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Babette Weksler

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Payam Fallahi; Sidney W Fu; Richard Katz; Yinglei Lai; David Leitenberg; Ranyang Li; Yi Lian; Lorraine Marshall; Frederik Rebling; Jonathan Reiner; Frederick Rickles; Ian Toma; Kiersten Vanhouten; Babette B Weksler; Zhaoqing Yang; Sujata Bupp; Larry Carpio; Timothy A McCaffrey
Aspirin insensitive thrombophilia: Transcript profiling of blood identifies platelet abnormalities and HLA restriction.
Marc E Weksler; Marcus M Reidenberg; Norman R Relkin; Paul Szabo; Babette B Weksler; Antonia M W Coppus
Alzheimer's disease and Down's syndrome: Treating two paths to dementia.
Enrico Cristante; Jordi Lopez-Tremoleda; Elisa Maggioli; Andrea Malaspina; Claudio Mauro; Simon McArthur; Ignacio A Romero; Helen C Christian; Pierre O Couraud; Babette B Weksler; Marzena Wylezinska-Arridge; Egle Solito
Identification of an essential endogenous regulator of blood-brain barrier integrity, and its pathological and therapeutic implications.

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2013: Payam Fallahi; Sidney W Fu; Richard Katz; Yinglei Lai; David Leitenberg; Ranyang Li; Yi Lian; Lorraine Marshall; Frederik Rebling; Jonathan Reiner; Frederick Rickles; Ian Toma; Kiersten Vanhouten; Babette B Weksler; Zhaoqing Yang; Sujata Bupp; Larry Carpio; Timothy A McCaffrey
Aspirin insensitive thrombophilia: Transcript profiling of blood identifies platelet abnormalities and HLA restriction.
Gene 2013;520(2):131-8.
2013: Marc E Weksler; Marcus M Reidenberg; Norman R Relkin; Paul Szabo; Babette B Weksler; Antonia M W Coppus
Alzheimer's disease and Down's syndrome: Treating two paths to dementia.
Autoimmunity reviews 2013;12(6):670-3.
2013: Enrico Cristante; Jordi Lopez-Tremoleda; Elisa Maggioli; Andrea Malaspina; Claudio Mauro; Simon McArthur; Ignacio A Romero; Helen C Christian; Pierre O Couraud; Babette B Weksler; Marzena Wylezinska-Arridge; Egle Solito
Identification of an essential endogenous regulator of blood-brain barrier integrity, and its pathological and therapeutic implications.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(3):832-41.
2012: Silvia S Barbieri; Sara Gianellini; Louise R Howe; Luciana Mussoni; Eva Tarantino; Fabrizio Veglia; Babette B Weksler; Elena Zacchi; Patrizia Amadio; Elena Tremoli
Cyclooxygenase-2-derived prostacyclin regulates arterial thrombus formation by suppressing tissue factor in a sirtuin-1-dependent-manner.
Circulation 2012;126(11):1373-84.
2012: Toni K Roberts; Ignacio A Romero; Babette B Weksler; Pierre-Olivier Couraud; Eliseo Eugenin; Lillie Lopez; Joan W Berman
CCL2 disrupts the adherens junction: implications for neuroinflammation.
Laboratory investigation; a journal of technical methods and pathology 2012;92(8):1213-33.
2012: Guillaume Bussone; Cynthia Calzas; Hanadi Dib; Khaldoun Ghazal; Loïc Guillevin; Marc Humbert; Nada Kherbeck; Younes Sahbatou; Claire Sanson; Gérald Simonneau; Mathieu C Tamby; Franck Verrecchia; Babette B Weksler; Véronique Witko-Sarsat; Azzedine Yaici; Cédric Broussard; Luc Mouthon
IgG from patients with pulmonary arterial hypertension and/or systemic sclerosis binds to vascular smooth muscle cells and induces cell contraction.
Annals of the rheumatic diseases 2012;71(4):596-605.
2012: Willem Bintig; Pierre-Olivier Couraud; Lutz Dreyer; Linda Gerhard; Natalija Hohnjec; Maria Pangalos; Ignacio A Romero; Barbara Schlingmann; Babette B Weksler; Daniela Begandt; Anaclet Ngezahayo
Purine receptors and Ca(2+) signalling in the human blood-brain barrier endothelial cell line hCMEC/D3.
Purinergic signalling 2012;8(1):71-80.
2012: Christopher P Watson; Babette B Weksler; David J Begley; Pierre O Couraud; Murat Dogruel; Larisa Mihoreanu; Ignacio A Romero; Sarah A Thomas
The transport of nifurtimox, an anti-trypanosomal drug, in an in vitro model of the human blood-brain barrier: evidence for involvement of breast cancer resistance protein.
Brain research 2012;1436():111-21.
2012: Christian Freese; Matthew Gibson; Pierre-Olivier Couraud; Ignacio A Romero; Chiara Uboldi; Ronald E Unger; Babette B Weksler; C James Kirkpatrick
Uptake and cytotoxicity of citrate-coated gold nanospheres: Comparative studies on human endothelial and epithelial cells.
Particle and fibre toxicology 2012;9():23.
2012: Marc E Weksler; Babette B Weksler
The epidemic of distraction.
Gerontology 2012;58(5):385-90.
2012: Anja Schrade; Babette B Weksler; Pierre-Olivier Couraud; Ignacio A Romero; Hadassah Sade; Jens Niewoehner
Expression and localization of claudins-3 and -12 in transformed human brain endothelium.
Fluids and barriers of the CNS 2012;9():6.
2011: Silvia S Barbieri; Sara Gianellini; Babette B Weksler; Elena Zacchi; Patrizia Amadio; Elena Tremoli
Tobacco smoke regulates the expression and activity of microsomal prostaglandin E synthase-1: role of prostacyclin and NADPH-oxidase.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011;25(10):3731-40.
2011: Silvia S Barbieri; Elena Zacchi; Patrizia Amadio; Sara Gianellini; Luciana Mussoni; Babette B Weksler; Elena Tremoli
Cytokines present in smokers' serum interact with smoke components to enhance endothelial dysfunction.
Cardiovascular research 2011;90(3):475-83.
2010: Raktima Bhattacharya; Yan Xu; Md Ashequr Rahman; Pierre-Olivier Couraud; Ignacio Romero; Babette B Weksler; Jon A Weidanz; Ulrich Bickel
A novel vascular targeting strategy for brain-derived endothelial cells using a TCR mimic antibody.
Journal of cellular physiology 2010;225(3):664-72.
2010: Stephen M Carl; David J Lindley; Pierre O Couraud; Babette B Weksler; Ignacio Romero; Stephanie A Mowery; Gregory T Knipp
ABC and SLC transporter expression and pot substrate characterization across the human CMEC/D3 blood-brain barrier cell line.
Molecular pharmaceutics 2010;7(4):1057-68.
2009: Servio H Ramirez; Raghava Potula; Shongshan Fan; Tess Eidem; Anil Papugani; Nancy Reichenbach; Holly Dykstra; Babette B Weksler; Ignacio Romero; Pierre O Couraud; Yuri Persidsky
Methamphetamine disrupts blood-brain barrier function by induction of oxidative stress in brain endothelial cells.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2009;29(12):1933-45.
2009: Shannon L Joice; Firdaus Mydeen; Pierre-Olivier Couraud; Babette B Weksler; Ignacio Romero; Paul A Fraser; Alexander S Easton
Modulation of blood-brain barrier permeability by neutrophils: in vitro and in vivo studies.
Brain research 2009;1298():13-23.
2009: Mathieu Coureuil; Guillain Mikaty; Florence Miller; Hervé Lécuyer; Christine Bernard; Sandrine Bourdoulous; Guillaume Duménil; René-Marc Mège; Babette B Weksler; Ignacio Romero; Pierre-Olivier Couraud; Xavier Nassif
Meningococcal type IV pili recruit the polarity complex to cross the brain endothelium.
Science (New York, N.Y.) 2009;325(5936):83-7.
2009: Silvia Fischer; Miwako Nishio; Saskia C Peters; Marlene Tschernatsch; Maureen Walberer; Susanne Weidemann; Regina Heidenreich; Pierre O Couraud; Babette B Weksler; Ignacio Romero; Tibo Gerriets; Klaus T Preissner
Signaling mechanism of extracellular RNA in endothelial cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(7):2100-9.
2009: Louise Hurst; R A D Bunning; Pierre-Olivier Couraud; Ignacio Romero; Babette B Weksler; Basil Sharrack; M Nicola Woodroofe
Expression of ADAM-17, TIMP-3 and fractalkine in the human adult brain endothelial cell line, hCMEC/D3, following pro-inflammatory cytokine treatment.
Journal of neuroimmunology 2009;210(1-2):108-12.
2009: Ryan C Branski; Silvia S Barbieri; Babette B Weksler; Benjamin E. Saltman; Priya Krishna; Dennis H Kraus; Nalini V Broadbelt; Jie Chen; Dix P Poppas; Diane Felsen
Effects of transforming growth factor-beta1 on human vocal fold fibroblasts.
The Annals of otology, rhinology, and laryngology 2009;118(3):218-26.
2008: Imola Wilhelm; Péter Nagyoszi; Attila E Farkas; Pierre-Olivier Couraud; Ignacio Romero; Babette B Weksler; Csilla Fazakas; Ngo Thi Khue Dung; Sándor Bottka; Hannelore Bauer; Hans-Christian Bauer; István A Krizbai
Hyperosmotic stress induces Axl activation and cleavage in cerebral endothelial cells.
Journal of neurochemistry 2008;107(1):116-26.
2008: Joseph C Lim; Katarzyna Kania; Hasini Wijesuriya; Sangeeta Chawla; Jaswinder Sethi; Lukasz Pulaski; Ignacio Romero; Pierre-Olivier Couraud; Babette B Weksler; Stephen B Hladky; Margery A Barrand
Activation of beta-catenin signalling by GSK-3 inhibition increases p-glycoprotein expression in brain endothelial cells.
Journal of neurochemistry 2008;106(4):1855-65.
2008: Kai-Li He; Arunkumar B Deora; Huabao Xiong; Qi Ling; Babette B Weksler; Ruben Niesvizky; Katherine A Hajjar
Endothelial cell annexin A2 regulates polyubiquitination and degradation of its binding partner S100A10/p11.
The Journal of biological chemistry 2008;283(28):19192-200.
2008: Silvia Barbieri; Luca Ruggiero; Elena Tremoli; Babette B Weksler
Suppressing PTEN activity by tobacco smoke plus interleukin-1beta modulates dissociation of VE-cadherin/beta-catenin complexes in endothelium.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(4):732-8.
2007: Gerty Schreibelt; Gijs Kooij; Arie Reijerkerk; Ruben van Doorn; Sonja I Gringhuis; Susanne M A van der Pol; Babette B Weksler; Ignacio Romero; Pierre-Olivier Couraud; Jörg Piontek; Ingolf E Blasig; Christine D Dijkstra; Eric Ronken; Helga E de Vries
Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(13):3666-76.
2007: Imola Wilhelm; Attila E Farkas; Péter Nagyoszi; György Váró; Zoltán Bálint; Gergely A Végh; Pierre-Olivier Couraud; Ignacio Romero; Babette B Weksler; István A Krizbai
Regulation of cerebral endothelial cell morphology by extracellular calcium.
Physics in medicine and biology 2007;52(20):6261-74.
2007: Neil D Gross; Jay O Boyle; Baoheng Du; Vikram D Kekatpure; Agnieszka Lantowski; Howard T Thaler; Babette B Weksler; Kotha Subbaramaiah; Andrew J Dannenberg
Inhibition of Jun NH2-terminal kinases suppresses the growth of experimental head and neck squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(19):5910-7.
2007: Nathalie Gallay; Ludovic Anani; Adriana Lopez; Philippe Colombat; Christian Binet; Jorge Domenech; Babette B Weksler; Fabio Malavasi; Olivier Herault
The role of platelet/endothelial cell adhesion molecule 1 (CD31) and CD38 antigens in marrow microenvironmental retention of acute myelogenous leukemia cells.
Cancer research 2007;67(18):8624-32.
2007: BLANCHE ALTER; Gabriela M Baerlocher; Sharon A Savage; STEPHEN CHANOCK; Babette B Weksler; Judith P Willner; June A Peters; Neelam Giri; Peter M Lansdorp
Very short telomere length by flow fluorescence in situ hybridization identifies patients with dyskeratosis congenita.
Blood 2007;110(5):1439-47.
2007: Philippe V Afonso; Simona Ozden; Marie-Christine Prevost; Christine Schmitt; Danielle Seilhean; Babette B Weksler; Pierre-Olivier Couraud; Antoine Gessain; Ignacio Romero; Pierre-Emmanuel Ceccaldi
Human blood-brain barrier disruption by retroviral-infected lymphocytes: role of myosin light chain kinase in endothelial tight-junction disorganization.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(4):2576-83.
2007: Silvia S Barbieri; Babette B Weksler
Tobacco smoke cooperates with interleukin-1beta to alter beta-catenin trafficking in vascular endothelium resulting in increased permeability and induction of cyclooxygenase-2 expression in vitro and in vivo.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(8):1831-43.
2007: Ellinor I B Peerschke; Richard T Silver; Babette B Weksler; Wei Yin; Bernard Bernhardt; David Varon
Examination of platelet function in whole blood under dynamic flow conditions with the cone and plate(let) analyzer: effect of erythrocytosis and thrombocytosis.
American journal of clinical pathology 2007;127(3):422-8.
2007: Wei Yin; Berhane Ghebrehiwet; Babette B Weksler; Ellinor I B Peerschke
Classical pathway complement activation on human endothelial cells.
Molecular immunology 2007;44(9):2228-34.
2007: Daniel F Catanzaro; Ying Zhou; Rong Chen; Fangmin Yu; Sarah E Catanzaro; Mariana S De Lorenzo; Kotha Subbaramaiah; Xi Kathy Zhou; Domenico Pratico'; Andrew J Dannenberg; Babette B Weksler
Potentially reduced exposure cigarettes accelerate atherosclerosis: evidence for the role of nicotine.
Cardiovascular toxicology 2007;7(3):192-201.
2006: Marika Massaro; Aida Habib; Laura Lubrano; Serena Del Turco; Guido Lazzerini; todd bourcier; Babette B Weksler; Raffaele De Caterina
The omega-3 fatty acid docosahexaenoate attenuates endothelial cyclooxygenase-2 induction through both NADP(H) oxidase and PKC epsilon inhibition.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(41):15184-9.
2006: Sharon A Savage; Brian J Stewart; Babette B Weksler; Gabriela M Baerlocher; Peter M Lansdorp; STEPHEN CHANOCK; BLANCHE ALTER
Mutations in the reverse transcriptase component of telomerase (TERT) in patients with bone marrow failure.
Blood cells, molecules & diseases 2006;37(2):134-6.
2005: Eduardo A Salvati; Alejandro González Della Valle; Geoffrey H Westrich; Adam J Rana; Lawrence Specht; Babette B Weksler; Ping Wang; Charles Glueck
The John Charnley Award: heritable thrombophilia and development of thromboembolic disease after total hip arthroplasty.
Clinical orthopaedics and related research 2005;441():40-55.
2005: Babette B Weksler; E A Subileau; Nicolas Perrière; Pierre Charneau; K Holloway; M Leveque; H Tricoire-Leignel; A Nicotra; Sandrine Bourdoulous; P Turowski; David Male; Françoise Roux; John Greenwood; Ignacio Romero; Pierre-Olivier Couraud
Blood-brain barrier-specific properties of a human adult brain endothelial cell line.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(13):1872-4.
2005: Dimitrios Moraitis; Baoheng Du; Mariana S De Lorenzo; Jay O Boyle; Babette B Weksler; Erik G Cohen; John F Carew; Nasser K Altorki; Levy Kopelovich; Kotha Subbaramaiah; Andrew J Dannenberg
Levels of cyclooxygenase-2 are increased in the oral mucosa of smokers: evidence for the role of epidermal growth factor receptor and its ligands.
Cancer research 2005;65(2):664-70.
2005: Anita Aggarwal; R Grewal; R J Green; L Boggio; D Green; Babette B Weksler; Adrian Wiestner; Geraldine P Schechter
Rituximab for autoimmune haemophilia: a proposed treatment algorithm.
Haemophilia : the official journal of the World Federation of Hemophilia 2005;11(1):13-9.
2004: Daiva Bironaite; David Siegel; Julie L Moran; Babette B Weksler; David Ross
Stimulation of endothelial IL-8 (eIL-8) production and apoptosis by phenolic metabolites of benzene in HL-60 cells and human bone marrow endothelial cells.
Chemico-biological interactions 2004;149(2-3):177-88.
2004: Ellinor I B Peerschke; Richard T Silver; Babette B Weksler; Sage E Grigg; Naphtali Savion; David Varon
Ex vivo evaluation of erythrocytosis-enhanced platelet thrombus formation using the cone and plate(let) analyzer: effect of platelet antagonists.
British journal of haematology 2004;127(2):195-203.
2004: Bojana B Beleslin-Cokic; Vladan P Cokic; Xiaobing Yu; Babette B Weksler; Alan N Schechter; Constance Tom Noguchi
Erythropoietin and hypoxia stimulate erythropoietin receptor and nitric oxide production by endothelial cells.
Blood 2004;104(7):2073-80.
2004: Daiva Bironaite; David Siegel; Julie L Moran; Babette B Weksler; David Ross
Stimulation of endothelial IL-8 (eIL-8) production and apoptosis by phenolic metabolites of benzene in HL-60 cells and human bone marrow endothelial cells.
Chemico-biological interactions 2004;149(1):37-49.
2002: Geoffrey H Westrich; Babette B Weksler; Charles Glueck; Brianne F Blumenthal; Eduardo A Salvati
Correlation of thrombophilia and hypofibrinolysis with pulmonary embolism following total hip arthroplasty: an analysis of genetic factors.
The Journal of bone and joint surgery. American volume 2002;84-A(12):2161-7.
2002: Adrian Wiestner; Hearn J Cho; Adam S Asch; Mary Ann Michelis; Jack A Zeller; Ellinor I B Peerschke; Babette B Weksler; Geraldine P Schechter
Rituximab in the treatment of acquired factor VIII inhibitors.
Blood 2002;100(9):3426-8.
2000: Egle Solito; Ignacio Romero; Stefano Marullo; Françoise Russo-Marie; Babette B Weksler
Annexin 1 binds to U937 monocytic cells and inhibits their adhesion to microvascular endothelium: involvement of the alpha 4 beta 1 integrin.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(3):1573-81.