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Philip Branton

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.8 Million pre-calculated profiles free of charge to researchers worldwide.

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Living Beings

Anatomy

Chemicals & Drugs

Phenomena

Phosphorylation

Genes & Molecular Sequences

Amino Acid Sequence

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Physiology

Viral Cell Transformation

Procedures

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Co-Publications
Name
13
Marcellus, Richard
11
Teodoro, Jose
11
Shore, Gordon
8
Tremblay, Michel
7
Blanchette, Paola
7
Querido, E
5
Lavoie, Josée
5
Boivin, Diane
5
Bacchetti, Silvia
4
Dobner, Thomas
4
Ketner, Gary
4
Lai, A
4
Nguyen, Mai
4
Binda, Olivier
3
Conaway, Joan Weliky

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Publications

TOP 3
Dallaire Frédéric; Blanchette Paola; Branton Philip E
A proteomic approach to identify candidate substrates of human adenovirus E4orf6-E1B55K and other viral cullin-based E3 ubiquitin ligases.
Li Suiyang; Brignole Claudine; Marcellus Richard; Thirlwell Sara; Binda Olivier; McQuoid Monica J; Ashby Danita; Chan Helen; Zhang Zhiying; Miron Marie-Joëlle; Pallas David C; Branton Philip E
The adenovirus E4orf4 protein induces G2/M arrest and cell death by blocking protein phosphatase 2A activity regulated by the B55 subunit.
Dallaire Frédéric; Blanchette Paola; Groitl Peter; Dobner Thomas; Branton Philip E
Identification of integrin alpha3 as a new substrate of the adenovirus E4orf6/E1B 55-kilodalton E3 ubiquitin ligase complex.

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All Publications

2009: Dallaire Frédéric; Blanchette Paola; Branton Philip E
A proteomic approach to identify candidate substrates of human adenovirus E4orf6-E1B55K and other viral cullin-based E3 ubiquitin ligases.
Journal of virology 2009;83(23):12172-84.
2009: Li Suiyang; Brignole Claudine; Marcellus Richard; Thirlwell Sara; Binda Olivier; McQuoid Monica J; Ashby Danita; Chan Helen; Zhang Zhiying; Miron Marie-Joëlle; Pallas David C; Branton Philip E
The adenovirus E4orf4 protein induces G2/M arrest and cell death by blocking protein phosphatase 2A activity regulated by the B55 subunit.
Journal of virology 2009;83(17):8340-52.
2009: Dallaire Frédéric; Blanchette Paola; Groitl Peter; Dobner Thomas; Branton Philip E
Identification of integrin alpha3 as a new substrate of the adenovirus E4orf6/E1B 55-kilodalton E3 ubiquitin ligase complex.
Journal of virology 2009;83(11):5329-38.
2009: Miron Marie-Joëlle; Blanchette Paola; Groitl Peter; Dallaire Frederic; Teodoro Jose G; Li Suiyang; Dobner Thomas; Branton Philip E
Localization and importance of the adenovirus E4orf4 protein during lytic infection.
Journal of virology 2009;83(4):1689-99.
2009: Blanchette Paola; Branton Philip E
Manipulation of the ubiquitin-proteasome pathway by small DNA tumor viruses.
Virology 2009;384(2):317-23.
2009: Li S; Szymborski A; Miron M-J; Marcellus R; Binda O; Lavoie J N; Branton P E
The adenovirus E4orf4 protein induces growth arrest and mitotic catastrophe in H1299 human lung carcinoma cells.
Oncogene 2009;28(3):390-400.
2008: Binda O; Nassif C; Branton P E
SIRT1 negatively regulates HDAC1-dependent transcriptional repression by the RBP1 family of proteins.
Oncogene 2008;27(24):3384-92.
2008: Blanchette Paola; Kindsmüller Kathrin; Groitl Peter; Dallaire Frédéric; Speiseder Thomas; Branton Philip E; Dobner Thomas
Control of mRNA export by adenovirus E4orf6 and E1B55K proteins during productive infection requires E4orf6 ubiquitin ligase activity.
Journal of virology 2008;82(6):2642-51.
2008: Branton Philip E
Does Canadian research investment relate to cancer burden?
The lancet oncology 2008;9(2):82-3.
2007: Cheng Chi Ying; Blanchette Paola; Branton Philip E
The adenovirus E4orf6 E3 ubiquitin ligase complex assembles in a novel fashion.
Virology 2007;364(1):36-44.
2006: Binda Olivier; Roy Jean-Sébastien; Branton Philip E
RBP1 family proteins exhibit SUMOylation-dependent transcriptional repression and induce cell growth inhibition reminiscent of senescence.
Molecular and cellular biology 2006;26(5):1917-31.
2004: Blanchette Paola; Cheng Chi Ying; Yan Qin; Ketner Gary; Ornelles David A; Dobner Thomas; Conaway Ronald C; Conaway Joan Weliky; Branton Philip E
Both BC-box motifs of adenovirus protein E4orf6 are required to efficiently assemble an E3 ligase complex that degrades p53.
Molecular and cellular biology 2004;24(21):9619-29.
2004: Miron Marie-Joëlle; Gallouzi Imed-Eddine; Lavoie Josée N; Branton Philip E
Nuclear localization of the adenovirus E4orf4 protein is mediated through an arginine-rich motif and correlates with cell death.
Oncogene 2004;23(45):7458-68.
2002: Robert Amélie; Miron Marie-Joëlle; Champagne Claudia; Gingras Marie-Claude; Branton Philip E; Lavoie Josée N
Distinct cell death pathways triggered by the adenovirus early region 4 ORF 4 protein.
The Journal of cell biology 2002;158(3):519-28.
2001: Querido E; Blanchette P; Yan Q; Kamura T; Morrison M; Boivin D; Kaelin W G; Conaway R C; Conaway J W; Branton P E
Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex.
Genes & development 2001;15(23):3104-17.
2001: Branton P E; Roopchand D E
The role of adenovirus E4orf4 protein in viral replication and cell killing.
Oncogene 2001;20(54):7855-65.
2001: Roopchand D E; Lee J M; Shahinian S; Paquette D; Bussey H; Branton P E
Toxicity of human adenovirus E4orf4 protein in Saccharomyces cerevisiae results from interactions with the Cdc55 regulatory B subunit of PP2A.
Oncogene 2001;20(38):5279-90.
2001: Kamura T; Burian D; Yan Q; Schmidt S L; Lane W S; Querido E; Branton P E; Shilatifard A; Conaway R C; Conaway J W
Muf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase.
The Journal of biological chemistry 2001;276(32):29748-53.
2001: Lai A; Kennedy B K; Barbie D A; Bertos N R; Yang X J; Theberge M C; Tsai S C; Seto E; Zhang Y; Kuzmichev A; Lane W S; Reinberg D; Harlow E; Branton P E
RBP1 recruits the mSIN3-histone deacetylase complex to the pocket of retinoblastoma tumor suppressor family proteins found in limited discrete regions of the nucleus at growth arrest.
Molecular and cellular biology 2001;21(8):2918-32.
2001: Querido E; Morrison M R; Chu-Pham-Dang H; Thirlwell S W; Boivin D; Branton P E;
Identification of three functions of the adenovirus e4orf6 protein that mediate p53 degradation by the E4orf6-E1B55K complex.
Journal of virology 2001;75(2):699-709.
2000: Querido E; Chu-Pham-Dang H; Branton P E
Identification and elimination of an aberrant splice product from cDNAs encoding the human adenovirus type 5 E4orf6 protein.
Virology 2000;275(2):263-6.
2000: Marcellus R C; Chan H; Paquette D; Thirlwell S; Boivin D; Branton P E
Induction of p53-independent apoptosis by the adenovirus E4orf4 protein requires binding to the Balpha subunit of protein phosphatase 2A.
Journal of virology 2000;74(17):7869-77.
2000: Kim J; Lee J M; Branton P E; Pelletier J
Modulation of EWS/WT1 activity by the v-Src protein tyrosine kinase.
FEBS letters 2000;474(2-3):121-8.
1999: Kim J; Lee J M; Branton P E; Pelletier J
Modification of EWS/WT1 functional properties by phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(25):14300-5.
1999: Lai A; Lee J M; Yang W M; DeCaprio J A; Kaelin W G; Seto E; Branton P E
RBP1 recruits both histone deacetylase-dependent and -independent repression activities to retinoblastoma family proteins.
Molecular and cellular biology 1999;19(10):6632-41.
1999: Wee C; Muise E S; Coquelet O; Ennis M; Wagner J; Lemieux N; Branton P E; Nepveu A; Tremblay M L
Promoter analysis of the murine T-cell protein tyrosine phosphatase gene.
Gene 1999;237(2):351-60.
1999: Lai A; Marcellus R C; Corbeil H B; Branton P E
RBP1 induces growth arrest by repression of E2F-dependent transcription.
Oncogene 1999;18(12):2091-100.
1999: Boivin D; Morrison M R; Marcellus R C; Querido E; Branton P E
Analysis of synthesis, stability, phosphorylation, and interacting polypeptides of the 34-kilodalton product of open reading frame 6 of the early region 4 protein of human adenovirus type 5.
Journal of virology 1999;73(2):1245-53.
1999: Roulston A; Marcellus R C; Branton P E
Viruses and apoptosis.
Annual review of microbiology 1999;53():577-628.
1998: Nguyen M; Branton P E; Roy S; Nicholson D W; Alnemri E S; Yeh W C; Mak T W; Shore G C
E1A-induced processing of procaspase-8 can occur independently of FADD and is inhibited by Bcl-2.
The Journal of biological chemistry 1998;273(50):33099-102.
1998: Marcellus R C; Lavoie J N; Boivin D; Shore G C; Ketner G; Branton P E
The early region 4 orf4 protein of human adenovirus type 5 induces p53-independent cell death by apoptosis.
Journal of virology 1998;72(9):7144-53.
1998: Lavoie J N; Nguyen M; Marcellus R C; Branton P E; Shore G C
E4orf4, a novel adenovirus death factor that induces p53-independent apoptosis by a pathway that is not inhibited by zVAD-fmk.
The Journal of cell biology 1998;140(3):637-45.
1997: Ng F W; Nguyen M; Kwan T; Branton P E; Nicholson D W; Cromlish J A; Shore G C
p28 Bap31, a Bcl-2/Bcl-XL- and procaspase-8-associated protein in the endoplasmic reticulum.
The Journal of cell biology 1997;139(2):327-38.
1997: Corbeil H B; Branton P E
Characterization of an E2F-p130 complex formed during growth arrest.
Oncogene 1997;15(6):657-68.
1997: Querido E; Marcellus R C; Lai A; Charbonneau R; Teodoro J G; Ketner G; Branton P E
Regulation of p53 levels by the E1B 55-kilodalton protein and E4orf6 in adenovirus-infected cells.
Journal of virology 1997;71(5):3788-98.
1997: Teodoro J G; Branton P E
Regulation of p53-dependent apoptosis, transcriptional repression, and cell transformation by phosphorylation of the 55-kilodalton E1B protein of human adenovirus type 5.
Journal of virology 1997;71(5):3620-7.
1997: Whalen S G; Marcellus R C; Whalen A; Ahn N G; Ricciardi R P; Branton P E
Phosphorylation within the transactivation domain of adenovirus E1A protein by mitogen-activated protein kinase regulates expression of early region 4.
Journal of virology 1997;71(5):3545-53.
1997: Querido E; Teodoro J G; Branton P E
Accumulation of p53 induced by the adenovirus E1A protein requires regions involved in the stimulation of DNA synthesis.
Journal of virology 1997;71(5):3526-33.
1997: Teodoro J G; Branton P E
Regulation of apoptosis by viral gene products.
Journal of virology 1997;71(3):1739-46.
1996: Marcellus R C; Teodoro J G; Charbonneau R; Shore G C; Branton P E
Expression of p53 in Saos-2 osteosarcoma cells induces apoptosis which can be inhibited by Bcl-2 or the adenovirus E1B-55 kDa protein.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1996;7(12):1643-50.
1996: Chen G; Branton P E; Yang E; Korsmeyer S J; Shore G C
Adenovirus E1B 19-kDa death suppressor protein interacts with Bax but not with Bad.
The Journal of biological chemistry 1996;271(39):24221-5.
1996: Marcellus R C; Teodoro J G; Wu T; Brough D E; Ketner G; Shore G C; Branton P E
Adenovirus type 5 early region 4 is responsible for E1A-induced p53-independent apoptosis.
Journal of virology 1996;70(9):6207-15.
1996: Whalen S G; Marcellus R C; Barbeau D; Branton P E
Importance of the Ser-132 phosphorylation site in cell transformation and apoptosis induced by the adenovirus type 5 E1A protein.
Journal of virology 1996;70(8):5373-83.
1996: Duplay P; Alcover A; Fargeas C; Sékaly R P; Branton P E
An activated epidermal growth factor receptor/Lck chimera restores early T cell receptor-mediated calcium response in a CD45-deficient T cell line.
The Journal of biological chemistry 1996;271(30):17896-902.
1996: Whalen S G; Gingras A C; Amankwa L; Mader S; Branton P E; Aebersold R; Sonenberg N
Phosphorylation of eIF-4E on serine 209 by protein kinase C is inhibited by the translational repressors, 4E-binding proteins.
The Journal of biological chemistry 1996;271(20):11831-7.
1996: Boulakia C A; Chen G; Ng F W; Teodoro J G; Branton P E; Nicholson D W; Poirier G G; Shore G C
Bcl-2 and adenovirus E1B 19 kDA protein prevent E1A-induced processing of CPP32 and cleavage of poly(ADP-ribose) polymerase.
Oncogene 1996;12(3):529-35.
1996: Lee J M; Fournel M; Veillette A; Branton P E
Association of CD45 with Lck and components of the Ras signalling pathway in pervanadate-treated mouse T-cell lines.
Oncogene 1996;12(2):253-63.
1995: Chen G; Branton P E; Shore G C
Induction of p53-independent apoptosis by hygromycin B: suppression by Bcl-2 and adenovirus E1B 19-kDa protein.
Experimental cell research 1995;221(1):55-9.
1995: Corbeil H B; Whyte P; Branton P E
Characterization of transcription factor E2F complexes during muscle and neuronal differentiation.
Oncogene 1995;11(5):909-20.
1995: Teodoro J G; Shore G C; Branton P E
Adenovirus E1A proteins induce apoptosis by both p53-dependent and p53-independent mechanisms.
Oncogene 1995;11(3):467-74.
1994: Corbeil H B; Branton P E
Functional importance of complex formation between the retinoblastoma tumor suppressor family and adenovirus E1A proteins as determined by mutational analysis of E1A conserved region 2.
Journal of virology 1994;68(10):6697-709.
1994: Nguyen M; Branton P E; Walton P A; Oltvai Z N; Korsmeyer S J; Shore G C
Role of membrane anchor domain of Bcl-2 in suppression of apoptosis caused by E1B-defective adenovirus.
The Journal of biological chemistry 1994;269(24):16521-4.
1994: Takayesu D; Teodoro J G; Whalen S G; Branton P E
Characterization of the 55K adenovirus type 5 E1B product and related proteins.
The Journal of general virology 1994;75 ( Pt 4)():789-98.
1994: Barbeau D; Charbonneau R; Whalen S G; Bayley S T; Branton P E
Functional interactions within adenovirus E1A protein complexes.
Oncogene 1994;9(2):359-73.
1994: Teodoro J G; Halliday T; Whalen S G; Takayesu D; Graham F L; Branton P E
Phosphorylation at the carboxy terminus of the 55-kilodalton adenovirus type 5 E1B protein regulates transforming activity.
Journal of virology 1994;68(2):776-86.
1993: Dumont D J; Marcellus R C; Bayley S T; Branton P E
Role of phosphorylation near the amino terminus of adenovirus type 5 early region 1A proteins.
The Journal of general virology 1993;74 ( Pt 4)():583-95.
1993: Rowley R B; Lee J M; Corbeil H B; Charbonneau R; Jue K; Dankort D L; Branton P E
Isolation of chicken phosphotyrosyl phosphatase cDNA sequences and identification of a brain-specific species related to human PTP zeta.
Cellular & molecular biology research 1993;39(3):209-19.
1992: Zhang S; Mak S; Branton P E
Adenovirus type 12 early region 1B proteins and metabolism of early viral mRNAs.
Virology 1992;191(2):793-802.
1992: Barbeau D; Marcellus R C; Bacchetti S; Bayley S T; Branton P E
Quantitative analysis of regions of adenovirus E1A products involved in interactions with cellular proteins.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1992;70(10-11):1123-34.
1992: Dumont D J; Branton P E
Phosphorylation of adenovirus E1A proteins by the p34cdc2 protein kinase.
Virology 1992;189(1):111-20.
1992: Zhang S; Mak S; Branton P E
Overexpression of the E1B 55-kilodalton (482R) protein of human adenovirus type 12 appears to permit efficient transformation of primary baby rat kidney cells in the absence of the E1B 19-kilodalton protein.
Journal of virology 1992;66(4):2302-9.
1991: McLorie W; McGlade C J; Takayesu D; Branton P E
Individual adenovirus E1B proteins induce transformation independently but by additive pathways.
The Journal of general virology 1991;72 ( Pt 6)():1467-71.
1990: Howe J A; Mymryk J S; Egan C; Branton P E; Bayley S T
Retinoblastoma growth suppressor and a 300-kDa protein appear to regulate cellular DNA synthesis.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(15):5883-7.
1989: Tremblay M L; Dumont D J; Branton P E
Analysis of phosphorylation sites in the exon 1 region of E1A proteins of human adenovirus type 5.
Virology 1989;169(2):397-407.
1989: Egan C; Bayley S T; Branton P E
Binding of the Rb1 protein to E1A products is required for adenovirus transformation.
Oncogene 1989;4(3):383-8.
1989: Dumont D J; Tremblay M L; Branton P E
Phosphorylation at serine 89 induces a shift in gel mobility but has little effect on the function of adenovirus type 5 E1A proteins.
Journal of virology 1989;63(2):987-91.
1989: McGlade C J; Tremblay M L; Branton P E
Mapping of a phosphorylation site in the 176R (19 kDa) early region 1B protein of human adenovirus type 5.
Virology 1989;168(1):119-27.
1988: Egan C; Jelsma T N; Howe J A; Bayley S T; Ferguson B; Branton P E
Mapping of cellular protein-binding sites on the products of early-region 1A of human adenovirus type 5.
Molecular and cellular biology 1988;8(9):3955-9.
1988: Tremblay M L; McGlade C J; Gerber G E; Branton P E
Identification of the phosphorylation sites in early region 1A proteins of adenovirus type 5 by amino acid sequencing of peptide fragments.
The Journal of biological chemistry 1988;263(13):6375-83.
1987: McGlade C J; Tremblay M L; Yee S P; Ross R; Branton P E
Acylation of the 176R (19-kilodalton) early region 1B protein of human adenovirus type 5.
Journal of virology 1987;61(10):3227-34.
1987: Egan C; Yee S P; Ferguson B; Rosenberg M; Branton P E
Binding of cellular polypeptides to human adenovirus type 5 E1A proteins produced in Escherichia coli.
Virology 1987;160(1):292-6.
1985: Branton P E; Rowe D T
Stabilities and interrelations of multiple species of human adenovirus type 5 early region 1 proteins in infected and transformed cells.
Journal of virology 1985;56(2):633-8.
1985: Yee S P; Branton P E
Detection of cellular proteins associated with human adenovirus type 5 early region 1A polypeptides.
Virology 1985;147(1):142-53.
1985: Yee S P; Branton P E
Analysis of multiple forms of human adenovirus type 5 E1A polypeptides using an anti-peptide antiserum specific for the amino terminus.
Virology 1985;146(2):315-22.
1985: Branton P E; Evelegh M; Rowe D T; Graham F L; Bacchetti S
Protein kinase and ATP-binding activity associated with the 72-kdalton single-stranded DNA-binding protein from early region 2A of human adenovirus type 5.
Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire 1985;63(9):941-52.
1985: Tremblay M L; Yee S P; Persson R H; Bacchetti S; Smiley J R; Branton P E
Activation and inhibition of expression of the 72,000-Da early protein of adenovirus type 5 in mouse cells constitutively expressing an immediate early protein of herpes simplex virus type 1.
Virology 1985;144(1):35-45.
1985: Branton P E; Bayley S T; Graham F L
Transformation by human adenoviruses.
Biochimica et biophysica acta 1985;780(1):67-94.
1984: Downey J F; Evelegh C M; Branton P E; Bayley S T
Peptide maps and N-terminal sequences of polypeptides from early region 1A of human adenovirus 5.
Journal of virology 1984;50(1):30-7.
1984: Rowe D T; Branton P E; Graham F L
The kinetics of synthesis of early viral proteins in KB cells infected with wild-type and transformation-defective host-range mutants of human adenovirus type 5.
The Journal of general virology 1984;65 ( Pt 3)():585-97.
1984: Rowe D T; Branton P E; Yee S P; Bacchetti S; Graham F L
Establishment and characterization of hamster cell lines transformed by restriction endonuclease fragments of adenovirus 5.
Journal of virology 1984;49(1):162-70.
1984: Graham F L; Rowe D T; McKinnon R; Bacchetti S; Ruben M; Branton P E
Transformation by human adenoviruses.
Journal of cellular physiology. Supplement 1984;3():151-63.
1983: Yee S P; Branton P E
Co-purification of protein kinase activity with the 58 000 Dalton polypeptide coded for by the early 1B region of human adenovirus type 5.
The Journal of general virology 1983;64 (Pt 10)():2305-9.
1983: Rowe D T; Graham F L; Branton P E
Intracellular localization of adenovirus type 5 tumor antigens in productively infected cells.
Virology 1983;129(2):456-68.
1983: Rowe D T; Yee S P; Otis J; Graham F L; Branton P E
Characterization of human adenovirus type 5 early region 1A polypeptides using antitumor sera and an antiserum specific for the carboxy terminus.
Virology 1983;127(2):253-71.
1983: Yee S P; Rowe D T; Tremblay M L; McDermott M; Branton P E
Identification of human adenovirus early region 1 products by using antisera against synthetic peptides corresponding to the predicted carboxy termini.
Journal of virology 1983;46(3):1003-13.
1983: Malette P; Yee S P; Branton P E
Studies on the phosphorylation of the 58000 dalton early region 1B protein of human adenovirus type 5.
The Journal of general virology 1983;64(Pt 5):1069-78.
1981: Branton P E; Lassam N J; Downey J F; Yee S P; Graham F L; Mak S; Bayley S T
Protein kinase activity immunoprecipitated from adenovirus infected cells by sera from tumor-bearing hamsters.
Journal of virology 1981;37(2):601-8.
1981: Yee S P; Branton P E
External cell surface protein phosphorylation in normal and Rous sarcoma virus transformed chick embryo fibroblasts.
Journal of cellular physiology 1981;106(1):149-63.

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