medicine 1992;176(2):399-405.
1992: Vaux D L; Aguila H L; Weissman I L
Bcl-2 prevents death of factor-deprived cells but fails to prevent apoptosis in targets of cell mediated killing.
International immunology 1992;4(7):821-4.
1992: Ikuta K; Kina T; MacNeil I; Uchida N; Peault B; Chien Y H; Weissman I L
Development of gamma delta T-cell subsets from fetal hematopoietic stem cells.
Annals of the New York Academy of Sciences 1992;651():21-32.
1992: Lagasse E; Weissman I L
Mouse MRP8 and MRP14, two intracellular calcium-binding proteins associated with the development of the myeloid lineage.
Blood 1992;79(8):1907-15.
1992: Ikuta K; Weissman I L
Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(4):1502-6.
1992: Griffiths G M; Alpert S; Lambert E; McGuire J; Weissman I L
Perforin and granzyme A expression identifying cytolytic lymphocytes in rheumatoid arthritis.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(2):549-53.
1992: Uchida N; Weissman I L
Searching for hematopoietic stem cells: evidence that Thy-1.1lo Lin- Sca-1+ cells are the only stem cells in C57BL/Ka-Thy-1.1 bone marrow.
The Journal of experimental medicine 1992;175(1):175-84.
1992: Heimfeld S; Weissman I L
Characterization of several classes of mouse hematopoietic progenitor cells.
Current topics in microbiology and immunology 1992;177():95-105.
1992: Hu M C; Siegelman M H; Holzmann B; Crowe D T; Weissman I L
Lymphocyte homing receptors.
Cold Spring Harbor symposia on quantitative biology 1992;57():291-308.
1991: Neuhaus H; Hu M C; Hemler M E; Takada Y; Holzmann B; Weissman I L
Cloning and expression of cDNAs for the alpha subunit of the murine lymphocyte-Peyer's patch adhesion molecule.
The Journal of cell biology 1991;115(4):1149-58.
1991: Ikuta K; Weissman I L
The junctional modifications of a T cell receptor gamma chain are determined at the level of thymic precursors.
The Journal of experimental medicine 1991;174(5):1279-82.
1991: Waller E K; Kamel O W; Cleary M L; Majumdar A S; Schick M R; Lieberman M; Weissman I L
Growth of primary T-cell non-Hodgkin's lymphomata in SCID-hu mice: requirement for a human lymphoid microenvironment.
Blood 1991;78(10):2650-65.
1991: Spangrude G J; Smith L; Uchida N; Ikuta K; Heimfeld S; Friedman J; Weissman I L
Mouse hematopoietic stem cells.
Blood 1991;78(6):1395-402.
1991: Weissman I; Spangrude G; Heimfeld S; Smith L; Uchida N
Stem cells.
Nature 1991;353(6339):26.
1991: Friedman J; Weissman I
Two cytoplasmic candidates for immunophilin action are revealed by affinity for a new cyclophilin: one in the presence and one in the absence of CsA.
Cell 1991;66(4):799-806.
1991: Schmidt-Wolf I G; Negrin R S; Kiem H P; Blume K G; Weissman I L
Use of a SCID mouse/human lymphoma model to evaluate cytokine-induced killer cells with potent antitumor cell activity.
The Journal of experimental medicine 1991;174(1):139-49.
1991: Smith L G; Weissman I L; Heimfeld S
Clonal analysis of hematopoietic stem-cell differentiation in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(7):2788-92.
1991: Griffiths G M; Namikawa R; Mueller C; Liu C C; Young J D; Billingham M; Weissman I
Granzyme A and perforin as markers for rejection in cardiac transplantation.
European journal of immunology 1991;21(3):687-93.
1991: Kina T; Majumdar A S; Heimfeld S; Kaneshima H; Holzmann B; Katsura Y; Weissman I L
Identification of a 107-kD glycoprotein that mediates adhesion between stromal cells and hematolymphoid cells.
The Journal of experimental medicine 1991;173(2):373-81.
1990: van de Rijn M; Weissman I L; Siegelman M
Biosynthesis pathway of gp90MEL-14, the mouse lymph node-specific homing receptor.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(5):1477-82.
1990: Guidos C J; Danska J S; Fathman C G; Weissman I L
T cell receptor-mediated negative selection of autoreactive T lymphocyte precursors occurs after commitment to the CD4 or CD8 lineages.
The Journal of experimental medicine 1990;172(3):835-45.
1990: Ikuta K; Kina T; MacNeil I; Uchida N; Peault B; Chien Y H; Weissman I L
A developmental switch in thymic lymphocyte maturation potential occurs at the level of hematopoietic stem cells.
Cell 1990;62(5):863-74.
1990: Fariñas M C; Adkins B; Stall A M; Weissman I; Strober S
B cell infiltration of the thymic medulla in New Zealand black, New Zealand white, and (New Zealand black x New Zealand white)F1 mice. Effect of total lymphoid irradiation.
Arthritis and rheumatism 1990;33(5):702-10.
1990: Siegelman M H; Cheng I C; Weissman I L; Wakeland E K
The mouse lymph node homing receptor is identical with the lymphocyte cell surface marker Ly-22: role of the EGF domain in endothelial binding.
Cell 1990;61(4):611-22.
1990: Okada C Y; Holzmann B; Guidos C; Palmer E; Weissman I L
Characterization of a rat monoclonal antibody specific for a determinant encoded by the V beta 7 gene segment. Depletion of V beta 7+ T cells in mice with Mls-1a haplotype.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(9):3473-7.
1990: Weissman I L; Saito Y; Rinkevich B
Allorecognition histocompatibility in a protochordate species: is the relationship to MHC somatic or structural?
Immunological reviews 1990;113():227-41.
1990: Majumdar A S; Guidos C; Kaneshima H; White J H; Marian J; Lieberman M; Weissman I L
An immunodominant murine lymphoma cell surface heterodimer marks thymic progenitor subsets.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(1):111-21.
1990: Danska J S; McIntyre B W; McDevitt H O; Weissman I L
Structural similarity between a primitive chordate membrane heterodimer and lymphocyte antigen receptors.
International immunology 1990;2(9):795-802.
1990: Sherwood P J; Weissman I L
The growth factor IL-7 induces expression of a transformation-associated antigen in normal pre-B cells.
International immunology 1990;2(5):399-406.
1989: Guidos C J; Weissman I L; Adkins B
Intrathymic maturation of murine T lymphocytes from CD8+ precursors.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(19):7542-6.
1989: O'Neill H C; Weissman I L
Measurement of binding specificity between T cell lymphomas and murine leukemia viruses.
Journal of immunological methods 1989;122(1):79-90.
1989: Siegelman M H; Weissman I L
Human homologue of mouse lymph node homing receptor: evolutionary conservation at tandem cell interaction domains.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(14):5562-6.
1989: Guidos C J; Weissman I L; Adkins B
Developmental potential of CD4-8- thymocytes. Peripheral progeny include mature CD4-8- T cells bearing alpha beta T cell receptor.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(11):3773-80.
1989: Weissman I L; Heimfeld S; Spangrude G
Haemopoietic stem cell purification.
Immunology today 1989;10(6):184-5.
1989: Holzmann B; Weissman I L
Peyer's patch-specific lymphocyte homing receptors consist of a VLA-4-like alpha chain associated with either of two integrin beta chains, one of which is novel.
The EMBO journal 1989;8(6):1735-41.
1989: van de Rijn M; Heimfeld S; Spangrude G J; Weissman I L
Mouse hematopoietic stem-cell antigen Sca-1 is a member of the Ly-6 antigen family.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(12):4634-8.
1989: Guidos C; Ransom J; Fischer M; Weissman I; Zlotnik A
Role of interleukin-4 in T-cell ontogeny: changes in cell surface phenotype and lymphokine production of immature thymocytes after culture with interleukin-4 and phorbol ester.
Journal of autoimmunity 1989;2 Suppl():141-53.
1989: Tidmarsh G F; Heimfeld S; Whitlock C A; Weissman I L; Müller-Sieburg C E
Identification of a novel bone marrow-derived B-cell progenitor population that coexpresses B220 and Thy-1 and is highly enriched for Abelson leukemia virus targets.
Molecular and cellular biology 1989;9(6):2665-71.
1989: Manyak C L; Norton G P; Lobe C G; Bleackley R C; Gershenfeld H K; Weissman I L; Kumar V; Sigal N H; Koo G C
IL-2 induces expression of serine protease enzymes and genes in natural killer and nonspecific T killer cells.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(10):3707-13.
1989: Okada C Y; Weissman I L
Relative V beta transcript levels in thymus and peripheral lymphoid tissues from various mouse strains. Inverse correlation of I-E and Mls expression with relative abundance of several V beta transcripts in peripheral lymphoid tissues.
The Journal of experimental medicine 1989;169(5):1703-19.
1989: Holzmann B; Weissman I L
Integrin molecules involved in lymphocyte homing to Peyer's patches.
Immunological reviews 1989;108():45-61.
1989: Siegelman M H; van de Rijn M; Weissman I L
Mouse lymph node homing receptor cDNA clone encodes a glycoprotein revealing tandem interaction domains.
Science (New York, N.Y.) 1989;243(4895):1165-72.
1989: Spangrude G J; Klein J; Heimfeld S; Aihara Y; Weissman I L
Two monoclonal antibodies identify thymic-repopulating cells in mouse bone marrow.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(2):425-30.
1989: Holzmann B; McIntyre B W; Weissman I L
Identification of a murine Peyer's patch--specific lymphocyte homing receptor as an integrin molecule with an alpha chain homologous to human VLA-4 alpha.
Cell 1989;56(1):37-46.
1989: Heimfeld S; Guidos C J; Holzmann B; Siegelman M H; Weissman I L
Developmental analysis of the mouse hematolymphoid system.
Cold Spring Harbor symposia on quantitative biology 1989;54 Pt 1():75-85.
1989: Hershberger R J; Mueller C; Gershenfeld H K; Weissman I L
A serine protease-encoding gene that marks activated cytotoxic T cells in vivo and in vitro.
Current topics in microbiology and immunology 1989;140():81-92.
1989: Müller-Sieburg C E; Tidmarsh G F; Weissman I L; Spangrude G J
Maturation of hematolymphoid cells that express Thy-1.
Immunology series 1989;45():289-316.
1989: Weissman I L
Some observation on the life history of lymphocytes.
Harvey lectures 1989;85():43-69.
1988: Namikawa R; Kaneshima H; Lieberman M; Weissman I L; McCune J M
Infection of the SCID-hu mouse by HIV-1.
Science (New York, N.Y.) 1988;242(4886):1684-6.
1988: Jung T M; Gallatin W M; Weissman I L; Dailey M O
Down-regulation of homing receptors after T cell activation.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(12):4110-7.
1988: Spangrude G J; Aihara Y; Weissman I L; Klein J
The stem cell antigens Sca-1 and Sca-2 subdivide thymic and peripheral T lymphocytes into unique subsets.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(11):3697-707.
1988: Wood G S; Mueller C; Warnke R A; Weissman I L
In situ localization of HuHF serine protease mRNA and cytotoxic cell-associated antigens in human dermatoses. A novel method for the detection of cytotoxic cells in human tissues.
The American journal of pathology 1988;133(2):218-25.
1988: Spangrude G J; Weissman I L
Mature T cells generated from single thymic clones are phenotypically and functionally heterogeneous.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(6):1877-90.
1988: Harp J A; Tsuchida C B; Weissman I L; Scofield V L
Autoreactive blood cells and programmed cell death in growth and development of protochordates.
The Journal of experimental zoology 1988;247(3):257-62.
1988: McCune J M; Namikawa R; Kaneshima H; Shultz L D; Lieberman M; Weissman I L
The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function.
Science (New York, N.Y.) 1988;241(4873):1632-9.
1988: Weissman I L
Was the MHC made for the immune system, or did immunity take advantage of an ancient polymorphic gene family encoding cell surface interaction molecules? A speculative essay.
International reviews of immunology 1988;3(4):397-416.
1988: Spangrude G J; Heimfeld S; Weissman I L
Purification and characterization of mouse hematopoietic stem cells.
Science (New York, N.Y.) 1988;241(4861):58-62.
1988: Müller-Sieburg C E; Townsend K; Weissman I L; Rennick D
Proliferation and differentiation of highly enriched mouse hematopoietic stem cells and progenitor cells in response to defined growth factors.
The Journal of experimental medicine 1988;167(6):1825-40.
1988: Spangrude G J; Muller-Sieburg C E; Heimfeld S; Weissman I L
Two rare populations of mouse Thy-1lo bone marrow cells repopulate the thymus.
The Journal of experimental medicine 1988;167(5):1671-83.
1988: Adkins B; Gandour D; Strober S; Weissman I
Total lymphoid irradiation leads to transient depletion of the mouse thymic medulla and persistent abnormalities among medullary stromal cells.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(10):3373-9.
1988: Mueller C; Gershenfeld H K; Lobe C G; Okada C Y; Bleackley R C; Weissman I L
Expression of two serine esterase genes during an allograft rejection in the mouse.
Transplantation proceedings 1988;20(2):251-3.
1988: McCune J M; Rabin L B; Feinberg M B; Lieberman M; Kosek J C; Reyes G R; Weissman I L
Endoproteolytic cleavage of gp160 is required for the activation of human immunodeficiency virus.
Cell 1988;53(1):55-67.
1988: Mueller C; Gershenfeld H K; Lobe C G; Okada C Y; Bleackley R C; Weissman I L
A high proportion of T lymphocytes that infiltrate H-2-incompatible heart allografts in vivo express genes encoding cytotoxic cell-specific serine proteases, but do not express the MEL-14-defined lymph node homing receptor.
The Journal of experimental medicine 1988;167(3):1124-36.
1988: Gershenfeld H K; Hershberger R J; Shows T B; Weissman I L
Cloning and chromosomal assignment of a human cDNA encoding a T cell- and natural killer cell-specific trypsin-like serine protease.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(4):1184-8.
1988: Adkins B; Tidmarsh G F; Weissman I L
Normal thymic cortical epithelial cells developmentally regulate the expression of a B-lineage transformation-associated antigen.
Immunogenetics 1988;27(3):180-6.
1988: Sher B T; Bargatze R; Holzmann B; Gallatin W M; Matthews D; Wu N; Picker L; Butcher E C; Weissman I L
Homing receptors and metastasis.
Advances in cancer research 1988;51():361-90.
1988: Gershenfeld H K; Hershberger R J; Mueller C; Weissman I L
A T cell- and natural killer cell-specific, trypsin-like serine protease. Implications of a cytolytic cascade.
Annals of the New York Academy of Sciences 1988;532():367-79.
1987: Lieberman M; Hansteen G A; McCune J M; Scott M L; White J H; Weissman I L
Indirect induction of radiation lymphomas in mice. Evidence for a novel, transmissible leukemogen.
The Journal of experimental medicine 1987;166(6):1883-93.
1987: Bargatze R F; Wu N W; Weissman I L; Butcher E C
High endothelial venule binding as a predictor of the dissemination of passaged murine lymphomas.
The Journal of experimental medicine 1987;166(4):1125-31.
1987: Ezine S; Jerabek L; Weissman I
The phenotype of thymocytes derived from a single clonogenic precursor.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(7):2195-9.
1987: Whitlock C A; Tidmarsh G F; Muller-Sieburg C; Weissman I L
Bone marrow stromal cell lines with lymphopoietic activity express high levels of a pre-B neoplasia-associated molecule.
Cell 1987;48(6):1009-21.
1987: Morse H C; Tidmarsh G F; Holmes K L; Frederickson T F; Hartley J N; Pierce J H; Langdon W Y; Dailey M O; Weissman I L
Expression of the 6C3 antigen on murine hematopoietic neoplasms. Association with expression of abl, ras, fes, src, erbB, and Cas NS-1 oncogenes but not with myc.
The Journal of experimental medicine 1987;165(3):920-5.
1987: Tamura G S; McGrath M S; Weissman I L
Molecules recognized by anti-idiotypic monoclonal antibodies to the B cell lymphoma, BCL1.
The Journal of molecular and cellular immunology : JMCI 1987;3(4):243-53.
1986: Tidmarsh G F; Dailey M O; Weissman I L
Expression of a monoclonal antibody-defined, B-lineage transformation antigen specifically identifies Abelson-diseased animals. Genetically determined resistance to Abelson murine leukemia virus acts before induction of gp160(6C3).
The Journal of experimental medicine 1986;164(4):1356-61.
1986: Razzeca K J; Pillemer E; Weissman I L; Rouse R V
In situ identification of idiotype-positive cells participating in the immune response to phosphorylcholine.
European journal of immunology 1986;16(4):393-9.
1986: Muller-Sieburg C E; Whitlock C A; Weissman I L
Isolation of two early B lymphocyte progenitors from mouse marrow: a committed pre-pre-B cell and a clonogenic Thy-1-lo hematopoietic stem cell.
Cell 1986;44(4):653-62.
1986: Pillemer E A; Kooistra D A; Witte O N; Weissman I L
Monoclonal antibody to the amino-terminal L sequence of murine leukemia virus glycosylated gag polyproteins demonstrates their unusual orientation in the cell membrane.
Journal of virology 1986;57(2):413-21.
1985: Tidmarsh G F; Dailey M O; Whitlock C A; Pillemer E; Weissman I L
Transformed lymphocytes from Abelson-diseased mice express levels of a B lineage transformation-associated antigen elevated from that found on normal lymphocytes.
The Journal of experimental medicine 1985;162(5):1421-34.
1985: Dailey M O; Gallatin W M; Kraal G; Butcher E; Weissman I
T cell clones: a model of a non-recirculating phase of T cell differentiation.
Advances in experimental medicine and biology 1985;186():621-7.
1985: Dailey M O; Gallatin W M; Weissman I L
The in vivo behavior of T cell clones: altered migration due to loss of the lymphocyte surface homing receptor.
The Journal of molecular and cellular immunology : JMCI 1985;2(1):27-36.
1984: Pillemer E; Whitlock C; Weissman I L
Transformation-associated proteins in murine B-cell lymphomas that are distinct from Abelson virus gene products.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(14):4434-8.
1983: Coffman R L; Weissman I L
Immunoglobulin gene rearrangement during pre-B cell differentiation.
The Journal of molecular and cellular immunology : JMCI 1983;1(1):31-41.
1982: Dailey M O; Pillemer E; Weissman I L
Protection against syngeneic lymphoma by a long-lived cytotoxic T-cell clone.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(17):5384-7.
1982: Dailey M O; Fathman C G; Butcher E C; Pillemer E; Weissman I
Abnormal migration of T lymphocyte clones.
Journal of immunology (Baltimore, Md. : 1950) 1982;128(5):2134-6.
1981: Hollander N; Pillemer E; Weissman I L
Effects of Lyt antibodies on T-cell functions: augmentation by anti-Lyt-1 as opposed to inhibition by anti-Lyt-2.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(2):1148-51.
1981: McGrath M S; Jerabek L; Pillemer E; Steinberg R A; Weissman I L
Receptor mediated murine leukemogenesis: monoclonal antibody induced lymphoma cell growth arrest.
Haematology and blood transfusion 1981;26():360-4.
1980: Hollander N; Pillemer E; Weissman I L
Blocking effect of lyt-2 antibodies on T cell functions.
The Journal of experimental medicine 1980;152(3):674-87.
1980: Scollay R; Jacobs S; Jerabek L; Butcher E; Weissman I
T cell maturation: thymocyte and thymus migrant subpopulations defined with monoclonal antibodies to MHC region antigens.
Journal of immunology (Baltimore, Md. : 1950) 1980;124(6):2845-53.
1980: McGrath M S; Pillemer E; Weissman I L
Murine leukaemogenesis: monoclonal antibodies to T-cell determinants arrest T-lymphoma cell proliferation.
Nature 1980;285(5762):259-61.
1980: McGrath M S; Pillemer E; Kooistra D A; Jacobs S; Jerabek L; Weissman I L
T-lymphoma retroviral receptors and control of T-lymphoma cell proliferation.
Cold Spring Harbor symposia on quantitative biology 1980;44 Pt 2,():1297-304.
1980: McGrath M S; Pillemer E; Kooistra D; Weissman I L
The role of MuLV receptors on T-lymphoma cells in lymphoma cell proliferation.
Contemporary topics in immunobiology 1980;11():157-84.

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