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Thomas Wekerle

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TOP 3
Edda Mayer; Nina Pilat; Thomas Wekerle; Markus Hölzl; Sarah Ahmadi; Barbara Dillinger; Dietmar Fuchs; Andreas Heitger
CTLA4-Ig immunosuppressive activity at the level of dendritic cell/T cell crosstalk.
Haley Ramsey; Elisabeth Schwaiger; Christoph Schwarz; Lukas Unger; Ulrike Baranyi; Martina Gattringer; Karin Hock; Christoph Klaus; Nina Pilat; Fritz Wrba; Thomas Wekerle
Anti-LFA-1 or rapamycin overcome costimulation blockade-resistant rejection in sensitized bone marrow recipients.
Nina Pilat; Sebastian Schoppmann; Judith Stift; Thomas Wekerle; Peter Mazal; Gabriela A Berlakovich
No evidence for recipient-derived hepatocytes in serial biopsies of sex-mismatched liver transplants.

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2013: Edda Mayer; Nina Pilat; Thomas Wekerle; Markus Hölzl; Sarah Ahmadi; Barbara Dillinger; Dietmar Fuchs; Andreas Heitger
CTLA4-Ig immunosuppressive activity at the level of dendritic cell/T cell crosstalk.
International immunopharmacology 2013;15(3):638-45.
2013: Haley Ramsey; Elisabeth Schwaiger; Christoph Schwarz; Lukas Unger; Ulrike Baranyi; Martina Gattringer; Karin Hock; Christoph Klaus; Nina Pilat; Fritz Wrba; Thomas Wekerle
Anti-LFA-1 or rapamycin overcome costimulation blockade-resistant rejection in sensitized bone marrow recipients.
Transplant international : official journal of the European Society for Organ Transplantation 2013;26(2):206-18.
2012: Nina Pilat; Sebastian Schoppmann; Judith Stift; Thomas Wekerle; Peter Mazal; Gabriela A Berlakovich
No evidence for recipient-derived hepatocytes in serial biopsies of sex-mismatched liver transplants.
Transplantation 2012;94(9):953-7.
2012: U Baranyi; M Gattringer; J Iacomini; C Klaus; Birgit Linhart; Nina Pilat; E Schwaiger; Rudolf Valenta; Thomas Wekerle
Persistent molecular microchimerism induces long-term tolerance towards a clinically relevant respiratory allergen.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2012;42(8):1282-92.
2012: Nina Pilat; Christoph Schwarz; Thomas Wekerle
Modulating T-cell costimulation as new immunosuppressive concept in organ transplantation.
Current opinion in organ transplantation 2012;17(4):368-75.
2012: Nina Pilat; Thomas Wekerle
Belatacept and Tregs: friends or foes?
Immunotherapy 2012;4(4):351-4.
2012: Thomas Wekerle; Josep M Grinyó
Belatacept: from rational design to clinical application.
Transplant international : official journal of the European Society for Organ Transplantation 2012;25(2):139-50.
2011: Ivan Kristo; Julian Marschalek; Ferdinand Mühlbacher; Rainer Oberbauer; Thomas Wekerle; Julia Wilflingseder; Alexander Kainz; Martin Bodingbauer
Effect of intraportal infusion of tacrolimus on ischaemic reperfusion injury in orthotopic liver transplantation: a randomized controlled trial.
Transplant international : official journal of the European Society for Organ Transplantation 2011;24(9):912-9.
2011: Nina Pilat; Fritz Wrba; Ulrike Baranyi; Martina Gattringer; Dela Golshayan; Elmar Jaeckel; Christoph Klaus; Thomas Wekerle
Therapeutic efficacy of polyclonal tregs does not require rapamycin in a low-dose irradiation bone marrow transplantation model.
Transplantation 2011;92(3):280-8.
2011: Nina Pilat; Mohamed H Sayegh; Thomas Wekerle
Costimulatory pathways in transplantation.
Seminars in immunology 2011;23(4):293-303.
2011: Ulrike Baranyi; Katharina Blatt; Alexandra Boehm; Barbara Bohle; Margarete Focke-Tejkl; Martina Gattringer; Katharina Marth; Peter Valent; Rudolf Valenta; Thomas Wekerle
Expression of a major plant allergen as membrane-anchored and secreted protein in human cells with preserved T cell and B cell epitopes.
International archives of allergy and immunology 2011;156(3):259-66.
2011: Ulrike Baranyi; Martina Gattringer; Rudolf Valenta; Thomas Wekerle
Cell-based therapy in allergy.
Current topics in microbiology and immunology 2011;352():161-79.
2010: Patrick-Nikolaus Nierlich; Christoph Klaus; Sinda Bigenzahn; Nina Pilat; Zvonimir Koporc; Ines Pree; Ulrike Baranyi; Masaru Taniguchi; Ferdinand Muehlbacher; Thomas Wekerle
The role of natural killer T cells in costimulation blockade-based mixed chimerism.
Transplant international : official journal of the European Society for Organ Transplantation 2010;23(11):1179-89.
2010: Nina Pilat; Thomas Wekerle
Transplantation tolerance through mixed chimerism.
Nature reviews. Nephrology 2010;6(10):594-605.
2010: Nina Pilat; U Baranyi; C Klaus; E Jaeckel; N Mpofu; Fritz Wrba; D Golshayan; Ferdinand Muehlbacher; Thomas Wekerle
Treg-therapy allows mixed chimerism and transplantation tolerance without cytoreductive conditioning.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2010;10(4):751-62.
2009: Nina Pilat; Christoph Klaus; Elisabeth Schwaiger; Thomas Wekerle
Hurdles to the induction of tolerogenic mixed chimerism.
Transplantation 2009;87(9 Suppl):S79-84.
2009: Ulrike Baranyi; Nina Pilat; Martina Gattringer; Thomas Wekerle
A chimerism-based approach to induce tolerance in IgE-mediated allergy.
Critical reviews in immunology 2009;29(5):379-97.
2009: Ines Pree; Nina Pilat; Thomas Wekerle
Bone marrow transplantation as a strategy for tolerance induction in the clinic.
Frontiers in bioscience : a journal and virtual library 2009;14():611-20.
2008: Thomas Wekerle
T-regulatory cells-what relationship with immunosuppressive agents?
Transplantation proceedings 2008;40(10 Suppl):S13-6.
2008: Zvonimir Koporc; Nina Pilat; P Nierlich; Peter Blaha; Sinda Bigenzahn; Ines Pree; Edgar Selzer; Megan Sykes; Ferdinand Muehlbacher; Thomas Wekerle
Murine mobilized peripheral blood stem cells have a lower capacity than bone marrow to induce mixed chimerism and tolerance.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2008;8(10):2025-36.
2008: Thomas Fehr; Sophia Wang; Fabienne Haspot; Josef Kurtz; Peter Blaha; Timothy Hogan; Meredith Chittenden; Thomas Wekerle; Megan Sykes
Rapid deletional peripheral CD8 T cell tolerance induced by allogeneic bone marrow: role of donor class II MHC and B cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(6):4371-80.
2008: Ulrike Baranyi; Birgit Linhart; Nina Pilat; Martina Gattringer; Jessamyn Bagley; Ferdinand Muehlbacher; John Iacomini; Rudolf Valenta; Thomas Wekerle
Tolerization of a type I allergic immune response through transplantation of genetically modified hematopoietic stem cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(12):8168-75.
2007: Martin Bodingbauer; Thomas Wekerle; B Pakrah; Paul Roschger; Markus Peck-Radosavljevic; Gerd Silberhumer; Stephan Grampp; Susanne Rockenschaub; Gabriela A Berlakovich; Rudolf Steininger; Klaus Klaushofer; Rainer Oberbauer; Ferdinand Mühlbacher
Prophylactic bisphosphonate treatment prevents bone fractures after liver transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2007;7(7):1763-9.
2007: Ines Pree; Sinda Bigenzahn; Dietmar Fuchs; Zvonimir Koporc; Patrick Nierlich; Christiana Winkler; Gerald Brandacher; Megan Sykes; Ferdinand Muehlbacher; Felix Langer; Thomas Wekerle
CTLA4Ig promotes the induction of hematopoietic chimerism and tolerance independently of Indoleamine-2,3-dioxygenase.
Transplantation 2007;83(5):663-7.
2007: Gerd Silberhumer; Herwig Pokorny; Hubert Hetz; Harald Herkner; Susanne Rasoul-Rockenschaub; Thomas Soliman; Thomas Wekerle; Gabriela A Berlakovich; Rudolf Steininger; Ferdinand Muehlbacher
Combination of extended donor criteria and changes in the Model for End-Stage Liver Disease score predict patient survival and primary dysfunction in liver transplantation: a retrospective analysis.
Transplantation 2007;83(5):588-92.
2007: Birgit Linhart; Sinda Bigenzahn; Arnulf Hartl; Christian Lupinek; Josef Thalhamer; Rudolf Valenta; Thomas Wekerle
Costimulation blockade inhibits allergic sensitization but does not affect established allergy in a murine model of grass pollen allergy.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(6):3924-31.
2007: Martin Bodingbauer; reinhard kramar; Thomas Wekerle; Georg A Böhmig; Gabriela A Berlakovich; Marcus D Säemann; Rudolf Steininger; Paul Perco; Rainer Oberbauer; Walter H Hörl; Ferdinand Mühlbacher
Present status at the Vienna Transplantation Center after four thousand renal transplantations.
Clinical transplants 2007;():69-80.
2007: Ines Pree; Thomas Wekerle
Inducing mixed chimerism and transplantation tolerance through allogeneic bone marrow transplantation with costimulation blockade.
Methods in molecular biology (Clifton, N.J.) 2007;380():391-403.
2007: Ines Pree; Nina Pilat; Thomas Wekerle
Recent progress in tolerance induction through mixed chimerism.
International archives of allergy and immunology 2007;144(3):254-66.
2006: Martin Bodingbauer; B Pakrah; Rudolf Steininger; Gabriela A Berlakovich; Susanne Rockenschaub; Thomas Wekerle; Ferdinand Muehlbacher
The advantage of allocating kidneys from old cadaveric donors to old recipients: a single-center experience.
Clinical transplantation 2006;20(4):471-5.
2006: Zvonimir Koporc; Sinda Bigenzahn; Peter Blaha; Elahi Fariborz; Edgar Selzer; Megan Sykes; Ferdinand Muehlbacher; Thomas Wekerle
Induction of mixed chimerism through transplantation of CD45-congenic mobilized peripheral blood stem cells after nonmyeloablative irradiation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2006;12(3):284-92.
2006: Paul Perco; Peter Blaha; Alexander Kainz; Bernd Mayer; Peter Hauser; Thomas Wekerle; Rainer Oberbauer
Molecular signature of mice T lymphocytes following tolerance induction by allogeneic BMT and CD40-CD40L costimulation blockade.
Transplant international : official journal of the European Society for Organ Transplantation 2006;19(2):146-57.
2005: Thomas Fehr; Yasuo Takeuchi; Josef Kurtz; Thomas Wekerle; Megan Sykes
Early regulation of CD8 T cell alloreactivity by CD4+CD25- T cells in recipients of anti-CD154 antibody and allogeneic BMT is followed by rapid peripheral deletion of donor-reactive CD8+ T cells, precluding a role for sustained regulation.
European journal of immunology 2005;35(9):2679-90.
2005: Peter Blaha; Sinda Bigenzahn; Zvonimir Koporc; Megan Sykes; Ferdinand Muehlbacher; Thomas Wekerle
Short-term immunosuppression facilitates induction of mixed chimerism and tolerance after bone marrow transplantation without cytoreductive conditioning.
Transplantation 2005;80(2):237-43.
2005: Sinda Bigenzahn; Peter Blaha; Zvonimir Koporc; Ines Pree; Edgar Selzer; Helga Bergmeister; Fritz Wrba; Christoph Heusser; Kathrin Wagner; Ferdinand Muehlbacher; Thomas Wekerle
The role of non-deletional tolerance mechanisms in a murine model of mixed chimerism with costimulation blockade.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2005;5(6):1237-47.
2004: Tudor Bîrsan; Christiane Loinig; Martin Bodingbauer; Thomas Wekerle; Susanne Rockenschaub; Gabriela A Berlakovich; Thomas Soliman; Ferdinand Mühlbacher; Rudolf Steininger
Comparison between C0 and C2 monitoring in de novo renal transplant recipients: retrospective analysis of a single-center experience.
Transplantation 2004;78(12):1787-91.
2004: Marcus D Säemann; Maximilian Zeyda; Thomas M Stulnig; Georg A Böhmig; Thomas Wekerle; Walter H Hörl; Gerhard J Zlabinger
Janus kinase-3 (JAK3) inhibition: a novel immunosuppressive option for allogeneic transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 2004;17(9):481-9.
2004: Josef Kurtz; Thomas Wekerle; Megan Sykes
Tolerance in mixed chimerism - a role for regulatory cells?
Trends in immunology 2004;25(10):518-23.
2004: Thomas Wekerle; Megan Sykes
Induction of tolerance.
Surgery 2004;135(4):359-64.
2004: Yasuo Takeuchi; Hiroshi Ito; Josef Kurtz; Thomas Wekerle; Leon Ho; Megan Sykes
Earlier low-dose TBI or DST overcomes CD8+ T-cell-mediated alloresistance to allogeneic marrow in recipients of anti-CD40L.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2004;4(1):31-40.
2003: Thomas Wekerle; Peter Blaha; Zvonimir Koporc; Sinda Bigenzahn; Michael Pusch; Ferdinand Muehlbacher
Mechanisms of tolerance induction through the transplantation of donor hematopoietic stem cells: central versus peripheral tolerance.
Transplantation 2003;75(9 Suppl):21S-25S.
2003: Peter Blaha; Sinda Bigenzahn; Zvonimir Koporc; Maximilian Schmid; Felix Langer; Edgar Selzer; Helga Bergmeister; Fritz Wrba; Josef Kurtz; Christopher Kiss; Erich Roth; Ferdinand Muehlbacher; Megan Sykes; Thomas Wekerle
The influence of immunosuppressive drugs on tolerance induction through bone marrow transplantation with costimulation blockade.
Blood 2003;101(7):2886-93.
2002: Thomas Wekerle; Josef Kurtz; Sinda Bigenzahn; Yasuo Takeuchi; Megan Sykes
Mechanisms of transplant tolerance induction using costimulatory blockade.
Current opinion in immunology 2002;14(5):592-600.
2002: Thomas Wekerle; Peter Blaha; Felix Langer; Maximilian Schmid; Ferdinand Muehlbacher
Tolerance through bone marrow transplantation with costimulation blockade.
Transplant immunology 2002;9(2-4):125-33.
2002: Thomas Wekerle; Boris Nikolic; Denise A Pearson; Kirsten G Swenson; Megan Sykes
Minimal conditioning required in a murine model of T cell depletion, thymic irradiation and high-dose bone marrow transplantation for the induction of mixed chimerism and tolerance.
Transplant international : official journal of the European Society for Organ Transplantation 2002;15(5):248-53.
2001: Thomas Wekerle; Reza Asari; Martin Bodingbauer; F Mühlbacher
Waking the dead.
Lancet 2001;358(9296):1907.
2001: Josef Kurtz; Hiroshi Ito; Thomas Wekerle; Juanita Shaffer; Megan Sykes
Mechanisms involved in the establishment of tolerance through costimulatory blockade and BMT: lack of requirement for CD40L-mediated signaling for tolerance or deletion of donor-reactive CD4+ cells.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2001;1(4):339-49.
2001: Thomas Wekerle
Transplantation tolerance induced by mixed chimerism.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2001;20(8):816-23.
2001: Thomas Wekerle; Josef Kurtz; Mohamed H Sayegh; Hiroshi Ito; A Wells; S Bensinger; Juanita Shaffer; Laurence A Turka; Megan Sykes
Peripheral deletion after bone marrow transplantation with costimulatory blockade has features of both activation-induced cell death and passive cell death.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(4):2311-6.
2001: Thomas Wekerle; Megan Sykes
Mixed chimerism and transplantation tolerance.
Annual review of medicine 2001;52():353-70.
2000: Yong Zhao; Kirsten G Swenson; Thomas Wekerle; Jose-Ignacio Rodriguez-Barbosa; J Scott Arn; Megan Sykes
The critical role of mouse CD4+ cells in the rejection of highly disparate xenogeneic pig thymus grafts.
Xenotransplantation 2000;7(2):129-37.
2000: Thomas Wekerle; Josef Kurtz; Hiroshi Ito; J V Ronquillo; Victor M Dong; Guiling Zhao; Juanita Shaffer; Mohamed H Sayegh; Megan Sykes
Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment.
Nature medicine 2000;6(4):464-9.
1999: Georg A Böhmig; Peter-Michael Krieger; Marcus D Säemann; R Ullrich; H Karimi; Thomas Wekerle; Ferdinand Mühlbacher; Gerhard J Zlabinger
Stable prodrugs of n-butyric acid: suppression of T cell alloresponses in vitro and prolongation of heart allograft survival in a fully allogeneic rat strain combination.
Transplant immunology 1999;7(4):221-7.
1999: Thomas Wekerle; Mohamed H Sayegh; Hiroshi Ito; J Hill; Anil Chandraker; Denise A Pearson; Kirsten G Swenson; Guiling Zhao; Megan Sykes
Anti-CD154 or CTLA4Ig obviates the need for thymic irradiation in a non-myeloablative conditioning regimen for the induction of mixed hematopoietic chimerism and tolerance.
Transplantation 1999;68(9):1348-55.
1999: Thomas Wekerle; Megan Sykes
Mixed chimerism as an approach for the induction of transplantation tolerance.
Transplantation 1999;68(4):459-67.
1999: Thomas Wekerle; Mohamed H Sayegh; Anil Chandraker; Kirsten G Swenson; Yong Zhao; Megan Sykes
Role of peripheral clonal deletion in tolerance induction with bone marrow transplantation and costimulatory blockade.
Transplantation proceedings 1999;31(1-2):680.
1998: Thomas Wekerle; M H Sayegh; J Hill; Yong Zhao; Anil Chandraker; Kirsten G Swenson; Guiling Zhao; Megan Sykes
Extrathymic T cell deletion and allogeneic stem cell engraftment induced with costimulatory blockade is followed by central T cell tolerance.
The Journal of experimental medicine 1998;187(12):2037-44.
1998: Megan Sykes; GL Szot; Kirsten G Swenson; Denise A Pearson; Thomas Wekerle
Separate regulation of peripheral hematopoietic and thymic engraftment.
Experimental hematology 1998;26(6):457-65.
1998: Thomas Wekerle; S Eichinger; A Maier; F Wrba; P Möschl
Intrahepatic splenic tissue in a patient with recurrent idiopathic thrombocytopenic purpura.
Surgery 1998;123(5):596-9.
1998: Thomas Wekerle; Walter Klepetko; Shahrokh Taghavi; Tudor Birsan
Lung transplantation for primary pulmonary hypertension and giant pulmonary artery aneurysm.
The Annals of thoracic surgery 1998;65(3):825-7.
1997: Thomas Wekerle; Walter Klepetko; Wilfried Wisser; Omer Senbaklavaci; Omeros Artemiou; Andreas Zuckermann; Ernst Wolner
Incidence and outcome of major non-pulmonary surgical procedures in lung transplant recipients.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 1997;12(5):718-23.
1997: Omeros Artemiou; Georg Wieselthaler; Andreas Zuckermann; Wilfried Wisser; Thomas Wekerle; Omer Senbaklavaci; Tudor Birsan; Gerhard Dekan; M Kritzinger; Walter Klepetko
Downsizing of the donor lung: peripheral segmental resections and lobar transplantation.
Transplantation proceedings 1997;29(7):2899-900.
1996: Wilfried Wisser; Thomas Wekerle; Gerhard J Zlabinger; O Senbaclavaci; Andreas Zuckermann; Walter Klepetko; Ernst Wolner
Influence of human leukocyte antigen matching on long-term outcome after lung transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 1996;15(12):1209-16.
1996: Thomas Wekerle; G Zlabinger
HLA matching and outcome of heart transplantation.
Lancet 1996;347(9006):979-80.
1996: Wilfried Wisser; Walter Klepetko; Thomas Wekerle; Günther Laufer; Anton Stift; Michael Hiesmayr; W Schlick
Tailoring of the lung to overcome size disparities in lung transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 1996;15(3):239-42.
1996: Thomas Wekerle; Walter Klepetko; Wilfried Wisser; Omer Senbaklavaci; Reinhard Moidl; M Hiesmayer; Edda M Tschernko; Ernst Wolner
Lung retransplantation: institutional report on a series of twenty patients.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 1996;15(2):182-9.
1996: Georg A Böhmig; Thomas Wekerle; Marcus D Säemann; Josef Kovarik; Gerhard J Zlabinger
Induction of alloantigen-specific hyporesponsiveness in vitro by n-butyrate: antagonistic effect of cyclosporin A.
Transplant international : official journal of the European Society for Organ Transplantation 1996;9 Suppl 1():S318-22.
1995: Wilfried Wisser; H Ringl; Thomas Wekerle; Ernst Wolner; Walter Klepetko
A new flush solution for extended lung preservation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 1995;14(2):289-95.
1994: Adelheid End; Gerhard Dekan; M Korn; T Helbich; Martin Grabenwöger; Gerlinde Mitterbauer; Anton Stift; P Mares; Thomas Wekerle; Ernst Wolner
[Differential diagnosis of round opacities after lung transplantation].
Deutsche medizinische Wochenschrift (1946) 1994;119(33):1105-9.
1993: Wilfried Wisser; D Oturanlar; R Minich; H Ringl; Thomas Wekerle; Walter Klepetko; Ernst Wolner
Closed circuit perfusion of an isolated rabbit lung. A new model for the evaluation of preservation quality of stored lungs.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 1993;7(2):71-4.
1992: D Oturanlar; Walter Klepetko; Michael Grimm; Adelheid End; Wilfried Wisser; Thomas Wekerle; Ernst Wolner
Management of severe bronchial ischemia after bilateral sequential lung transplantation.
The Annals of thoracic surgery 1992;54(6):1221-2.