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Irving Weissman

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Matthew A Inlay; Irving L Weissman; Nathaniel B Fernhoff; James R Baker; Sophia Bharathi; Veronica Choe; Seok Ki Choi
Synthesis of a photocaged tamoxifen for light-dependent activation of Cre-ER recombinase-driven gene modification.
Reza Ardehali; Timothy A Blauwkamp; Michael Q Chen; Micha Drukker; Yongquan Gong; Matthew A Inlay; Roeland Nusse; Oscar J Abilez; Shah R Ali; Masayuki Yazawa; Irving L Weissman
Prospective isolation of human embryonic stem cell-derived cardiovascular progenitors that integrate into human fetal heart tissue.
Wendy W Pang; Christopher Y Park; John V Pluvinage; Elizabeth A Price; Stanley L Schrier; Kunju Sridhar; Daniel A Arber; Peter L Greenberg; Irving L Weissman
Hematopoietic stem cell and progenitor cell mechanisms in myelodysplastic syndromes.

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2013: Matthew A Inlay; Irving L Weissman; Nathaniel B Fernhoff; James R Baker; Sophia Bharathi; Veronica Choe; Seok Ki Choi
Synthesis of a photocaged tamoxifen for light-dependent activation of Cre-ER recombinase-driven gene modification.
Chemical communications (Cambridge, England) 2013;49(43):4971-3.
2013: Reza Ardehali; Timothy A Blauwkamp; Michael Q Chen; Micha Drukker; Yongquan Gong; Matthew A Inlay; Roeland Nusse; Oscar J Abilez; Shah R Ali; Masayuki Yazawa; Irving L Weissman
Prospective isolation of human embryonic stem cell-derived cardiovascular progenitors that integrate into human fetal heart tissue.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(9):3405-10.
2013: Wendy W Pang; Christopher Y Park; John V Pluvinage; Elizabeth A Price; Stanley L Schrier; Kunju Sridhar; Daniel A Arber; Peter L Greenberg; Irving L Weissman
Hematopoietic stem cell and progenitor cell mechanisms in myelodysplastic syndromes.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(8):3011-6.
2013: Yuval Rinkevich; Amalia Rosner; Ayelet Voskoboynik; Irving L Weissman; Gilad Alfassi; Jacob Douek; Katherine J Ishizuka; Elizabeth Moiseeva; Matan Oren; Karla J Palmeri; Guy Paz; Claudette Rabinowitz; Baruch Rinkevich
Repeated, long-term cycling of putative stem cells between niches in a basal chordate.
Developmental cell 2013;24(1):76-88.
2012: Karl G Blume; Irving L Weissman
E. Donnall Thomas (1920-2012).
Proceedings of the National Academy of Sciences of the United States of America 2012;109(51):20777-8.
2012: Benjamin Levi; David D Lo; Charles K F Chan; Andrew J Connolly; Monica Grova; Geoffrey C Gurtner; Shijun Hu; Jeong S Hyun; Min Lee; Daniel T Montoro; Ning Sun; Derrick C Wan; Irving L Weissman; Joseph C Wu; Michael T Longaker
In vivo directed differentiation of pluripotent stem cells for skeletal regeneration.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(50):20379-84.
2012: Yuval Rinkevich; Debashis Sahoo; John R Bermingham; Taisuke Mori; Pin-Xian Xu; Irving L Weissman
Identification and prospective isolation of a mesothelial precursor lineage giving rise to smooth muscle cells and fibroblasts for mammalian internal organs, and their vasculature.
Nature cell biology 2012;14(12):1251-60.
2012: Aaron C Logan; Irving L Weissman; Judith A Shizuru
The road to purified hematopoietic stem cell transplants is paved with antibodies.
Current opinion in immunology 2012;24(5):640-8.
2012: Natesh Parashurama; Bryan R Smith; Irving L Weissman; Maider Zabala; Frezghi G Habte; Ken Ito; Jessica Lam; Neethan A Lobo; Adriane R Mosley; Michael F Clarke; Sanjiv S Gambhir
Remodeling of endogenous mammary epithelium by breast cancer stem cells.
Stem cells (Dayton, Ohio) 2012;30(10):2114-27.
2012: Max Jan; M Ryan Corces-Zimmerman; Stephen R Quake; Thomas M Snyder; Paresh Vyas; Irving L Weissman; Ravindra Majeti
Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia.
Science translational medicine 2012;4(149):149ra118.
2012: Micha Drukker; Andrew S Lee; Adriane R Mosley; Yuval Rinkevich; Jun Seita; Chad Tang; Irving L Weissman; Reza Ardehali; Yoav Soen
Isolation of primitive endoderm, mesoderm, vascular endothelial and trophoblast progenitors from human pluripotent stem cells.
Nature biotechnology 2012;30(6):531-42.
2012: Mark P Chao; Irving L Weissman; Ravindra Majeti
The CD47-SIRPα pathway in cancer immune evasion and potential therapeutic implications.
Current opinion in immunology 2012;24(2):225-32.
2012: Jens-Peter Volkmer; Irving L Weissman; Stephen B Willingham; Ash A Alizadeh; Andrew H Beck; Robert K Chin; Benjamin I Chung; Humberto Contreras-Trujillo; Guilherme Godoy; Philip Levy Ho; Antonina V Kurtova; Seth P Lerner; Yair Lotan; SENTHIL KUMAR PAZHANISAMY; Debashis Sahoo; Linda D Shortliffe; Theresa A Storm; Chad Tang; Matt van de Rijn; Keith S Chan
Three differentiation states risk-stratify bladder cancer into distinct subtypes.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(6):2078-83.
2012: Timothy A Blauwkamp; Shelly Nigam; Reza Ardehali; Irving L Weissman; Roel Nusse
Endogenous Wnt signalling in human embryonic stem cells generates an equilibrium of distinct lineage-specified progenitors.
Nature communications 2012;3():1070.
2012: Jun Seita; Thomas Serwold; Deepta Bhattacharya; David L Dill; Lauren I R Ehrlich; John W Fathman; Matthew A Inlay; Derrick J Rossi; Debashis Sahoo; Irving L Weissman
Gene Expression Commons: an open platform for absolute gene expression profiling.
PloS one 2012;7(7):e40321.
2012: Chad Tang; Irving L Weissman; Micha Drukker
The safety of embryonic stem cell therapy relies on teratoma removal.
Oncotarget 2012;3(1):7-8.
2011: John W Fathman; Matthew A Inlay; Holger Karsunky; Jun Seita; Deepta Bhattacharya; Irving L Weissman
Identification of the earliest natural killer cell-committed progenitor in murine bone marrow.
Blood 2011;118(20):5439-47.
2011: Mark P Chao; Robert Chin; Ravindra Majeti; Russell K Pachynski; Chad Tang; Irving L Weissman
Extranodal dissemination of non-Hodgkin lymphoma requires CD47 and is inhibited by anti-CD47 antibody therapy.
Blood 2011;118(18):4890-901.
2011: Garrett C Heffner; Garry P Nolan; Matthew R Clutter; Irving L Weissman
Novel hematopoietic progenitor populations revealed by direct assessment of GATA1 protein expression and cMPL signaling events.
Stem cells (Dayton, Ohio) 2011;29(11):1774-82.
2011: Rong Lu; Norma F Neff; Stephen R Quake; Irving L Weissman
Tracking single hematopoietic stem cells in vivo using high-throughput sequencing in conjunction with viral genetic barcoding.
Nature biotechnology 2011;29(10):928-33.
2011: Chad Tang; Jens-Peter Volkmer; Irving L Weissman; Joseph C Wu; Reza Ardehali; Barry Behr; Shawn L Chavez; Matthew A Inlay; Andrew S Lee; Adriane R Mosley; Divya Nag; Renee Reijo Pera; Debashis Sahoo; Micha Drukker
An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells.
Nature biotechnology 2011;29(9):829-34.
2011: Yuval Rinkevich; Hiroo Ueno; Paul Lindau; Michael T Longaker; Irving L Weissman
Germ-layer and lineage-restricted stem/progenitors regenerate the mouse digit tip.
Nature 2011;476(7361):409-13.
2011: Reza Ardehali; Matthew A Inlay; Adriane R Mosley; Shah R Ali; Irving L Weissman
Enhanced survival of pluripotent stem cells under stressful conditions.
Cell cycle (Georgetown, Tex.) 2011;10(16):2610-1.
2011: Kenneth D Gibbs; Penney M Gilbert; Karen Sachs; Feifei Zhao; Helen M Blau; Irving L Weissman; Garry P Nolan; Ravindra Majeti
Single-cell phospho-specific flow cytometric analysis demonstrates biochemical and functional heterogeneity in human hematopoietic stem and progenitor compartments.
Blood 2011;117(16):4226-33.
2011: Max Jan; Mark P Chao; Adriel C Cha; Ash A Alizadeh; Andrew Gentles; Irving L Weissman; Ravindra Majeti
Prospective separation of normal and leukemic stem cells based on differential expression of TIM3, a human acute myeloid leukemia stem cell marker.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(12):5009-14.
2011: Lauren I Richie Ehrlich; Thomas Serwold; Irving L Weissman
In vitro assays misrepresent in vivo lineage potentials of murine lymphoid progenitors.
Blood 2011;117(9):2618-24.
2011: Reza Ardehali; Matthew A Inlay; Shah R Ali; Chad Tang; Micha Drukker; Irving L Weissman
Overexpression of BCL2 enhances survival of human embryonic stem cells during stress and obviates the requirement for serum factors.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(8):3282-7.
2011: Irving L Weissman
50 years later: remembering the paper.
Radiation research 2011;175(2):143-4.
2011: Agnieszka Czechowicz; Irving L Weissman
Purified hematopoietic stem cell transplantation: the next generation of blood and immune replacement.
Hematology/oncology clinics of North America 2011;25(1):75-87.
2011: Olga V Razorenova; Elizabeth C Finger; Renata Colavitti; Sophia B Chernikova; Alexander D Boiko; Charles K F Chan; Adam Krieg; Barbara Bedogni; Edward LaGory; Irving L Weissman; Marianne Broome-Powell; Amato J Giaccia
VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKC{delta}-driven migration.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(5):1931-6.
2011: Ravindra Majeti; Irving L Weissman
Human acute myelogenous leukemia stem cells revisited: there's more than meets the eye.
Cancer cell 2011;19(1):9-10.
2010: Mark P Chao; Siddhartha Jaiswal; Rachel Weissman-Tsukamoto; Ash A Alizadeh; Andrew J Gentles; Jens Volkmer; Kipp Weiskopf; Stephen B Willingham; Tal Raveh; Christopher Y Park; Ravindra Majeti; Irving L Weissman
Calreticulin is the dominant pro-phagocytic signal on multiple human cancers and is counterbalanced by CD47.
Science translational medicine 2010;2(63):63ra94.
2010: A G Lisa Ooi; Debashis Sahoo; Maddalena Adorno; Yulei Wang; Irving L Weissman; Christopher Y Park
MicroRNA-125b expands hematopoietic stem cells and enriches for the lymphoid-balanced and lymphoid-biased subsets.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(50):21505-10.
2010: Thomas Serwold; Konrad Hochedlinger; John Swindle; Joe Hedgpeth; Rudolf Jaenisch; Irving L Weissman
T-cell receptor-driven lymphomagenesis in mice derived from a reprogrammed T cell.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(44):18939-43.
2010: Jun Seita; Irving L Weissman
Hematopoietic stem cell: self-renewal versus differentiation.
Wiley interdisciplinary reviews. Systems biology and medicine 2010;2(6):640-53.
2010: Edwin Chang; E Camilla Forsberg; Jenny Wu; Susan S Prohaska; Rich Allsopp; Irving L Weissman; John P Cooke
Cholinergic activation of hematopoietic stem cells: role in tobacco-related disease?
Vascular medicine (London, England) 2010;15(5):375-85.
2010: Hong Ji; Lauren I R Ehrlich; Jun Seita; Peter Murakami; Akiko Doi; Paul Lindau; Hwajin Lee; Martin Aryee; Rafael A Irizarry; Kitai Kim; Derrick J Rossi; Matthew A Inlay; Thomas Serwold; Holger Karsunky; Lena Ho; George Q Daley; Irving L Weissman; Andrew P Feinberg
Comprehensive methylome map of lineage commitment from haematopoietic progenitors.
Nature 2010;467(7313):338-42.
2010: Mark P Chao; Ash A Alizadeh; Chad Tang; June H Myklebust; Bindu Varghese; Saar Gill; Max Jan; Adriel C Cha; Charles K Chan; Brent T Tan; Christopher Park; Feifei Zhao; Holbrook E Kohrt; Raquel Malumbres; Javier Briones; Randy D Gascoyne; Izidore S Lossos; Ronald Levy; Irving L Weissman; Ravindra Majeti
Anti-CD47 antibody synergizes with rituximab to promote phagocytosis and eradicate non-Hodgkin lymphoma.
Cell 2010;142(5):699-713.
2010: Jun Seita; Derrick J Rossi; Irving L Weissman
Differential DNA damage response in stem and progenitor cells.
Cell stem cell 2010;7(2):145-7.
2010: Alexander D Boiko; Olga V Razorenova; Matt van de Rijn; Susan M Swetter; Denise L Johnson; Daphne P Ly; Paris D Butler; George P Yang; Benzion Joshua; Michael J Kaplan; Michael T Longaker; Irving L Weissman
Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271.
Nature 2010;466(7302):133-7.
2010: Siddhartha Jaiswal; Mark P Chao; Ravindra Majeti; Irving L Weissman
Macrophages as mediators of tumor immunosurveillance.
Trends in immunology 2010;31(6):212-9.
2010: Agnieszka Czechowicz; Irving L Weissman
Purified hematopoietic stem cell transplantation: the next generation of blood and immune replacement.
Immunology and allergy clinics of North America 2010;30(2):159-71.
2010: Christopher B Franco; Ching-Cheng Chen; Micha Drukker; Irving L Weissman; Stephen J Galli
Distinguishing mast cell and granulocyte differentiation at the single-cell level.
Cell stem cell 2010;6(4):361-8.
2010: Debashis Sahoo; Jun Seita; Deepta Bhattacharya; Matthew A Inlay; Irving L Weissman; Sylvia K Plevritis; David L Dill
MiDReG: a method of mining developmentally regulated genes using Boolean implications.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(13):5732-7.
2010: Hiroo Ueno; Irving L Weissman
The origin and fate of yolk sac hematopoiesis: application of chimera analyses to developmental studies.
The International journal of developmental biology 2010;54(6-7):1019-31.
2009: Lauren I Richie Ehrlich; David Y Oh; Irving L Weissman; Richard S Lewis
Differential contribution of chemotaxis and substrate restriction to segregation of immature and mature thymocytes.
Immunity 2009;31(6):986-98.
2009: Peter Papathanasiou; Joanne L Attema; Holger Karsunky; Naoki Hosen; Yovina Sontani; Gerard F Hoyne; Robert Tunningley; Stephen T Smale; Irving L Weissman
Self-renewal of the long-term reconstituting subset of hematopoietic stem cells is regulated by Ikaros.
Stem cells (Dayton, Ohio) 2009;27(12):3082-92.
2009: Deepta Bhattacharya; Agnieszka Czechowicz; A G Lisa Ooi; Derrick J Rossi; David Bryder; Irving L Weissman
Niche recycling through division-independent egress of hematopoietic stem cells.
The Journal of experimental medicine 2009;206(12):2837-50.
2009: Matthew A Inlay; Deepta Bhattacharya; Debashis Sahoo; Thomas Serwold; Jun Seita; Holger Karsunky; Sylvia K Plevritis; David L Dill; Irving L Weissman
Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development.
Genes & development 2009;23(20):2376-81.
2009: Peter Papathanasiou; Joanne L Attema; Holger Karsunky; Jian Xu; Stephen T Smale; Irving L Weissman
Evaluation of the long-term reconstituting subset of hematopoietic stem cells with CD150.
Stem cells (Dayton, Ohio) 2009;27(10):2498-508.
2009: Mayumi Yamada; Paul T Gurney; Jaehoon Chung; Pratima Kundu; Micha Drukker; Alan K Smith; Irving L Weissman; Dwight Nishimura; Robert C Robbins; Phillip C Yang
Manganese-guided cellular MRI of human embryonic stem cell and human bone marrow stromal cell viability.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2009;62(4):1047-54.
2009: Siddhartha Jaiswal; Irving L Weissman
Hematopoietic stem and progenitor cells and the inflammatory response.
Annals of the New York Academy of Sciences 2009;1174():118-21.
2009: Keith Syson Chan; Inigo Espinosa; Mark Chao; David Wong; Laurie Ailles; Maximilian Diehn; Harcharan Gill; Joseph Presti; Howard Y Chang; Matt van de Rijn; Linda Shortliffe; Irving L Weissman
Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(33):14016-21.
2009: Samuel Cheshier; M Yashar S Kalani; Michael Lim; Laurie Ailles; Stephen L Huhn; Irving L Weissman
A neurosurgeon's guide to stem cells, cancer stem cells, and brain tumor stem cells.
Neurosurgery 2009;65(2):237-49; discussion 249-50; quiz N6.
2009: Ravindra Majeti; Mark P Chao; Ash A Alizadeh; Wendy W Pang; Siddhartha Jaiswal; Kenneth D Gibbs; Nico van Rooijen; Irving L Weissman
CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells.
Cell 2009;138(2):286-99.
2009: Siddhartha Jaiswal; Catriona H M Jamieson; Wendy W Pang; Christopher Park; Mark P Chao; Ravindra Majeti; David Traver; Nico van Rooijen; Irving L Weissman
CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis.
Cell 2009;138(2):271-85.
2009: Toshiyuki Yamane; Naoki Hosen; Hidetoshi Yamazaki; Irving L Weissman
Expression of AA4.1 marks lymphohematopoietic progenitors in early mouse development.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(22):8953-8.
2009: Akifumi Ootani; Xingnan Li; Eugenio Sangiorgi; Quoc T Ho; Hiroo Ueno; Shuji Toda; Hajime Sugihara; Kazuma Fujimoto; Irving L Weissman; Mario R Capecchi; Calvin J Kuo
Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche.
Nature medicine 2009;15(6):701-6.
2009: Angela R Wu; Joseph B Hiatt; Rong Lu; Joanne L Attema; Neethan A Lobo; Irving L Weissman; Michael F Clarke; Stephen R Quake
Automated microfluidic chromatin immunoprecipitation from 2,000 cells.
Lab on a chip 2009;9(10):1365-70.
2009: Maximilian Diehn; Robert W Cho; Neethan A Lobo; Tomer Kalisky; Mary Jo Dorie; Angela N Kulp; Dalong Qian; Jessica S Lam; Laurie Ailles; Manzhi Wong; Benzion Joshua; Michael J Kaplan; Irene Wapnir; Frederick M Dirbas; George Somlo; Carlos Garberoglio; Benjamin Paz; Jeannie Shen; Sean K Lau; Stephen R Quake; J Martin Brown; Irving L Weissman; Michael F Clarke
Association of reactive oxygen species levels and radioresistance in cancer stem cells.
Nature 2009;458(7239):780-3.
2009: Annelie E Abrahamsson; Ifat Geron; Jason Gotlib; Kim-Hien T Dao; Charlene F Barroga; Isabel G Newton; Francis Giles; Jeffrey A Durocher; Remi S Creusot; Mobin Karimi; Carol Jones; James L Zehnder; Armand Keating; Robert S Negrin; Irving L Weissman; Catriona H M Jamieson
Glycogen synthase kinase 3beta missplicing contributes to leukemia stem cell generation.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(10):3925-9.
2009: Ravindra Majeti; Michael W Becker; Qiang Tian; Tsung-Lu Michael Lee; Xiaowei Yan; Rui Liu; Jung-Hsien Chiang; Leroy Hood; Michael F Clarke; Irving L Weissman
Dysregulated gene expression networks in human acute myelogenous leukemia stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(9):3396-401.
2009: A G Lisa Ooi; Holger Karsunky; Ravindra Majeti; Stefan Butz; Dietmar Vestweber; Tatsuro Ishida; Thomas Quertermous; Irving L Weissman; E Camilla Forsberg
The adhesion molecule esam1 is a novel hematopoietic stem cell marker.
Stem cells (Dayton, Ohio) 2009;27(3):653-61.
2009: Xiaoyan Xie; Keith S Chan; Feng Cao; Mei Huang; Zongjin Li; Andrew Lee; Irving L Weissman; Joseph C Wu
Imaging of STAT3 signaling pathway during mouse embryonic stem cell differentiation.
Stem cells and development 2009;18(2):205-14.
2009: Craig L Semerad; Elinore M Mercer; Matthew A Inlay; Irving L Weissman; Cornelis Murre
E2A proteins maintain the hematopoietic stem cell pool and promote the maturation of myelolymphoid and myeloerythroid progenitors.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(6):1930-5.
2009: Christopher Park; Diane Tseng; Irving L Weissman
Cancer stem cell-directed therapies: recent data from the laboratory and clinic.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(2):219-30.
2009: Charles K F Chan; Ching-Cheng Chen; Cynthia A Luppen; Jae-Beom Kim; Anthony T DeBoer; Kevin Wei; Jill A Helms; Calvin J Kuo; Daniel L Kraft; Irving L Weissman
Endochondral ossification is required for haematopoietic stem-cell niche formation.
Nature 2009;457(7228):490-4.
2009: Thomas Serwold; L I R Ehrlich; Irving L Weissman
Reductive isolation from bone marrow and blood implicates common lymphoid progenitors as the major source of thymopoiesis.
Blood 2009;113(4):807-15.
2009: Hiroo Ueno; Brit B Turnbull; Irving L Weissman
Two-step oligoclonal development of male germ cells.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(1):175-80.
2009: Zongjin Li; Kitchener D Wilson; Bryan Smith; Daniel L Kraft; Fangjun Jia; Mei Huang; Xiaoyan Xie; Robert C Robbins; Sanjiv S Gambhir; Irving L Weissman; Joseph C Wu
Functional and transcriptional characterization of human embryonic stem cell-derived endothelial cells for treatment of myocardial infarction.
PloS one 2009;4(12):e8443.
2008: Yoriyasu Suzuki; Charle H Cunningham; Ken-ichiro Noguchi; Ian Y Chen; Irving L Weissman; Alan C Yeung; Robert C Robbins; Phillip C Yang
In vivo serial evaluation of superparamagnetic iron-oxide labeled stem cells by off-resonance positive contrast.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2008;60(6):1269-75.
2008: Yu-An Cao; Amy J Wagers; Holger Karsunky; Hui Zhao; Robert Reeves; Ronald J Wong; David K Stevenson; Irving L Weissman; Christopher H Contag
Heme oxygenase-1 deficiency leads to disrupted response to acute stress in stem cells and progenitors.
Blood 2008;112(12):4494-502.
2008: M Yashar S Kalani; Samuel Cheshier; Branden J Cord; Simon R Bababeygy; Hannes Vogel; Irving L Weissman; Theo D Palmer; Roel Nusse
Wnt-mediated self-renewal of neural stem/progenitor cells.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(44):16970-5.
2008: Irving L Weissman; Judith A Shizuru
The origins of the identification and isolation of hematopoietic stem cells, and their capability to induce donor-specific transplantation tolerance and treat autoimmune diseases.
Blood 2008;112(9):3543-53.
2008: Ayelet Voskoboynik; Yoav Soen; Yuval Rinkevich; Amalia Rosner; Hiroo Ueno; Ram Reshef; Katherine J Ishizuka; Karla J Palmeri; Elizabeth Moiseeva; Baruch Rinkevich; Irving L Weissman
Identification of the endostyle as a stem cell niche in a colonial chordate.
Cell stem cell 2008;3(4):456-64.
2008: Patrick Viatour; Tim C Somervaille; Shivkumar Venkatasubrahmanyam; Scott Kogan; Margaret E McLaughlin; Irving L Weissman; Atul J Butte; Emmanuelle Passegué; Julien Sage
Hematopoietic stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family.
Cell stem cell 2008;3(4):416-28.
2008: Stephen L Hendry; Koen van der Bogt; Ahmad Y Sheikh; Takayasu Arai; Scott J Dylla; Micha Drukker; Michael V McConnell; Ingo Kutschka; Grant Hoyt; Feng Cao; Irving L Weissman; Andrew J Connolly; Marc P Pelletier; Joseph C Wu; Robert C Robbins; Phillip C Yang
Multimodal evaluation of in vivo magnetic resonance imaging of myocardial restoration by mouse embryonic stem cells.
The Journal of thoracic and cardiovascular surgery 2008;136(4):1028-1037.e1.
2008: Roi Gazit; Irving L Weissman; Derrick J Rossi
Hematopoietic stem cells and the aging hematopoietic system.
Seminars in hematology 2008;45(4):218-24.
2008: Deepta Bhattacharya; Lauren I Richie Ehrlich; Irving L Weissman
Space-time considerations for hematopoietic stem cell transplantation.
European journal of immunology 2008;38(8):2060-7.
2008: Irving L Weissman
The E. Donnall Thomas lecture: normal and neoplastic stem cells.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2008;14(8):849-58.
2008: Holger Karsunky; Matthew A Inlay; Thomas Serwold; Deepta Bhattacharya; Irving L Weissman
Flk2+ common lymphoid progenitors possess equivalent differentiation potential for the B and T lineages.
Blood 2008;111(12):5562-70.
2008: Anming Xiong; Timothy W Austin; Eric Lagasse; Nobuko Uchida; Stanley Tamaki; Bruno B Bordier; Irving L Weissman; Jeffrey S Glenn; Maria T Millan
Isolation of human fetal liver progenitors and their enhanced proliferation by three-dimensional coculture with endothelial cells.
Tissue engineering. Part A 2008;14(6):995-1006.
2008: Susanna Lauttia (neé Purhonen); Jarmo Palm; Derrick Rossi; Nina Kaskenpää; Iiro Rajantie; Seppo Ylä-Herttuala; Kari Alitalo; Irving L Weissman; Petri Salven
Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growth.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(18):6620-5.
2008: Derrick J Rossi; Catriona H M Jamieson; Irving L Weissman
Stems cells and the pathways to aging and cancer.
Cell 2008;132(4):681-96.
2008: Simon R Bababeygy; Samuel Cheshier; Lewis C Hou; Dominique M O Higgins; Irving L Weissman; victor Tse
Hematopoietic stem cell-derived pericytic cells in brain tumor angio-architecture.
Stem cells and development 2008;17(1):11-8.
2008: M P Chao; Jun Seita; Irving L Weissman
Establishment of a normal hematopoietic and leukemia stem cell hierarchy.
Cold Spring Harbor symposia on quantitative biology 2008;73():439-49.
2008: Feng Cao; Roger A Wagner; Kitchener D Wilson; Xiaoyan Xie; Ji-Dong Fu; Micha Drukker; Andrew Lee; Ronald A Li; Sanjiv S Gambhir; Irving L Weissman; Robert C Robbins; Joseph C Wu
Transcriptional and functional profiling of human embryonic stem cell-derived cardiomyocytes.
PloS one 2008;3(10):e3474.
2008: Jason Beliakoff; Jane Lee; Hiroo Ueno; Aparna Aiyer; Irving L Weissman; Gregory S Barsh; Robert Cardiff; Zijie Sun
The PIAS-like protein Zimp10 is essential for embryonic viability and proper vascular development.
Molecular and cellular biology 2008;28(1):282-92.
2007: Ravindra Majeti; Christopher Park; Irving L Weissman
Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood.
Cell stem cell 2007;1(6):635-45.
2007: Luigi A Warren; Derrick J Rossi; Geoffrey R Schiebinger; Irving L Weissman; Stuart K Kim; Stephen R Quake
Transcriptional instability is not a universal attribute of aging.
Aging cell 2007;6(6):775-82.
2007: Agnieszka Czechowicz; Daniel Kraft; Irving L Weissman; Deepta Bhattacharya
Efficient transplantation via antibody-based clearance of hematopoietic stem cell niches.
Science (New York, N.Y.) 2007;318(5854):1296-9.
2007: Deepta Bhattacharya; Ming T Cheah; Christopher B Franco; Naoki Hosen; Christopher L Pin; William C Sha; Irving L Weissman
Transcriptional profiling of antigen-dependent murine B cell differentiation and memory formation.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(10):6808-19.
2007: Cornelis J H Pronk; Derrick J Rossi; Robert Månsson; Joanne L Attema; Gudmundur Logi Norddahl; Charles Kwok Fai Chan; Mikael Sigvardsson; Irving L Weissman; David Bryder
Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy.
Cell stem cell 2007;1(4):428-42.
2007: Laurie Ailles; Irving L Weissman
Cancer stem cells in solid tumors.
Current opinion in biotechnology 2007;18(5):460-6.
2007: Samuel Cheshier; Prohaska Susan; Irving L Weissman
The effect of bleeding on hematopoietic stem cell cycling and self-renewal.
Stem cells and development 2007;16(5):707-17.
2007: Derrick J Rossi; Jun Seita; Agnieszka Czechowicz; Deepta Bhattacharya; David Bryder; Irving L Weissman
Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during aging.
Cell cycle (Georgetown, Tex.) 2007;6(19):2371-6.
2007: Naoki Hosen; Toshiaki Shirakata; Sumiyuki Nishida; Masashi Yanagihara; Akihiro Tsuboi; Manabu Kawakami; Yusuke Oji; Yoshihiro Oka; M Okabe; B Tan; Haruo Sugiyama; Irving L Weissman
The Wilms' tumor gene WT1-GFP knock-in mouse reveals the dynamic regulation of WT1 expression in normal and leukemic hematopoiesis.
Leukemia 2007;21(8):1783-91.
2007: Joanne L Attema; Peter Papathanasiou; Camilla Forsberg; Jian Xu; Stephen T Smale; Irving L Weissman
Epigenetic characterization of hematopoietic stem cell differentiation using miniChIP and bisulfite sequencing analysis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(30):12371-6.
2007: Jian Xu; Scott D Pope; Ali R Jazirehi; Joanne L Attema; Peter Papathanasiou; Jason A Watts; Kenneth S Zaret; Irving L Weissman; Stephen T Smale
Pioneer factor interactions and unmethylated CpG dinucleotides mark silent tissue-specific enhancers in embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(30):12377-82.
2007: Thomas Serwold; Konrad Hochedlinger; Matthew A Inlay; Rudolf Jaenisch; Irving L Weissman
Early TCR expression and aberrant T cell development in mice with endogenous prerearranged T cell receptor genes.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(2):928-38.
2007: Naoki Hosen; Toshiyuki Yamane; Manja Muijtjens; Kara Pham; Michael F Clarke; Irving L Weissman
Bmi-1-green fluorescent protein-knock-in mice reveal the dynamic regulation of bmi-1 expression in normal and leukemic hematopoietic cells.
Stem cells (Dayton, Ohio) 2007;25(7):1635-44.
2007: Naoki Hosen; Christopher Park; Naoya Tatsumi; Yusuke Oji; Haruo Sugiyama; Martin Gramatzki; Alan Krensky; Irving L Weissman
CD96 is a leukemic stem cell-specific marker in human acute myeloid leukemia.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(26):11008-13.
2007: Derrick J Rossi; David Bryder; Jun Seita; Andre Nussenzweig; Jan H J Hoeijmakers; Irving L Weissman
Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age.
Nature 2007;447(7145):725-9.
2007: Mrinmoy Sanyal; James W Tung; Holger Karsunky; Hong Zeng; Licia Selleri; Irving L Weissman; Leonore A Herzenberg; Michael L Cleary
B-cell development fails in the absence of the Pbx1 proto-oncogene.
Blood 2007;109(10):4191-9.
2007: Ayelet Voskoboynik; Noa Simon-Blecher; Yoav Soen; Baruch Rinkevich; Anthony W de Tomaso; Katherine J Ishizuka; Irving L Weissman
Striving for normality: whole body regeneration through a series of abnormal generations.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(7):1335-44.
2007: Derrick J Rossi; David Bryder; Irving L Weissman
Hematopoietic stem cell aging: mechanism and consequence.
Experimental gerontology 2007;42(5):385-90.
2007: Marta Serafini; Scott J Dylla; Masayuki Oki; Yves Heremans; Jakub Tolar; Yuehua Jiang; Shannon M Buckley; Beatriz Pelacho; Terry C Burns; Sarah Frommer; Derrick J Rossi; David Bryder; Angela Panoskaltsis-Mortari; Matthew J O'Shaughnessy; Molly Nelson-Holte; Gabriel C Fine; Irving L Weissman; Bruce R Blazar; Catherine M Verfaillie
Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells.
The Journal of experimental medicine 2007;204(1):129-39.
2007: Mark E Prince; Ranjiv Sivanandan; A Kaczorowski; Gregory T Wolf; Michael J Kaplan; Piero Dalerba; Irving L Weissman; Michael F Clarke; L E Ailles
Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(3):973-8.
2007: Micha Drukker; Christina Muscat; Irving L Weissman
Generation of a monoclonal antibody library against human embryonic stem cells.
Methods in molecular biology (Clifton, N.J.) 2007;407():63-81.
2007: Feng Cao; Micha Drukker; Shuan Lin; Ahmad Y Sheikh; Xiaoyan Xie; Zongjin Li; Andrew J Connolly; Irving L Weissman; Joseph C Wu
Molecular imaging of embryonic stem cell misbehavior and suicide gene ablation.
Cloning and stem cells 2007;9(1):107-17.
2006: Brenton Thomas Tan; Christopher Park; Laurie Ailles; Irving L Weissman
The cancer stem cell hypothesis: a work in progress.
Laboratory investigation; a journal of technical methods and pathology 2006;86(12):1203-7.
2006: Luigi Warren; David Bryder; Irving L Weissman; Stephen R Quake
Transcription factor profiling in individual hematopoietic progenitors by digital RT-PCR.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(47):17807-12.
2006: Hiroo Ueno; Irving L Weissman
Clonal analysis of mouse development reveals a polyclonal origin for yolk sac blood islands.
Developmental cell 2006;11(4):519-33.
2006: Michael F Clarke; John E Dick; Peter B Dirks; Connie J Eaves; Catriona H M Jamieson; D Leanne Jones; Jane E Visvader; Irving L Weissman; Geoffrey M Wahl
Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells.
Cancer research 2006;66(19):9339-44.
2006: Justin G Santarelli; Vikram Udani; Yun C Yung; Samuel Cheshier; Amy J Wagers; Rolf Brekken; Irving L Weissman; victor Tse
Incorporation of bone marrow-derived Flk-1-expressing CD34+ cells in the endothelium of tumor vessels in the mouse brain.
Neurosurgery 2006;59(2):374-82; discussion 374-82.
2006: David Bryder; Derrick J Rossi; Irving L Weissman
Hematopoietic stem cells: the paradigmatic tissue-specific stem cell.
The American journal of pathology 2006;169(2):338-46.
2006: Camilla Forsberg; Thomas Serwold; Scott Kogan; Irving L Weissman; Emmanuelle Passegué
New evidence supporting megakaryocyte-erythrocyte potential of flk2/flt3+ multipotent hematopoietic progenitors.
Cell 2006;126(2):415-26.
2006: Spencer V Nyholm; Emmanuelle Passegue; William B Ludington; Ayelet Voskoboynik; Katrina Mitchel; Irving L Weissman; Anthony W de Tomaso
fester, A candidate allorecognition receptor from a primitive chordate.
Immunity 2006;25(1):163-73.
2006: Deepta Bhattacharya; David Bryder; Derrick J Rossi; Irving L Weissman
Rapid lymphocyte reconstitution of unconditioned immunodeficient mice with non-self-renewing multipotent hematopoietic progenitors.
Cell cycle (Georgetown, Tex.) 2006;5(11):1135-9.
2006: Derrick J Rossi; Irving L Weissman
Pten, tumorigenesis, and stem cell self-renewal.
Cell 2006;125(2):229-31.
2006: Catriona H M Jamieson; Jason Gotlib; Jeffrey A Durocher; Mark P Chao; M Rajan Mariappan; Marla Lay; Carol Jones; James L Zehnder; Stan L Lilleberg; Irving L Weissman
The JAK2 V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid differentiation.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(16):6224-9.
2006: Amy J Wagers; Irving L Weissman
Differential expression of alpha2 integrin separates long-term and short-term reconstituting Lin-/loThy1.1(lo)c-kit+ Sca-1+ hematopoietic stem cells.
Stem cells (Dayton, Ohio) 2006;24(4):1087-94.
2006: Feng Cao; Shuan Lin; Xiaoyan Xie; Pritha Ray; Manishkumar Patel; Xianzhong Zhang; Micha Drukker; Scott J Dylla; Andrew J Connolly; Xiaoyuan Chen; Irving L Weissman; Sanjiv S Gambhir; Joseph C Wu
In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery.
Circulation 2006;113(7):1005-14.
2006: Ines Mende; Holger Karsunky; Irving L Weissman; Edgar G Engleman; Miriam Merad
Flk2+ myeloid progenitors are the main source of Langerhans cells.
Blood 2006;107(4):1383-90.
2006: Deepta Bhattacharya; Derrick J Rossi; David Bryder; Irving L Weissman
Purified hematopoietic stem cell engraftment of rare niches corrects severe lymphoid deficiencies without host conditioning.
The Journal of experimental medicine 2006;203(1):73-85.
2006: Chia-Lin Hsu; Angela G King-Fleischman; Anne Y Lai; Yukie Matsumoto; Irving L Weissman; Motonari Kondo
Antagonistic effect of CCAAT enhancer-binding protein-alpha and Pax5 in myeloid or lymphoid lineage choice in common lymphoid progenitors.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(3):672-7.
2006: Camilla Forsberg; Deepta Bhattacharya; Irving L Weissman
Hematopoietic stem cells: expression profiling and beyond.
Stem cell reviews 2006;2(1):23-30.
2005: Diana J Laird; Anthony W de Tomaso; Irving L Weissman
Stem cells are units of natural selection in a colonial ascidian.
Cell 2005;123(7):1351-60.
2005: Emmanuelle Passegué; Amy J Wagers; Sylvie Giuriato; Wade C Anderson; Irving L Weissman
Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates.
The Journal of experimental medicine 2005;202(11):1599-611.
2005: Anthony W de Tomaso; Spencer V Nyholm; Karla J Palmeri; Katherine J Ishizuka; William B Ludington; Katrina Mitchel; Irving L Weissman
Isolation and characterization of a protochordate histocompatibility locus.
Nature 2005;438(7067):454-9.
2005: Stephen L Huhn; Yun C Yung; Samuel Cheshier; Griffith R Harsh; Laurie Ailles; Irving L Weissman; Hannes Vogel; victor Tse
Identification of phenotypic neural stem cells in a pediatric astroblastoma.
Journal of neurosurgery 2005;103(5 Suppl):446-50.
2005: Vikram Udani; Justin G Santarelli; Yun C Yung; Amy J Wagers; Samuel Cheshier; Irving L Weissman; victor Tse
Hematopoietic stem cells give rise to perivascular endothelial-like cells during brain tumor angiogenesis.
Stem cells and development 2005;14(5):478-86.
2005: Marcos E García-Ojeda; Sussan Dejbakhsh-Jones; Devavani Chatterjea-Matthes; Aditi Mukhopadhyay; Andrew BitMansour; Irving L Weissman; Janice M Y Brown; Samuel Strober
Stepwise development of committed progenitors in the bone marrow that generate functional T cells in the absence of the thymus.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(7):4363-73.
2005: Irving L Weissman
Stem cell research: paths to cancer therapies and regenerative medicine.
JAMA : the journal of the American Medical Association 2005;294(11):1359-66.
2005: Camilla Forsberg; Prohaska Susan; Sol Katzman; Garrett C Heffner; Josh M Stuart; Irving L Weissman
Differential expression of novel potential regulators in hematopoietic stem cells.
PLoS genetics 2005;1(3):e28.
2005: Theo Kofidis; Jorg Lucas deBruin; Masashi Tanaka; Monika Zwierzchoniewska; Irving L Weissman; Eugenia V Fedoseyeva; Axel Haverich; Robert C Robbins
They are not stealthy in the heart: embryonic stem cells trigger cell infiltration, humoral and T-lymphocyte-based host immune response.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2005;28(3):461-6.
2005: Ching-Cheng Chen; Michele Grimbaldeston; Mindy Tsai; Irving L Weissman; Stephen J Galli
Identification of mast cell progenitors in adult mice.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(32):11408-13.
2005: Derrick J Rossi; David Bryder; Jacob M Zahn; Henrik Ahlenius; Rebecca Sonu; Amy J Wagers; Irving L Weissman
Cell intrinsic alterations underlie hematopoietic stem cell aging.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(26):9194-9.
2005: Theo Kofidis; Jorg L de Bruin; Toshiyuki Yamane; Masashi Tanaka; Darren R Lebl; Rutger-Jan Swijnenburg; Irving L Weissman; Robert C Robbins
Stimulation of paracrine pathways with growth factors enhances embryonic stem cell engraftment and host-specific differentiation in the heart after ischemic myocardial injury.
Circulation 2005;111(19):2486-93.
2005: Mei Massengale; Amy J Wagers; Hannes Vogel; Irving L Weissman
Hematopoietic cells maintain hematopoietic fates upon entering the brain.
The Journal of experimental medicine 2005;201(10):1579-89.
2005: Erik A Ranheim; Helen C K Kwan; Tannishtha Reya; Yu-Ker Wang; Irving L Weissman; Uta Francke
Frizzled 9 knock-out mice have abnormal B-cell development.
Blood 2005;105(6):2487-94.
2005: Toshiyuki Yamane; Scott J Dylla; Manja Muijtjens; Irving L Weissman
Enforced Bcl-2 expression overrides serum and feeder cell requirements for mouse embryonic stem cell self-renewal.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(9):3312-7.
2005: Irina M Conboy; Michael J Conboy; Amy J Wagers; Eric R Girma; Irving L Weissman; Thomas A Rando
Rejuvenation of aged progenitor cells by exposure to a young systemic environment.
Nature 2005;433(7027):760-4.
2005: Holger Karsunky; Miriam Merad; Ines Mende; Markus G Manz; Edgar G Engleman; Irving L Weissman
Developmental origin of interferon-alpha-producing dendritic cells from hematopoietic precursors.
Experimental hematology 2005;33(2):173-81.
2005: Justin G Santarelli; Vikram Udani; C Y Yung; Samuel Cheshier; Amy J Wagers; Rolf Brekken; Irving L Weissman; victor Tse
Preuss Resident Research Award: bone marrow-derived Flk-1-expressing CD34+ cells contribute to the endothelium of tumor vessels in mouse brain.
Clinical neurosurgery 2005;52():384-8.
2005: Irving L Weissman
Normal and neoplastic stem cells.
Novartis Foundation symposium 2005;265():35-50; discussion 50-4, 92-7.
2004: Erik A Ranheim; Kristin V Tarbell; Michelle Krogsgaard; Valérie Mallet-Designe; Luc Teyton; Hugh McDevitt; Irving L Weissman
Selection of aberrant class II restricted CD8+ T cells in NOD mice expressing a glutamic acid decarboxylase (GAD)65-specific T cell receptor transgene.
Autoimmunity 2004;37(8):555-67.
2004: Yun C Yung; Samuel Cheshier; Justin G Santarelli; Zan Huang; Amy J Wagers; Irving L Weissman; victor Tse
Incorporation of naive bone marrow derived cells into the vascular architecture of brain tumor.
Microcirculation (New York, N.Y. : 1994) 2004;11(8):699-708.
2004: Catriona H M Jamieson; Irving L Weissman; Emmanuelle Passegué
Chronic versus acute myelogenous leukemia: a question of self-renewal.
Cancer cell 2004;6(6):531-3.
2004: Richard I Sherwood; Julie L Christensen; Irina M Conboy; Michael J Conboy; Thomas A Rando; Irving L Weissman; Amy J Wagers
Isolation of adult mouse myogenic progenitors: functional heterogeneity of cells within and engrafting skeletal muscle.
Cell 2004;119(4):543-54.
2004: Emmanuelle Passegué; Erwin F Wagner; Irving L Weissman
JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells.
Cell 2004;119(3):431-43.
2004: Catriona H M Jamieson; Laurie Ailles; Scott J Dylla; Manja Muijtjens; Carol Jones; James L Zehnder; Jason Gotlib; Kevin Li; Markus G Manz; Armand Keating; Charles L Sawyers; Irving L Weissman
Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML.
The New England journal of medicine 2004;351(7):657-67.
2004: S Kelly; Tonya M Bliss; Aashit K Shah; G H Sun; M Ma; W C Foo; Joanna Masel; M A Yenari; Irving L Weissman; Nobuko Uchida; Theo D Palmer; Gary K Steinberg
Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat cerebral cortex.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(32):11839-44.
2004: Armin Baiker; Konstanze Fabel; Antonio Cozzio; Leigh Zerboni; Konstanze Fabel; Marvin Sommer; Nobuko Uchida; Dongping He; Irving L Weissman; Ann M Arvin
Varicella-zoster virus infection of human neural cells in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(29):10792-7.
2004: Miriam Merad; Petra Hoffmann; Erik Ranheim; Sarah Slaymaker; Markus G Manz; sergio lira; Israel F Charo; Donald N Cook; Irving L Weissman; Samuel Strober; Edgar G Engleman
Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease.
Nature medicine 2004;10(5):510-7.
2004: Chi Wai So; Holger Karsunky; Piu Wong; Irving L Weissman; Michael L Cleary
Leukemic transformation of hematopoietic progenitors by MLL-GAS7 in the absence of Hoxa7 or Hoxa9.
Blood 2004;103(8):3192-9.
2004: Leora B Balsam; Amy J Wagers; Julie L Christensen; Theo Kofidis; Irving L Weissman; Robert C Robbins
Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium.
Nature 2004;428(6983):668-73.
2004: Amy J Wagers; Irving L Weissman
Plasticity of adult stem cells.
Cell 2004;116(5):639-48.
2004: Julie L Christensen; Douglas E Wright; Amy J Wagers; Irving L Weissman
Circulation and chemotaxis of fetal hematopoietic stem cells.
PLoS biology 2004;2(3):E75.
2004: Anthony W de Tomaso; Irving L Weissman
Evolution of a protochordate allorecognition locus.
Science (New York, N.Y.) 2004;303(5660):977.
2004: Muhammad Al-Hajj; Michael W Becker; Max S Wicha; Irving L Weissman; Michael F Clarke
Therapeutic implications of cancer stem cells.
Current opinion in genetics & development 2004;14(1):43-7.
2004: Yu-An Cao; Amy J Wagers; Andreas Beilhack; Joan Dusich; Michael H Bachmann; Robert S Negrin; Irving L Weissman; Christopher H Contag
Shifting foci of hematopoiesis during reconstitution from single stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(1):221-6.
2004: Richard I Sherwood; Julie L Christensen; Irving L Weissman; Amy J Wagers
Determinants of skeletal muscle contributions from circulating cells, bone marrow cells, and hematopoietic stem cells.
Stem cells (Dayton, Ohio) 2004;22(7):1292-304.
2004: Theo Kofidis; Jorg L de Bruin; Toshiyuki Yamane; Leora B Balsam; Darren R Lebl; Rutger-Jan Swijnenburg; Masashi Tanaka; Irving L Weissman; Robert C Robbins
Insulin-like growth factor promotes engraftment, differentiation, and functional improvement after transfer of embryonic stem cells for myocardial restoration.
Stem cells (Dayton, Ohio) 2004;22(7):1239-45.
2003: Antonio Cozzio; Emmanuelle Passegué; Paul M Ayton; Holger Karsunky; Michael L Cleary; Irving L Weissman
Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors.
Genes & development 2003;17(24):3029-35.
2003: Mathew C Easterday; Joseph D Dougherty; Robert L Jackson; Jing Ou; Ichiro Nakano; Andres A Paucar; Babak Roobini; Mehrnoosh Dianati; Dwain K Irvin; Irving L Weissman; Alexey V Terskikh; Daniel Geschwind; Harley I Kornblum
Neural progenitor genes. Germinal zone expression and analysis of genetic overlap in stem cell populations.
Developmental biology 2003;264(2):309-22.
2003: Anthony W de Tomaso; Irving L Weissman
Initial characterization of a protochordate histocompatibility locus.
Immunogenetics 2003;55(7):480-90.
2003: Emmanuelle Passegué; Catriona H M Jamieson; Laurie Ailles; Irving L Weissman
Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?
Proceedings of the National Academy of Sciences of the United States of America 2003;100 Suppl 1():11842-9.
2003: Siddhartha Jaiswal; David Traver; Toshihiro Miyamoto; Koichi Akashi; Eric Lagasse; Irving L Weissman
Expression of BCR/ABL and BCL-2 in myeloid progenitors leads to myeloid leukemias.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(17):10002-7.
2003: Devavani Chatterjea-Matthes; Marcos E García-Ojeda; Sussan Dejbakhsh-Jones; Libuse Jerabek; Markus G Manz; Irving L Weissman; Samuel Strober
Early defect prethymic in bone marrow T cell progenitors in athymic nu/nu mice.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(3):1207-15.
2003: Holger Karsunky; Miriam Merad; Antonio Cozzio; Irving L Weissman; Markus G Manz
Flt3 ligand regulates dendritic cell development from Flt3+ lymphoid and myeloid-committed progenitors to Flt3+ dendritic cells in vivo.
The Journal of experimental medicine 2003;198(2):305-13.
2003: Rich Allsopp; Gregg B Morin; Ronald A DePinho; Calvin B Harley; Irving L Weissman
Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation.
Blood 2003;102(2):517-20.
2003: Caroline Arber; Andrew BitMansour; Tim E. Sparer; John P Higgins; Edward Mocarski; Irving L Weissman; Judith A Shizuru; Janice M Y Brown
Common lymphoid progenitors rapidly engraft and protect against lethal murine cytomegalovirus infection after hematopoietic stem cell transplantation.
Blood 2003;102(2):421-8.
2003: Jos Domen; Irving L Weissman
Hematopoietic stem cells and other hematopoietic cells show broad resistance to chemotherapeutic agents in vivo when overexpressing bcl-2.
Experimental hematology 2003;31(7):631-9.
2003: Alexey V Terskikh; Toshihiro Miyamoto; Cynthia Chang; Luda Diatchenko; Irving L Weissman
Gene expression analysis of purified hematopoietic stem cells and committed progenitors.
Blood 2003;102(1):94-101.
2003: Karl Willert; Jeffrey D Brown; Esther Danenberg; Andrew W Duncan; Irving L Weissman; Tannishtha Reya; John R Yates; Roel Nusse
Wnt proteins are lipid-modified and can act as stem cell growth factors.
Nature 2003;423(6938):448-52.
2003: Tannishtha Reya; Andrew W Duncan; Laurie Ailles; Jos Domen; David C Scherer; Karl Willert; Lindsay Hintz; Roel Nusse; Irving L Weissman
A role for Wnt signalling in self-renewal of haematopoietic stem cells.
Nature 2003;423(6938):409-14.
2003: In-Kyung Park; Dalong Qian; Mark J Kiel; Michael W Becker; Michael Pihalja; Irving L Weissman; Sean J Morrison; Michael F Clarke
Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells.
Nature 2003;423(6937):302-5.
2003: Rich Allsopp; Gregg B Morin; James W Horner; Ronald A DePinho; Calvin B Harley; Irving L Weissman
Effect of TERT over-expression on the long-term transplantation capacity of hematopoietic stem cells.
Nature medicine 2003;9(4):369-71.
2003: Anthony W de Tomaso; Irving L Weissman
Construction and characterization of large-insert genomic libraries (BAC and fosmid) from the Ascidian Botryllus schlosseri and initial physical mapping of a histocompatibility locus.
Marine biotechnology (New York, N.Y.) 2003;5(2):103-15.
2003: Chi Wai So; Holger Karsunky; Emmanuelle Passegué; Antonio Cozzio; Irving L Weissman; Michael L Cleary
MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in mice.
Cancer cell 2003;3(2):161-71.
2003: Thanyaphong Na Nakorn; Toshihiro Miyamoto; Irving L Weissman
Characterization of mouse clonogenic megakaryocyte progenitors.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(1):205-10.
2003: Motonari Kondo; Amy J Wagers; Markus G Manz; Prohaska Susan; David C Scherer; Georg F Beilhack; Judith A Shizuru; Irving L Weissman
Biology of hematopoietic stem cells and progenitors: implications for clinical application.
Annual review of immunology 2003;21():759-806.
2003: Georg F Beilhack; Yolanda C Scheffold; Irving L Weissman; Cariel Taylor; Libuse Jerabek; Matthew J Burge; Marilyn A Masek; Judith A Shizuru
Purified allogeneic hematopoietic stem cell transplantation blocks diabetes pathogenesis in NOD mice.
Diabetes 2003;52(1):59-68.
2002: Andrew BitMansour; Stacy M Burns; David Traver; Koichi Akashi; Christopher H Contag; Irving L Weissman; Janice M Y Brown
Myeloid progenitors protect against invasive aspergillosis and Pseudomonas aeruginosa infection following hematopoietic stem cell transplantation.
Blood 2002;100(13):4660-7.
2002: Rich Allsopp; Samuel Cheshier; Irving L Weissman
Telomerase activation and rejuvenation of telomere length in stimulated T cells derived from serially transplanted hematopoietic stem cells.
The Journal of experimental medicine 2002;196(11):1427-33.
2002: Prohaska Susan; David C Scherer; Irving L Weissman; Motonari Kondo
Developmental plasticity of lymphoid progenitors.
Seminars in immunology 2002;14(6):377-84.
2002: Miriam Merad; Markus G Manz; Holger Karsunky; Amy J Wagers; Wendy Peters; Israel F Charo; Irving L Weissman; Jason G Cyster; Edgar G Engleman
Langerhans cells renew in the skin throughout life under steady-state conditions.
Nature immunology 2002;3(12):1135-41.
2002: Amy J Wagers; Richard I Sherwood; Julie L Christensen; Irving L Weissman
Little evidence for developmental plasticity of adult hematopoietic stem cells.
Science (New York, N.Y.) 2002;297(5590):2256-9.
2002: Markus G Manz; Toshihiro Miyamoto; Koichi Akashi; Irving L Weissman
Prospective isolation of human clonogenic common myeloid progenitors.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(18):11872-7.
2002: Irving L Weissman
The road ended up at stem cells.
Immunological reviews 2002;185():159-74.
2002: Toshihiro Miyamoto; Hiromi Iwasaki; Boris Reizis; Min Ye; Thomas Graf; Irving L Weissman; Koichi Akashi
Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment.
Developmental cell 2002;3(1):137-47.
2002: Thanyaphong Na Nakorn; David Traver; Irving L Weissman; Koichi Akashi
Myeloerythroid-restricted progenitors are sufficient to confer radioprotection and provide the majority of day 8 CFU-S.
The Journal of clinical investigation 2002;109(12):1579-85.
2002: Irving L Weissman
Stem cells--scientific, medical, and political issues.
The New England journal of medicine 2002;346(20):1576-9.
2002: Rich Allsopp; Irving L Weissman
Replicative senescence of hematopoietic stem cells during serial transplantation: does telomere shortening play a role?
Oncogene 2002;21(21):3270-3.
2002: Douglas E Wright; Edward P Bowman; Amy J Wagers; Eugene C Butcher; Irving L Weissman
Hematopoietic stem cells are uniquely selective in their migratory response to chemokines.
The Journal of experimental medicine 2002;195(9):1145-54.
2002: Amy J Wagers; Julie L Christensen; Irving L Weissman
Cell fate determination from stem cells.
Gene therapy 2002;9(10):606-12.
2002: Angela G King; Motonari Kondo; David C Scherer; Irving L Weissman
Lineage infidelity in myeloid cells with TCR gene rearrangement: a latent developmental potential of proT cells revealed by ectopic cytokine receptor signaling.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(7):4508-13.
2002: Amy J Wagers; Rich Allsopp; Irving L Weissman
Changes in integrin expression are associated with altered homing properties of Lin(-/lo)Thy1.1(lo)Sca-1(+)c-kit(+) hematopoietic stem cells following mobilization by cyclophosphamide/granulocyte colony-stimulating factor.
Experimental hematology 2002;30(2):176-85.
2002: In-Kyung Park; Yaqin He; Fangming Lin; Ole D Laerum; Qiang Tian; Roger Bumgarner; Christopher A Klug; Kaijun Li; Christian Kuhr; Michelle J Doyle; Tao Xie; Michèl Schummer; Yu Sun; Adam Marc Goldsmith; Michael F Clarke; Irving L Weissman; Leroy Hood; Linheng Li
Differential gene expression profiling of adult murine hematopoietic stem cells.
Blood 2002;99(2):488-98.
2002: Sean J Morrison; Dalong Qian; Libuse Jerabek; Bonnie A Thiel; In-Kyung Park; Preston S Ford; Mark J Kiel; Nicholas J Schork; Irving L Weissman; Michael F Clarke
A genetic determinant that specifically regulates the frequency of hematopoietic stem cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(2):635-42.
2002: Libuse Jerabek; Irving L Weissman
Intrathymic injection for analysis of T-cell progenitor activity.
Methods in molecular medicine 2002;63():161-5.
2001: Julie L Christensen; Irving L Weissman
Flk-2 is a marker in hematopoietic stem cell differentiation: a simple method to isolate long-term stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(25):14541-6.
2001: Douglas E Wright; Amy J Wagers; A P Gulati; Frances L Johnson; Irving L Weissman
Physiological migration of hematopoietic stem and progenitor cells.
Science (New York, N.Y.) 2001;294(5548):1933-6.
2001: Tannishtha Reya; Sean J Morrison; Michael F Clarke; Irving L Weissman
Stem cells, cancer, and cancer stem cells.
Nature 2001;414(6859):105-11.
2001: Motonari Kondo; David C Scherer; Angela G King; M G Manz; Irving L Weissman
Lymphocyte development from hematopoietic stem cells.
Current opinion in genetics & development 2001;11(5):520-6.
2001: David Traver; Toshihiro Miyamoto; J Christensen; J Iwasaki-Arai; Koichi Akashi; Irving L Weissman
Fetal liver myelopoiesis occurs through distinct, prospectively isolatable progenitor subsets.
Blood 2001;98(3):627-35.
2001: Jorge F DiMartino; Licia Selleri; David Traver; M T Firpo; J Rhee; Roger A Warnke; S O'Gorman; Irving L Weissman; Michael L Cleary
The Hox cofactor and proto-oncogene Pbx1 is required for maintenance of definitive hematopoiesis in the fetal liver.
Blood 2001;98(3):618-26.
2001: Alexey V Terskikh; Mathew C Easterday; Li Li; L Hood; Harley I Kornblum; Daniel Geschwind; Irving L Weissman
From hematopoiesis to neuropoiesis: evidence of overlapping genetic programs.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(14):7934-9.
2001: Markus G Manz; David Traver; Koichi Akashi; Miriam Merad; Toshihiro Miyamoto; Edgar G Engleman; Irving L Weissman
Dendritic cell development from common myeloid progenitors.
Annals of the New York Academy of Sciences 2001;938():167-73; discussion 173-4.
2001: Markus G Manz; David Traver; Toshihiro Miyamoto; Irving L Weissman; Koichi Akashi
Dendritic cell potentials of early lymphoid and myeloid progenitors.
Blood 2001;97(11):3333-41.
2001: Reina E Mebius; T Miyamoto; J Christensen; J Domen; Tom Cupedo; Irving L Weissman; Koichi Akashi
The fetal liver counterpart of adult common lymphoid progenitors gives rise to all lymphoid lineages, CD45+CD4+CD3- cells, as well as macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(11):6593-601.
2001: Rich Allsopp; Samuel Cheshier; Irving L Weissman
Telomere shortening accompanies increased cell cycle activity during serial transplantation of hematopoietic stem cells.
The Journal of experimental medicine 2001;193(8):917-24.
2001: Douglas E Wright; Samuel Cheshier; Amy J Wagers; T D Randall; Julie L Christensen; Irving L Weissman
Cyclophosphamide/granulocyte colony-stimulating factor causes selective mobilization of bone marrow hematopoietic stem cells into the blood after M phase of the cell cycle.
Blood 2001;97(8):2278-85.
2001: D J Anderson; F H Gage; Irving L Weissman
Can stem cells cross lineage boundaries?
Nature medicine 2001;7(4):393-5.
2001: F Qian; Douglas Hanahan; Irving L Weissman
L-selectin can facilitate metastasis to lymph nodes in a transgenic mouse model of carcinogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(7):3976-81.
2001: Daniel Geschwind; Jing Ou; Mathew C Easterday; Joseph D Dougherty; R L Jackson; Z Chen; H Antoine; Alexey V Terskikh; Irving L Weissman; Stanley F Nelson; Harley I Kornblum
A genetic analysis of neural progenitor differentiation.
Neuron 2001;29(2):325-39.
2000: J Domen; Irving L Weissman
Hematopoietic stem cells need two signals to prevent apoptosis; BCL-2 can provide one of these, Kitl/c-Kit signaling the other.
The Journal of experimental medicine 2000;192(12):1707-18.
2000: David Traver; Koichi Akashi; Markus G Manz; Miriam Merad; Toshihiro Miyamoto; Edgar G Engleman; Irving L Weissman
Development of CD8alpha-positive dendritic cells from a common myeloid progenitor.
Science (New York, N.Y.) 2000;290(5499):2152-4.
2000: Alexey V Terskikh; Arkady F Fradkov; Galina V Ermakova; Andrey G Zaraisky; P Tan; Andrey V Kajava; X Zhao; S Lukyanov; Mikhail V Matz; S Kim; Irving L Weissman; Paul D Siebert
"Fluorescent timer": protein that changes color with time.
Science (New York, N.Y.) 2000;290(5496):1585-8.
2000: Motonari Kondo; David C Scherer; Toshihiro Miyamoto; Angela G King; Koichi Akashi; K Sugamura; Irving L Weissman
Cell-fate conversion of lymphoid-committed progenitors by instructive actions of cytokines.
Nature 2000;407(6802):383-6.
2000: Judith A Shizuru; Irving L Weissman; RS Kernoff; Marilyn A Masek; Yolanda C Scheffold
Purified hematopoietic stem cell grafts induce tolerance to alloantigens and can mediate positive and negative T cell selection.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(17):9555-60.
2000: C A Klug; Samuel Cheshier; Irving L Weissman
Inactivation of a GFP retrovirus occurs at multiple levels in long-term repopulating stem cells and their differentiated progeny.
Blood 2000;96(3):894-901.
2000: Toshihiro Miyamoto; Irving L Weissman; Koichi Akashi
AML1/ETO-expressing nonleukemic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocation.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(13):7521-6.
2000: D J Laird; Anthony W de Tomaso; Max D Cooper; Irving L Weissman
50 million years of chordate evolution: seeking the origins of adaptive immunity.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(13):6924-6.
2000: Koichi Akashi; L I Richie; T Miyamoto; William Henry Carr; Irving L Weissman
B lymphopoiesis in the thymus.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(10):5221-6.
2000: Koichi Akashi; Tannishtha Reya; Dennise Dalma-Weiszhausz; Irving L Weissman
Lymphoid precursors.
Current opinion in immunology 2000;12(2):144-50.
2000: Koichi Akashi; David Traver; Toshihiro Miyamoto; Irving L Weissman
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages.
Nature 2000;404(6774):193-7.
2000: Irving L Weissman
Translating stem and progenitor cell biology to the clinic: barriers and opportunities.
Science (New York, N.Y.) 2000;287(5457):1442-6.
2000: J Domen; Samuel Cheshier; Irving L Weissman
The role of apoptosis in the regulation of hematopoietic stem cells: Overexpression of Bcl-2 increases both their number and repopulation potential.
The Journal of experimental medicine 2000;191(2):253-64.
2000: Irving L Weissman
Stem cells: units of development, units of regeneration, and units in evolution.
Cell 2000;100(1):157-68.
2000: Motonari Kondo; Irving L Weissman
Function of cytokines in lymphocyte development.
Current topics in microbiology and immunology 2000;251():59-65.
2000: Robert S Negrin; K Atkinson; Thomas Leemhuis; EG Hanania; C Juttner; K Tierney; Wendy W Hu; Laura J Johnston; J A Shizurn; Keith E Stockerl-Goldstein; Karl G Blume; Irving L Weissman; S Bower; RD Baynes; Roger Dansey; Chatchada Karanes; W Peters; J Klein
Transplantation of highly purified CD34+Thy-1+ hematopoietic stem cells in patients with metastatic breast cancer.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2000;6(3):262-71.
1999: Kimberly L Gandy; J Domen; H Aguila; Irving L Weissman
CD8+TCR+ and CD8+TCR- cells in whole bone marrow facilitate the engraftment of hematopoietic stem cells across allogeneic barriers.
Immunity 1999;11(5):579-90.
1999: DS Stoner; B Rinkevich; Irving L Weissman
Heritable germ and somatic cell lineage competitions in chimeric colonial protochordates.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(16):9148-53.
1999: Koichi Akashi; David Traver; Motonari Kondo; Irving L Weissman
Lymphoid development from hematopoietic stem cells.
International journal of hematology 1999;69(4):217-26.
1999: J Domen; Irving L Weissman
Self-renewal, differentiation or death: regulation and manipulation of hematopoietic stem cell fate.
Molecular medicine today 1999;5(5):201-8.
1999: Samuel Cheshier; Sean J Morrison; X Liao; Irving L Weissman
In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):3120-5.
1999: M Trahey; Irving L Weissman
Cyclophilin C-associated protein: a normal secreted glycoprotein that down-modulates endotoxin and proinflammatory responses in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):3006-11.
1999: BG Magor; Anthony W de Tomaso; B Rinkevich; Irving L Weissman
Allorecognition in colonial tunicates: protection against predatory cell lineages?
Immunological reviews 1999;167():69-79.
1999: Koichi Akashi; Motonari Kondo; Samuel Cheshier; Judith A Shizuru; Kimberly L Gandy; J Domen; Reina E Mebius; David Traver; Irving L Weissman
Lymphoid development from stem cells and the common lymphocyte progenitors.
Cold Spring Harbor symposia on quantitative biology 1999;64():1-12.
1998: Reina E Mebius; S van Tuijl; Irving L Weissman; T D Randall
Transfer of primitive stem/progenitor bone marrow cells from LT alpha-/- donors to wild-type hosts: implications for the generation of architectural events in lymphoid B cell domains.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(8):3836-43.
1998: Baruch Rinkevich; Irving L Weissman; Anthony W de Tomaso
Transplantation of Fu/HC-incompatible zooids in Botryllus schlosseri results in chimerism.
The Biological bulletin 1998;195(2):98-106.
1998: MB Fagan; Irving L Weissman
Characterization of a polymorphic protein localized to vascular epithelium in Botryllus schlosseri: role in tunic synthesis?
Molecular marine biology and biotechnology 1998;7(3):204-13.
1998: David Traver; Koichi Akashi; Irving L Weissman; Eric Lagasse
Mice defective in two apoptosis pathways in the myeloid lineage develop acute myeloblastic leukemia.
Immunity 1998;9(1):47-57.
1998: Marcos E García-Ojeda; Sussan Dejbakhsh-Jones; Irving L Weissman; Samuel Strober
An alternate pathway for T cell development supported by the bone marrow microenvironment: recapitulation of thymic maturation.
The Journal of experimental medicine 1998;187(11):1813-23.
1998: Anthony W de Tomaso; Y Saito; Katherine J Ishizuka; K J Palmeri; Irving L Weissman
Mapping the genome of a model protochordate. I. A low resolution genetic map encompassing the fusion/histocompatibility (Fu/HC) locus of Botryllus schlosseri.
Genetics 1998;149(1):277-87.
1998: MB Fagan; Irving L Weissman
Linkage analysis of HSP70 genes and historecognition locus in botryllus schlosseri.
Immunogenetics 1998;47(6):468-76.
1998: J Domen; Kimberly L Gandy; Irving L Weissman
Systemic overexpression of BCL-2 in the hematopoietic system protects transgenic mice from the consequences of lethal irradiation.
Blood 1998;91(7):2272-82.
1998: K Hahm; Bradley S Cobb; Aaron S McCarty; Karen E Brown; CA Klug; R Lee; Koichi Akashi; Irving L Weissman; Amanda G Fisher; Stephen T Smale
Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatin.
Genes & development 1998;12(6):782-96.
1998: Koichi Akashi; Motonari Kondo; Irving L Weissman
Two distinct pathways of positive selection for thymocytes.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(5):2486-91.
1998: Kimberly L Gandy; Irving L Weissman
Tolerance of allogeneic heart grafts in mice simultaneously reconstituted with purified allogeneic hematopoietic stem cells.
Transplantation 1998;65(3):295-304.
1998: CA Klug; Sean J Morrison; Marilyn A Masek; K Hahm; Stephen T Smale; Irving L Weissman
Hematopoietic stem cells and lymphoid progenitors express different Ikaros isoforms, and Ikaros is localized to heterochromatin in immature lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(2):657-62.
1998: Reina E Mebius; Inge L Schadee-Eestermans; Irving L Weissman
MAdCAM-1 dependent colonization of developing lymph nodes involves a unique subset of CD4+CD3- hematolymphoid cells.
Cell adhesion and communication 1998;6(2-3):97-103.
1998: T D Randall; Irving L Weissman
Characterization of a population of cells in the bone marrow that phenotypically mimics hematopoietic stem cells: resting stem cells or mystery population?
Stem cells (Dayton, Ohio) 1998;16(1):38-48.
1997: Motonari Kondo; Irving L Weissman; Koichi Akashi
Identification of clonogenic common lymphoid progenitors in mouse bone marrow.
Cell 1997;91(5):661-72.
1997: Reina E Mebius; P Rennert; Irving L Weissman
Developing lymph nodes collect CD4+CD3- LTbeta+ cells that can differentiate to APC, NK cells, and follicular cells but not T or B cells.
Immunity 1997;7(4):493-504.
1997: DS Stoner; Joseph M Quattro; Irving L Weissman
Highly polymorphic microsatellite loci in the colonial ascidian Botryllus schlosseri.
Molecular marine biology and biotechnology 1997;6(3):163-71.
1997: Motonari Kondo; Koichi Akashi; J Domen; K Sugamura; Irving L Weissman
Bcl-2 rescues T lymphopoiesis, but not B or NK cell development, in common gamma chain-deficient mice.
Immunity 1997;7(1):155-62.
1997: Koichi Akashi; Motonari Kondo; U von Freeden-Jeffry; R Murray; Irving L Weissman
Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice.
Cell 1997;89(7):1033-41.
1997: Eric Lagasse; Irving L Weissman
Enforced expression of Bcl-2 in monocytes rescues macrophages and partially reverses osteopetrosis in op/op mice.
Cell 1997;89(7):1021-31.
1997: H L Aguila; Koichi Akashi; J Domen; Kimberly L Gandy; Eric Lagasse; Reina E Mebius; Sean J Morrison; Judith A Shizuru; Samuel Strober; N Uchida; DE Wright; Irving L Weissman
From stem cells to lymphocytes: biology and transplantation.
Immunological reviews 1997;157():13-40.
1997: Sean J Morrison; A M Wandycz; H D Hemmati; DE Wright; Irving L Weissman
Identification of a lineage of multipotent hematopoietic progenitors.
Development (Cambridge, England) 1997;124(10):1929-39.
1997: Sean J Morrison; D E Wright; Samuel Cheshier; Irving L Weissman
Hematopoietic stem cells: challenges to expectations.
Current opinion in immunology 1997;9(2):216-21.
1997: Sean J Morrison; DE Wright; Irving L Weissman
Cyclophosphamide/granulocyte colony-stimulating factor induces hematopoietic stem cells to proliferate prior to mobilization.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(5):1908-13.
1997: MB Fagan; Irving L Weissman
HSP70 genes and historecognition in Botryllus schlosseri: implications for MHC evolution.
Hereditas 1997;127(1-2):25-35.
1996: D S Stoner; Irving L Weissman
Somatic and germ cell parasitism in a colonial ascidian: possible role for a highly polymorphic allorecognition system.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(26):15254-9.
1996: Eric Lagasse; Irving L Weissman
Flow cytometric identification of murine neutrophils and monocytes.
Journal of immunological methods 1996;197(1-2):139-50.
1996: G F Tidmarsh; S Heimfeld; C A Whitlock; Irving L Weissman; C E Müller-Sieburg
Identification of a novel bone marrow-derived B-cell progenitor population that coexpresses B220 and Thy-1 and is highly enriched for Abelson leukemia virus targets.
Molecular and cellular biology 1996;16(10):5946.
1996: Reina E Mebius; Philip R Streeter; Sara A Michie; Eugene C Butcher; Irving L Weissman
A developmental switch in lymphocyte homing receptor and endothelial vascular addressin expression regulates lymphocyte homing and permits CD4+ CD3- cells to colonize lymph nodes.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(20):11019-24.
1996: Sean J Morrison; K R Prowse; P Ho; Irving L Weissman
Telomerase activity in hematopoietic cells is associated with self-renewal potential.
Immunity 1996;5(3):207-16.
1996: Sean J Morrison; A M Wandycz; Koichi Akashi; A Globerson; Irving L Weissman
The aging of hematopoietic stem cells.
Nature medicine 1996;2(9):1011-6.
1996: Koichi Akashi; Irving L Weissman
The c-kit+ maturation pathway in mouse thymic T cell development: lineages and selection.
Immunity 1996;5(2):147-61.
1996: N Uchida; L Jerabek; Irving L Weissman
Searching for hematopoietic stem cells. II. The heterogeneity of Thy-1.1(lo)Lin(-/lo)Sca-1+ mouse hematopoietic stem cells separated by counterflow centrifugal elutriation.
Experimental hematology 1996;24(5):649-59.
1996: Irving L Weissman
From thymic lineages back to hematopoietic stem cells, sometimes using homing receptors.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(6):2019-25.
1996: H L Aguila; Irving L Weissman
Hematopoietic stem cells are not direct cytotoxic targets of natural killer cells.
Blood 1996;87(4):1225-31.
1996: Judith A Shizuru; L Jerabek; C T Edwards; Irving L Weissman
Transplantation of purified hematopoietic stem cells: requirements for overcoming the barriers of allogeneic engraftment.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 1996;2(1):3-14.
1996: M B Fagan; Irving L Weissman
Sequence and characterization of two HSP70 genes in the colonial protochordate Botryllus schlosseri.
Immunogenetics 1996;44(2):134-42.
1995: B A Mehta; Ingo G H Schmidt-Wolf; Irving L Weissman; Robert S Negrin
Two pathways of exocytosis of cytoplasmic granule contents and target cell killing by cytokine-induced CD3+ CD56+ killer cells.
Blood 1995;86(9):3493-9.
1995: Sean J Morrison; H D Hemmati; A M Wandycz; Irving L Weissman
The purification and characterization of fetal liver hematopoietic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(22):10302-6.
1995: H L Aguila; R J Hershberger; Irving L Weissman
Transgenic mice carrying the diphtheria toxin A chain gene under the control of the granzyme A promoter: expected depletion of cytotoxic cells and unexpected depletion of CD8 T cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(22):10192-6.
1995: Sussan Dejbakhsh-Jones; L Jerabek; Irving L Weissman; Samuel Strober
Extrathymic maturation of alpha beta T cells from hemopoietic stem cells.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(7):3338-44.
1995: Sean J Morrison; Irving L Weissman
Heterogeneity of hematopoietic stem cells: implications for clinical applications.
Proceedings of the Association of American Physicians 1995;107(2):187-94.
1995: Sean J Morrison; N Uchida; Irving L Weissman
The biology of hematopoietic stem cells.
Annual review of cell and developmental biology 1995;11():35-71.
1994: Sean J Morrison; Irving L Weissman
The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype.
Immunity 1994;1(8):661-73.
1994: Irving L Weissman
Stem cells, clonal progenitors, and commitment to the three lymphocyte lineages: T, B, and NK cells.
Immunity 1994;1(7):529-31.
1994: A Sen-Majumdar; Cynthia J Guidos; T Kina; M Lieberman; Irving L Weissman
Characterization of preneoplastic thymocytes and of their neoplastic progression in irradiated C57BL/Ka mice.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(4):1581-92.
1994: N Uchida; H L Aguila; William H Fleming; L Jerabek; Irving L Weissman
Rapid and sustained hematopoietic recovery in lethally irradiated mice transplanted with purified Thy-1.1lo Lin-Sca-1+ hematopoietic stem cells.
Blood 1994;83(12):3758-79.
1994: Sean J Morrison; Eric Lagasse; Irving L Weissman
Demonstration that Thy(lo) subsets of mouse bone marrow that express high levels of lineage markers are not significant hematopoietic progenitors.
Blood 1994;83(12):3480-90.
1994: J Friedman; Irving L Weissman; J Friedman; S Alpert
An analysis of the expression of cyclophilin C reveals tissue restriction and an intriguing pattern in the mouse kidney.
The American journal of pathology 1994;144(6):1247-56.
1994: D T Crowe; H Chiu; S Fong; Irving L Weissman
Regulation of the avidity of integrin alpha 4 beta 7 by the beta 7 cytoplasmic domain.
The Journal of biological chemistry 1994;269(20):14411-8.
1994: F Qian; D L Vaux; Irving L Weissman
Expression of the integrin alpha 4 beta 1 on melanoma cells can inhibit the invasive stage of metastasis formation.
Cell 1994;77(3):335-47.
1994: S Bartl; Irving L Weissman
The isolation of putative major histocompatibility complex gene fragments from dogfish and nurse shark.
Annals of the New York Academy of Sciences 1994;712():346-9.
1994: Bruno Péault; Ibrahim Khazaal; Irving L Weissman
In vitro development of B cells and macrophages from early mouse fetal thymocytes.
European journal of immunology 1994;24(3):781-4.
1994: Eric Lagasse; Irving L Weissman
bcl-2 inhibits apoptosis of neutrophils but not their engulfment by macrophages.
The Journal of experimental medicine 1994;179(3):1047-52.
1994: A Sen-Majumdar; Irving L Weissman; G Hansteen; J Marian; Edmond WALLER; M Lieberman
Radiation leukemia virus-induced thymic lymphomas express a restricted repertoire of T-cell receptor V beta gene products.
Journal of virology 1994;68(2):1165-72.
1994: Irving L Weissman
Developmental switches in the immune system.
Cell 1994;76(2):207-18.
1994: S Bartl; Irving L Weissman
Isolation and characterization of major histocompatibility complex class IIB genes from the nurse shark.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(1):262-6.
1993: Ingo G H Schmidt-Wolf; P Lefterova; B A Mehta; L P Fernandez; Dieter Huhn; Karl G Blume; Irving L Weissman; Robert S Negrin
Phenotypic characterization and identification of effector cells involved in tumor cell recognition of cytokine-induced killer cells.
Experimental hematology 1993;21(13):1673-9.
1993: D L Vaux; Irving L Weissman
Neither macromolecular synthesis nor myc is required for cell death via the mechanism that can be controlled by Bcl-2.
Molecular and cellular biology 1993;13(11):7000-5.
1993: Irving L Weissman; Max D Cooper
How the immune system develops.
Scientific American 1993;269(3):64-71.
1993: William H Fleming; E J Alpern; N Uchida; K Ikuta; G J Spangrude; Irving L Weissman
Functional heterogeneity is associated with the cell cycle status of murine hematopoietic stem cells.
The Journal of cell biology 1993;122(4):897-902.
1993: C Berlin; Ellen L Berg; Michael Briskin; David Andrew; P J Kilshaw; Bernhard Holzmann; Irving L Weissman; A Hamann; Eugene C Butcher
Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1.
Cell 1993;74(1):185-95.
1993: J Friedman; M Trahey; Irving L Weissman
Cloning and characterization of cyclophilin C-associated protein: a candidate natural cellular ligand for cyclophilin C.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(14):6815-9.
1993: D L Kraft; Irving L Weissman; Edmond WALLER
Differentiation of CD3-4-8- human fetal thymocytes in vivo: characterization of a CD3-4+8- intermediate.
The Journal of experimental medicine 1993;178(1):265-77.
1993: Edmond WALLER; M Ziemianska; C D Bangs; M Cleary; Irving L Weissman; Onsi W Kamel
Characterization of posttransplant lymphomas that express T-cell-associated markers: immunophenotypes, molecular genetics, cytogenetics, and heterotransplantation in severe combined immunodeficient mice.
Blood 1993;82(1):247-61.
1993: L Su; R J Hershberger; Irving L Weissman
LYAR, a novel nucleolar protein with zinc finger DNA-binding motifs, is involved in cell growth regulation.
Genes & development 1993;7(5):735-48.
1993: William H Fleming; E J Alpern; N Uchida; K Ikuta; Irving L Weissman
Steel factor influences the distribution and activity of murine hematopoietic stem cells in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3760-4.
1993: N Uchida; William H Fleming; E J Alpern; Irving L Weissman
Heterogeneity of hematopoietic stem cells.
Current opinion in immunology 1993;5(2):177-84.
1993: R H Chen; K W Ivens; S Alpert; Margaret E Billingham; C Garrison Fathman; T F Flavin; Judith A Shizuru; Vaughn A Starnes; Irving L Weissman; G M Griffiths
The use of granzyme A as a marker of heart transplant rejection in cyclosporine or anti-CD4 monoclonal antibody-treated rats.
Transplantation 1993;55(1):146-53.
1993: M C Hu; Bernhard Holzmann; D T Crowe; H Neuhaus; Irving L Weissman
The Peyer's patch homing receptor.
Current topics in microbiology and immunology 1993;184():125-38.
1992: D L Vaux; Irving L Weissman; Stuart K Kim
Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2.
Science (New York, N.Y.) 1992;258(5090):1955-7.
1992: Edmond WALLER; A Sen-Majumdar; Onsi W Kamel; G A Hansteen; M R Schick; Irving L Weissman
Human T-cell development in SCID-hu mice: staphylococcal enterotoxins induce specific clonal deletions, proliferation, and anergy.
Blood 1992;80(12):3144-56.
1992: R J Hershberger; H K Gershenfeld; Irving L Weissman; L Su
Genomic organization of the mouse granzyme A gene. Two mRNAs encode the same mature granzyme A with different leader peptides.
The Journal of biological chemistry 1992;267(35):25488-93.
1992: M C Hu; D T Crowe; Irving L Weissman; Bernhard Holzmann
Cloning and expression of mouse integrin beta p(beta 7): a functional role in Peyer's patch-specific lymphocyte homing.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(17):8254-8.
1992: M Lieberman; G A Hansteen; Edmond WALLER; Irving L Weissman; A Sen-Majumdar
Unexpected effects of the severe combined immunodeficiency mutation on murine lymphomagenesis.
The Journal of experimental medicine 1992;176(2):399-405.
1992: D L Vaux; H L Aguila; Irving L Weissman
Bcl-2 prevents death of factor-deprived cells but fails to prevent apoptosis in targets of cell mediated killing.
International immunology 1992;4(7):821-4.
1992: K Ikuta; T Kina; I MacNeil; N Uchida; B Peault; Yueh-hsiu Chien; Irving L Weissman
Development of gamma delta T-cell subsets from fetal hematopoietic stem cells.
Annals of the New York Academy of Sciences 1992;651():21-32.
1992: Eric Lagasse; Irving L Weissman
Mouse MRP8 and MRP14, two intracellular calcium-binding proteins associated with the development of the myeloid lineage.
Blood 1992;79(8):1907-15.
1992: K Ikuta; Irving L Weissman
Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(4):1502-6.
1992: G M Griffiths; S Alpert; E Lambert; J McGuire; Irving L Weissman
Perforin and granzyme A expression identifying cytolytic lymphocytes in rheumatoid arthritis.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(2):549-53.
1992: S Heimfeld; Irving L Weissman
Characterization of several classes of mouse hematopoietic progenitor cells.
Current topics in microbiology and immunology 1992;177():95-105.
1992: N Uchida; Irving L Weissman
Searching for hematopoietic stem cells: evidence that Thy-1.1lo Lin- Sca-1+ cells are the only stem cells in C57BL/Ka-Thy-1.1 bone marrow.
The Journal of experimental medicine 1992;175(1):175-84.
1992: M C Hu; M H Siegelman; Bernhard Holzmann; D T Crowe; Irving L Weissman
Lymphocyte homing receptors.
Cold Spring Harbor symposia on quantitative biology 1992;57():291-308.
1991: Edmond WALLER; Onsi W Kamel; Michael L Cleary; A S Majumdar; M R Schick; M Lieberman; Irving L Weissman
Growth of primary T-cell non-Hodgkin's lymphomata in SCID-hu mice: requirement for a human lymphoid microenvironment.
Blood 1991;78(10):2650-65.
1991: H Neuhaus; M C Hu; Martin Helmer; Yoshikazu Takada; Bernhard Holzmann; Irving L Weissman
Cloning and expression of cDNAs for the alpha subunit of the murine lymphocyte-Peyer's patch adhesion molecule.
The Journal of cell biology 1991;115(4):1149-58.
1991: K Ikuta; Irving L Weissman
The junctional modifications of a T cell receptor gamma chain are determined at the level of thymic precursors.
The Journal of experimental medicine 1991;174(5):1279-82.
1991: G J Spangrude; L Smith; N Uchida; K Ikuta; S Heimfeld; J Friedman; Irving L Weissman
Mouse hematopoietic stem cells.
Blood 1991;78(6):1395-402.
1991: Irving L Weissman; G Spangrude; S Heimfeld; L Smith; N Uchida
Stem cells.
Nature 1991;353(6339):26.
1991: J Friedman; Irving L Weissman
Two cytoplasmic candidates for immunophilin action are revealed by affinity for a new cyclophilin: one in the presence and one in the absence of CsA.
Cell 1991;66(4):799-806.
1991: Ingo G H Schmidt-Wolf; Robert S Negrin; H P Kiem; Karl G Blume; Irving L Weissman
Use of a SCID mouse/human lymphoma model to evaluate cytokine-induced killer cells with potent antitumor cell activity.
The Journal of experimental medicine 1991;174(1):139-49.
1991: L G Smith; Irving L Weissman; S Heimfeld
Clonal analysis of hematopoietic stem-cell differentiation in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(7):2788-92.
1991: G M Griffiths; R Namikawa; Christoph Mueller; C C Liu; J D Young; Margaret E Billingham; Irving L Weissman
Granzyme A and perforin as markers for rejection in cardiac transplantation.
European journal of immunology 1991;21(3):687-93.
1991: T Kina; A S Majumdar; S Heimfeld; H Kaneshima; Bernhard Holzmann; Y Katsura; Irving L Weissman
Identification of a 107-kD glycoprotein that mediates adhesion between stromal cells and hematolymphoid cells.
The Journal of experimental medicine 1991;173(2):373-81.
1990: K Ikuta; T Kina; I MacNeil; N Uchida; B Peault; Yueh-hsiu Chien; Irving L Weissman
A developmental switch in thymic lymphocyte maturation potential occurs at the level of hematopoietic stem cells.
Cell 1990;62(5):863-74.
1990: M van de Rijn; Irving L Weissman; M Siegelman
Biosynthesis pathway of gp90MEL-14, the mouse lymph node-specific homing receptor.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(5):1477-82.
1990: Cynthia J Guidos; Jayne S Danska; C Garrison Fathman; Irving L Weissman
T cell receptor-mediated negative selection of autoreactive T lymphocyte precursors occurs after commitment to the CD4 or CD8 lineages.
The Journal of experimental medicine 1990;172(3):835-45.
1990: M H Siegelman; I C Cheng; Irving L Weissman; E K Wakeland
The mouse lymph node homing receptor is identical with the lymphocyte cell surface marker Ly-22: role of the EGF domain in endothelial binding.
Cell 1990;61(4):611-22.
1990: M C Fariñas; Rebecca Adkins; A M Stall; Irving L Weissman; Samuel Strober
B cell infiltration of the thymic medulla in New Zealand black, New Zealand white, and (New Zealand black x New Zealand white)F1 mice. Effect of total lymphoid irradiation.
Arthritis and rheumatism 1990;33(5):702-10.
1990: Craig Y Okada; Bernhard Holzmann; Cynthia J Guidos; E Palmer; Irving L Weissman
Characterization of a rat monoclonal antibody specific for a determinant encoded by the V beta 7 gene segment. Depletion of V beta 7+ T cells in mice with Mls-1a haplotype.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(9):3473-7.
1990: Irving L Weissman; Y Saito; B Rinkevich
Allorecognition histocompatibility in a protochordate species: is the relationship to MHC somatic or structural?
Immunological reviews 1990;113():227-41.
1990: A S Majumdar; Cynthia J Guidos; H Kaneshima; J H White; J Marian; M Lieberman; Irving L Weissman
An immunodominant murine lymphoma cell surface heterodimer marks thymic progenitor subsets.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(1):111-21.
1990: Jayne S Danska; B W McIntyre; Hugh McDevitt; Irving L Weissman
Structural similarity between a primitive chordate membrane heterodimer and lymphocyte antigen receptors.
International immunology 1990;2(9):795-802.
1990: P J Sherwood; Irving L Weissman
The growth factor IL-7 induces expression of a transformation-associated antigen in normal pre-B cells.
International immunology 1990;2(5):399-406.
1989: Cynthia J Guidos; Irving L Weissman; Rebecca Adkins
Intrathymic maturation of murine T lymphocytes from CD8+ precursors.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(19):7542-6.
1989: HELEN O'NEILL; Irving L Weissman
Measurement of binding specificity between T cell lymphomas and murine leukemia viruses.
Journal of immunological methods 1989;122(1):79-90.
1989: M H Siegelman; Irving L Weissman
Human homologue of mouse lymph node homing receptor: evolutionary conservation at tandem cell interaction domains.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(14):5562-6.
1989: Cynthia J Guidos; Irving L Weissman; Rebecca Adkins
Developmental potential of CD4-8- thymocytes. Peripheral progeny include mature CD4-8- T cells bearing alpha beta T cell receptor.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(11):3773-80.
1989: Irving L Weissman; S Heimfeld; G Spangrude
Haemopoietic stem cell purification.
Immunology today 1989;10(6):184-5.
1989: Bernhard Holzmann; Irving L Weissman
Peyer's patch-specific lymphocyte homing receptors consist of a VLA-4-like alpha chain associated with either of two integrin beta chains, one of which is novel.
The EMBO journal 1989;8(6):1735-41.
1989: Matt van de Rijn; S Heimfeld; G J Spangrude; Irving L Weissman
Mouse hematopoietic stem-cell antigen Sca-1 is a member of the Ly-6 antigen family.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(12):4634-8.
1989: Cynthia J Guidos; J Ransom; M Fischer; Irving L Weissman; Albert Zlotnik
Role of interleukin-4 in T-cell ontogeny: changes in cell surface phenotype and lymphokine production of immature thymocytes after culture with interleukin-4 and phorbol ester.
Journal of autoimmunity 1989;2 Suppl():141-53.
1989: G F Tidmarsh; S Heimfeld; C A Whitlock; Irving L Weissman; C E Müller-Sieburg
Identification of a novel bone marrow-derived B-cell progenitor population that coexpresses B220 and Thy-1 and is highly enriched for Abelson leukemia virus targets.
Molecular and cellular biology 1989;9(6):2665-71.
1989: C L Manyak; G P Norton; C G Lobe; R Chris Bleackley; H K Gershenfeld; Irving L Weissman; V Kumar; Nolan Sigal; Gloria C Koo
IL-2 induces expression of serine protease enzymes and genes in natural killer and nonspecific T killer cells.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(10):3707-13.
1989: Craig Y Okada; Irving L Weissman
Relative V beta transcript levels in thymus and peripheral lymphoid tissues from various mouse strains. Inverse correlation of I-E and Mls expression with relative abundance of several V beta transcripts in peripheral lymphoid tissues.
The Journal of experimental medicine 1989;169(5):1703-19.
1989: Bernhard Holzmann; Irving L Weissman
Integrin molecules involved in lymphocyte homing to Peyer's patches.
Immunological reviews 1989;108():45-61.
1989: M H Siegelman; M van de Rijn; Irving L Weissman
Mouse lymph node homing receptor cDNA clone encodes a glycoprotein revealing tandem interaction domains.
Science (New York, N.Y.) 1989;243(4895):1165-72.
1989: G J Spangrude; J Klein; S Heimfeld; Y Aihara; Irving L Weissman
Two monoclonal antibodies identify thymic-repopulating cells in mouse bone marrow.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(2):425-30.
1989: Bernhard Holzmann; B W McIntyre; Irving L Weissman
Identification of a murine Peyer's patch--specific lymphocyte homing receptor as an integrin molecule with an alpha chain homologous to human VLA-4 alpha.
Cell 1989;56(1):37-46.
1989: S Heimfeld; Cynthia J Guidos; Bernhard Holzmann; M H Siegelman; Irving L Weissman
Developmental analysis of the mouse hematolymphoid system.
Cold Spring Harbor symposia on quantitative biology 1989;54 Pt 1():75-85.
1989: R J Hershberger; Christoph Mueller; H K Gershenfeld; Irving L Weissman
A serine protease-encoding gene that marks activated cytotoxic T cells in vivo and in vitro.
Current topics in microbiology and immunology 1989;140():81-92.
1989: C E Müller-Sieburg; G F Tidmarsh; Irving L Weissman; G J Spangrude
Maturation of hematolymphoid cells that express Thy-1.
Immunology series 1989;45():289-316.
1989: Irving L Weissman
Some observation on the life history of lymphocytes.
Harvey lectures 1989;85():43-69.
1988: R Namikawa; H Kaneshima; M Lieberman; Irving L Weissman; Joseph M McCune
Infection of the SCID-hu mouse by HIV-1.
Science (New York, N.Y.) 1988;242(4886):1684-6.
1988: T M Jung; W M Gallatin; Irving L Weissman; MO Dailey
Down-regulation of homing receptors after T cell activation.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(12):4110-7.
1988: G J Spangrude; Y Aihara; Irving L Weissman; J Klein
The stem cell antigens Sca-1 and Sca-2 subdivide thymic and peripheral T lymphocytes into unique subsets.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(11):3697-707.
1988: G S Wood; Christoph Mueller; Roger A Warnke; Irving L Weissman
In situ localization of HuHF serine protease mRNA and cytotoxic cell-associated antigens in human dermatoses. A novel method for the detection of cytotoxic cells in human tissues.
The American journal of pathology 1988;133(2):218-25.
1988: Joseph M McCune; R Namikawa; H Kaneshima; L D Shultz; M Lieberman; Irving L Weissman
The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function.
Science (New York, N.Y.) 1988;241(4873):1632-9.
1988: G J Spangrude; Irving L Weissman
Mature T cells generated from single thymic clones are phenotypically and functionally heterogeneous.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(6):1877-90.
1988: J A Harp; C B Tsuchida; Irving L Weissman; V L Scofield
Autoreactive blood cells and programmed cell death in growth and development of protochordates.
The Journal of experimental zoology 1988;247(3):257-62.
1988: Irving L Weissman
Was the MHC made for the immune system, or did immunity take advantage of an ancient polymorphic gene family encoding cell surface interaction molecules? A speculative essay.
International reviews of immunology 1988;3(4):397-416.
1988: G J Spangrude; S Heimfeld; Irving L Weissman
Purification and characterization of mouse hematopoietic stem cells.
Science (New York, N.Y.) 1988;241(4861):58-62.
1988: C E Müller-Sieburg; K Townsend; Irving L Weissman; D Rennick
Proliferation and differentiation of highly enriched mouse hematopoietic stem cells and progenitor cells in response to defined growth factors.
The Journal of experimental medicine 1988;167(6):1825-40.
1988: Rebecca Adkins; D Gandour; Samuel Strober; Irving L Weissman
Total lymphoid irradiation leads to transient depletion of the mouse thymic medulla and persistent abnormalities among medullary stromal cells.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(10):3373-9.
1988: G J Spangrude; C E Muller-Sieburg; S Heimfeld; Irving L Weissman
Two rare populations of mouse Thy-1lo bone marrow cells repopulate the thymus.
The Journal of experimental medicine 1988;167(5):1671-83.
1988: Joseph M McCune; L B Rabin; Mark B Feinberg; M Lieberman; J C Kosek; G R Reyes; Irving L Weissman
Endoproteolytic cleavage of gp160 is required for the activation of human immunodeficiency virus.
Cell 1988;53(1):55-67.
1988: Christoph Mueller; H K Gershenfeld; C G Lobe; Craig Y Okada; R C Bleackley; Irving L Weissman
Expression of two serine esterase genes during an allograft rejection in the mouse.
Transplantation proceedings 1988;20(2):251-3.
1988: Christoph Mueller; H K Gershenfeld; C G Lobe; Craig Y Okada; R C Bleackley; Irving L Weissman
A high proportion of T lymphocytes that infiltrate H-2-incompatible heart allografts in vivo express genes encoding cytotoxic cell-specific serine proteases, but do not express the MEL-14-defined lymph node homing receptor.
The Journal of experimental medicine 1988;167(3):1124-36.
1988: H K Gershenfeld; R J Hershberger; T B Shows; Irving L Weissman
Cloning and chromosomal assignment of a human cDNA encoding a T cell- and natural killer cell-specific trypsin-like serine protease.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(4):1184-8.
1988: Rebecca Adkins; G F Tidmarsh; Irving L Weissman
Normal thymic cortical epithelial cells developmentally regulate the expression of a B-lineage transformation-associated antigen.
Immunogenetics 1988;27(3):180-6.
1988: B T Sher; Robert Bargatze; Bernhard Holzmann; W M Gallatin; D Matthews; N Wu; Louis J Picker; Eugene C Butcher; Irving L Weissman
Homing receptors and metastasis.
Advances in cancer research 1988;51():361-90.
1988: H K Gershenfeld; R J Hershberger; Christoph Mueller; Irving L Weissman
A T cell- and natural killer cell-specific, trypsin-like serine protease. Implications of a cytolytic cascade.
Annals of the New York Academy of Sciences 1988;532():367-79.
1987: M Lieberman; G A Hansteen; Joseph M McCune; M L Scott; J H White; Irving L Weissman
Indirect induction of radiation lymphomas in mice. Evidence for a novel, transmissible leukemogen.
The Journal of experimental medicine 1987;166(6):1883-93.
1987: Robert Bargatze; N W Wu; Irving L Weissman; Eugene C Butcher
High endothelial venule binding as a predictor of the dissemination of passaged murine lymphomas.
The Journal of experimental medicine 1987;166(4):1125-31.
1987: S Ezine; L Jerabek; Irving L Weissman
The phenotype of thymocytes derived from a single clonogenic precursor.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(7):2195-9.
1987: C A Whitlock; G F Tidmarsh; C Muller-Sieburg; Irving L Weissman
Bone marrow stromal cell lines with lymphopoietic activity express high levels of a pre-B neoplasia-associated molecule.
Cell 1987;48(6):1009-21.
1987: Herbert C Morse; G F Tidmarsh; K L Holmes; T F Frederickson; J N Hartley; J H Pierce; W Y Langdon; M O Dailey; Irving L Weissman
Expression of the 6C3 antigen on murine hematopoietic neoplasms. Association with expression of abl, ras, fes, src, erbB, and Cas NS-1 oncogenes but not with myc.
The Journal of experimental medicine 1987;165(3):920-5.
1987: G S Tamura; Michael S McGrath; Irving L Weissman
Molecules recognized by anti-idiotypic monoclonal antibodies to the B cell lymphoma, BCL1.
The Journal of molecular and cellular immunology : JMCI 1987;3(4):243-53.
1986: G F Tidmarsh; M O Dailey; Irving L Weissman
Expression of a monoclonal antibody-defined, B-lineage transformation antigen specifically identifies Abelson-diseased animals. Genetically determined resistance to Abelson murine leukemia virus acts before induction of gp160(6C3).
The Journal of experimental medicine 1986;164(4):1356-61.
1986: K J Razzeca; E Pillemer; Irving L Weissman; robert rouse
In situ identification of idiotype-positive cells participating in the immune response to phosphorylcholine.
European journal of immunology 1986;16(4):393-9.
1986: C E Muller-Sieburg; C A Whitlock; Irving L Weissman
Isolation of two early B lymphocyte progenitors from mouse marrow: a committed pre-pre-B cell and a clonogenic Thy-1-lo hematopoietic stem cell.
Cell 1986;44(4):653-62.
1986: E A Pillemer; D A Kooistra; O N Witte; Irving L Weissman
Monoclonal antibody to the amino-terminal L sequence of murine leukemia virus glycosylated gag polyproteins demonstrates their unusual orientation in the cell membrane.
Journal of virology 1986;57(2):413-21.
1985: G F Tidmarsh; M O Dailey; C A Whitlock; E Pillemer; Irving L Weissman
Transformed lymphocytes from Abelson-diseased mice express levels of a B lineage transformation-associated antigen elevated from that found on normal lymphocytes.
The Journal of experimental medicine 1985;162(5):1421-34.
1985: MO Dailey; W M Gallatin; G Kraal; Eugene C Butcher; Irving L Weissman
T cell clones: a model of a non-recirculating phase of T cell differentiation.
Advances in experimental medicine and biology 1985;186():621-7.
1985: MO Dailey; W M Gallatin; Irving L Weissman
The in vivo behavior of T cell clones: altered migration due to loss of the lymphocyte surface homing receptor.
The Journal of molecular and cellular immunology : JMCI 1985;2(1):27-36.
1984: E Pillemer; C Whitlock; Irving L Weissman
Transformation-associated proteins in murine B-cell lymphomas that are distinct from Abelson virus gene products.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(14):4434-8.
1983: R L Coffman; Irving L Weissman
Immunoglobulin gene rearrangement during pre-B cell differentiation.
The Journal of molecular and cellular immunology : JMCI 1983;1(1):31-41.
1982: M O Dailey; E Pillemer; Irving L Weissman
Protection against syngeneic lymphoma by a long-lived cytotoxic T-cell clone.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(17):5384-7.
1982: MO Dailey; C G Fathman; E C Butcher; E Pillemer; Irving L Weissman
Abnormal migration of T lymphocyte clones.
Journal of immunology (Baltimore, Md. : 1950) 1982;128(5):2134-6.
1981: N Hollander; E Pillemer; Irving L Weissman
Effects of Lyt antibodies on T-cell functions: augmentation by anti-Lyt-1 as opposed to inhibition by anti-Lyt-2.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(2):1148-51.
1981: M S McGrath; L Jerabek; E Pillemer; R A Steinberg; Irving L Weissman
Receptor mediated murine leukemogenesis: monoclonal antibody induced lymphoma cell growth arrest.
Haematology and blood transfusion 1981;26():360-4.
1980: N Hollander; E Pillemer; Irving L Weissman
Blocking effect of lyt-2 antibodies on T cell functions.
The Journal of experimental medicine 1980;152(3):674-87.
1980: R Scollay; S Jacobs; L Jerabek; E Butcher; Irving L Weissman
T cell maturation: thymocyte and thymus migrant subpopulations defined with monoclonal antibodies to MHC region antigens.
Journal of immunology (Baltimore, Md. : 1950) 1980;124(6):2845-53.
1980: M S McGrath; E Pillemer; Irving L Weissman
Murine leukaemogenesis: monoclonal antibodies to T-cell determinants arrest T-lymphoma cell proliferation.
Nature 1980;285(5762):259-61.
1980: M S McGrath; E Pillemer; D A Kooistra; S Jacobs; L Jerabek; Irving L Weissman
T-lymphoma retroviral receptors and control of T-lymphoma cell proliferation.
Cold Spring Harbor symposia on quantitative biology 1980;44 Pt 2,():1297-304.
1980: M S McGrath; E Pillemer; D Kooistra; Irving L Weissman
The role of MuLV receptors on T-lymphoma cells in lymphoma cell proliferation.
Contemporary topics in immunobiology 1980;11():157-84.